FedInvent™ Patents
Patent Details for Tuesday, July 12, 2005
This page was updated on Sunday, March 26, 2023 at 07:47 PM GMT
Department of Health and Human Services (HHS)
| US 06915701 | Tarler |
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| ASSIGNEE(S) | Cleveland Medical Devices Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Matthew David Tarler (Westlake, Ohio) |
| ABSTRACT | The present invention is related to a composite sheet material, a method of producing this material, and the application of this material as a sensor for monitoring and measuring shear forces (or lateral translation). In one embodiment, the present invention includes a composite sheet material having an upper and a lower surface comprising an elastomeric matrix, which is essentially non-conductive, and discrete electrically conductive elements within the matrix wherein the electrically conductive elements in a region of the composite sheet material are arranged into columns, and the orientation of these columns are in an essentially organized, non-random pattern with a majority of these columns oriented at angles less than about 90° and greater than about 15° to the lower surface of the composite sheet material. In another embodiment, the present invention provides for a method of forming the sensors. |
| FILED | Friday, July 18, 2003 |
| APPL NO | 10/622616 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/774 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916419 | Prusiner et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stanley B. Prusiner (San Francisco, California); Jiri G. Safar (Walnut Creek, California) |
| ABSTRACT | Devices such as flow through columns, substrates such as spherical polymer beads, and methods of using such to remove prions from any liquid sample are disclosed. A surface of a substrate is coated with a prion complexing agent, such as a salt of phosphotungstic acid. Blood or plasma passing through a column containing beads coated with prion complexing agent are rendered prion free. |
| FILED | Friday, March 21, 2003 |
| APPL NO | 10/394555 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916462 | Contag et al. |
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| ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Portola Valley, California) |
| ABSTRACT | Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen. |
| FILED | Monday, December 16, 2002 |
| APPL NO | 10/319588 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916471 | Stamler et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Jonathan S. Stamler (Chapel Hill, North Carolina); Joseph Bonaventura (Beaufort, North Carolina); John R. Pawloski (Raleigh, North Carolina); Timothy J. McMahon (Durham, North Carolina) |
| ABSTRACT | Red blood cells can be loaded with low molecular weight nitrosylating agents, such as S-nitrosothiols, to act as a delivery system for NO+ groups to tissues. Loaded red blood cells can be used in methods of therapy for conditions which are characterized by abnormal O2 metabolism of tissues, oxygen-related toxicity, abnormal vascular tone, abnormal red blood cell adhesion, or abnormal O2 delivery by red blood cells. Such treatment of red blood cells can be extended to in vivo therapies, with the object to achieve an increase in the ratio of red blood cell S-nitrosothiol to hemoglobin. |
| FILED | Tuesday, October 23, 2001 |
| APPL NO | 10/045603 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.730 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916475 | Müller et al. |
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| ASSIGNEE(S) | HEMA Diagnostic Systems L.L.C. (Miami Beach, Florida) |
| INVENTOR(S) | Sybille Müller (Lexington, Kentucky); Haitao Wang (Lexington, Kentucky) |
| ABSTRACT | The present invention provides an anti-idiotypic antibody having specific reactivity with an idiotope common to more than one type of anti-HIV-1 antibody, and having no specific reactivity with non-HIV-1 antibodies. The present invention provides methods of diagnosis, monitoring and treatment of HIV-related diseases through the use of this antibody or related compounds. |
| FILED | Tuesday, October 15, 2002 |
| APPL NO | 10/271672 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/131.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916490 | Garver et al. |
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| ASSIGNEE(S) | UAB Research Center (, None); The Johns Hopkins University (, None) |
| INVENTOR(S) | Robert I. Garver (Hoover, Alabama); Subramanian Kalyanasundaram (Gaithersburg, Maryland); Kam W. Leong (Ellicott City, Maryland) |
| ABSTRACT | The present invention contemplates in part coacervates in which a bioactive substance and delivery agent are encapsulated therein for controlled release. In certain embodiments, said bioactive substance and delivery agent are a viral vector and virus, respectively. Processes for preparing and using coacervates of the present invention are described. |
| FILED | Friday, July 23, 1999 |
| APPL NO | 09/359593 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916604 | Eyre |
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| ASSIGNEE(S) | Washington Research Foundation (Seattle, Washington) |
| INVENTOR(S) | David R. Eyre (Mercer Island, Washington) |
| ABSTRACT | Peptides synthesized to match the human α1 (I) and α2 (I) amino-telopeptide sequences of type I collagen degradation products in body fluids, preferably either Asp-GIu-Lys-Ser-Thr-Gly-Gly (SEQ ID NO:5) or Gln-Tyr-Asp-Gly-Lys-Gly-Val-Gly (SEQ ID NO:6). used as calibrators and antigens in immunoassays for detecting type I collagen degradation products in body fluids. |
| FILED | Friday, March 07, 2003 |
| APPL NO | 10/384894 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916611 | Goncz et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kaarin Kerr Goncz (St. Albans, Vermont); Dieter Cotter Gruenert (Shelburne, Vermont); Alessia Colosimo (Rome, Italy) |
| ABSTRACT | An expression vector system comprising a pair of expression vectors constructed from a wild-type and a mutant version of a maker, reporter or selection gene, and a method for optimization and confirmation of DNA delivery and of gene targeting and for quantification of targeting frequency. Novel prokaryotic/eukaryotic DNA vectors used for DNA delivery and gene targeting assessment and targeting frequency quantification. |
| FILED | Monday, February 26, 2001 |
| APPL NO | 09/794689 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916627 | Kastan et al. |
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| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Michael B. Kastan (Cordova, Tennessee); Christopher Bakkenist (Cordova, Tennessee) |
| ABSTRACT | The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided. |
| FILED | Friday, January 24, 2003 |
| APPL NO | 10/351733 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916654 | Sims et al. |
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| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Peter J. Sims (Mequon, Wisconsin); Alfred L. M. Bothwell (Guilford, Connecticut); Eileen A. Elliot (New Haven, Connecticut); Richard A. Flavell (Killingworth, Connecticut); Joseph Madri (North Branford, Connecticut); Scott Rollins (Monroe, Connecticut); Leonard Bell (Woodbridge, Connecticut); Stephen Squinto (Irvington, New York) |
| ABSTRACT | Genetically engineered cells are provided which can serve as universal donor cells in such applications as reconstruction of vascular linings or the administration of therapeutic agents. The cells include a coding region which provides protection against complement-based lysis, i.e., hyperacute rejection. In addition, the cell's natural genome is changed so that functional proteins encoded by either the class II or both the class I and the class II major histocompatibility complex genes do not appear on the cell's surface. In this way, attack by T-cells is avoided. Optionally, the cells can include a self-destruction mechanism so that they can be removed from the host when no longer needed. |
