FedInvent™ Patents
Patent Details for Tuesday, February 08, 2005
This page was updated on Sunday, March 26, 2023 at 07:44 PM GMT
Department of Health and Human Services (HHS)
| US 06852308 | Kohn et al. |
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| ASSIGNEE(S) | Rutgers, The State University (New Brunswick, New Jersey) |
| INVENTOR(S) | Joachim B. Kohn (Highland Park, New Jersey); Durgadas Bolikal (Edison, New Jersey); Sanyog M. Pendharkar (Old Bridge, New Jersey) |
| ABSTRACT | Iodinated and/or brominated derivatives of aromatic dihydroxy monomers are prepared and polymerized to form radio-opaque polymers. The monomers may also be copolymerized with other dihydroxy monomers. The iodinated and brominated aromatic dihydroxy monomers can be employed as radio-opacifying, biocompatible non-toxic additives for other polymeric biomaterials. Radio-opaque medical implants and drug delivery devices for implantation prepared from the polymers of the present invention are also disclosed. |
| FILED | Tuesday, November 05, 2002 |
| APPL NO | 10/288076 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852318 | Varner |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judith A. Varner (Encinitas, California) |
| ABSTRACT | The present invention provides methods for reducing or inhibiting angiogenesis in a tissue, by contacting α5β1 integrin in the tissue with an agent that interferes with specific binding of the α5β1 integrin to a ligand expressed in the tissue; and methods of identifying angiogenesis in a tissue, by contacting the tissue with an agent that specifically binds α5β1 integrin, and detecting specific binding of the agent to α5β1 integrin associated with a blood vessel in the tissue. Also provided are methods of diagnosing a pathological condition characterized by angiogenesis in a tissue in an individual. The invention further provides methods of reducing or inhibiting angiogenesis in a tissue in an individual, by administering to the individual an agent that interferes with the specific binding of α5β1 integrin to a ligand expressed in the tissue; and methods of reducing the severity of a pathological condition associated with angiogenesis in an individual, by administering to the individual an agent that interferes with specific binding of α5β1 integrin to a ligand in a tissue associated with the pathological condition. The invention also provides methods of identifying an agent that reduces or inhibits angiogenesis associated with α5β1 integrin expression in a tissue by contacting a tissue exhibiting angiogenesis associated with α5β1 integrin expression with an agent, and detecting a reduction or inhibition of angiogenesis in the tissue. |
| FILED | Friday, May 07, 1999 |
| APPL NO | 09/307223 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852319 | Hein et al. |
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| ASSIGNEE(S) | The Scripps Research Institue (La Jolla, California) |
| INVENTOR(S) | Mich B. Hein (Fallbrook, California); Andrew Hiatt (San Diego, California); Julian K-C Ma (London, United Kingdom) |
| ABSTRACT | The present invention relates to expression and assembly of foreign multimeric proteins—e.g., antibodies—in plants, as well as to transgenic plants that express such proteins. In one of several preferred embodiments, the generation and assembly of functional secretory antibodies in plants is disclosed. The invention also discloses compositions produced by the transgenic plants of the present invention and methods of using same. |
| FILED | Tuesday, January 25, 2000 |
| APPL NO | 09/491322 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/132.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852320 | Blumberg |
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| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Richard S. Blumberg (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention relates to compositions which bind T cell inhibitory receptor molecules and modulate T cell activity, and methods of using such compositions. Such compositions include biliary glycoprotein binding agents. Methods for modulating killer T cell activities, including cytotoxicity and proliferation also are provided. |
| FILED | Tuesday, June 19, 2001 |
| APPL NO | 09/884196 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852323 | Lue et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tom F. Lue (Hillsborough, California); Ching-Shwun Lin (San Mateo, California); Yuet W. Kan (San Francisco, California) |
| ABSTRACT | This invention relates generally to the field of urology. In particular, the invention provides a method for preventing or treating male erectile dysfunction or female sexual arousal disorder, which method comprises administering an effective amount of vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), basic fibroblast growth factor (bFGF), or a functional derivative or fragment thereof, or a nucleic acid encoding said VEGF, BDNF or bFGF, or functional derivative or fragment thereof, or an agent that enhances production and/or erection or sexual arousal stimulating function of said VEGF or BDNF or bFGF to a mammal, wherein such prevention or treatment is desirable, thereby preventing or treating said male erectile dysfunction or female sexual arousal disorder in said mammal. Combinations, combinatorial methods and kits for preventing or treating male erectile dysfunction or female sexual arousal disorder are also provided. |
| FILED | Thursday, July 19, 2001 |
| APPL NO | 09/909544 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/198.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852324 | Nabel et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Gary J. Nabel (Washington, District of Columbia); Anthony Sanchez (Atlanta, Georgia) |
| ABSTRACT | Ebola virus vaccines comprising nucleic acid molecules encoding Ebola viral proteins are provided. In one embodiment, the nucleic acid molecule encodes the transmembrane form of the viral glycoprotein (GP). In another embodiment, the nucleic acid molecule encodes the secreted form of the viral glycoprotein (sGP). In yet another embodiment, the nucleic acid molecule encodes the viral nucleoprotein (NP). Methods for immunizing a subject against disease caused by infection with Ebola virus are also provided. |
| FILED | Wednesday, December 23, 1998 |
| APPL NO | 09/913909 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852339 | Spievack |
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| ASSIGNEE(S) | ACell, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Alan R. Spievack (Cambridge, Massachusetts) |
| ABSTRACT | A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate. |
| FILED | Friday, October 25, 2002 |
| APPL NO | 10/280802 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/551 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852416 | Zhang et al. |
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| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Qiming Zhang (State College, Pennsylvania); Zhongyang Cheng (State College, Pennsylvania); Haisheng Xu (Linköping, Sweden) |
| ABSTRACT | There are disclosed new composite materials having improved electric field induced strain levels, improved electric constants, and having advantageous mechanical properties for use in electrical devices. |
| FILED | Friday, April 12, 2002 |
| APPL NO | 10/121936 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/421 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852487 | Barany et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Francis Barany (New York, New York); George Barany (Falcon Heights, Minnesota); Robert P. Hammer (Baton Rouge, Louisiana); Maria Kempe (Minneapolis, Minnesota); Herman Blok (Wemeldinge, Netherlands); Monib Zirvi (New York, New York) |
| ABSTRACT | The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detection phase. The ligation phase utilizes a ligation detection reaction between one oligonucleotide probe, which has a target sequence-specific portion and an addressable array-specific portion, and a second oligonucleotide probe, having a target sequence-specific portion and a detectable label. After the ligation phase, the capture phase is carried out by hybridizing the ligated oligonucleotide probes to a solid support with an array of immobilized capture oligonucleotides at least some of which are complementary to the addressable array-specific portion. Following completion of the capture phase, a detection phase is carried out to detect the labels of ligated oligonucleotide probes hybridized to the solid support. The ligation phase can be preceded by an amplification process. The present invention also relates to a kit for practicing this method, a method of forming arrays on solid supports, and the supports themselves. |
| FILED | Tuesday, February 04, 1997 |
| APPL NO | 08/794851 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852488 | Fodor et al. |
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| ASSIGNEE(S) | Affymetrix, Inc. (Santa Clara, California) |
| INVENTOR(S) | Stephen P. A. Fodor (Palo Alto, California); Robert J. Lipshutz (Palo Alto, California); Xiaohua Huang (Mt. View, California) |
| ABSTRACT | Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques. |
| FILED | Tuesday, February 06, 2001 |
| APPL NO | 09/776768 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852490 | Gentalen et al. |
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| ASSIGNEE(S) | Affymetrix, Inc. (Santa Clara, California) |
| INVENTOR(S) | Erik Gentalen (Redwood City, California); Mark Chee (Del Mar, California) |
| ABSTRACT | The invention provides arrays of polynucleotide probes having at least one pooled position. A typical array comprises a support having at least three discrete regions. A first region bears a pool of polynucleotide probes comprising first and second probes. A second region bears the first probe without the second probe and a third region bears the second probe without the first probe. A target nucleic acid having segments complementary to both the first and second probes shows stronger normalized binding to the first region than to the aggregate of binding to the second and third regions due to cooperative binding of pooled probes in the first region. The invention provide methods of using such arrays for e.g., linkage analysis, sequence analysis, and expression monitoring. |
| FILED | Tuesday, August 14, 2001 |
| APPL NO | 09/930536 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852514 | Weigel et al. |
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| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Paul H. Weigel (League City, Texas); Paul L. DeAngelis (Galveston, Texas); John Papaconstantinou (Galveston, Texas) |
