FedInvent™ Patents

Patent Details for Tuesday, March 15, 2005 

This page was updated on Sunday, March 26, 2023 at 07:45 PM GMT

Department of Health and Human Services (HHS) 

US 06866843 Habener et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Viacell, Inc. (Charlestown, Massachusetts)
INVENTOR(S) Joel F. Habener (Newton Centre, Massachusetts);  Henryk Zulewski (Basel, Switzerland);  Elizabeth Abraham (Quincy, Massachusetts);  Mario Vallejo (Madrid, Spain);  Denise L. Faustman (Weston, Massachusetts);  Melissa K. Thomas (Boston, Massachusetts)
ABSTRACT Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation into a variety of pancreatic islet cells, including insulin-producing beta cells, as well as hepatocytes. Nestin has been identified as a molecular marker for pancreatic stem cells, while cytokeratin-19 serves as a marker for a distinct class of islet ductal cells. Methods are described whereby nestin-positive stem cells can be isolated from pancreatic islets and cultured to obtain further stem cells or pseudo-islet like structures. Methods for ex vivo differentiation of the pancreatic stem cells are disclosed. Methods are described whereby pancreatic stem cells can be isolated, expanded, and transplanted into a patient in need thereof, either allogeneically, isogeneically or xenogenically, to provide replacement for lost or damaged insulin-secreting cells or other cells.
FILED Wednesday, December 06, 2000
APPL NO 09/731255
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06866845 Ward et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Peter A. Ward (Ann Arbor, Michigan);  Markus Huber-Lang (South Lyon, Michigan);  Vidya Sarma (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for the prevention and treatment of blood-borne and toxin mediated diseases, and in particular anti-C5a antibodies for the prevention and treatment of sepsis in humans as well as other animals. The present invention also relates to methods of generating anti-C5a antibodies employing C-terminal truncated C5a peptides.
FILED Wednesday, August 30, 2000
APPL NO 09/651685
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/139.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06866851 Milbrandt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Jeffrey D. Milbrandt (St. Louis, Missouri);  Robert H. Baloh (St. Louis, Missouri)
ABSTRACT Chimeric GDNF family ligands which activate a GFRα/RET are disclosed. Included are chimeras which activate GFRα1/RET but do not activate GFRα2-RET or GFRα3-RET. The chimeras are useful in providing trophic support to a mammalian cell or in producing differentiation of a mammalian cell, or both, particularly when the cell is in a patient suffering from various diseases, in particular Parkinson's Disease.
FILED Tuesday, December 28, 1999
APPL NO 09/473551
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/192.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06866854 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Yuan Chang (Irvington, New York);  Patrick S. Moore (Irvington, New York)
ABSTRACT This invention provides an isolated nucleic acid which encodes a Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 2 polypeptide (LANA2) or a fragment thereof and also provides the LANA2 polypeptide. This invention provides an isolated nucleic acid comprising consecutive nucleotides having the sequence of a promoter of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 2 transcription. This invention also provides a method of inhibiting p53 mediated apoptosis of a cell and a method of producing an antibody which comprises introducing into a cell a replicable vector of the subject invention.
FILED Friday, September 05, 2003
APPL NO 10/656499
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/229.100
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US 06867008 Mendelsohn
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) New England Medical Center Hospitals, Inc. (Boston, Massachusetts)
INVENTOR(S) Michael E. Mendelsohn (Wellesley, Massachusetts)
ABSTRACT The invention provides a method for assaying compounds that affect cell division by determining the interaction between estrogen receptor ERβ and MAD2, a cell cycle checkpoint protein.
FILED Tuesday, July 13, 1999
APPL NO 09/352570
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
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US 06867017 Dean et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Michael Dean (Frederick, Maryland);  Rando Allikmets (Monroe, New York);  Amy Ann Hutchinson (Fort Lee, New Jersey)
ABSTRACT Disclosed is a novel ATP-binding cassette gene (ABC7), polypeptide and methods of detecting mutations therein. Further, the disclosure provides methods of detecting ABC7 associated disease and treatments thereof. In particular, the disclosure provides methods of detecting X-linked Sideroblastic Anemia and Ataxia associated with a mutation in the ABC7 polypeptide.
FILED Thursday, October 21, 1999
APPL NO 09/422840
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867020 Powell
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Washington (Seattle, Washington)
INVENTOR(S) Jerry S. Powell (Seattle, Washington)
ABSTRACT The Apa I restriction fragment of the human erythropoietin gene, for producing high titers of biologically active hormone from stably transfected cell lines.
FILED Wednesday, October 10, 2001
APPL NO 09/975063
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867022 Imperiale
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Michael J. Imperiale (Ann Arbor, Michigan)
ABSTRACT The invention provides novel replication deficient adenovirus vectors and methods for making and using these viruses. The invention also provides vector systems and kits using a serotype specific strategy for making adenoviral vector preparations substantially free of replication competent “helper” virus. The helper virus-free preparations provide novel pharmaceutical compositions substantially free of helper virus for use in gene transfer and gene therapy.
FILED Friday, January 21, 2000
APPL NO 09/488867
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867034 Alexander et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Curators of The University of Missouri (Columbia, Missouri)
INVENTOR(S) Hannah Alexander (Columbia, Missouri);  Stephen Alexander (Columbia, Missouri)
ABSTRACT The present invention provides for methods of screening agents for cancer therapeutic and prophylactic activity. In particular embodiments, cells of the cellular slime mold Dictyostelium discoideum are contacted with candidate agents and the expression of genes in the Nucleotide Excision Repair (NER) and Base Excision Repair (BER) pathways are examined. Such genes include the helicases repB and repD, and the apurinic-apyrmidinic endonuclease APE.
FILED Tuesday, June 08, 2004
APPL NO 10/863670
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867038 Liotta et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Lance A. Liotta (Potomac, Maryland);  Michael Emmert-Buck (Silver Spring, Maryland);  David B. Krizman (Gaithersburg, Maryland);  Rodrigo Chuaqui (Las Condes, Chile);  W. Marston Linehan (North Bethesda, Maryland);  Jeffry M. Trent (Rockville, Maryland);  Robert F. Bonner (Washington, District of Columbia);  Seth R. Goldstein (Bethesda, Maryland);  Paul D. Smith (Annapolis, Maryland);  John I. Peterson (Falls Church, Virginia)
ABSTRACT A method of microdissection which involves forming an image field of cells of the tissue sample utilizing a microscope, identifying at least one zone of cells of interest from the image field of cells which at least one zone of cells of interest includes different types of cells than adjacent zones of cells, and extracting the at least one zone of cells of interest from the tissue sample. The extraction is achieved by contacting the tissue sample with a transfer surface that can be selectively activated so that regions thereof adhere to the zone of cells of interest to be extracted. The transfer surface includes a selectively activatable adhesive layer which provides, for example, chemical or electrostatic adherence to the selected regions of the tissue sample. After the transfer surface is activated, the transfer surface and tissue sample are separated. During separation, the zone of cells of interest remains adhered to the transfer surface and is thus separated from the tissue sample, the zone of cells of interest may then be molecularly analyzed.
FILED Friday, February 09, 2001
APPL NO 09/780234
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 06867177 Pinsky
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) David J. Pinsky (Cresskill, New Jersey)
ABSTRACT The present invention provides a method of treating or preventing thrombotic or ischemic disorders in a subject which comprises administering an agent to the subject, wherein the agent inhibits ADP-mediated platelet aggregation by increasing ADP catabolism, and a method for determining whether a compound inhibits platelet aggregation by increasing ADP catabolism so as to treat or prevent thrombotic or ischemic disorders in a subject, comprising: (a) inducing thrombotic or ischemic disorders in an animal, which animal is an animal model for thrombotic or ischemic disorders; (b) measuring the stroke outcome in the animal, (c) measuring platelet deposition and/or fibrin deposition in ischemic tissue, and (d) comparing the stroke outcome in step (b) and the platelet deposition and/or fibrin deposition with that of the animal model in the absence of the compound so as to identify a compound capable of treating or preventing thrombotic or ischemic disorders in a subject.