| FILED | Friday, May 05, 2000 |
| APPL NO | 09/566254 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916660 | Wang et al. |
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| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Binghe Wang (Apex, North Carolina); Brent Weston (Durham, North Carolina); Wenqian Yang (Raleigh, North Carolina) |
| ABSTRACT | Fluorescent sensor compounds having the formula: wherein L is selected from the group consisting of alkyl, alkylene, aryl, cycloalkyl, alkoxy, aryloxy, arylalkyl, and arylalkyloxyl; each m, m′, n, n′, p, and p′ is independently an integer from 0 to 4, inclusive; and each R1, R′1, R2, R′2, R3 and R′3 is independently selected from the group consisting of hydrogen, alkyl, alkylene, aryl, cycloalkyl, alkoxy, aryloxy, arylalkyl, arylalkyloxyl, halo, substituted and unsubstituted amino, and substituted and unsubstituted thiol, are useful for the selective detection of saccharides such as glucose and sialyl Lewis X. The compounds find particular use in detecting saccharides in biological samples, and in detecting cancer cells that express cell surface polysaccharides such as sialyl Lewis X. |
| FILED | Tuesday, May 13, 2003 |
| APPL NO | 10/437362 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916801 | Buynak et al. |
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| ASSIGNEE(S) | Alamx, LLC (Tucson, Arizona) |
| INVENTOR(S) | John D. Buynak (Dallas, Texas); Lakshminarayana Vogeti (Dallas, Texas) |
| ABSTRACT | The invention provides compounds of formula (I): wherein: R1-R4 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β-lactamase enzymes, for enhancing the activity of β-lactam antibiotics, and for treating β-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula (I), wherein R1 and R2 are each independently hydrogen, (C1-C10)alkyl, (C2-C10)alkenyl, (C2-C10)alkenyl, (C3-C8)cycloalkyl, (C1-C10)alkoxy, (C1-C10)alkanoyl, (C1-C10)alkanoyloxy, (C1-C10)alkoxycarbonyl, aryl, heterocycle, halo, cyano, nitro, —COORe, —C(═O)NRfRg, —OC(═O)NRfRg, NRfRg, or —S(O)nRh; R3 is hydrogen, halo, aryl, heteroaryl, —S(O)nRh, or —CH═CHC(═O)NRmRp; R4 is hydrogen; A is thio, sulfinyl, or sulfonyl; and intermediates useful for the synthesis of compounds of formula (I). |
| FILED | Wednesday, July 24, 2002 |
| APPL NO | 10/202405 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916802 | Shayman et al. |
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| ASSIGNEE(S) | Genzyme Corporation (Cambridge, Massachusetts); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | James A. Shayman (Ann Arbor, Michigan); David J. Harris (Lexington, Massachusetts); Craig Siegel (Woburn, Massachusetts); Carol A. Nelson (Westford, Massachusetts); Diane P. Copeland (North Billerica, Massachusetts) |
| ABSTRACT | The present invention provides amino ceramide-like compounds which inhibit glucosyl ceramide (GlyCer) formation by inhibiting the enzyme GlyCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer synthase inhibition activity and are therefore useful in therapeutic methods for treating various conditions and diseases associated with altered glycosphingolipid levels. |
| FILED | Wednesday, May 05, 2004 |
| APPL NO | 10/839497 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/210.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916823 | Mailman et al. |
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| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Richard B. Mailman (Chapel Hill, North Carolina); David E. Nichols (West Lafayette, Indiana); Xuemei Huang (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention relates to the treatment of dopamine-related dysfunction using full D1 dopamine receptor agonists in an intermittent dosing protocol with a short, but essential, “off-period.” The D1 agonist concentration is reduced during the “off-period” to obtain a plasma concentration of agonist that suboptimally activates D1 dopamine receptors for a period of time to prevent induction of tolerance. Specifically, the method comprises the steps of periodically administering to a patient a full D1 agonist with a half-life of up to about 6 hours at a dose resulting in a first plasma concentration of agonist capable of activating D1 dopamine receptors to produce a therapeutic effect. The dose is reduced at least once every 24 hours to obtain a second lower plasma concentration of agonist that results in suboptimal activation of D1 dopamine receptors for a period of time sufficient to prevent induction of tolerance. |
| FILED | Wednesday, January 16, 2002 |
| APPL NO | 10/050289 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916831 | Lee et al. |
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| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Kuo-Hsiung Lee (Chapel Hill, North Carolina); Yi Xia (Foster City, California); Zheng-Yu Yang (Foster City, California); Kenneth F. Bastow (Chapel Hill, North Carolina); Sheng-Chu Kuo (Tai Chung, Taiwan) |
| ABSTRACT | Compounds are described having a structure according to Formula I or Formula II: wherein: X is selected from the group consisting of O, NH, and S; Y is selected from the group consisting of O and S; m is from 1 to 3; n is from 1 to 5; R1 and R3 are each independently selected from the group consisting of H, hydroxy, lower alky, lower alkoxy, halo, amino, aminoalkyl, nitro, heteroaryl, —OC(═O)R6, —O(C═O)OR6; and —O(C═O)N(R6)2; and R2 is side chain such as an acetic acid side chain, where p is O to 4, R5 is hydroxy, alkoxy or amino, and R6 is H or lower alkyl, or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of cancer. |
| FILED | Monday, February 24, 2003 |
| APPL NO | 10/373399 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916832 | Nichols et al. |
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| ASSIGNEE(S) | University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | David E. Nichols (West Lafayette, Indiana); Russell A. Grubbs (Lafayette, Indiana); Richard B. Mailman (Chapel Hill, North Carolina) |
| ABSTRACT | Novel dopamine receptor ligands of the formula: pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction of the central or peripheral nervous system, are described. The compounds are expected to be useful in treating Parkinson's disease, improving cognition, improving memory, improving the negative symptoms of schizophrenia, improving attention-deficit hyperactivity disorder and related developmental disorders, treating substance abuse disorders, and in treating various peripheral conditions where changes in dopamine receptor occupation affects physiological function, including organ perfusion, cardiovascular function, and selected endocrine and immune system functions. |
| FILED | Tuesday, July 02, 2002 |
| APPL NO | 10/188579 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/321 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916843 | Liao et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | James K. Liao (Weston, Massachusetts); Darryl Zeldin (Chapel Hill, North Carolina) |
| ABSTRACT | Epoxyeicosatrienoic acids (EETs) are products of cytocrome P450 epoxygenases that have vasodilatory properties similar to endotheilum-derived hyperpolarizing factor (EDHF). The cytochrome P450 isoform CYP2J2 was cloned and identified as a source of EETs in human endothelial cells. Physiological concentrations of EETs or overexpression of CYP2J2 decreased cytolcine-induced endothelial cell adhesion molecule expression and prevented subsequent leukocyte adhesion to the vascular wall by a mechanism involving inhibition of transcription factor NF-κB and IκB kinase (IKK). The inhibitory effects of EETs were independent of their membrane hyporpolarizing effects suggesting that these molecules play an important non-vasodilatory role in vascular inflammation. |
