FedInvent™ Patents

Patent Details for Tuesday, April 26, 2005 

This page was updated on Sunday, March 26, 2023 at 07:46 PM GMT

Department of Defense (DOD) 

US 06883390 Cavanagh
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Richard A. Cavanagh (Panama City, Florida)
ABSTRACT A system measures dynamic force of an impacting spray of air and water. A pitot-tube section is aligned to receive a longitudinal flow of impacting air/water spray in a laterally extending orifice. A first differential pressure transducer is coupled to the pitot-tube section for producing signals representative of velocity of the air/water spray at the orifice. A rain gage section adjacent to the pitot-tube section receives and collects volumes of water of the longitudinal flow of air/water spray through a laterally extending opening. A second pressure differential transducer is coupled to the rain gage section to produce signals representative of the volumes of water collected in the rain gage section. A computer-based control/readout module receives the velocity representative signals and water volume representative signals for indicating the magnitude of dynamic force attributed to impacting air/water spray in the opening.
FILED Thursday, December 18, 2003
APPL NO 10/738333
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/861.650
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06883452 Gieseke
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thomas J. Gieseke (Newport, Rhode Island)
ABSTRACT A towed antenna system and method of use includes a communication device disposed on a buoyant body attached to a housing by a tether. The housing includes a spool, a reel-wire guide, and a motor. The buoyant body and the reel housing are deployed from and towed at from a submerged platform. Hydrodynamic forces from towing prevent the buoyant body from rising to the surface while maintaining the housing at an equilibrium depth. To establish communication, the tether is released from the spool and the buoyant body rises to the surface. The tether is released until the communication session is over or until the tether is fully deployed. The reel-wire guide prevents the tether from becoming snagged during release. Once the communication session has been completed, the tether is retracted and the buoyant body re-establishes its equilibrium depth.
FILED Monday, October 06, 2003
APPL NO 10/679675
ART UNIT 3617 — Printing/Measuring and Testing
CURRENT CPC
Ships
114/244
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06883453 Mulhern
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Francis M. Mulhern (Riverton, New Jersey)
ABSTRACT An underwater retrieval body connected at its forward bow end by a towing line to a retrieval ship, has attachment facilities at its opposite aft end for attachment thereof during underwater propulsion with an unmanned watercraft by engaging its projecting hook or reception of a projecting probe. During propulsion of the underwater retrieval body toward the unmanned watercraft, it is maneuvered into alignment therewith through steering rudder fins under control of a homing control system on the underwater retrieval body, in response to reception of tracking signals emitted from the unmanned watercraft.
FILED Monday, April 19, 2004
APPL NO 10/826903
ART UNIT 3617 — Printing/Measuring and Testing
CURRENT CPC
Ships
114/253
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06883761 Boon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Brian Frederick Boon (North Andover, Maryland);  Daniel D. Smith (Mason, Ohio)
ABSTRACT A two-piece clamping arrangement for engaging and holding an elongated element, such as a tubular conduit for fluids, or the like. An upper and a lower clamp member are provided to engage oppositely-facing surfaces of the elongated element. One of the upper or lower clamp members includes at least one longitudinally-arranged alignment surface to assure proper alignment of the clamp members when the clamp is assembled about the elongated element. The alignment surface also serves to stiffen the clamp member against bending and thereby serves to increase the holding force of the clamp assembly.
FILED Thursday, February 13, 2003
APPL NO 10/366159
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Supports
248/74.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884025 Pickens et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) John T. Pickens (East Hartford, Connecticut);  Phillip Alexander (Colchester, Connecticut);  Anthony R. Bifulco (Ellington, Connecticut);  Kevin J. Cummings (West Hartford, Connecticut)
ABSTRACT The present invention relates to a bumper system for use with a compressor variable vane system. The bumper system broadly comprises a synchronizing ring, a bumper, a shim for defining a gap between a bumper pad and the bumper, a pin for preventing rotation of the bumper relative to the synchronizing ring, and a device for fully trapping the shim. In a first embodiment, the device for fully trapping the shim comprises a sleeve passing through the synchronizing ring. In a second embodiment, the device for fully trapping the shim comprises a pin which passes through the synchronizing body. In a third embodiment, the device for fully trapping the shim comprises a fastener with a shoulder.
FILED Monday, September 30, 2002
APPL NO 10/261471
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/160
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884026 Glynn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Christopher Charles Glynn (Hamilton, Ohio);  Mary Ellen Alford (Cincinnati, Ohio);  Mark Eugene Noe (Morrow, Ohio);  Toby George Darkins, Jr. (Loveland, Ohio)
ABSTRACT At least one shroud segment, floating axially independently of adjacent turbine engine shroud assembly members, includes a segment body comprising a radially outer surface and a radially outwardly projecting segment support that includes an axial support wall surface therein. The assembly includes a shroud hanger in axial juxtaposition with the segment support, and at least one axial support projection from the shroud hanger into the segment support at the support wall surface. The support projection supports the shroud segment releasably at the support wall surface sufficiently to enable relative axial movement of the shroud segment on the support projection independently of the shroud hanger and adjacent engine members.
FILED Monday, September 30, 2002
APPL NO 10/260478
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/173.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884093 Baldo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Marc Baldo (Princeton, New Jersey);  Peter Peumans (Princeton, New Jersey);  Stephan Forrest (Princeton, New Jersey);  Changsoon Kim (Princeton, New Jersey)
ABSTRACT An organic semiconductor device is provided. The device has a first electrode and a second electrode, with an organic semiconductor layer disposed between the first and second electrodes. An electrically conductive grid is disposed within the organic semiconductor layer, which has openings in which the organic semiconductor layer is present. At least one insulating layer is disposed adjacent to the electrically conductive grid, preferably such that the electrically conductive grid is completely separated from the organic semiconductor layer by the insulating layer. Methods of fabricating the device, and the electrically conductive grid in particular, are also provided. In one method, openings are formed in an electrically conductive layer with a patterned die, which is then removed. In another method, an electrically conductive layer and a first insulating layer are etched through the mask to expose portions of a first electrode. In yet another method, a patterned die is pressed into a first organic semiconductor layer to create texture in the surface of the first organic semiconductor layer, and then removed. An electrically conductive material is then deposited onto the first organic semiconductor layer from an angle to form a grid having openings as a result of the textured surface and the angular deposition. In each of the methods, insulating layers are preferably deposited or otherwise formed during the process to completely separate the electrically conductive layer from previously and subsequently deposited organic semiconductor layers.
FILED Tuesday, September 17, 2002
APPL NO 10/246508
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Electrical connectors
439/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884478 Alivisatos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) A. Paul Alivisatos (Oakland, California);  Liang-shi Li (Berkeley, California)
ABSTRACT Semiconductor liquid crystal compositions and methods for making such compositions are disclosed. One embodiment of the invention is directed to a liquid crystal composition including a solvent and semiconductor particles in the solvent. The solvent and the semiconductor particles are in an effective amount in the liquid crystal composition to form a liquid crystal phase.
