FedInvent™ Patents
Patent Details for Tuesday, March 29, 2005
This page was updated on Sunday, March 26, 2023 at 07:45 PM GMT
Department of Defense (DOD)
| US 06871565 | Allaei |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Quality Research, Development and Consulting, Inc. (Chaska, Minnesota) |
| INVENTOR(S) | Daryoush Allaei (Excelsior, Minnesota) |
| ABSTRACT | A method for controlling vibration energy in a structure having a vibrating member using a vibration confinement device is provided. The vibrating member has boundaries and vibrates relative to the boundaries. The method includes selecting a vibration confinement region in the vibrating member relative to the boundaries. Determining an effective torsional stiffness and an effective translational stiffness for the vibration confinement device is included in the method. The method includes determining an operating position relative to the boundaries for the vibration confinement device on the vibrating member to define a determined position. The method includes positioning the vibration confinement device at the determined position to substantially confine the vibration energy to the vibration confinement region. |
| FILED | Friday, October 17, 2003 |
| APPL NO | 10/688462 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Machine element or mechanism 074/574 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06871604 | Alexakis et al. |
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| ASSIGNEE(S) | Pyrogenesis, Inc. (Montreal, Canada); The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Theodora Alexakis (Montreal, Canada); Jon Williams Cofield (Washington, Maryland); Platon Manoliadis (Montreal, Canada); Eugene Ellis Nolting (Columbia, Maryland); Peter George Tsantrizos (Montreal, Canada); Roy V. Richard (Natick, Massachusetts) |
| ABSTRACT | Solid combustible waste materials are converted into highly efficient fuel by subjecting such materials to size reduction in suitable size-reducing equipment. The last piece of the equipment is a mill which pulverizes the waste materials into fine particles having a high surface to mass ratio and forming a highly efficient fuel when these particles are directly injected into a combustion reactor operating at high temperature. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/259547 |
| ART UNIT | 3749 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Furnaces 110/342 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06871610 | Galliano |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Carlos E. Galliano (North Kingstown, Rhode Island) |
| ABSTRACT | An assembly for launching bodies from an underwater platform having a pressure hull, and an outer hull subject to free flooding. The assembly includes a module having a proximal end outboard of the pressure hull portion of the platform, a distal end disposed proximate and in alignment with a launch opening in the outer hull portion, and a chamber in the module extending from the distal end of the module to proximate the proximal end of the module, the module chamber being adapted to receive and retain one of the bodies. Support structure on the platform retains the module. A pump on the platform is in communication with water outside the pressure hull, and an impulse tank on the platform is in communication with the pump. A manifold is in communication with the impulse tank for directing outflow of water from the impulse tank to the chamber to eject the body from the chamber. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/456163 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/238 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06871645 | Wartman et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard Wartman (Pensacola, Florida); Michael Stiney (Pensacola, Florida); Eric Bower (Pensacola, Florida); Paul Gardetto (Yorktown, Virginia); Charles Vacchiano (Gulf Breeze, Florida); Kenneth Sausen (Arlington, Tennessee) |
| ABSTRACT | The present invention includes a non-rebreathing circuit coupled with computer-controlled gas adjustments. Ambient air is diluted with nitrogen on a breath-by-breath basis to provide precise control over the inspired concentration of oxygen/nitrogen mixture, thereby simulating selected altitudes on an almost instantaneous basis. Carbon dioxide and water vapor exhaled by the subject are released into the environment and absorption is not necessary. In addition, the mixed gas can be administered through a standard aviator's oxygen mask, increasing the realism of the simulation and removing obvious external cues on the nature of the experiment. Maintenance on the mixing loop is low when compared to re-breathing units, since no consumable items are necessary to absorb water vapor or carbon dioxide. A mixing device provides a homogenized mixture of nitrogen/oxygen fluid to the subject. |
| FILED | Monday, September 16, 2002 |
| APPL NO | 10/244003 |
| ART UNIT | 3743 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery 128/203.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06871797 | Peters |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Donald W. Peters (Colchester, Connecticut) |
| ABSTRACT | A convergent/divergent nozzle for a gas turbine engine has a throat portion of non-constant radius of curvature varying from an upstream high value to an intermediate low value and then to a downstream high value. |
| FILED | Monday, July 07, 2003 |
| APPL NO | 10/614632 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/265.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872266 | Ciaramitaro |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David Ciaramitaro (Ridgecrest, California) |
| ABSTRACT | A recyclable energetic composition and method of processing energetic compositions cured by cyclo-addition of azido groups of the polymer binder with di- and/or tri-acetylene curatives (components) to form triazole linkages, such that the cure reaction is accelerated or delayed at will without degradation, allowing storage and later recycling of unused material for reduction of hazardous waste, and reduction of pollution. |
| FILED | Thursday, October 30, 2003 |
| APPL NO | 10/699479 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive and thermic compositions or charges 149/109.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872398 | Castric et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Peter Castric (Pittsburgh, Pennsylvania); Alan S. Cross (Chevy Chase, Maryland); Jerald C. Sadoff (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to a broadly reactive vaccine against Gram-negative bacteria which is composed of a biological glycan-pilus conjugate. The conjugate core is a common pilus type to which is attached the glycan of choice in vivo. Pooling of these bioconjugates produces a multivalent vaccine. These pili give high bronchial titers when delivered by the intranasal route. Mice vaccinated with pure glycosylated P. aeruginosa strain 1244 pili in this manner are protected against respiratory challenge with P. aeruginosa strain 1244. The present invention further relates to a DNA and amino acid sequence of a new gene, pilO, which is capable of glycosylating pilin of Gram-negative bacteria and uses thereof. |
| FILED | Wednesday, June 23, 1999 |
| APPL NO | 09/337393 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/242.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872439 | Fearing et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ronald S. Fearing (El Cerrito, California); Metin Sitti (Pittsburgh, Pennsylvania) |
| ABSTRACT | A fabricated microstructure comprising at least one protrusion capable of providing an adhesive force at a surface of between about 60 and 2,000 nano-Newtons. A stalk supports the protrusion at an oblique angle relative to a supporting surface. The microstructure can adhere to different surfaces. |
| FILED | Wednesday, July 17, 2002 |
| APPL NO | 10/197763 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872471 | Epstein et al. |
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| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Arthur J. Epstein (Bexley, Ohio); Qianbing Zheng (Powell, Ohio); Run G. Sun (Columbus, Ohio) |
| ABSTRACT | The present invention includes infrared emitting materials and infrared emitting devices. The present invention demonstrates 1.54 micron infrared PL and EL emission from an organic complex. This provides a very simple way to obtain a light source at 1.54 micron wavelength that may be both optically and electrically pumped. |
| FILED | Monday, March 05, 2001 |
| APPL NO | 09/799171 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872504 | Fedynyshyn |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Theodore H. Fedynyshyn (Sudbury, Massachusetts) |