| FILED | Wednesday, August 09, 2000 |
| APPL NO | 09/634369 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/449 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916903 | Eyre |
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| ASSIGNEE(S) | Washington Research Foundation (Seattle, Washington) |
| INVENTOR(S) | David R. Eyre (Seattle, Washington) |
| ABSTRACT | Peptides synthesized to match C-telopeptide components of type III collagen degradation products in body fluids, selected from among EKAGGF (SEQ ID NO:39), IGGEKAGG (SEQ ID NO:40), IGGEKAGGF (SEQ ID NO:41), IAGIGGEKAGG (SEQ ID NO:42), IAGIGGEKAGGF (SEQ ID NO:43), and EKAGG (SEQ ID NO:44) are useful as immunogens and antigens in collagen resorption assays. |
| FILED | Tuesday, July 08, 2003 |
| APPL NO | 10/615959 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916905 | Lazarus et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Lawrence H. Lazarus (Durham, North Carolina); Severo Salvadori (Ferrara, Italy) |
| ABSTRACT | A compound of formula: wherein X is a spacer comprising one or more amino acid residues and Y comprises an aromatic group and related compositions and methods of use. |
| FILED | Friday, December 21, 2001 |
| APPL NO | 10/037358 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/331 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916915 | Freedman et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Jonathan H. Freedman (Rougemont, North Carolina); Vivian H. C. Liao (Durham, North Carolina) |
| ABSTRACT | The present invention relates, in general, to stressor-responsive genes and, in particular, to metal-responsive genes, to mRNAs, to proteins encoded therein and to uses thereof, for example, as biomonitors and in drug discovery. |
| FILED | Wednesday, November 10, 1999 |
| APPL NO | 09/437450 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916917 | Baltimore et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David Baltimore (Pasadena, California); Xiaolu Yang (Philadelphia, Pennsylvania); Howard Y. Chang (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to a chimeric pro-caspase, which contains a pro-caspase domain and an oligomerizing domain. The invention also relates to an antibody that reacts specifically with a chimeric pro-caspase. In addition, the invention further relates to a polynucleotide encoding a chimeric pro-caspase, and to nucleotide sequences, which can hybridize specifically with a polynucleotide encoding a chimeric pro-caspase. The present invention also relates to a method of inducing apoptosis in a cell by providing a chimeric pro-caspase in the cell, wherein the chimeric pro-caspase includes a pro-caspase domain and an oligomerizing domain, whereby the chimeric pro-caspase forms an oligomer in the cell, thereby activating caspase activity of the chimeric pro-caspase and inducing apoptosis in the cell. The present invention further relates to a method of reducing the severity of a pathologic condition in a subject, by providing cells of the subject that are involved in the pathologic condition with a chimeric pro-caspase comprising a pro-caspase domain and an oligomerizing domain, whereby the chimeric pro-caspase forms an oligomer in the cells, thereby activating caspase activity of the chimeric pro-caspase, inducing apoptosis in the cells, and reducing the severity of the pathologic condition in the subject. |
| FILED | Wednesday, November 17, 1999 |
| APPL NO | 09/441926 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917726 | Levene et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Michael J. Levene (Ithaca, New York); Jonas Korlach (Ithaca, New York); Stephen W. Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Watt W. Webb (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/259268 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917883 | Ruddle et al. |
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| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Frank H. Ruddle (New Haven, Connecticut); Kenta Sumiyama (New Haven, Connecticut); Chang-Bae Kim (New Haven, Connecticut) |
| ABSTRACT | A method is described for efficiently searching non-coding DNA for known control elements. Short conserved DNA sequences can be identified among 3 or more species by selecting DNA sequences from species having a total genetic distance larger than one substitution per site at a neutrally evolving region and calculating the total substitutions using pair-wise genetic distances, with the pairs for comparison selected based on phylogenetic relationships. |
| FILED | Wednesday, January 15, 2003 |
| APPL NO | 10/345080 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 06915861 | Goodworth et al. |
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| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Allen R. Goodworth (Milford, Connecticut); William E. Lindsay (Mesa, Arizona); Daniel D. Wilke (Mesa, Arizona) |
| ABSTRACT | The present invention presents a system for packaging fire suppressing material. An outer membrane is configured to support and release a fire suppression material when impacted by a ballistic or incendiary round. An inner membrane is configured to support and release the fire suppression material when impacted by a ballistic or incendiary round, and the inner membrane and the outer membrane is connected to form at least one cell holding the fire suppression material. In accordance with other aspects of the invention, the inner and outer membranes suitably form a bubble pack filled with a fire suppression powder. Further, the inner and outer membranes may be combined with a lightweight honeycomb panel to form a lightweight and simple system to support fuel tanks. |
| FILED | Wednesday, September 18, 2002 |
| APPL NO | 10/246949 |
| ART UNIT | 3728 — Printing/Measuring and Testing |
| CURRENT CPC | Fire extinguishers 169/66 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916029 | Warner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Joseph G. Warner (Sterling Heights, Michigan) |
| ABSTRACT | A trailer axle has steerable wheels that rotate on hub assemblies pivotally mounted to the axle. Connected to the axle is a mechanism for controlling the pivoting of the hub assemblies and thereby limiting the extent to which the steerable wheels turn. The mechanism has a rod disposed along the axle and pivotally connected to the hub assemblies. A bracket on the axle has an aperture through which the rod passes, the aperture permitting the rod's motion both parallel to the axle and transverse to the axle. Flanges on the rod span an opening of the aperture and slidingly engage the bracket. The flanges are translatable on the bracket transversely to the axle but are immobile in a direction parallel to the axle. The mechanism has collars at the ends of the rod and two elongate coil springs encircling the rod. One end of each spring is affixed to the collar and the other end of each spring is affixed to the flange. The springs bias the rod and hub assemblies toward a position where the hub assemblies and wheels are oriented at a desired steering angle. The position of the collars on the rod can be adjusted to vary the bias of the spring. Adjusting the collars' positions also controls the distance between the springs' coils and thereby ultimately controls the degree of steering of the wheels. |
| FILED | Monday, March 24, 2003 |
| APPL NO | 10/400084 |
| ART UNIT | 3616 — Printing/Measuring and Testing |
| CURRENT CPC | Land vehicles 280/89.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916389 | Pesiri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nanotechnologies, Inc. (Austin, Texas) |