FILED Friday, August 13, 1999
APPL NO 09/374586
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 06867180 Tosato et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Giovanna Tosato (Bethesda, Maryland);  Sandra E. Pike (North Bethesda, Maryland);  Lei Yao (Rockville, Maryland)
ABSTRACT Methods for inhibiting endothelial cell growth and angiogenesis, and suppressing tumor growth using calreticulin, fragments of calreticulin and variants of calreticulin are provided. Such methods are useful for the treatment of cancer and diseases associated with unwanted angiogenesis, for example chronic retinal detachment.
FILED Tuesday, October 05, 1999
APPL NO 09/807148
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867187 Clevenger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Charles V. Clevenger (Merion Station, Pennsylvania);  J. Bradford Kline (Blue Bell, Pennsylvania)
ABSTRACT A human prolactin-binding protein and compositions and methods using this protein are provided.
FILED Friday, December 21, 2001
APPL NO 10/029079
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867190 Carney
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Darrell H. Carney (Dickinson, Texas)
ABSTRACT The present invention relates to a method for promoting cardiac tissue repair comprising administering to the cardiac tissue a therapeutically effective amount of an angiogenic thrombin derivative peptide and/or inhibiting or reducing vascular occlusion or restenosis. The invention also relates to methods of stimulating revascularization. In yet another embodiment, the invention relates to the use of thrombin derivative peptides in the manufacture of a medicament for the methods described herein.
FILED Thursday, July 12, 2001
APPL NO 09/904090
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/13
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US 06867194 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Peng George Wang (Troy, Michigan);  Xuejun Wu (Detroit, Michigan);  Xiaoping Tang (Lansdale, Pennsylvania)
ABSTRACT Sugar-modified SIN-1 compositions are provided. The compositions are useful for generating NO in response to hydrolytic activity of a glycosidase specific for the O-glycosidic bond between the sugar and SIN-1 moieties. Pharmaceutical compositions containing the sugar-modified SIN-1 compositions and methods of using the compositions are also provided.
FILED Thursday, August 09, 2001
APPL NO 09/925816
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/26
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867196 Wolff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Mirus Bio Corporation (Madison, Wisconsin)
INVENTOR(S) Jon A. Wolff (Madison, Wisconsin);  Hans Herweijer (Madison, Wisconsin);  Larry F. Whitesell (Lodi, Wisconsin);  Matthew R. Wolff (Middleton, Wisconsin);  Sean D. Monahan (Madison, Wisconsin);  Paul M. Slattum (Madison, Wisconsin);  James E. Hagstrom (Middleton, Wisconsin);  Vladimir G. Budker (Middleton, Wisconsin);  David B. Rozema (Madison, Wisconsin)
ABSTRACT A process for delivering a nucleic acid to a cardiac tissue cell in a mammal is described, comprising introducing a composition consisting of a nucleic acid to a blood vessel, which subsequently delivers the nucleic acid to the cardiac tissue cell. The nucleic acid can be DNA or RNA or plasmid DNA or viral. This process is for purposes of gene therapy, and research.
FILED Friday, June 11, 1999
APPL NO 09/330909
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867219 Horwitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Jerome P. Horwitz (Farmington Hills, Michigan);  Stuart T. Hazeldine (Taylor, Michigan);  Thomas H. Corbett (Grosse Pointe Park, Michigan);  Lisa Polin (Oak Park, Michigan)
ABSTRACT The invention provides compounds of formula I:
wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.
FILED Wednesday, July 31, 2002
APPL NO 10/210781
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/312
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US 06867227 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) W. David Wilson (Atlanta, Georgia);  David W. Boykin (Atlanta, Georgia);  Richard R. Tidwell (Pittsboro, North Carolina)
ABSTRACT Asymmetric derivatives of furamidines with one of the phenyl rings of furamidine replaced with a benzimidazole have been found by quantitative footprinting analyses to bind GC containing sites on DNA more strongly than to pure AT sequences. These compounds have been shown to bind in the minor groove at specific GC containing sequences of DNA in a highly cooperative manner as a stacked dimer. Compounds of the present invention find use in selectively binding mixed sequence DNA, and may also be used in methods of regulating gene expression, methods of treating opportunistic infections and cancer, as well as in methods of detecting certain sequences of DNA.
FILED Tuesday, September 02, 2003
APPL NO 10/653677
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/375
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US 06867289 Gorenstein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas Systems (Austin, Texas)
INVENTOR(S) David G. Gorenstein (Houston, Texas);  Bruce A. Luxon (Galveston, Texas);  Norbert Herzog (Friendswood, Texas);  Judy Aronson (Galveston, Texas)
ABSTRACT This invention generally relates the generation of aptamers and to the use of aptamers as diagnostic and therapeutic agents. More particularly, the present invention relates to methods using combinatorial chemistry to prepare aptamers having controlled thiophosphate replacement in the phosphate backbone for improved binding efficiencies to a target and to RNA and/or DNA products having novel nucleotide sequences and enhanced target binding efficacies.
FILED Monday, October 25, 1999
APPL NO 09/425804
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867292 Band et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Hamid Band (Brookline, Massachusetts);  Francescopaolo Borriello (Boston, Massachusetts)
ABSTRACT The invention pertains to nucleic acids encoding a cbl-SL protein, including fragments and biologically functional variants thereof. The invention also pertains to therapeutics and diagnostics involving the foregoing proteins and genes and agents that bind the foregoing proteins and genes.
FILED Friday, November 05, 1999
APPL NO 09/434708
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.500
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US 06867298 Buchwald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge MA, None)
INVENTOR(S) Stephen L. Buchwald (Newton, Massachusetts);  Artis Klapars (Cambridge, Massachusetts);  Jon C. Antilla (Malden, Massachusetts);  Gabriel E. Job (Quincy, Massachusetts);  Martina Wolter (Berlin, Germany);  Fuk Y. Kwong (Cambridge, Massachusetts);  Gero Nordmann (Boston, Massachusetts);  Edward J. Hennessy (Boston, Massachusetts)
ABSTRACT The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or amine moiety and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In additional embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between a nitrogen atom of an acyl hydrazine and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In other embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of a nitrogen-containing heteroaromatic, e.g., indole, pyrazole, and indazole, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-oxygen bond between the oxygen atom of an alcohol and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. The present invention also relates to copper-catalyzed methods of forming a carbon-carbon bond between a reactant comprising a nucleophilic carbon atom, e.g., an enolate or malonate anion, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. Importantly, all the methods of the present invention are relatively inexpensive to practice due to the low cost of the copper comprised by the catalysts.
FILED Thursday, May 08, 2003
APPL NO 10/435719
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
540/489
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US 06867302 Smith, III et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Milton R. Smith, III (East Lansing, Michigan);  Robert E. Maleczka (Dewitt, Michigan)
ABSTRACT A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO2CF3), or nonaflate (OSO2C4F9). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.
FILED Friday, July 12, 2002
APPL NO 10/194859
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
546/250
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US 06867305 Danishefsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S) Samuel J. Danishefsky (Englewood, New Jersey);  Shawn J. Stachel (Perkasie, New Jersey);  Chul Bom Lee (Princeton, New Jersey);  Mark D. Chappell (Noblesville, Indiana);  Zhical Wu (New York, New York)
ABSTRACT The present invention provides convergent processes for preparing epothilones, desoxyepothilones, and analogues thereof. The present invention further provides novel compositions and methods for the treatment of cancer and additionally provides methods for the treatment of cancer which has developed a multi-drug phenotype.
FILED Thursday, March 01, 2001
APPL NO 09/796959
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/204
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US 06867310 Buchwald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Stephen L. Buchwald (Newton, Massachusetts);  John P. Wolfe (Brighton, Massachusetts);  Jens Ahman (Sandwich, United Kingdom);  Malisa Troutman (Irvington, New York);  Michael Palucki (Belle Meade, New Jersey);  Ken Kamikawa (Brookline, Massachusetts);  Andre Chieffi (Somerville, Massachusetts)
ABSTRACT The present invention provides transition-metal-catalyst-based methods for the arylation and vinylation of activated methyl, methylene, and methine carbons with aryl halides, vinyl halides, and the like. The methods of the invention provide several improvements over existing methods, including the ability to synthesize efficiently and under mild conditions α-aryl and α-vinyl products from a wide range of starting materials, including ketones, esters, hydrazones, and imines. Furthermore, the methods of the invention may be used in an asymmetric sense, i.e. to produce enantiomerically-enriched chiral α-aryl and α-vinyl products.