| ABSTRACT | The present invention provides methods for lithography utilizing X-ray radiation. More particularly, the methods of the invention can be employed for lithography at wavelengths in a range between about 0.8 nm and 30 nm, and more particularly, at wavelengths in a range between 0.8 and 1.2 nm. The methods of the invention employ photoresist compositions having fluorinated polymers with a fluorine content of at least about 10% by weight to provide enhanced sensitivity for X-ray lithography. |
| FILED | Tuesday, December 10, 2002 |
| APPL NO | 10/315356 |
| ART UNIT | 1752 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872929 | Neculaes et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Vasile B. Neculaes (Ann Arbor, Michigan); Ronald M. Gilgenbach (Ann Arbor, Michigan); Yue-Ying Lau (Potomac, Maryland) |
| ABSTRACT | Low-noise, crossed-field devices such as a microwave magnetron, a microwave oven utilizing same, crossed-field amplifier and a method of converting a noisy magnetron to a low-noise magnetron utilize an azimuthally varying, axial magnetic field. The magnetic configuration reduces and eliminates microwave and radio frequency noise. This microwave noise is present near the carrier frequency and as sidebands, far separated from the carrier. The device utilizes azimuthally varying, axial, magnetic field perturbations. In one embodiment, at least one permanent magnet is placed against the azimuthally-symmetric, axial magnetic field magnetron magnets (four magnets work especially well). This additional permanent magnet(s) causes the axial magnetic field to vary azimuthally in the magnetron and completely eliminates the microwave noise and unwanted frequencies. |
| FILED | Thursday, April 17, 2003 |
| APPL NO | 10/417655 |
| ART UNIT | 3742 — Organic Chemistry |
| CURRENT CPC | Electric heating 219/761 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872971 | Hutchinson et al. |
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| ASSIGNEE(S) | The State of Oregon acting by and through the State Board of Higher Education on behalf of The University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | James E. Hutchinson (Eugene, Oregon); Scott M. Reed (Eugene, Oregon); Martin N. Wybourne (Hanover, New Hampshire) |
| ABSTRACT | A method for forming arrays of metal, alloy, semiconductor or magnetic clusters is described. The method comprises placing a scaffold on a substrate, the scaffold comprising, for example, polynucleotides and/or polypeptides, and coupling the clusters to the scaffold. Methods of producing arrays in predetermined patterns and electronic devices that incorporate such patterned arrays are also described. |
| FILED | Thursday, February 19, 2004 |
| APPL NO | 10/783515 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872983 | Liu |
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| ASSIGNEE(S) | Finisar Corporation (Sunnyvale, California) |
| INVENTOR(S) | Yue Liu (Plymouth, Minnesota) |
| ABSTRACT | The invention includes an opto-electronic device with a device region having a bottom surface and a top surface, and a top emitting/illumination window, an isolation region, wherein the isolation region electrically isolates the device region, a superstrate having a bottom surface and a top surface, wherein the bottom surface is positioned upon the top surface of the device region, a micro-optical device positioned upon the top surface of the superstrate. The invention also includes a method of fabricating an opto-electronic device having the steps of forming a device region with a top surface and a bottom surface upon a substrate, forming an isolation region, wherein the isolation region surrounds the device region, forming a superstrate upon the top surface of the device region, integrating a micro-optical device on the top surface of the device region, and bonding an integrated circuit to the bottom surface of the device region. |
| FILED | Monday, November 11, 2002 |
| APPL NO | 10/292578 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872991 | Ngo et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Hung C. Ngo (Austin, Texas); Jente B. Kuang (Austin, Texas); Kevin J. Nowka (Round Rock, Texas) |
| ABSTRACT | Circuits within a logic domain use partitioned power supply buses. Selected of the power supply buses are coupled to the power supply voltage potentials with electronic switches with gradated conductivity and leakage current. When the circuits are actively switching during a logic operation, the power supply voltage potentials are coupled to the buses with maximum conductivity. At predetermined times later, selected of the electronic switches are switched OFF to reduce leakage current. Lower conductivity and thus lower leakage switches remain ON to ensure corresponding logic states are maintained during a controlled low leakage time period. Various logic configurations are used to switch OFF high leakage devices. |
| FILED | Thursday, May 06, 2004 |
| APPL NO | 10/840708 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872993 | Zhu et al. |
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| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Theodore Zhu (Maple Grove, Minnesota); Jeffrey S. Sather (Medina, Minnesota) |
| ABSTRACT | A monolithically formed ferromagnetic thin-film memory is disclosed that has local shielding on at least two sides of selected magnetic storage elements. The local shielding preferably extends along the back and side surfaces of a word line and/or digital lines of a conventional magnetic memory. In this configuration, the local shielding not only may help reduce externally generated EMI, internally generated cross-talk and other unwanted fields in the magnetic bit region, but may also help enhance the desired magnetic fields in the bit region. |
| FILED | Tuesday, May 25, 1999 |
| APPL NO | 09/318073 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/259 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873078 | Piec et al. |
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| ASSIGNEE(S) | General Atomics (San Diego, California) |
| INVENTOR(S) | Zbigniew S. Piec (San Diego, California); Alan Robert Langhorn (San Diego, California); David A. Hazlebeck (San Diego, California) |
| ABSTRACT | A homopolar machine which exhibits reduced wear and prolonged brush life. Current collectors or brushes are mounted so as to maintain substantially constant contact pressure and so that all of them are polarized negative. Brush holders are provided which facilitate the application of precise and constant contact pressure in a region of very high magnetic forces. |
| FILED | Friday, October 10, 2003 |
| APPL NO | 10/684090 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/178 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873237 | Chandrasekaran et al. |
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| ASSIGNEE(S) | Innovative Technology Licensing, LLC (Thousand Oaks, California) |
| INVENTOR(S) | Sriram Chandrasekaran (Burbank, California); Vivek Mehrotra (Newbury Park, California); Jian Sun (Cedar Rapids, Iowa) |
| ABSTRACT | There is disclosed a core structure with a very low profile, high power density and lower losses. Higher core surface area and improved core utilization in terms of flux density are other desirable feature in the disclosed design. The disclosed design also allowed for a larger core area where the DC fluxes are added, thereby reducing the air-gap requirements in the cores derived from low saturation density materials such as ferrites. The cellular nature of the design can also be effectively employed in vertically packaged power converters and modules. |
| FILED | Thursday, April 18, 2002 |
| APPL NO | 10/126477 |
| ART UNIT | 2832 — Printing/Measuring and Testing |
| CURRENT CPC | Inductor devices 336/83 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873467 | Tejada et al. |
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| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | John Anthony Tejada (Garland, Texas); Erwin E. Cooper (Valley View, Texas); John Paul Schaefer (Plano, Texas) |
| ABSTRACT | A method for providing optical alignment for a visible wavelength reflective system is provided. The method includes positioning a first mirror blank on a lathe fixture. The first mirror blank comprises a single precision pinhole. The first mirror blank is secured to the lathe fixture. A first mirror is generated from the first mirror blank. |
| FILED | Friday, August 24, 2001 |
| APPL NO | 09/939384 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/627 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873572 | Frank |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas A. Frank (Middletown, Rhode Island) |
| ABSTRACT | A multi-port projector of acoustic energy in water includes a cylindrical hollow transducer having open annular ends. A thin, flexible member is secured to each annular end to extend across each opening to be displaced by the transducer, and the transducer and flexible members form an interior sealed from ambient water. A battery/electronics module is in the interior and is spaced from the transducer and flexible members to couple driving signals to the transducer for reciprocally displacing it and the flexible members in response to the driving signals. An inert liquid fills the interior around the module, and an open truss on each annular end exposes the flexible members to the ambient water. Cylindrical portions coaxially extending with the transducer on a common longitudinal axis are connected to the open trusses for projecting acoustic energy of lower frequency than conventional cylindrical transducers of similar size. |
