FedInvent™ Patents
Patent Details for Tuesday, September 06, 2005
This page was updated on Sunday, March 26, 2023 at 07:48 PM GMT
Department of Defense (DOD)
US 06938290 | McKinney et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Richard A. McKinney (Clarksville, Virginia); Barbara J. McKinney (Clarksvile, Virginia); David P. Colvin (Cary, North Carolina) |
ABSTRACT | Impact energy forces to the spine are reduced through the use of multiple overlying pliable impact energy absorbing layers. Each layer comprises a plurality of cells that are in fluid communication which provides for a valved transfer of fluid between the cells. Additionally, each layer has a different durometer. |
FILED | Monday, April 21, 2003 |
APPL NO | 10/419560 |
ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Beds 05/654 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06938325 | Tanielian |
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APPLICANT(S) | |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Minas H. Tanielian (Bellevue, Washington) |
ABSTRACT | In one embodiment, a method for fabricating electromagnetic meta-materials includes applying first and second array of electromagnetically reactive patterns to first and second non-conducting surfaces, wherein the first array includes at least one of a split ring resonator pattern, a square split ring resonator pattern, and a swiss roll pattern, and the second array includes a thin parallel wire pattern. The first and second non-conducting surfaces are joined together such that the first and second non-conducting surfaces bearing the first and second arrays of electromagnetically reactive patterns are commonly oriented. Alternately, a method may further include slicing between elements of the first and second arrays of electromagnetically reactive patterns in a plane perpendicular to the first and second surfaces to form a plurality of slices, rotating at least one of the slices, and applying a third array of electromagnetically reactive patterns to a third non-conducting surface. |
FILED | Friday, January 31, 2003 |
APPL NO | 10/356934 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/602.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06938484 | Najafi et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Khalil Najafi (Ann Arbor, Michigan); Junseok Chae (Ann Arbor, Michigan) |
ABSTRACT | A high-sensitivity and low-noise micromachined capacitive lateral accelerometer device having an input axis and a monolithic, three-axis accelerometer utilizing the device are provided. The device includes at least one electrode having a side surface normal to the input axis. A relatively large proofmass has at least one side surface normal to the input axis and extends along a width of the proofmass. The proofmass is movable against acceleration relative to the at least one electrode due to inertial force along the input axis to obtain a capacitive variation between the at least one electrode and the proofmass. The side surfaces are spaced apart to define a narrow, high-aspect ratio sensing gap which extends along substantially the entire width of the proofmass. The proofmass forms a sense capacitor with the at least one electrode. |
FILED | Friday, January 16, 2004 |
APPL NO | 10/760025 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/514.320 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06938552 | Tom et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Joe G. Tom (Vicksburg, Mississippi); Philip G. Malone (Vicksburg, Mississippi); Charles A. Weiss, Jr. (Clinton, Mississippi); Steven L. Larson (Vicksburg, Mississippi) |
ABSTRACT | Structure incorporating lead is fabricated from specially prepared components such that mobility of the lead is impeded when the structure is exposed to an unprotected environment such as weathering outdoors or saltwater. In a preferred embodiment, a bullet or bullet core is swaged from a number of bunched electroplated fine lead or lead-alloy wires placed in a die. The lead or lead-alloy wires may be fabricated from lead or lead-alloy wool. The lead alloy may comprise zinc and antimony. The electroplating process plates zinc on the fine wires and may plate a zinc alloy such as zinc-aluminum. The plated surface may be coated with a corrosion resistant coating such as molybdenum phosphate. In addition to bullets and bullet cores, fishing weights, lead shielding, counterweights, ballast, and other lead containing structure may be fabricated or treated using methods and materials of the present invention. |
FILED | Tuesday, June 17, 2003 |
APPL NO | 10/462707 |
ART UNIT | 1775 — Printing/Measuring and Testing |
CURRENT CPC | Ammunition and explosives 12/517 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939107 | Mongillo, Jr. et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Young H. Chon (Manchester, Connecticut) |
ABSTRACT | A turbine engine component, such as a blade or vane, has a system for cooling a trailing edge portion thereof. The system includes a plurality of rows of pedestals which vary in density along a span of the component. In a preferred embodiment of the present invention, the number of rows of pedestals increases as one moves along the span of the component from an inner diameter region to an outer diameter region. |
FILED | Wednesday, November 19, 2003 |
APPL NO | 10/717806 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Fluid reaction surfaces 416/96.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939505 | Musso et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Christopher S. Musso (Concord, Massachusetts); Thomas W. Eagar (Belmont, Massachusetts) |
ABSTRACT | Channeled articles having very small diameter channels spaced very closely can be made by packing elongated cores in a fixture, clamping them, and then introducing matrix material around the cores. The matrix material is formed into a unitary body and solidified. The cores are pulled out, leaving open channels where they had been. Some core and matrix combinations will permit the cores to be pulled out. Others require a core release coating to be applied to the cores. The cores can be metal or ceramic or polymer, and the matrix can be metal or ceramic or polymer. The cores can be solid, or hollow. Rather than pulling the cores out, if they are polymer, they can be burned out. The matrix can be formed by liquid state, solid state, or hybrid liquid/solid state techniques. A related technique uses hollow cores, which are not pulled out, but which remain in the body after unification. For such tube-walled articles, the matrix can be formed similarly. Rather than insuring core release, core retention is required. Such may occur due to the nature of the materials, or a specific core retention coating may be provided. Articles made of such material include heat sinks for semiconductor devices, light-weight structural components, thermally activated actuators, etc. Very small channel diameters and very large length to opening aspect ratios can be achieved. Heat exchange fluid can be compressed and pumped through such an article at very high efficiencies, to cool semiconductor devices. |
FILED | Tuesday, March 12, 2002 |
APPL NO | 10/096091 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/635 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939533 | Contag et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Portola Valley, California) |
ABSTRACT | Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen. |
FILED | Wednesday, July 24, 2002 |
APPL NO | 10/205218 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939543 | Fischer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Henry M. Jackson Foundation for the Advancement of Military Medicine (Rockville, Maryland); Sunol Molecular Corporation (Miramar, Florida) |
INVENTOR(S) | Gerald W. Fischer (Bethesda, Maryland); Richard F. Schuman (Gaithersburg, Maryland); Hing Wong (Weston, Florida); Jeffrey R. Stinson (Davie, Florida) |
ABSTRACT | The present invention encompasses monoclonal and chimeric antibodies that bind to lipoteichoic acid of Gram positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro and enhance protection from lethal infection in vivo. The mouse monoclonal antibody has been humanized and the resulting chimeric antibody provides a previously unknown means to diagnose, prevent and/or treat infections caused by gram positive bacteria bearing lipoteichoic acid. This invention also encompasses a peptide mimic of the lipoteichoic acid epitope binding site defined by the monoclonal antibody. This epitope or epitope peptide mimic identifies other antibodies that may bind to the lipoteichoic acid epitope. Moreover, the epitope or epitope peptide mimic provides a valuable substrate for the generation of vaccines or other therapeutics. |
FILED | Friday, June 29, 2001 |
APPL NO | 09/893615 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939546 | Nauss et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey Nauss (San Diego, California); Robert Reid (Fairfield, Pennsylvania); Marcia Kay Wolf (Silver Spring, Maryland); Scheberazade Sadegh-Nasseri (Baltimore, Maryland) |
ABSTRACT | Assay methods for determining whether a peptide is likely to be immunogenic are based on a computer modeling of binding to a Class II MHC DR1 receptor. This is confirmed by competitive inhibition binding assays. The peptides are useful for eliciting an immune response for vaccination or the production of antibodies or T-cells. |
FILED | Monday, January 26, 1998 |
APPL NO | 09/013077 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939624 | Lamansky et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey); The University of Southern California (Los Angeles, California); The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Sergey Lamansky (Maplewood, Minnesota); Mark E. Thompson (Anaheim, California); Vadim Adamovich (Los Angeles, California); Peter I. Djurovich (Long Beach, California); Chihaya Adachi (Hokkaido, Japan); Marc A. Baldo (Princeton, New Jersey); Stephen R. Forrest (Princeton, New Jersey); Raymond Kwong (Plainsboro, New Jersey) |
ABSTRACT | Emissive phosphorescent organometallic compounds are described that produce improved electroluminescence, particularly in the blue region of the visible spectrum. Organic light emitting devices employing such emissive phosphorescent organometallic compounds are also described. Also described is an organic light emitting layer including a host material having a lowest triplet excited state having a decay rate of less than about 1 per second; a guest material dispersed in the host material, the guest material having a lowest triplet excited state having a radiative decay rate of greater than about 1×105 or about 1×106 per second and wherein the energy level of the lowest triplet excited state of the host material is lower than the energy level of the lowest triplet excited state of the guest material. |
FILED | Tuesday, October 16, 2001 |
APPL NO | 09/978455 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Stock material or miscellaneous articles 428/690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939625 | Marks et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Nôrthwestern University (Evanston, Illinois) |
INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Qinglan Huang (Skokie, Illinois); Ji Cui (Acton, Massachusetts); Jonathan Veinot (Palatine, Illinois) |
ABSTRACT | New organic light-emitting diodes and related electroluminescent devices and methods for fabrication, using siloxane self-assembly techniques. |
FILED | Friday, March 15, 2002 |
APPL NO | 10/099131 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Stock material or miscellaneous articles 428/690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939632 | Arana et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Leonel R. Arana (Cambridge, Massachusetts); Aleksander J. Franz (Winchester, Massachusetts); Klavs F. Jensen (Lexington, Massachusetts); Samuel B. Schaevitz (San Rafael, California); Martin A. Schmidt (Reading, Massachusetts) |
ABSTRACT | A micromachined device for efficient thermal processing at least one fluid stream includes at least one fluid conducting tube having at least a region with wall thickness of less than 50 μm. The device optionally includes one or more thermally conductive structures in thermal communication with first and second thermally insulating portions of the fluid conducting tube. The device also may include a thermally conductive region, and at least a portion of the fluid conducting tube is disposed within the region. A plurality of structures may be provided projecting from a wall of the fluid conducting tube into an inner volume of the tube. The structures enhance thermal conduction between a fluid within the tube and a wall of the tube. A method for fabricating, from a substrate, a micromachined device for processing a fluid stream allows the selective removal of portions of the substrate to provide desired structures integrated within the device. As an example, the micromachined device may be adapted to efficiently react fluid reactants to produce fuel for a fuel cell associated with the device, resulting in a system capable of conversion of chemical to electrical energy. |
FILED | Monday, August 06, 2001 |
APPL NO | 09/923139 |
ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/17 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939647 | Jow et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | T. Richard Jow (Potomac, Maryland); Shengshui Zhang (Olney, Maryland); Kang Xu (North Potomac, Maryland); Michael S. Ding (Gaithersburg, Maryland) |
ABSTRACT | Non-aqueous electrolyte solutions capable of protecting lithium metal and lithium-inserted carbonaceous electrodes include an electrolyte salt, preferably LiPF6, and a non-aqueous electrolyte solvent mixture comprising at least one of trialkyl phosphites, one or more cyclic or/and linear carbonates, and optionally other additives, such as, gelling agents, ionically conductive solid polymers, and other additives. The trialkyl phosphites have the following general formula: wherein the oxidation number of the phosphorus atom is III (three), R1, R2, and R3 are the same or different, independently selected from linear or branched alkyl groups having 1 to 4 carbon atoms, optionally but not limited to, with one or more of the alkyl substituents being substituted by one or more halogen atoms, preferably fluorine atoms. |
FILED | Friday, February 01, 2002 |
APPL NO | 10/060139 |
ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/341 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939723 | Basceri et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
INVENTOR(S) | Cem Basceri (Boise, Idaho); Gurtej Sandhu (Boise, Idaho) |
ABSTRACT | Described herein is a method for producing a haze-free (Ba, Sr)TiO3 (BST) film, and devices incorporating the same. In one embodiment, the BST film is made haze-free by depositing the film with a substantially uniform desired crystal orientation, for example, (100), preferably by forming the film by metal-organic chemical vapor deposition at a temperature greater than about 580° C. at a rate of less than about 80 Å/min, to result in a film having about 50 to 53.5 atomic percent titanium. In another embodiment, whereby the BST film serves as a capacitor for a DRAM memory cell, a desired {100} orientation is induced by depositing the bottom electrode over a nucleation layer of NiO, which gives the bottom electrode a preferential {100} orientation. BST is then grown over the {100} oriented bottom electrode also with a {100} orientation. A nucleation layer of materials such as Ti, Nb and Mn can also be provided over the bottom electrode and beneath the BST film to induce smooth, haze-free BST growth. Haze-free BST film can also be favored by forming the bottom electrode at high temperatures close to those used for BST deposition, and without a vacuum break between the bottom electrode and BST deposition. |
FILED | Thursday, July 03, 2003 |
APPL NO | 10/615524 |
ART UNIT | 2823 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Semiconductor device manufacturing: Process 438/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939756 | Chung et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); Auburn University (Auburn, Alabama) |
INVENTOR(S) | Gilyong Chung (Tampa, Florida); Chin Che Tin (Auburn, Alabama); John R. Williams (Opelika, Alabama); Kyle McDonald (Nashville, Tennessee); Massimiliano Di Ventra (Blacksburg, Virginia); Robert A. Weller (Brentwood, Tennessee); Sokrates T. Pantelides (Franklin, Tennessee); Leonard C. Feldman (Nashville, Tennessee) |
ABSTRACT | A method for manufacturing a silicon carbide semiconductor device. In one embodiment, the method includes the following steps: a layer of silicon dioxide is formed on a silicon carbide substrate to create a silicon dioxide/silicon carbide interface and then nitrogen is incorporated at the silicon dioxide/silicon carbide interface for reduction in an interface trap density. The silicon carbide substrate, in one embodiment, includes a n-type 4H-silicon carbide. |
FILED | Monday, March 26, 2001 |
APPL NO | 09/818193 |
ART UNIT | 2823 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Semiconductor device manufacturing: Process 438/198 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940187 | Escobar et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Gerardo Escobar (Stoughton, Massachusetts); Alex M. Stankovic (Boston, Massachusetts); Paolo Mattavelli (Padua, Italy) |
ABSTRACT | A controller (236) for an uninterruptible power supply (UPS) compensates for harmonic distortion in the output current (224,26,228). The controller also provides a control vector (230) also with input from the adaptation processor (234). |
FILED | Thursday, December 13, 2001 |
APPL NO | 10/203950 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electrical transmission or interconnection systems 37/64 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940264 | Ryken, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Marvin L. Ryken, Jr. (Oxnard, California); Albert F. Davis (Ventura, California) |
ABSTRACT | A near field probe for testing installed components of an electromagnetic radiating system on a missile. The probe design comprises a diode antenna with a balun. The probe utilizes a dual diode arrangement which provides approximately twice the output voltage as the previous probe. The probe may then be placed further away from the radiating system under test. |
FILED | Thursday, January 29, 2004 |
APPL NO | 10/769669 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Electricity: Measuring and testing 324/95 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940450 | Blunt et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Shannon D. Blunt (Alexandria, Virginia); Karl R. Gerlach (Chesapeake, Maryland) |
ABSTRACT | A method for processing a received, modulated pulse (i.e. waveform) that requires predictive deconvolution to resolve a scatterer from noise and other scatterers includes receiving a return signal; obtaining L+(2M−1)(N−1) samples y of the return signal, where y(l)={tilde over (x)}T(l)s+v(l); applying RMMSE estimation to each successive N samples to obtain initial impulse response estimates [{circumflex over (x)}1{−(M−1)(N−1)}, . . . , {circumflex over (x)}1{−1}, {circumflex over (x)}1{0}, . . . , {circumflex over (x)}1{L−1}, {circumflex over (x)}1{L}, . . . , {circumflex over (x)}1{L−1+(M−1)(N−1)}]; computing power estimates {circumflex over (ρ)}1(l)=|{circumflex over (x)}1(l)|2 for l=−(M−1)(N−1), . . . , L−1+(M−1)(N−1); computing MMSE filters according to w(l)=ρ(l)(C(l)+R)−1s, where ρ(l)=|x(l)|2 is the power of x(l), and R=E[v(l)vH(l)] is the noise covariance matrix; applying the MMSE filters to y to obtain [{circumflex over (x)}2{−(M−2)(N−1)}, . . . , {circumflex over (x)}2{−1}, {circumflex over (x)}2{0}, . . . , {circumflex over (x)}2{L−1}, {circumflex over (x)}2{L}, . . . , {circumflex over (x)}2{L−1+(M−2)(N−1)}]; and repeating (d)-(f) for subsequent reiterative stages until a desired length-L range window is reached, thereby resolving the scatterer from noise and other scatterers. The RMMSE predictive deconvolution approach provides high-fidelity impulse response estimation. The RMMSE estimator can reiteratively estimate the MMSE filter for each specific impulse response coefficient by mitigating the interference from neighboring coefficients that is a result of the temporal (i.e. spatial) extent of the transmitted waveform. The result is a robust estimator that adaptively eliminates the spatial ambiguities that occur when a fixed receiver filter is used. |
FILED | Tuesday, September 30, 2003 |
APPL NO | 10/673343 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/195 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940598 | Christel et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cepheid (Sunnyvale, California) |
INVENTOR(S) | Lee A. Christel (Palo Alto, California); M. Allen Northrup (Berkeley, California); Kurt E. Petersen (Santa Clara, California); William A. McMillan (Cupertino, California); Gregory T. A. Kovacs (Stanford, California); Steven J. Young (Los Gatos, California); Ronald Chang (Redwood City, California); Douglas B. Dority (Mill Valley, California); Raymond T. Hebert (Los Gatos, California); Gregory J. Kintz (Mountain View, California) |
ABSTRACT | An apparatus for thermally controlling and optically interrogating a reaction mixture includes a vessel [2] having a chamber [10] for holding the mixture. The apparatus also includes a heat-exchanging module [37] having a pair of opposing thermal plates [34A, 34B] for receiving the vessel [2] between them and for heating/and or cooling the mixture contained in the vessel. The module [37] also includes optical excitation and detection assemblies [46,48] positioned to optically interrogate the mixture. The excitation assembly [46] includes multiple light sources [100] and a set of filters for sequentially illuminating labeled analytes in the mixture with excitation beams in multiple excitation wavelength ranges. The detection assembly [48] includes multiple detectors [102] and a second set of filters for detecting light emitted from the chamber [10] in multiple emission wavelength ranges. The optics assemblies [46,48] thus provide a multi-channel system for detecting a plurality of different target analytes in the mixture. |
FILED | Monday, April 08, 2002 |
APPL NO | 10/119228 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/417 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940639 | Belyanin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