FILED Wednesday, January 27, 1999
APPL NO 09/239024
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
549/453
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US 06867349 Ekker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Stephen C. Ekker (St. Paul, Minnesota);  Aidas Nasevicius (St. Paul, Minnesota);  Hyon Kim (Minneapolis, Minnesota);  Saulius Sumanas (Minneapolis, Minnesota)
ABSTRACT The invention provides sequence specific polynucleotide analogues and methods for determining the function of a nucleic acid of known sequence.
FILED Monday, July 30, 2001
APPL NO 09/918242
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/21
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US 06867415 Hughey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Newton Scientific, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Barbara J. Hughey (Lexington, Massachusetts);  Paul L. Skipper (Belmont, Massachusetts);  John S. Wishnok (Boston, Massachusetts);  Ruth E. Shefer (Newton, Massachusetts);  Naomi A. Fried (Oakland, California);  John T. Mehl (Westfield, New Jersey);  Steven R. Tannenbaum (Framingham, Massachusetts)
ABSTRACT An interface for introducing a non-gaseous sample as a predetermined gaseous form into an accelerator mass spectrometer which comprises a nebulizer that receives the non-gaseous sample to provide a fine spray of the sample, a converter that receives at least a portion of said fine spray and converts the desired elements to the predetermined gaseous form and a flow line that transports the predetermined gaseous form to the accelerator mass spectrometer.
FILED Thursday, August 23, 2001
APPL NO 09/938277
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/288
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US 06868221 Wood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Health Research, Inc. (Buffalo, New York)
INVENTOR(S) Leroy M. Wood (Buffalo, New York);  William R. Potter (Grand Island, New York);  Kenneth R. Weishaupt (Hamburg, New York)
ABSTRACT The present invention relates to an apparatus which includes a polypod support which includes a fiber optic supporting platform. The fiber optic supporting platform includes an opening. The apparatus further includes at least three legs forming a tripod, each of the legs having two ends, a first end being secured to the fiber optic supporting platform and the second end being adapted for attachment to the skin of the patient, a first tube having an outer diameter, a second tube having an outer diameter and an inner diameter, where the inner diameter of the second tube surrounds the outer diameter of the first tube and where the outer diameter of the second tube is slidably mounted within the opening of the fiber optic surrounding platform and a fiber optic.
FILED Thursday, May 08, 2003
APPL NO 10/434420
ART UNIT 2839 — Optics
CURRENT CPC
Optical waveguides
385/137
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Department of Defense (DOD) 

US 06865977 Kim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Robert M. Kim (Lyndhurst, New Jersey);  Stephan P. Kaiser (Oberahr, Germany);  Michael W. Selk (Rockaway, New Jersey);  James F. Zoll (Flanders, New Jersey)
ABSTRACT A protective packaging device provides mitigation of the blast effect and fragmentation of a hand grenade when the grenade is detonated. The device includes at least one protective housing assembly, formed by inner and outer nested housing members, in which the hand grenade is received, and which, in response to detonation of the grenade, retains fragments of the grenade while providing controlled release, through the mesh material, of gases formed upon detonation. A cushioning container includes a cushioning material having a plurality of open compartments therein in which a corresponding plurality of the protective housing assemblies are received.
FILED Thursday, July 10, 2003
APPL NO 10/604320
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosive-charge making
086/50
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US 06865990 Greene et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael L. Greene (Fort Washington, Maryland);  Jacob Tallman (Indian Head, Maryland)
ABSTRACT The invention comprises a device that uses a flexible material, preferably in a mostly square shape, having substantially orthogonal grooves scored into one side. An explosive charge, usually in the form of a sheet of explosives, is cut to fit the side opposite the grooves, in substantially the same shape as the grooves, without extending beyond the periphery of the flexible material. An initiating means is connected to the explosive charge so that upon initiation, the grooves focus the explosive charge so that a plurality of petals cantilevered are formed in the target material, substantially between the ends of the grooves, to define a fragment-free opening in the target material.
FILED Thursday, January 09, 2003
APPL NO 10/339256
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/309
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US 06866233 Patel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)
ASSIGNEE(S) Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S) Mehul P. Patel (Streetsboro, Ohio);  Jack M DiCocco (Broadview Heights, Ohio);  Troy Prince (Cleveland, Ohio)
ABSTRACT The present invention relates to a reconfigurable porous technology for fluid flow control system and more particularly to reconfigurable porosity fluid flow control system for vehicles such as aircraft, missiles, ground and water vehicles to improve the performance of such vehicles. The present invention further relates to a method of operating the reconfigurable fluid flow control system. In one embodiment, the present invention includes a reconfigurable porosity system for fluid flow control on the surface of an aircraft, missile, water-craft or ground vehicle comprising a porous outer skin comprising individual pores; individually addressable valves corresponding and connected to the individual pores for opening and closing the pores; and a pneumatic system for connecting the pores wherein fluid from a high pressure area of the porous outer skin can be directed to a low pressure area of the porous outer skin by opening and closing the individually addressable valves. In another embodiment, the present invention includes a method of fluid flow control using reconfigurable porosity.
FILED Friday, January 03, 2003
APPL NO 10/336113
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/204
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US 06866512 Ebersole, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Information Decision Technologies, LLC (Bedford, New Hampshire)
INVENTOR(S) John Franklin Ebersole, Jr. (Bedford, New Hampshire);  Mark Stanley Bastian (Manchester, New Hampshire)
ABSTRACT The purpose of the invention is to protect an instrumented firefighter's fire hose nozzle from shock and undesirable environmental pollutant penetration. The invention provides for doing this through the use of a rugged cover on the equipment as well as soft equipment mounts. The cover provides the instrumentation with protection from impact as well as protection from contamination by environmental pollutants. On the inside of the cover, the shock sensitive equipment is seated on an island that is mounted by one or more soft vertical posts, which protect this equipment from shock.
FILED Tuesday, August 06, 2002
APPL NO 10/213677
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Education and demonstration
434/226
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US 06866762 Gascoyne et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, University of Texas System (Austin, Texas)
INVENTOR(S) Peter Gascoyne (Bellaire, Texas);  Jon Schwartz (Sugar Land, Texas);  Jody V. Vykoukal (Houston, Texas);  Frederick F. Becker (Houston, Texas)
ABSTRACT A dielectric gate and related systems and methods for controlling fluid flow. A dielectric gate includes one or more electrodes coupled between an inlet fluid pathway and an outlet fluid pathway. The electrodes are configured to draw fluid from the inlet fluid pathway to the outlet fluid pathway in a precise manner by using dielectric forces arising from electrical signals applied to the electrodes.
FILED Thursday, December 20, 2001
APPL NO 10/028945
ART UNIT 1753 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/547
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US 06866764 Dalman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S)
ASSIGNEE(S) Michigan Molecular Institute (Midland, Michigan)
INVENTOR(S) David A. Dalman (Midland, Michigan);  Petar R. Dvornic (Midland, Michigan)
ABSTRACT An inexpensive process for depositing an electrically conductive material on selected surfaces of a dielectric substrate may be advantageously employed in the manufacture of printed wiring boards having high quality, high density, fine-line circuitry, thereby allowing miniaturization of electronic components and/or increased interconnect capacity. The process may also be used for providing conductive pathways between opposite sides of a dielectric substrate and in decorative metallization applications. The process includes steps of depositing a radially-layered dendritic copolymer on selected surfaces of a dielectric substrate; cross-linking the radially-layered dendritic copolymer to form a dendritic polymer network; sorbing metal cations into the cross-linked dendritic polymer network; reducing the metal cations to form a nanocomposite composition exhibiting adequate surface electrical conductivity for electroplating; and electroplating a metal onto the nanocomposite composition to form an electrically conductive deposit.