| FILED | Monday, May 03, 2004 |
| APPL NO | 10/839449 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/174 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873886 | Mullen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Mullen (Bedford, Indiana); Keith D. Milhouse (Bloomington, Indiana); Paul L. Schmidt (Bloomfield, Indiana) |
| ABSTRACT | The present application discloses an open system architecture and software system for plug and play modular mission payloads in aerial vehicles. The improved software moves the control function of mission payloads away from the ground station and into the aerial vehicle. The plug & play web-based payload interface software resides in a payload interface controller in the vehicle, and this is networked via a uniform resource locator (URL) address to a ground control station. Consequently, when new payloads are added to the system, integration issues and costs are minimized. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/307534 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873887 | Zagranski et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Goodrich Pump and Engine Control Systems, Inc. (West Hartford, Connecticut) |
| INVENTOR(S) | Raymond D. Zagranski (Somers, Connecticut); Robert D. Niebanck (Milford, Connecticut) |
| ABSTRACT | A system for performing feed-forward anticipation of rotor torque demand on a helicopter engine is disclosed which includes a flight control computer adapted and configured to predict the total torque required at the main and tail rotors of the helicopter, and an engine fuel control system adapted and configured to compute the rate of change of the total torque, convert the rate of change of the total torque to an engine acceleration/deceleration rate, and obtain a demanded engine acceleration/deceleration rate therefrom. |
| FILED | Tuesday, November 12, 2002 |
| APPL NO | 10/292045 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873893 | Sanghera et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jasbinder Sanghera (Ashburn, Virginia); Lynda Busse (Alexandria, Virginia); Ishwar Aggarwal (Fairfax Station, Virginia) |
| ABSTRACT | This invention pertains to a jam head and to a protection system. The jam head is rotatable around at least two separate axes and includes a first part rotatable around a first axis and a second part rotatably connected to the first part and rotatable around a second axis; a viewing port in the first part for viewing an object; at least one reflecting surface for conveying an image through the port; a camera optically connected via the at least one reflecting surface to the port; and a unitary infrared transmitting glass fiber of constant core diameter passing from the laser to and through the first and the second parts for conveying an energetic infrared optical signal and an exit port through which the optical signal passes. The protection system is mounted on a movable platform and includes a detector for locating a threat; an electronic and control system connected to the detector for receiving a signal from the detector; a laser connected to the electronic and control system; and the jam head. |
| FILED | Friday, August 01, 2003 |
| APPL NO | 10/632211 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873945 | Ross et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan R. Ross (Waldorf, Maryland); Conan R. Schultz (New Carrollton, Maryland); Michael K Oetjen (Alexandria, Virginia) |
| ABSTRACT | The present invention comprises a device which is inert and “thermally-equivalent” to actual ordnance. The device can travel with live ordnance and track the propellant temperatures in order to get a more precise propellant temperature for the ordnance. The device comprises a thermally equivalent inert grain instrumented with thermocouples, connected to a data recorder, and packaged in scaled-down ordnance hardware. The hardware is scaled down to enable the device to more easily travel with live munitions. |
| FILED | Monday, December 18, 2000 |
| APPL NO | 09/853076 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873946 | Robinson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David F. Robinson (Fredericksburg, Virginia) |
| ABSTRACT | A method for presenting a graphic user interface (GUI) facilitating generation of selected ones of a Euler grid and a Navier-Stokes grid from a single set of predetermined parameters includes step for defining the geometry of a vehicle to be tested, defining the environment in which the vehicle is to tested, generating the selected ones of the Euler grid and the Navier-Stokes grid responsive the set of predetermined parameters generated in two defining steps, and post-processing the output of the generating step. Computer readable instructions for permitting a general purpose computer to instantiate a graphic user interface (GUI) generating selected ones of a Euler grid and a Navier-Stokes grid from a single set of predetermined parameters and a storage medium storing the computer readable instructions are also described. |
| FILED | Wednesday, December 01, 1999 |
| APPL NO | 09/451718 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873961 | Thorpe et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven W. Thorpe (North Kingstown, Rhode Island); Robert C. Higgins (Tiverton, Rhode Island) |
| ABSTRACT | A method and apparatus for computer-assisted project analysis. Planned values for successive times for each of a plurality of parameters are stored in a database. Another database receives measured values of the parameters at the successive times. A statistical analysis including comparison, correlation and differentiation functions generate a set of output functions that then are displayed to assist in the analysis of the project. |
| FILED | Wednesday, September 09, 1998 |
| APPL NO | 09/152471 |
| ART UNIT | 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06874108 | Abramovici et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Agere Systems Inc. (Allentown, Pennsylvania); University of North Carolina at Charlotte (Charlotte, North Carolina) |
| INVENTOR(S) | Miron Abramovici (Berkeley Heights, New Jersey); John M. Emmert (Dayton, Ohio); Charles E. Stroud (Charlotte, North Carolina) |
| ABSTRACT | A method of fault tolerant operation of an adaptive computing system includes identifying a faulty resource in a signal path of the adaptive computing system, reconfiguring the signal path to avoid the faulty resource, estimating a time delay created by reconfiguring the signal path, and adjusting a system clock period to accommodate the time delay. In a preferred embodiment, an FPGA is configured into an initial self-testing area and a working area. Resources located within the self-testing area are tested and faulty resources identified. The FPGA is then reconfigured to avoid the identified faulty resources. When the resources are reconfigured for fault tolerant operation, signal path delays may be introduced into the system. If the signal path delays are in a critical path, a period of a system clock may be adjusted in order to insure proper fault tolerant operation. |
| FILED | Tuesday, August 27, 2002 |
| APPL NO | 10/228444 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/725 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 06872385 | Fidler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Isaiah J. Fidler (Houston, Texas); Zhongyun Dong (Sugar Land, Texas); Weixin Lu (Houston, Texas) |
| ABSTRACT | Disclosed are methods and compositions useful in the recruitment, activation and initiation of proliferation of immune cells. The instant invention relates to the discovery that specific insect cells and insect cell compositions exhibit adjuvant properties. The added benefit of this system is that the insect cells utilized may be transformed with an expression system and thus proteins may be introduced into the composition through direct protein expression by the cells. The claimed compositions and methods are particularly relevant in anti-tumor and cancer therapy. Of specific interest is the ability of the compositions of the invention to elicit a response that controls not only the primary tumor but also any metastatic cells or metastatic tumors which subsequently arise. |
| FILED | Thursday, May 31, 2001 |
| APPL NO | 09/872162 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/85.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872391 | Spiegelman et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dana-Farber Cancer Institute (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Pere Puigserver (Brookline, Massachusetts); Zhidan Wu (Boston, Massachusetts); Guillaume Adelmant (Boston, Massachusetts) |
