FedInvent™ Patents
Patent Details for Tuesday, January 25, 2005
This page was updated on Sunday, March 26, 2023 at 07:44 PM GMT
Department of Defense (DOD)
| US 06845551 | Mandelcorn et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lyon Mandelcorn (Pittsburgh, Pennsylvania); John Bowers (Cooperstown, New York); Eugene R. Danielson (Canton, Michigan); Stephen R. Gurkovich (Eldersburg, Maryland); Kenneth C. Radford (Gambrills, Maryland) |
| ABSTRACT | There is disclosed herein a high voltage and high temperature power electronics capacitor which comprises one or more insulator layers of mica paper, and one or more metal conductor layers, all dispersed in a pressurized environment of a nonreactive and high voltage strength gas maintained at near ambient to about 405.2 kPa of pressure. The insulator and conductor layers are isolated and separated from one another by the alternating placement of conductor layers between said insulator layers. These capacitors are readily packaged for commercial use in containers or housings of almost any geometric form and any material of construction. Moreover, low inductance ceramic bushings can be employed on these containers for establishing external electrical contacts. These capacitors can be economically manufactured and used in large commercial volumes with currently available materials and production methods. |
| FILED | Thursday, June 12, 2003 |
| APPL NO | 10/459165 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/25.420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845566 | Clements et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marvin W. Clements (Portsmouth, Rhode Island); Paul E. Moody (Barrington, Rhode Island) |
| ABSTRACT | A feeler gage including a pin member having a first end and an opposing end with a gage connected to the opposing end of the pin member. The gage has a first end connected to the pin and a free end projecting past a peripheral dimension of the pin. An indicator is formed on the first end of the pin member in alignment with a longitudinal axis of the gage for determining a position of the gage upon rotation of the pin member. The gage is of a predetermined thickness and is aligned with the indicator formed at the first end of the pin member. Rotation of the pin member correspondingly rotates the gage of the pin member. If the gage rotates freely, then a gap is determined to be present in the area where the gage is rotated through. If the gage does not rotate freely, then no gap exists. |
| FILED | Monday, September 29, 2003 |
| APPL NO | 10/672963 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Geometrical instruments 033/501.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845671 | Hull |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew J Hull (Newport, Rhode Island) |
| ABSTRACT | A system and method is used for estimating the properties of a flexural beam. The beam is shaken transverse to its longitudinal axis. Seven frequency domain transfer functions of displacement are measured at spaced apart locations along the beam. The seven transfer functions are combined to yield closed form values of the flexural wavenumber in propagation coefficients at any test frequency. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/263294 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/574 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845714 | Smith et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brian J. Smith (Huntsville, Alabama); Kevin D. Kennedy (Huntsville, Alabama) |
| ABSTRACT | On-Board Power Generation System for a Guided Projectile eliminates the need for batteries as a power source to power the guiding mechanism residing inside the projectile. Instead, an electrical generator and a wind-driven turbine to drive the generator are utilized to produce power. In this way, a small portion of the projectile's kinetic energy is converted into electrical energy. The power thusly produced is, then, coupled to the guiding means. The projectile is appropriately configured to accommodate therein the power generaion system and air inlets and exhaust ports that are necessary to enable the system to operate. |
| FILED | Friday, January 09, 2004 |
| APPL NO | 10/751494 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/208 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845728 | Horton |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Duane M. Horton (Portsmouth, Rhode Island) |
| ABSTRACT | A submarine mast simulator as part of a buoyant tow body having a hydrodynamically shaped shell. The mast simulator includes a rigid lower mast section and an inflatable upper mast section extendable from the tow body. A plurality of stabilizer fins extend radially from the tail of the tow body, the fins being actuated to cause the ascent and descent of the tow body. A pressure sensor is positioned on an outer surface of the tow body for detecting a depth of the tow body, and a motor with controller is housed within the tow body, the controller initiating extension of the mast simulator in response to a depth indication. |
| FILED | Monday, October 06, 2003 |
| APPL NO | 10/679678 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/244 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845947 | Reese, Jr. et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Milton L. Reese, Jr. (La Plata, Maryland); Edward G. Tersine (Indian Head, Maryland) |
| ABSTRACT | A method of removing a canopy from a cockpit of an aircraft comprising providing an airbag in the cockpit adjacent the canopy; inflating the airbag; and as the airbag inflates, applying a force to the canopy from the inflating airbag to thereby jettison the canopy. |
| FILED | Thursday, October 09, 2003 |
| APPL NO | 10/681499 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845951 | Herman |
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| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Paul Andrew Herman (Hermosa Beach, California) |
| ABSTRACT | A method of controlling pointing for a flexible structure such as a satellite includes: providing feedforward and reference inputs of a pointing control system with prefilters; and scheduling the prefilters and a bang-bang input to the pointing control system as a function of a desired input. |
| FILED | Monday, April 08, 2002 |
| APPL NO | 10/118705 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846345 | Keller et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Teddy M. Keller (Fairfax Station, Virginia); Syed B. Qadri (Fairfax Station, Virginia) |
| ABSTRACT | A process of making metal nanoparticles comprising the steps of: providing a precursor composition comprising at least one metallic compound and at least one organic compound; wherein the organic compound is selected from the group consisting of an ethynyl compound, a metal-ethynyl complex, and combinations thereof, wherein the precursor composition is a liquid or solid at room temperature; and heating the precursor composition under conditions effective to produce metal nanoparticles. A metal nanoparticle composition comprising metal nanoparticles dispersed homogenously in a matrix selected from the group consisting of ethynyl polymer, crosslinked ethynyl polymer, amorphous carbon, carbon nanotubes, carbon nanoparticles, graphite, and combinations thereof. |
| FILED | Friday, July 26, 2002 |
| APPL NO | 10/216469 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/255 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846372 | Guirguis |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Raafat H. Guirguis (Fairfax, Virginia) |
| ABSTRACT | The invention, as embodied herein, comprises a new composition that provides different outputs depending upon the level of stimulus supplied to the composition. More specifically, if the composition is subjected to a weak shock, the composition produces fragments that burn upon their surfaces. If the composition is subjected to a strong shock, the bulk of the fragments will initiate, and, depending upon the make-up of the fragments, an explosive, propellant, or pyrotechnic, a different output will result. |
| FILED | Monday, March 31, 2003 |
| APPL NO | 10/401890 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive and thermic compositions or charges 149/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846633 | Rastogi et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Vipin K. Rastogi (Bel Air, Maryland); Tu-Chen Cheng (Timonium, Maryland) |
| ABSTRACT | The invention provides purified and isolated DNA fragments from Bacillus anthracis chromosomal DNA, primer sets and probes derived therefrom, as well as kits and detection methods for B. anthracis. The methods of the invention provide for specific detection of anthrax over closely related strains of Bacillus, as well as accurate detection of low numbers of B. anthracis in an environmental sample containing large amounts of non-specific DNA. The invention is applicable to food, health care, and military applications. |
| FILED | Monday, September 09, 2002 |
| APPL NO | 10/241384 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846691 | Hsu et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Wan-Thai Hsu (Ann Arbor, Michigan); John R. Clark (Novi, Michigan); Clark T. C. Nguyen (Ann Arbor, Michigan) |
| ABSTRACT | A method and resulting formed device are disclosed wherein the method combines polysilicon surface-micromachining with metal electroplating technology to achieve a capacitively-driven, lateral micromechanical resonator with submicron electrode-to-resonator capacitor gaps. Briefly, surface-micromachining is used to achieve the structural material for a resonator, while conformal metal-plating is used to implement capacitive transducer electrodes. This technology makes possible a variety of new resonator configurations, including disk resonators and lateral clamped-clamped and free-free flexural resonators, all with significant frequency and Q advantages over vertical resonators. In addition, this technology introduces metal electrodes, which greatly reduces the series resistance in electrode interconnects, thus, minimizing Q-loading effects while increasing the power handling ability of micromechanical resonators. |
| FILED | Thursday, July 24, 2003 |
| APPL NO | 10/625992 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/48 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846926 | Koppes et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William M. Koppes (Adelphi, Maryland); Michael E. Sitzmann (Adelphi, Maryland) |
| ABSTRACT | The present invention includes a salt compound having the chemical formula: having a tricyclic structure with the third ring having either six or seven atoms. |
| FILED | Monday, May 19, 2003 |
| APPL NO | 10/439805 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/198 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847024 | Petrenko |
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| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Victor F. Petrenko (Lebanon, New Hampshire) |
| ABSTRACT | A first electrode is separated from a second electrode by an interelectrode space. The interelectrode space does not exceed 3 mm, and preferably does not exceed 100 μm. Liquid water fills the interelectrode space, thereby electrically connecting the first electrode and the second electrode. A power supply, preferably low-frequency AC, is connected to the first and second electrodes, generating a current through the water in the interelectrode space. The applied electric power prevents freezing of a thin liquid water layer in the interelectrode space, thereby preventing ice formation. |
| FILED | Thursday, October 04, 2001 |
| APPL NO | 09/970555 |
| ART UNIT | 3742 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric heating 219/770 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847060 | Welser et al. |
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| ASSIGNEE(S) | Kopin Corporation (Taunton, Massachusetts) |
| INVENTOR(S) | Roger E. Welser (Providence, Rhode Island); Paul M. Deluca (Providence, Rhode Island); Charles R. Lutz (Seekonk, Massachusetts); Kevin S. Stevens (Providence, Rhode Island) |
| ABSTRACT | A semiconductor material which has a high carbon dopant concentration includes gallium, indium, arsenic and nitrogen. The disclosed semiconductor materials have a low sheet resistivity because of the high carbon dopant concentrations obtained. The material can be the base layer of gallium arsenide-based heterojunction bipolar transistors and can be lattice-matched to gallium arsenide emitter and/or collector layers by controlling concentrations of indium and nitrogen in the base layer. The base layer can have a graded band gap that is formed by changing the flow rates during deposition of III and V additive elements employed to reduce band gap relative to different III-V elements that represent the bulk of the layer. The flow rates of the III and V additive elements maintain an essentially constant doping-mobility product value during deposition and can be regulated to obtain pre-selected base-emitter voltages at junctions within a resulting transistor. |
| FILED | Wednesday, April 10, 2002 |