INVENTOR(S) | Alexey Belyanin (College Station, Texas); Alfred Yi Cho (Summit, New Jersey); Claire F. Gmachl (Princeton, New Jersey); Oana Malis (Chatham, New Jersey); Milton L. Peabody, Jr. (Somerville, New Jersey); Arthur Mike Sergent (New Providence, New Jersey); Deborah Lee Sivco (Warren, New Jersey) |
ABSTRACT | An optical device comprises a cavity resonator and an intracavity ridge waveguide. The ridge waveguide includes a monolithically integrated intersubband core region and a nonlinear mixing region (NMR). In response to external pumping energy the core region generates laser light at a first frequency and in a first transverse mode. In response to the laser light the NMR generates parametric light at a second frequency and in a second transverse mode. For phase matching the effective-refractive-index-versus-ridge-width characteristics of the modes of the laser and the parametric light intersect one another at a phase matching width and so that, at greater widths, the effective refractive index of the mode of the higher frequency light is less than that of the lower frequency light. For true phase matching the width of the ridge is made to be essentially equal to the phase matching width. |
FILED | Monday, March 29, 2004 |
APPL NO | 10/812328 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical: Systems and elements 359/330 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940863 | Xue et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Fei Xue (Davis, California); Julie Taylor (Davis, California); Sung-Joo Ben Yoo (Davis, California) |
ABSTRACT | An edge router for interfacing an optical label switched core IP network with client networks, which may be electronically switched and operate with different protocol. The core network has a limited number of ports, each with an edge router, which receives packets from one or more associated client networks and queues them according to egress port on the core network and optionally additionally according to attribute of service. When a queue has exceed a maximum packet length or a timeout limit assigned to the queue, the packets including their headers are assembled into a super packet for transmission across the core network in optical form, preferably using optical routers incorporating wavelength conversion of payloads and switching according to an attached label. The edge router at the egress port disassembles the super packet into constituent packets for respective destinations on the client network. |
FILED | Monday, January 13, 2003 |
APPL NO | 10/341237 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Multiplex communications 370/401 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940943 | Claus et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Bernhard Erich Hermann Claus (Niskayuna, New York); Ajay Kapur (Clifton Park, New York); Jeffrey Wayne Eberhard (Albany, New York) |
ABSTRACT | An imaging system for performing tomosynthesis on a region of an object comprises an x-ray source, motion controller, an x-ray detector and a processing unit. The x-ray source is positioned at a predetermined distance from the object and continuously moves along a path relative to the object at a plurality of predetermined locations. The x-ray source transmits x-ray radiation through the region of the object. The motion controller is coupled to the x-ray source and continuously moves the x-ray source along the path relative to the object. The x-ray source minimizes vibration in the imaging system due to continuous movement. The x-ray detector is positioned at a predetermined distance from the x-ray source and detects the x-ray radiation transmitted through the region of the object, thus acquiring x-ray image data representative of the region of the object. The processing unit is coupled to the x-ray detector for processing the x-ray image data into at least one tomosynthesis image of the region of the object. |
FILED | Monday, October 07, 2002 |
APPL NO | 10/265489 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/27 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940986 | Belenger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
INVENTOR(S) | Robert V. Belenger (Raynham, Massachusetts); Gennaro R. Lopriore (Somerset, Massachusetts) |
ABSTRACT | An apparatus and method for remotely and automatically adjusting the volume of a remotely controlled audio device. In one embodiment, the apparatus comprises a sensor circuit for continuously detecting audio signals generated by the audio device, a difference circuit for determining the difference between the amplitude of the detected audio signals and a reference audio signal amplitude and for outputting a signal that represents this difference, a difference signal transfer circuit having an input for receiving the difference signal and an output wherein the difference signal is coupled to the output when the sensor circuit outputs a signal that indicates an audio signal has been detected, and a control circuit for generating a control signal that effects attenuation, augmentation or maintenance of the amplitude of the audio signals generated by the audio device in accordance with the difference signal when the sensor circuit detects an audio signal. |
FILED | Friday, March 16, 2001 |
APPL NO | 09/808973 |
ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Electrical audio signal processing systems and devices 381/104 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940994 | Nixon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Matthew D. Nixon (Albuquerque, New Mexico); Rohan Loveland (Albuquerque, New Mexico) |
ABSTRACT | A passive, real-time obstacle detection system is provided that determines the presence of small, curvilinear objects such as power lines. The system generally comprises a payload system having an infrared image detection system, a crew interface having a display for the images, and software algorithms that perform image processing on the pixel images. The software algorithms employ Cellular Automata (CA) techniques to resolve the direction vectors of sub-pixels, and as such, line segments are produced that are subsequently linked for display to the flight crew. The CA techniques are further based on the “Game of Life” model, wherein local rules are used to determine how pixels evolve, or propagate along a line. The linked lines are then displayed for the flight crew so that evasive maneuvers can be performed as necessary. |
FILED | Monday, January 07, 2002 |
APPL NO | 10/040594 |
ART UNIT | 2625 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941017 | Ferguson |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Tektronix, Inc. (Beaverton, Oregon) |
INVENTOR(S) | Kevin M. Ferguson (Beaverton, Oregon) |
ABSTRACT | Temporal processing for realtime human vision system behavioral modeling is added at the input of a spatial realtime human vision system behavioral modeling algorithm. The temporal processing includes a linear and a non-linear temporal filter in series in each of a reference channel and a test channel, the input to the reference channel being a reference image signal and the input to the test channel being a test image signal that is an impaired version of the reference image signal. The non-linear temporal filter emulates a process with neural attack and decay to compensate for a shift in peak sensitivity and for frequency doubling in a spatio-temporal sensitivity function. The linear temporal filter accounts for the remaining subtleties in the spatio-temporal sensitivity function. |
FILED | Tuesday, September 18, 2001 |
APPL NO | 09/955614 |
ART UNIT | 2625 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941196 | Garypie et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Stephen A. Garypie (Garden City, New York); Steven Kelmenson (Hicksville, New York) |
ABSTRACT | A method of finding a vertical velocity of a vehicle by first forming two cost functions from three pulse return times. An independently determined approximate vertical velocity and a Fletcher-Powell estimation technique are used on the first cost function, to select a minimum velocity of the first cost function. The selected minimum velocity, two calculated velocities from the selected minimum velocity, and a Fletcher-Powell estimation technique are used on the second cost function, to select a minimum velocity of the second cost function. The selected minimum velocity of the second cost function is taken as the vertical velocity of the vehicle. |
FILED | Tuesday, January 13, 2004 |
APPL NO | 10/756885 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/21 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941303 | Perrizo |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
INVENTOR(S) | William K. Perrizo (Fargo, North Dakota) |
ABSTRACT | A system and method to take data, which is in the form of an n-dimensional array of binary data where the binary data is comprised of bits that are identified by a bit position within the n-dimensional array, and create one file for each bit position of the binary data while maintaining the bit position identification and to store the bit with the corresponding bit position identification from the binary data within the created filed. Once this bit-sequential format of the data is achieved, the formatted data is structured into a tree format that is data-mining-ready. The formatted data is structured by dividing each of the files containing the binary data into quadrants according to the bit position identification and recording the count of 1-bits for each quadrant on a first level. Then, recursively dividing each of the quadrants into further quadrants and recording the count of 1-bits for each quadrant until all quadrants comprise a pure-1 quadrant or a pure-0 quadrant to form a basic tree structure. |
FILED | Thursday, September 20, 2001 |
APPL NO | 09/957637 |
ART UNIT | 2161 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941355 | Donaghey et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | BBNT Solutions LLC (Cambridge, Massachusetts) |
INVENTOR(S) | Robert J. Donaghey (Lexington, Massachusetts); Sandra E. Carielli (Somerville, Massachusetts); Pamela Helinek (Framingham, Massachusetts) |
ABSTRACT | A method ensures that a set of anonymous peer devices (110) and anonymous policy servers (120) in a system (100) are apprised of all current versions of a policy so that they can quickly implement a version of the policy as it becomes active. The method includes determining whether new versions or a newly active version of a policy exists and generating a message containing the newly received or newly active policy version(s). The method also includes transferring the message to the peer devices (110), the transfer being initiated by either the sender or the receiver. |
FILED | Friday, September 08, 2000 |
APPL NO | 09/658207 |
ART UNIT | 2141 — Graphical User Interface and Document Processing |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/220 |
VIEW PATENT | @ USPTO: Full Text PDF |
06941424 — System, method, and computer program product for high speed DMA-based backplane messaging