FILED Thursday, February 21, 2002
APPL NO 10/080295
ART UNIT 1753 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/125
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US 06867281 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brett D. Martin (Washington, District of Columbia);  Ranganathan Shashidhar (Woodbridge, Virginia);  Nikolay Nikolov (Woodbridge, Virginia);  John C. Mastrangelo (Alexandria, Virginia)
ABSTRACT A compound comprising the formula:
wherein R1 is a fluorinated organic group and R2 and R3 are independently selected organic groups. A compound comprising the formula:
wherein R1 is a fluorinated organic group and R2 and R3 are independently selected organic groups.
FILED Wednesday, March 26, 2003
APPL NO 10/396443
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
528/373
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US 06867289 Gorenstein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas Systems (Austin, Texas)
INVENTOR(S) David G. Gorenstein (Houston, Texas);  Bruce A. Luxon (Galveston, Texas);  Norbert Herzog (Friendswood, Texas);  Judy Aronson (Galveston, Texas)
ABSTRACT This invention generally relates the generation of aptamers and to the use of aptamers as diagnostic and therapeutic agents. More particularly, the present invention relates to methods using combinatorial chemistry to prepare aptamers having controlled thiophosphate replacement in the phosphate backbone for improved binding efficiencies to a target and to RNA and/or DNA products having novel nucleotide sequences and enhanced target binding efficacies.
FILED Monday, October 25, 1999
APPL NO 09/425804
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
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US 06867304 Tan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Loon-Seng Tan (Centerville, Ohio);  Ramamurthi Kannan (Cincinnati, Ohio)
ABSTRACT Provided are new TPA chromophores of the formula:
wherein R is an alkyl group having 1 to 20 carbon atoms and Q is —C6H13, —CH2—C6H5, or —C6H11.
FILED Monday, February 23, 2004
APPL NO 10/784312
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/156
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US 06867443 Liu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Chang Liu (Champaign, Illinois);  Ming Zhang (Urbana, Illinois);  David Andrew Bullen (Urbana, Illinois)
ABSTRACT A microfabricated probe array for nanolithography and process for designing and fabricating the probe array. The probe array consists of individual probes that can be moved independently using thermal bimetallic actuation or electrostatic actuation methods. The probe array can be used to produce traces of diffusively transferred chemicals on the substrate with sub-1 micrometer resolution, and can function as an arrayed scanning probe microscope for subsequent reading and variation of transferred patterns.
FILED Monday, August 25, 2003
APPL NO 10/647724
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/226
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US 06867444 Hughes
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Harold L. Hughes (West River, Maryland)
ABSTRACT A semiconductor substrate incorporating a neutron conversion layer (such as boron-10) that is sensitive enough to permit the counting of single neutron events. The substrate includes an active semiconductor device layer, a base substrate, an insulating layer provided between the active semiconductor device layer and the base substrate, and a neutron conversion layer provided between the active semiconductor device layer and the base substrate. The neutron conversion layer is located within the insulating layer, between the insulating layer and the base substrate or between the active semiconductive device layer and the insulating layer. A barrier layer is provided between at least one of the neutron conversion layer and the active semiconductor device layer and the neutron conversion layer and the base substrate to prevent diffusion of the neutron conversion material provided in the neutron conversion layer. Further, a plurality of trenches may be formed in the active semiconductor device layer. In such a case, a trench neutron conversion layer is formed in at least one of the trenches to improve device sensitivity.
FILED Monday, October 20, 2003
APPL NO 10/693846
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/252
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US 06867538 Adachi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Chihaya Adachi (Hokkaido, Japan);  Marc A. Baldo (Princeton, New Jersey);  Stephen R. Forrest (Princeton, New Jersey)
ABSTRACT Phosphorescent OLEDs having a double doped-layer structure wherein the OLEDs include a hole transporting layer (HTL) having a phosphorescent material doped therein, and an electron transporting layer (ETL) having the same phosphorescent material doped therein. Typically, these phosphorescent OLEDs have an anode, a first HTL over the anode, a second HTL that is doped with a phosphorescent material over the first HTL, a first ETL that is doped with a phosphorescent material over the second HTL, a second ETL over the first ETL, and a cathode over the second ETL. These phosphorescent OLEDs preferably include blue phosphorescent OLEDs with high efficiency levels.
FILED Friday, March 01, 2002
APPL NO 10/087417
ART UNIT 2882 — Optics
CURRENT CPC
Electric lamp and discharge devices
313/503
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US 06867681 Bower et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) QorTek, Inc. (Williamsport, Pennsylvania)
INVENTOR(S) Bruce Bower (Williamsport, Pennsylvania);  Gareth Knowles (Williamsport, Pennsylvania)
ABSTRACT A current control device is described wherein a pressure conduction composite is compressed and decompressed to alter its conductivity and thereby current conduction through the device. The pressure conduction composite is composed of a nonconductive matrix, a conductive filler, and an additive. The invention consists of electrodes and pressure plates contacting the composite. Electrically activated actuators apply a force onto pressures plates. Actuators are composed of a piezoelectric, piezoceramic, electrostrictive, magnetostrictive, and shape memory materials, capable of extending and/or contracting thereby altering pressure and consequently resistivity within the composite. In an alternate embodiment, two or more current control devices are electrically coupled parallel to increase power handling.
FILED Tuesday, April 27, 2004
APPL NO 10/832705
ART UNIT 2832 — Semiconductors/Memory
CURRENT CPC
Electrical resistors
338/47
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US 06867727 Mitra
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Atindra Mitra (Kettering, Ohio)
ABSTRACT A system-of-systems avionics architecture that is compatible with futuristic multi-function multi-platform sensor applications. The method and device of the invention is based on localized “adaptive” waveform and spectrum allocation for ultra-wideband radio frequency and microwave signals. The invention includes a plurality of system platforms with each platform comprising a common radio frequency front end for receiving ultra-wideband signals, a common radio frequency back end for transmitting ultra-wideband signals and a plurality of sensors for exchanging data between platforms.
FILED Monday, March 01, 2004
APPL NO 10/794544
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/59
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US 06867728 Hanna et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Craig A. Hanna (Vestal, New York);  James A. Johnson (Newark Valley, New York)
ABSTRACT Signals-of-interest are identified by distinguishing such signals from signals constituting environmental or internal receiver noise. A received signal is rapidly sampled in order to set a dynamic, system threshold. Signals above the threshold constitute signals-of-interest.
FILED Thursday, November 06, 2003
APPL NO 10/701473
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/91
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867737 Ryken, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Marvin L. Ryken, Jr. (Oxnard, California);  Albert F. Davis (Ventura, California)
ABSTRACT A GPS conical shaped microstrip antenna array which receives GPS data and which is adapted for use on weapons systems such as a missile or smart bomb. The microstrip antenna array has a center frequency of 1.575 GHz, a frequency bandwidth of twenty megahertz and provides for right hand circular polarization. The microstrip antenna includes a four aligned copper antenna elements which have a square shape, and a copper etched feed network which provides for a signal phase shift of ninety degrees resulting in right hand circular polarization of each of the four aligned antenna elements.
FILED Wednesday, August 27, 2003
APPL NO 10/648715
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/700.MS0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867742 Irion, II et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) James M. Irion, II (Plano, Texas);  Nicholas A. Schuneman (Dallas, Texas);  Richard E. Hodges (Corona, California)
ABSTRACT An antenna apparatus (10) includes an antenna element (12, 412, 512) that has conductive material with a recess therein. The recess includes a balun hole (36, 536), and a tapered slot (37, 537) communicating at its narrow end with the balun hole. The balun hole is approximately rectangular, has a peripheral edge defined by conductive material, and contains air. The tapered slot has a shape which is optimized as a function of factors that include the balun hole design. Each slot edge follows a predetermined curve other than a first-order exponential curve.
FILED Friday, December 14, 2001
APPL NO 10/023229
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/767
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867753 Chinthammit et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Winyu Chinthammit (Seattle, Washington);  Eric Seibel (Seattle, Washington);  Thomas A Furness, III (Seattle, Washington)
ABSTRACT A virtual image is registered among a perceived real world background. Tracking light is scanned into the real world environment, which includes at least one detector pair. A first time and a second time at which the tracking light impinges on the first detector is detected, in which the first time and second time occurs within adjacent scan lines. A time at which a horizontal scan line edge (e.g., beginning of scan line or end of scan line) is encountered is derived as occurring one half way between the first time and the second time. The horizontal location of the first detector then is determined within a specific scan line inferring the scan line edge time. The vertical location of the detector is determined within a scan frame by measuring time duration using the beginning of the frame. By determining a location independently from the temporal resolution of the augmented imaging system, the temporal location of the detector is identified to a sub-pixel/sub-line precision. The augmented image is registered either to a 3D real world spatial coordinate system or to a time domain coordinate system based upon tracked position and orientation of the user.