| APPL NO | 10/121444 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/197 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847153 | Balizer |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Edward Balizer (Bethesda, Maryland) |
| ABSTRACT | A phase mixed thermoplastic polyurethane elastomer is provided for use in tranducers including underwater transducers, sonars and other electrostriction driven devices. The thermoplastic polyurethane elastomer includes an isocyanate, a butanediol, a polytetramethylene ether glycol, and a polyhydric alcohol. The thermoplastic polyurethane elastomer being made by adding the polytetramethylene ether glycol to isocyanate to form a mixture, then holding said mixture of the polytetramethylene ether glycol and isocyanate to a predetermined temperature for a predetermined time, degassing the mixture and sealing the mixture, measuring the percent free isocyanate to a predetermined molar ratio with the polytetramethylene ether glycol, chain extending the mixture into a first polymer with the butanediol and the polyhydric alcohol, adjusting the stoichiometry of said chain extender to a predetermined isocyanate index to avoid crosslinking, and postcuring the resin of the first polymer for a predetermined time and temperature. |
| FILED | Thursday, May 30, 2002 |
| APPL NO | 10/161991 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847164 | Janaway et al. |
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| ASSIGNEE(S) | Applied Matrials, Inc. (Santa Clara, California) |
| INVENTOR(S) | Gordon Janaway (Tucson, Arizona); Steven Coyle (Alameda, California) |
| ABSTRACT | An electron beam source has a photocathode with a photoemitter material having a work function, and with a beam receiving portion and an electron emitting portion. A first light source directs a first light beam onto the beam receiving portion of the photocathode to generate an electron beam from the electron emitting portion. The first light beam has a wavelength λ1 such that hc/λ1 is at least about the work function of the photoemitter material, where ‘h’ is Planck's constant and ‘c’ is the speed of light. A second light source directs a second light beam onto the beam receiving portion of the photocathode, such as onto the beam receiving portion, to stabilize the electron beam. The second light beam having a wavelength λ2 such that hc/λ2 is less than about the work function of the photoemitter material. |
| FILED | Tuesday, December 10, 2002 |
| APPL NO | 10/316970 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/542 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847211 | Muhitch et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph M. Muhitch (Exeter, Rhode Island); Edward W. Wilbur, Jr. (Bristol, Rhode Island) |
| ABSTRACT | An apparatus and method for calibrating three-phase voltage spike waveforms used in testing three-phase electrical devices. The apparatus includes a circuit having a plurality of phase voltage lines and a ground line. Phase voltage outputs and a ground output are provided for connection to a device under test. A selection circuit selects one of the phase voltage lines and provides a synchronization voltage signal based on the other lines. A voltage spike generator is joined to the selection circuit for generating a voltage spike waveform synchronized with the voltage signal. Additional circuitry is joined to the voltage spike generator, the phase voltage lines and the outputs which applies the voltage spike waveform across the selected phase voltage line and the ground line. |
| FILED | Tuesday, August 26, 2003 |
| APPL NO | 10/652078 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847212 | Muhitch et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph M. Muhitch (Exeter, Rhode Island); Edward W. Wilbur, Jr. (Bristol, Rhode Island) |
| ABSTRACT | An apparatus and method for calibrating single phase voltage spikes used in testing single phase electrical equipment. Capacitance is selected from a capacitor network in order to adjust the single phase voltage spike so as to produce a predetermined voltage spike waveform having particular waveform characteristics that are required to perform survivability and compatibility tests. |
| FILED | Tuesday, August 26, 2003 |
| APPL NO | 10/652079 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847328 | Libonati et al. |
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| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Russell W. Libonati (Largo, Florida); Steven D. Eason (Largo, Florida) |
| ABSTRACT | An antenna element includes a section which is electrically non-conductive, a plurality of electrically conductive patches on the section which each face in a predetermined direction, a feed arrangement electrically coupled to the patches, and an annular strip of conductive material supported on the section and extending around the patches free of electrical contact therewith. A plurality of these antenna elements can be used to form an array, where one of the antenna elements has several other antenna elements provided at spaced locations around it. Each antenna element can include, on a side of the section opposite from the patches, an electrically-conductive portion with a cavity which faces the section. |
| FILED | Monday, January 27, 2003 |
| APPL NO | 10/352264 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847446 | Shilling |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Billy J. Shilling (Alexandria, Virginia) |
| ABSTRACT | The present invention describes an apparatus capable of specific detection of environmental chemicals in water and air. The apparatus combines a specific chemical sampler, encompassing selectively adsorbing material to automatically sample air or water samples and trap target chemicals, and uses Laser Induced Breakdown Spectroscopy for analysis of trapped chemicals. Operation of the apparatus is controlled by a computer interface. In order to provide the accuracy needed for chemical detection and adaptability required for field use it is required to incorporate Laser Induced Breakdown Spectroscopy with sample collection utilizing selective adsorbents. The invention provides a chemical detection device for concentrating chemical samples from water or air environments and then analyzing these samples with a low power highly portable Laser Induced Breakdown Spectroscope. |
| FILED | Tuesday, March 25, 2003 |
| APPL NO | 10/395130 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/318 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847449 | Bashkansky et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark Bashkansky (Alexandria, Virginia); John F Reintjes (Alexandria, Virginia) |
| ABSTRACT | A method and apparatus for reducing speckle due to MSL, without any loss of resolution, by averaging over different angles of the incident light at low input resolution, while collecting the backscattered light at a full resolution of a lens is described. The present invention allows discrimination against the speckle due to coherent MSL. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/307533 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/364 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847619 | Zscheile, Jr. et al. |
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| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | John Walter Zscheile, Jr. (Rockledge, Florida); Ryan Christopher Reid (Cocoa, Florida); John Schofield Buzby, Jr. (Marina Del Rey, California) |
| ABSTRACT | In a data link communications system there is provided a dual mode of operation multiple access system for communication between a plurality of spoke stations and a central hub station which generates a spoke epoch time comprising a plurality of time division slots in which a spoke station can communicate a priority interrupt request to the central hub station. The spoke epoch time comprises one or more dedicated spoke time slots in which only one hub station may transmit to the hub station to the exclusion of all other spoke stations. The spoke epoch time further comprising one or more priority interrupt request time slots in which all spoke stations can transmit priority interrupt requests to the hub station. Controller means in the hub station provides for evaluating priority interrupt requests from the spoke stations and for granting transmission access to one of said spoke stations during predetermined time slots in the next spoke epoch time. |
| FILED | Friday, May 11, 2001 |
| APPL NO | 09/854104 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847633 | Ryu et al. |
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| ASSIGNEE(S) | The DIRECTV Group, Inc. (El Segundo, California) |
| INVENTOR(S) | Bo Ryu (Moorpark, California); Yongguang Zhang (Moorpark, California) |
| ABSTRACT | A method, apparatus, article of manufacture, and a memory structure communicating information, particularly information transferred to and from an Internet host. The apparatus comprises a radio port control unit, comprising a router, and a stub. The router is communicatively coupled to transmit and receive messages with an Internet host and communicatively coupled to a packet forwarding module to accept SU-sourced messages and to provide SU-addressed messages to the packet forwarding module in a first data transfer protocol. The stub is coupled between the router and the packet forwarding module to translate messages from the first data transfer protocol to a second data transfer protocol and to translate messages from the second data transfer protocol to the first data transfer protocol. The method comprises the steps of receiving a data packet having a data payload, determining if the data payload is a loss-sensitive message or a delay-sensitive message, configuring the data packet to indicate that an acknowledge message is required if the day payload is a loss-sensitive message and configuring the data packet to indicate that the acknowledgement message is not required if the data payload is a delay sensitive message, and transmitting the data packet. |
| FILED | Friday, February 26, 1999 |
| APPL NO | 09/258435 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/352 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847699 | Rigali et al. |
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| ASSIGNEE(S) | Advanced Ceramics Research, Inc. (Tucson, Arizona) |
| INVENTOR(S) | Mark J. Rigali (Tucson, Arizona); Manish P. Sutaria (Philadelphia, Pennsylvania); E. Greg Hilmas (Rolla, Missouri); Anthony C. Mulligan (Tucson, Arizona); Marlene Platero-AllRunner (Tucson, Arizona); Mark M. Opeka (Bethseda, Maryland) |
| ABSTRACT | Fibrous monolith composites suitable for use in high temperature environments and/or harsh chemical environments are provided, along with methods of preparation thereof. The fibrous monolith composites exhibit such beneficial properties as enhanced strength, corrosion resistance, thermal shock resistance and thermal cycling tolerance. |
| FILED | Tuesday, December 04, 2001 |
| APPL NO | 10/013601 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847728 | Tao et al. |
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| ASSIGNEE(S) | Sarnoff Corporation (Princeton, New Jersey) |
| INVENTOR(S) | Hai Tao (Santa Cruz, California); Harpreet Singh Sawhney (West Windsor, New Jersey); Rakesh Kumar (Monmouth Junction, New Jersey) |
| ABSTRACT | A method of generating a dynamic depth map for a sequence of images from multiple cameras models a scene as a collection of 3D piecewise planar surface patches induced by color based image segmentation. This representation is continuously estimated using an incremental formulation in which the 3D geometric, motion, and global visibility constraints are enforced over space and time. The proposed algorithm optimizes a cost function that incorporates the spatial color consistency constraint and a smooth scene motion model. |
| FILED | Monday, December 09, 2002 |
| APPL NO | 10/315291 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847737 | Kouri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Donald J. Kouri (Houston, Texas); David K. Hoffman (Ames, Iowa); Ioannis Kakadiaris (Houston, Texas); Zhuoer Shi (Houston, Texas); DeSheng Zhang (Houston, Texas); Gemunu H. Gunaratne (Houston, Texas); Haixiang Wang (Houston, Texas); G. W. Wei (Singapore, Singapore); Zheng Bao (Shaanxi, China PRC) |
| ABSTRACT | A method for padding, filtering, denoising, image enhancing and increased time-frequency acquisition is described for digitized data of a data set where unknown data is estimated using real data by adding unknown data points in a manner that the padding routine can estimate the interior data set including known and unknown data to a given accuracy on the known data points. The method also provides filtering using non-interpolating, well-tempered distributed approximating functional (NIDAF)-low-band-pass filters. The method also provides for symmetric and/or anti-symmetric extension of the data set so that the data set may be better refined and can be filtered by Fourier and other type of low frequency or harmonic filters. |
| FILED | Friday, March 12, 1999 |