FILED Wednesday, October 23, 2002
APPL NO 10/280135
ART UNIT 1756 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Stock material or miscellaneous articles
428/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884551 Fritze et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Michael Fritze (Acton, Massachusetts);  Brian Tyrrell (Pawtucket, Rhode Island)
ABSTRACT A method forms patterns on a substrate by exposing the substrate a first time and exposing the substrate a second time using a mask containing gray-tone features. The gray-tone features locally adjust an exposure dose in regions corresponding to features defined in the primary exposure. Moreover, the gray-tone features enable the forming of features having different critical dimensions on a substrate. The gray-tone features may be sub-resolution features and formed by pixellation. The trim mask containing gray-tone features may have regions with different transmissivities.
FILED Wednesday, September 04, 2002
APPL NO 10/234783
ART UNIT 1756 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884573 Fischer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  East Carolina University (Greenville, North Carolina)
INVENTOR(S) Thomas H. Fischer (Hillsborough, North Carolina);  Marjorie S. Read (Durham, North Carolina);  Arthur P. Bode (Greenville, North Carolina);  Timothy C. Nichols (Chapel Hill, North Carolina)
ABSTRACT Fixed-dried red blood cells (RBCs), and processes for preparing the same are disclosed. The red blood cells, upon reconstitution with distilled water or appropriate buffer: bind oxygen with native affinities, have partial deformability, present minimal thrombogenicity to platelets, and have oblated blood group antigens. The RBCs are preferably fixed by means of cross-linkers with aldehyde functions such as paraformaldehyde or glutaraldehyde either alone or in combination. Native oxygen kinetics are achieved by preparing the red blood cells with 1,6-diphosphofructose. Blood group antigens and chemical functions that render the lyophilized RBCs thrombogenic are occluded by chemically attaching polyoxyethylene glycol polymers to the surface membrane of the red blood cells. The cross-linked red blood cells are preferably died by lyophilization.
FILED Friday, August 30, 2002
APPL NO 10/231635
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884588 Rastogi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Vipin K. Rastogi (Bel Air, Maryland);  Tu-Chen Cheng (Timonium, Maryland)
ABSTRACT The invention provides purified and isolated DNA fragments from Bacillus anthracis chromosomal DNA, primer sets and probes derived therefrom, as well as kits and detection methods for B. anthracis. The methods of the invention provide for specific detection of anthrax over closely related strains of Bacillus, as well as accurate detection of low numbers of B. anthracis in an environmental sample containing large amounts of non-specific DNA. The invention is applicable to food, health care, and military applications.
FILED Monday, September 09, 2002
APPL NO 10/237913
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884630 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Infineon Technologies AG (Munich, Germany);  Internation Business Machines Corporation (Armonk, New York)
INVENTOR(S) Arunava Gupta (Valley Cottage, New York);  Kia-Seng Low (Hopewell Junction, New York)
ABSTRACT Magnetic tunnel junction devices can be fabricated using a two-step deposition process wherein respective portions of the magnetic tunnel junction stack are defined independently of one another.
FILED Tuesday, January 21, 2003
APPL NO 10/348235
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884640 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeffrey J. Peterson (Austin, Texas);  Charles E. Hunt (Davis, California);  Peter J. Bjeletich (Davis, California)
ABSTRACT One embodiment of the present invention provides a system that determines the composition of a layer within an integrated device. The system operates by first receiving the integrated device. Next, the system measures properties of the layer using electromagnetic radiation. The properties of the layer measured are used to determine an index of refraction for the layer. The system then solves for the composition of the layer using the index of refraction.
FILED Tuesday, May 13, 2003
APPL NO 10/437878
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884717 Desalvo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Gregory C. Desalvo (Bellbrook, Ohio);  Tony K. Quach (Lebanon, Ohio);  John L. Ebel (Beavercreek, Ohio);  Anders P. Walker (Wilmington, Ohio);  Paul D. Cassity (Covington, Ohio)
ABSTRACT An etching based semiconductor wafer thinning arrangement usable as an improved alternative to the usual grinding and polishing wafer thinning. The thinned wafer includes a structurally enhancing wafer backside grid array of original wafer thickness semiconductor material with grid cells surrounding individual thinned wafer areas and serving to improve the strength and physical rigidity characteristics of the thinned wafer. Preferably this grid array is supplemented with an additional, wafer periphery-located, backside ring of semiconductor material also of original wafer thickness. Ability to avoid a wafer front side mounting during thinning accomplishment, fast etching, reduced wafer breakage, enhanced wafer strength and improved wafer handling achieved with the disclosed thinning arrangement all contribute to achieved advantages over conventional wafer thinning. Gallium arsenide or other semiconductor materials are contemplated along with use in radio frequency or other integrated circuit devices of either the single transistor or complete integrated circuit components types.
FILED Thursday, January 03, 2002
APPL NO 10/034723
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/667
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884732 Najafi et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Khalil Najafi (Ann Arbor, Michigan);  Chou Tsung-Kuan (San Jose, California)
ABSTRACT A method of fabricating a device having a desired non-planar surface or profile and device produced thereby are provided. A silicon wafer is first coated with silicon nitride, patterned, and DRIE to obtain the desired etch profile. Silicon pillars between trenches are then etched using an isotropic wet etch, resulting in a curved well. The wafer is then oxidized to −2 μm to smooth the surface of the well, and to protect the well from an ensuing planarization process. The nitride is then selectively removed, and the wafer surface is planarized by removing the Si left in the field regions using either a maskless DRIE or CMP. Finally, the oxide is etched away to produce a wafer with a curved surface.
FILED Friday, October 11, 2002
APPL NO 10/269256
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/713
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884740 Hu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Evelyn L. Hu (Goleta, California);  Andreas R. Stonas (Goleta, California)
ABSTRACT Photoelectrochemical (PEC) etching is restricted to a group III nitride semiconductor-barrier interface to laterally etch or undercut the target group III nitride. The barrier interface is provided by the transparent sapphire substrate on which the target group III nitride is epitaxially grown or by a layer of material in intimate contact with the target group III nitride material and having a bandgap sufficiently high to make it resistant to PEC etching. Due to the first orientation in which this effect was first observed, it has been named backside-Illuminated photoelectrochemical (BIPEC) etching. It refers to a preferential etching at the semiconductor-barrier layer interface. The assembly can be exposed to light from any direction to effectuate bandgap-selective PEC etching. An opaque mask can be applied to limit the lateral extent of the photoelectrochemical etching.
FILED Tuesday, September 03, 2002
APPL NO 10/234535
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/962
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884861 Keller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Teddy M. Keller (Fairfax Station, Virginia);  Joseph Perrin (Centerville, Virginia);  Syed B. Qadri (Fairfax Station, Virginia)
ABSTRACT The present invention provides for a composition comprising: a composition formed by heating to a temperature of from about 300° C. and above a mixture of: an organometallic composition and an aromatic-acetylene containing compound; and wherein said organometallic composition comprises the formula:  wherein A is selected from the group consisting of H,
and wherein M is a metal; wherein Rx and Ry are independently selected from the group consisting of an aromatic, a substituted aromatic group and combinations thereof; wherein m, s and z are ≧0; wherein m and s are independently determined in each repeating unit; wherein said aromatic-acetylene containing composition is 1,2,4,5-tetrakis(phenylethynyl)benzene, 1,2,4-tris(phenylethynyl)benzene or 1,3,5-tris(phenylethynyl)benzene; and wherein said organometallic composition and said aromatic-acetylene composition are molar mix proportions of between 1 and 99 of said organometallic composition and between 99 and 1 of said aromatic-acetylene composition.