| ABSTRACT | The invention provides isolated nucleic acids molecules, designated PGC-1 nucleic acid molecules, which encode proteins which can modulate various adipocyte-associated activities including, for example, thermogenesis in adipocytes, e.g., brown adipocytes, and adipogenesis. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1 gene has been introduced or disrupted. The invention still further provides isolated PGC-1 proteins, fusion proteins, antigenic peptides and anti-PGC-1 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/256889 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872394 | Bohach |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Idaho Research Foundation, Inc. (Moscow, Idaho) |
| INVENTOR(S) | Gregory I. Bohach (Moscow, Idaho) |
| ABSTRACT | Pyrogenic toxins, such as staphylococcal enterotoxins, modified in the disulfide loop region are provided. The modified toxins retain useful biological properties but have substantially reduced toxicity compared to the corresponding unmodified native toxin. The native pyrogenic toxins are typically modified by deletions within the disulfide loop region to produce modified enterotoxins having 100-fold or greater decrease in toxicity. |
| FILED | Tuesday, December 01, 1998 |
| APPL NO | 09/555115 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872395 | Kawaoka |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Madison, Wisconsin) |
| ABSTRACT | A method to prepare viruses lacking ion channel activity is provided. |
| FILED | Thursday, April 12, 2001 |
| APPL NO | 09/834095 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/206.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872406 | Qi |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Children's Hospital Research Foundation (Cincinnati, Ohio) |
| INVENTOR(S) | Xiaoyang Qi (Cincinnati, Ohio) |
| ABSTRACT | The present invention comprises a method for delivering pharmaceutical agents within and/or through the dermal and mucosal membranes, utilizing a fusogenic protein. The fusogenic protein is associated with a phospholipid membrane, such as a liposome. The liposome contains the pharmaceutical agent. Preferred fusogenic proteins include saposin C and other proteins, polypeptides and peptide analogs derived from saposin C. The active agent contained within the liposome may comprise large biomolecules and/or small organic molecules. This technology can be used for both cosmetic and medicinal applications in which the objective is delivery of the active agent within and/or beneath the biological membrane. |
| FILED | Friday, February 09, 2001 |
| APPL NO | 09/780438 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872518 | Zauderer |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Maurice Zauderer (Pittsford, New York) |
| ABSTRACT | The present invention relates to methods for the identification of antigens recognized by cytotoxic T cells (CTLs) and specific for human tumors, cancers, and infected cells, and the use of such antigens in immunogenic compositions or vaccines to induce regression of tumors, cancers, or infections in mammals, including humans. The invention encompasses methods for induction and isolation of cytotoxic T cells specific for human tumors, cancers and infected cells, and for improved selection of genes that encode the target antigens recognized by these specific T cells. The invention also relates to differential display methods that improve resolution of, and that reduce the frequency of false positives of DNA fragments that are differentially expressed in tumorous, cancerous, or infected tissues versus normal tissues. The invention further relates to the engineering of recombinant viruses as expression vectors for tumor, cancer, or infected cell-specific antigens. |
| FILED | Monday, September 22, 1997 |
| APPL NO | 08/935377 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872519 | Sokoloff et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mirus Bio Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Alexander V. Sokoloff (Madison, Wisconsin); Jon A. Wolff (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to compositions and methods for the selection and use of surface exposed epitopes. The present invention includes in vivo and in vitro phage peptide diplay methods for the identification and selection of peptides and peptide associated factors with desired properties (e.g., targeting specificity, stability, etc.). The present invention further provides methods and compositions for the isolation and identification of peptide-specific antibodies. The present invention also includes methods and compositions employing nuclear localization signals for enhanced nuclear transport and expression of DNA. |
| FILED | Thursday, April 27, 2000 |
| APPL NO | 09/559021 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872533 | Toland et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amanda E. Toland (Greenbrae, California); Allan Balmain (Tiburon, California) |
| ABSTRACT | The present invention provides methods for determining cancer susceptibility in a human subject by identifying in a nucleic acid sample from the subject, a nucleotide occurrence of a single nucleotide polymorphism (SNP) of the STK15 gene, including the STK15 Ile31 polymorphism. The invention provides isolated polynucleotides, polypeptides, specific binding pair members, and cells useful for identifying agents that affect tumor susceptibility. Furthermore, the invention provides methods for detecting low penetrance tumor susceptibility genes. |
| FILED | Monday, July 29, 2002 |
| APPL NO | 10/209324 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872542 | Hultgren et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SIGA Pharmaceuticals, Inc. (New York, New York); Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Scott Hultgren (Ballwin, Missouri); Meta Kuehn (Berkeley, California); Zheng Xu (Blue Bell, Pennsylvania); Derek Ogg (Uppsala, Sweden); Mark Harris (Uppsala, Sweden); Matti Lepisto (Lund, Sweden); Charles Hal Jones (Saint Louis, Missouri); Jan Kihlberg (Dalby, Sweden) |
| ABSTRACT | Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed. |
| FILED | Wednesday, March 07, 2001 |
| APPL NO | 09/799584 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872546 | Hastings et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Human Genome Sciences, Inc. (Rockville, Maryland); The American Red Cross (Falls Church, Virginia) |
| INVENTOR(S) | Gregg A. Hastings (Westlake Village, California); Gene Liau (Darnestown, Maryland); Elena Tsifrina (Owings Mills, Maryland) |
| ABSTRACT | The present invention relates to full-length WF-HABP, WF-HABP, OE-HABP, and BM-HABP, novel members of the hyaluronan receptor family. The invention provides isolated nucleic acid molecules encoding human to full-length WF-HABP, WF-HABP, OE-HABP, and BM-HABP receptors. Full-length WF-HABP, WF-HABP, OE-HABP, and BM-HABP polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of full-length WF-HABP, WF-HABP, OE-HABP, and BM-HABP receptor activity. Also provided are diagnostic methods for detecting disease states related to the aberrant expression of full-length WF-HABP, WF-HABP, OE-HABP, and BM-HABP receptors. Further provided are therapeutic methods for treating disease states including, but not limited to, proliferative conditions, metastasis, inflammation, ischemia, host defense dysfunction, immune surveillance dysfunction, arthritis, multiple sclerosis, autoimmunity, immune dysfunction, and allergy. |
| FILED | Monday, December 20, 1999 |
| APPL NO | 09/466778 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872559 | Welch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Rodney A. Welch (Madison, Wisconsin); Wyndham W. Lathem (Madison, Wisconsin) |
| ABSTRACT | Disclosed is a pO157 plasmid-specified polypeptide found in E. coli EDL933and other enterohemorrhagic E. coli that binds to and cleaves C1-esterase inhibitor. Also disclosed are methods employing the polypeptide for diagnosing and treating colitis or hemolytic uremic syndrome, and methods of detecting potential therapeutics. |
| FILED | Friday, October 26, 2001 |
| APPL NO | 10/002309 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/212 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872563 | Beckwith et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Board of Regents, University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jonathan Beckwith (Cambridge, Massachusetts); Fredrik Aslund (Stockholm, Sweden); Paul H. Bessette (Camarillo, California); George Georgiou (Austin, Texas); Daniel Ritz (Everett, Massachusetts); Jackie Eun-ah Lim (Shrewsbury, Massachusetts) |