| APPL NO | 09/266963 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847925 | Ottusch et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | John Jacob Ottusch (Malibu, California); Stephen M. Wandzura (Agora Hills, California); Harry F. Contopanagos (Santa Monica, California); John F. Visher (Maibu, California); Vladimir Rokhlin (Santa Monica, Connecticut) |
| ABSTRACT | A computer program product, an apparatus, and a method for modeling equivalent surface sources on a closed, arbitrarily shaped object that result from the imposition of an arbitrary time-harmonic incident field (e.g., a radar wave) are provided. An object divided into by a plurality of patches 302 and parameters for the incident field and the properties of the object 304 are provided to the system. Next, the system produces a discretized representation of a well-conditioned boundary integral equation in the form of a well-conditioned matrix equation, modeling the interaction between the incident field and the object 306. The well-conditioned linear system is solved numerically to determine equivalent surface sources on the object 308. The equivalent sources may then be used to determine electromagnetic fields resulting therefrom 310. The invention provides improved computational efficiency as well as increased modeling accuracy by effectively reducing the numerical precision necessary. |
| FILED | Friday, June 15, 2001 |
| APPL NO | 09/882817 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 06846306 | Haas et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Kurt Haas (Goshen, New York); Wun Chey Sin (Huntington, New York); Ashkan Javaherian (Huntington, New York); Zheng Li (Huntington, New York); Hollis Cline (Cold Spring Harbor, New York) |
| ABSTRACT | A single cell electroporation assembly and method involve delivery of a substance into a single cell. The substance is combined into an electroporation fluid and placed into a container having a distal opening. The distal opening of the container is placed in proximity to a target cell. Electrical pulses are delivered between a first electrode which is at least partially disposed in the container, and a second electrode outside the cell, the cell being positioned between the distal opening and the second electrode. The electrical pulses induce temporary formation of pores in the cell membrane and the substance enters the cell through the pores by passive diffusion or by active electrophoretic motion. |
| FILED | Tuesday, October 10, 2000 |
| APPL NO | 09/685310 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/522 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846481 | Gaertig et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Jacek Gaertig (Athens, Georgia); Harry W. Dickerson, Jr. (Athens, Georgia); Theodore G. Clark (Ithaca, New York) |
| ABSTRACT | The ciliated protozoan Tetrahymena exemplifies a recombinant system for the expression of heterologous nucleic acids, preferably on the plasma membrane surface. Integration of a heterlogous nucleic acid into the β-tubulin gene, BTU1, of a paclitaxel-sensitive T. thermophila mutant that possesses btu1-1K350M β-tubulin allele allows screening for transformants using negative selection, as transformants have restored paclitaxel resistance. Transgenic ciliated protozoa of the invention can serve as live vaccines. For example, transgenic Tetrahymena expressing Ichthyophthirius multifiliis i-antigen protein on their surface are effective vehicles for vaccination of freshwater fish against infection by I. multifiliis. |
| FILED | Friday, February 04, 2000 |
| APPL NO | 09/498612 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846488 | Russell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Michael W. Russell (East Amberst, New York); Terry D. Connell (Williamsville, New York) |
| ABSTRACT | The present invention provides methods of inducing immune responses by recombinant antigen-enterotoxin chimeric mucosal immunogens that contain the A2/B subunits of cholera toxin or heat-labile type II toxins. These chimeric immunogens differentially enhance antibody secretion, cytokine production, as well as B7-dependent co-stimulation of T cells and CD40L expression on CD4+ T cells. |
| FILED | Tuesday, April 03, 2001 |
| APPL NO | 09/825105 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/192.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846621 | Oberste et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Steven Oberste (Lilburn, Georgia); Kaija Maher (Atlanta, Georgia); David R. Kilpatrick (Norcross, Georgia); Mark A. Pallansch (Lilburn, Georgia) |
| ABSTRACT | The present invention discloses a method for detecting the presence of an enterovirus in a clinical sample. The invention additionally discloses a method for typing an enterovirus in a clinical sample. Both methods employ a set of primer oligonucleotides for reverse transcription and amplification that hybridize to conserved regions of the enterovirus genome, and that provide amplicons that include significant portions of the VP1 region that are characteristic of the various serotypes. In the typing method, the invention further provides a database consisting of nucleotide sequences from prototypical enteroviral serotypes, which is used to type the clinical sample by comparing the sequence of its amplicon with each prototypical sequence in the database. The invention additionally provides mixtures of primer oligonucleotides, and a kit for use in conducting the typing method that includes a mixture of the primer oligonucleotides. |
| FILED | Friday, March 24, 2000 |
| APPL NO | 09/937862 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846636 | Argraves et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | American National Red Cross (Falls Church, Virginia); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); MUSC Foundation for Research Development (Charleston, South Carolina) |
| INVENTOR(S) | William S. Argraves (Charleston, South Carolina); Samar Hammad (Charleston, South Carolina); Steingrimur Stefansson (Gaithersburg, Maryland); Bryan Brewer (North Bethesda, Maryland); Alan Remaley (Bethesda, Maryland) |
| ABSTRACT | The present invention provides an isolated mammalian receptor which specifically binds a high density lipoprotein holoparticle, comprising a subunit of approximately 45-600 kDa molecular weight and one or more subunits selected from the group consisting of a subunit of approximately 40-50 kDa molecular weight, a subunit of approximately 120 kDa molecular weight and a subunit of approximately 400 kDa molecular weight. In addition, the present invention provides a method of screening a substance for the ability to modulate the HDL holoparticle binding and/or internalization activity of the receptor of this invention, comprising: a) contacting the substance with a cell producing a functional HDL receptor; and b) assaying the cell for a modulation of the HDL holoparticle binding and/or internalization activity of the receptor, whereby a modulation of the HDL holoparticle binding and/or internalization activity of the receptor identifies a substance with the ability to modulate the HDL holoparticle binding and/or internalization activity of the ADL receptor. |
| FILED | Thursday, May 13, 1999 |
| APPL NO | 09/700455 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846644 | Davis et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Davis (Princeton, Massachusetts); Benoit Derijard (Shrewsbury, Massachusetts); Michael Karin (San Diego, California); Masahiko Hibi (San Diego, California); Anning Lin (La Jolla, California) |
| ABSTRACT | An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites. |
| FILED | Friday, May 18, 2001 |
| APPL NO | 09/861098 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846646 | Haupert, Jr. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Garner T. Haupert, Jr. (Littleton, Massachusetts) |
| ABSTRACT | The present invention relates to rapid, quantitative, specific, high through-put methods for screening test substances for their ability to inhibit activity of an ouabain-resistant Na+-K+-ATPase involved in a variety of biological processes such as regulation of osmotic balance and cell volume, maintenance of the resting membrane potential, establishment of the ionic composition of cerebrospinal fluid and aqueous humor, electrical activity of muscle and nerve, and receptor-mediated endocytosis, cardiac muscle contractility, neurotransmitter metabolism and vascular muscle cell contraction. These methods can be employed to identify compounds for use in therapeutic applications for disease processes in which dysfunction of the Na+-K+-ATPase contributes to a pathological process. The present invention also includes kits which are used in the methods provided herein. The present invention further includes methods of treating or preventing diseases or disorders which are associated with dysfunction of the Na+-K+-ATPase. |
| FILED | Thursday, December 24, 1998 |
| APPL NO | 09/220913 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846651 | Fleischmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Human Genome Sciences, Inc. (Rockville, Maryland); Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Robert D. Fleischmann (Gaithersburg, Maryland); Mark D. Adams (Rockville, Maryland); Owen White (Gaithersburg, Maryland); Hamilton O. Smith (Reistertown, Maryland); J. Craig Venter (Queenstown, Maryland) |
| ABSTRACT | The present invention provides the sequencing of the entire genome of Haemophilus influenzae Rd, SEQ ID NO:1. The present invention further provides the sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use. In addition to the entire genomic sequence, the present invention identifies over 1700 protein encoding fragments of the genome and identifies, by position relative to a unique Not I restriction endonuclease site, any regulatory elements which modulate the expression of the protein encoding fragments of the Haemophilus genome. |
| FILED | Monday, June 03, 2002 |
| APPL NO | 10/158865 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846652 | Jacobs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents (Tempe, Arizona) |
| INVENTOR(S) | Bertram Jacobs (Tempe, Arizona); Teresa A. Brandt (Tempe, Arizona) |
| ABSTRACT | The present invention provides methods of use of recombinant vaccinia virus from which the region encoding the N-terminal 83 or 54 amino acids of the E3L gene product has been deleted, or amino acids at positions 44 and 66 have been mutated. Compositions comprising the recombinant vaccinia virus are also provided. |
| FILED | Friday, June 22, 2001 |
| APPL NO | 09/887295 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846659 | Croteau et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington State University Research Foundation (Pullman, Washington) |
| INVENTOR(S) | Rodney Bruce Croteau (Pullman, Washington); John E. Crock (Moscow, Idaho) |
| ABSTRACT | A cDNA encoding (E)-β-farnesene synthase from peppermint (Mentha piperita) has been isolated and sequenced, and the corresponding amino acid sequence has been determined. Accordingly, an isolated DNA sequence (SEQ ID NO:1) is provided which codes for the expression of (E)-β-farnesene synthase (SEQ ID NO:2), from peppermint (Mentha piperita). In other aspects, replicable recombinant cloning vehicles are provided which code for (E)-β-farnesene synthase, or for a base sequence sufficiently complementary to at least a portion of (E)-β-farnesene synthase DNA or RNA to enable hybridization therewith. In yet other aspects, modified host cells are provided that have been transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence encoding (E)-β-farnesene synthase. Thus, systems and methods are provided for the recombinant expression of the aforementioned recombinant (E)-β-famesene synthase that may be used to facilitate its production, isolation and purification in significant amounts. Recombinant (E)-β-farnesene synthase may be used to obtain expression or enhanced expression of (E)-β-famesene synthase in plants in order to enhance the production of (E)-β-farnesene, or may be otherwise employed for the regulation or expression of (E)-β-farnesene synthase, or the production of its product. |
| FILED | Thursday, May 17, 2001 |
| APPL NO | 09/860282 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846672 | Lambeth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | J. David Lambeth (Atlanta, Georgia); Guangjie Cheng (Doraville, Georgia) |
| ABSTRACT | The present invention relates to new genes encoding for the production of novel nox enzyme proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention. |
| FILED | Thursday, November 15, 2001 |
| APPL NO | 09/999248 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846675 | Conrad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Stratech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Paul Barth Conrad (Madison, Wisconsin); Cathy Ann-Rusmussen Ivarie (Marshall, Wisconsin); Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to in vitro cultured skin substitutes, and in particular to improved methods for organotypic culture of skin substitutes. In some embodiments, the dermal equivalent of the skin substitute is lifted to air interface of the culture prior to seeding with keratinocytes. In other embodiments, increased concentrations of collagen are used to form the dermal equivalent. In still other embodiments, optimized media are utilized to maintain the skin equivalents. |