FILED Monday, December 10, 2001
APPL NO 10/006385
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
526/285
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884982 Beusch
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) John U. Beusch (Stow, Massachusetts)
ABSTRACT An electronic imager includes a detector array, a plurality of processing circuits, each responsive to an output signal from a respective detector element of the array and to a determination that signal coupling in general or charge sharing in particular occurred. The imager further includes a shared channel circuit coupled to at least two processing circuits for receiving an output signal from the processing circuits in response to a determination that signal coupling has occurred and for generating an output signal in response to the received signals. The shared channel circuit further directs the output signal to an image sub-pixel, wherein a plurality of sub-pixels are associated with each radiation sensitive element.
FILED Tuesday, February 19, 2002
APPL NO 10/078231
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885147 Howard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) eMagin Corporation (Hopewell Junction, New York)
INVENTOR(S) Webster E. Howard (Lagrangeville, New York);  Gary W. Jones (Lagrangeville, New York);  Richard A. Campos (Cortlandt Manor, New York);  Chen-Jean Chou (New City, New York)
ABSTRACT The present invention relates to OLED devices having anodes with improved stability and longer lifetime. In particular, the present invention relates to OLEDs comprising an anode having improved stability and longer lifetime wherein the anode comprises a semi-transparent single layer comprising molybdenum.
FILED Tuesday, July 31, 2001
APPL NO 09/919467
ART UNIT 2879 — Optics
CURRENT CPC
Electric lamp and discharge devices
313/504
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885504 Hall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Randolph L. Hall (Newbury Park, California);  William H. Southwell (Thousand Oaks, California)
ABSTRACT A complementary comb filter pair, and method for making same, are described, wherein each comb filter element of the complementary pair can be fabricated during the same deposition run. The complementary comb filter is masked so as to retard the thin film growth of the coating, for example, a dielectric material, so as to produce a desired wavelength transmission profile.
FILED Monday, June 11, 2001
APPL NO 09/878816
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/580
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885762 Saha et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Punam Kumar Saha (Philadelphia, Pennsylvania);  Jayaram K. Udupa (Audobon, Pennsylvania)
ABSTRACT The invention provides novel scale-based filtering methods that use local structure size or “object scale” information to arrest smoothing around fine structures and across even low-gradient boundaries. One method teaches a weighted average over a scale-dependent neighborhood; while another employs scale-dependent diffusion conductance to perform filtering. Both methods adaptively modify the degree of filtering at any image location depending on local object scale. This permits a restricted homogeneity parameter to be accurately used for filtering in regions with fine details and in the vicinity of boundaries, while at the same time, a generous filtering parameter is used in the interiors of homogeneous regions.
FILED Wednesday, February 07, 2001
APPL NO 09/779032
ART UNIT 2625 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/131
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885970 Petrovic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Vladan Petrovic (West Roxbury, Massachusetts);  Alex M. Stankovic (Boston, Massachusetts)
ABSTRACT A method and system for the sensorless estimation of the states of the mechanical subsystem of a motor are disclosed. In particular, the method and system split the estimation problem into two sub-problems: the estimation of motor parameters as a function of position, and the determination of the states of the mechanical subsystem of the motor using the estimated parameters via a state observer. Motor current and PWM voltage in a polyphase system is measured or otherwise determined and converted into current and voltage in α-β coordinates. A least square estimator is constructed that uses the voltage and current in α-β coordinates and provides an estimate of the motor parameters, and in particular, the inductances of the motor, which are a function of the rotor position. These estimated inductances are used to drive a state observer whose dynamics have been selected to provide as an output the state of the mechanical subsystem of the motor, and in particular, the position, velocity, and acceleration of this subsystem.
FILED Thursday, March 20, 2003
APPL NO 10/394504
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/169
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06886010 Kostoff
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ronald N. Kostoff (Arlington, Virginia)
ABSTRACT Text searching is achieved by techniques including phrase frequency analysis and phrase-co-occurrence analysis. In many cases, factor matrix analysis is also advantageously applied to select high technical content phrases to be analyzed for possible inclusion within a new query. The described techniques may be used to retrieve data, determine levels of emphasis within a collection of data, determine the desirability of conflating search terms, detect symmetry or asymmetry between two text elements within a collection of documents, generate a taxonomy of documents within a collection, and perform literature-based problem solving. (This abstract is intended only to aid those searching patents, and is not intended to limit the disclosure of claims in any manner.)
FILED Friday, August 22, 2003
APPL NO 10/645633
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/3
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 06884413 Shearer et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Gene M. Shearer (Bethesda, Maryland);  Jian-Ping Zuo (Shanghai, China PRC);  John E. Coligan (Potomac, Maryland);  Claire Chougnet (Batimore, Maryland)
ABSTRACT The present invention concerns methods of specifically inhibiting an immune response of a subject to one or more selected antigens using an immunosuppressive composition derived from a glioblastoma cell line. The method steps include obtaining a population of antigen presenting cells (APCs); loading the APC population with specific antigens (in auto-immune diseases) or using donor APCs (for transplantation); incubating the APC population with the immunosuppressive composition; and introducing the incubated cells into the subject being treated. The APCs can be monocytes, macrophages, or dendritic cells. This method causes specific inhibition of the immune response because it induces apoptosis and/or anergy in the subject's T cells specific for antigens present on the APCs, but does not affect the immune response to antigens not present on the APC surfaces. One particular embodiment of the present method is the specific inhibition of a transplant recipient's immune reaction to antigens present on the allogenic graft. A second particular embodiment of the present method is the specific inhibition of the immune response to an autoantigenic protein by a subject suffering from an autoimmune disease.
FILED Thursday, March 23, 2000
APPL NO 09/936537
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884414 Palese et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) Mount Sinai School of Medicine of New York University (New York, New York);  The United State of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Peter Palese (Leonia, New Jersey);  Adolfo Garcia-Sastre (New York, New York);  Nicholas F. Restifo (Washington, District of Columbia)
ABSTRACT The present invention relates to the engineering of recombinant influenza viruses that express tumor-associated antigens. Expression of tumor-associated antigens by these viruses can be achieved by engineering specific epitopes into influenza virus proteins, or by engineering viral genes that encode a viral protein and the specific antigen as independent polypeptides. Tumor-bearing patients can be immunized with the recombinant influenza viruses alone, or in combination with another treatment, to induce an immune response that leads to tumor reduction. The recombinant viruses can also be used to vaccinate high risk tumor-free patients to prevent tumor formation in vivo.