| ABSTRACT | Disclosed are DNA sequences encoding hyaluronic acid synthase that are employed to construct recombinant cells useful in the production of hyaluronate synthase and hyaluronic acid (HA). In preferred aspects, chromosomal DNA encoding the HA synthase gene, hasA, was cloned from a Streptococcus pyogenes genomic library. These vectors were used to transform host cells such as E. coli and acapsular Streptococci to produce hyaluronic acid. Resultant transformants were screened to identify colonies which have incorporated HA synthase DNA in a form that is being actively transcribed into the corresponding HA synthase enzyme. These colonies were selected and employed in the production of hyaluronic acid. |
| FILED | Wednesday, April 03, 2002 |
| APPL NO | 10/117795 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/84 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852518 | Rosen et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Syntex (U.S.A.) LLC (Palo Alto, California) |
| INVENTOR(S) | Steven D. Rosen (San Francisco, California); Jin Kyu Lee (Alameda, California); Stefan Hemmerich (Berkeley, California) |
| ABSTRACT | Novel glycosylsulfotransferases (GST-4α, GST-4β, and GST-6) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including various diagnostic and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-4α, GST-4β, and GST-6. |
| FILED | Tuesday, June 13, 2000 |
| APPL NO | 09/593828 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852522 | Palese et al. |
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| ASSIGNEE(S) | Mount Sinai School of Medicine of New York University (New York, New York) |
| INVENTOR(S) | Peter Palese (Leonia, New Jersey); Adolfo Garcia-Sastre (New York, New York); Robert O'Neil (New York, New York) |
| ABSTRACT | The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations. |
| FILED | Tuesday, November 28, 2000 |
| APPL NO | 09/724419 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/239 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852525 | Cantor |
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| ASSIGNEE(S) | Advanced Sensor Technologies (Farmington Hills, Michigan) |
| INVENTOR(S) | Hal C. Cantor (Farmington Hills, Michigan) |
| ABSTRACT | The present invention relates to a cell culture chamber (10) having a sterile environment (12) for the culture of cells, a cover (14) for allowing for a transfer of pits and a sensor array. |
| FILED | Saturday, November 02, 2002 |
| APPL NO | 10/129248 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852530 | Silver et al. |
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| ASSIGNEE(S) | Dana Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Daniel P. Silver (Wayland, Massachusetts); David M. Livingston (Brookline, Massachusetts) |
| ABSTRACT | Nucleic acid molecules comprising at least a first signal site and a recombinase gene operably linked to an expression control sequence, such that upon entry into a cell, there is a first signal site and a second signal site positioned to mediate excision of a sufficient portion of either the recombinase gene or the expression control sequence to extinguish recombinase activity when the first and second signal sites are contacted with a recombinase, cells, transgenics and uses of the foregoing. |
| FILED | Thursday, April 12, 2001 |
| APPL NO | 09/834778 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852537 | Hebbel et al. |
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| ASSIGNEE(S) | Regents of the University of Minnesota Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Robert P. Hebbel (North Oaks, Minnesota); Yi Lin (St. Paul, Minnesota); John S. Lollar (Decatur, Georgia) |
| ABSTRACT | A process is provided for expanding the population of endothelial cells obtained from peripheral blood which can be transformed with a vector comprising a DNA sequence encoding a preselected bioactive polypeptide. The resulting transgenic endothelial cells are useful to biocompatibilize implantable medical devices or can be used directly, as for gene therapy. |
| FILED | Thursday, May 24, 2001 |
| APPL NO | 09/865022 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852538 | Drouin et al. |
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| ASSIGNEE(S) | Institut de Recherches Cliniques de Montreal (Montreal, Canada) |
| INVENTOR(S) | Jacques Drouin (Outremont, Canada); Alexandra Philips (Sete, Canada); Mario Maira (Montreal, Canada) |
| ABSTRACT | The present invention relates to intracellular receptors, and methods for the modulation of transcription using same. More particularly, the invention relates to the Nur family of nuclear receptors. In general aspects, the present invention relates to the idenfication of a physiologically relevant response element (RE) for Nur family members, an ER-10 element as well as to the idenfication of the type of protein-protein interactions of Nur family member, enabling their specific interaction with this RE-10 and tfeir modulation of transcription at physiologically relevant sites. The invention further relates to methods for modulating processes mediated by such nuclear receptors. In addition, the invention relates to oligonucleotide sequences that bind regulatory proteins that affect transcription, such as the Nur family of nuclear receptors, to DNA constructs comprising the oligonucleotide sequences, cells transfected with the DNA constructs, to methods of using same to provide for the controlled expression of heterologous genes, and for the detection and recovery of new regulatory proteins. The present invention further provides bioassays for the identification of compounds as potential agonists or antagonists of transcription by the Nur family of nuclear receptors Moreover, the invention relates to the dissection of protein-protein interactions or ligand-protein interactions involved in the modulation of transcription by the Nur family of nuclear receptors. |
| FILED | Friday, December 12, 1997 |
| APPL NO | 09/319782 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852544 | Aebersold et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Rudolf Hans Aebersold (Mercer Island, Washington); Michael H. Gelb (Seattle, Washington); Steven P. Gygi (Seattle, Washington); C. Ronald Scott (Seattle, Washington); Frantisek Turecek (Seattle, Washington); Scott A. Gerber (Seattle, Washington); Beate Rist (Seattle, Washington) |
| ABSTRACT | Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques. The reagents also provide for differential isotopic labeling of the isolated peptides or reaction products which facilitates quantitative determination by mass spectrometry of the relative amounts of proteins in different samples. The methods of this invention can be used for qualitative and quantitative analysis of global protein expression profiles in cells and tissues, to screen for and identify proteins whose expression level in cells, tissue or biological fluids is affected by a stimulus or by a change in condition or state of the cell, tissue or organism from which the sample originated. |
| FILED | Friday, April 20, 2001 |
| APPL NO | 09/839884 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852686 | Steinert et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Peter Steinert (Bethesda, Maryland); Lyuben Marekov (Rockville, Maryland); Zoltan Nemes (Debrecen, Hungary) |
| ABSTRACT | The present invention relates to the discovery of a method to provide stabilized transglutaminase 1 enzyme, involucrin, and other molecules necessary for the assembly of the cell envelope to skin cells. Novel biological tools, prophylactics, therapeutics, cosmetics, and methods of use of the foregoing for study, prevention, and treatment of skin disorders are also disclosed. |
| FILED | Thursday, December 13, 2001 |
| APPL NO | 10/023275 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852696 | Takashima et al. |
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| ASSIGNEE(S) | The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Akira Takashima (Coppel, Texas); Mark E. Mummert (Dallas, Texas) |
| ABSTRACT | The present invention provides peptide derivatives with a specific affinity for glycosaminoglycan molecules. These peptide derivatives include multimers as well as chemically modified peptides and may be prepared by a variety of methods. The peptides of the invention have numerous functions, including but not limited to use as inhibitors of glycosaminoglycan-mediated signaling events and targeting agents. Peptides of the invention may be directed against any glycosaminoglycan, including hyaluronic acid, chondroitin sulfate A, chondroitin sulfate C, dermatan sulfate, heparin, keratan sulfate, keratosulfate, chitin, chitosan 1, and chitosan 2. The peptide derivatives of the invention also have therapeutic uses in the treatment and prevention of diseases involving inflammatory diseases, cancer, and cancer metastasis, autoimmune diseases, etc. |
| FILED | Wednesday, March 20, 2002 |
| APPL NO | 10/105774 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852704 | Levy et al. |
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| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert J. Levy (Merion Station, Pennsylvania); Scott Baldwin (West Chester, Pennsylvania) |
| ABSTRACT | The invention relates to compositions and methods for reverse gene therapy, wherein a gene therapy vector encoding a gene product (e.g. a protein) which is usually only expressed in cells of an abnormal tissue is delivered to a cell of an animal afflicted with a disease or disorder to alleviate the disease or disorder. In one embodiment, a plasmid vector encoding HERG (A561V) protein is delivered to a cell of an animal afflicted with re-entrant atrial flutter-mediated cardiac arrhythmia. |
| FILED | Wednesday, January 19, 2000 |
| APPL NO | 09/487851 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852709 | Leong et al. |
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| ASSIGNEE(S) | Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Kam Leong (Ellicott City, Maryland); Wen Jie (Baltimore, Maryland); Hai-Quan Mao (Coast Crescent, Singapore) |
| ABSTRACT | The present invention provides biodegradable polymers, polymer compositions, particles composed thereof and methods of using same for the controlled release of a biologically active substance to a specified tissue or cells. Preferred polymers include biodegradable, amphiphilic polyphosphates which are capable of complexing one or more biologically active substances. Preferred methods include the controlled release of biologically active substances and gene therapy using polymers and nanoparticles composed thereof. |
| FILED | Thursday, May 31, 2001 |
| APPL NO | 09/871602 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/75 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852741 | Papke |
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| ASSIGNEE(S) | University of Florida (Gainesville, Florida) |
| INVENTOR(S) | Roger L. Papke (Gainesville, Florida) |