| ABSTRACT | The invention provides composition and methods for producing proteins of interest which comprise at least one disulfide bond, include proteins which in their mature form do not contain disulfide bonds, but whose precursor molecule contained at least one disulfide bond. The methods employ a host cell modified to more efficiently produce properly folded disulfide bond containing proteins. The host cells generally contain a mutation in one or more reductase genes, and can be further genetically modified to increase their growth rate, and are further optionally modified to increase the expression of a catalyst of disulfide bond formation. Host cells, methods for using such to produce proteins of interest, proteins of interest produced by these methods are within the scope of the invention. |
| FILED | Thursday, October 05, 2000 |
| APPL NO | 09/679705 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872574 | Cravatt et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Benjamin F. Cravatt (La Jolla, California); Erik Sorensen (San Diego, California); Matthew P. Patricelli (San Diego, California); Martha Lovato (San Diego, California); Gregory Adam (San Diego, California) |
| ABSTRACT | The present invention provides methods for analyzing proteomes, as cells or lysates. The analysis is based on the use of probes that have specificity to the active form of proteins, particularly enzymes and receptors. The probes can be identified in different ways. In accordance with the present invention, a method is provided for generating and screening compound libraries that are used for the identification of lead molecules, and for the parallel identification of their biological targets. By appending specific functionalities and/or groups to one or more binding moieties, the reactive functionalities gain binding affinity and specificity for particular proteins and classes of proteins. Such libraries of candidate compounds, referred to herein as activity-based probes, or ABPs, are used to screen for one or more desired biological activities or target proteins. |
| FILED | Monday, April 16, 2001 |
| APPL NO | 09/836148 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/119 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872575 | Regnier |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Fred B. Regnier (West Lafayette, Indiana) |
| ABSTRACT | A method for protein identification in complex mixtures that utilizes affinity selection of constituent proteolytic peptide fragments unique to a protein analyte. These “signature peptides” function as analytical surrogates. Mass spectrometric analysis of the proteolyzed mixture permits identification of a protein in a complex sample without purifying the protein or obtaining its composite peptide signature. |
| FILED | Monday, September 16, 2002 |
| APPL NO | 10/244784 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/174 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872715 | Santi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Kosan Biosciences, Inc. (Hayward, California) |
| INVENTOR(S) | Daniel Santi (San Francisco, California); David C. Myles (Kensington, California); Zong-Qiang Tian (Fremont, California); C. Richard Hutchinson (San Mateo, California); Robert Johnson (Lafayette, California); Yi-Qing Zhou (Lafayette, California); Li Feng (Fremont, California) |
| ABSTRACT | The invention relates to benzoquinone ansamycin analogs useful for the treatment of cancer and other diseases or conditions characterized by undesired cellular proliferation or hyperproliferation. Therapies involving the administration of such benzoquinone ansamycin analogs, optionally in combination with an inhibitor of an HSP90 client protein, are useful to treat cancer and non-cancerous disease conditions. |
| FILED | Monday, August 05, 2002 |
| APPL NO | 10/212962 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872728 | Zhu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Neurocrine Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Yun-Fei Zhu (San Diego, California); Chen Chen (San Diego, California); Fabio C. Tucci (San Diego, California); Zhiqiang Guo (San Diego, California); Timothy D. Gross (San Diego, California); Martin Rowbottom (La Jolla, California); R. Scott Struthers (Encinitas, California) |
| ABSTRACT | GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, Q, R1, R2, R3a, R3b, R4, R5, R6 and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof. |
| FILED | Thursday, February 06, 2003 |
| APPL NO | 10/361144 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/269 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872816 | Hall et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Third Wave Technologies, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Jeff G. Hall (Madison, Wisconsin); Victor I. Lyamichev (Madison, Wisconsin); Andrea L. Mast (Madison, Wisconsin); Mary Ann D. Brow (Madison, Wisconsin); Robert W. Kwiatkowski (Verona, Wisconsin); Stephanie H. Vavra (Waunakee, Wisconsin) |
| ABSTRACT | The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample. |
| FILED | Tuesday, March 24, 1998 |
| APPL NO | 09/381212 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872841 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Kuo-Hsiung Lee (Chapel Hill, North Carolina); Zhiyan Xiao (Chapel Hill, North Carolina); Kenneth F. Bastow (Chapel Hill, North Carolina) |
| ABSTRACT | Etoposide analogs such as 4′-O-demethyl-4β-[4″-(methyl-L-tyrosine-N-carbonyl)-anilino]-4-desoxy-podophyllotoxin (12) and 4′-O-demethyl-4β-[4″-(methyl-L-tryptophan-N-carbonyl)-anilino]-4-desoxypodophyllotoxin (13) are described, along with pharmaceutical formulations containing the same, methods of use thereof, and intermediates and methods of making the same. |
| FILED | Wednesday, January 22, 2003 |
| APPL NO | 10/349351 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/432 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872842 | Holton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Florida State University (Tallahassee, Florida) |
| INVENTOR(S) | Robert A. Holton (Tallahassee, Florida); Ki-byung Chai (Junnam, South Korea); Hossain Nadizadeh (Little Falls, New Jersey) |
| ABSTRACT | Taxane derivatives having a 3′ butenyl substituted C13 side chain. |
| FILED | Friday, March 29, 2002 |
| APPL NO | 10/113427 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/510 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873872 | Gluckman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | George Mason University (Fairfax, Virginia) |
| INVENTOR(S) | Bruce J. Gluckman (Arlington, Virginia); Steven J. Schiff (Bethesda, Maryland) |
| ABSTRACT | The present invention relates to devices and methods of modifying the neuronal activity of a neural system comprising neurons, comprising, one or more of the following steps, measuring the neuronal activity of a neural system; and applying an oriented electric field to said neural system effective to modify the neuronal activity of the neural system, wherein the magnitude and polarity of said applied electric field is changed in response to the measured neuronal activity. The present invention also relates to devices and methods for treating brain disorders, such as epilepsy and Parkinson's disease, comprising, one or more of the following steps, applying a sub-threshold and oriented electric field in situ to the brain of a patient having such a disorder in an amount effective to reduce the abnormal activity of the brain, wherein the electric field is applied through field electrodes in contact with the brain. The present invention also relates to methods and devices for restoring or repairing a brain function, such as sensation (e.g., taste, or smell), somatic activity, auditory activity, visual activity, or motor activity. It can also be used for testing drugs, pharmacological agents, and other modulators of neuronal function. |
| FILED | Friday, October 11, 2002 |
| APPL NO | 10/268917 |
| ART UNIT | 3742 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06871556 | Andresen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brian D. Andresen (Livermore, California); Erik Randich (Manteca, California) |
| ABSTRACT | A porous protective sheath for active extraction media used in solid phase microextraction (SPME). The sheath permits exposure of the media to the environment without the necessity of extending a fragile coated fiber from a protective tube or needle. Subsequently, the sheath can pierce and seal with GC-MS septums, allowing direct injection of samples into inlet ports of analytical equipment. Use of the porous protective sheath, within which the active extraction media is contained, mitigates the problems of: 1) fiber breakage while the fiber is extended during sampling, 2) active media coating loss caused by physical contact of the bare fiber with the sampling environment; and 3) coating slough-off during fiber extension and retraction operations caused by rubbing action between the fiber and protective needle or tube. |
| FILED | Friday, July 27, 2001 |
| APPL NO | 09/917475 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/863.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872378 | Weimer et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Midwest Research Institute (Kansas City, Missouri) |