| FILED | Friday, March 01, 2002 |
| APPL NO | 10/087641 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846799 | Nadel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jay A. Nadel (San Francisco, California); Kiyoshi Takeyama (San Francisco, California) |
| ABSTRACT | Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic molecule, an antibody, or portion of an antibody that binds to and blocks the EGF receptor. The EGF-R antagonist is preferably administered by injection in an amount sufficient to inhibit formation of goblet cells in pulmonary airways. The degranulation of goblet cells that results in airway mucus production is thereby inhibited. Assays for screening candidate agents that inhibit goblet cell proliferation are also provided. |
| FILED | Friday, July 14, 2000 |
| APPL NO | 09/616223 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846804 | Hansen |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, College Park Office of Technology Commercialization (College Park, Maryland) |
| INVENTOR(S) | J. Norman Hansen (Silver Springs, Maryland) |
| ABSTRACT | A sublancin peptide variant having a Gly-His peptide sequence fused to the C-terminal end of the mature sublancin peptide provides an affinity tag facilitating increased purification of the peptide variant from sample preparations without affecting the intracellular processing of the sublancin peptide variant, expression by a host cell or its biological activity in secreted form. This sublancin variant has specific inhibitory activity for spore outgrowth as for the native sublancin peptide. Production of the sublancin peptide variant on an industrial scale is set forth as are methods of decontaminating spore-infected areas. Methods for generating the peptide variant gene, plasmid and transformant are also described. |
| FILED | Friday, June 29, 2001 |
| APPL NO | 09/894030 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846805 | Wolfe |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Michael S. Wolfe (Newton, Massachusetts) |
| ABSTRACT | Helical peptidomimetic compounds as inhibitors of beta-amyloid production are provided. These inhibitors preferably inhibit intramembrane proteases, notably aspartyl secretases involved in the enzymatic cleavage of amyloid precursor protein (APP) to yield amyloid-β peptide. Methods are provided for making a medicament containing the compounds and for administering the compounds to treat β-amyloid-associated diseases, notably Alzheimer's disease. |
| FILED | Friday, February 14, 2003 |
| APPL NO | 10/367599 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846809 | Cristiano et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Richard J. Cristiano (Pearland, Texas); Motoyuki Yamashita (Kochi, Japan) |
| ABSTRACT | The present invention relates generally to the fields of nucleic acid transfection. More particularly, it concerns novel polycation:nucleic acid compositions, methods of preparation of such compositions and methods of transfecting cells with such compositions. |
| FILED | Tuesday, September 25, 2001 |
| APPL NO | 09/962922 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846817 | Efange |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | S. Mbua Ngale Efange (Plymouth, Minnesota) |
| ABSTRACT | The invention provides nicotine receptor agonists of formula I: wherein R1, x, y, and n have any of the values given in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising such a compound or salt, methods for preparing such a compound or salt, and methods for modulating (e.g. antagonizing or activating) nicotine receptors with such a compound or salt. |
| FILED | Friday, November 30, 2001 |
| APPL NO | 09/997718 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/228.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846840 | Skibo et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents acting for and on behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Edward B. Skibo (Mesa, Arizona); Chengguo Xing (Somerville, Massachusetts) |
| ABSTRACT | The merits of N-unsubstituted indoles and cyclopent[b]indoles as DNA-directed reductive alkylating agents are described. These systems represent a significant departure from N-substituted and pyrrolo[1,2-α] fused systems such as the mitomycins and mitosenes. The cyclopent[b]indole-based aziridinylquinone, when bearing an acetate leaving group, was found to be cytotoxic and displayed significant in vivo activity against syngeneic tumor implants. This particular analogue was unexpectedly superior to the others studied, both in terms of high specificity for the activating enzyme DT-diaphorase and in high % DNA alkylation. Alkylation by a quinone methide intermediate as well as by the aziridinyl group were examined for crosslinking. The possible metabolites of the most active indole species were prepared and found to retain cytotoxicity, strongly suggesting that in vivo activity could also be sustained. The indole systems in the present invention display selectivity for melanoma and for non small cell lung, colon, renal, and prostate cancers when administered in an effective amount. The cancer specificity observed is believed to pertain to differential substrate specificity for DT-diaphorase. |
| FILED | Monday, June 17, 2002 |
| APPL NO | 10/173343 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/411 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846911 | Kelly |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Kathleen Kelly (North Potomac, Maryland) |
| ABSTRACT | Isolated proteins comprising the T-cell surface antigen CD97 α are provided. Compositions and methods for making and detecting CD97 α are also provided. Further, the invention provides diagnostic and therapeutic methods and compositions for medical conditions involving CD97. The inventions also provides antibody compositions that bind specifically to CD97 α subunits. |
| FILED | Tuesday, January 29, 2002 |
| APPL NO | 10/059506 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846915 | Raymond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth N. Raymond (Berkeley, California); Daniel M. J. Doble (Tigard, Oregon); Christopher J. Sunderland (Menlo Park, California); Marlon Thompson (Berkeley, California) |
| ABSTRACT | The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications. |
| FILED | Friday, July 12, 2002 |
| APPL NO | 10/194502 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Organic compounds 534/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846917 | Seeberger et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter H. Seeberger (Cambridge, Massachusetts); Hernan Orgueira (Cambridge, Massachusetts); Peter Schell (Boston, Massachusetts) |
| ABSTRACT | Described is a modular, general synthetic strategy for the preparation in solution and on a solid support of heparin, heparin-like glycosaminoglycans, glycosaminoglycans and non-natural analogs of each of them. Additionally, the modular strategy provides the basis for the preparation of combinatorial libraries and parallel libraries of defined glycosaminoglycan oligosaccharides. The defined glycosaminoglycan structures may be used in high-throughput screening experiments to identify carbohydrate sequences that regulate a host of recognition and signal-transduction processes. The determination of specific sequences involved in receptor binding holds great promise for the development of molecular tools which will allow modulation of processes underlying viral entry, angiogenesis, kidney diseases and diseases of the central nervous system. Notably, the present invention enables the automated synthesis of glycosaminoglycans in much the same fashion that peptides and oligonucleotides are currently assembled. |
| FILED | Tuesday, January 22, 2002 |
| APPL NO | 10/054724 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/18.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846968 | Erwin et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Large Scale Biology Corporation (Vacaville, California) |
| INVENTOR(S) | Robert L. Erwin (Davis, California); Laurence K. Grill (Vacaville, California); Gregory P. Pogue (Vacaville, California); Thomas H. Turpen (Vacaville, California); Monto H. Kumagai (Kailua, Hawaii) |
| ABSTRACT | The invention relates to the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequences of human or animal lysosomal enzymes in a plant expression system. The plant expression system provides for post-translational modification and processing to produce a recombinant gene product exhibiting enzymatic activity. The invention is demonstrated by working examples in which transgenic tobacco plants express recombinant expression constructs comprising human glucocerebrosidase nucleotide sequences. The invention is also demonstrated by working examples in which transfected tobacco plants express recombinant viral expression constructs comprising human α galactosidase nucleotide sequences. The recombinant lysosomal enzymes produced in accordance with the invention may be used for a variety of purposes, including but not limited to enzyme replacement therapy for the therapeutic treatment of human and animal lysosomal storage diseases. |
| FILED | Wednesday, July 26, 2000 |
| APPL NO | 09/626127 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847839 | Ciaccio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Edward J. Ciaccio (Cherry Hill, New Jersey); Andrew L. Wit (Massapequa, New York); Alexis Christine Tosti (Gladstone, New Jersey) |
| ABSTRACT | A method for identifying and localizing a reentrant circuit isthmus in a heart of a subject during sinus rhythm, including: a) receiving electrogram signals from the heart during sinus rhythm via electrodes; b) storing the electrogram signals; c) creating a map based on the electrogram signals; d) finding a center reference activation location on the map; e) defining measurement vectors originating from the center reference activation location; f) selecting from the measurement vectors a primary axis vector indicating a location of the reentrant circuit isthmus in the heart; g) finding threshold points of electrogram signals on the map; h) connecting the threshold points to form a polygon indicating a shape of the reentrant circuit isthmus in the heart. |
| FILED | Monday, July 30, 2001 |
| APPL NO | 09/918216 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 6/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847844 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Mingui Sun (Pittsburgh, Pennsylvania); Robert J. Sclabassi (Pittsburgh, Pennsylvania); Marlin H. Mickle (Pittsburgh, Pennsylvania) |
| ABSTRACT | Apparatus and method of communicating data employing current pulses transmitted by an implanted device through living biological tissue to an external device. The method also contemplates transmission of current pulses from the external device through living biological tissue to an implanted device. Uniquely configured antenna electrodes are preferably employed in the implanted device. Increase in signal-to-noise ratio is achieved through synchronization. The method may be employed in diagnostic, therapeutic and general monitoring activities in connection with human beings. |
| FILED | Thursday, June 06, 2002 |
| APPL NO | 10/164517 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06845629 | Bourne et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Davis Energy Group, Inc. (Davis, California) |
| INVENTOR(S) | Richard C. Bourne (Davis, California); Brian Eric Lee (Monterey, California); Duncan Callaway (Oakland, California) |
| ABSTRACT | An evaporative heat exchanger having parallel plates that define alternating dry and wet passages. A water reservoir is located below the plates and is connected to a water distribution system. Water from the water distribution system flows through the wet passages and wets the surfaces of the plates that form the wet passages. Air flows through the dry passages, mixes with air below the plates, and flows into the wet passages before exiting through the top of the wet passages. |
| FILED | Wednesday, July 23, 2003 |
| APPL NO | 10/624633 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration 062/304 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846344 | Goyal et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit Goyal (Knoxville, Tennessee); Robert K. Williams (Knoxville, Tennessee); Donald M. Kroeger (Knoxville, Tennessee) |
| ABSTRACT | A biaxially textured alloy article having a magnetism less than pure Ni includes a rolled and annealed compacted and sintered powder-metallurgy preform article, the preform article having been formed from a powder mixture selected from the group of mixtures consisting of: at least 60 at % Ni powder and at least one of Cr powder, W powder, V powder, Mo powder, Cu powder, Al powder, Ce powder, YSZ powder, Y powder, Mg powder, and RE powder; the article having a fine and homogeneous grain structure; and having a dominant cube oriented {100}<100> orientation texture; and further having a Curie temperature less than that of pure Ni. |
| FILED | Friday, August 30, 2002 |