| ABSTRACT | The present invention concerns methods for treating or preventing neurological disorders characterized by dysfunction of nicotinic acetylcholine receptors by co-administration of metanicotine and at least one compound which exhibits antagonist activity, or both agonistic and antagonists activity, toward one or more nicotinic acetylcholine receptor subtypes. The subject invention, in another aspect, pertains to pharmaceutical compositions containing metanicotine and at least one compound which inhibits antagonistic activity, or both agonistic and antagonistic activity, toward one or more nicotinic acetylcholine receptor subtypes. |
| FILED | Monday, December 31, 2001 |
| APPL NO | 10/036988 |
| ART UNIT | 1614 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852832 | Kowalczykowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stephen C. Kowalczykowski (Davis, California); Frédéric Chédin (Arcadia, California); Erica M. Seitz (Davis, California) |
| ABSTRACT | The invention provides ssDNA-binding proteins from three species of archaeons, Methanococcus jannaschii, Methanobacter theromoautotrophicum, and Archaeoglobus fulgidus, as well as the ability to identify ssDNA-binding proteins from other archaeons. The proteins help render DNA more accessible to DNA polymerase and are robust reagents for a variety of biotechnical processes, including PCR. The invention further provides nucleic acids encoding such proteins, vectors for transfecting host cells, host cells comprising the vectors, and methods of using the proteins. |
| FILED | Friday, August 04, 2000 |
| APPL NO | 09/631616 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852842 | Brechbiel et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Martin W. Brechbiel (Annandale, Virginia); Robert A. Star (Bethesda, Maryland); Hisataka Kobayashi (Nishinomiya, Japan) |
| ABSTRACT | Small dendrimer-based MRI contrast agents are disclosed to accumulate in renal tubules. The accumulation enables visualization of renal structure and function, permitting assessment of structural and functional damage to the kidneys. In a disclosed embodiment, six, small dendrimer-based MRI contrast agents were synthesized, and their pharmacokinetics, whole body retention, and renal MRI images were evaluated in mice. Surprisingly, despite having unequal renal clearance properties, all of the dendrimer agents clearly visualized the renal anatomy and proximal straight tubules of the mice better than Gd-[DTPA]-dimeglumine. Dendrimer conjugate contrast agents prepared from PAMAM-G2D, DAB-G3D, and DAB-G2D dendrimers were excreted rapidly and may be acceptable for use in clinical applications. |
| FILED | Monday, August 26, 2002 |
| APPL NO | 10/229316 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Organic compounds 534/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852849 | Tsien et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Robert E. Campbell (San Diego, California) |
| ABSTRACT | Non-oligomerizing fluorescent proteins, which are formed by operatively linking two or more monomers of a fluorescent protein, or which are derived from a fluorescent protein having at least one mutation that reduces or eliminates the ability of the fluorescent protein to oligomerize, are provided. The non-oligomerizing fluorescent proteins can be derived from a naturally occurring green fluorescent protein, a red fluorescent protein, or other fluorescent protein, or a fluorescent protein related thereto. Also provided is a fusion protein, which includes a non-oligomerizing fluorescent protein linked to at least one polypeptide of interest. In addition, a polynucleotide encoding a non-oligomerizing fluorescent protein is provided, as is a recombinant nucleic acid molecule, which includes polynucleotide encoding a non-oligomerizing fluorescent protein operatively linked to at least a second polynucleotide. Vectors and host cells containing such polynucleotides also are provided, as are kits containing one or more non-oligomerizing fluorescent proteins or encoding polynucleotides or constructs derived therefrom. Further provided are methods of making and using the proteins and polynucleotides. |
| FILED | Thursday, May 24, 2001 |
| APPL NO | 09/866538 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852874 | Sharpless et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | K. Barry Sharpless (La Jolla, California); Malin Andersson (Gothenburg, Sweden); Robert Epple (La Jolla, California); Valery Fokin (Carlsbad, California) |
| ABSTRACT | A process for catalyzing asymmetric dihydroxylations of olefins employs an Os(VI) complex as a catalytic intermediate in the formation of chiral vicinal diol products. The process requires a chiral bidentate ligand that favors diol formation in the “second cycle” of asymmetric dihydroxylation. |
| FILED | Tuesday, August 28, 2001 |
| APPL NO | 09/941410 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 560/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853191 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of The Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Karla L. Miller (San Francisco, California); John M. Pauly (Redwood City, California) |
| ABSTRACT | Disclosed is a generalized reconstruction method that corrects for non-linear phase errors based on least-squares estimation. An approximation of the least squares estimate utilizes refocusing reconstruction in which high-resolution data is multiplied by the phase conjugate of a navigator in image-space. The multiplication rephases the unaliased signal in the high-resolution data. The high-resolution data can then be added together coherently. The multiplication can be effected in k-space as a convolution using a gridding reconstruction of the high-resolution data using the low resolution navigator. |
| FILED | Wednesday, December 10, 2003 |
| APPL NO | 10/733011 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853193 | Riederer et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Stephen J. Riederer (Rochester, Minnesota); David G. Kruger (Nelson, Wisconsin); Phillip J. Rossman (Rochester, Minnesota) |
| ABSTRACT | A method for the simultaneous acquisition of data from two transmit/receive “birdcage” coils is described. The coils are individually RF shielded, making them insensitive to signals generated outside of each coil's volume. Each coil is designed for imaging one leg, and when used together, both legs are imaged simultaneously. In coronal or axial orientations, a small FOV around each leg can be imaged without aliasing. This results in a two-fold scan time reduction compared to a large FOV acquisition with the same spatial resolution. |
| FILED | Thursday, May 08, 2003 |
| APPL NO | 10/431935 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/318 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 06851259 | Simburger et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Edward J. Simburger (Agoura, California); Henry Helvajian (Pasadena, California) |
| ABSTRACT | An inflatable structure includes a plurality of inflation cells each have a respective internal gas generator connected to an external control processor for sequential inflation of the inflatable structure. Power and control lines feed through the inflation cells for powering the internal gas generator and for communicating control signals between the gas generators and the external control processor. A method of sequence inflation can use various types of exemplar gas generators, such as cellular containment evaporation gas generators and laser ablation gas generators. |
| FILED | Wednesday, June 12, 2002 |
| APPL NO | 10/171715 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/409 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06851263 | Stumpf et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | James Anthony Stumpf (Milford, Ohio); Beverly Stephenson Duncan (West Chester, Ohio); David Louis Burrus (Cincinnati, Ohio); Clayton Stuart Cooper (Loveland, Ohio) |
| ABSTRACT | A liner for a gas turbine engine combustor having a trapped vortex cavity formed therein, wherein a dome plate is positioned at an upstream end of the combustor, includes: a first portion positioned adjacent and connected to the dome plate, wherein the first liner portion extends downstream from and substantially perpendicular to the dome plate; a second portion extending substantially perpendicular to the first liner portion and substantially parallel to the dome plate; a first arcuate portion having a predetermined radius located between the first and second liner portions; a third portion extending downstream and substantially perpendicular to the second liner portion; and, a second arcuate portion located between the second and third liner portions; wherein the first liner portion, the second liner portion, the first arcuate liner portion and a portion of the dome plate form the trapped vortex cavity. |
| FILED | Tuesday, October 29, 2002 |
| APPL NO | 10/282520 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/750 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06851347 | Plunkett |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stephen J. Plunkett (Middletown, Rhode Island) |
| ABSTRACT | A launch capsule assembly having a buoyant main body for a payload of a missile or other unmanned vehicle. The main body includes a plurality of lobes contributing to its interior. The lobes project perpendicular to and away from the longitudinal axis of the main body with the interior of each projecting lobe sized to accommodate at least one projecting fin of the payload. The top of the main body removably attaches to a top cap projecting hydrodynamically from the main body. The bottom of the main body removably attaches to a bottom cap machined to have a matching cross-section to the main body of the capsule. |
| FILED | Thursday, June 05, 2003 |
| APPL NO | 10/456245 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/1.810 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06851381 | Pruitt et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas Pruitt (Panama City, Florida); Daniel Georgiadis (Panama City, Florida); Joseph Papciak (Lynn Haven, Florida) |
| ABSTRACT | A combination pressure relief valve system and undersea vehicle vents pressurized gas from lithium batteries to ambient. An undersea vehicle having an interior has a pair of hollow pylons each having a passageway fluidly communicating with the interior. A pressure relief valve is mounted on each pylon, and each pressure relief valve has a body portion having an inner bore fluidly communicating with a passageway. An elongate valve plug in the body portion is interposed between each passageway and ambient and the valve plug has a lateral bore and a circumferentially disposed O-ring. A nose portion is secured to the body portion, and the nose portion has a pair of laterally aligned bores aligned with the lateral bore of the elongate valve plug. A wire extends through the laterally aligned bores and lateral bore. The O-ring and wire retain the valve plug interposed between a passageway and ambient. |