| INVENTOR(S) | David Richard Pesiri (Laguna Beach, California); Robert C. Dye (White Rock, New Mexico) |
| ABSTRACT | A process for producing a mixture of particulates using compressed gas and sonication. The process is particularly useful to mix reactive particulates, such as thermites. |
| FILED | Tuesday, August 13, 2002 |
| APPL NO | 10/217852 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive and thermic compositions or charges 149/109.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916446 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Laurence G. Miller (El Granada, California); Ronald S. Oremland (Brisbane, California); Shaun M. Baesman (San Mateo, California) |
| ABSTRACT | Methyl halide contaminants are oxidized in a reaction chamber containing a methylotrophic bacterium through direct oxidation of the methyl halide contaminant. Methyl halides may be used as a disinfectant, with the remnant methyl halide contaminant oxidized through direct oxidation by the methylotrophic bacterium. |
| FILED | Wednesday, September 18, 2002 |
| APPL NO | 10/251697 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916462 | Contag et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Portola Valley, California) |
| ABSTRACT | Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen. |
| FILED | Monday, December 16, 2002 |
| APPL NO | 10/319588 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916474 | Harvey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Barrett R. Harvey (Austin, Texas); George Georgiou (Austin, Texas); Brent L. Iverson (Austin, Texas) |
| ABSTRACT | The invention overcomes the deficiencies of the prior art by providing antibody compositions having improved affinities for Bacillus anthracis antigens. The compositions have important thereapeutic and diagnostic applications, including treatment or detection of infection by Bacillus anthracis. |
| FILED | Tuesday, July 15, 2003 |
| APPL NO | 10/620049 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916561 | Spitsberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Irene Spitsberg (Loveland, Ohio); Brett Allen Boutwell (Liberty Township, Ohio) |
| ABSTRACT | A reduced thermal conductivity thermal barrier coating having improved impact and erosion resistance for an underlying metal substrate of articles that operate at, or are exposed to, high temperatures. This coating comprises a zirconia-containing ceramic composition having a c/a ratio in the range of from about 1.0057 to about 1.0123 and stabilized in the tetragonal phase by a stabilizing amount of a stabilizing metal oxide. The coating has a fraction of porosity of from about 0.15 to about 0.25, and an impact and erosion resistance property defined by at least one of the following formulas: (a) I=exp. [5.85−(144×s)−(3.68×p)]; and/or; (b) E=[187−(261×p)−(9989×s)], wherein s=1.0117−c/a ratio; p is the fraction of porosity; I is least about 70 g/mil; and E is least about 80 g/mil. This coating can be used to provide a thermally protected article having a metal substrate and optionally a bond coat layer adjacent to and overlaying the metal substrate. The thermal barrier coating can be prepared by depositing the zirconia-containing ceramic composition on the bond coat layer, or the metal substrate in the absence of the bond coat layer. |
| FILED | Tuesday, December 30, 2003 |
| APPL NO | 10/748518 |
| ART UNIT | 1775 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Stock material or miscellaneous articles 428/701 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916585 | Sreenivasan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas Systems (Austin, Texas) |
| INVENTOR(S) | Sidlgata V. Sreenivasan (Austin, Texas); Byung J. Choi (Round Rock, Texas); Matthew Colburn (Austin, Texas); Todd Bailey (Austin, Texas) |
| ABSTRACT | A method of determining and correcting alignment during imprint lithography process is described. During an imprint lithographic process the template may be aligned with the substrate by the use of alignment marks disposed on both the template and substrate. The alignment may be determined and corrected for before the layer is processed. |
| FILED | Tuesday, May 27, 2003 |
| APPL NO | 10/446192 |
| ART UNIT | 1756 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916665 | Bayley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Hagan P. Bayley (College Station, Texas); Stefan G. Howorka (College Station, Texas); Liviu Movileanu (Bryan, Texas) |
| ABSTRACT | Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample. |
| FILED | Monday, February 12, 2001 |
| APPL NO | 09/781697 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916727 | Leitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher W. Leitz (Nashua, New Hampshire); Minjoo L. Lee (Cambridge, Massachusetts); Eugene A. Fitzgerald (Windham, New Hampshire) |
| ABSTRACT | A structure includes a tensile strained layer disposed over a substrate, the tensile strained layer having a first thickness. A compressed layer is disposed between the tensile strained layer and the substrate, the compressed layer having a second thickness. The first and second thicknesses are selected to define a first carrier mobility in the tensile strained layer and a second carrier mobility in the compressed layer. |
| FILED | Friday, June 21, 2002 |
| APPL NO | 10/177571 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916816 | Monaghan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska); The University of Bristol (Bristol, United Kingdom) |
| INVENTOR(S) | Daniel T. Monaghan (Omaha, Nebraska); David E. Jane (Bristol, United Kingdom); Heong Wai Tse (Bristol, United Kingdom) |
| ABSTRACT | Disclosed are compounds of formula (I) wherein: L is (a) optionally substituted by replacement of one or more of the hydrogen atoms on the phenanthrene ring system by one or more groups other than hydrogen; A is CH2, SO2 or C═O; X is CO2H, PO3H2, PO2H2, PO2HR5, PO2HOR5, SO3H, SO2H, or tetrazole; and R1, R2, R3, R4 and R5 are independently selected from H, alkyl, alkenyl, alkynyl, aryl and aralkyl; or a pharmaceutically acceptable acid salt or base addition salt or an in vivo hydrolysable ester or amide thereof. Compounds of formula (I) are selective NMDA receptor modulating agents and, therefore, may be used to advantage in vitro in neuroassays and in vivo in the treatment of disorders of the CNS |
| FILED | Monday, December 18, 2000 |
| APPL NO | 10/149847 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/252.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916902 | Inbasekaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dow Global Technologies Inc. (Midland, Michigan) |
| INVENTOR(S) | Michael Inbasekaran (Midland, Michigan); Yang Cheng (Saginaw, Michigan); Scott Gaynor (Midland, Michigan); Michelle L. Hudack (Grand Blanc, Michigan); Chun Wang (Midland, Michigan); Dean M. Welsh (Midland, Michigan); Weishi Wu (Midland, Michigan) |
| ABSTRACT | A composition comprising a polymer comprising a repeat unit of Formula I: wherein R1 is independently in each occurrence H, C1-40 hydrocarbyl or C3-40 hydrocarbyl containing one or more S, N, O, P or Si atoms, or both of R1 together with the 9-carbon on the fluorene, may form a C5-20 ring structure which may contain one or more S, N, or O atoms; R2 is independently in each occurrence C1-20 hydrocarbyl, C1-20 hydrocarbyloxy, C1-20 thioether, C1-20 hydrocarbyloxycarbonyl, C1-20 hydrocarbylcarbonyloxy, or cyano; a is independently in each occurrence, 0 or 1; X is O, S, SO2, C(R3)2 or N—R3 wherein R3 is aryl or substituted aryl of C6 to C40, aralkyl of C6 to C24, or alkyl of C1 to C24. Preferably R3 is aryl of C6 to C24 and more preferably R3 is an alkylated aryl group of C6 to C24; Ar is an aryl or heteroaryl group of C6 to C40 or substituted aryl or heteroaryl group of C6 to C40, preferably C6-C24, and most preferably C6-C4. Y is a conjugated moiety that can vary in each occurrence of the repeat unit. |