| APPL NO | 10/232181 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/245 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846359 | Lim et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Chong Wee Lim (Urbana, Illinois); Chan Soo Shin (Daejeon, South Korea); Ivan Georgiev Petrov (Champaign, Illinois); Joseph E. Greene (Champaign, Illinois) |
| ABSTRACT | An SixNy or SiOxNy liner is formed on a MOS device. Cobalt is then deposited and reacts to form an epitaxial CoSi2 layer underneath the liner. The CoSi2 layer may be formed through a solid phase epitaxy or reactive deposition epitaxy salicide process. In addition to high quality epitaxial CoSi2 layers, the liner formed during the invention can protect device portions during etching processes used to form device contacts. The liner can act as an etch stop layer to prevent excessive removal of the shallow trench isolation, and protect against excessive loss of the CoSi2 layer. |
| FILED | Friday, October 25, 2002 |
| APPL NO | 10/280668 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846399 | Shepodd et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia National Laboratories (Livermore, California) |
| INVENTOR(S) | Timothy J. Shepodd (Livermore, California); Leroy Whinnery, Jr. (Danville, California); William R. Even, Jr. (Livermore, California) |
| ABSTRACT | A polymer material useful as the porous dielectric medium for microfluidic devices generally and electrokinetic pumps in particular. The polymer material is produced from an inverse (water-in-oil) emulsion that creates a 3-dimensional network characterized by small pores and high internal volume, characteristics that are particularly desirable for the dielectric medium for electrokinetic pumps. Further, the material can be cast-to-shape inside a microchannel. The use of bifunctional monomers provides for charge density within the polymer structure sufficient to support electroosmotic flow. The 3-dimensional polymeric material can also be covalently bound to the channel walls thereby making it suitable for high-pressure applications. |
| FILED | Wednesday, February 28, 2001 |
| APPL NO | 09/796762 |
| ART UNIT | 1753 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/470 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846511 | Visco et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Craig P. Jacobson (El Cerrito, California); Lutgard C. DeJonghe (Lafayette, California) |
| ABSTRACT | An electrode/electrolyte structure is prepared by a plurality of methods. An unsintered (possibly bisque fired) moderately catalytic electronically-conductive or homogeneous mixed ionic electronic conductive electrode material is deposited on a layer composed of a sintered or unsintered ionically-conductive electrolyte material prior to being sintered. A layer of particulate electrode material is deposited on an unsintered (“green”) layer of electrolyte material and the electrode and electrolyte layers are sintered simultaneously, sometimes referred to as “co-firing,” under conditions suitable to fully densify the electrolyte while the electrode retains porosity. Or, the layer of particulate electrode material is deposited on a previously sintered layer of electrolyte, and then sintered. Subsequently, a catalytic material is added to the electrode structure by infiltration of an electrolcatalyst precursor (e.g., a metal salt such as a transition metal nitrate). This may be followed by low temperature firing to convert the precursor to catalyst. The invention allows for an electrode with high electronic conductivity and sufficient catalytic activity to achieve high power density in an ionic (electrochemical) device such as fuel cells and electrolytic gas separation systems. |
| FILED | Wednesday, November 26, 2003 |
| APPL NO | 10/724558 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846554 | Fryxell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Glen E. Fryxell (Kennewick, Washington); Thomas S. Zemanian (Richland, Washington); Jun Liu (West Richland, Washington); Yongsoon Shin (Richland, Washington) |
| ABSTRACT | According to the present invention, the previously known functional material having a self-assembled monolayer on a substrate has a plurality of assembly molecules each with an assembly atom with a plurality of bonding sites (four sites when silicon is the assembly molecule) wherein a bonding fraction (or fraction) of fully bonded assembly atoms (the plurality of bonding sites bonded to an oxygen atom) has a maximum when made by liquid solution deposition, for example a maximum of 40% when silicon is the assembly molecule, and maximum surface density of assembly molecules was 5 silanes per square nanometer. Note that bonding fraction and surface population are independent parameters. The method of the present invention is an improvement to the known method for making a siloxane layer on a substrate, wherein instead of a liquid phase solution chemistry, the improvement is a supercritical phase chemistry. The present invention has the advantages of greater fraction of oxygen bonds, greater surface density of assembly molecules and reduced time for reaction of about 5 minutes to about 24 hours. |
| FILED | Friday, January 17, 2003 |
| APPL NO | 10/347042 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/307.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846558 | Pham et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ai-Quoc Pham (San Jose, California); Robert S. Glass (Livermore, California); Tae H. Lee (Naperville, Illinois) |
| ABSTRACT | A dense or porous coating of material is deposited onto a substrate by forcing a colloidal suspension through an ultrasonic nebulizer and spraying a fine mist of particles in a carrier medium onto a sufficiently heated substrate. The spraying rate is essentially matched to the evaporation rate of the carrier liquid from the substrate to produce a coating that is uniformly distributed over the surface of the substrate. Following deposition to a sufficient coating thickness, a single sintering step may be used to produce a dense ceramic coating. Using this method, coatings ranging in thickness from about one to several hundred microns can be obtained. By using a plurality of compounds in the colloidal suspension, coatings of mixed composition can be obtained. By using a plurality of solutions and separate pumps and a single or multiple ultrasonic nebulizer(s), and varying the individual pumping rates and/or the concentrations of the solutions, a coating of mixed and discontinuously graded (e.g., stepped) or continuously graded layers may be obtained. This method is particularly useful for depositing ceramic coatings. Dense ceramic coating materials on porous substrates are useful in providing improved electrode performance in devices such as high power density solid oxide fuel cells. Dense ceramic coatings obtained by the invention are also useful for gas turbine blade coatings, sensors, steam electrolyzers, etc. The invention has general use in preparation of systems requiring durable and chemically resistant coatings, or coatings having other specific chemical or physical properties. |
| FILED | Monday, January 28, 2002 |
| APPL NO | 10/059852 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/336 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846639 | Miles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robin R. Miles (Danville, California); Kodumudi S. Venkateswaran (Livermore, California); Christopher K. Fuller (Livermore, California) |
| ABSTRACT | The use of impedance measurements to detect the presence of pathogens attached to antibody-coated beads. In a fluidic device antibodies are immobilized on a surface of a patterned interdigitated electrode. Pathogens in a sample fluid streaming past the electrode attach to the immobilized antibodies, which produces a change in impedance between two adjacent electrodes, which impedance change is measured and used to detect the presence of a pathogen. To amplify the signal, beads coated with antibodies are introduced and the beads would stick to the pathogen causing a greater change in impedance between the two adjacent electrodes. |
| FILED | Thursday, November 15, 2001 |
| APPL NO | 09/993870 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846644 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Davis (Princeton, Massachusetts); Benoit Derijard (Shrewsbury, Massachusetts); Michael Karin (San Diego, California); Masahiko Hibi (San Diego, California); Anning Lin (La Jolla, California) |
| ABSTRACT | An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites. |
| FILED | Friday, May 18, 2001 |
| APPL NO | 09/861098 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846659 | Croteau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington State University Research Foundation (Pullman, Washington) |
| INVENTOR(S) | Rodney Bruce Croteau (Pullman, Washington); John E. Crock (Moscow, Idaho) |
| ABSTRACT | A cDNA encoding (E)-β-farnesene synthase from peppermint (Mentha piperita) has been isolated and sequenced, and the corresponding amino acid sequence has been determined. Accordingly, an isolated DNA sequence (SEQ ID NO:1) is provided which codes for the expression of (E)-β-farnesene synthase (SEQ ID NO:2), from peppermint (Mentha piperita). In other aspects, replicable recombinant cloning vehicles are provided which code for (E)-β-farnesene synthase, or for a base sequence sufficiently complementary to at least a portion of (E)-β-farnesene synthase DNA or RNA to enable hybridization therewith. In yet other aspects, modified host cells are provided that have been transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence encoding (E)-β-farnesene synthase. Thus, systems and methods are provided for the recombinant expression of the aforementioned recombinant (E)-β-famesene synthase that may be used to facilitate its production, isolation and purification in significant amounts. Recombinant (E)-β-farnesene synthase may be used to obtain expression or enhanced expression of (E)-β-famesene synthase in plants in order to enhance the production of (E)-β-farnesene, or may be otherwise employed for the regulation or expression of (E)-β-farnesene synthase, or the production of its product. |
| FILED | Thursday, May 17, 2001 |
| APPL NO | 09/860282 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846789 | Davenhall et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
| INVENTOR(S) | Leisa B. Davenhall (Santa Fe, New Mexico); James B. Rubin (Los Alamos, New Mexico); Craig M. V. Taylor (Jemez Springs, New Mexico) |
| ABSTRACT | Composition and method for removing photoresist materials from electronic components. The composition is a mixture of at least one dense phase fluid and at least one dense phase fluid modifier. The method includes exposing a substrate to at least one pulse of the composition in a supercritical state to remove photoresist materials from the substrate. |
| FILED | Friday, April 26, 2002 |
| APPL NO | 10/133709 |
| ART UNIT | 1751 — Semiconductors/Memory |
| CURRENT CPC | Cleaning compositions for solid surfaces, auxiliary compositions therefor, or processes of preparing the compositions 510/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846909 | Mairal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Membrane Technology and Research, Inc. (Menlo Park, California) |
| INVENTOR(S) | Anurag P. Mairal (Fremont, California); Alvin Ng (Palo Alto, California); Johannes G. Wijmans (Menlo Park, California) |
| ABSTRACT | A membrane process for treating zein solutions to increase the zein concentration in the solution. The process uses a non-porous membrane that preferentially permeates the solvent and rejects the zein. Optionally, the process can be operated as a diafiltration process to yield a concentrate of high zein purity. |
| FILED | Wednesday, May 14, 2003 |
| APPL NO | 10/437589 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846915 | Raymond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth N. Raymond (Berkeley, California); Daniel M. J. Doble (Tigard, Oregon); Christopher J. Sunderland (Menlo Park, California); Marlon Thompson (Berkeley, California) |
| ABSTRACT | The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications. |
| FILED | Friday, July 12, 2002 |
| APPL NO | 10/194502 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Organic compounds 534/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846946 | Joyce et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Value Recovery, Inc. (Bridgeport, New Jersey) |
| INVENTOR(S) | Peter J. Joyce (Mullica Hill, New Jersey); Roman Bielski (Coopersburg, Pennsylvania); Marc Halpern (Cherry Hill, New Jersey) |
| ABSTRACT | A method for preparing organic products from aqueous solutions, such as waste or byproduct liquid streams and waste or byproduct gas or vapor streams, uses phase transfer catalysis to transfer a chemical species in low concentration from the aqueous solution to the organic phase or the aqueous-organic interface. The system has little or no organic solvent, and the organic phase contains an electrophile which participates in the reaction. In one embodiment, the aqueous solution is contacted with the electrophile and a phase transfer catalyst and, optionally, a pH adjusting agent in the event that the chemical species in the aqueous solution is not sufficiently ionized to react with the electrophile, and optionally an organic solvent. A method for continuously converting a chemical species involves this contacting step, separating the phases, then dividing the organic phase into the product, the phase transfer catalyst, and the optional organic solvent. |