FILED Monday, October 28, 2002
APPL NO 10/281517
ART UNIT 2673 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/8
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US 06867854 Wapner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Phillip G. Wapner (Palmdale, California);  Wesley P. Hoffman (Palmdale, California)
ABSTRACT A liquid to solid material surface contact angle measurement system operating by way of detecting a transition in the behavior of a liquid sample with the solid material in a changing angular confinement environment along with use of a mathematical algorithm to then determine contact angle. Measurement of the angle at which the tested liquid transitions between apparent wetting and apparent non-wetting behavior, regardless of whether the liquid and solid material are truly classified as wetting or non-wetting, provides a measurement from which disclosed mathematical algorithms can predict the surface wetting characteristics of the liquid on the solid material. Automated performance of the confinement environment measurement and examples are included.
FILED Thursday, January 02, 2003
APPL NO 10/335660
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/150
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US 06867904 Ng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Willie W. Ng (Agoura Hills, California);  Daniel Yap (Newbury Park, California)
ABSTRACT An apparatus containing an integrated optical circuit that enhances phase stability of the injection-locking process of two slave lasers. The integrated optical circuit helps to reduce phase noise by keeping environmental or mechanical perturbations uniform everywhere on that circuit. Also, the integrated optical circuit provides connections for additional components to be coupled, which can monitor and control the performance characteristics of the integrated optical circuit and the injection-locking process.
FILED Wednesday, April 16, 2003
APPL NO 10/417020
ART UNIT 2874 — Optics
CURRENT CPC
Optical: Systems and elements
359/332
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US 06868042 Christman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Russell A. Christman (Old Lyme, Connecticut);  Mohamed H. Ahmed (Wakefield, Rhode Island)
ABSTRACT A data-based technique is disclosed that defines the amplitude and phase of acoustic signals for detection as they propagate across an array of sensor elements for each array incident angle of interest. The definitions of the acoustic signals are then used to constrain adaptive noise suppression operating routines from canceling desired acoustic representative of desired incident direction detector. The data-based technique of defining acoustic signals also leads to a greater reduction of noise in directions where signal is not present. The use of this technique within an adaptive-array-beamforming-processor, and more particularly in connection with the provision of data-based steering vectors therefor, results in an improvement in the ability to detect acoustic signals imbedded in noise.
FILED Thursday, August 08, 2002
APPL NO 10/214528
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/119
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06868107 Vurgaftman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Igor Vurgaftman (Pikesville, Maryland);  Jerry Meyer (Catonsville, Maryland)
ABSTRACT A method for calculating the beam quality and output wavelength spectrum of a photonic crystal distributed feedback laser includes the steps of calculating at least two coupling coefficients and forming a characteristic matrix; repeating the following steps at spaced increments of time until a steady state solution is reached: repeating the following steps for one of the incremental cavity lengths: calculating a gain change and a modal refractive index change for the laser waveguide structure for one incremental stripe width; calculating a spontaneous emission term for the gain change; calculating a gain roll-off term for the gain change; applying the gain change, the modal refractive index change, the spontaneous emission term, and the gain roll-off term to at least two forward-propagating beams and at least two backward-propagating beams for the one incremental stripe width; performing a Fourier transformation with respect to the one incremental stripe width to yield a plurality of diffraction terms; adding the diffraction terms to the characteristic matrix; propagating the two forward-propagating beams by the incremental cavity length from a first section to a succeeding and adjacent second section with the characteristic matrix; propagating the two backward-propagating beams by the incremental cavity length from the second section to the first section with the characteristic matrix; performing an inverse Fourier transformation with respect to the stripe width; and applying at least one boundary condition to a facet of the laser configuration for each time increment. The steady-state solution is used as the basis for evaluating the beam quality and output wavelength spectrum corresponding to the design parameters, the additional design parameters, and the photonic crystal geometry of the laser configuration. The invention provides scientists with an approach to designing and building lasers that eliminates much of the time and resources otherwise needed in the building and testing of unsuccessful designs.
FILED Friday, March 07, 2003
APPL NO 10/390255
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/96
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06868197 Daniels
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Danny Daniels (Panama City, Florida)
ABSTRACT An interface assures high-speed transmission of optical data between submerged vessels. First and second vessels have pressure hulls and have a first plate transparent to optical data on the pressure hull of the first vessel and a second plate transparent to optical data on the pressure hull of the second vessel. A first optical transceiver in the first vessel is adjacent to the first transparent plate, and a second optical transceiver in the second vessel is adjacent to the second transparent plate. A layer of water between the first plate and the second plate is optically transparent to optical data to allow the first optical transceiver and the second optical transceiver to transmit and receive optical data through the first transparent plate, the water layer, and the second transparent plate.
FILED Tuesday, January 28, 2003
APPL NO 10/354708
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/15
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06868360 Olstad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) William D. Olstad (Panama City, Florida);  Dennis G. Gallagher (Panama City, Florida)
ABSTRACT A system and method indicate the direction faced by an operator. A waterproof housing has a mounting mechanism to engage a part of a headgear worn by an operator to position the housing in a portion of the operator's forward field of view. A two-axis gimbal mechanism is inside the waterproof housing and has a protective housing connected to the waterproof housing. The protective housing contains ring structure coupled to two orthogonal axis structures. A magnetic field sensor module is mounted on one of the axis structures and provides magnetic field data signals representative of the direction faced by the operator. An optical element has a wide field of view to transmit compass data images representative of the magnetic field data signals to the eyes of the operator.
FILED Monday, November 03, 2003
APPL NO 10/699426
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/150
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Department of Energy (DOE) 

US 06865939 Kirby et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Naitonal Laboratories (Livermore, California)
INVENTOR(S) Brian J. Kirby (San Francisco, California);  Timothy Jon Shepodd (Livermore, California)
ABSTRACT A method for surface modification of microchannels and capillaries. The method produces a chemically inert surface having a lowered surface free energy and improved frictional properties by attaching a fluorinated alkane group to the surface. The coating is produced by hydrolysis of a silane agent that is functionalized with either alkoxy or chloro ligands and an uncharged C3-C10 fluorinated alkane chain. It has been found that the extent of surface coverage can be controlled by controlling the contact time from a minimum of about 2 minutes to a maximum of 120 minutes for complete surface coverage.
FILED Monday, September 16, 2002
APPL NO 10/245224
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/253
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US 06866560 Follstaedt et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David M. Follstaedt (Albuquerque, New Mexico);  Michael P. Moran (Rio Rancho, New Mexico)
ABSTRACT A method for thinning (such as in grinding and polishing) a material surface using an instrument means for moving an article with a discontinuous surface with an abrasive material dispersed between the material surface and the discontinuous surface where the discontinuous surface of the moving article provides an efficient means for maintaining contact of the abrasive with the material surface. When used to dimple specimens for microscopy analysis, a wheel with a surface that has been modified to produce a uniform or random discontinuous surface significantly improves the speed of the dimpling process without loss of quality of finish.
FILED Thursday, January 09, 2003
APPL NO 10/339832
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Abrading
451/28
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06866759 Miles et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robin R. Miles (Danville, California);  Amy Wei-Yun Wang (Oakland, California);  Raymond P. Mariella, Jr. (Danville, California)
ABSTRACT A fluidic channel patterned with a series of thin-film electrodes makes it possible to move and concentrate DNA in a fluid passing through the fluidic channel. The DNA has an inherent negative charge and by applying a voltage between adjacent electrodes the DNA is caused to move. By using a series of electrodes, when one electrode voltage or charge is made negative with respect to adjacent electrodes, the DNA is repelled away from this electrode and attached to a positive charged electrode of the series. By sequentially making the next electrode of the series negative, the DNA can be moved to and concentrated over the remaining positive electrodes.