| FILED | Tuesday, March 25, 2003 |
| APPL NO | 10/402903 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/331 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06851724 | Pittman, II |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | John Edward Pittman, II (Ashland, Massachusetts) |
| ABSTRACT | A dual flow rotating union with a longitudinal axis, including a conduit having opposing ports oriented parallel to the longitudinal axis, the conduit having a rotating section and a stationary section. One conduit port is located on the rotating section, the other conduit port is located on the stationary section. A housing is disposed about the conduit, the housing also having opposing ports oriented parallel to the longitudinal axis. The housing includes a stator portion and a rotor portion rotatably disposed with respect to the stator portion. One housing port is located on the stator portion and the other housing port is located on the rotor portion. |
| FILED | Thursday, June 20, 2002 |
| APPL NO | 10/175761 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipe joints or couplings 285/275 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06851938 | Ding et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Yuqing Ding (Baltimore, Maryland); M. Douglas Levan (Brentwood, Tennessee) |
| ABSTRACT | A magnetic pumping system includes a pump, capable of urging a fluid therefrom during a forward stroke and a return stroke, having a piston disposed within a cylinder defined by a pump body, and a driver disposed external to the pump body. The driver is capable of moving the piston by a magnetic field interaction between the driver and the piston. The system further includes a check valve bridge, spaced away from the pump and in fluid communication with the cylinder, capable of allowing ingress and egress of the fluid into and out of the cylinder in response to a movement by the piston. |
| FILED | Tuesday, August 27, 2002 |
| APPL NO | 10/228438 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Pumps 417/418 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852160 | Sambasivan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Applied Thin Films, Inc. (Evanston, Illinois) |
| INVENTOR(S) | Sankar Sambasivan (Chicago, Illinois); Scott A. Barnett (Evanston, Illinois); Ilwon Kim (Skokie, Illinois); John Rechner (Wilmette, Illinois) |
| ABSTRACT | The present invention relates to oxides on suitable substrates, as converted from nitride precursors. |
| FILED | Tuesday, June 03, 2003 |
| APPL NO | 10/453470 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/90 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852171 | Downs |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | Stuart G. Downs (San Diego, California) |
| ABSTRACT | Deicing of an external mirror (10) on a vehicle is effected by applying a sudden deformation force to the mirror. Sandwiched between the mirror (10) and a mounting surface (12) is a structure that includes a ribbon conductor (14), portions of which overlap each other in such a way that current through the conductor passes through these portions in opposite directions. A capacitor (32) is discharged through the conductor (14), generating a magnetic field that results in mutual repulsion between the overlapping portions. The mounting surface resists this repulsion force, which is instead transferred to the mirror (10), causing momentary distortion, and dislodgment of ice on the mirror surface. The same technique is also applicable to deicing of windows. |
| FILED | Wednesday, May 15, 2002 |
| APPL NO | 10/146260 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Cleaning and liquid contact with solids 134/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852182 | Adolph et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Horst G. Adolph (Warrenton, Virginia); Michael E. Sitzmann (Adelphi, Maryland) |
| ABSTRACT | A degradable prepolymer for explosive and propellant compositions having increased hydrolyzability comprising at one —O—CH2—O— linkage within the backbone of the prepolymer. The degradable prepolymer is useful as a binder for explosive and propellant compositions. |
| FILED | Wednesday, May 09, 2001 |
| APPL NO | 09/853927 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive and thermic compositions or charges 149/19.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852248 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Shin-Tson Wu (Northridge, California); Seth Marder (Tuscon, Arizona); Qing T. Zhang (Dallas, Texas) |
| ABSTRACT | High-dielectric colorless or virtually colorless dopants for low-voltage and tunable clearing temperature liquid-crystal devices. These dopant compounds help reduce the operation voltage for both polar and non-polar liquid-crystal (LC) mixtures. Methods for making and using these dopant compounds are also disclosed. |
| FILED | Friday, April 02, 1999 |
| APPL NO | 09/285937 |
| ART UNIT | 1756 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/299.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852272 | Artz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Ceramics Research, Inc. (Tucson, Arizona) |
| INVENTOR(S) | Gregory Artz (Tucson, Arizona); K. Ranji Vaidyanathan (Tucson, Arizona); Michael L. Fulcher (Tucson, Arizona); Mark J. Rigali (Tucson, Arizona); John L. Lombardi (Tucson, Arizona); Joseph Walish (Miami, Arizona); Ronald A. Cipriani (Tucson, Arizona) |
| ABSTRACT | The present invention relates to the fabrication of low cost, in situ, porous metallic, ceramic and cermet foam structures having improved mechanical properties such as energy absorption and specific stiffness. Methods of fabricating the structures from compositions including ceramic and/or metallic powders are provided. The flowable compositions also include an immiscible phase that results in pores within the final structure. Furthermore, the structures may be shaped to have external porosity, such as with mesh-like structures. |
| FILED | Monday, January 27, 2003 |
| APPL NO | 10/351693 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Powder metallurgy processes 419/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852285 | Abbott et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Justin J. Skaife (Lafayette, California); Vinay K. Gupta (Urbana, Illinois); Timothy B. Dubrovsky (Flemington, New Jersey); Rahul Shah (Davis, California) |
| ABSTRACT | Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction. |
| FILED | Tuesday, July 03, 2001 |
| APPL NO | 09/898132 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852395 | Dhawan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Anuj Dhawan (Raleigh, North Carolina); Tushar Kanti Ghosh (Raleigh, North Carolina); John Muth (Raleigh, North Carolina); Abdelfattah Seyam (Cary, North Carolina) |
| ABSTRACT | Methods and systems for selectively connecting and disconnecting conductors in a fabric are disclosed. First and second conductors are integrated into a fabric such that the conductors intersect at a crossover point. The conductors are bonded to each other at the crossover point to improve AC and DC characteristics. Disconnect areas may be provided near the crossover point to allow selective disconnection of the conductors from the crossover point. |
| FILED | Tuesday, January 08, 2002 |
| APPL NO | 10/041248 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/196 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852410 | Veedu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Sreekumar T. Veedu (Atlanta, Georgia); Satish Kumar (Lawrenceville, Georgia) |
| ABSTRACT | The present invention relates to a high modulus macroscopic fiber comprising single-wall carbon nanotubes (SWNT) and an acrylonitrile-containing polymer. In one embodiment, the macroscopic fiber is a drawn fiber having a cross-sectional dimension of at least 1 micron. In another embodiment, the acrylonitrile polymer-SWNT composite fiber is made by dispersing SWNT in a solvent, such as dimethyl formamide or dimethyl acetamide, admixing an acrylonitrile-based polymer to form a generally optically homogeneous polyacrylonitrile polymer-SWNT dope, spinning the dope into a fiber, drawing and drying the fiber. Polyacrylonitrile/SWNT composite macroscopic fibers have substantially higher modulus and reduced shrinkage versus a polymer fiber without SWNT. A polyacrylonitrile/SWNT fiber containing 10 wt % SWNT showed over 100% increase in tensile modulus and significantly reduced thermal shrinkage compared to a control fiber without SWNT. With 10 wt % SWNT, the glass transition temperature of the polymer increased by more than 40° C. |
| FILED | Monday, June 30, 2003 |
| APPL NO | 10/609724 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852416 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Qiming Zhang (State College, Pennsylvania); Zhongyang Cheng (State College, Pennsylvania); Haisheng Xu (Linköping, Sweden) |
| ABSTRACT | There are disclosed new composite materials having improved electric field induced strain levels, improved electric constants, and having advantageous mechanical properties for use in electrical devices. |
| FILED | Friday, April 12, 2002 |
| APPL NO | 10/121936 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/421 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852446 | Barbarich |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Yardney Technical Products, Inc. (Pawcatuck, Connecticut) |
| INVENTOR(S) | Thomas J. Barbarich (Westerly, Rhode Island) |
| ABSTRACT | A non-aqueous electric current producing electrochemical cell is provided comprising an anode and a cathode, an ionically permeable separator interposed between the anode and the cathode, and a non-aqueous electrolyte, the electrolyte comprising an ionically conducting salt in a non-aqueous medium, the ionically conducting salt corresponding to the formula: M+(Z*(J*)j(X*)x)−, wherein: M is a lithium atom, Z* is an anion group containing two or more Lewis basic sites and comprising less than 50 atoms not including hydrogen atoms, J* independently each occurance is a Lewis acid coordinated to at least one Lewis basic site of Z*, and optionally two or more such J* groups may be joined together in a moiety having multiple Lewis acidic functionality, X* independently each occurrence is selected from the group consisting of H, C1-C4 alkyl, alkoxide, halide and mixtures thereof, j is an integer from 2 to 12, and x is an integer from 0 to 4. |
| FILED | Thursday, November 07, 2002 |
| APPL NO | 10/289784 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852593 | Basceri et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Cem Basceri (Boise, Idaho); Gurtej Sandhu (Boise, Idaho) |