| FILED | Friday, September 06, 2002 |
| APPL NO | 10/236382 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 558/388 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847188 | Keskula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Motors Corporation (Detroit, Michigan) |
| INVENTOR(S) | Donald H. Keskula (Webster, New York); Tien M. Doan (Columbia, Maryland); Bruce J. Clingerman (Palmyra, New York) |
| ABSTRACT | A control method for monitoring a fuel cell stack in a fuel cell system in which the actual voltage and actual current from the fuel cell stack are monitored. A preestablished relationship between voltage and current over the operating range of the fuel cell is established. A variance value between the actual measured voltage and the expected voltage magnitude for a given actual measured current is calculated and compared with a predetermined allowable variance. An output is generated if the calculated variance value exceeds the predetermined variance. The predetermined voltage-current for the fuel cell is symbolized as a polarization curve at given operating conditions of the fuel cell. Other polarization curves may be generated and used for fuel cell stack monitoring based on different operating pressures, temperatures, hydrogen quantities. |
| FILED | Wednesday, January 07, 2004 |
| APPL NO | 10/752603 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847455 | Schmitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Tony L. Schmitz (Gainesville, Florida); John F. Beckwith (Indialantic, Florida) |
| ABSTRACT | Displacement measuring interferometer systems and methods are disclosed. One or more acousto-optic modulators for receiving a laser light beam from a laser light source can be utilized to split the laser light beam into two or more laser light beams, while spatially separating frequencies thereof. One or more reflective mechanisms can be utilized to reflect one or more of the laser light beams back to the acousto-optic modulator. Interference of two or more of the laser light beams generally at the acousto-optic modulator can provide an interfered laser light beam thereof. A detector for receiving the interfered laser light beam can be utilized to provide interferometer measurement data. |
| FILED | Thursday, September 26, 2002 |
| APPL NO | 10/254567 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/486 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847463 | Malinowski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | EUV, LLC (Santa Clara, California) |
| INVENTOR(S) | Michael E. Malinowski (Livermore, California) |
| ABSTRACT | The characteristics of radiation that is reflected from carbon deposits and oxidation formations on highly reflective surfaces such as Mo/Si mirrors can be quantified and employed to detect and measure the presence of such impurities on optics. Specifically, it has been shown that carbon deposits on a Mo/Si multilayer mirror decreases the intensity of reflected HeNe laser (632.8 nm) light. In contrast, oxide layers formed on the mirror should cause an increase in HeNe power reflection. Both static measurements and real-time monitoring of carbon and oxide surface impurities on optical elements in lithography tools should be achievable. |
| FILED | Wednesday, June 05, 2002 |
| APPL NO | 10/163477 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/630 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847584 | Deason et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Bechtel BWXT Idaho, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Vance A. Deason (Idaho Falls, Idaho); Kenneth L. Telschow (Idaho Falls, Idaho) |
| ABSTRACT | A method, system and underwater camera for acoustic imaging of objects in water or other liquids includes an acoustic source for generating an acoustic wavefront for reflecting from a target object as a reflected wavefront. The reflected acoustic wavefront deforms a screen on an acoustic side and correspondingly deforms the opposing optical side of the screen. An optical processing system is optically coupled to the optical side of the screen and converts the deformations on the optical side of the screen into an optical intensity image of the target object. |
| FILED | Monday, June 30, 2003 |
| APPL NO | 10/611388 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847673 | Dane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | C. Brent Dane (Livermore, California); Georg F. Albrecht (Livermore, California); Mark D. Rotter (San Ramon, California) |
| ABSTRACT | Normal incidence stack architecture coupled with the development of diode array pumping enables the power/energy per disk to be increased, a reduction in beam distortions by orders of magnitude, a beam propagation no longer restricted to only one direction of polarization, and the laser becomes so much more amendable to robust packaging. |
| FILED | Friday, June 21, 2002 |
| APPL NO | 10/177339 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/75 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847838 | Macey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Southeastern Universities Research Assn., Inc. (Newport News, Virginia) |
| INVENTOR(S) | Daniel J. Macey (Birmingham, Alabama); Stanislaw Majewski (Grafton, Virginia); Andrew G. Weisenberger (Yorktown, Virginia); Mark Frederick Smith (Yorktown, Virginia); Brian James Kross (Yorktown, Virginia) |
| ABSTRACT | A method and apparatus for the in vivo location and tracking of a radioactive seed source during and after brachytherapy treatment. The method comprises obtaining multiple views of the seed source in a living organism using: 1) a single PSPMT detector that is exposed through a multiplicity of pinholes thereby obtaining a plurality of images from a single angle; 2) a single PSPMT detector that may obtain an image through a single pinhole or a plurality of pinholes from a plurality of angles through movement of the detector; or 3) a plurality of PSPMT detectors that obtain a plurality of views from different angles simultaneously or virtually simultaneously. The plurality of images obtained from these various techniques, through angular displacement of the various acquired images, provide the information required to generate the three dimensional images needed to define the location of the radioactive seed source within the body of the living organism. |
| FILED | Thursday, September 19, 2002 |
| APPL NO | 10/247450 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/431 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06845655 | van der Weide et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Daniel van der Weide (Madison, Wisconsin); Bjoern Rosner (Chicago, Illinois) |
| ABSTRACT | Frequency translation of microelectromechanical vibration signals such as a tip vibration signal in a scanning force microscopy system expands the versatility of existing control systems and enables new signal processing techniques. The vibration signal such as the cantilever probe tip vibration signal of a scanning force microscopy is frequency converted to a lower or higher frequency signal that is utilized to provide a control signal. |
| FILED | Monday, March 17, 2003 |
| APPL NO | 10/390334 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846084 | Grier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | David G. Grier (Chicago, Illinois); Eric R. Dufresne (Arlington, Massachusetts); Jennifer E. Curtis (Chicago, Illinois); Brian A. Koss (Chicago, Illinois) |
| ABSTRACT | A method and apparatus for control of optical trap arrays and formation of particle arrays using light that is in the visible portion of the spectrum. The method and apparatus provides a laser and a time variable diffractive optical element to allow dynamic control of optical trap arrays and consequent control of particle arrays and also the ability to manipulate singular objects using a plurality of optical traps. By avoiding wavelengths associated with strong absorption in the underlying material, creating optical traps with a continuous-wave laser, optimizing the efficiency of individual traps, and trapping extended samples at multiple points, the rate of deleterious nonlinear optical processes can be minimized. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646432 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/614 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846428 | McCaughan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Leon McCaughan (Madison, Wisconsin); Thomas F. Kuech (Madison, Wisconsin); Dovas A. Saulys (Madison, Wisconsin); Vladimir A. Joshkin (Madison, Wisconsin); Aref Chowdhury (Springfield, New Jersey) |
| ABSTRACT | Metal oxide films such as lithium niobate are formed in an amorphous state on a substrate such as lithium niobate and can be readily etched by conventional liquid or dry etchants. The amorphous film may then be converted by annealing to a crystalline form well suited to formation of electro-optical devices. |
| FILED | Thursday, March 14, 2002 |
| APPL NO | 10/097441 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Etching a substrate: Processes 216/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846445 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Byung Kim (Amherst, Massachusetts); Donggang Yao (Rochester Hills, Michigan) |
| ABSTRACT | A method for rapidly heating a mold cavity to a predetermined temperature preferably above the softening or melting temperature of the molding material prior to and during the molding stage thereby increasing moldability and improving quality of molded parts. The mold cavity is formed by two metallic halves on which high-frequency electric current is applied and an electric circuit involving the two halves is formed. Due to the proximity effect, the electrical current flows on the inner surfaces of the two cavity halves, thus rapidly heating the mold cavity. Proper use of insulation behind the cavity surface helps increase heating efficiency. Conformal on-off cooling channels provide both thermal insulation during the heating phase and rapidly cooling of the molded article during the cooling phase. |
| FILED | Wednesday, September 04, 2002 |
| APPL NO | 10/234507 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/404 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846565 | Korgel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Brian A. Korgel (Round Rock, Texas); Keith P. Johnston (Austin, Texas) |
| ABSTRACT | A method for the production of a robust, chemically stable, crystalline, passivated nanoparticle and composition containing the same, that emit light with high efficiencies and size-tunable and excitation energy tunable color. The methods include the thermal degradation of a precursor molecule in the presence of a capping agent at high temperature and elevated pressure. A particular composition prepared by the methods is a passivated silicon nanoparticle composition displaying discrete optical transitions. |
| FILED | Thursday, March 28, 2002 |
| APPL NO | 10/109578 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846682 | Heath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | James R. Heath (Santa Monica, California); R. Stanley Williams (Mountain View, California); Philip J. Kuekes (Menlo Park, California) |
| ABSTRACT | A route to the fabrication of electronic devices is provided, in which the devices consist of two crossed wires sandwiching an electrically addressable molecular species. The approach is extremely simple and inexpensive to implement, and scales from wire dimensions of several micrometers down to nanometer-scale dimensions. The device of the present invention can be used to produce crossbar switch arrays, logic devices, memory devices, and communication and signal routing devices. The present invention enables construction of molecular electronic devices on a length scale than can range from micrometers to nanometers via a straightforward and inexpensive chemical assembly procedure. The device is either partially or completely chemically assembled, and the key to the scaling is that the location of the devices on the substrate are defined once the devices have been assembled, not prior to assembly. |
| FILED | Tuesday, July 17, 2001 |
| APPL NO | 09/907314 |
| ART UNIT | 2823 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846731 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Yicheng Lu (East Brunswick, New Jersey); Haifeng Sheng (Piscataway, New Jersey); Sriram Muthukumar (Highland Park, New Jersey); Nuri William Emanetoglu (Woodbury, New Jersey); Jian Zhong (Piscataway, New Jersey) |