US 06941424 | Bade et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Paul R. Bade (Ellicott City, Maryland); Steven A. Kahn (Rockville, Maryland); David M. Verven (Columbia, Maryland) |
ABSTRACT | A system and method of enhanced backplane messaging among a plurality of computer boards communicating over a common bus uses a set of pre-allocated buffers on each computer board to receive messages from other computer boards. Each sending computer board is represented on each remote computer board by a descriptor ring with pointers to pre-allocated buffers on that remote computer board. When a sending computer board has a message to deliver to a remote computer board, the sending computer board uses its DMA controller to transfer the message into the pre-allocated buffers on the remote computer board. The sending computer board also sends a mailbox interrupt to the remote computer board. The remote computer board interrupt handler moves the messages from the descriptor rings to the receiving application(s) via pointer manipulation. Chained DMA transfers are used to eliminate any data transfers by the processor itself across the bus. |
FILED | Friday, July 23, 2004 |
APPL NO | 10/898409 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital processing systems: Memory 711/147 |
VIEW PATENT | @ USPTO: Full Text PDF |
US H2122 | Schepler |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Kenneth L. Schepler (Beavercreek, Ohio) |
ABSTRACT | A diode pumped optical parametric oscillator is disclosed. The apparatus includes a MOPA laser positioned to pump a photorefractive BaTiO3 crystal placed within a ring resonator formed by four mirrors. The interaction of the MOPA laser light incident on the BaTiO3 crystal and with the light reflected within the cavity efficiently converts the MOPA pump beam to a single frequency beam of high beam quality. Once the pump beam exceeds a threshold power level, it interacts with a nonlinear periodically poled lithium niobate crystal received within the ring cavity. The lithium niobate crystal efficiently converts the pump beam to signal and idler beams of different wavelengths, providing an efficient, tunable laser. |
FILED | Tuesday, February 22, 2000 |
APPL NO | 09/507915 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Coherent light generators 372/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
US H2123 | Mollenhauer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | David H. Mollenhauer (Beavercreek, Ohio); John D. Camping (Huber Heights, Ohio) |
ABSTRACT | A process for producing flat or parabolic mirrors for visible wavelength applications is described and includes the steps of casting onto a substrate of substantially the selected mirror shape a liquid polymer resin in multiple cured layers whereby the last applied layer has the selected mirror shape unaffected by topography flaws in the surface of the substrate. A reflective coating may then be applied to the last applied and cured resin layer. |
FILED | Tuesday, March 25, 2003 |
APPL NO | 10/395961 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Coating processes 427/161 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 06939452 | Foret et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Frantisek Foret (Malden, Massachusetts); Thomas Rejtar (Malden, Massachusetts); Bailin Zhang (Boston, Massachusetts); Barry L. Karger (Newton, Massachusetts) |
ABSTRACT | A sample load and injection device (10) includes sample introduction capillaries (11) attached to a microfluidic device (12). Sample introduction capillaries (11) are connected to sample introduction channels (18). Sample introduction capillaries (18) are connected to separation channels (20) at connection points (21). At a defined distance along the separation channels (20), auxilliary channels (23) originate at connection points (24). The sample load and injection device includes cover plate (28) which has connecting channels (26, 32). Connecting channel (26) is associated with ends (24) of sample introduction channels (18). Connecting channel (32) is associated with ends (20). |
FILED | Thursday, January 18, 2001 |
APPL NO | 10/181503 |
ART UNIT | 1753 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Chemistry: Electrical and wave energy 24/458 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939533 | Contag et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Portola Valley, California) |
ABSTRACT | Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen. |
FILED | Wednesday, July 24, 2002 |
APPL NO | 10/205218 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939544 | Horwitz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
INVENTOR(S) | Gregory A. Horwitz (Calabasas, California); Xun Zhang (Malden, Massachusetts); Shlomo Melmed (Los Angeles, California) |
ABSTRACT | Disclosed are isolated antibodies that specifically bind a murine pituitary tumor transforming gene carboxy-terminal (PTTG-C) peptide. The inventive antibodies are useful in assays to determine levels of PTTG proteins or PTTG-C peptides present in a given sample (e.g., tissue samples, biological fluids, Western blots). The antibodies can also be used to purify PTTG proteins or PTTG-C peptides from crude cell extracts and the like. The antibodies are also considered therapeutically useful to counteract and/or supplement the biological effect of PTTG proteins in vivo. |
FILED | Monday, September 30, 2002 |
APPL NO | 10/262252 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/141.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939547 | Aoki et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Yoshiyasu Aoki (Bethesda, Maryland); Giovanna Tosato (Bethesda, Maryland) |
ABSTRACT | A specific binding agent is provided, wherein the specific binding agent specifically binds Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin-6 (vIL-6), and the specific binding agent neutralizes an activity of vIL-6. In one embodiment, the specific binding agent is an antibody. Methods are provided for using a specific binding agent that binds vIL-6, and neutralizes a biological activity of vIL-6. Methods of treatment for a KSHV-associated disorder are also provided. Methods for diagnosing a KSHV-associated disorder are provided, as are kits that include a specific binding agent of the invention. A method is also provided for testing an agent for effectiveness in treating a KSHV-associated disorder. The method includes incubating the agent with a cell free system comprising a vIL-6 receptor component and vIL-6, and comparing the binding of vIL-6 and the receptor component in the presence of the agent to binding of vIL-6 to the receptor component in the absence of the agent. A decrease in the binding of vIL-6 to the receptor component in the presence of the agent indicates that the agent is effective for treating the KSHV-associated disorder. |
FILED | Tuesday, July 31, 2001 |
APPL NO | 10/333121 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/229.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939561 | Kwon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Glen S. Kwon (Waunakee, Wisconsin); John Samuel (Edmonton, Canada); Afsaneh Lavasanifar (Edmonton, Canada) |
ABSTRACT | Provided are methods and compositions for reducing the toxicity of certain hydrophobic therapeutic agents, especially polyene antibiotics, in particular, Amphotericin B (AmB), and therapeutics such as paclitaxel, tamoxifen, an acylated prodrug or an acylated cis-platin, by incorporating these agents within micelles comprising an amphiphilic block-forming copolymer. Where the polyene is amphotericin B, desirably the spacer is an alkyl molecule of aabout 2 to about 8 carbon atoms, desirably 6 carbon atoms, and the core is an N-alkyl molecule of about 8 to about 28 carbon atoms, desirably 12 to 22 carbon atoms, advantageously, 12 to 18 carbon atoms, and as specifically embodied, 18 carbon atoms (stearate moiety). For the formulation of a larger polyene, the spacer and core are proportionately larger than those for amphotericin B. As specifically exemplified herein, the polymer backbone is a PEO of about 270 units with about 10-30 core-forming PLAA subunits, and advantageously about 14-24. Desirably the stearate moiety has a substitution level on the copolymer from about 35 percent to about 70 percent. |
FILED | Friday, June 28, 2002 |
APPL NO | 10/187317 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/484 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939691 | Khosla et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Chaitan Khosla (Palo Alto, California); Blaine Pfeifer (Palo Alto, California) |
ABSTRACT | The use of enzymes that catalyze the production of starter and extender units for polyketides in E. coli and Streptomyces is described; these enzymes include malonyl CoA decarboxylase (MatA), malonyl CoA synthetase (MatB), and a malonate transporter (MatC) as well as proprionyl CoA carboxylase (pcc). The matBC gene from Streptomyces coelicolor, the matABC genes from Rhizobium trifoli, and the pccB and accA2 from Streptomyces coelicolor are useful in specific embodiments of the claimed invention. These enzymes may be used to enhance the yield of polyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. coli in the presence of a phosphopantetheinyl transferase, such as sfp from Bacillus subtilis. This achievement permits a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling. |
FILED | Friday, October 13, 2000 |
APPL NO | 09/687855 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/76 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939712 | Bahramian et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Impedagen, LLC (Seattle, Washington) |
INVENTOR(S) | Mohammad B. Bahramian (Branford, Connecticut); Helmut Zarbl (Snoqualmie, Washington) |
ABSTRACT | The invention provides compositions and methods for muting expression of an endogenous gene in an animal cell, the muting resulting from providing a transgene to a cell. Expression of which transgene is undetectable. The transgene comprises the muting nucleic acid, which is substantially homologous to a portion of the endogenous gene. The portion of the endogenous gene provided on the transgene can be from the 5′-untranscribed end, from the 3′ untranscribed end, from an exon or an intron in the coding portion, or from a portion that overlaps any of these portions. Methods are provided for obtaining muting nucleic acid, and for screening for molecules that can mute the gene, and for molecules that can alleviate muting of the gene. |
FILED | Monday, December 27, 1999 |
APPL NO | 09/472558 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/463 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939716 | Heinecke |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Jay W. Heinecke (Seattle, Washington) |
ABSTRACT | The disclosure describes a method for detecting conditions indicative of sepsis. In one embodiment of the invention, an increase in the level of 3-chlorotyrosine or 3-bromotyrosine from the normal level in a sample of body fluid or tissue is indicative of early sepsis or infection. In another embodiment of the invention, the level of 3-chlorotyrosine or 3-bromotyrosine is measured or monitored to determine the response to therapeutic treatment of the infective condition in which a reduction in the level that existed prior to the treatment is an early sign or indication that the treatment is working in vivo. In a preferred embodiment, the method of the invention is illustrated in a clinically relevant mouse model of sepsis. |