| ABSTRACT | Described herein is a method for producing a haze-free (Ba, Sr)TiO3 (BST) film, and devices incorporating the same. In one embodiment, the BST film is made haze-free by depositing the film with a substantially uniform desired crystal orientation, for example, (100), preferably by forming the film by metal-organic chemical vapor deposition at a temperature greater than about 580° C. at a rate of less than about 80 Å/min, to result in a film having about 50 to 53.5 atomic percent titanium. In another embodiment, where the BST film serves as a capacitor for a DRAM memory cell, a desired {100} orientation is induced by depositing the bottom electrode over a nucleation layer of NiO, which gives the bottom electrode a preferential {100} orientation. BST is then grown over the {100} oriented bottom electrode also with a {100} orientation. A nucleation layer of materials such as Ti, Nb and Mn can also be provided over the bottom electrode and beneath the BST film to induce smooth, haze-free BST growth. Haze-free BST film can also be favored by forming the bottom electrode at high temperatures close to those used for BST deposition, and without a vacuum break between the bottom electrode and BST deposition. |
| FILED | Thursday, July 03, 2003 |
| APPL NO | 10/614489 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/253 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852891 | Murray et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | George M. Murray (Columbia, Maryland); Craig A. Kelly (Ellicott City, Maryland); O. Manuel Uy (Ellicott City, Maryland); Lawrence W. Hunter (Ellicott City, Maryland); David S. Lawrence (Ellicott City, Maryland) |
| ABSTRACT | A method of inhibiting or preventing the use of anhydrous ammonia as a solvent in a dissolving metal reduction process comprises adding to anhydrous ammonia a chemical reagent which is capable of scavenging solvated electrons generated when alkali or alkaline earth metal is dissolved in the anhydrous ammonia, the chemical reagent being added to the anhydrous ammonia such that when alkali metal is dissolved in the anhydrous ammonia containing the chemical reagent and thereafter ephedrine, pseudoephedrine or combination thereof is introduced to the anhydrous ammonia to produce a reaction product, the methamphetamine yield in the reaction product is below 50%, preferably below 10%, and more preferably below 1%. Preferred chemical reagents include Fe(III)citrate, ferrocene, 2-chloro-6-(trichloromethyl)pyridine and 1,1,1,2-tetrafluoroethane. |
| FILED | Thursday, June 21, 2001 |
| APPL NO | 10/297626 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/381 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852903 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Roy S. Brown (Worthington, Ohio); Joseph A. Rossin (Columbus, Ohio); James E. Kotary (Columbus, Ohio); Gyleen Fitzgerald (Churchville, Maryland); Karl G. Gerhart (Aberdeen, Maryland); Helen A. Mearns (Fallston, Maryland); Richard A. Newton (Reisterstown, Maryland); Joseph H. Keller (West Chester, Pennsylvania); Douglas B. Mawhinney (Ithaca, New York); John T. Yates, Jr. (Allison Park, Pennsylvania) |
| ABSTRACT | The invention provides reactive sorbents and methods of making and using the same in order to decontaminate surfaces contaminated with toxic agents, such as chemical warfare agents and/or industrial toxins. The reactive sorbents are of two general types, one of which comprises dehydroxylated aluminum oxide and the other comprises porous carbon impregnated with a reactive solution, so that both sorbents take up and then detoxify toxic agents. |
| FILED | Tuesday, June 04, 2002 |
| APPL NO | 10/162055 |
| ART UNIT | 1754 — Organic Chemistry |
| CURRENT CPC | Hazardous or toxic waste destruction or containment 588/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853067 | Cohn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Microassembly Technologies, Inc. (Richmond, California) |
| INVENTOR(S) | Michael B. Cohn (Berkeley, California); Joseph T. Kung (Santa Clara, California) |
| ABSTRACT | Improved microelectromechanical systems (MEMS), processes and apparatus using thermocompression bonding are disclosed. For example, process embodiments are disclosed in which wafer-scale as well as die-scale thermocompression bonding is utilized to encapsulate MEMS and/or to provide electrical interconnections with MEMS. Apparatus embodiments include apparatus for performing thermocompression bonding and bonded hybrid structures manufactured in accordance with the process embodiments. Devices having various substrate bonding and/or sealing configurations variously offer the advantage of reduced size, higher manufacturing yields, reduced costs, improved reliability, improved compatibility with existing semiconductor manufacturing process and/or greater versatility of applications. |
| FILED | Friday, February 28, 2003 |
| APPL NO | 10/377999 |
| ART UNIT | 2823 — Organic Chemistry |
| CURRENT CPC | Active solid-state devices 257/704 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853449 | Hocker |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | G. Benjamin Hocker (Minnetonka, Minnesota) |
| ABSTRACT | A programmable substance detector includes a light source, a sample cell, a programmable diffraction grating positioned to receive light from the light source and to direct diffracted light to the sample cell, and a detector associated with the cell to detect a match between a characteristic of the diffracted light and a corresponding characteristic of a substance within the cell. |
| FILED | Tuesday, January 28, 2003 |
| APPL NO | 10/352828 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853765 | Cochran |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kevin Cochran (Alexandria, Virginia) |
| ABSTRACT | A MEMS type optical switch includes a substrate, the substrate including at least one groove formed therein; first and second optical fibers disposed in the at least one groove, the at least one groove including a widened portion for movement of at least one of the first and second optical fibers; a thermal actuator disposed adjacent one of the first and second optical fibers, the thermal actuator comprising at least one v-beam, a pair of anchors connected to ends of the v-beam, and a yoke disposed in a central portion of the v-beam. |
| FILED | Monday, March 31, 2003 |
| APPL NO | 10/401951 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853875 | Moritz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Elan Moritz (Lynn Haven, Florida); Helmut Portmann (Panama City Beach, Florida) |
| ABSTRACT | An unmanned system is provided for the handling and delivery of a plurality of operational payloads. Each of a plurality of standardized shipping containers houses an operational payload, a controller that controls functions of the operational payload, and communication means that communicates with the controller. A structure is provided for supporting the shipping containers in a fixed relationship to one another so that the shipping containers can be handled and transported collectively by moving the structure. The structure is equipped with means to facilitate data transfer with each shipping container's controller. |
| FILED | Wednesday, March 20, 2002 |
| APPL NO | 10/101095 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/229 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853925 | Daniel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Isaac M. Daniel (Morton Grove, Illinois); Sun Kyoung Kim (Evanston, Illinois); Jeremy G. Opperer (Chicago, Illinois) |
| ABSTRACT | Methods to detect and characterize a defect in a fiber preform residing in a molding cavity for liquid composite molding (e.g. resin transfer molding) to make a composite component or structure. The defect may result from fiber preform misplacement in the molding cavity, accidental inclusions, preform density variations, and/or distortion of the preform. Gas pressures at multiple locations on a mold wall are measured during gas flow through the mold cavity containing the fiber preform. Normalized or measured pressures are analyzed by discriminant analysis to detect and characterize any defect in the tested fiber preform. |
| FILED | Tuesday, July 01, 2003 |
| APPL NO | 10/611318 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853926 | Alfano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Research Foundation of CUNY (New York, New York); Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Robert R. Alfano (Bronx, New York); Iosif Zeylikovich (Brooklyn, New York); Wubao Wang (Flushing, New York); Jamal Ali (Brooklyn, New York); Vincent Benischek (Shrub Oak, New York); Yury Budansky (Oakland, New Jersey) |
| ABSTRACT | The present invention provides systems and methods for non-destructively detecting material abnormalities beneath a coated surface, comprising a mid-infrared (MIR) detection unit for illuminating an area of the coated surface and detecting light reflected from the illuminated area of the coated surface, and a processing unit for producing an image from optical characteristics received from the MIR detection unit. In addition, the system may further comprise a scanning unit for moving the MIR detection unit to a next area. |
| FILED | Thursday, June 05, 2003 |
| APPL NO | 10/455662 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06854004 | Spence |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Scott E. Spence (Federicksburg, Virginia) |
| ABSTRACT | Using irregular optical interconnections to compensate for non-uniformities in analog optical processors, such as matrix-vector (M-V) optical processors, is disclosed. An M-V processor of one embodiments includes two optical devices, such as spatial light modulators (SLM's). One of the devices represents a matrix, and the other device represents a vector. Each device has non-uniformities. The non-uniformities of the devices are at least substantially matched to one another, where the optical interconnections between the devices are irregular. Light traveling through the devices represents the product of the matrix and the vector. An analog-to-digital (A/D) processor, or converter, can be used to subtract any errors in the product even after substantially matching the non-uniformities, by non-digital electrical or photonic processing. |
| FILED | Wednesday, December 26, 2001 |
| APPL NO | 10/028966 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/816 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06854058 | Carroll |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas L. Carroll (Alexandria, Virginia) |