| INVENTOR(S) | Alan W. Weimer (Niwot, Colorado); Jaimee K. Dahl (Superior, Colorado); J. Roland Pitts (Lakewood, Colorado); Allan A. Lewandowski (Evergreen, Colorado); Carl Bingham (Lakewood, Colorado); Joseph R. Tamburini (San Jose, California) |
| ABSTRACT | The present invention provides an environmentally beneficial process using concentrated sunlight to heat radiation absorbing particles to carry out highly endothermic gas phase chemical reactions ultimately resulting in the production of hydrogen or hydrogen synthesis gases. |
| FILED | Tuesday, May 08, 2001 |
| APPL NO | 10/239706 |
| ART UNIT | 1754 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Chemistry of inorganic compounds 423/650 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872433 | Seward et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kirk P. Seward (Pleasanton, California); Peter A. Krulevitch (Pleasanton, California) |
| ABSTRACT | Micro-electromechanical tools for minimally invasive techniques including microsurgery. These tools utilize composite shape memory alloy (SMA), shape memory polymer (SMP) and combinations of SMA and SMP to produce catheter distal tips, actuators, etc., which are bistable. Applications for these structures include: 1) a method for reversible fine positioning of a catheter tip, 2) a method for reversible fine positioning of tools or therapeutic catheters by a guide catheter, 3) a method for bending articulation through the body's vasculature, 4) methods for controlled stent delivery, deployment, and repositioning, and 5) catheters with variable modulus, with vibration mode, with inchworm capability, and with articulated tips. These actuators and catheter tips are bistable and are opportune for in vivo usage because the materials are biocompatible and convenient for intravascular use as well as other minimal by invasive techniques. |
| FILED | Tuesday, March 27, 2001 |
| APPL NO | 09/819111 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/36.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872455 | Sadigh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Babak Sadigh (Oakland, California); Thomas J. Lenosky (Pleasanton, California); Tomas Diaz de la Rubia (Danville, California); Martin Giles (Hillsborough, Oregon); Maria-Jose Caturla (Livermore, California); Vidvuds Ozolins (Pleasanton, California); Mark Asta (Evanston, Illinois); Silva Theiss (St. Paul, Minnesota); Majeed Foad (Santa Clara, California); Andrew Quong (Livermore, California) |
| ABSTRACT | A method for enhancing the equilibrium solubility of boron ad indium in silicon. The method involves first-principles quantum mechanical calculations to determine the temperature dependence of the equilibrium solubility of two important p-type dopants in silicon, namely boron and indium, under various strain conditions. The equilibrium thermodynamic solubility of size-mismatched impurities, such as boron and indium in silicon, can be raised significantly if the silicon substrate is strained appropriately. For example, for boron, a 1% compressive strain raises the equilibrium solubility by 100% at 1100° C.; and for indium, a 1% tensile strain at 1100° C., corresponds to an enhancement of the solubility by 200%. |
| FILED | Wednesday, July 23, 2003 |
| APPL NO | 10/626132 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/446 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872816 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Third Wave Technologies, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Jeff G. Hall (Madison, Wisconsin); Victor I. Lyamichev (Madison, Wisconsin); Andrea L. Mast (Madison, Wisconsin); Mary Ann D. Brow (Madison, Wisconsin); Robert W. Kwiatkowski (Verona, Wisconsin); Stephanie H. Vavra (Waunakee, Wisconsin) |
| ABSTRACT | The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample. |
| FILED | Tuesday, March 24, 1998 |
| APPL NO | 09/381212 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872817 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the Univ. of California (Oakland, California) |
| INVENTOR(S) | Joe W. Gray (Livermore, California); Daniel Pinkel (Walnut Creek, California) |
| ABSTRACT | Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogeneous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes. |
| FILED | Monday, June 05, 1995 |
| APPL NO | 08/463830 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/25.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872988 | Goyal |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit Goyal (Knoxville, Tennessee) |
| ABSTRACT | A laminate semiconductor article includes a flexible substrate, an optional biaxially textured oxide buffer system on the flexible substrate, a biaxially textured Ir-based buffer layer on the substrate or the buffer system, and an epitaxial layer of a semiconductor. Ir can serve as a substrate with an epitaxial layer of a semiconductor thereon. |
| FILED | Tuesday, March 23, 2004 |
| APPL NO | 10/808815 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/190 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873241 | Sanchez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert O. Sanchez (Los Lunas, New Mexico); Shelton Gunewardena (Walnut, California); James V. Masi (Cape Elizabeth, Maine) |
| ABSTRACT | An electrical component in the form of an inductor or transformer is disclosed which includes one or more coils and a magnetic polymer material located near the coils or supporting the coils to provide an electromagnetic interaction therewith. The magnetic polymer material is preferably a cured magnetic epoxy which includes a mercaptan derivative having a ferromagnetic atom chemically bonded therein. The ferromagnetic atom can be either a transition metal or rare-earth atom. |
| FILED | Monday, March 24, 2003 |
| APPL NO | 10/395993 |
| ART UNIT | 2832 — Printing/Measuring and Testing |
| CURRENT CPC | Inductor devices 336/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873415 | Amonette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | James E. Amonette (Richland, Washington); S. Thomas Autrey (West Richland, Washington); Nancy S. Foster-Mills (Richland, Washington); David Green (Dover, Massachusetts) |
| ABSTRACT | Methods and apparatus for analysis of multiple samples by photoacoustic spectroscopy are disclosed. Particularly, a photoacoustic spectroscopy sample array vessel including a vessel body having multiple sample cells connected thereto is disclosed. At least one acoustic detector is acoustically coupled with the vessel body. Methods for analyzing the multiple samples in the sample array vessels using photoacoustic spectroscopy are provided. |
| FILED | Tuesday, November 13, 2001 |
| APPL NO | 10/002624 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/432 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873454 | Barty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher P. J. Barty (Hayward, California); Igor Jovanovic (Oakland, California) |
| ABSTRACT | A hybrid chirped pulse amplification system wherein a short-pulse oscillator generates an oscillator pulse. The oscillator pulse is stretched to produce a stretched oscillator seed pulse. A pump laser generates a pump laser pulse. The stretched oscillator seed pulse and the pump laser pulse are directed into an optical parametric amplifier producing an optical parametric amplifier output amplified signal pulse and an optical parametric amplifier output unconverted pump pulse. The optical parametric amplifier output amplified signal pulse and the optical parametric amplifier output laser pulse are directed into a laser amplifier producing a laser amplifier output pulse. The laser amplifier output pulse is compressed to produce a recompressed hybrid chirped pulse amplification pulse. |
| FILED | Tuesday, November 26, 2002 |
| APPL NO | 10/304262 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873921 | Tucker, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Raymond W. Tucker, Jr. (Knoxville, Tennessee) |
| ABSTRACT | An improved method for detecting the presence of humans or animals concealed within in a vehicle uses a combination of the continuous wavelet transform and a ratio-based energy calculation to determine whether the motion detected using seismic sensors placed on the vehicle is due to the presence of a heartbeat within the vehicle or is the result of motion caused by external factors such as the wind. The method performs well in the presence of light to moderate ambient wind levels, producing far fewer false alarm indications. The new method significantly improves the range of ambient environmental conditions under which human presence detection systems can reliably operate. |
| FILED | Monday, September 29, 2003 |
| APPL NO | 10/673720 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06871527 | Hansma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Paul K. Hansma (Isla Vista, California); Barney Drake (Reno, Nevada); James Thompson (Ithaca, New York); Johannes H. Kindt (Santa Barabara, California); David Hale (Santa Barbara, California) |