FILED Thursday, April 30, 1998
APPL NO 09/070629
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884417 Kirkland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Theo Kirkland (La Jolla, California);  Peter Tobias (San Diego, California);  Richard Ulevitch (Del Mar, California);  Ann Moriarty (Poway, California);  Didier Leturcq (San Diego, California)
ABSTRACT The present invention concerns a method of treating LBP-mediated LPS-induced myeloid cell activation comprising administering a therapeutically effective amount of an anti-LBP monoclonal antibody molecule. A therapeutic composition comprising anti-LBP antibody molecules in a pharmaceutically acceptable excipient is also contemplated.
FILED Tuesday, May 15, 2001
APPL NO 09/858279
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/137.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884432 Yaszemski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Michael J. Yaszemski (Rochester, Minnesota);  Bradford L. Currier (Rochester, Minnesota);  Lichun Lu (Rochester, Minnesota);  Xun Zhu (Rochester, Minnesota);  Esmaiel Jabbari (Rochester, Minnesota);  Diederik H. R. Kempen (Utrecht, Netherlands)
ABSTRACT Microspheres for controlled release of a bioactive agent are disclosed, and in particular, blend, cross-linkable poly(propylene fumarate) for immobilization and controlled drug delivery. The microsphere includes poly(propylene fumarate), a polymeric material other than poly(propylene fumarate) (e.g., poly(lactic-co-glycolic acid)), and a bioactive agent. The bioactive agent is selected depending on the physiological effect desired. For example, in bone regeneration applications, the bioactive agent may be selected from osteoinductive agents, peptides, growth hormones, osteoconductive agents, cytokines and mixtures thereof. The bioactive agent is dispersed in the microsphere, the microsphere has a diameter in the range of 1 to 300 micrometers, the poly(propylene fumarate) and poly(lactic-co-glycolic acid) are distributed in the microsphere, and the microsphere releases the bioactive agent in a sustained manner after an initial burst release. The microspheres may be covalently attached to a poly(propylene fumarate) scaffold for tissue regeneration applications in which the bioactive agent is released from the scaffold.
FILED Friday, April 25, 2003
APPL NO 10/423209
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/460
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884585 Levine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Fred Levine (Del Mar, California);  Dominique Dufayet (San Diego, California)
ABSTRACT The present invention provides methods for inducing insulin gene expression in cultured pancreas cells, the method comprising contacting a culture of endocrine pancreas cells expressing a PDX-1 gene with a GLP-1 receptor agonist, wherein the cells have been cultured under conditions such that the cells are in contact with other cells in the culture, thereby inducing insulin gene expression in the cells. The invention also provides high throughput screening methods for modulators of β-cell function, stable cultures of cells made by the methods of the invention, and methods of treating a human subject using the methods of the invention.
FILED Thursday, May 30, 2002
APPL NO 10/160336
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884589 Kamps et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of California (Oakland, California)
INVENTOR(S) Mark P. Kamps (Carlsbad, California);  David B. Sykes (La Jolla, California)
ABSTRACT The invention is a genetic construct comprising the coding sequence for a hormone dependent E2a-Pbx1 protein. The invention is the use of the construct to generate hematopoietic cell lines arrested in differentiation upon exposure to the appropriate hormone. Upon removal of the hormone, cells undergo normal, synchronous differentiation providing a system for the study of normal differentiation. Expression of a number of oncogenes in the cells maintains the cells in an undifferentiated state, providing a model for the study the mechanisms of leukemia, and for the testing of pharmacological agents for the treatment and amelioration of the disease.
FILED Friday, November 30, 2001
APPL NO 10/432057
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884590 Rotter et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Jerome I. Rotter (Los Angeles, California);  Stephan R. Targan (Los Angeles, California);  Huiying Yang (Cerritos, California);  Arthur L. Beaudet (Houston, Texas);  Devendra Vora (Torrance, California)
ABSTRACT A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by, R241 allele and kits which exploit the inventive methods.
FILED Friday, October 15, 1999
APPL NO 09/419408
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884595 Allen-Hoffmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) B. Lynn Allen-Hoffmann (Madison, Wisconsin);  Sandra J. Schlosser (Oregon, Wisconsin)
ABSTRACT A spontaneously immortalized human keratinocyte cell line is disclosed. In a preferred embodiment, this cell line is ATCC 12191. In another embodiment of the invention, a method of assaying the effect of a test tumor cell modulation agent is disclosed. The method comprises the steps of obtaining a human stratified squamous epithelial cell culture, wherein the culture comprises human malignant squamous epithelial cells and spontaneously immortalized human keratinocytes, wherein the culture forms a reconstituted epidermis. One then treats the epidermis with a test tumor cell modulation agent and evaluates the growth of the malignant cells within the epidermis.
FILED Tuesday, November 19, 2002
APPL NO 10/299938
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884596 Civelli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Olivier Civelli (Irvine, California);  Steven Lin (Upland, California)
ABSTRACT The invention provides methods of screening for a compound for promoting wakefulness in a mammal. The method is practiced by providing a compound that is a PrRP receptor agonist and determining the ability of the compound to promote wakefulness. Also provided by the invention are methods of screening for a compound for promoting sleep in a mammal. The methods are practiced by providing a compound that is a PrRP receptor antagonist and determining the ability of the compound to promote sleep. In addition, the invention provides a method of promoting wakefulness in a mammal. The method is practiced by administering to a mammal an effective amount of a PrRP receptor agonist. The invention further provides a method of promoting sleep in a mammal. The method is practiced by administering to a mammal an effective amount of a PrRP receptor antagonist.
FILED Friday, August 17, 2001
APPL NO 09/932161
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884603 Debinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (, Pennsylvania)
INVENTOR(S) Waldemar Debinski (Hershey, Pennsylvania);  Jeffrey P. Thompson (Landisville, Pennsylvania)
ABSTRACT This invention provides nucleic acid molecules encoding mutant human interleukin 13 molecules showing varying specificity for the restricted (IL4 independent) IL13 receptor. The mutant hIL13 molecules include those made by substituting the amino acid residues that occur in the alpha-helix regions of native hIL13 with various other amino acid residues. Some of the mutants retain the ability to bind and cause signaling through IL13 receptors, while other mutants do not.
FILED Thursday, January 17, 2002
APPL NO 10/053406
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.520
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884604 Thorson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S) Jon S. Thorson (Madison, Wisconsin)
ABSTRACT The present invention provides combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. The glycosyltransferase may be one that is associated with or involved in production of natural secondary metabolites, or one which is putatively associated with or involved in production of natural secondary metabolites. The glycosyltransferase may show significant flexibility with respect to its NDP-sugar donors and/or its aglycons. NDP-sugar donors may be commercially available, or may be produced by utilizing mutant or wild type nucleotidyltransferases significant flexibility with respect to their substrates.
FILED Monday, April 01, 2002
APPL NO 10/109672
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/89
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884613 Le Doux et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Joseph M. Le Doux (Decatur, Georgia);  Martin L. Yarmush (Newton, Massachusetts);  Jeffrey R. Morgan (Sharon, Massachusetts)
ABSTRACT The invention provides new methods for purifying and concentrating viruses. The inventors have discovered that high molecular weight proteoglycans present in retroviral stocks are co-concentrated with the retroviruses, and can inhibit retroviral transduction. The new purification and concentration methods feature treatment of virus stock with an anionic polyelectrolyte and a cationic polyelectrolyte, followed by centrifugation. The new methods minimize the amount of proteoglycan co-precipitated with the infectious virus.