| ABSTRACT | The low-interference communications device uses chaotic signals which are almost periodic. A chaotic circuit driven by a sine wave signal from a function generator is produced which has narrow-band features in the power spectrum. An information signal is encoded on the chaotic signal by modulating the phase of the sine wave that drives the chaotic circuit. Periodic (narrow-band) components are then removed from the chaotic signal and the chaotic signal is transmitted to a receiver device. The chaotic signal is nonlinear, so the narrow band and broad band parts of the chaotic signal have been modulated together. The transmitted signal is relatively flat, so it will not interfere with other communications signals. At the receiver, the nonlinear chaotic signal is restored by performing a nonlinear operation on the received signal, such as squaring or cubing, to remove the narrowband components. Then the information modulated onto the narrow band component is detected. When this is accomplished it is possible to detect variations in the phase of the base frequency. |
| FILED | Monday, April 23, 2001 |
| APPL NO | 09/839146 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/168 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06851175 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | David L Brown (Westfield, Indiana); Gerald R Stabel (Swartz Creek, Michigan); Robert Anthony Lawrence (Kokomo, Indiana) |
| ABSTRACT | A method of inserting coils in slots of a stator is provided. The method includes interleaving a first set of first phase windings and a first set of second phase windings on an insertion tool. The method also includes activating the insertion tool to radially insert the first set of first phase windings and the first set of second phase windings in the slots of the stator. In one embodiment, interleaving the first set of first phase windings and the first set of second phase windings on the insertion tool includes forming the first set of first phase windings in first phase openings defined in the insertion tool, and forming the first set of second phase windings in second phase openings defined in the insertion tool. |
| FILED | Wednesday, September 12, 2001 |
| APPL NO | 09/950853 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/596 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06851890 | Kostelnik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Bechtel BWXT Idaho, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Kevin M. Kostelnik (Idaho Falls, Idaho); Hideki Kawamura (Tokyo, Japan); John G. Richardson (Idaho Falls, Idaho); Masaru Noda (Tokyo, Japan) |
| ABSTRACT | An advanced containment system for containing buried waste and associated leachate. The advanced containment system comprises a plurality of casing sections with each casing section interlocked to an adjacent casing section. Each casing section includes a complementary interlocking structure that interlocks with the complementary interlocking structure on an adjacent casing section. A barrier filler substantially fills the casing sections and may substantially fill the spaces of the complementary interlocking structure to form a substantially impermeable barrier. Some of the casing sections may include sensors so that the casing sections and the zone of interest may be remotely monitored after the casing sections are emplaced in the ground. |
| FILED | Thursday, April 03, 2003 |
| APPL NO | 10/412491 |
| ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hydraulic and earth engineering 45/129.550 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852425 | Hu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ut-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Zhong-Cheng Hu (Knoxville, Tennessee) |
| ABSTRACT | The method of the invention is based on the unique electron-carrying function of a photocatalytic unit such as the photosynthesis system I (PSI) reaction center of the protein-chlorophyll complex isolated from chloroplasts. The method employs a photo-biomolecular metal deposition technique for precisely controlled nucleation and growth of metallic clusters/particles, e.g., platinum, palladium, and their alloys, etc., as well as for thin-film formation above the surface of a solid substrate. The photochemically mediated technique offers numerous advantages over traditional deposition methods including quantitative atom deposition control, high energy efficiency, and mild operating condition requirements. |
| FILED | Wednesday, February 19, 2003 |
| APPL NO | 10/369818 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/548 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852488 | Fodor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Affymetrix, Inc. (Santa Clara, California) |
| INVENTOR(S) | Stephen P. A. Fodor (Palo Alto, California); Robert J. Lipshutz (Palo Alto, California); Xiaohua Huang (Mt. View, California) |
| ABSTRACT | Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques. |
| FILED | Tuesday, February 06, 2001 |
| APPL NO | 09/776768 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852614 | Compaan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maine (Toledo, Ohio) |
| INVENTOR(S) | Alvin D. Compaan (Sylvania, Ohio); Kent J. Price (Toledo, Ohio); Xianda Ma (Milpitas, California); Konstantin Makhratchev (Fremont, California) |
| ABSTRACT | A method of making a semiconductor comprises depositing a group II-group VI compound onto a substrate in the presence of nitrogen using sputtering to produce a nitrogen-doped semiconductor. This method can be used for making a photovoltaic cell using sputtering to apply a back contact layer of group II-group VI compound to a substrate in the presence of nitrogen, the back coating layer being doped with nitrogen. A semiconductor comprising a group II-group VI compound doped with nitrogen, and a photovoltaic cell comprising a substrate on which is deposited a layer of a group II-group VI compound doped with nitrogen, are also included. |
| FILED | Friday, March 23, 2001 |
| APPL NO | 09/815958 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/603 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853196 | Barnum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | John R. Barnum (Albuquerque, New Mexico); Larry K. Warne (Albuquerque, New Mexico); Roy E. Jorgenson (Albuquerque, New Mexico); Larry X. Schneider (Albuquerque, New Mexico) |
| ABSTRACT | A method for electrical cable testing by Pulse-Arrested Spark Discharge (PASD) uses the cable response to a short-duration high-voltage incident pulse to determine the location of an electrical breakdown that occurs at a defect site in the cable. The apparatus for cable testing by PASD includes a pulser for generating the short-duration high-voltage incident pulse, at least one diagnostic sensor to detect the incident pulse and the breakdown-induced reflected and/or transmitted pulses propagating from the electrical breakdown at the defect site, and a transient recorder to record the cable response. The method and apparatus are particularly useful to determine the location of defect sites in critical but inaccessible electrical cabling systems in aging aircraft, ships, nuclear power plants, and industrial complexes. |
| FILED | Friday, April 12, 2002 |
| APPL NO | 10/122448 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/543 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853472 | Warner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
| INVENTOR(S) | Benjamin P. Warner (Los Alamos, New Mexico); T. Mark McCleskey (Los Alamos, New Mexico); Anoop Agrawal (Tucson, Arizona); John P. Cronin (Tucson, Arizona); Juan C. L. Tonazzi (Tucson, Arizona); Anthony K. Burrell (Los Alamos, New Mexico) |
| ABSTRACT | Electrolyte solutions of soluble bifunctional redox dyes in molten salt solvent may be used to prepare electrooptic devices with enhanced stability toward ultraviolet radiation. The solvents include lithium or quaternary ammonium cations, and perfluorinated sulfonylimide anions selected from trifluoromethylsulfonate (CF3SO3−), bis(trifluoromethylsulfonyl)imide ((CF3SO2)2N−), bis(perfluoroethylsulfonyl)imide ((CF3CF2SO2)2N−) and tris(trifluoromethylsulfonyl)methide ((CF3SO2)3C−). |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600807 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853669 | Simpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | John T. Simpson (Knoxville, Tennessee); Marcus L. Simpson (Knoxville, Tennessee); Stephen P. Withrow (Oak Ridge, Tennessee); Clark W. White (Oak Ridge, Tennessee); Supriya L. Jaiswal (Knoxville, Tennessee) |
| ABSTRACT | A solid state laser includes an optical waveguide and a laser cavity including at least one subwavelength mirror disposed in or on the optical waveguide. A plurality of photoluminescent nanocrystals are disposed in the laser cavity. The reflective subwavelength mirror can be a pair of subwavelength resonant gratings (SWG), a pair of photonic crystal structures (PC), or a distributed feedback structure. In the case of a pair of mirrors, a PC which is substantially transmissive at an operating wavelength of the laser can be disposed in the laser cavity between the subwavelength mirrors to improve the mode structure, coherence and overall efficiency of the laser. A method for forming a solid state laser includes the steps of providing an optical waveguide, creating a laser cavity in the optical waveguide by disposing at least one subwavelength mirror on or in the waveguide, and positioning a plurality of photoluminescent nanocrystals in the laser cavity. |
| FILED | Tuesday, December 10, 2002 |
| APPL NO | 10/315578 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/92 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853798 | Weiss |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Jonathan D. Weiss (Albuquerque, New Mexico) |
| ABSTRACT | A new class of optical fiber based thermal sensors has been invented. The new sensors comprise hydrogen-resistant optical fibers which are able to withstand a hot, hydrogen-containing environment as is often found in the downhole well environment. |
| FILED | Friday, March 22, 2002 |
| APPL NO | 10/104216 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Optical waveguides 385/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853951 | Jarrell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Donald B. Jarrell (Kennewick, Washington); Daniel R. Sisk (Richland, Washington); Darrel D. Hatley (Kennewick, Washington); Leslie J. Kirihara (Richland, Washington); Timothy J. Peters (Richland, Washington) |
| ABSTRACT | Methods and systems for identifying, understanding, and predicting the degradation and failure of mechanical systems are disclosed. The methods include measuring and quantifying stressors that are responsible for the activation of degradation mechanisms in the machine component of interest. The intensity of the stressor may be correlated with the rate of physical degradation according to some determinable function such that a derivative relationship exists between the machine performance, degradation, and the underlying stressor. The derivative relationship may be used to make diagnostic and prognostic calculations concerning the performance and projected life of the machine. These calculations may be performed in real time to allow the machine operator to quickly adjust the operational parameters of the machinery in order to help minimize or eliminate the effects of the degradation mechanism, thereby prolonging the life of the machine. Various systems implementing the methods are also disclosed. |