FILED Wednesday, December 13, 2000
APPL NO 09/738462
ART UNIT 1753 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/457
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US 06866768 Bradford et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Donald R Bradford (Underwood, Washington);  Robert J. Barnett (Goldendale, Washington);  Michael B. Mezner (Sandy, Oregon)
ABSTRACT Electrolysis of alumina dissolved in a molten salt electrolyte employing inert anode and cathodes, the anode having a box shape with slots for the cathodes.
FILED Friday, March 14, 2003
APPL NO 10/387602
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/376
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US 06866886 Knowles et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Shawn D. Knowles (Saint Francis, Minnesota);  David J. Senor (West Richland, Washington);  Steven V. Forbes (Burbank, Washington);  Roger N. Johnson (Richland, Washington);  Glenn W. Hollenberg (Kennewick, Washington)
ABSTRACT A method for forming a diffusion coating on the interior of surface of a hollow object wherein a filament, extending through a hollow object and adjacent to the interior surface of the object, is provided, with a coating material, in a vacuum. An electrical current is then applied to the filament to resistively heat the filament to a temperature sufficient to transfer the coating material from the filament to the interior surface of the object. The filament is electrically isolated from the object while the filament is being resistively heated. Preferably, the filament is provided as a tungsten filament or molybdenum filament. Preferably, the coating materials are selected from the group consisting of Ag, Al, As, Au, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Dy, Er, Eu, Fe, Ga, Ge, Hg, In, K, Li, Mg, Mn, Na, Ni P, Pb, Pd, Pr, S, Sb, Sc, Se, Si, Sn, Sr, Te, Tl, Y, Yb, Zn, and combinations thereof. The invention additionally allows for the formation of nitrides, hydrides, or carbides of all the possible coating materials, where such compounds exist, by providing a partial pressure of nitrogen, hydrogen, hydrocarbons, or combination thereof, within the vacuum.
FILED Wednesday, April 02, 2003
APPL NO 10/406766
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating processes
427/237
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US 06866897 Wang et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Hongyu Wang (Hockessin, Delaware);  David Joseph Mitchell (Niskayuna, New York);  Yuk-Chiu Lau (Ballston Lake, New York);  Arnold Thomas Henry (Gloversville, New York)
ABSTRACT A method for manufacturing an article for use in a high-temperature environment, and an article for use in such an environment, are presented. The method comprises providing a substrate; selecting a desired vertical crack density for a protective coating to be deposited on the substrate; providing a powder, wherein the powder has a size range selected to provide a coating having the desired vertical crack density; and applying a thermal-sprayed coating to the substrate, the coating having the desired vertical crack density, wherein the powder is used as a raw material for the coating.
FILED Monday, September 30, 2002
APPL NO 10/065260
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating processes
427/454
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867042 Waldo
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Los Alamos, New Mexico)
INVENTOR(S) Geoffrey S. Waldo (Espanola, New Mexico)
ABSTRACT A solubility reporter for measuring a protein's solubility in vivo or in vitro is described. The reporter, which can be used in a single living cell, gives a specific signal suitable for determining whether the cell bears a soluble version of the protein of interest. A pool of random mutants of an arbitrary protein, generated using error-prone in vitro recombination, may also be screened for more soluble versions using the reporter, and these versions may be recombined to yield variants having further-enhanced solubility. The method of the present invention includes “irrational” (random mutagenesis) methods, which do not require a priori knowledge of the three-dimensional structure of the protein of interest. Multiple sequences of mutation/genetic recombination and selection for improved solubility are demonstrated to yield versions of the protein which display enhanced solubility.
FILED Monday, August 12, 2002
APPL NO 10/217995
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/440
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867149 Bajt et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) EUV Limited Liability Corporation (Santa Clara, California)
INVENTOR(S) Sasa Bajt (Livermore, California);  Stephen P. Vernon (Pleasanton, California)
ABSTRACT The chemical composition of thin films is modulated during their growth. A computer code has been developed to design specific processes for producing a desired chemical composition for various deposition geometries. Good agreement between theoretical and experimental results was achieved.
FILED Friday, September 27, 2002
APPL NO 10/256324
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Semiconductor device manufacturing: Process
438/763
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867419 Tajima
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Toshiki Tajima (Alamo, California)
ABSTRACT A laser driven compact ion source including a light source that produces an energy pulse, a light source guide that guides the energy pulse to a target and produces an ion beam. The ion beam is transported to a desired destination.
FILED Friday, March 29, 2002
APPL NO 10/112451
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/423.P00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867420 Mathies et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard A. Mathies (Moraga, California);  Toshihiro Kamei (Emeryville, California);  James R. Scherer (Richmond, California);  Robert A. Street (Palo Alto, California)
ABSTRACT A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated components, light collection, optical fluorescence filtering, and an amorphous a-Si:H detector for detection. The collection of light is accomplished with proximity gathering and/or a micro-lens system. Optical filtering is accomplished by integrated optical filters. Detection is accomplished utilizing a-Si:H detectors.
FILED Thursday, October 10, 2002
APPL NO 10/269138
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/458.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867435 Sweatt et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) William C. Sweatt (Albuquerque, New Mexico);  Todd R. Christenson (Albuquerque, New Mexico)
ABSTRACT Microoptical systems with clear aperture of about one millimeter or less are fabricated from a layer of photoresist using a lithographic process to define the optical elements. A deep X-ray source is typically used to expose the photoresist. Exposure and development of the photoresist layer can produce planar, cylindrical, and radially symmetric micro-scale optical elements, comprising lenses, mirrors, apertures, diffractive elements, and prisms, monolithically formed on a common substrate with the mutual optical alignment required to provide the desired system functionality. Optical alignment can be controlled to better than one micron accuracy. Appropriate combinations of structure and materials enable optical designs that include corrections for chromatic and other optical aberrations. The developed photoresist can be used as the basis for a molding operation to produce microoptical systems made of a range of optical materials. Finally, very complex microoptical systems can be made with as few as three lithographic exposures.
FILED Wednesday, January 15, 2003
APPL NO 10/345732
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/98
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867536 Srivastava et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Alok Srivastava (Niskayuna, New York);  Holly Comanzo (Niskayuna, New York);  Venkatesan Manivannan (Recford, New York);  Anant Achyut Setlur (Niskayuna, New York)
ABSTRACT A fluorescent lamp including a phosphor layer including Sr4Al14O25:Eu2+ (SAE) and at least one of each of a red, green and blue emitting phosphor. The phosphor layer can optionally include an additional, deep red phosphor and a yellow emitting phosphor. The resulting lamp will exhibit a white light having a color rendering index of 90 or higher with a correlated color temperature of from 2500 to 10000 Kelvin. The use of SAE in phosphor blends of lamps results in high CRI light sources with increased stability and acceptable lumen maintenance over, the course of the lamp life.
FILED Thursday, December 12, 2002
APPL NO 10/317372
ART UNIT 2879 — Optics
CURRENT CPC
Electric lamp and discharge devices
313/487
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867644 Taubman
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Matthew S. Taubman (Richland, Washington)
ABSTRACT Among the embodiments of the present invention is an apparatus that includes a transistor (30), a servo device (40), and a current source (50). The servo device (40) is operable to provide a common base mode of operation of the transistor (30) by maintaining an approximately constant voltage level at the transistor base (32b). The current source (150) is operable to provide a bias current to the transistor (30). A first device (24) provides an input signal to an electrical node (70) positioned between the emitter (32e) of the transistor (30) and the current source (50). A second device (26) receives an output signal from the collector (32c) of the transistor (30).
FILED Friday, September 27, 2002
APPL NO 10/256651
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Miscellaneous active electrical nonlinear devices, circuits, and systems
327/563
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US 06868035 West
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Bechtel BWXT Idaho, LCC (Idaho Falls, Idaho)
INVENTOR(S) Phillip B. West (Idaho Falls, Idaho)
ABSTRACT A method and apparatus suitable for coupling seismic or other downhole sensors to a borehole wall in high temperature and pressure environments. In one embodiment, one or more metal bellows mounted to a sensor module are inflated to clamp the sensor module within the borehole and couple an associated seismic sensor to a borehole wall. Once the sensing operation is complete, the bellows are deflated and the sensor module is unclamped by deflation of the metal bellows. In a further embodiment, a magnetic drive pump in a pump module is used to supply fluid pressure for inflating the metal bellows using borehole fluid or fluid from a reservoir. The pump includes a magnetic drive motor configured with a rotor assembly to be exposed to borehole fluid pressure including a rotatable armature for driving an impeller and an associated coil under control of electronics isolated from borehole pressure.