| FILED | Thursday, December 19, 2002 |
| APPL NO | 10/324270 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 528/397 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917138 | Nguyen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Clark T. -C. Nguyen (Ann Arbor, Michigan) |
| ABSTRACT | Several MEMS-based methods and architectures which utilize vibrating micromechanical resonators in circuits to implement filtering, mixing, frequency reference and amplifying functions are provided. A method and subsystem are provided for processing RF signals utilizing a plurality of vibrating micromechanical devices typically in the form of an IF mixer-filter and an RF channel selector or an image-reject RF filter. One of the primary benefits of the use of such architectures is a savings in power consumption by trading power for high selectivity (i.e., high Q). Also, such methods and circuits can eliminate the need for a low noise amplifier in a receiver or transceiver subsystem. Consequently, the present invention relies on the use of a large number of micromechanical links in SSI networks to implement signal processing functions with basically zero DC power consumption. |
| FILED | Thursday, July 24, 2003 |
| APPL NO | 10/625993 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917198 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark B. Johnson (Springfield, Virginia); Michael Miller (Alexandria, Virginia); Brian Bennett (Arlington, Virginia) |
| ABSTRACT | A modified hybrid Hall effect device is provided which is the combination of a conventional Hall effect device and a second Hall effect device having a Hall plate coupled to a ferromagnetic layer. The hybrid Hall effect device can be used to determine the independent magnetic field vector components comprising a vector magnetic field, such as for determining the {circumflex over (x)} and the {circumflex over (z)} components of a magnetic field, or for measuring the total magnitude of a vector magnetic field of any orientation. The modified Hall Effect device can be adapted for use as a magnetic field sensor for the detection of macroscopic objects that have associated magnetic fields, or for microscopic objects that have been tagged by microscopic magnetic particles. In one specific form, a plurality of hybrid Hall devices are electrically connected together to form an array in which a plurality of rows of hybrid Hall devices are electrically coupled to each other along a current axis, and the array is used for the detection of microscopic objects. |
| FILED | Friday, May 21, 2004 |
| APPL NO | 10/857368 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917343 | Sanchez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Titan Aerospace Electronics Division (Greenbelt, Maryland) |
| INVENTOR(S) | Victor C. Sanchez (Laurel, Maryland); William E. McKinzie, III (Fulton, Maryland); Rodolfo E. Diaz (Phoenix, Arizona) |
| ABSTRACT | A low profile antenna system includes an artificial magnetic conductor comprising a frequency selective surface (FSS) having an effective sheet capacitance which is electronically variable to control resonant frequency of the AMC and the resonant frequency of an antenna element positioned adjacent to the FSS. |
| FILED | Tuesday, September 17, 2002 |
| APPL NO | 10/246198 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/795 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917974 | Stytz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Martin R. Stytz (Beavercreek, Ohio); Sheila B. Banks (Orlando, Florida) |
| ABSTRACT | A system and method for generating and transmitting false packets along with a true packet to thereby hide or obscure the actual message traffic. A new extension header having a plurality of fields is positioned in the hierarchy of Internet protocol headers that control passage of the false packets and the true packet through the network. A sending host computer generates a plurality of false packets for each true packet and transmits the false packets and the true packet containing the Internet protocol headers and the extension header over the network. The new extension header is decrypted and re-encrypted each host that handles a message packet that uses the new extension header to control the random re-encryption of the true packet body at random hosts and the random generation of false packets at each host visited by a true packet, at the recipient of the true packet, and at any hosts that receive a false packet. |
| FILED | Thursday, January 03, 2002 |
| APPL NO | 10/039575 |
| ART UNIT | 2145 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/225 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917985 | Madruga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ewerton L. Madruga (Santa Cruz, California); Joaquin J. Garcia-Luna-Aceves (San Mateo, California) |
| ABSTRACT | A method of providing multicast routing for use in ad hoc broadcast networks, such as wireless and mobile networks. The method is described within a protocol referred to as core-assisted mesh protocol, or CAMP. The method departs from traditional tree-structured multicast protocols and utilizes multicast meshes in which the network need not be flooded with control or data packets to establish routing paths. Each router configured for CAMP is capable of accepting unique packets arriving from any neighbor in the mesh, wherein packets are forwarded along reverse shortest paths to the receiver. Multiple cores may be defined for a group wherein the loss of a single core does not prevent packet flow. Routers for sender-only hosts are allowed to join the multicast mesh in simplex mode, and in certain cases may join without the sending of a join request. |
| FILED | Friday, March 09, 2001 |
| APPL NO | 09/802476 |
| ART UNIT | 2155 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/238 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06918083 | Smith |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas W. Smith (Fredericksburg, Virginia) |
| ABSTRACT | Enclosed is a tool that is used to review and/or alter electronic documents each of which may have a different format. The mark-up tool is provided with a color-coded scheme to highlight where an electronic document is to be changed and to indicate the status of the change. |
| FILED | Thursday, May 24, 2001 |
| APPL NO | 09/864819 |
| ART UNIT | 2179 — Graphical User Interface and Document Processing |
| CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/511 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06916455 | Segelke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brent W. Segelke (San Ramon, California); Heike I. Krupka (Livermore, California); Bernhard Rupp (Livermore, California) |
| ABSTRACT | A kit for prescreening protein concentration for crystallization includes a multiplicity of vials, a multiplicity of pre-selected reagents, and a multiplicity of sample plates. The reagents and a corresponding multiplicity of samples of the protein in solutions of varying concentrations are placed on sample plates. The sample plates containing the reagents and samples are incubated. After incubation the sample plates are examined to determine which of the sample concentrations are too low and which the sample concentrations are too high. The sample concentrations that are optimal for protein crystallization are selected and used. |
| FILED | Wednesday, August 14, 2002 |
| APPL NO | 10/218764 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/245.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916502 | Moore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Karen A. Moore (Idaho Falls, Idaho); Raymond A. Zatorski (East Hampton, Connecticut) |