| FILED | Monday, December 09, 2002 |
| APPL NO | 10/316199 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06851587 | Tseng |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents (Tempe, Arizona) |
| INVENTOR(S) | Ampere A. Tseng (Phoenix, Arizona) |
| ABSTRACT | An apparatus for forming three-dimensional objects includes a crucible (1) for holding a molten material; a conically-shaped orifice (1a) having a fixed outlet diameter (d0) at the bottom of the crucible through which a jet (50) of the molten material flows towards the substrate; and an oscillating mechanical member (5) for breaking the flow of molten material into the molten material drops (60). The oscillating mechanical member further includes a conically-shaped head (5a) for cooperating with the orifice (1a) and for varying the effective size of the orifice. The conically-shaped head includes a slanted radial portion (5c) and a tip portion (5b) extending through the orifice. The effective diameter (deff) of the jet is defined by the relationship deff=[d02−(d0−δ tan θ)2]1/2, wherein δ represents the amount of the tip portion extending through the orifice, and θ represents a slant angle corresponding to the slanted radial portion of the conically-shaped head. |
| FILED | Tuesday, November 16, 1999 |
| APPL NO | 09/868471 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Dispensing 222/590 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852195 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Kevin P. Martin (Atlanta, Georgia); Harry P. Gillis (Los Angeles, California); Dmitri A. Choutov (Santa Clara, California) |
| ABSTRACT | An apparatus for low-damage, anisotropic etching of substrates having the substrate mounted upon a mechanical support located within an ac or dc plasma reactor. The mechanical support is independent of the plasma reactor generating apparatus and capable of being electrically biased. The substrate is subjected to plasma of low-energy electrons and a species reactive with the substrate. An additional structure capable of being electrically biased can be placed within the plasma to control further the extraction or retardation of particles from the plasma. |
| FILED | Tuesday, May 15, 2001 |
| APPL NO | 09/855972 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/345.470 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852252 | Halas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Nancy J. Halas (Houston, Texas); Gregory David Hale (Houston, Texas) |
| ABSTRACT | The present invention relates to incorporating metal nanoshells specifically designed to interact with triplet excitons in polymers. By interacting with triplet excitons, the rate of photo-oxidation can be slowed and the density of luminescence-quenching traps can be reduced. |
| FILED | Friday, April 06, 2001 |
| APPL NO | 09/827588 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/582 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852285 | Abbott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Justin J. Skaife (Lafayette, California); Vinay K. Gupta (Urbana, Illinois); Timothy B. Dubrovsky (Flemington, New Jersey); Rahul Shah (Davis, California) |
| ABSTRACT | Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction. |
| FILED | Tuesday, July 03, 2001 |
| APPL NO | 09/898132 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852544 | Aebersold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Rudolf Hans Aebersold (Mercer Island, Washington); Michael H. Gelb (Seattle, Washington); Steven P. Gygi (Seattle, Washington); C. Ronald Scott (Seattle, Washington); Frantisek Turecek (Seattle, Washington); Scott A. Gerber (Seattle, Washington); Beate Rist (Seattle, Washington) |
| ABSTRACT | Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques. The reagents also provide for differential isotopic labeling of the isolated peptides or reaction products which facilitates quantitative determination by mass spectrometry of the relative amounts of proteins in different samples. The methods of this invention can be used for qualitative and quantitative analysis of global protein expression profiles in cells and tissues, to screen for and identify proteins whose expression level in cells, tissue or biological fluids is affected by a stimulus or by a change in condition or state of the cell, tissue or organism from which the sample originated. |
| FILED | Friday, April 20, 2001 |
| APPL NO | 09/839884 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852804 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Joseph P. Kennedy (Akron, Ohio); Ralf M. Peetz (Akron, Ohio); Ahmed F. Moustafa (Cairo, Egypt) |
| ABSTRACT | Block copolymers having a polyisobutylene segment and a polycycloaliphatic diene polymer segment are presented. Star block copolymers with 2 to 16 block copolymer arms, wherein each of the arms has a polyisobutylene segment and a polycycloaliphatic diene polymer segment, are presented. The star block copolymers are synthesized via the “core first” method. |
| FILED | Friday, April 25, 2003 |
| APPL NO | 10/424035 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/297 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852835 | Collmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan Collmer (Ithaca, New York); James R. Alfano (Lincoln, Nebraska); Amy O. Charkowski (Oakland, California) |
| ABSTRACT | One aspect of the present invention relates to isolated nucleic acid molecules (i) encoding proteins or polypeptides of Pseudomonas CEL and EEL genomic regions, (ii) nucleic acid molecules which hybridize thereto under stringent conditions, or (iii) nucleic acid molecules that include a nucleotide sequence which is complementary to the nucleic acid molecules of (i) and (ii). Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The nucleic acid molecules and proteins of the present invention can be used to imparting disease resistance to a plant, making a plant hypersusceptible to colonization by nonpathogenic bacteria, causing eukaryotic cell death, and treating cancerous conditions. |
| FILED | Tuesday, April 03, 2001 |
| APPL NO | 09/825414 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853331 | Belen'kii et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); University Corporation for Atmospheric Research (Boulder, Colorado) |
| INVENTOR(S) | Mikhail S. Belen'kii (San Diego, California); Ernest Jefferson Holder (Marietta, Georgia); Susan Ferebee Dugas (Woodstock, Georgia); Christian Rocken (Boulder, Colorado); Anthony Lowry (Boulder, Colorado) |
| ABSTRACT | A method of compensating for atmospheric effects to detect the actual location of low elevation objects using near horizon radar to detect an object which utilizes a preexisting satellite structured to send a signal indicating the position and velocity of said satellite, wherein the location of the satellite is known. The method includes a step of providing a radar site, a first receiver structured to receive a signal from the satellite indicating an apparent location of the satellite, and a second receiver, located at a distance from the radar site, structured to receive the satellite signal and which indicates the observed location of the satellite. The first receiver is utilized to receive a signal from the satellite when the satellite is at a low elevation. This signal indicates the apparent location and velocity of the satellite. The bending angle can then be determined by comparing the apparent location data of the satellite as determined by the first receiver to the observed location data of the satellite. The satellite signal is used to determine the Doppler shift of the signal at the radar site as compared to the signal from the observed location. The Doppler shift data is used to determine the bending angle. Once the bending angle of the atmosphere is determined, the radar is used to detect the apparent location data of a low elevation object. The location of the low elevation object can then be determined by applying the bending angle to the apparent location data of the object. |
| FILED | Thursday, February 20, 2003 |
| APPL NO | 10/370256 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853926 | Alfano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Research Foundation of CUNY (New York, New York); Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Robert R. Alfano (Bronx, New York); Iosif Zeylikovich (Brooklyn, New York); Wubao Wang (Flushing, New York); Jamal Ali (Brooklyn, New York); Vincent Benischek (Shrub Oak, New York); Yury Budansky (Oakland, New Jersey) |
| ABSTRACT | The present invention provides systems and methods for non-destructively detecting material abnormalities beneath a coated surface, comprising a mid-infrared (MIR) detection unit for illuminating an area of the coated surface and detecting light reflected from the illuminated area of the coated surface, and a processing unit for producing an image from optical characteristics received from the MIR detection unit. In addition, the system may further comprise a scanning unit for moving the MIR detection unit to a next area. |
| FILED | Thursday, June 05, 2003 |
| APPL NO | 10/455662 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 06851463 | Socci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | AlliedSignal Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Edward Peter Socci (Stewartsville, New Jersey); Young Doo Kwon (Mendham, New Jersey); Charles Jay Nelson (Richmond, Virginia); Thomas Hoyt Golden (Denville, New Jersey); Jeffrey Donald Pratt (Budd Lake, New Jersey); Uday Bharatkumar Jhaveri (Westfield, New Jersey) |
| ABSTRACT | The present invention provides an improved fiber-reinforced article comprised of at least two plies. Each of the plies comprises (a) rubber and (b) cord made from melt-spinnable, non-metallic, multifilament fibers for which the cord has a twist multiplier of less than or equal to about 375, a stress at 1% strain greater than or equal to about 1.7 grams/denier, and an initial compressive modulus greater than or equal to about 7 grams/denier, and the at least two plies have a fiber orientation angle of greater than or equal to about 23°. The composite is useful as a tire belt in a passenger tire. |
| FILED | Thursday, April 08, 1999 |
| APPL NO | 09/288589 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Resilient tires and wheels 152/527 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852139 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Excellatron Solid State, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Ji-Guang Zhang (Marietta, Georgia); Lamartine Meda (Atlanta, Georgia); Eleston Maxie (Marietta, Georgia) |