FILED | Thursday, August 22, 2002 |
APPL NO | 10/225700 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/89 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939848 | Steitz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Thomas A. Steitz (Branford, Connecticut); Peter B. Moore (North Haven, Connecticut); Nenad Ban (Zürich, Switzerland); Poul Nissen (Aarhus, Denmark); Jeffrey Hansen (New Haven, Connecticut) |
ABSTRACT | The present invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as the crystals produced by such methods. The x-ray diffraction patterns of the crystals provided by the present invention are of sufficiently high resolution for determining the three-dimensional structure of ribosomes and ribosomal subunits, for identifying ligand binding sites on ribosomes and ribosomal subunits, and for molecular modeling of ligands which interact with ribosomes and ribosomal subunits. The present invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties. Thus, the methods of the present invention may be used to produce ligands which are designed to kill or inhibit any specific target organism(s). |
FILED | Monday, March 17, 2003 |
APPL NO | 10/391491 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939850 | Horvitz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | H. Robert Horvitz (Auburndale, Massachusetts); Junying Yuan (Newton, Massachusetts); Shai Shaham (Cambridge, Massachusetts) |
ABSTRACT | Described herein is the discovery that human interleukin-1β convertase (ICE) is structurally similar to the protein encoded by the C. elegans cell death gene, ced-3. Comparative and mutational analyses of the two proteins, together with previous observations, suggest that the Ced-3 protein may be a cysteine protease like ICE and that ICE may be a human equivalent of the nematode cell death gene. Another mammalian protein, the murine NEDD-2 protein, was also found to be similar to Ced-3. The NEDD-2 gene is implicated in the development of the murine central nervous system. On the basis of these findings, novel drugs for enhancing or inhibiting the activity of ICE, ced-3, or related genes are provided. Such drugs may be useful for treating inflammatory diseases and/or diseases characterized by cell deaths, as well as cancers, autoimmune disorders, infections, and hair growth and hair loss. Furthermore, such drugs may be useful for controlling pests, parasites and genetically engineered organisms. Furthermore, novel inhibitors of the activity of ced-3, ICE and related genes are described which comprise portions of the genes or their encoded products. |
FILED | Friday, June 22, 2001 |
APPL NO | 09/888243 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939883 | Tucci et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Neurocrine Biosciences, Inc. (San Diego, California) |
INVENTOR(S) | Fabio Tucci (San Diego, California); Patrick J. Connors (San Diego, California); Yun-Fei Zhu (San Diego, California); Chen Chen (San Diego, California) |
ABSTRACT | GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, R1, R2, R3a, R3b, R4, R5, R6, R7 and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof. |
FILED | Friday, August 02, 2002 |
APPL NO | 10/211978 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/336 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939948 | Ferrone et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York); Sloan Kettering Institute for Cancer Research (New York, New York) |
INVENTOR(S) | Soldano Ferrone (Buffalo, New York); Chun-Yen Tsao (Grand Island, New York); Xinhui Wang (Williamsville, New York); Wei Luo (Getzville, New York); Nai-Kong V. Cheung (Purchase, New York) |
ABSTRACT | The present invention provides peptide mimics for GD2 ganglioside. The peptide mimics were identified by panning phage display peptide libraries with an anti-GD2 monoclonal antibody. The identified peptide mimics can be used as immunogens for cancer therapy such as for melanoma and neuroblastoma. |
FILED | Monday, March 24, 2003 |
APPL NO | 10/395434 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939952 | Zhao |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Zhizhuang Zhao (Franklin, Tennessee) |
ABSTRACT | Isolated and purified proteins and nucleic acids including a novel member of the immunoglobulin super-family characterized as having SHP-2 binding activity and cell signaling activity and called protein zero related or PZR, and cDNA encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to PZR, and methods of producing the same, are also disclosed. PZR is characterized as having SHP-2 binding activity and cell signaling activity and thus, therapeutic methods involving these activities are also disclosed. |
FILED | Monday, March 11, 2002 |
APPL NO | 10/095131 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939955 | Rameshwar |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey) |
INVENTOR(S) | Pranela Rameshwar (Maplewood, New Jersey) |
ABSTRACT | Bone marrow (BM) is the major organ where immune cells are derived. Homeostasis in the BM is maintained by inter- and intra-cellular interactions by the various subsets of BM cells. The present invention discloses the cloning of a new cDNA from stimulated BM stromal cells that was retrieved with a probe specific for the neurokinin-1 (NK-1) receptor. The cloned cDNA was designated ‘Hematopoietic Growth Factor Inducible Neurokinin-1 type’ (HGFIN) gene based on its expression in differentiated hematopoietic cells. Hence, the present invention provides a novel gene, HGFIN, which encodes a protein receptor that is involved in the regulation of hematopoietic proliferation and differentiation. The protein of the present invention may be involved as a central mediator of white blood cell, progenitor, differentiation, and therefore, may be useful in the prevention and treatment of lymphoproliferative syndromes such as B-cell related maladies, including but not limited to acute and chronic myeloid and lymphocytic leukemia as well as the B-cell subtype of Hodgkin's and non-Hodgkin's lymphomas. |
FILED | Saturday, October 20, 2001 |
APPL NO | 10/039272 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939973 | Rebek, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Julius Rebek, Jr. (La Jolla, California); Kent E. Pryor (San Diego, California) |
ABSTRACT | The present invention provides novel glycoluril derivatives for use as core molecules in combinatorial chemistry. Core molecules of the present invention can contain from one to six building blocks. Preferred building blocks are substituted amine radicals. Combinatorial libraries containing such core molecules are also provided. |
FILED | Tuesday, February 09, 1999 |
APPL NO | 09/246468 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 548/303.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939977 | Makriyannis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The University of Connecticut (Farmington, Connecticut) |
INVENTOR(S) | Alexandros Makriyannis (Mystic, Connecticut); Dai Lu (Storrs, Connecticut); Atmaram Khanolkar (Coventry, Rhode Island) |
ABSTRACT | Disclosed are novel compounds represented by the following structural formula: R-X-Y; and physiologically acceptable salts thereof. R is a tricyclic core of a cannabinoid or substituted cannabinoid. X is a covalent bond, —CH2— or —CHR1—, wherein R1 a C1 to C3 substituted or unsubstituted alkyl group. Y is a heterocyclic ring, a substituted heterocyclic ring, a carbocyclic ring, a substituted carbocyclic ring, a fused bicyclic ring system, a substituted fused bicyclic ring system, a bridged bicyclic ring system, a substituted bridged bicyclic ring system, a bridged tricyclic ring system or a substituted bridged tricyclic ring system. Also disclosed is a method of stimulating a CB1 and/or CB2 receptor in a subject. The method comprises administering to the subject a therapeutically effective amount of R-X-Y. |
FILED | Wednesday, December 04, 2002 |
APPL NO | 10/309686 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 549/280 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939978 | Chang et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Ching-jer Chang (Lafayette, Indiana); Xiao-jie Tong (Palisades Park, New Jersey) |
ABSTRACT | A high yield, economical process for purifying taxanes from yew biomass is disclosed. The process does not require initial liquid:liquid portioning of the crude extract to separate highly polar substances. The organic solvent extract of the biomass is adsorbed onto and selectively desorbed from an adsorption resin to provide a taxane enriched eluate. Substantially pure individual taxanes may be further isolated from the eluate by hydrophobic-interaction chromatography. |
FILED | Wednesday, July 10, 2002 |
APPL NO | 10/193664 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 549/510 |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE38793 | Rinehart et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Kenneth L. Rinehart (Urbana, Illinois); Nancy L. Gallagher (Vernon Hills, Illinois); Robert A. Warwick (Urbana, Illinois) |
ABSTRACT | The present invention is directed to the isolation and bioactive characterization of compounds isolated from the clam Spisula polynyma. These compounds include three sphingoid-type bases, spisulosines 285, 299 and 313 (1-3), each of which shows unique cytotoxicity against L1210 murine lymphocytic leukemia cells. In addition, sphingosine (also referred to as 4-sphingenine or octadeca-4-shpingenine, 4) and two related compounds, nonadeca-4-sphingenine (a one carbon longer homolog, 5) and sphinga-4,10-diene (a dehydrosphingosine deravitive, 6) were also obtained, These compounds also contribute to the cytotoxicity of the Spisula polynyma extracts, but did not cause the morphology changes observed with compounds 1-3. |
FILED | Wednesday, August 14, 2002 |
APPL NO | 10/219050 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Organic compounds 564/360 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 06938488 | Diaz et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Aaron A. Diaz (West Richland, Washington); Brion J. Burghard (West Richland, Washington); James R. Skorpik (Kennewick, Washington); Richard A. Pappas (Richland, Washington); O. Dennis Mullen (West Richland, Washington); Todd J. Samuel (Pasco, Washington); Larry D. Reid (Benton City, Washington); Joe C. Harris (Kennewick, Washington); Juan D. Valencia (Richland, Washington); Jonathan T. Smalley (Battle Ground, Washington); Chester L. Shepard (West Richland, Washington); Theodore T. Taylor (Richland, Washington) |
ABSTRACT | An ultrasound inspection apparatus particularly adapted to examine containers (sealed or unsealed) containing a liquid or solid bulk material. The apparatus has an overall configuration of a hand held pistol with a front transducer contact surface that is positioned against a front wall of the container. An ultrasound pulse is transmitted from the apparatus to be reflected from a back wall of a container being investigated. The received echo pulse is converted to a digital waveform. The waveform is analyzed relative to temperature, travel distance of the pulse(s), and time of travel to ascertain characteristics of the liquid or other materials and to provide identification of the same. |