FILED Friday, August 24, 2001
APPL NO 09/939065
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/239
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884619 Hockfield et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Susan Hockfield (North Haven, Connecticut);  Russell T. Matthews (New Haven, Connecticut)
ABSTRACT The present invention relates to primary CNS tumors and provides useful compositions and methods for reducing tumor volume and increasing the length of survival in mammals with primary CNS tumors, thereby providing a treatment for primary CNS tumors. The invention also relates to methods of identifying compounds for reducing tumor volume and increasing animal survival, which therefore relate to treating primary CNS tumors.
FILED Tuesday, July 16, 2002
APPL NO 10/195970
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884773 Stamler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Jonathan S. Stamler (Chapel Hill, North Carolina);  Andrew J. Gow (Doylestown, Pennsylvania)
ABSTRACT Diseases which can be ameliorated by delivery of NO to tissues affected by the disease can be treated by administration of nitrosyl-heme-containing donors of NO, including nitrosylhemoglobin. Nitrosylhemoglobin can be made by the reaction of NO with hemoglobin under certain conditions in which the NO:hemoglobin ratio is critical, and is converted to SNO-Hb under physiological conditions.
FILED Thursday, February 06, 1997
APPL NO 08/796164
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884775 Tabin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Imperial Cancer Research Technology, Inc. (London, United Kingdom)
INVENTOR(S) Clifford J. Tabin (Cambridge, Massachusetts);  Andrew P. McMahon (Lexington, Massachusetts);  Philip W. Ingham (Summertown, United Kingdom);  Andrea M. Vortkamp (Boston, Massachusetts)
ABSTRACT The present application is directed to the discovery that hedgehog proteins, and agents which effect the activities thereof, can be used to control the formation and/or maintenance of cartilage and bone.
FILED Friday, August 01, 1997
APPL NO 08/905572
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884778 Jo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Seongbong Jo (Houston, Texas);  Antonios G. Mikos (Houston, Texas)
ABSTRACT A new oligomer based on alternating fumaric acid and poly(ethylene glycol) (PEG) units is provided. The oligo(PEG fumarate) (OPF) may be functionalized by modification with a biocompatible organic group. Further, the OPF may be cross-linked using radical polymerization in the presence of either a chemical or photo initiator. A cross-linked OPF gel has a swelling behavior that is tunable dependent on the molecular weight of PEG. A cross-linkable PEG macromer, as exemplified by oligo(PEG fumarate), has unsaturated double bonds, for example in the fumaryl groups, along its macromolecular chain that allows for the preparation of hydrogels with tailored structure and properties.
FILED Monday, April 30, 2001
APPL NO 09/845570
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884781 Wang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Ping Wang (Roslyn, New York)
ABSTRACT Methods of treating a mammal in shock or at risk for shock are provided. The methods involve administration of an adrenomedullin binding protein-1 to the mammal. Also provided are methods of preventing or treating a physiologic effect of shock in a mammal. These methods also involve administration of an adrenomedullin binding protein-1 to the mammal.
FILED Friday, December 05, 2003
APPL NO 10/729193
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884785 von Herrath
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Matthias G. von Herrath (Del Mar, California)
ABSTRACT The present invention provides compostions and methods for the prevention or treatment of autoimmune disorders. In particular, the invention methods utilize genetic material encoding at least a portion of an autoreactive epitope that, upon administration to a subject, acts to modulate the immune system thereby ameliorating conditions associated with an autoreactive antigen.
FILED Thursday, June 17, 1999
APPL NO 09/336672
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884809 Levi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Roberto Levi (New York, New York);  Randi B. Silver (New York, New York)
ABSTRACT The invention provides a method for reducing cardiac dysfunctions in a human. The method comprises administration to the human of an effective amount of a selective histamine H3 Receptor agonist. In one embodiment, the method comprises limiting the accumulation of intracellular sodium (Nai) by inhibiting the Na+/H+ exchanger activity in the human having a cardiac dysfunction, or a predisposition to a cardiac dysfunction. In another embodiment the method comprises inhibiting the N-type Ca2+ channel to modulate the concentration of intracellular calcium. The invention also provides a pharmaceutical composition that includes a selective histamine H3 Receptor agonist with a pharmaceutical carrier.
FILED Wednesday, February 13, 2002
APPL NO 10/076204
ART UNIT 1614 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884871 Luyten et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Frank P. Luyten (Rockville, Maryland);  Malcolm Moos, Jr. (Bethesda, Maryland);  Bang Hoang (University Heights, Ohio);  Shouwen Wang (Rockville, Maryland)
ABSTRACT An isolated cDNA encoding a growth-inducing protein, Frzb, capable of stimulating bone, cartilage, muscle and nerve tissue formation. The CDNA and protein sequences of human and bovine frzb are provided. Production and purification of recombinant Frzb are also described.
FILED Friday, December 07, 2001
APPL NO 10/014055
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884873 Bonner et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) William M. Bonner (Potomac, Maryland);  Emmy Rogakou (Bethesda, Maryland)
ABSTRACT The present invention provides an isolated or purified antibody or antigenically-reactive fragment thereof that specifically binds to a C-terminal phosphorylated serine in an H2A histone protein and a product comprising the same. The present invention further provides fusion proteins comprising the isolated or purified antibody or antigenically-reactive fragment thereof. Also provided by the present invention are a method and a kit for determining double-stranded breaks in DNA. The method comprises contacting a sample comprising H2A histone proteins with the isolated or purified antibody or antigenically-reactive fragment thereof and detecting binding of the antibody or fragment thereof to an H2A histone protein in the sample. The detection of the binding of the antibody or fragment thereof to the H2A histone protein indicates the presence of a DNA double-stranded break in DNA.
FILED Wednesday, November 07, 2001
APPL NO 10/045720
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885762 Saha et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Punam Kumar Saha (Philadelphia, Pennsylvania);  Jayaram K. Udupa (Audobon, Pennsylvania)
ABSTRACT The invention provides novel scale-based filtering methods that use local structure size or “object scale” information to arrest smoothing around fine structures and across even low-gradient boundaries. One method teaches a weighted average over a scale-dependent neighborhood; while another employs scale-dependent diffusion conductance to perform filtering. Both methods adaptively modify the degree of filtering at any image location depending on local object scale. This permits a restricted homogeneity parameter to be accurately used for filtering in regions with fine details and in the vicinity of boundaries, while at the same time, a generous filtering parameter is used in the interiors of homogeneous regions.
FILED Wednesday, February 07, 2001
APPL NO 09/779032
ART UNIT 2625 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/131
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 06883290 Dinwoodie
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) PowerLight Corporation (Berkeley, California)
INVENTOR(S) Thomas L. Dinwoodie (Piedmont, California)
ABSTRACT A barrier, such as a PV module, is secured to a base by a support to create a shingle assembly with a venting region defined between the barrier and base for temperature regulation. The bottom edges of the barriers of one row may overlap the top edges of the barriers of another row. The shingle assemblies may be mounted by first mounting the bases to an inclined surface; the barriers may be then secured to the bases using the supports to create rows of shingle assemblies defining venting regions between the barriers and the bases for temperature regulation.