| ABSTRACT | In the present invention, there is provided semiconductor devices such as a Schottky UV photodetector fabricated on n-type ZnO and MgxZn1-xO epitaxial films. The ZnO and MgxZn1-xO films are grown on R-plane sapphire substrates and the Schottky diodes are fabricated on the ZnO and MgxZn1-xO films using silver and aluminum as Schottky and ohmic contact metals, respectively. The Schottky diodes have circular patterns, where the inner circle is the Schottky contact, and the outside ring is the ohmic contact. Ag Schottky contact patterns are fabricated using standard liftoff techniques, while the Al ohmic contact patterns are formed using wet chemical etching. These detectors show low frequency photoresponsivity, high speed photoresponse, lower leakage current and low noise performance as compared to their photoconductive counterparts. This invention is also applicable to optical modulators, Metal Semiconductor Field Effect Transistors (MESFETs) and more. |
| FILED | Thursday, May 30, 2002 |
| APPL NO | 10/158540 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/570 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846773 | Yokoyama et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Chikafumi Yokoyama (Tokyo, Japan); Sameer S. Bharadwaj (Minneapolis, Minnesota); Lanny D. Schmidt (Minneapolis, Minnesota) |
| ABSTRACT | A process for the production of a mono-olefin from a gaseous paraffinic hydrocarbon having at least two carbon atoms or mixtures thereof comprising reacting said hydrocarbons and molecular oxygen in the presence of a platinum catalyst. The catalyst consists essentially of platinum modified with Sn or Cu and supported on a ceramic monolith. |
| FILED | Thursday, March 20, 1997 |
| APPL NO | 08/821384 |
| ART UNIT | 1755 — Semiconductors/Memory |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/339 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846840 | Skibo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents acting for and on behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Edward B. Skibo (Mesa, Arizona); Chengguo Xing (Somerville, Massachusetts) |
| ABSTRACT | The merits of N-unsubstituted indoles and cyclopent[b]indoles as DNA-directed reductive alkylating agents are described. These systems represent a significant departure from N-substituted and pyrrolo[1,2-α] fused systems such as the mitomycins and mitosenes. The cyclopent[b]indole-based aziridinylquinone, when bearing an acetate leaving group, was found to be cytotoxic and displayed significant in vivo activity against syngeneic tumor implants. This particular analogue was unexpectedly superior to the others studied, both in terms of high specificity for the activating enzyme DT-diaphorase and in high % DNA alkylation. Alkylation by a quinone methide intermediate as well as by the aziridinyl group were examined for crosslinking. The possible metabolites of the most active indole species were prepared and found to retain cytotoxicity, strongly suggesting that in vivo activity could also be sustained. The indole systems in the present invention display selectivity for melanoma and for non small cell lung, colon, renal, and prostate cancers when administered in an effective amount. The cancer specificity observed is believed to pertain to differential substrate specificity for DT-diaphorase. |
| FILED | Monday, June 17, 2002 |
| APPL NO | 10/173343 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/411 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847024 | Petrenko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Victor F. Petrenko (Lebanon, New Hampshire) |
| ABSTRACT | A first electrode is separated from a second electrode by an interelectrode space. The interelectrode space does not exceed 3 mm, and preferably does not exceed 100 μm. Liquid water fills the interelectrode space, thereby electrically connecting the first electrode and the second electrode. A power supply, preferably low-frequency AC, is connected to the first and second electrodes, generating a current through the water in the interelectrode space. The applied electric power prevents freezing of a thin liquid water layer in the interelectrode space, thereby preventing ice formation. |
| FILED | Thursday, October 04, 2001 |
| APPL NO | 09/970555 |
| ART UNIT | 3742 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric heating 219/770 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847032 | Grier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | David G. Grier (Chicago, Illinois); Sven Holger Behrens (Mannheim, Germany) |
| ABSTRACT | A method of use for holographic optical traps or gradients in which repetitive cycling of a small number of appropriately designed arrays of traps are used for general and very complex manipulations of particles and volumes of matter. Material transport results from a process resembling peristaltic pumping, with the sequence of holographically-defined trapping or holding manifolds resembling the states of a physical peristaltic pump. |
| FILED | Friday, August 29, 2003 |
| APPL NO | 10/651370 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847737 | Kouri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Donald J. Kouri (Houston, Texas); David K. Hoffman (Ames, Iowa); Ioannis Kakadiaris (Houston, Texas); Zhuoer Shi (Houston, Texas); DeSheng Zhang (Houston, Texas); Gemunu H. Gunaratne (Houston, Texas); Haixiang Wang (Houston, Texas); G. W. Wei (Singapore, Singapore); Zheng Bao (Shaanxi, China PRC) |
| ABSTRACT | A method for padding, filtering, denoising, image enhancing and increased time-frequency acquisition is described for digitized data of a data set where unknown data is estimated using real data by adding unknown data points in a manner that the padding routine can estimate the interior data set including known and unknown data to a given accuracy on the known data points. The method also provides filtering using non-interpolating, well-tempered distributed approximating functional (NIDAF)-low-band-pass filters. The method also provides for symmetric and/or anti-symmetric extension of the data set so that the data set may be better refined and can be filtered by Fourier and other type of low frequency or harmonic filters. |
| FILED | Friday, March 12, 1999 |
| APPL NO | 09/266963 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06845605 | Taylor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Eric S. Taylor (Huntsville, Alabama); W. Neill Myers (Huntsville, Alabama); Michael A. Martin (Huntsville, Alabama) |
| ABSTRACT | An ignitor for use with the MC-1 rocket engine has a cartridge bounded by two end caps with rupture disc assemblies connected thereto. A piston assembly within the cartridge moves from one end of the cartridge during the ignition process. The inlet of the ignitor communicates with a supply taken from the discharge of the fuel pump. When the pump is initially started, the pressure differential bursts the first rupture disc to begin the movement of the piston assembly toward the discharge end. The pressurization of the cartridge causes the second rupture disc to rupture and hypergolic fluid contained within the cartridge is discharged out the ignitor outlet. |
| FILED | Monday, November 04, 2002 |
| APPL NO | 10/288800 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/39.824 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06845664 | Okojie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert S. Okojie (Strongsville, Ohio) |
| ABSTRACT | Methods of bulk manufacturing high temperature sensor sub-assembly packages are disclosed and claimed. Sensors are sandwiched between a top cover and a bottom cover so as to enable the peripheries of the top covers, sensors and bottom covers to be sealed and bound securely together are disclosed and claimed. Sensors are placed on the bottom covers leaving the periphery of the bottom cover exposed. Likewise, top covers are placed on the sensors leaving the periphery of the sensor exposed. Individual sensor sub-assemblies are inserted into final packaging elements which are also disclosed and claimed. Methods of directly attaching wires or pins to contact pads on the sensors are disclosed and claimed. Sensors, such as pressure sensors and accelerometers, and headers made out of silicon carbide and aluminum nitride are disclosed and claimed. Reference cavities are formed in some embodiments disclosed and claimed herein where top covers are not employed. |
| FILED | Thursday, October 03, 2002 |
| APPL NO | 10/263980 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Measuring and testing 073/431 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847354 | Vranish |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | John M. Vranish (Crofton, Maryland) |
| ABSTRACT | A three-dimensional (3-D) interactive display and method of forming the same, includes a transparent capaciflector (TC) camera formed on a transparent shield layer on the screen surface. A first dielectric layer is formed on the shield layer. A first wire layer is formed on the first dielectric layer. A second dielectric layer is formed on the first wire layer. A second wire layer is formed on the second dielectric layer. Wires on the first wire layer and second wire layer are grouped into groups of parallel wires with a turnaround at one end of each group and a sensor pad at the opposite end. An operational amplifier is connected to each of the sensor pads and the shield pad biases the pads and receives a signal from connected sensor pads in response to intrusion of a probe. The signal is proportional to probe location with respect to the monitor screen. |
| FILED | Tuesday, March 13, 2001 |
| APPL NO | 09/804645 |
| ART UNIT | 2673 — Printing/Measuring and Testing |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847699 | Rigali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Ceramics Research, Inc. (Tucson, Arizona) |
| INVENTOR(S) | Mark J. Rigali (Tucson, Arizona); Manish P. Sutaria (Philadelphia, Pennsylvania); E. Greg Hilmas (Rolla, Missouri); Anthony C. Mulligan (Tucson, Arizona); Marlene Platero-AllRunner (Tucson, Arizona); Mark M. Opeka (Bethseda, Maryland) |
| ABSTRACT | Fibrous monolith composites suitable for use in high temperature environments and/or harsh chemical environments are provided, along with methods of preparation thereof. The fibrous monolith composites exhibit such beneficial properties as enhanced strength, corrosion resistance, thermal shock resistance and thermal cycling tolerance. |
| FILED | Tuesday, December 04, 2001 |
| APPL NO | 10/013601 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847749 | Spremo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia); San Jose State University (San Jose, California) |
| INVENTOR(S) | Stevan M. Spremo (Campbell, California); Peter L. Fuhr (Santa Cruz, California); John F. Schipper (Palo Alto, California) |
| ABSTRACT | Method and system for controllably redirecting a light beam, having a central wavelength λ, from a first light-receiving site to a second light-receiving site. A diffraction grating is attached to or part of a piezoelectric substrate, which is connected to one or two controllable voltage difference sources. When a substrate voltage difference is changed and the diffraction grating length in each of one or two directions is thereby changed, at least one of the diffraction angle, the diffraction order and the central wavelength is controllably changed. A diffracted light beam component, having a given wavelength, diffraction angle and diffraction order, that is initially received at a first light receiving site (e.g., a detector or optical fiber) is thereby controllably shifted or altered and can be received at a second light receiving site. A polynomially stepped, chirped grating is used in one embodiment. In another embodiment, an incident light beam, having at least one of first and second wavelengths, λ1 and λ2, is received and diffracted at a first diffraction grating to provide a first diffracted beam. The first diffracted beam is received and diffracted at a second diffraction grating to produce a second diffracted beam. The second diffracted beam is received at a light-sensitive transducer, having at least first and second spaced apart light detector elements that are positioned so that, when the incident light beam has wavelength λ1 or λ2 (λ1≠λ2), the second diffracted beam is received at the first element or at the second element, respectively; change in a selected physical parameter at the second grating can also be sensed or measured. A sequence of spaced apart light detector elements can be positioned along a linear or curvilinear segment with equal or unequal spacing. |
| FILED | Friday, January 18, 2002 |
| APPL NO | 10/058873 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Optical waveguides 385/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 06846675 | Conrad et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Stratech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Paul Barth Conrad (Madison, Wisconsin); Cathy Ann-Rusmussen Ivarie (Marshall, Wisconsin); Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to in vitro cultured skin substitutes, and in particular to improved methods for organotypic culture of skin substitutes. In some embodiments, the dermal equivalent of the skin substitute is lifted to air interface of the culture prior to seeding with keratinocytes. In other embodiments, increased concentrations of collagen are used to form the dermal equivalent. In still other embodiments, optimized media are utilized to maintain the skin equivalents. |
| FILED | Friday, March 01, 2002 |