FILED | Wednesday, August 21, 2002 |
APPL NO | 10/225910 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/597 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06938503 | Clark et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Don T. Clark (Idaho Falls, Idaho); Eugene E. Erickson (Pocatello, Idaho); William L. Casper (Rigby, Idaho); David M. Everett (Shelley, Idaho); Joel M. Hubbell (Idaho Falls, Idaho); James B. Sisson (Idaho Falls, Idaho) |
ABSTRACT | A suction lysimeter for sampling subsurface liquids includes a lysimeter casing having a drive portion, a reservoir portion, and a tip portion, the tip portion including a membrane through which subsurface liquids may be sampled; a fluid conduit coupled in fluid flowing relation relative to the membrane, and which in operation facilitates the delivery of the sampled subsurface liquids from the membrane to the reservoir portion; and a plurality of tubes coupled in fluid flowing relation relative to the reservoir portion, the tubes in operation facilitating delivery of the sampled subsurface liquids from the reservoir portion for testing. A method of sampling subsurface liquids comprises using this lysimeter. |
FILED | Monday, October 25, 2004 |
APPL NO | 10/973710 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/863.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939130 | Abbasi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Gas Technology Institute (Des Plaines, Illinois) |
INVENTOR(S) | Hamid A. Abbasi (Naperville, Illinois); William J. Hobson, Jr. (Roscoe, Illinois); David M. Rue (Chicago, Illinois); Valeriy Smirnov (Loves Park, Illinois) |
ABSTRACT | A combustion apparatus comprising a pre-combustor stage and a primary combustion stage, the pre-combustor stage having two co-axial cylinders, one for oxidant and one for fuel gas, in which the fuel gas is preheated and the primary combustion stage having rectangular co-axial passages through which fuel and oxidant are admitted into a refractory burner block. Both passages converge in the vertical plane and diverge in the horizontal plane. The passage through the refractory burner block also has a rectangular profile and diverges in the horizontal plane. The outlets to the primary combustion stage are recessed in the refractory burner block at a distance which may be varied. |
FILED | Friday, December 05, 2003 |
APPL NO | 10/729810 |
ART UNIT | 3749 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Combustion 431/351 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939506 | Qian et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
INVENTOR(S) | Jiang Qian (Los Alamos, New Mexico); Yusheng Zhao (Los Alamos, New Mexico) |
ABSTRACT | Fully dense, diamond-silicon carbide composites are prepared from ball-milled microcrystalline diamond/amorphous silicon powder mixture. The ball-milled powder is sintered (P=5-8 GPa, T=1400K-2300K) to form composites having high fracture toughness. A composite made at 5 GPa/1673K had a measured fracture toughness of 12 MPa·m1/2. By contrast, liquid infiltration of silicon into diamond powder at 5 GPa/1673K produces a composite with higher hardness but lower fracture toughness. X-ray diffraction patterns and Raman spectra indicate that amorphous silicon is partially transformed into nanocrystalline silicon at 5 GPa/873K, and nanocrystalline silicon carbide forms at higher temperatures. |
FILED | Friday, May 30, 2003 |
APPL NO | 10/448672 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/682 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939524 | Piskoti et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Charles R. Piskoti (Fenton, Michigan); Alex K. Zettl (Kensington, California); Marvin L. Cohen (Piedmont, California); Michel Cote (Cambridge, United Kingdom); Jeffrey C. Grossman (Berkeley, California); Steven G. Louie (Berkeley, California) |
ABSTRACT | A solid phase or form of carbon is based on fullerenes with thirty six carbon atoms (C36). The C36 structure with D6h symmetry is one of the two most energetically favorable, and is conducive to forming a periodic system. The lowest energy crystal is a highly bonded network of hexagonal planes of C36 subunits with AB stacking. The C36 solid is not a purely van der Waals solid, but has covalent-like bonding, leading to a solid with enhanced structural rigidity. The solid C36 material is made by synthesizing and selecting out C36 fullerenes in relatively large quantities. A C36 rich fullerene soot is produced in a helium environment arc discharge chamber by operating at an optimum helium pressure (400 torr). The C36 is separated from the soot by a two step process. The soot is first treated with a first solvent, e.g. toluene, to remove the higher order fullerenes but leave the C36. The soot is then treated with a second solvent, e.g. pyridine, which is more polarizable than the first solvent used for the larger fullerenes. The second solvent extracts the C36 from the soot. Thin films and powders can then be produced from the extracted C36. Other materials are based on C36 fullerenes, providing for different properties. |
FILED | Friday, March 03, 2000 |
APPL NO | 09/518989 |
ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/445.B00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939554 | McDonald et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Michigan Biotechnology Institute (Lansing, Michigan) |
INVENTOR(S) | William F. McDonald (Utica, Ohio); Zhi-Heng Huang (Walnut Creek, California); Stacy C. Wright (Columbus, Georgia) |
ABSTRACT | A polymeric composition having antimicrobial properties and a process for rendering the surface of a substrate antimicrobial are disclosed. The composition comprises a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along a backbone forming the polymer, (ii) an antimicrobial agent selected from quaternary ammonium compounds, gentian violet compounds, substituted or unsubstituted phenols, biguanide compounds, iodine compounds, and mixtures thereof, and (iii) a crosslinking agent containing functional groups capable of reacting with the amino groups. In one embodiment, the polymer is a polyamide formed from a maleic anhydride or maleic acid ester monomer and alkylamines thereby producing a polyamide having amino substituted alkyl chains on one side of the polyamide backbone; the crosslinking agent is a phosphine having the general formula (A)3P wherein A is hydroxyalkyl; and the antimicrobial agent is chlorhexidine, dimethylchlorophenol, cetyl pyridinium chloride, gentian violet, triclosan, thymol, iodine, and mixtures thereof. |
FILED | Tuesday, February 05, 2002 |
APPL NO | 10/068054 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/405 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939876 | Dewey et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | Stephen L. Dewey (Manorville, New York); Jonathan D. Brodie (Cos Cob, Connecticut); Charles R. Ashby, Jr. (Miller Place, New York) |
ABSTRACT | The present invention provides a composition for treating pain. The composition includes a pharmaceutically acceptable analgesic and a GABAergic agent, such as gamma vinyl GABA, effective in reducing or eliminating the addictive liability of the analgesic. The invention also includes a method for reducing or eliminating the addictive |
FILED | Thursday, April 18, 2002 |
APPL NO | 10/124660 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/282 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940715 | Beihoff et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Rockwell Automation Technologies, Inc. (Mayfield Heights, Ohio) |
INVENTOR(S) | Bruce C. Beihoff (Wauwatosa, Wisconsin); Lawrence D. Radosevich (Muskego, Wisconsin); Andreas A. Meyer (Richmond Heights, Ohio); Neil Gollhardt (Fox Point, Wisconsin); Daniel G. Kannenberg (Waukesha, Wisconsin) |
ABSTRACT | A support may receive one or more power electronic circuits. The support may aid in removing heat from the circuits through fluid circulating through the support. The support, in conjunction with other packaging features may form a shield from both external EMI/RFI and from interference generated by operation of the power electronic circuits. Features may be provided to permit and enhance connection of the circuitry to external circuitry, such as improved terminal configurations. Modular units may be assembled that may be coupled to electronic circuitry via plug-in arrangements or through interface with a backplane or similar mounting and interconnecting structures. |
FILED | Tuesday, September 16, 2003 |
APPL NO | 10/663171 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/689 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941227 | Goloshubin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Gennady M. Goloshubin (Sugar Land, Texas); Valeri A. Korneev (Lafayette, California) |
ABSTRACT | A method for identifying, imaging and monitoring dry or fluid-saturated underground reservoirs using seismic waves reflected from target porous or fractured layers is set forth. Seismic imaging the porous or fractured layer occurs by low pass filtering of the windowed reflections from the target porous or fractured layers leaving frequencies below low-most corner (or full width at half maximum) of a recorded frequency spectra. Additionally, the ratio of image amplitudes is shown to be approximately proportional to reservoir permeability, viscosity of fluid, and the fluid saturation of the porous or fractured layers. |
FILED | Tuesday, April 30, 2002 |
APPL NO | 10/137201 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/17 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 06939604 | Guyot-Sionnest et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Arch Development Corporation (Chicago, Illinois) |
INVENTOR(S) | Philippe Guyot-Sionnest (Chicago, Illinois); Moonsub Shim (Mountain View, California); Conjun Wang (Chicago, Illinois) |
ABSTRACT | A particle, includes a semiconductor nanocrystal. The nanocrystal is doped. |
FILED | Thursday, October 19, 2000 |
APPL NO | 09/694090 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Stock material or miscellaneous articles 428/323 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939625 | Marks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Nôrthwestern University (Evanston, Illinois) |
INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Qinglan Huang (Skokie, Illinois); Ji Cui (Acton, Massachusetts); Jonathan Veinot (Palatine, Illinois) |
ABSTRACT | New organic light-emitting diodes and related electroluminescent devices and methods for fabrication, using siloxane self-assembly techniques. |
FILED | Friday, March 15, 2002 |
APPL NO | 10/099131 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Stock material or miscellaneous articles 428/690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939691 | Khosla et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Chaitan Khosla (Palo Alto, California); Blaine Pfeifer (Palo Alto, California) |