| ABSTRACT | Systems and methods for applying a coating to an interior surface of a conduit. In one embodiment, a spray gun configured to apply a coating is attached to an extension arm which may be inserted into the bore of a pipe. The spray gun may be a thermal spray gun adapted to apply a powder coating. An evacuation system may be used to provide a volume area of reduced air pressure for drawing overspray out of the pipe interior during coating. The extension arm as well as the spray gun may be cooled to maintain a consistent temperature in the system, allowing for more consistent coating. |
| FILED | Monday, February 11, 2002 |
| APPL NO | 10/074355 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/236 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916570 | Vaughey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | John Vaughey (Elmhurst, Illinois); Michael Krumpelt (Naperville, Illinois); Xiaoping Wang (Downers Grove, Illinois); J. David Carter (Bolingbrook, Illinois) |
| ABSTRACT | An oxygen ion conducting ceramic oxide that has applications in industry including fuel cells, oxygen pumps, oxygen sensors, and separation membranes. The material is based on the idea that substituting a dopant into the host perovskite lattice of (La,Sr)MnO3 that prefers a coordination number lower than 6 will induce oxygen ion vacancies to form in the lattice. Because the oxygen ion conductivity of (La,Sr)MnO3 is low over a very large temperature range, the material exhibits a high overpotential when used. The inclusion of oxygen vacancies into the lattice by doping the material has been found to maintain the desirable properties of (La,Sr)MnO3, while significantly decreasing the experimentally observed overpotential. |
| FILED | Tuesday, July 27, 2004 |
| APPL NO | 10/900054 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916665 | Bayley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Hagan P. Bayley (College Station, Texas); Stefan G. Howorka (College Station, Texas); Liviu Movileanu (Bryan, Texas) |
| ABSTRACT | Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample. |
| FILED | Monday, February 12, 2001 |
| APPL NO | 09/781697 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916982 | Loewe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Robert S. Loewe (Morrisville, North Carolina); Kin-ya Tomizaki (Raleigh, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | The present invention provides methods, compounds, and compositions for the synthesis of light harvesting arrays, such arrays comprising: (a) a first substrate comprising a first electrode; and (b) a layer of light harvesting rods electrically coupled to said first electrode, each of said light harvesting rods comprising a polymer of Formula I: X1Xm+1)m (I) wherein m is at least 1; X1 is a charge separation group, and X2 through Xm+1 are chromophores. At least one of X2 through Xm+1 has at least one perylene group coupled thereto. |
| FILED | Thursday, June 06, 2002 |
| APPL NO | 10/164474 |
| ART UNIT | 1753 — Organic Chemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917010 | Milewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
| INVENTOR(S) | John O. Milewski (Santa Fe, New Mexico); Vivek R. Dave′ (Los Alamos, New Mexico); Dane Christensen (Livermore, California); Robert W. Carpenter, II (Los Alamos, New Mexico) |
| ABSTRACT | The present invention includes a method for brazing of two objects or heat treatment of one object. First, object or objects to be treated are selected and initial conditions establishing a relative geometry and material characteristics are determined. Then, a first design of an optical system for directing heat energy onto the object or objects is determined. The initial conditions and first design of the optical system are then input into a optical ray-tracing computer program. The program is then run to produce a representative output of the heat energy input distribution to the object or objects. The geometry of the object or objects, material characteristics, and optical system design are then adjusted until an desired heat input is determined. |
| FILED | Tuesday, April 29, 2003 |
| APPL NO | 10/425288 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric heating 219/85.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917043 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Clarence E. Thomas (Knoxville, Tennessee); Larry R. Baylor (Farragut, Tennessee); Edgar Voelkl (Oak Ridge, Tennessee); Michael L. Simpson (Knoxville, Tennessee); Michael J. Paulus (Knoxville, Tennessee); Douglas Lowndes (Knoxville, Tennessee); John Whealton (Oak Ridge, Tennessee); John C. Whitson (Clinton, Tennessee); John B. Wilgen (Oak Ridge, Tennessee) |
| ABSTRACT | Systems and method are described for addressable field emission array (AFEA) chips. A plurality of individually addressable cathodes are integrated with an electrostatic focusing stack and/or a plurality of detectors on the addressable field emission array. The systems and methods provide advantages including the avoidance of space-charge blow-up. |
| FILED | Monday, September 30, 2002 |
| APPL NO | 10/260321 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/398 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917209 | Ellison |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Energy Conversion Devices, Inc. (Rochester Hills, Michigan) |
| INVENTOR(S) | Timothy Ellison (Brandon Township, Oakland County, Michigan) |
| ABSTRACT | A non-contacting capacitive diagnostic device includes a pulsed light source for producing an electric field in a semiconductor or photovoltaic device or material to be evaluated and a circuit responsive to the electric field. The circuit is not in physical contact with the device or material being evaluated and produces an electrical signal characteristic of the electric field produced in the device or material. The diagnostic device permits quality control and evaluation of semiconductor or photovoltaic device properties in continuous manufacturing processes. |
| FILED | Saturday, September 15, 2001 |
| APPL NO | 09/953477 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Measuring and testing 324/750 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917726 | Levene et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Michael J. Levene (Ithaca, New York); Jonas Korlach (Ithaca, New York); Stephen W. Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Watt W. Webb (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/259268 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917943 | Butler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Limit Point Systems, Inc. (Livermore, California) |
| INVENTOR(S) | David M. Butler (Livermore, California) |
| ABSTRACT | A data model including a first table to represent an entity type with a column in the table for a respective attribute of the entity type, and having rows entered with attribute data. The data model also includes a row graph which represents an ordering relationship between the rows of the first table, and a column graph which represents an ordering relationship between columns of the first table. Further, the column graph is a row graph from a second table. |
| FILED | Friday, May 11, 2001 |
| APPL NO | 09/852781 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06916936 | Hedrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | James Lupton Hedrick (Peasanton, California); Pinar Kilickiran (Ulm, Germany); Gregory Walker Nyce (San Jose, California); Robert M. Waymouth (Palo Alto, California) |