| APPL NO | 10/087641 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06846946 | Joyce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Value Recovery, Inc. (Bridgeport, New Jersey) |
| INVENTOR(S) | Peter J. Joyce (Mullica Hill, New Jersey); Roman Bielski (Coopersburg, Pennsylvania); Marc Halpern (Cherry Hill, New Jersey) |
| ABSTRACT | A method for preparing organic products from aqueous solutions, such as waste or byproduct liquid streams and waste or byproduct gas or vapor streams, uses phase transfer catalysis to transfer a chemical species in low concentration from the aqueous solution to the organic phase or the aqueous-organic interface. The system has little or no organic solvent, and the organic phase contains an electrophile which participates in the reaction. In one embodiment, the aqueous solution is contacted with the electrophile and a phase transfer catalyst and, optionally, a pH adjusting agent in the event that the chemical species in the aqueous solution is not sufficiently ionized to react with the electrophile, and optionally an organic solvent. A method for continuously converting a chemical species involves this contacting step, separating the phases, then dividing the organic phase into the product, the phase transfer catalyst, and the optional organic solvent. |
| FILED | Friday, September 06, 2002 |
| APPL NO | 10/236382 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 558/388 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847060 | Welser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Kopin Corporation (Taunton, Massachusetts) |
| INVENTOR(S) | Roger E. Welser (Providence, Rhode Island); Paul M. Deluca (Providence, Rhode Island); Charles R. Lutz (Seekonk, Massachusetts); Kevin S. Stevens (Providence, Rhode Island) |
| ABSTRACT | A semiconductor material which has a high carbon dopant concentration includes gallium, indium, arsenic and nitrogen. The disclosed semiconductor materials have a low sheet resistivity because of the high carbon dopant concentrations obtained. The material can be the base layer of gallium arsenide-based heterojunction bipolar transistors and can be lattice-matched to gallium arsenide emitter and/or collector layers by controlling concentrations of indium and nitrogen in the base layer. The base layer can have a graded band gap that is formed by changing the flow rates during deposition of III and V additive elements employed to reduce band gap relative to different III-V elements that represent the bulk of the layer. The flow rates of the III and V additive elements maintain an essentially constant doping-mobility product value during deposition and can be regulated to obtain pre-selected base-emitter voltages at junctions within a resulting transistor. |
| FILED | Wednesday, April 10, 2002 |
| APPL NO | 10/121444 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/197 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 06846481 | Gaertig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Jacek Gaertig (Athens, Georgia); Harry W. Dickerson, Jr. (Athens, Georgia); Theodore G. Clark (Ithaca, New York) |
| ABSTRACT | The ciliated protozoan Tetrahymena exemplifies a recombinant system for the expression of heterologous nucleic acids, preferably on the plasma membrane surface. Integration of a heterlogous nucleic acid into the β-tubulin gene, BTU1, of a paclitaxel-sensitive T. thermophila mutant that possesses btu1-1K350M β-tubulin allele allows screening for transformants using negative selection, as transformants have restored paclitaxel resistance. Transgenic ciliated protozoa of the invention can serve as live vaccines. For example, transgenic Tetrahymena expressing Ichthyophthirius multifiliis i-antigen protein on their surface are effective vehicles for vaccination of freshwater fish against infection by I. multifiliis. |
| FILED | Friday, February 04, 2000 |
| APPL NO | 09/498612 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 06846424 | Baum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Technology Materials, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Thomas H. Baum (New Fairfield, Connecticut); Phillip Chen (Bethel, Connecticut); Frank DiMeo, Jr. (Danbury, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut); Peter S. Kirlin (Austin, Texas) |
| ABSTRACT | A process for removing and/or dry etching noble metal-based material structures, e.g., iridium for electrode formation for a microelectronic device. Etch species are provided by plasma formation involving energization of one or more halogenated organic and/or inorganic substance, and the etchant medium including such etch species and oxidizing gas is contacted with the noble metal-based material under etching conditions. The plasma formation and the contacting of the plasma with the noble metal-based material can be carried out in a downstream microwave processing system to provide processing suitable for high-rate fabrication of microelectronic devices and precursor structures in which the noble metal forms an electrode, or other conductive element or feature of the product article. |
| FILED | Tuesday, June 05, 2001 |
| APPL NO | 09/874102 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Etching a substrate: Processes 216/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 06846084 | Grier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | David G. Grier (Chicago, Illinois); Eric R. Dufresne (Arlington, Massachusetts); Jennifer E. Curtis (Chicago, Illinois); Brian A. Koss (Chicago, Illinois) |
| ABSTRACT | A method and apparatus for control of optical trap arrays and formation of particle arrays using light that is in the visible portion of the spectrum. The method and apparatus provides a laser and a time variable diffractive optical element to allow dynamic control of optical trap arrays and consequent control of particle arrays and also the ability to manipulate singular objects using a plurality of optical traps. By avoiding wavelengths associated with strong absorption in the underlying material, creating optical traps with a continuous-wave laser, optimizing the efficiency of individual traps, and trapping extended samples at multiple points, the rate of deleterious nonlinear optical processes can be minimized. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646432 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/614 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Federal Reserve Bank (FED)
| US 06846651 | Fleischmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Human Genome Sciences, Inc. (Rockville, Maryland); Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Robert D. Fleischmann (Gaithersburg, Maryland); Mark D. Adams (Rockville, Maryland); Owen White (Gaithersburg, Maryland); Hamilton O. Smith (Reistertown, Maryland); J. Craig Venter (Queenstown, Maryland) |
| ABSTRACT | The present invention provides the sequencing of the entire genome of Haemophilus influenzae Rd, SEQ ID NO:1. The present invention further provides the sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use. In addition to the entire genomic sequence, the present invention identifies over 1700 protein encoding fragments of the genome and identifies, by position relative to a unique Not I restriction endonuclease site, any regulatory elements which modulate the expression of the protein encoding fragments of the Haemophilus genome. |
| FILED | Monday, June 03, 2002 |
| APPL NO | 10/158865 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 06847619 | Zscheile, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | John Walter Zscheile, Jr. (Rockledge, Florida); Ryan Christopher Reid (Cocoa, Florida); John Schofield Buzby, Jr. (Marina Del Rey, California) |
| ABSTRACT | In a data link communications system there is provided a dual mode of operation multiple access system for communication between a plurality of spoke stations and a central hub station which generates a spoke epoch time comprising a plurality of time division slots in which a spoke station can communicate a priority interrupt request to the central hub station. The spoke epoch time comprises one or more dedicated spoke time slots in which only one hub station may transmit to the hub station to the exclusion of all other spoke stations. The spoke epoch time further comprising one or more priority interrupt request time slots in which all spoke stations can transmit priority interrupt requests to the hub station. Controller means in the hub station provides for evaluating priority interrupt requests from the spoke stations and for granting transmission access to one of said spoke stations during predetermined time slots in the next spoke epoch time. |
| FILED | Friday, May 11, 2001 |
| APPL NO | 09/854104 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 06847839 | Ciaccio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Edward J. Ciaccio (Cherry Hill, New Jersey); Andrew L. Wit (Massapequa, New York); Alexis Christine Tosti (Gladstone, New Jersey) |
| ABSTRACT | A method for identifying and localizing a reentrant circuit isthmus in a heart of a subject during sinus rhythm, including: a) receiving electrogram signals from the heart during sinus rhythm via electrodes; b) storing the electrogram signals; c) creating a map based on the electrogram signals; d) finding a center reference activation location on the map; e) defining measurement vectors originating from the center reference activation location; f) selecting from the measurement vectors a primary axis vector indicating a location of the reentrant circuit isthmus in the heart; g) finding threshold points of electrogram signals on the map; h) connecting the threshold points to form a polygon indicating a shape of the reentrant circuit isthmus in the heart. |
| FILED | Monday, July 30, 2001 |
| APPL NO | 09/918216 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 6/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 06847860 | Mills et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Shane F. Mills (Nichols, New York); Craig R. Peron (Chenango Forks, New York) |
| ABSTRACT | A profiler system is preferably mounted to a conventional roller conveyor frame rail used primarily in mail handling applications. The profiler system contains an array of photo sensors strategically placed to sense the height and length of a mail tray. The sensors are operably connected to a controller that is capable of filtering false signals and accommodating varying conveyor speeds. The controller classifies the object as one of the several types of mail trays or as an unknown object based upon blocked photo sensors. The tray type is reported to a higher-level control system via an industry standard controller communication bus for further processing downstream. |
| FILED | Tuesday, December 11, 2001 |
| APPL NO | 10/014764 |
| ART UNIT | 3653 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 06846842 | Ajami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Beth Israel Deconess Medical Center, Inc. (Boston, Massachusetts); Xanthus Life Sciences, Inc. (Montreal, Canada) |
| INVENTOR(S) | Alfred M. Ajami (Brookline, Massachusetts); Carrie A. Sims (Boston, Massachusetts); Mitchell P. Fink (Pittsburgh, Pennsylvania) |
| ABSTRACT | A therapeutic composition comprising an alkyl, aralkyl, alkoxyalkyl or carboxyalkyl ester of 2-ketoalkanoic acid and a component for inducing and stabilizing the enol resonance form of the ester at physiological pH values is disclosed. The composition of the invention further comprises a pharmceutically acceptable carier vehicle in which the enol resonance form of the ester is stabilized at physiological pH values. Formulations containing the compositions of the invention permit the successful use of 2-ketoalkanoic acid esters, e.g., pyruvic acid esters, to treat, e.g., ischemic events, shock, organ reanimation, resuscitation and other recognized pyruvate-effective treatments. The compositions of the inventions are also useful in a process for preserving organ parts, organs or limbs removed from a living mammal and in need of preservation, e.g., for later transplantation to an organ recipient. |
| FILED | Thursday, April 04, 2002 |
| APPL NO | 10/116707 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/547 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06847456 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Changhuei Yang (Cambridge, Massachusetts); Adam P. Wax (Boston, Massachusetts); Lev T. Perelman (Brookline, Massachusetts); Ramachandra R. Dasari (Lexington, Massachusetts); Michael S. Feld (Newton, Massachusetts) |
| ABSTRACT | The present invention relates to systems and methods of field-based light scattering spectroscopy. These systems and methods provide for the diagnosis of tissue by measuring the size and distribution of cellular characteristics. Field based measurements provide phase information resulting from the interaction of scatterers within the material and the incident wavefront. These measurements can be used to provide three dimensional images of tissue. |
| FILED | Friday, April 27, 2001 |
| APPL NO | 09/844286 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 25, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050125.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page