FILED Tuesday, November 05, 2002
APPL NO 10/288963
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/25
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 06867166 Yang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Ralph T. Yang (Ann Arbor, Michigan);  Joel Padin (Ann Arbor, Michigan);  Salil U. Rege (Ann Arbor, Michigan)
ABSTRACT The invention provides novel adsorbents for use in the separation of unsaturated hydrocarbons from a mixture of gases containing such hydrocarbons. The preferred adsorbents comprise metal compounds supported on high surface area carriers. The adsorbents of the invention are usable in pressure swing adsorption or temperature swing adsorption processes.
FILED Monday, February 25, 2002
APPL NO 10/082550
ART UNIT 1754 — AI & Simulation/Modeling
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/401
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867274 Maughon et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Bob R. Maughon (Midland, Michigan);  Takeharu Morita (Osaka, Japan);  Robert H. Grubbs (South Pasadena, California)
ABSTRACT The present invention relates to telechelic polymers having crosslinkable end groups of the formula
and methods for preparing the same wherein n is an integer;
is an alkadienyl group; Y is an alkyl group; and Z is crosslinkable end group. In general, the inventive synthesis involves reacting a functionalized chain transfer agent having crosslinkable ends with a cycloalkene in the presence of a ruthenium or osmium catalyst of the formula
wherein: M is ruthenium or osmium; X and X1 are independently any anionic ligand; L and L1 are any neutral electron donor ligand;
R and R1 are each hydrogen or a substituted or unsubstituted substituent wherein the substituent is selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C1-C20 alkynyl, aryl, C1-C20 carboxylate, C1-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthio, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl. In another aspect of the invention, methods for controlling the molecular weight of the resulting telechelic polymer are also presented.
FILED Tuesday, May 21, 2002
APPL NO 10/151757
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
526/264
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867302 Smith, III et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Milton R. Smith, III (East Lansing, Michigan);  Robert E. Maleczka (Dewitt, Michigan)
ABSTRACT A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO2CF3), or nonaflate (OSO2C4F9). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.
FILED Friday, July 12, 2002
APPL NO 10/194859
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
546/250
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867305 Danishefsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S) Samuel J. Danishefsky (Englewood, New Jersey);  Shawn J. Stachel (Perkasie, New Jersey);  Chul Bom Lee (Princeton, New Jersey);  Mark D. Chappell (Noblesville, Indiana);  Zhical Wu (New York, New York)
ABSTRACT The present invention provides convergent processes for preparing epothilones, desoxyepothilones, and analogues thereof. The present invention further provides novel compositions and methods for the treatment of cancer and additionally provides methods for the treatment of cancer which has developed a multi-drug phenotype.
FILED Thursday, March 01, 2001
APPL NO 09/796959
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/204
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867310 Buchwald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Stephen L. Buchwald (Newton, Massachusetts);  John P. Wolfe (Brighton, Massachusetts);  Jens Ahman (Sandwich, United Kingdom);  Malisa Troutman (Irvington, New York);  Michael Palucki (Belle Meade, New Jersey);  Ken Kamikawa (Brookline, Massachusetts);  Andre Chieffi (Somerville, Massachusetts)
ABSTRACT The present invention provides transition-metal-catalyst-based methods for the arylation and vinylation of activated methyl, methylene, and methine carbons with aryl halides, vinyl halides, and the like. The methods of the invention provide several improvements over existing methods, including the ability to synthesize efficiently and under mild conditions α-aryl and α-vinyl products from a wide range of starting materials, including ketones, esters, hydrazones, and imines. Furthermore, the methods of the invention may be used in an asymmetric sense, i.e. to produce enantiomerically-enriched chiral α-aryl and α-vinyl products.
FILED Wednesday, January 27, 1999
APPL NO 09/239024
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
549/453
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867323 Denmark et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Scott E. Denmark (Champaign, Illinois);  Jun Young Choi (Taejon, South Korea);  Daniel Wehrli (Zurich, Switzerland);  Zhicai Wu (New York, New York);  Luc Neuville (Urbana, Illinois);  Weitao Pan (Urbana, Illinois);  Ramzi F. Sweis (Champaign, Illinois);  Zhigang Wang (Montreal, Canada);  Shyh-Ming Yang (Urbana, Illinois)
ABSTRACT Improved methods for generating a —C—C— bond by cross-coupling of a transferable group with an acceptor group. The transferable group is a substituent of an organosilicon nucleophile and the acceptor group is provided as an organic electrophile. The reaction is catalyzed by a Group 10 transition metal complex (e.g., Ni, Pt or Pd), particularly by a palladium complex. Certain methods of this invention use improved organosilicon nucleophiles which are readily prepared, can give high product yields and exhibit high stereoselectivity. Methods of this invention employ activating ions such as halides, hydroxide, hydride and silyloxides. In specific embodiments, organosilicon nucleophilic reagents of this invention include siloxanes, particularly cyclic siloxanes. The combination of the cross-coupling reactions of this invention with ring-closing metathesis, hydrosilylation and intramolecular hydrosilylation reactions provide useful synthetic strategies that have wide application.
FILED Wednesday, June 06, 2001
APPL NO 09/875777
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
560/96
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867415 Hughey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Newton Scientific, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Barbara J. Hughey (Lexington, Massachusetts);  Paul L. Skipper (Belmont, Massachusetts);  John S. Wishnok (Boston, Massachusetts);  Ruth E. Shefer (Newton, Massachusetts);  Naomi A. Fried (Oakland, California);  John T. Mehl (Westfield, New Jersey);  Steven R. Tannenbaum (Framingham, Massachusetts)
ABSTRACT An interface for introducing a non-gaseous sample as a predetermined gaseous form into an accelerator mass spectrometer which comprises a nebulizer that receives the non-gaseous sample to provide a fine spray of the sample, a converter that receives at least a portion of said fine spray and converts the desired elements to the predetermined gaseous form and a flow line that transports the predetermined gaseous form to the accelerator mass spectrometer.
FILED Thursday, August 23, 2001
APPL NO 09/938277
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/288
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867656 Hajimiri et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Seyed-Ali Hajimiri (Pasadena, California);  Hui Wu (Pasadena, California)
ABSTRACT A system for generating in-phase and quadrature phase signals is provided. The system includes a first and a second differential output, such as from a sinusoidal oscillator. A first injection-locked frequency divider, such as one that uses an LC oscillator in conjunction with cross-coupled transistors, receives the first differential output and generates a in-phase or in-phase output. A second injection-locked frequency divider receives the second differential output and generates a quadrature phase output.
FILED Tuesday, June 17, 2003
APPL NO 10/463264
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/45
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06868099 Walker et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Thad G. Walker (Madison, Wisconsin);  Bien Chann (Madison, Wisconsin);  Ian A. Nelson (Madison, Wisconsin)
ABSTRACT A high power diode laser system utilizes an external cavity to narrow the spectral width of a high power multimode diode laser to change the output power normally produced by the diode from a broad spectrum to a very narrow spectrum. The power output of the laser system is concentrated over a narrow spectral range which falls within the useable range for particular applications, such as optical pumping of noble gas samples for magnetic resonance imaging. The output of the diode is received by a collimating element which directs the light on a beam path to a diffraction grating which is oriented at an angle to the incident beam. A portion of the beam may be directed from the diffraction grating to provide useable output light, and a portion of the light incident on the grating is directed back to be focused on the diode to provide feedback to cause the diode to preferentially lase at the wavelength of the light that is fed back. A polarization rotation element may be used to orient the polarization of the light passing through it to control the amount of feedback light.