| ABSTRACT | A method is provided for carrying out depolymerization of a polymer containing electrophilic linkages in the presence of a catalyst and a nucleophilic reagent, wherein production of undesirable byproducts resulting from polymer degradation is minimized. The reaction can be carried out at a temperature of 80° C. or less, and generally involves the use of an organic, nonmetallic catalyst, thereby ensuring that the depolymerization product(s) are substantially free of metal contaminants. In an exemplary depolymerization method, the catalyst is a carbene compound such as an N-heterocyclic carbene, or is a precursor to a carbene compound. The method provides an important alternative to current recycling techniques such as those used in the degradation of polyesters, polyamides, and the like. |
| FILED | Thursday, January 30, 2003 |
| APPL NO | 10/356440 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/316.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916982 | Loewe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Robert S. Loewe (Morrisville, North Carolina); Kin-ya Tomizaki (Raleigh, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | The present invention provides methods, compounds, and compositions for the synthesis of light harvesting arrays, such arrays comprising: (a) a first substrate comprising a first electrode; and (b) a layer of light harvesting rods electrically coupled to said first electrode, each of said light harvesting rods comprising a polymer of Formula I: X1Xm+1)m (I) wherein m is at least 1; X1 is a charge separation group, and X2 through Xm+1 are chromophores. At least one of X2 through Xm+1 has at least one perylene group coupled thereto. |
| FILED | Thursday, June 06, 2002 |
| APPL NO | 10/164474 |
| ART UNIT | 1753 — Organic Chemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917431 | Soljacic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Marin Soljacic (Somerville, Massachusetts); Shanhui Fan (Somerville, Massachusetts); Mihai Ibanescu (Piatra Neamt, Romania); Steven G. Johnson (St. Charles, Illinois); John D. Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | A photonic crystal optical switch having a periodic dielectric structure including at least one input waveguide. First and second waveguide arms branch from the input waveguide in which the relative optical path lengths of electromagnetic radiation within the arms are controlled by stimuli. At least one output waveguide that combines the electromagnetic radiation propagating within the first and second waveguide arms. |
| FILED | Wednesday, May 15, 2002 |
| APPL NO | 10/146430 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/477 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917726 | Levene et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Michael J. Levene (Ithaca, New York); Jonas Korlach (Ithaca, New York); Stephen W. Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Watt W. Webb (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/259268 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917883 | Ruddle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Frank H. Ruddle (New Haven, Connecticut); Kenta Sumiyama (New Haven, Connecticut); Chang-Bae Kim (New Haven, Connecticut) |
| ABSTRACT | A method is described for efficiently searching non-coding DNA for known control elements. Short conserved DNA sequences can be identified among 3 or more species by selecting DNA sequences from species having a total genetic distance larger than one substitution per site at a neutrally evolving region and calculating the total substitutions using pair-wise genetic distances, with the pairs for comparison selected based on phylogenetic relationships. |
| FILED | Wednesday, January 15, 2003 |
| APPL NO | 10/345080 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06917041 | Doty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John P. Doty (Bedford, Massachusetts); George R. Ricker, Jr. (Cambridge, Massachusetts); Barry E. Burke (Lexington, Massachusetts); Gregory Y. Prigozhin (Belmont, Massachusetts) |
| ABSTRACT | An event-driven X-ray CCD imager device uses a floating-gate amplifier or other non-destructive readout device to non-destructively sense a charge level in a charge packet associated with a pixel. The output of the floating-gate amplifier is used to identify each pixel that has a charge level above a predetermined threshold. If the charge level is above a predetermined threshold the charge in the triggering charge packet and in the charge packets from neighboring pixels need to be measured accurately. A charge delay register is included in the event-driven X-ray CCD imager device to enable recovery of the charge packets from neighboring pixels for accurate measurement. When a charge packet reaches the end of the charge delay register, control logic either dumps the charge packet, or steers the charge packet to a charge FIFO to preserve it if the charge packet is determined to be a packet that needs accurate measurement. A floating-diffusion amplifier or other low-noise output stage device, which converts charge level to a voltage level with high precision, provides final measurement of the charge packets. The voltage level is eventually digitized by a high linearity ADC. |
| FILED | Tuesday, March 18, 2003 |
| APPL NO | 10/391061 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/370.90 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917203 | Perotti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Jose M. Perotti (Merritt Island, Florida); Angel Lucena (Orlando, Florida); Curtis Ihlefeld (Orlando, Florida); Bradley Burns (Orlando, Florida); Karin E. Bassignani (Colorado Springs, Colorado) |
| ABSTRACT | A solenoid health monitoring system uses a signal conditioner and controller assembly in one embodiment that includes analog circuitry and a DSP controller. The analog circuitry provides signal conditioning to the low-level raw signal coming from a signal acquisition assembly. Software running in a DSP analyzes the incoming data (recorded current signature) and determines the state of the solenoid whether it is energized, de-energized, or in a transitioning state. In one embodiment, the software identifies key features in the current signature during the transition phase and is able to determine the “health” of the solenoid. |
| FILED | Thursday, August 29, 2002 |
| APPL NO | 10/235020 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Measuring and testing 324/418 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06917839 | Bickford |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Intellectual Assets LLC (Lake Tahoe, Nevada) |
| INVENTOR(S) | Randall L. Bickford (Orangevale, California) |
| ABSTRACT | A system and method which partitions a parameter estimation model, a fault detection model, and a fault classification model for a process surveillance scheme into two or more coordinated submodels together providing improved diagnostic decision making for at least one determined operating mode of an asset. |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600721 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 06916469 | Rojas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); Waterbury Companies, Inc. (Waterbury, Connecticut) |
| INVENTOR(S) | Maria Guadalupe Rojas (Metairie, Louisiana); Juan A. Morales-Ramos (Metairie, Louisiana); Ligia M. Hernandez (Kenner, Louisiana); Jonathan D. Peters (Independence, Louisiana) |
| ABSTRACT | Ant foods mixed together in a matrix suitable to be used as baits for ants are provided. This ant matrix is preferred by ants over naturally-occurring foods such as other known ant matrices. It comprises protein, carbohydrate, fat and sterol as ant-preferred nutrients and uric acid as a bait enhancing agent is carried in a unique gel system that is specifically attractive to insects. Methods of controlling ants using such matrices to deliver ant toxins are also provided. |
| FILED | Thursday, February 20, 2003 |