| ABSTRACT | A process of producing a thin film electrolyte is provided wherein a volatile lithium-containing precursor and a volatile phosphate-containing precursor are mixed into a plasma generated from a plasma source. The mixture is then deposited upon a substrate. The process is conducted with the use of a system (11) having a plasma source (13) having a primary plenum (16) and a secondary plenum (23). The primary plenum is in fluid communication with a source of nitrogen gas (47) and a source of hydrogen gas (51). The secondary plenum is in fluid communication with a first bubbler (31) and a second bubbler (38). |
| FILED | Friday, July 11, 2003 |
| APPL NO | 10/617839 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Metal working 029/623.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853131 | Srivastava et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Alok Mani Srivastava (Niskayuna, New York); Anil Raj Duggal (Niskayuna, New York); Holly Ann Comanzo (Niskayuna, New York); William Winder Beers (Chesterland, Ohio) |
| ABSTRACT | There is provided a white light illumination system. The illumination system includes a radiation source which emits either ultra-violet (UV) or x-ray radiation. The illumination system also includes a luminescent material which absorbs the UV or x-ray radiation and emits the white light. The luminescent material has composition A2−2xNa1+xExD2V3O12. A may be calcium, barium, strontium, or combinations of these three elements. E may be europium, dysprosium, samarium, thulium, or erbium, or combinations thereof. D may be magnesium or zinc, or combinations thereof. The value of x ranges from 0.01 to 0.3, inclusive. |
| FILED | Tuesday, November 12, 2002 |
| APPL NO | 10/291414 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/503 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06853479 | Ilchenko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | OEwaves, Inc. (Pasadena, California) |
| INVENTOR(S) | Vladimir S. Ilchenko (La Canada, California); Dmitri Kossakovski (South Pasadena, California); Kouros Sariri (Encino, California) |
| ABSTRACT | A system includes an electro-absorptive modulator having opposing surfaces, a first semiconductor optical amplifier having opposing surfaces, a photodetector having opposing surfaces, a second semiconductor optical amplifier having opposing surfaces, a microwave link, and an optical resonator. One of the opposing surfaces of the first semiconductor optical amplifier is coupled to one of the opposing surfaces of the electro-absorptive modulator. One of the opposing surfaces of the second semiconductor optical amplifier is coupled to one of the opposing surfaces of the photodetector. The microwave link is coupled between the photodetector and the electro-absorptive modulator. The optical resonator is for coupling evanescent components of light propagated between the first semiconductor optical amplifier and the second semiconductor optical amplifier. |
| FILED | Friday, August 30, 2002 |
| APPL NO | 10/231860 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optical: Systems and elements 359/337.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 06852315 | Piazza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | George J. Piazza (Meadowbrook, Pennsylvania); Thomas A. Foglia (Lafayette Hill, Pennsylvania); Alberto Nunez (Dresher, Pennsylvania) |
| ABSTRACT | A method has been discovered for the epoxidation of a compound having at least one carbon-carbon double bond, the method involves reacting a compound having at least one carbon-carbon double bond, a solvent, an oxidant, and membrane bound peroxygenase. Also discovered is a method for preparing the membrane bound peroxygenase involving grinding seeds containing peroxygenase to produce ground seeds, homogenizing the ground seeds in a buffer to form a slurry, centrifuging the slurry to produce a first supernatant, centrifuging the first supernatant to produce a second supernatant, and filtering said second supernatant through a protein-binding membrane filter to produce membrane bound peroxygenase; optionally the second supernatant is filtered through a hydrophilic membrane filter prior to filtering the second supernatant through a protein-binding membrane filter. |
| FILED | Thursday, October 03, 2002 |
| APPL NO | 10/262937 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852835 | Collmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan Collmer (Ithaca, New York); James R. Alfano (Lincoln, Nebraska); Amy O. Charkowski (Oakland, California) |
| ABSTRACT | One aspect of the present invention relates to isolated nucleic acid molecules (i) encoding proteins or polypeptides of Pseudomonas CEL and EEL genomic regions, (ii) nucleic acid molecules which hybridize thereto under stringent conditions, or (iii) nucleic acid molecules that include a nucleotide sequence which is complementary to the nucleic acid molecules of (i) and (ii). Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The nucleic acid molecules and proteins of the present invention can be used to imparting disease resistance to a plant, making a plant hypersusceptible to colonization by nonpathogenic bacteria, causing eukaryotic cell death, and treating cancerous conditions. |
| FILED | Tuesday, April 03, 2001 |
| APPL NO | 09/825414 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06851647 | Rosenbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Bernard J. Rosenbaum (Seabrook, Texas); George E. Petter (Houston, Texas); Joseph A. Gessler (Houston, Texas); Michael G. Hughes (Pasadena, Texas) |
| ABSTRACT | An apparatus for launching an aircraft having a multiplicity of interconnected elongated tracks of rigid material forming a track system and wherein each elongated track has a predetermined elongated track cross-sectional design, a winch system connected to the track system wherein the winch system has a variable mechanical advantage, one or more elongated elastic members wherein one end of each of the one or more elongated elastic members is adjustably connected to the track system, and a carrier slidably mounted to the track system wherein the carrier is connected to the winch system and to the other end of each of the one or more elongated elastic members. |
| FILED | Thursday, April 03, 2003 |
| APPL NO | 10/417377 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852170 | Williams |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Glenn L. Williams (Bay Village, Ohio) |
| ABSTRACT | The method of using the mouse pad cleaning apparatus is disclosed and claimed. The method comprises the steps of uncovering the mouse cleaning surface, applying the mouse and ball of the mouse to the cleaning surface, moving the mouse in a rotational pattern on the mouse cleaning surface, removing the mouse form the mouse cleaning surface, washing the cleaning surface, and covering the mouse cleaning surface. A mouse pad cleaning apparatus comprising a plurality of substrates, each said substrate having adhesive thereon, said plurality of substrates residing in and affixed to a receptacle. A single substrate having adhesive, which may be washable or non-washable, thereon may be employed. The washable adhesive may be an organopolysiloxane or gelatinous elastomer. |
| FILED | Thursday, October 03, 2002 |
| APPL NO | 10/264189 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Cleaning and liquid contact with solids 134/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 06853919 | Kellum |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Motors Corporation (Detroit, Michigan) |
| INVENTOR(S) | Carroll C. Kellum (Rochester Hills, Michigan) |
| ABSTRACT | A method for reducing repetitive false alarm indications in a vehicle impact detection system for a host vehicle includes generating false alarm positional information corresponding to a detected object determined to be a false alarm. The false alarm is determined subsequent to an issued warning to a driver, and the false alarm positional information is stored in a database. The false alarm positional information in the database is further evaluated to determine, based on predefined removal criteria, whether any of the false alarm positional information in the database is to be removed therefrom. The false alarm positional information remaining in the database is used to inhibit the issuance of a warning to a driver of the host vehicle. |
| FILED | Tuesday, February 04, 2003 |
| APPL NO | 10/358131 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 06852517 | Suthers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Patrick F. Suthers (Madison, Wisconsin); Douglas C. Cameron (N. Plymouth, Minnesota) |
| ABSTRACT | The production of 3-hydroxypropionic acid (3-HP) from glycerol in a bacterial host is described. 3-HP is a useful feedstock for the production of polymeric materials. The genetic engineering of a bacterial host with two enzymes is sufficient to enable production of 3-HP. One enzyme is a glycerol dehydratase and the other is an aldehyde dehydrogenase. |
| FILED | Wednesday, August 30, 2000 |
| APPL NO | 09/830751 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/135 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
06852531 — Compositions and methods for reproducing and modulating mammalian messenger RNA decapping
| US 06852531 | Wilusz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Medicine and Dentistry of NJ (New Brunswick, New Jersey) |
| INVENTOR(S) | Jeffrey Wilusz (Lebanon, New Jersey); Carol Wilusz (Lebanon, New Jersey); Min Gao (San Diego, California) |
| ABSTRACT | An in-vitro system in which mammalian messenger RNA decapping occurs is provided, for use in identifying modulators, deficiencies, and other aspects of the regulation of RNA turnover. |
| FILED | Tuesday, September 18, 2001 |
| APPL NO | 09/955462 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06852907 | Padidam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Malla Padidam (Lansdale, Pennsylvania); Roger N. Beachy (St. Louis, Missouri); Claude M. Fauquet (Del Mar, California) |
| ABSTRACT | The invention describes methods for producing plant resistance to a ssDNA virus, particularly a geminivirus such as mastrevirus, curtovirus or begomovirus. The method comprises introducing a ssDNA-binding protein of the Inoviridae virus into the plant, and includes a phage coat protein, particularly, a coliphage gene 5 protein. The invention also describes a transgenic plant comprising a gene that expresses the ssDNA-binding protein and vectors for expressing the protein in plants. |
| FILED | Wednesday, March 03, 1999 |
| APPL NO | 09/622500 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 08, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050208.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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