FILED Friday, November 03, 2000
APPL NO 09/706088
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/20
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 06866098 Arndt et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) G. Dickey Arndt (Friendswood, Texas);  James R. Carl (Houston, Texas);  Kent A. Byerly (Seabrook, Texas);  B. Jon Amini (Houston, Texas)
ABSTRACT System and methods for transmitting and receiving electromagnetic pulses through a geological formation. A preferably programmable transmitter having an all-digital portion in a preferred embodiment may be operated at frequencies below 1 MHz without loss of target resolution by transmitting and over sampling received long PN codes. A gated and stored portion of the received signal may be correlated with the PN code to determine distances of interfaces within the geological formation, such as the distance of a water interfaces from a wellbore. The received signal is oversampled preferably at rates such as five to fifty times as high as a carrier frequency. In one method of the invention, an oil well with multiple production zones may be kept in production by detecting an approaching water front in one of the production zones and shutting down that particular production zone thereby permitting the remaining production zones to continue operating.
FILED Wednesday, October 30, 2002
APPL NO 10/288799
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Wells
166/249
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06866733 Denham et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Jerry Denham (San Diego, California);  Robert A. Dichiara, Jr. (Carlsbad, California);  Vann Heng (Buena Park, California);  Leanne L. Lehman (Laguna Niguel, California);  David Zorger (Costa Mesa, California)
ABSTRACT A flexible insulation blanket having a ceramic matrix composite (CMC) outer layer, and a method of producing a flexible insulation blanket having a smooth, aerodynamically suitable, outer surface by infiltrating ceramic material within the outer ceramic fabric layer of the flexible insulation blanket and curing the ceramic material to form a CMC layer. The CMC layer is cured while the blanket is under compression such that the resulting CMC layer has a smooth surface.
FILED Tuesday, July 01, 2003
APPL NO 10/611493
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/89.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06866752 Schramm
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Harry F. Schramm (Winchester, Tennessee)
ABSTRACT A method for providing an ultra thin electrical circuit integral with a portion of a surface of an object, including using a focal Vacuum Arc Vapor Deposition device having a chamber, a nozzle and a nozzle seal, depressing the nozzle seal against the portion of the object surface to create an airtight compartment in the chamber and depositing one or more ultra thin film layer(s) only on the portion of the surface of the object, the layers being of distinct patterns such that they form the circuit.
FILED Thursday, August 23, 2001
APPL NO 09/962704
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/192.380
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867040 Helmstetter et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Charles E. Helmstetter (Satellite Beach, Florida);  Maureen Thornton (Melbourne, Florida);  Steve Gonda (Houston, Texas)
ABSTRACT Apparatus and methods are directed to a perfusion culture system in which a rotating bioreactor is used to grow cells in a liquid culture medium, while these cells are attached to an adhesive-treated porous surface. As a result of this arrangement and its rotation, the attached cells divide, with one cell remaining attached to the substrate, while the other cell, a newborn cell is released. These newborn cells are of approximately the same age, that are collected upon leaving the bioreactor. The populations of newborn cells collected are of synchronous and are minimally, if at all, disturbed metabolically.
FILED Monday, February 24, 2003
APPL NO 10/373130
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/376
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867533 Su et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Ji Su (Highland Park, New Jersey);  Joycelyn S. Harrison (Hampton, Virginia)
ABSTRACT An electrostrictive polymer actuator comprises an electrostrictive polymer with a tailorable Poisson's ratio. The electrostrictive polymer is electroded on its upper and lower surfaces and bonded to an upper material layer. The assembly is rolled tightly and capped at its ends. In a membrane structure having a membrane, a supporting frame and a plurality of threads connecting the membrane to the frame, an actuator can be integrated into one or more of the plurality of threads. The electrostrictive polymer actuator displaces along its longitudinal axis, thereby affecting movement of the membrane surface.
FILED Monday, October 23, 2000
APPL NO 09/696527
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/328
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 06866858 Nolen et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) BioSensory, Inc. (Willimantic, Connecticut);  Bedoukian Research, Inc. (Danbury, Connecticut);  The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Jim A. Nolen (W. Greenwich, Rhode Island);  Robert H. Bedoukian (West Redding, Connecticut);  Daniel L. Kline (Gainesville, Florida)
ABSTRACT 1-Alkyn-3-ol compounds of the formula:
where R1 is a saturated aliphatic hydrocarbon group containing from 1 to about 12 carbon atoms, and R2 is a hydrogen, are effective attractants for mosquitoes.
FILED Thursday, December 28, 2000
APPL NO 09/752704
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/406
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06867350 Ferl et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Robert J. Ferl (Gainesville, Florida);  Paul C. Sehnke (Gainesville, Florida);  Hwa Jee Chung (Seoul, South Korea);  Ke Wu (Gainesville, Florida);  L. Curtis Hannah (Gainesville, Florida)
ABSTRACT The subject invention concerns materials and methods for enhancing starch production in plants. Starch production is enhanced, relative to levels observed in wildtype or control plants, by reduction of the plant 14-3-3 protein(s) which subsequently results in increased accumulation of starch in the plant. In one embodiment, the 14-3-3 protein expression is reduced using polynucleotides that are antisense to the 14-3-3 gene sequences expressed in the plant. In another embodiment, the 14-3-3 protein expression is reduced by “knockout” of a 14-3-3 gene or gene sequences. The subject invention also pertains to transformed and transgenic plants that have polynucleotides that are antisense to the 14-3-3 gene sequences expressed in the plant, wherein the transformed and transgenic plants exhibit enhanced starch production. The subject invention also pertains to “knockout” plants in which the normal functional 14-3-3 gene in the plant is deleted or replaced with a non-functional form of the gene. The subject invention also concerns the “antisense” polynucleotides of the invention that when introduced into a plant cell can function to effectively reduce expression of the 14-3-3 proteins in a plant.
FILED Thursday, May 17, 2001
APPL NO 09/859822
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/284
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 06868110 Phelts et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Robert Eric Phelts (Stanford, California);  Per Enge (Mountain View, California)
ABSTRACT A multipath mitigation method consists of locating a multipath-invariant (MPI) point of an ideal autocorrelation function and measuring the distance between the MPI point and DLL. The same MPI point is located in a received correlation function, and the distance between the point and the DLL, now affected by multipath, is measured. The difference between the ideal distance and the actual distance is the code tracking error resulting from multipath. The error is subtracted from the computed pseudorange or used to control the DLL. The method can be used to reduce the effects of all types of tracking error sources, such as signal transmission failure or code noise.
FILED Friday, December 01, 2000
APPL NO 09/728949
ART UNIT 2634 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/144
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 06867177 Pinsky
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) David J. Pinsky (Cresskill, New Jersey)
ABSTRACT The present invention provides a method of treating or preventing thrombotic or ischemic disorders in a subject which comprises administering an agent to the subject, wherein the agent inhibits ADP-mediated platelet aggregation by increasing ADP catabolism, and a method for determining whether a compound inhibits platelet aggregation by increasing ADP catabolism so as to treat or prevent thrombotic or ischemic disorders in a subject, comprising: (a) inducing thrombotic or ischemic disorders in an animal, which animal is an animal model for thrombotic or ischemic disorders; (b) measuring the stroke outcome in the animal, (c) measuring platelet deposition and/or fibrin deposition in ischemic tissue, and (d) comparing the stroke outcome in step (b) and the platelet deposition and/or fibrin deposition with that of the animal model in the absence of the compound so as to identify a compound capable of treating or preventing thrombotic or ischemic disorders in a subject.
FILED Friday, August 13, 1999
APPL NO 09/374586
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 06865926 O'Brien et al.
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) State of Oregon Acting by and through the State Board of Higher Education on behalf of Portland State University (Portland, Oregon)
INVENTOR(S) Robert J. O'Brien (Clackamas, Oregon);  Thomas R. Smith (Portland, Oregon)
ABSTRACT Methods and systems for analyzing samples, such as gas samples, are described. One method comprises providing a gas sample, increasing pressure applied to the gas sample to compress the sample to a smaller volume and provide a pneumatically focused gas sample, and analyzing the pneumatically focused gas sample using any of a variety of analytical techniques. Also disclosed are systems for gas analysis, including systems for analysis of pneumatically focused, and thereby concentrated, gas samples and for analysis of particulate matter in gas samples. Analytical systems constructed within personal computer cases also are disclosed.
FILED Wednesday, May 14, 2003
APPL NO 10/438517
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/23.270
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 15, 2005.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050315.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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