| APPL NO | 10/370954 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/84 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916617 | Gonsalves et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Dennis Gonsalves (Geneva, New York); Kai-Shu Ling (Geneva, New York) |
| ABSTRACT | The invention features a method of detecting the presence of a grapevine leafroll virus in a sample using immunological or nucleic-acid based methodologies. |
| FILED | Monday, December 31, 2001 |
| APPL NO | 10/039112 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 06916646 | Fowler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Genencor International, Inc. (Palo Alto, California) |
| INVENTOR(S) | Timothy Fowler (San Carlos, California); Stuart C. Causey (Palo Alto, California) |
| ABSTRACT | Methods are provided for preparing improved fermentation strains of the family Enterobacteriaceae which comprise the steps of eliminating the cryptic plasmid from the progenitor strain thereby creating the improved strain. Methods for reducing the mobilization properties of resident plasmids in an Enterobacteriaceae strain containing a cryptic plasmid are also provided. The present invention provides the nucleic acid sequence of pS, a cryptic plasmid found in Pantoea which can be used to identify the cryptic plasmid in strains of Enterobacteriaceae. |
| FILED | Monday, June 23, 1997 |
| APPL NO | 08/876132 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/245 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916902 | Inbasekaran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Dow Global Technologies Inc. (Midland, Michigan) |
| INVENTOR(S) | Michael Inbasekaran (Midland, Michigan); Yang Cheng (Saginaw, Michigan); Scott Gaynor (Midland, Michigan); Michelle L. Hudack (Grand Blanc, Michigan); Chun Wang (Midland, Michigan); Dean M. Welsh (Midland, Michigan); Weishi Wu (Midland, Michigan) |
| ABSTRACT | A composition comprising a polymer comprising a repeat unit of Formula I: wherein R1 is independently in each occurrence H, C1-40 hydrocarbyl or C3-40 hydrocarbyl containing one or more S, N, O, P or Si atoms, or both of R1 together with the 9-carbon on the fluorene, may form a C5-20 ring structure which may contain one or more S, N, or O atoms; R2 is independently in each occurrence C1-20 hydrocarbyl, C1-20 hydrocarbyloxy, C1-20 thioether, C1-20 hydrocarbyloxycarbonyl, C1-20 hydrocarbylcarbonyloxy, or cyano; a is independently in each occurrence, 0 or 1; X is O, S, SO2, C(R3)2 or N—R3 wherein R3 is aryl or substituted aryl of C6 to C40, aralkyl of C6 to C24, or alkyl of C1 to C24. Preferably R3 is aryl of C6 to C24 and more preferably R3 is an alkylated aryl group of C6 to C24; Ar is an aryl or heteroaryl group of C6 to C40 or substituted aryl or heteroaryl group of C6 to C40, preferably C6-C24, and most preferably C6-C4. Y is a conjugated moiety that can vary in each occurrence of the repeat unit. |
| FILED | Thursday, December 19, 2002 |
| APPL NO | 10/324270 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 528/397 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 06916802 | Shayman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Genzyme Corporation (Cambridge, Massachusetts); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | James A. Shayman (Ann Arbor, Michigan); David J. Harris (Lexington, Massachusetts); Craig Siegel (Woburn, Massachusetts); Carol A. Nelson (Westford, Massachusetts); Diane P. Copeland (North Billerica, Massachusetts) |
| ABSTRACT | The present invention provides amino ceramide-like compounds which inhibit glucosyl ceramide (GlyCer) formation by inhibiting the enzyme GlyCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer synthase inhibition activity and are therefore useful in therapeutic methods for treating various conditions and diseases associated with altered glycosphingolipid levels. |
| FILED | Wednesday, May 05, 2004 |
| APPL NO | 10/839497 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/210.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 06917343 | Sanchez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Titan Aerospace Electronics Division (Greenbelt, Maryland) |
| INVENTOR(S) | Victor C. Sanchez (Laurel, Maryland); William E. McKinzie, III (Fulton, Maryland); Rodolfo E. Diaz (Phoenix, Arizona) |
| ABSTRACT | A low profile antenna system includes an artificial magnetic conductor comprising a frequency selective surface (FSS) having an effective sheet capacitance which is electronically variable to control resonant frequency of the AMC and the resonant frequency of an antenna element positioned adjacent to the FSS. |
| FILED | Tuesday, September 17, 2002 |
| APPL NO | 10/246198 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/795 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 06917839 | Bickford |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Intellectual Assets LLC (Lake Tahoe, Nevada) |
| INVENTOR(S) | Randall L. Bickford (Orangevale, California) |
| ABSTRACT | A system and method which partitions a parameter estimation model, a fault detection model, and a fault classification model for a process surveillance scheme into two or more coordinated submodels together providing improved diagnostic decision making for at least one determined operating mode of an asset. |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600721 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 06917948 | Campbell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Leo J. Campbell (Arlington, Virginia) |
| ABSTRACT | Systems and methods are disclosed for providing secure electronic archiving of customer (120) data over a network (110). Electronic postmarks are used to track archival of the data, access request for the archived (101) data, and fulfillment of the access requests. |
| FILED | Friday, September 07, 2001 |
| APPL NO | 10/362506 |
| ART UNIT | 2134 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/104.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 06916476 | Livingston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Institute (New York, New York) |
| INVENTOR(S) | Philip Ordway Livingston (New York, New York); Friedhelm Helling (New York, New York) |
| ABSTRACT | This invention provides a vaccine for stimulating or enhancing in a subject to which the vaccine is administered, production of an antibody which recognizes a ganglioside, comprising an amount of ganglioside or oligosaccharide portion thereof conjugated to an immunogenic protein effective to stimulate or enhance antibody production in the subject, an effective amount of adjuvant and a pharmaceutically acceptable vehicle. |
| FILED | Wednesday, June 07, 1995 |
| APPL NO | 08/481809 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/194.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916631 | Burgeson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Robert E. Burgeson (Marblehead, Massachusetts); David Wolfe Wagman (Melrose, Massachusetts) |
| ABSTRACT | Antibodies directed against laminin B1k are provided. |
| FILED | Friday, May 07, 2004 |
| APPL NO | 10/841139 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06916821 | Bear et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Mark F. Bear (Bristol, Rhode Island); Kimberly M. Huber (Dallas, Texas); Stephen T. Warren (Atlanta, Georgia) |
| ABSTRACT | mGluR5 antagonists are used for the treatment and prevention of disorders, including Fragile X, autism, mental retardation, schizophrenia and Down's Syndrome. The methods of the invention can be used to treat epilepsy and anxiety in a human having Fragile X syndrome, autism, mental retardation, schizophrenia and Down's Syndrome. |
| FILED | Friday, April 04, 2003 |
| APPL NO | 10/408771 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 12, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050712.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page