| ABSTRACT | An improvement for atomic force microscopes, more generally for light beam detecting systems, but also in part applicable to scanning probe microscopes, providing significant novel features and advantages. Particular features include using different objective lens regions for incident and reflected light, a flexure that allows three dimensional motion of the optics block, forming the housing and optics block of a composite material or ceramic, arranging the components so that the beam never hits a flat surface at normal incidence, and providing a resonant frequency of cantilever vibration greater than 850 HZ between the cantilever and sample and the cantilever and focusing lens. |
| FILED | Wednesday, July 17, 2002 |
| APPL NO | 10/197771 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872403 | Pienkowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | David A. Pienkowski (Lexington, Kentucky); Rodney J. Andrews (Lexington, Kentucky) |
| ABSTRACT | An augmented synthetic resin is provided. That resin includes carbon nanotubes dispersed in a polymethylmethacrylate matrix. The method of preparing this synthetic resin includes the mixing and disaggregating of the carbon nanotubes. |
| FILED | Wednesday, January 31, 2001 |
| APPL NO | 09/773293 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872971 | Hutchinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The State of Oregon acting by and through the State Board of Higher Education on behalf of The University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | James E. Hutchinson (Eugene, Oregon); Scott M. Reed (Eugene, Oregon); Martin N. Wybourne (Hanover, New Hampshire) |
| ABSTRACT | A method for forming arrays of metal, alloy, semiconductor or magnetic clusters is described. The method comprises placing a scaffold on a substrate, the scaffold comprising, for example, polynucleotides and/or polypeptides, and coupling the clusters to the scaffold. Methods of producing arrays in predetermined patterns and electronic devices that incorporate such patterned arrays are also described. |
| FILED | Thursday, February 19, 2004 |
| APPL NO | 10/783515 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873020 | Misra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Veena Misra (Raleigh, North Carolina); Huicai Zhong (Raleigh, North Carolina); ShinNam Hong (Seoul, South Korea) |
| ABSTRACT | Integrated circuit electrodes include an alloy of a first metal and a second metal having lower work function than the first metal. The second metal also may have higher oxygen affinity than the first metal. The first metal may be Ru, Ir, Os, Re and alloys thereof, and the second metal may be Ta, Nb, Al, Hf, Zr, La and alloys thereof. Both NMOS and the PMOS devices can include gate electrodes of an alloy of the first metal and the second metal having lower work function than the first metal. The PMOS gate electrode may have a higher percentage of the first metal relative to the second metal than the NMOS gate electrode. Thus, a common material system may be used for gate electrodes for both NMOS and PMOS devices. |
| FILED | Friday, February 22, 2002 |
| APPL NO | 10/081861 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873163 | Bonnell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Dawn A. Bonnell (Media, Pennsylvania); Sergei V. Kalinin (Philadelphia, Pennsylvania); Rodolfo Antonio Alvarez (Philadelphia, Pennsylvania) |
| ABSTRACT | A scanning probe detects phase changes of a cantilevered tip proximate to a sample, the oscillations of the cantilevered tip are induced by a lateral bias applied to the sample to quantify the local impedance of the interface normal to the surface of the sample. An ac voltage having a frequency is applied to the sample. The sample is placed at a fixed distance from the cantilevered tip and a phase angle of the cantilevered tip is measured. The position of the cantilevered tip is changed relative to the sample and another phase angle is measured. A phase shift of the deflection of the cantilevered tip is determined based on the phase angles. The impedance of the grain boundary, specifically interface capacitance and resistance, is calculated based on the phase shift and the frequency of the ac voltage. Magnetic properties are measured by applying a dc bias to the tip that cancels electrostatic forces, thereby providing direct measurement of magnetic forces. |
| FILED | Friday, January 18, 2002 |
| APPL NO | 10/052024 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/719 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06874006 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Pentomics, Inc. (Pasadena, California) |
| INVENTOR(S) | Dengwei Fu (Santa Clara, California); Alan N. Willson, Jr. (Pasadena, California) |
| ABSTRACT | A rectangular-to-polar-converter receives a complex input signal (having X0 and Y0 components) and determines an angle φ that represents the position of the complex signal in the complex plane. The rectangular-to polar-converter determines a coarse angle φ1 and a fine angle φ2, where φ=φ1+φ2. The coarse angle φ1 is obtained using a small arctangent table and a reciprocal table. These tables provide just enough precision such that the remaining fine angle φ2 is small enough to approximately equal its tangent value. Therefore the fine angle φ2 can be obtained without a look-up table, and the fine angle computations are consolidated into a few small multipliers, given a precision requirement. Applications of the rectangular-to-polar converter include symbol and carrier synchronization, including symbol synchronization for bursty transmissions of packet data systems. Other applications include any application requiring the rectangular-to-polar conversion of a complex input signal. |
| FILED | Monday, October 30, 2000 |
| APPL NO | 09/698249 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/442 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 06872388 | Lartey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Robert T. Lartey (Sidney, Montana); TheCan Caesar (Sidney, Montana) |
| ABSTRACT | Disease in plants caused by infection with cercosporin producing strains of Cercospora may be controlled by application of laccase. When applied to the locus of the plant, or parts or seed thereof, the cercosporin toxin produced by this pathogen is degraded by the enzyme, thereby preventing or minimizing damage to the plant. The laccase may be applied alone, or in combination with one or more laccase-producing microorganisms. |
| FILED | Friday, July 26, 2002 |
| APPL NO | 10/205871 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872813 | Gross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth C. Gross (Ellicott City, Maryland); David L. Smith (Columbia, Maryland) |
| ABSTRACT | Novel DNA sequences derived from a family of genes encoding β-galactosidases in tomato are disclosed. β-Galactosidase II has demonstrated enzyme activity in cell wall disassembly, leading to loss of tissue integrity and fruit softening. Modification of β-galactosidase II gene expression in plants transformed for expression in the antisense direction results in improvement of the quality of fruit texture and firmness. |
| FILED | Tuesday, June 08, 1999 |
| APPL NO | 09/701868 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/23.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 06872432 | Wilson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Magna International of America, Inc. (Troy, Michigan) |
| INVENTOR(S) | Phillip S. Wilson (Commerce Township, Michigan) |
| ABSTRACT | A hollow, reinforced, molded automotive hard top is made using a sheet of thermoplastic material with nanoparticles dispersed therein. The particles comprise less than 15% of total volume of the plastic sheet, at least 50% of the particles have a thickness less than about 20 layers, and at least 99% of the particles have a thickness of less than about 30 layers. The sheet is preheated and molded in an assembly having mold surfaces corresponding to the hard top configuration. Vacuum is applied to one side of the assembly and pressurized gas is applied to the opposite side of the assembly to force the sheet into conformity with the mold surfaces. After cooling, the conformed sheet is transferred to another mold assembly, where a reinforced plastic melt having a blowing agent is applied. Together, the solidified melt and the conformed plastic sheet form the hard top. |
| FILED | Friday, August 16, 2002 |
| APPL NO | 10/219666 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Stock material or miscellaneous articles 428/36.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06872527 | Gerdes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | XTRANA, Inc. (Broomfield, Colorado) |
| INVENTOR(S) | John C. Gerdes (Denver, Colorado); Jeffery M. Marmaro (Aurora, Colorado); Jeffrey T. Ives (Arvada, Colorado); Christopher A. Roehl (Tampa, Florida) |