FILED Wednesday, February 20, 2002
APPL NO 10/078913
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/748.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06883483 Knudsen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Dresser, Inc. (Addison, Texas)
INVENTOR(S) Julian R. Knudsen (North Prairie, Wisconsin);  Christopher B. Welch (Waukesha, Wisconsin)
ABSTRACT In an engine having a rocker member adapted to rock about an axis intermediate the rocker member and a pushrod extending from a lower body to an upper body and engaging an end of the rocker member, a gasket for sealing the lower body to the upper body is provided. The gasket includes a sealing portion adapted to substantially seal at least a portion of the upper body to the lower body, and a pushrod support portion extending outwardly from the sealing portion adapted to engage the pushrod. At least a portion of the pushrod support portion engaging the pushrod is constructed from a material that is softer than the material of the pushrod.
FILED Thursday, November 20, 2003
APPL NO 10/718431
ART UNIT 3748 — Printing/Measuring and Testing
CURRENT CPC
Internal-combustion engines
123/90.370
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884290 Swain et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Greg M. Swain (East Lansing, Michigan);  Jian Wang (Westmont, Illinois)
ABSTRACT An electrically conducting and dimensionally stable diamond (12, 14) and metal particle (13) electrode produced by electrodepositing the metal on the diamond is described. The electrode is particularly useful in harsh chemical environments and at high current densities and potentials. The electrode is particularly useful for generating hydrogen, and for reducing oxygen and oxidizing methanol in reactions which are of importance in fuel cells.
FILED Wednesday, January 08, 2003
APPL NO 10/338318
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/68
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884478 Alivisatos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) A. Paul Alivisatos (Oakland, California);  Liang-shi Li (Berkeley, California)
ABSTRACT Semiconductor liquid crystal compositions and methods for making such compositions are disclosed. One embodiment of the invention is directed to a liquid crystal composition including a solvent and semiconductor particles in the solvent. The solvent and the semiconductor particles are in an effective amount in the liquid crystal composition to form a liquid crystal phase.
FILED Wednesday, October 23, 2002
APPL NO 10/280135
ART UNIT 1756 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Stock material or miscellaneous articles
428/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884527 Groves et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Los Alamos, Minnesota)
INVENTOR(S) James R. Groves (Los Alamos, New Mexico);  Stephen R. Foltyn (Los Alamos, New Mexico);  Paul N. Arendt (Los Alamo, New Mexico)
ABSTRACT An article including a substrate, a layer of a metal phosphate material such as an aluminum phosphate material upon the surface of the substrate, and a layer of an oriented cubic oxide material having a rock-salt-like structure upon the metal phosphate material layer is provided together with additional layers such as a HTS top-layer of YBCO directly upon a layer of a buffer material such as a SrTixRu1−xO3 layer.
FILED Monday, July 21, 2003
APPL NO 10/624348
ART UNIT 1754 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Stock material or miscellaneous articles
428/701
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884624 Gourley
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Paul L. Gourley (Albuquerque, New Mexico)
ABSTRACT A method of detecting cancer using a laser biocavity having a semiconductor laser including a microchannel through which cells in fluid traverse, comprising determining the laser wavelength of the laser biocavity with only fluid in the microchannel; determining the wavelength shift of the biocavity when each cell passes through the microchannel; and determining the percentage of cells in G2 phase from the wavelength shift of the cells; wherein an increased percentage of G2 phase cells is an indication of cancer.
FILED Thursday, April 20, 2000
APPL NO 09/553978
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/63
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885008 Douglas et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Southeastern Univ. Research Assn. (Newport News, Virginia)
INVENTOR(S) David R. Douglas (Newport News, Virginia);  George R. Neil (Williamsburg, Virginia)
ABSTRACT A particle beam recirculated chicane geometry that, through the inducement of a pair of 180 degree bends directed by the poles of a pair of controllable magnetic fields allows for variation of dipole position, return loop radii and steering/focussing, thereby allowing the implementation of independent variation of path length and momentum compaction.
FILED Friday, March 07, 2003
APPL NO 10/383823
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/396.ML0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885025 Tung et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Universal Display Corporation (Ewing, New Jersey)
INVENTOR(S) Yeh-Jiun Tung (Princeton, New Jersey);  Michael Lu (Lawrenceville, New Jersey);  Raymond C. Kwong (Plainsboro, New Jersey)
ABSTRACT The present invention relates to organic light emitting devices (OLEDs). The devices of the present invention are efficient white or multicolored phosphorescent OLEDs which have a high color stability over a wide range of luminances. The devices of the present invention comprise an emissive region having at least two emissive layers, with each emissive layer comprising a different host and emissive dopant, wherein at least one of the emissive dopants emits by phosphorescence.
FILED Thursday, July 10, 2003
APPL NO 10/618160
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885192 Clarke et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) John Clarke (Berkeley, California);  Robert McDermott (Louisville, Colorado);  Alexander Pines (Berkeley, California);  Andreas Heinz Trabesinger (Zurich, Switzerland)
ABSTRACT Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned de superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.
FILED Thursday, February 06, 2003
APPL NO 10/360823
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/300
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 06883559 Jeon et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Noo Li Jeon (Irvine, California);  Stephan K. W. Dertinger (Munich, Germany);  Daniel T. Chiu (Seattle, Washington);  Insung S. Choi (Daejeon, South Korea);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A method and apparatus for treating a fluid. A method for treating a fluid may include combining two or more separate streams into a common stream and then splitting the common stream into a new set of separate streams wherein the separate streams may possess different properties. The separate streams may be combined to produce a gradient, such as a concentration gradient or shear gradient. The apparatus of the invention may provide a network of fluidic channels that may be used to manipulate a fluid to produce, for example, a gradient or a series of solutions containing a substance at varying concentrations.
FILED Tuesday, October 21, 2003
APPL NO 10/690475
ART UNIT 3751 — Fluid Handling and Dispensing
CURRENT CPC
Fluent material handling, with receiver or receiver coacting means
141/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884093 Baldo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Marc Baldo (Princeton, New Jersey);  Peter Peumans (Princeton, New Jersey);  Stephan Forrest (Princeton, New Jersey);  Changsoon Kim (Princeton, New Jersey)
ABSTRACT An organic semiconductor device is provided. The device has a first electrode and a second electrode, with an organic semiconductor layer disposed between the first and second electrodes. An electrically conductive grid is disposed within the organic semiconductor layer, which has openings in which the organic semiconductor layer is present. At least one insulating layer is disposed adjacent to the electrically conductive grid, preferably such that the electrically conductive grid is completely separated from the organic semiconductor layer by the insulating layer. Methods of fabricating the device, and the electrically conductive grid in particular, are also provided. In one method, openings are formed in an electrically conductive layer with a patterned die, which is then removed. In another method, an electrically conductive layer and a first insulating layer are etched through the mask to expose portions of a first electrode. In yet another method, a patterned die is pressed into a first organic semiconductor layer to create texture in the surface of the first organic semiconductor layer, and then removed. An electrically conductive material is then deposited onto the first organic semiconductor layer from an angle to form a grid having openings as a result of the textured surface and the angular deposition. In each of the methods, insulating layers are preferably deposited or otherwise formed during the process to completely separate the electrically conductive layer from previously and subsequently deposited organic semiconductor layers.