ABSTRACT | The use of enzymes that catalyze the production of starter and extender units for polyketides in E. coli and Streptomyces is described; these enzymes include malonyl CoA decarboxylase (MatA), malonyl CoA synthetase (MatB), and a malonate transporter (MatC) as well as proprionyl CoA carboxylase (pcc). The matBC gene from Streptomyces coelicolor, the matABC genes from Rhizobium trifoli, and the pccB and accA2 from Streptomyces coelicolor are useful in specific embodiments of the claimed invention. These enzymes may be used to enhance the yield of polyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. coli in the presence of a phosphopantetheinyl transferase, such as sfp from Bacillus subtilis. This achievement permits a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling. |
FILED | Friday, October 13, 2000 |
APPL NO | 09/687855 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/76 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939778 | Harpster et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Timothy J. Harpster (Ann Arbor, Michigan); Khalil Najafi (Ann Arbor, Michigan) |
ABSTRACT | Bonding methods and articles produced thereby are provided wherein an insulator, such as glass, is bonded to a solder with the assistance of an electric field. |
FILED | Wednesday, April 16, 2003 |
APPL NO | 10/417299 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/406 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939945 | Bertozzi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Carolyn R. Bertozzi (Albany, California); Lisa A. Marcaurelle (Berkeley, California); Elena C. Rodriguez (Berkeley, California) |
ABSTRACT | The invention provides methods and compositions useful for making synthetic peptide conjugates. In one embodiment, the invention provides compositions comprising the structure: wherein R is selected from lower substituted or unsubstituted alkyl, O, NH and S and P is an amine protection group. In more particular embodiments, the compositions comprise α-amine protected 4,5-dehydroleucine or α-amine protected (2S)-aminolevulinic acid and/or P is F-moc. These compounds may be incorporated into peptides, for example, peptides comprising a substituted or unsubstituted (2S)-aminolevulinic acid residue, such as (2S)-aminolevulinic acid residue is substituted with an O- or N-linked glycoconjugate, or a detectable label. |
FILED | Thursday, October 10, 2002 |
APPL NO | 10/268813 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939982 | Hoveyda et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
INVENTOR(S) | Amir H. Hoveyda (Belmont, Massachusetts); Joshua Van Veldhuizen (Watertown, Massachusetts); Steven B. Garber (Brighton, Massachusetts); Jason S. Kingsbury (Brookline, Massachusetts) |
ABSTRACT | The present invention relates to chiral metal catalysts for stereoselective olefin metathesis reactions, which are recyclable and reusable in such metathesis reactions. The chiral metal-based metathesis catalysts of the invention comprise multidentate optically active or racemic chiral ligands that enable their use in asymmetric synthetic processes, such as for example, in ring-opening and ring-closing metathesis reactions (ROM and RCM, respectively) of alkenes. The catalysts of the invention are organometallic complexes of multivalent metals comprising one or more chiral bidentate ligands that exhibit superior reactivity and stereoselectivity properties. The present invention also provides methods of making such catalysts and methods for utilizing them in catalyzing stereoselective olefin metathesis reactions to provide asymmetric products in relatively high enantiomeric or stereoisomeric excess. |
FILED | Monday, May 12, 2003 |
APPL NO | 10/435777 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 556/21 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941039 | Gaylord et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Thomas K Gaylord (Atlanta, Georgia); Gregory D. VanWiggeren (Los Gatos, California); Donald D. Davis (Duluth, Georgia); Elias N. Glytsis (Dunwoody, Georgia); Emmanuel Anemogiannis (Atlanta, Georgia) |
ABSTRACT | The present invention relates to a type of optical fiber grating having an azimuthal refractive-index perturbation. The optical fiber includes a fiber grating that has a plurality of grating elements formed therein. At least one of the grating elements has a spatially varying index of refraction that varies azimuthally about the centerline of the optical fiber. The fiber grating acts as a band-stop optical spectral filter. In addition, since fiber-cladding modes are weakly-guided modes, their power can be easily dissipated by scattering, bending, stretching, and/or rotating the optical fiber. Multiple configurations of these gratings within an optical fiber are given. Devices are presented which can dynamically attenuate, tune, switch, or modulate the wavelength spectral characteristics of an optical signal. |
FILED | Thursday, July 08, 2004 |
APPL NO | 10/886800 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06941303 | Perrizo |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
INVENTOR(S) | William K. Perrizo (Fargo, North Dakota) |
ABSTRACT | A system and method to take data, which is in the form of an n-dimensional array of binary data where the binary data is comprised of bits that are identified by a bit position within the n-dimensional array, and create one file for each bit position of the binary data while maintaining the bit position identification and to store the bit with the corresponding bit position identification from the binary data within the created filed. Once this bit-sequential format of the data is achieved, the formatted data is structured into a tree format that is data-mining-ready. The formatted data is structured by dividing each of the files containing the binary data into quadrants according to the bit position identification and recording the count of 1-bits for each quadrant on a first level. Then, recursively dividing each of the quadrants into further quadrants and recording the count of 1-bits for each quadrant until all quadrants comprise a pure-1 quadrant or a pure-0 quadrant to form a basic tree structure. |
FILED | Thursday, September 20, 2001 |
APPL NO | 09/957637 |
ART UNIT | 2161 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 06938853 | Pines et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Darryll J. Pines (Clarksville, Maryland); Felipe A. Bohorquez (College Park, Maryland); Jayant Sirohi (Greenbelt, Maryland) |
ABSTRACT | A biomimetic pitching and flapping mechanism including a support member, at least two blade joints for holding blades and operatively connected to the support member. An outer shaft member is concentric with the support member, and an inner shaft member is concentric with the outer shaft member. The mechanism allows the blades of a small-scale rotor to be actuated in the flap and pitch degrees of freedom. The pitching and the flapping are completely independent from and uncoupled to each other. As such, the rotor can independently flap, or independently pitch, or flap and pitch simultaneously with different amplitudes and/or frequencies. The mechanism can also be used in a non-rotary wing configuration, such as an ornithopter, in which case the rotational degree of freedom would be suppressed. |
FILED | Friday, March 14, 2003 |
APPL NO | 10/387494 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/11 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939073 | Ahmed et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Rafiq Ahmed (Madison, Alabama); Robert J. Wingate (Huntsville, Alabama) |
ABSTRACT | In the aerospace field spacecraft components are held together by separation systems until a specific time when they must be separated or deployed. Customarily a threaded joining bolt engages one of the components to be joined, and a threaded nut is placed on that bolt against the other component so they can be drawn together by a releasable locking assembly. The releasable locking assembly herein includes a plunger having one end coupled to one end of a plunger bolt. The other end is flanged to abut and compress a coil spring when the plunger is advanced toward the interface plane between the two components. When the plunger is so advanced toward the interface plane, the end of the plunger bolt can be connected to the joining bolt. Thus during retraction the joining bolt is drawn to one side of the interface plane by the force of the expanding spring. |
FILED | Tuesday, August 26, 2003 |
APPL NO | 10/652083 |
ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Joints and connections 43/24 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939610 | Kaul |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Raj K. Kaul (Hampton Cove, Alabama) |
ABSTRACT | To protect spacecraft and their contents from excessive heat thermal protection systems are essential. For such thermal protection, metal coatings, ceramic materials, ablative materials, and various matrix materials have all been tried, but none have been found entirely satisfactory. The basis for this thermal protection system is the fact that the heat required to melt a substance is 80 to 100 times larger than the heat required to raise its temperature one degree. This led to the use herein of solid-liquid phase change materials. Unlike conventional heat storage materials, when phase change materials reach the temperature at which they change phase they absorb large amounts of heat without getting hotter. By this invention, then, a coating composition is provided for application to substrates subjected to temperatures above 100° F. The coating composition includes a phase change material. |
FILED | Wednesday, July 31, 2002 |
APPL NO | 10/212564 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Stock material or miscellaneous articles 428/403 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939940 | Dingemans et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Theodorous J. Dingemans (Hampton, Virginia); Erik S. Weiser (Newport News, Virginia); Terry L. St. Clair (Poquoson, Virginia) |
ABSTRACT | Main chain thermotropic liquid crystal esters, ester-imides, and ester-amides were prepared from AA, BB, and AB type monomeric materials and were end-capped with phenylacetylene, phenylmaleimide, or nadimide reactive end-groups. The resulting reactive end-capped liquid crystal oligomers exhibit a variety of improved and preferred physical properties. The end-capped liquid crystal oligomers are thermotropic and have, preferably, molecular weights in the range of approximately 1000-15,000 grams per mole. The end-capped liquid crystal oligomers have broad liquid crystalline melting ranges and exhibit high melt stability and very low melt viscosities at accessible temperatures. The end-capped liquid crystal oligomers are stable for up to an hour in the melt phase. These properties make the end-capped liquid crystal oligomers highly processable by a variety of melt process shape forming and blending techniques including film extrusion, fiber spinning, reactive injection molding (RIM), resin transfer molding (RTM), resin film injection (RFI), powder molding, pultrusion, injection molding, blow molding, plasma spraying and thermo-forming. Once processed and shaped, the end-capped liquid crystal oligomers were heated to further polymerize and form liquid crystalline thermosets (LCT). The fully cured products are rubbers above their glass transition temperatures. The resulting thermosets display many properties that are superior to their non-end-capped high molecular weight analogs. |