| ABSTRACT | This invention is directed to a process for tightly binding nucleic acid to solid phase and corresponding processes for the utilization thereof. Nucleic acid is bound to solid phase matrices exhibiting sufficient hydrophilicity and electropositivity to tightly bind the nucleic acids from a sample. These processes include nucleic acid (double or single stranded DNA and RNA) capture from high volume and/or low concentration specimens, buffer changes, washes, and volume reductions, and enable the interface of solid phase bound nucleic acid with enzyme, hybridization or amplification strategies. The tightly bound nucleic acid may be used, for example, in repeated analyses to confirm results or test additional genes in both research and commercial applications. Further, a method is described for virus extraction, purification, and solid phase amplification from large volume plasma specimens. |
| FILED | Friday, August 31, 2001 |
| APPL NO | 09/944604 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 06871563 | Choset et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Howie Choset (Pittsburgh, Pennsylvania); Elie Shammas (Pittsburgh, Pennsylvania) |
| ABSTRACT | An orientation preserving angular swivel joint suitable for mechanical robotic arms and in particular snake robots, the joint comprising two members and an angular bevel gear train that connects the two members of the joint. The gear train allows an actuator to be positioned along the axis of the joint while transferring forces to the periphery of the mechanism, thus creating a high mechanical advantage proportional to the radius of the robot. The gear train is capable of transferring rotational motion between the two members with a constant ratio. Relative rotation between two bays of the joint does not take place, thereby preventing electrical wires running through the body of the snake from being twisted, and thus avoiding failure. |
| FILED | Tuesday, February 26, 2002 |
| APPL NO | 10/083705 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Machine element or mechanism 074/490.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06873762 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Ying Wang (Albuquerque, New Mexico); Anup Sharma (Huntsville, Alabama); Joseph Grant (Meridianville, Alabama) |
| ABSTRACT | An apparatus and method for forming a Bragg grating on an optical fiber using a phase mask to diffract a beam of coherent energy and a lens combined with a pair of mirrors to produce two symmetrical virtual point sources of coherent energy in the plane of the optical fiber. The two virtual light sources produce an interference pattern along the optical fiber. In a further embodiment, the period of the pattern and therefore the Bragg wavelength grating applied to the fiber is varied with the position of the optical fiber relative the lens. |
| FILED | Monday, April 08, 2002 |
| APPL NO | 10/118626 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Optical waveguides 385/37 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 06872504 | Fedynyshyn |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Theodore H. Fedynyshyn (Sudbury, Massachusetts) |
| ABSTRACT | The present invention provides methods for lithography utilizing X-ray radiation. More particularly, the methods of the invention can be employed for lithography at wavelengths in a range between about 0.8 nm and 30 nm, and more particularly, at wavelengths in a range between 0.8 and 1.2 nm. The methods of the invention employ photoresist compositions having fluorinated polymers with a fluorine content of at least about 10% by weight to provide enhanced sensitivity for X-ray lithography. |
| FILED | Tuesday, December 10, 2002 |
| APPL NO | 10/315356 |
| ART UNIT | 1752 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 06871563 | Choset et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Howie Choset (Pittsburgh, Pennsylvania); Elie Shammas (Pittsburgh, Pennsylvania) |
| ABSTRACT | An orientation preserving angular swivel joint suitable for mechanical robotic arms and in particular snake robots, the joint comprising two members and an angular bevel gear train that connects the two members of the joint. The gear train allows an actuator to be positioned along the axis of the joint while transferring forces to the periphery of the mechanism, thus creating a high mechanical advantage proportional to the radius of the robot. The gear train is capable of transferring rotational motion between the two members with a constant ratio. Relative rotation between two bays of the joint does not take place, thereby preventing electrical wires running through the body of the snake from being twisted, and thus avoiding failure. |
| FILED | Tuesday, February 26, 2002 |
| APPL NO | 10/083705 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Machine element or mechanism 074/490.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 06871565 | Allaei |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Quality Research, Development and Consulting, Inc. (Chaska, Minnesota) |
| INVENTOR(S) | Daryoush Allaei (Excelsior, Minnesota) |
| ABSTRACT | A method for controlling vibration energy in a structure having a vibrating member using a vibration confinement device is provided. The vibrating member has boundaries and vibrates relative to the boundaries. The method includes selecting a vibration confinement region in the vibrating member relative to the boundaries. Determining an effective torsional stiffness and an effective translational stiffness for the vibration confinement device is included in the method. The method includes determining an operating position relative to the boundaries for the vibration confinement device on the vibrating member to define a determined position. The method includes positioning the vibration confinement device at the determined position to substantially confine the vibration energy to the vibration confinement region. |
| FILED | Friday, October 17, 2003 |
| APPL NO | 10/688462 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Machine element or mechanism 074/574 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 06872971 | Hutchinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The State of Oregon acting by and through the State Board of Higher Education on behalf of The University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | James E. Hutchinson (Eugene, Oregon); Scott M. Reed (Eugene, Oregon); Martin N. Wybourne (Hanover, New Hampshire) |
| ABSTRACT | A method for forming arrays of metal, alloy, semiconductor or magnetic clusters is described. The method comprises placing a scaffold on a substrate, the scaffold comprising, for example, polynucleotides and/or polypeptides, and coupling the clusters to the scaffold. Methods of producing arrays in predetermined patterns and electronic devices that incorporate such patterned arrays are also described. |
| FILED | Thursday, February 19, 2004 |
| APPL NO | 10/783515 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 06872547 | Curtiss, III |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Roy Curtiss, III (St. Louis, Missouri) |
| ABSTRACT | The invention encompasses methods of maintaining desired recombinant genes in a genetic population of cells expressing the desired gene. The methods utilize microbial cells that have an inactivating mutation in a native essential gene encoding an enzyme which catalyzes a step in the biosynthesis of diaminopimelic acid (DAP). The cells also have an extrachromosomal vector that includes the desired gene and which is capable of homologous recombination with a chromosome of the microorganism. The vector also has a recombinant complementing gene encoding a functional replacement of the native essential gene. The cells of the invention are particularly useful for components of vaccines, including DNA vaccines. |
| FILED | Wednesday, October 11, 2000 |
| APPL NO | 09/686499 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06873156 | Ferris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Insight Neuroimaging Systems, LLC (Worcester, Massachusetts) |
| INVENTOR(S) | Craig F. Ferris (Holden, Massachusetts); Jean A King (Worcester, Massachusetts); Arthur C. Allard (Templeton, Massachusetts); Reinhold Ludwig (Paxton, Massachusetts); Gene Bogdanov (Manchester, Connecticut) |
| ABSTRACT | The present invention relates to systems and methods of performing magnetic resonance imaging (MRI) in awake animals. The invention utilizes head and body restrainers to position an awake animal relative to a radio frequency dual coil system operating in a high field magnetic resonance imaging system to provide images of high resolution without motion artifact. |
| FILED | Thursday, February 13, 2003 |
| APPL NO | 10/365952 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/318 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 29, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050329.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page