FILED Tuesday, September 17, 2002
APPL NO 10/246508
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Electrical connectors
439/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884613 Le Doux et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Joseph M. Le Doux (Decatur, Georgia);  Martin L. Yarmush (Newton, Massachusetts);  Jeffrey R. Morgan (Sharon, Massachusetts)
ABSTRACT The invention provides new methods for purifying and concentrating viruses. The inventors have discovered that high molecular weight proteoglycans present in retroviral stocks are co-concentrated with the retroviruses, and can inhibit retroviral transduction. The new purification and concentration methods feature treatment of virus stock with an anionic polyelectrolyte and a cationic polyelectrolyte, followed by centrifugation. The new methods minimize the amount of proteoglycan co-precipitated with the infectious virus.
FILED Friday, August 24, 2001
APPL NO 09/939065
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/239
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884859 Grubbs et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Robert H. Grubbs (South Pasadena, California);  Oren A. Scherman (Pasadena, California);  Hyunjin M. Kim (Pasadena, California)
ABSTRACT A method is provided for synthesizing a polymer in a controlled fashion using a ring-opening metathesis polymerization (ROMP) reaction, wherein polymerization is carried out using a catalytically effective amount of an olefin metathesis catalyst and a bridged bicyclic or polycyclic olefin monomer that contains at least two heteroatoms directly or indirectly linked to each other. Preferred catalysts are Group 8 transition metal complexes, particularly complexes of Ru and Os. Such complexes include the ruthenium bisphosphine complex (PCy3)2(Cl)2Ru═CHPh (1) and the ruthenium carbene complex (IMesH2)(PCy3)(Cl)2Ru═CHPh (2). The invention also provides novel regioregular polymers synthesized using the aforementioned methodology, wherein the polymers may be saturated, unsaturated, protected, and/or telechelic. An exemplary polymer is poly((vinyl alcohol)2-alt-methylene)(MVOH).
FILED Thursday, August 29, 2002
APPL NO 10/232105
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
526/135
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885686 Botez
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Dan Botez (Madison, Wisconsin)
ABSTRACT A semiconductor laser is formed on a semiconductor substrate with an array of laterally spaced laser device elements each including a second order distributed feedback grating bounded by distributed Bragg reflector gratings and a central phase shift in the distributed feedback grating. The device elements in which the distributed feedback grating and the distributed Bragg reflector gratings are formed have a lower effective index than the index of the interelement regions and are spaced so as to form an antiguided array. A two-dimensional semiconductor array laser may be formed of four or more of the semiconductor array devices arranged on the substrate to provide long range coherent coupling via traveling waves of light between the device elements.
FILED Thursday, January 16, 2003
APPL NO 10/345613
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/43
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885970 Petrovic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Vladan Petrovic (West Roxbury, Massachusetts);  Alex M. Stankovic (Boston, Massachusetts)
ABSTRACT A method and system for the sensorless estimation of the states of the mechanical subsystem of a motor are disclosed. In particular, the method and system split the estimation problem into two sub-problems: the estimation of motor parameters as a function of position, and the determination of the states of the mechanical subsystem of the motor using the estimated parameters via a state observer. Motor current and PWM voltage in a polyphase system is measured or otherwise determined and converted into current and voltage in α-β coordinates. A least square estimator is constructed that uses the voltage and current in α-β coordinates and provides an estimate of the motor parameters, and in particular, the inductances of the motor, which are a function of the rotor position. These estimated inductances are used to drive a state observer whose dynamics have been selected to provide as an output the state of the mechanical subsystem of the motor, and in particular, the position, velocity, and acceleration of this subsystem.
FILED Thursday, March 20, 2003
APPL NO 10/394504
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/169
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 06883330 Guinan et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Daniel P. Guinan (Hobe Sound, Florida);  Alan Drake (Tequesta, Florida);  Dean Andreadis (Palm Beach Gardens, Florida);  Stephen A. Beckel (Palm Beach Gardens, Florida)
ABSTRACT The present invention relates to an improved variable geometry inlet for a scram jet engine having at least one combustor module. The variable geometry inlet comprises each combustor module having two sidewalls. Each of the sidewalls has a central portion with a thickness and a tapered profile forward of the central portion. The tapered profile terminates in a sharp leading edge. The variable geometry inlet further comprises each module having a lower wall and a movable cowl flap positioned forward of the lower wall. The movable cowl flap has a leading edge and the leading edges of the sidewalls intersect the leading edge of the cowl flap.
FILED Wednesday, October 02, 2002
APPL NO 10/264172
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/768
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06883543 Tew et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) David E. Tew (New Britain, Connecticut);  Wendell V. Twelves, Jr. (Manchester, Connecticut)
ABSTRACT A pulse detonation engine (10) is provided with an aerovalve (14) for controlling the pressure of injected propellants (Ox, Fuel) in an open-ended detonation chamber (26). The propellants are injected at such pressure and velocity, and in a direction generally toward a forward thrust wall end (16) of the detonation chamber (26), an aerovalve (14) is formed which effectively inhibits or prevents egress of the propellant from the detonation chamber (26). A shock wave (34) formed by the injected propellant acts, after reflection by the thrust wall end (16) and in combination with the aerovalve (14), to compress and conserve, or increase, the pressure of the injected propellant. Carefully timed ignition (28) effects a detonation pulse under desired conditions of maintained, or increased, pressure. Termination of the propellant injection serves to “open” the aerovalve (14), and exhaust of the combusted propellants occurs to produce thrust. Alternate embodiments of propellant injection mechanisms (12, 112) provide pulse valves (24, 122, 124) each having a fixed slotted disk (40, 140, 240) and a rotating slotted disk (42, 142, 242) to provide the desired high speed valving of discrete pulses of propellant for injection.
FILED Wednesday, June 25, 2003
APPL NO 10/603845
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/624.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884028 Brauer et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) John Christopher Brauer (Lawrenceburg, Indiana);  Kenneth Martin Lewis (Mason, Ohio);  Fred Martin Heise (Cincinnati, Ohio)
ABSTRACT A blade retention assembly is provided that comprises: a disk, a plurality of blades, each having a dovetail disposed in one of an array of slots formed in the outer periphery of the disk, an annular inner retainer attached to the disk, and a plurality of arcuate blade retainers, the blade retainers being secured to the inner retainer by a hooked rabbet joint. A blade retainer is also provided, comprising an arcuate body having a planar inner face having an arcuate depression formed therein defining a sealing lip, and an aft face disposed opposite the inner face which has an arcuate rim formed therein.
FILED Monday, September 30, 2002
APPL NO 10/261072
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/173.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885564 Hockett
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) John E. Hockett (Glendale, Arizona)
ABSTRACT An electronics chassis box includes a pair of opposing sidewalls, a pair of opposing end walls, a bottom surface, a top cover, and ring connectors assemblies mounted in selective ones of the walls of the electronic box. Boss members extend from the bottom surface at different heights upon which circuit cards are mounted in spatial relationship to each other. A flex interconnect substantially reduces and generally eliminates the need of a motherboard by interconnecting the circuit cards to one another and to external connectors mounted within the ring connector assemblies.