FILED | Friday, January 05, 2001 |
APPL NO | 09/757398 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Synthetic resins or natural rubbers 528/170 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940422 | Bachelder et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Aaron D. Bachelder (Irvine, California); Conrad F. Foster (Los Angeles, California) |
ABSTRACT | An emergency vehicle traffic light preemption system for preemption of traffic lights at an intersection to allow safe passage of emergency vehicles. The system includes a real-time status monitor of an intersection which is relayed to a communications controller for transmission to emergency vehicles as well as to a central dispatch office. The system also provides for audio warnings at an intersection to protect pedestrians who may not be in a position to see visual warnings or for various reasons cannot hear the approach of emergency vehicles. A transponder mounted on an emergency vehicle provides autonomous control so the vehicle operator can attend to getting to an emergency and not be concerned with the operation of the system. Activation of a Code 3 situation provides communications with each intersection being approached by an emergency vehicle and indicates whether the intersection is preempted or if there is any conflict with other approaching emergency vehicles. On-board diagnostics handle various information including heading, speed, and acceleration sent to a communications controller which is transmitted to an intersection and which also simultaneously receives information regarding the status of an intersection. |
FILED | Friday, August 15, 2003 |
APPL NO | 10/642435 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Communications: Electrical 340/906 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 06939481 | Srivastava et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Alok Mani Srivastava (Niskayuna, New York); Holly Ann Comanzo (Niskayuna, New York); Thomas Francis McNulty (Ballston Lake, New York) |
ABSTRACT | There is provided white light illumination system including a radiation source, a first luminescent material having a peak emission wavelength of about 575 to about 620 nm, a second luminescent material having a peak emission wavelength of about 495 to about 550 nm, which is different from the first luminescent material and a third luminescent material having a peak emission wavelength of about 420 to about 480 nm, which is different from the first and second luminescent materials. The LED may be a UV LED and the luminescent materials may be a blend of three or four phosphors. The first phosphor may be an orange emitting Eu2+, Mn2+ activated strontium pyrophosphate, Sr2P2O7:Eu2+, Mn2+. The second phosphor may be a blue-green emitting Eu2+ activated barium silicate, (Ba,Sr,Ca)2SiO4:Eu2+. The third phosphor may be a blue emitting SECA phosphor, (Sr,Ba,Ca)5(PO4)3Cl:Eu2+. Optionally, the fourth phosphor may be a red emitting Mn4+ activated magnesium fluorogermanate, 3.5MgO*0.5MgF2*GeO2:Mn4+. A human observer perceives the combination of the orange, blue-green, blue and/or red phosphor emissions as white light. |
FILED | Friday, July 11, 2003 |
APPL NO | 10/617028 |
ART UNIT | 1755 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Compositions 252/301.4R0 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939576 | Deshpande et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | nGimat Co. (Atlanta, Georgia) |
INVENTOR(S) | Girish Deshpande (Atlanta, Georgia); Andrew Tye Hunt (Atlanta, Georgia); Subramaniam Shanmugham (Duluth, Georgia); Eric J. Yurtkuran (Atlanta, Georgia); Todd Polley (Atlanta, Georgia); Miodrag Oljara (Avondale Est., Georgia); Tzyy-Jiuan Jan Hwang (Alpharetta, Georgia); Aimee Poda (Atlanta, Georgia); George Neuman (Ann Arbor, Michigan) |
ABSTRACT | Coatings, particularly thin films, of polymeric material are produced in accordance with the invention by applying a finely divided aerosol of polymer solution to a substrate and substantially simultaneously applying an energy source to the applied solution to apply the solution. In cases where the polymer is cross-linking, the energy source assists in cross-linking of the polymer. The preferred energy source is a flame that may optionally or desirably deposit material along with the polymer spray. One particular aspect of the invention is directed to production of polyimide films. In accordance with another aspect of the invention, the co-deposition process is used to provide thin polysiloxane coatings on glass and other substrates. |
FILED | Wednesday, June 27, 2001 |
APPL NO | 10/311785 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Coating processes 427/223 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06940599 | Hovde |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Southwest Sciences Incorporated (Santa Fe, New Mexico) |
INVENTOR(S) | David Christian Hovde (Cincinnati, Ohio) |
ABSTRACT | A spectrometer and spectrometry method comprising modulating a light source with a carrier waveform multiplied by an envelope function, directing light from the light source through a sample region and to a photodetector, and demodulating current from the photodetector at a reference frequency. Also a method for computing a modulation waveform comprising specifying a target detection efficiency in a Fourier space, computing a response of a waveform that comprises a carrier wave multiplied by an envelope function, and modifying the envelope function using nonlinear optimization means to minimize a difference between the computed response and a predetermined target gain spectrum. |
FILED | Monday, February 10, 2003 |
APPL NO | 10/364777 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/432 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 06939864 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Timothy Robert Johnson (Noblesville, Indiana); Susan Dee Eicher (Lafayette, Indiana); Carrie A. McKee (Wright City, Missouri) |
ABSTRACT | Compositions comprising beta-glucan and ascorbic acid and methods of using the same to improve well-being of animals are provided. The combination of beta-glucan and ascorbic acid exhibit a synergistic effect on the well-being of animals. |
FILED | Tuesday, July 09, 2002 |
APPL NO | 10/192762 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 06939950 | Taylor et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Iowa State University Research Foundation (Ames, Iowa); The United States of America as represented by the Department of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Michael J. Taylor (Corvallis, Oregon); Marcus E. Kehrli, Jr. (Terre Haute, Indiana); Eun-Kyung Lee (Taegu, South Korea); Simon Mwangi (Ames, Iowa) |
ABSTRACT | The invention relates to nucleic acid sequences encoding a bovine tumor necrosis factor receptor-I (TNF-RI). Also within the invention is a soluble bovine TNF-RI, which is a potent inhibitor of bovine tumor necrosis factor-α (TNF-α). The invention demonstrates that soluble bovine TNF-RI has therapeutic value as an inhibitor of TNF in cattle suffering from coliform mastitis or other inflammatory disease. |
FILED | Wednesday, October 03, 2001 |
APPL NO | 09/970532 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 06940599 | Hovde |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Southwest Sciences Incorporated (Santa Fe, New Mexico) |
INVENTOR(S) | David Christian Hovde (Cincinnati, Ohio) |
ABSTRACT | A spectrometer and spectrometry method comprising modulating a light source with a carrier waveform multiplied by an envelope function, directing light from the light source through a sample region and to a photodetector, and demodulating current from the photodetector at a reference frequency. Also a method for computing a modulation waveform comprising specifying a target detection efficiency in a Fourier space, computing a response of a waveform that comprises a carrier wave multiplied by an envelope function, and modifying the envelope function using nonlinear optimization means to minimize a difference between the computed response and a predetermined target gain spectrum. |
FILED | Monday, February 10, 2003 |
APPL NO | 10/364777 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/432 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 06941013 | Drayer |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the National Security Agency (Washington, District of Columbia) |
INVENTOR(S) | Thomas Hudson Drayer (Laurel, Maryland) |
ABSTRACT | Method of image binarization using histogram modeling, which combines spatial resolution expansion with binarization in a single integrated process using a combination of spatial expansion, histogram modeling, classification, and quantization. Each pixel of the input image is expanded into a higher resolution image, and a count of the number of times each distinct gray scale intensity value occurs in the input image is calculated from pixel values of the input image and then modeled with an approximate histogram that is computed as the sum of weighted modeling functions. The input pixel values are then classified using the modeling functions and the results of the pixel classification are used to quantize the high resolution gray scale image to create a binary output image. |
FILED | Monday, April 22, 2002 |
APPL NO | 10/063423 |
ART UNIT | 2625 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/168 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 06939676 | Burke et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Argriculture (Washington, District of Columbia) |
INVENTOR(S) | John J. Burke (Lubbock, Texas); Patrick J. O'Mahony (Rathfarnam, Ireland); Jeffrey P. Velten (Lubbock, Texas); Melvin J. Oliver (Lubbock, Texas) |
ABSTRACT | Transgenic cells may be selected using temperature sensitive marker proteins. In this method, a population of host cells are transformed with a foreign DNA construct which includes at least one first nucleic acid coding sequence and a second nucleic acid sequence encoding a temperature sensitive marker protein, wherein each of the first and second nucleic acid coding sequences are operatively linked to gene expression control sequences. Suitable temperature sensitive marker proteins which may be used herein include heat shock proteins, heat shock transcription factors, cold regulated proteins (COR), or cold regulated protein transcription factors. Following transformation, the population of cells are cultured under temperature conditions wherein growth of non-transformed cells is suppressed or prevented while growth of cells transformed with the DNA construct is supported or promoted. Thus, survival and/or significant growth of a cell is an indication that the cell has been successfully transformed with the DNA construct. Those cells are considered presumptively positive transformants, and may be recovered. |
FILED | Monday, December 30, 2002 |
APPL NO | 10/331861 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 06, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050906.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page