FILED Tuesday, February 11, 2003
APPL NO 10/365036
ART UNIT 2841 — Optics
CURRENT CPC
Electricity: Electrical systems and devices
361/796
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885779 Keys et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Andrew S. Keys (Harvest, Alabama);  Richard L Fork (Madison, Alabama)
ABSTRACT An optical phase modulator includes a bandpass multilayer stack, formed by a plurality of dielectric layers, preferably of GaAs and AlAs, and having a transmission function related to the refractive index of the layers of the stack, for receiving an optical input signal to be phase modulated. A phase modulator device produces a nonmechanical change in the refractive index of each layer of the stack by, e.g., the injection of free carrier, to provide shifting of the transmission function so as to produce phase modulation of the optical input signal and to thereby produce a phase modulated output signal.
FILED Wednesday, June 06, 2001
APPL NO 09/877801
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/2
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 06884384 Merrill et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Siemens Westinghouse Power Corporation (Orlando, Florida)
INVENTOR(S) Gary Brian Merrill (Orlando, Florida);  Jay Edgar Lane (Murrysville, Pennsylvania);  Curtis Gosik (Irwin, Pennsylvania)
ABSTRACT A method for making a thermal insulating material includes the steps of: providing a chamber, placing hollow geometric shapes in the chamber, closing the chamber, evacuating air from the chamber, feeding a slurry into an adjacent slurry chamber, pressurizing the slurry chamber and forcing the slurry in to the sphere chamber around the spheres against a fibrous material adjacent a side wall of the sphere chamber. The fibrous material allows capillary wicking of the liquid from the slurry around the spheres. Due to this pressure the spheres and slurry are semi dried into a green state. The material in its green state green is subsequently dried and fired to form the insulating material.
FILED Thursday, September 27, 2001
APPL NO 09/965558
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/642
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06885757 Bloom et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Sarnoff Corporation (Princeton, New Jersey)
INVENTOR(S) Jeffrey Adam Bloom (West Windsor, New Jersey);  John Scott Nafziger (Morrisville, Pennsylvania)
ABSTRACT A low-frequency, temporally asymmetric watermark carrier decreases in luminance in a substantially monotonic manner more slowly than it increases in luminance in a substantially monotonic manner. This allows the carrier to be embedded, e.g., in a video work, in a manner that renders the resultant watermark virtually invisible to the human eye. Moreover, the resultant watermark is substantially resistant to common pirating techniques in which high-frequency visual content (e.g., including watermark data) tends to be filtered out by piracy processing.
FILED Monday, June 21, 2004
APPL NO 10/872921
ART UNIT 2623 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/100
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 06884551 Fritze et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Michael Fritze (Acton, Massachusetts);  Brian Tyrrell (Pawtucket, Rhode Island)
ABSTRACT A method forms patterns on a substrate by exposing the substrate a first time and exposing the substrate a second time using a mask containing gray-tone features. The gray-tone features locally adjust an exposure dose in regions corresponding to features defined in the primary exposure. Moreover, the gray-tone features enable the forming of features having different critical dimensions on a substrate. The gray-tone features may be sub-resolution features and formed by pixellation. The trim mask containing gray-tone features may have regions with different transmissivities.
FILED Wednesday, September 04, 2002
APPL NO 10/234783
ART UNIT 1756 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884982 Beusch
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) John U. Beusch (Stow, Massachusetts)
ABSTRACT An electronic imager includes a detector array, a plurality of processing circuits, each responsive to an output signal from a respective detector element of the array and to a determination that signal coupling in general or charge sharing in particular occurred. The imager further includes a shared channel circuit coupled to at least two processing circuits for receiving an output signal from the processing circuits in response to a determination that signal coupling has occurred and for generating an output signal in response to the received signals. The shared channel circuit further directs the output signal to an image sub-pixel, wherein a plurality of sub-pixels are associated with each radiation sensitive element.
FILED Tuesday, February 19, 2002
APPL NO 10/078231
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 06884921 Browse et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Washington State University Research Foundation (Pullman, Washington)
INVENTOR(S) John A. Browse (Palouse, Washington);  James P. Spychalla (Antigo, Wisconsin)
ABSTRACT Recombinant expression of fat-1 gene of Caenorhabditis elegans in a wide variety of cells, including cells of Arabidopsis thaliana and Saccharomyces cerevisiae, produces a polypeptide having ω-3 desaturase activity.
FILED Thursday, March 21, 2002
APPL NO 10/104339
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/281
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 06883290 Dinwoodie
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) PowerLight Corporation (Berkeley, California)
INVENTOR(S) Thomas L. Dinwoodie (Piedmont, California)
ABSTRACT A barrier, such as a PV module, is secured to a base by a support to create a shingle assembly with a venting region defined between the barrier and base for temperature regulation. The bottom edges of the barriers of one row may overlap the top edges of the barriers of another row. The shingle assemblies may be mounted by first mounting the bases to an inclined surface; the barriers may be then secured to the bases using the supports to create rows of shingle assemblies defining venting regions between the barriers and the bases for temperature regulation.
FILED Wednesday, February 20, 2002
APPL NO 10/078913
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/748.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 06884606 Sinskey et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Anthony J. Sinskey (Boston, Massachusetts);  Philip A. Lessard (Framingham, Massachusetts);  Laura B. Willis (Cambridge, Massachusetts)
ABSTRACT The present invention concerns an anaplerotic enzyme from Corynebacterium glutamicum which replenishes oxaloacetate consumed during lysine and glutamic acid production in industrial fermentations. In particular, isolated nucleic acid molecules are provided encoding the pyruvate carboxylase protein. Pyruvate carboxylase polypeptides are also provided.
FILED Tuesday, January 15, 2002
APPL NO 10/045072
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 06884842 Soane et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Alnis BioSciences, Inc. (Emeryville, California)
INVENTOR(S) David S. Soane (Piedmont, California);  Stephen E. Barry (Oakland, California);  Andrew Goodwin (Oakland, California);  David A. Offord (Castro Valley, California);  Michael G. Perrott (San Francisco, California)
ABSTRACT Synthetic polymer complements (SPCs) are provided, as well as methods for their synthesis and use. The SPCs may have surfaces that include functional groups that are complementary to surface sites of targets such as nanostructures or macromolecular targets, and may be capable of specifically interacting with such targets. The positions of the functional groups in one embodiment are stabilized by a polymer network. The SPCs are formed by contacting the target with a set of monomers which self-assemble on the target, and then are polymerized into a network to form the synthetic polymer complement. At least a portion of the surface of the resulting SPC thus may include an imprint of the target. The complex of the SPC and the target may be the desired product. Alternatively, the target is released, for example, by controllably expanding and contracting the crosslinked network. The SPC is isolated and used in many applications.
FILED Friday, October 26, 2001
APPL NO 10/055837
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
525/54.100
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 26, 2005.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050426.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital