FedInvent™ Patents
Patent Details for Tuesday, September 13, 2005
This page was updated on Sunday, March 26, 2023 at 07:48 PM GMT
Department of Defense (DOD)
| US 06941633 | Brooks et al. |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Robert T. Brooks (Killingworth, Connecticut); Matthew R. Rader (Middletown, Connecticut) |
| ABSTRACT | An apparatus for separating two flanges, comprising a first prying grip having at least one flange contact member, a second prying grip having at least one flange contact member; and means for separating the flange contact members. |
| FILED | Thursday, August 28, 2003 |
| APPL NO | 10/652644 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/426.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942072 | Klode et al. |
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| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | Harald Klode (Centerville, Ohio); John B. Hageman (Vandalia, Ohio); Paul Rymoff (Bellbrook, Ohio) |
| ABSTRACT | A motor assembly, such as an electro-mechanical-brake (EMB) motor assembly includes an electric motor, a latch gear, a solenoid, and a spring. The latch gear is non-rotatably attached to the drive shaft of the motor. The spring is operatively connected to the solenoid and has a spring projection which is longitudinally-deflectable by energizing the solenoid. The gear tooth is shaped to longitudinally retain the spring projection when the latch gear rotates the gear tooth into engagement with the longitudinally-deflected spring projection. In one example, the latch gear is a parking-brake latch gear and the motor assembly provides a parking brake function for an EMB electric motor which also is used for applying and releasing a vehicle's driving brakes. |
| FILED | Monday, January 13, 2003 |
| APPL NO | 10/341171 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Brakes 188/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942186 | Levin et al. |
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| ASSIGNEE(S) | Star Technology and Research, Inc. (Mount Pleasant, South Carolina) |
| INVENTOR(S) | Eugene M. Levin (Minnetonka, Minnesota); Joseph A. Carroll (Chula Vista, California) |
| ABSTRACT | The present invention improves the orbital maneuvering and power generation capabilities of a system of a satellite(s) connected with a conducting tether(s) by spinning the system about its mass center at an angular rate which is relatively high compared to the average orbital rate. An improvement in tether performance is achieved because at many times during rotation the tether is positioned at much better angles with the magnetic field and significantly higher currents are driven through the tether without destabilizing the system. The current can flow either in the direction of the EMF induced in the tether, or in the reverse direction, depending on the tether orientation with respect to the magnetic field and the mission goals. The reverse current is driven by the onboard power sources. Spinning electrodynamic tether systems can also be lighter and simpler in design and more flexible in operation. |
| FILED | Tuesday, March 05, 2002 |
| APPL NO | 10/092214 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/158.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942202 | Kienholz |
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| ASSIGNEE(S) | CSA Engineering, Inc. (Mountain View, California) |
| INVENTOR(S) | David A. Kienholz (San Jose, California) |
| ABSTRACT | The invention disclosed is a compact and lightweight hybrid pneumatic-magnetic isolator-actuator capable of large force, substantial stroke and bandwidth actuation with near frictionless operation and vibration isolation with very low break frequency. Pneumatic and magnetic forces are applied to a single carriage comprised primarily of a coaxially arranged air piston and coil. The carriage is driven relative to a frame or housing including an internally mounted cylindrical piston sleeve and magnetic actuator body. A combination of air bearings and air bearing piston construction provide for frictionless motion of the carriage relative to the frame. The pneumatic piston provides the actuation force for both static loads and low frequency dynamic loads. An integrally mounted sensor and control unit determine the pressure error resulting at the pneumatic piston. The control unit utilizes the pressure error to drive a high bandwidth magnetic actuation capability in parallel with the pneumatic actuation capability. An air tank of prescribed volume may be connected to the pneumatic piston for effecting a desired air-spring stiffness upon the isolator-actuator. |
| FILED | Friday, November 21, 2003 |
| APPL NO | 10/718353 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Spring devices 267/140.140 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942394 | Alexander et al. |
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| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | John Vernon Alexander (Mesa, Arizona); Daniel Alan Nyhus (Payson, Arizona); Richard Soloski (Mesa, Arizona) |
| ABSTRACT | A race for a bearing, which is mountable to a mount, has an annular bearing surface with a center axis defining an axis of rotation for the bearing and mutually perpendicular radial and transverse directions relative thereto. The race also has a radial wall that is adapted for mounting the race to the mount in a manner such that a bearing transfer load is transferred between the mount and the race in the transverse direction and the race bearing surface maintains its substantially annular shape independently of a load applied to the mount causing distortion of the mount when the race is mounted to the mount and the mount is loaded. |
| FILED | Friday, December 20, 2002 |
| APPL NO | 10/326340 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Bearings 384/585 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942449 | Boyer |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Jason W. Boyer (Middletown, Connecticut) |
| ABSTRACT | An airfoil has first and second ends, leading and trailing edges, and an internal cooling passageway network. A plurality of trailing edge holes extend from the trailing edge to a trailing edge cavity of the network. The trailing edge holes are arrayed at a spacing which progressively changes from the first end toward the second end. |
| FILED | Monday, January 13, 2003 |
| APPL NO | 10/340971 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942730 | Han |
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| ASSIGNEE(S) | H. C. Materials Corporation (Urbana, Illinois) |
| INVENTOR(S) | Pengdi Han (Renton, Washington) |
| ABSTRACT | This invention provides a hybrid Stockbarger zone-leveling melting method for seeded crystallization and the manufacture of homogenous large-sized crystals of lead magnesium niobate-lead titanate (PMN-PT) based solid solutions and related piezocrystals. The invention provides three temperature zones resulting in increased compositional homogeneity and speed of crystal growth, in a cost effective multi-crucible configuration. |
| FILED | Monday, November 04, 2002 |
| APPL NO | 10/288042 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/81 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942747 | Wapner et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Phillip G. Wapner (Palmdale, California); Wesley P. Hoffman (Palmdale, California) |
| ABSTRACT | In the present invention, a technique is described for manufacturing microtube devices which have peripheral geometries that are not uniform along the tube or device axis. These geometries may exist in only one location on the periphery of the microtube device or geometries may be repeated either uniformly or non-uniformly with micron or sub-micron precision along the tube or device axis. The preferred manufacturing process involves forming a complex mandrel, ie., (one, for example, that can not be formed by extrusion or pultrusion under constant processing conditions) and giving it at least one metallic and/or nonmetallic coating by any of a variety of techniques. The complex mandrel can then be removed by appropriate chemical or physical means that do not adversely affect the coating(s) desired for the wall. The result is a microtube structure having an axial profile duplicating that on the mandrel from which it was formed. |
| FILED | Wednesday, December 19, 2001 |
| APPL NO | 10/024836 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/168 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942750 | Chou et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Tsung-Kuan A. Chou (Ann Arbor, Michigan); Khalil Najafi (Ann Arbor, Michigan); Luis P. Bernal (Ann Arbor, Michigan); Peter D. Washabaugh (Ann Arbor, Michigan) |
| ABSTRACT | A method of low-temperature (150-300° C.) patterned wafer bonding of complex 3D MEMS comprising providing a first pre-processed wafer having a first surface and a second pre-processed wafer having a second surface. Photosensitive benzocyclobutene (BCB) polymer is then applied to the first surface of the first wafer in a predetermined pattern to define a bonding layer. The second wafer is then bonded to the first wafer only along the bonding layer. |
| FILED | Wednesday, June 05, 2002 |
| APPL NO | 10/163082 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/272.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942861 | McKee et al. |
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| ASSIGNEE(S) | Henry M. Jackson Foundation for the Advancement of Military Medicine (Rockville, Maryland) |
| INVENTOR(S) | Marian L. McKee (Great Falls, Virginia); Alison D. O'Brien (Bethesda, Maryland); Marian R. Wachtel (Gaithersburg, Maryland) |
| ABSTRACT | The present invention describes the isolation and purification of histidine-tagged functional portions of intimin (his-tagged intimin or his-intimin), a protein associated with the ability of certain strains of pathogenic bacteria to adhere to epithelial cells. The invention further describes the use of intimin as an antigen to promote a protective immune response. In addition, the invention describes the combination of intimin with one or more other antigens and administration of the combination to promote a protective immune response against intimin and the one or more antigens. One aspect of the invention is the administration of intimin to target specific epithelial cells to promote a protective immune response to intimin proteins. Additional aspects of the invention include the use of intimin or intimin combined with one or more antigens and administration of the combination to target gastrointestinal mucosa and stimulate an immune response. Additionally, the invention describes administration of the combination of intimin combined with drugs, to provide a means for targeted delivery of drugs to specific epithelial cells. Other aspects of the invention include the production of antibodies directed against his-intimin and methods of using such antibodies to provide passive immune protection, and in an assay system. |
| FILED | Friday, April 18, 1997 |
| APPL NO | 08/837459 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/169.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943054 | Bocian et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David F. Bocian (Riverside, California); Jonathan S. Lindsey (Raleigh, North Carolina); Zhiming Liu (Riverside, California); Amir A. Yasseri (Riverside, California); Robert S. Loewe (Morrisville, North Carolina) |
| ABSTRACT | This invention provides a new procedure for attaching molecules to semiconductor surfaces, in particular silicon. The molecules, which include, but are not limited to porphyrins and ferrocenes, have been previously shown to be attractive candidates for molecular-based information storage. The new attachment procedure is simple, can be completed in short times, requires minimal amounts of material, is compatible with diverse molecular functional groups, and in some instances affords unprecedented attachment motifs. These features greatly enhance the integration of the molecular materials into the processing steps that are needed to create hybrid molecular/semiconductor information storage devices. |
| FILED | Monday, July 28, 2003 |
| APPL NO | 10/628868 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943190 | Fink et al. |
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| ASSIGNEE(S) | University of Pittsburgh-of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); North Shore-Long Island Jewish Research Institute (Great Neck, New York) |
| INVENTOR(S) | Mitchell P. Fink (Pittsburgh, Pennsylvania); Luis Ulloa (Jackson Heights, New York); Kevin J. Tracey (Old Greenwich, Connecticut); Russell L. Delude (Pittsburgh, Pennsylvania) |
| ABSTRACT | This invention is directed to a method of using a therapeutic composition comprising a compound of an alpha-ketoalkanoic acid (pyruvate) and/or its derivatives for the treatment of cytokine-mediated inflammatory conditions. The compound is an alpha-ketoalkanoic acid, a physiologically acceptable salt of an alpha-ketoalkanoic acid, an ester of an alpha-ketoalkanoic acid, or an amide of an alpha-ketoalkanoic acid. A component for inducing and stabilizing the enol resonance form of the ester at physiological pH values is also disclosed. The cytokine-mediated inflammatory conditions are mediated by, for example, an “early” (Tumor Necrosis Factor (TNF), interleukin-1β (IL-1β)) or “late” (high mobility group B-1 (HMGB-1)) mediator of inflammation. Exemplary cytokine-mediated inflammatory conditions include, but are not limited to, local and systemic inflammation, inflammatory bowel disease (Crohn's disease and ulcerative colitis), rheumatoid arthritis, asthma (including status asthmaticus), sepsis or septic shock, also including inflammatory skin conditions, for example, psoriasis and eczema. |
| FILED | Monday, September 15, 2003 |
| APPL NO | 10/662975 |
| ART UNIT | 1614 — Semiconductors/Memory |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943358 | Andrews et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John M. Andrews (San Diego, California); Stephen H. Lieberman (La Mesa, California); Li-Ming He (San Diego, California) |
| ABSTRACT | A method for developing an algorithm for quantifying the hydrocarbon content of aqueous media includes: a) irradiating aqueous test samples containing hydrocarbons and particulates with light so that fluorescent emissions and scattered light signals are emitted from the test samples; b) detecting fluorescent emissions and the scattered light signals emitted from the test samples; c) generating first data signals representing the intensities of the fluorescent emissions, and second data signals representing the intensities and scatter angles of the second data signals; d) storing representations of the first and second data signals to create a data set; e) dividing the data set into training, test, and validation data sets; f) selecting input parameters from the data set; g) defining and training a neural network having hidden node using the training and the test data sets; and h) validating the neural network using the validation data set. |
| FILED | Thursday, December 05, 2002 |
| APPL NO | 10/318669 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/459.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943660 | Bower et al. |
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| ASSIGNEE(S) | QorTek, Inc. (Williamsport, Pennsylvania) |
| INVENTOR(S) | Bruce Bower (Williamsport, Pennsylvania); Gareth Knowles (Williamsport, Pennsylvania) |
| ABSTRACT | A current control device is described wherein a pressure conduction composite is compressed and decompressed to alter its conductivity and thereby current conduction through the device. The pressure conduction composite is composed of a nonconductive matrix, a conductive filler, and an additive. The invention consists of electrodes and pressure plates contacting the composite. Electrically activated actuators apply a force onto pressures plates. Actuators are composed of a piezoelectric, piezoceramic, electrostrictive, magnetostrictive, and shape memory alloy materials, capable of extending and/or contracting thereby altering pressure and consequently resistivity within the composite. Two or more current control devices are electrically coupled parallel to increase power handling. |
| FILED | Friday, March 26, 2004 |
| APPL NO | 10/810521 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Electrical resistors 338/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943737 | Ryken et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marvin L. Ryken (Oxnard, California); Albert F. Davis (Ventura, California) |
| ABSTRACT | A GPS microstrip antenna designed to receive satellite provided GPS position for use by a nine inch diameter projectile. The GPS microstrip antenna is configured to wrap around the projectile's body without interfering with the aerodynamic design of the projectile. The GPS microstrip antenna operates at 1.575 GHz with a bandwidth of ±10 MHz. Eight microstrip antenna elements equally spaced around the projectile provide for circular polarization and a quasi-omni directional radiation pattern. |
| FILED | Wednesday, March 31, 2004 |
| APPL NO | 10/817409 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943932 | Fujita et al. |
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| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Junichiro Fujita (Wilmington, Massachusetts); Miguel Levy (Chasell, Michigan); Richard M Osgood (Chappaqua, New York) |
| ABSTRACT | A device and method for optical isolation for use in optical systems is disclosed. The device provides for a waveguide optical isolator fabricated using two arms, made of optical waveguides comprising magneto-optical material, in a Mach-Zehnder interferometer configuration. The device of the present invention operates using the TM mode of a light wave and, thus, does not require phase-matching of TM and TE modes. Further, the present invention does not use polarizers to extinguish the optical feed-back. |
| FILED | Friday, April 20, 2001 |
| APPL NO | 10/240521 |
| ART UNIT | 2873 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical: Systems and elements 359/283 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944041 | Li et al. |
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| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration, Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Bin Li (Chantilly, Virginia); Kenneth R. Knowles (Manassas, Virginia); David C. Lawson (Haymarket, Virginia) |
| ABSTRACT | A circuit for accessing a chalcogenide memory array is disclosed. The chalcogenide memory array includes multiple subarrays with rows and columns formed by chalcogenide storage elements. The chalcogenide memory array is accessed by discrete read and write circuits. Associated with a respective one of the subarrays, each of the write circuits includes an independent write 0 circuit and an independent write 1 circuit. Also associated with a respective one of the subarrays, each of the read circuits includes a sense amplifier circuit. In addition, a voltage level control module is coupled to the read and write circuits to ensure that voltages across the chalcogenide storage elements within the chalcogenide memory array do not exceed a predetermined value during read and write operations. |
| FILED | Friday, March 26, 2004 |
| APPL NO | 10/811454 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/113 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944047 | Rotenberg et al. |
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| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Eric Rotenberg (Apex, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | A molecular memory cell includes first and second electrodes. First and second charge storage molecules have respective first and second oxidation potentials and are disposed between the first and second electrodes. A molecular linkage couples the first and second charge storage molecules to the first electrode and provides respective first and second electron transfer rates for the first and second charge storage molecules. The first and second different oxidation potentials are different and/or the first and second electron transfer rates are different. In particular, the second oxidation potential may be greater than the first oxidation potential and the first electron transfer rate may be greater than the second electron transfer rate, such that the first charge storage molecule may be used as fast, volatile primary memory and the second charge storage molecule can be used as slower, less volatile secondary memory. In various embodiments, memory cells can be constructed from an admixture of charge storage molecules or by using a bipartite charge storage molecule. Memory cells can include a molecular transistor incorporating such molecular structures. |
| FILED | Thursday, December 19, 2002 |
| APPL NO | 10/324868 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944131 | Beshai et al. |
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| ASSIGNEE(S) | Nortel Networks Limited (St. Laurent, Canada) |
| INVENTOR(S) | Maged E. Beshai (Stittsville, Canada); Richard Vickers (Kanata, Canada) |
| ABSTRACT | In a communication network comprising nodes and links between the nodes, a controller node disseminates link state information. A nodal routing table exists at each node comprising routes between pairs of nodes. The nodal routing table is either populated by the given node based on network information received from the controlling node or populated at the controlling node and received by the given node. Each node receives heartbeat signals from its neighbouring nodes. An unexpected delay between heartbeat signals may be perceived as a failure of a link. The perceived failure of that link is reported by the perceiving node to the controlling node. Upon receiving link failure information from a node, the controlling node may determine a subset of nodes in the network influenced by the link failure and indicate the link failure to the determined subset of influenced nodes. |
| FILED | Tuesday, December 30, 2003 |
| APPL NO | 10/747077 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/238.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944360 | Li et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Xiaochun Li (Stanford, California); Friedrich Prinz (Woodside, California); Anastasios Golnas (San Francisco, California) |
| ABSTRACT | A sensor embedded in a high temperature metal is incorporated into a sensing system for measuring temperature, strain, or other properties of a metal structure. An optical system transmits light to and receives output signals from the sensor for analysis. With rotating structures, an optical fiber lead transmits light between the sensor and external surface of the structure along its rotational axis, allowing the lead to remain fixed with respect to the optical system as the structure rotates at high speeds. |
| FILED | Thursday, January 29, 2004 |
| APPL NO | 10/768270 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944551 | Chen et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhongping Chen (Irvine, California); Hongwu Ren (Pasadena, California); J. Stuart Nelson (Laguna Niguel, California) |
| ABSTRACT | The Doppler bandwidth extracted from the standard deviation of the frequency shift in phase-resolved optical Doppler tomography (ODT) is used to image the velocity component transverse to the probing beam. The effective numerical aperture (NA) of the optical objective determines the slope of the dependence of the standard deviation on velocity. In the case where the angle between the probing beam and flow direction is within ±15 degrees to the perpendicular, the Doppler frequency shift is very sensitive to angle position while the Doppler bandwidth is insensitive to flow direction. Linear dependence of the flow velocity on the Doppler bandwidth allows accurate measurement of flow velocity without precise determination of flow direction. In addition, it also extends the dynamic range of the average frequency shift mapping method used in the phase-resolved ODT. |
| FILED | Wednesday, March 12, 2003 |
| APPL NO | 10/387668 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944673 | Malan et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Gerald R. Malan (Ann Arbor, Michigan); Farnam Jahanian (Ann Arbor, Michigan) |
| ABSTRACT | A method and system for profiling network flows at a measurement point within a computer network is provided. The method includes measuring network flows having invariant features at a measurement point located within routing infrastructure of the computer network to obtain flow statistics. The method also includes aggregating the flow statistics to obtain a traffic profile of the network flows at the measurement point. The method and system utilize the natural hierarchy in the Internet addressing scheme to provide a means for making tractable measurements of network traffic in high-speed networks. Moreover, the method and system adapt dynamically to the changing underlying traffic characteristics to maintain a maximum memory footprint for the profiles. The method and system adapt by adjusting the level of aggregation of the traffic endpoints along a scale from Interface to fully specified network address. |
| FILED | Tuesday, May 15, 2001 |
| APPL NO | 09/855809 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/237 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944816 | Updegrove |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Darryl Updegrove (Panama City, Florida) |
| ABSTRACT | An automated system for performing a Kepner Tregoe analysis provides a graphical user interface having dedicated data entry screens that include i) a first screen for entering criteria to be used in the Kepner Tregoe analysis, ii) a second screen for entering a relative importance value between each of the criteria and all others of the criteria, iii) a third screen for entering candidates to be used in the Kepner Tregoe analysis, and iv) a fourth screen for entering a raw score associated with each of the criteria for each of the candidates. A separate and dedicated score processor calculates the various parameters associated with the Kepner Tregoe analysis. A text file generator arranges the data for use by a spread sheet processor that will then function solely as part of an output device. |
| FILED | Wednesday, September 05, 2001 |
| APPL NO | 09/947093 |
| ART UNIT | 2179 — Graphical User Interface and Document Processing |
| CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/503 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944843 | Bansal |
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| FUNDED BY |
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| ASSIGNEE(S) | BAE Systems, Information and Electronic Systems Integration, Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Jai P. Bansal (Manassas, Virginia) |
| ABSTRACT | A method for designing a cell-based ASIC device with multiple power supply voltages is disclosed. An ASIC chip image is made without applying power or ground buses to metal layer M1. All fast or high-power circuits are grouped together into high-power logic blocks and synthesized with high-power circuit macro libraries. All slow or low-power circuits are grouped together into low-power logic blocks and synthesized with low power circuit macro libraries. The associate power and ground buses are applied to metal layer M1 in each of the logic blocks. The logic blocks are placed on the ASIC so that different voltage groups are separated by at least one cell. The ASIC is then routed and tested before the mask is released. |
| FILED | Tuesday, August 05, 2003 |
| APPL NO | 10/634229 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 06942865 | Estes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Mary K. Estes (Houston, Texas); Xi Jiang (Virginia Beach, Virginia); David Y. Graham (Houston, Texas) |
| ABSTRACT | Double-stranded cDNA was synthesized from nucleic acid extracted from Norwalk virus purified from stool specimens of volunteers. One clone was isolated from a cDNA library constructed in a pUC-13 vector after amplification of the cDNA. The specificity of this cDNA (pUCNV-953) was shown by hybridization assays. The cDNA reacted with post (but not pre-) infection stool samples from Norwalk volunteers and with highly purified Norwalk virus, but not with other common enteric viruses such as hepatitis A virus and rotavirus. Finally, the probe detected virus in the same fractions of CsCl gradients in which viral antigen was detected using a specific Norwalk virus radioimmunoassay, and particles were detected by immune electron microscopy. Single-stranded RNA probes derived from the DNA clone after subcloning into an in vitro transcription vector were also used to show that the Norwalk virus contains a ssRNA genome of about 8 kb in size. The original clone was also used to detect additional cDNAs which represent at least 7 kb of nucleic acid of the Norwalk genome. The availability of a Norwalk-specific cDNA and the first partial genome sequence information allow rapid cloning of the entire genome and of establishment of sensitive diagnostic assays. Such assays can be based on detection of Norwalk virus nucleic acid or Norwalk viral antigen using polyclonal or monoclonal antibodies to proteins expressed from the cDNA or to synthetic peptides made based on the knowledge of the genome sequence. Assays using proteins deduced from the Norwlk virus genome and produced in expression systmes can measure antibody responses. Vaccines made by recombinant DNA technology are now feasible. |
| FILED | Monday, December 09, 2002 |
| APPL NO | 10/314739 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/204.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942879 | Humes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | H. David Humes (Ann Arbor, Michigan) |
| ABSTRACT | A novel cell seeded hollow fiber bioreactor is described as a potential bioartificial kidney. Endothelial cells along with pericyte, vascular smooth muscle, and/or mesangial cells or any mesenchymally derived support cells are seeded along a hollow fiber in a perfused bioreactor to reproduce the ultrafiltration function and transport function of the kidney. Maintenance of tissue specific function and ultrastructure suggest that this bioreactor provides an economical device for treating renal failure. |
| FILED | Wednesday, December 11, 2002 |
| APPL NO | 10/316000 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/529 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943000 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Roger J. Davis (Princeton, Massachusetts); Richard A. Flavell (Guilford, Connecticut); Pasko Rakic (New Haven, Connecticut); Alan J. Whitmarsh (Shrewsbury, Massachusetts); Chia-Yi Kuan (Wallingford, Connecticut); Derek Di Yang (Carmel, Indiana) |
| ABSTRACT | The c-Jun NH2-terminal kinase (JNK) group of MAP kinases are activated by exposure of cells to environmental stress. The role of JNK in the brain was examined by targeted disruption of the gene that encodes the neuronal isoform JNK3. It was found that JNK3 is required for the normal response to seizure activity. Methods of screening for molecules and compounds that decrease JNK3 expression or activity are described. Such molecules or compounds are useful for treating disorders involving excitotoxicity such as seizure disorders, Alzheimer's disease, Huntington disease, Parkinson's disease, and ischaemia. |
| FILED | Friday, October 02, 1998 |
| APPL NO | 09/165522 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943012 | Ehrhardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junor University (Palo Alto, California) |
| INVENTOR(S) | Anja Ehrhardt (Menlo Park, California); Mark A. Kay (Los Altos, California) |
| ABSTRACT | A helper dependent adenoviral vector system is provided. The subject helper dependent adenoviral vector system is made up of: (1) a “gutless” adenoviral vector that include cis-acting human stuffer DNA that provides for in vivo long term, high level expression of a coding sequence present on the vector; (2) an adenoviral helper vector that is characterized by having an adenoviral genome region flanked by recombinase recognition sites, where the helper vectors further include a non-mammalian endonuclease recognition site positioned outside of the adenoviral genome region; and (3) a mammalian cell that expresses the corresponding recombinase and endonuclease, as well as the adenoviral preterminal and polymerase proteins. Also provided are methods of using the subject systems to produce virions having the subject helper dependent adenoviral vectors encapsulated in an adenoviral capsid. In addition, kits for use in practicing the subject methods are provided. |
| FILED | Monday, March 25, 2002 |
| APPL NO | 10/106831 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943014 | Eastman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Alan Richard Eastman (Hanover, New Hampshire); Ronald J. Krieser (Lebanon, New Hampshire) |
| ABSTRACT | The present invention provides cDNAs encoding deoxyribonuclease IIβ and isolated, purified deoxyribonuclease IIβ proteins. Antibodies against this protein and antisense agents targeted to a cDNA or corresponding mRNA encoding deoxyribonuclease IIβ are provided. In addition, methods of identifying and using modulators of deoxyribonuclease IIβ activity are described. |
| FILED | Monday, April 02, 2001 |
| APPL NO | 10/240709 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943017 | Hutchinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Charles R. Hutchinson (Oakland, California); Jonathan Kennedy (Hayward, California); Cheonseok Park (Seoul, South Korea) |
| ABSTRACT | A method of increasing the production of lovastatin or monacolin J in a lovastatin-producing or non-lovastatin-producing organism is disclosed. In one embodiment, the method comprises the steps of transforming an organism with the A. terreus D4B segment, wherein the segment is translated and where an increase in lovastatin production occurs. |
| FILED | Thursday, March 28, 2002 |
| APPL NO | 10/109310 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943018 | Auernhammer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Christoph J. Auernhammer (München-Pasing, Germany); Shlomo Melmed (Los Angeles, California) |
| ABSTRACT | Disclosed is a transgenic vertebrate cell containing a nucleic acid construct comprising a murine SOCS-3 promoter, or an operative fragment thereof, or an operative derivative of either of these. |
| FILED | Monday, April 29, 2002 |
| APPL NO | 10/136224 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943019 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James M. Wilson (Gladwyne, Pennsylvania); Weidong Xiao (Fort Washington, Pennsylvania) |
| ABSTRACT | Methods for efficient production of recombinant AAV employ a host cell containing a first nucleic acid molecule comprising from 5′ to 3′, a parvovirus P5 promoter, a spacer, an AAV rep sequence and an AAV cap gene sequence, wherein said spacer is of sufficient size to reduce expression of the rep78 and rep68 gene products; a second nucleic acid molecule comprising a minigene comprising a transgene flanked by AAV inverse terminal repeats (ITRs) and under the control of regulatory sequences directing expression thereof in a host cell; and helper functions essential to the replication and packaging of rAAV, which functions are not provided by the first or second nucleic acid molecules. Host cells and molecule constructs are also described. |
| FILED | Thursday, September 26, 2002 |
| APPL NO | 10/255527 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943021 | Klausner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | MatTek Corporation (Ashland, Massachusetts) |
| INVENTOR(S) | Mitchell Klausner (Sharon, Massachusetts); Seyoum Ayehunie (Natick, Massachusetts); Joseph Kubilus (Dracut, Massachusetts) |
| ABSTRACT | Disclosed is a cervico-vaginal tissue equivalent comprised of vaginal epithelial cells and immune cells, cultured at the air-liquid interface. The tissue equivalent is capable of being infected with a sexually transmitted pathogen such as a virus (e.g., HIV), a bacteria, a helminthic parasite, or a fungus. The tissue equivalent is also capable of undergoing an allergic-type reaction or an irritant-type reaction. The tissue equivalent is characterized as having nucleated basal layer cells and nucleated suprabasal layer cells, and further as having cell layers external to the suprabasal layer progressively increasing in glycogen content and progressively decreasing in nuclei content. Immune cells of the tissue equivalent are primarily located in the basal and suprabasal layers. Also disclosed are methods for producing the tissue equivalent. The methods involve providing vaginal epithelial cells and immune cells, seeding the cells onto a porous support, and co culturing the seeded cells at the air-liquid interface under conditions appropriate for differentiation. One such method disclosed is for generation of the tissue equivalent in serum free medium. Specific cells from which the tissue equivalent is generated, and also specific preferred components of the medium in which the tissue equivalent is generated are provided. Also disclosed is a cervico-vaginal tissue equivalent produced by the methods disclosed herein. |
| FILED | Friday, June 07, 2002 |
| APPL NO | 10/165267 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943033 | Van Zijl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Peter C. M. Van Zijl (Ellicott City, Maryland); Jinyuan Zhou (Baltimore, Maryland) |
| ABSTRACT | Featured is an MRI/NMR methodology or process to detect amide protons of endogenous mobile proteins and peptides via the water signal. Such methods and processes can be used for the purposes of detection of pH effects and labile amide proton content of mobile proteins/peptides or content changes thereto using MRI Also featured are methods whereby assessment of determined pH effects and amide proton content or content changes and related mobile protein and/or peptide content or content changes can be used in connection with diagnosis, program and treatment of brain related disorders and diseases, cardiac disorders and diseases, and cancer and to use such methods for monitoring, detecting and assessing protein and peptide content in vivo and pathologically for any of a number of diseases or disorders of a human body, including but not limited to cancers, ischemia, Alzheimers and Parkinsons. |
| FILED | Friday, December 13, 2002 |
| APPL NO | 10/319864 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943190 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh-of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); North Shore-Long Island Jewish Research Institute (Great Neck, New York) |
| INVENTOR(S) | Mitchell P. Fink (Pittsburgh, Pennsylvania); Luis Ulloa (Jackson Heights, New York); Kevin J. Tracey (Old Greenwich, Connecticut); Russell L. Delude (Pittsburgh, Pennsylvania) |
| ABSTRACT | This invention is directed to a method of using a therapeutic composition comprising a compound of an alpha-ketoalkanoic acid (pyruvate) and/or its derivatives for the treatment of cytokine-mediated inflammatory conditions. The compound is an alpha-ketoalkanoic acid, a physiologically acceptable salt of an alpha-ketoalkanoic acid, an ester of an alpha-ketoalkanoic acid, or an amide of an alpha-ketoalkanoic acid. A component for inducing and stabilizing the enol resonance form of the ester at physiological pH values is also disclosed. The cytokine-mediated inflammatory conditions are mediated by, for example, an “early” (Tumor Necrosis Factor (TNF), interleukin-1β (IL-1β)) or “late” (high mobility group B-1 (HMGB-1)) mediator of inflammation. Exemplary cytokine-mediated inflammatory conditions include, but are not limited to, local and systemic inflammation, inflammatory bowel disease (Crohn's disease and ulcerative colitis), rheumatoid arthritis, asthma (including status asthmaticus), sepsis or septic shock, also including inflammatory skin conditions, for example, psoriasis and eczema. |
| FILED | Monday, September 15, 2003 |
| APPL NO | 10/662975 |
| ART UNIT | 1614 — Semiconductors/Memory |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
06943191 — Disubstituted lavendustin A analogs and pharmaceutical composition comprising the analogs
| US 06943191 | Narayanan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Venkatachala L. Narayanan (Gaithersburg, Maryland); Edward A. Sausville (Silver Spring, Maryland); Gurmeet Kaur (Germantown, Maryland); Ravi K. Varma (Rockville, Maryland) |
| ABSTRACT | Disubstituted lavendustin A analogs that are PTK inhibitors having antiproliferative activity are described. Preferred compounds of the disclosure, without limitation, satisfy either Formula 1 or Formula 2. The present disclosure also provides pharmaceutical compositions comprising effective amounts of disubstituted lavendustin A analogs and potentially comprising other active ingredients, other materials conventionally used in the formulation of pharmaceutical compositions, and mixtures thereof. The compounds and compositions of the disclosure can be used for treating subjects to, for example, inhibit the proliferation of living cells in the treatment of proliferative diseases. |
| FILED | Wednesday, February 24, 1999 |
| APPL NO | 09/623000 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/535 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943194 | Pettit et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents, acting for and on behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | George R. Pettit (Paradise Valley, Arizona); Brian Toki (Linwood, Washington) |
| ABSTRACT | A newly discovered antineoplastic compound denominated “phenstatin” is herein described as are synthetic methods for producing phenstatin and the active prodrug thereof. Phenstatin was converted to the sodium phosphate prodrug (3d) by a dibenzylphosphite phosphorylation and subsequent hydrogenolysis sequence 3b→3c→3d. Phenstatin (3b) was found to be a potent inhibitor of tubulin polymerization and the binding of colchicine to tubulin comparable to combretastatin A-4 (1b). |
| FILED | Saturday, January 09, 1999 |
| APPL NO | 09/582952 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/576 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943246 | Rice et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Charles M. Rice (University City, Missouri); Alexander A. Kolykhalov (St. Louis, Missouri) |
| ABSTRACT | The invention relates to the discovery of a novel RNA sequence at the 3′ terminal sequence of hepatitis C virus (HCV) genome RNA. Included in the invention are the 3′ sequence, its complement, and their use for nucleic-acid based diagnostics and for developing and evaluating novel anti-HCV therapies. This sequence element, which is conserved among HCV genotypes, is likely to be essential for viral replication, and required for construction of full-length HCV cDNA clones capable of yielding infectious RNA, progeny virus or replication-competent HCV replicons. Such functional clones are useful tools for evaluation of therapeutic approaches and as substrates for developing candidate attenuated or inactivated HCV derivatives for vaccination against HCV. |
| FILED | Thursday, May 30, 2002 |
| APPL NO | 10/158314 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/24.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943347 | Willoughby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ross Clark Willoughby (Pittsbugh, Pennsylvania); Edward William Sheehan (Pittsburgh, Pennsylvania) |
| ABSTRACT | An improved tube for accepting gas-phase ions and particles contained in a gas by allowing substantially all the gas-phase ions and gas from an ion source at or greater than atmospheric pressure to flow into the tube and be transferred to a lower pressure region. Transport and motion of the ions through the tube is determined by a combination of viscous forces exerted on the ions by the flowing gas molecules and electrostatic forces causing the motion of the ions through the tube and away from the walls of the tube. More specifically, the tube is made up of stratified elements, wherein DC potentials are applied to the elements so that the DC voltage on any element determines the electric potential experience by the ions as they pass through the tube. A precise electrical gradient is maintained along the length of the stratified tube to insure the transport of the ions. Embodiments of this invention are methods and devices for improving the sensitivity of mass spectrometry or ion mobility spectrometers when coupled to atmospheric and above atmospheric pressure ionization sources. An alternate embodiment of this invention applies an AC voltage to one or more of the conducting elements in the laminate. |
| FILED | Friday, October 17, 2003 |
| APPL NO | 10/688021 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944551 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhongping Chen (Irvine, California); Hongwu Ren (Pasadena, California); J. Stuart Nelson (Laguna Niguel, California) |
| ABSTRACT | The Doppler bandwidth extracted from the standard deviation of the frequency shift in phase-resolved optical Doppler tomography (ODT) is used to image the velocity component transverse to the probing beam. The effective numerical aperture (NA) of the optical objective determines the slope of the dependence of the standard deviation on velocity. In the case where the angle between the probing beam and flow direction is within ±15 degrees to the perpendicular, the Doppler frequency shift is very sensitive to angle position while the Doppler bandwidth is insensitive to flow direction. Linear dependence of the flow velocity on the Doppler bandwidth allows accurate measurement of flow velocity without precise determination of flow direction. In addition, it also extends the dynamic range of the average frequency shift mapping method used in the phase-resolved ODT. |
| FILED | Wednesday, March 12, 2003 |
| APPL NO | 10/387668 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06941785 | Haynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Howard D. Haynes (Knoxville, Tennessee); Daryl F. Cox (Knoxville, Tennessee); Donald E. Welch (Oak Ridge, Tennessee) |
| ABSTRACT | A pump diagnostic system and method comprising current sensing probes clamped on electrical motor leads of a pump for sensing only current signals on incoming motor power, a signal processor having a means for buffering and anti-aliasing current signals into a pump motor current signal, and a computer having a means for analyzing, displaying, and reporting motor current signatures from the motor current signal to determine pump health using integrated motor and pump diagnostic parameters. |
| FILED | Tuesday, May 13, 2003 |
| APPL NO | 10/437630 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Metal deforming 072/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942219 | Khonsari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Michael M. Khonsari (Baton Rouge, Louisiana); Anoop K. Somanchi (Baton Rouge, Louisiana) |
| ABSTRACT | An apparatus and method to enhance the overall performance of mechanical seals in one of the following ways: by reducing seal face wear, by reducing the contact surface temperature, or by increasing the life span of mechanical seals. The apparatus is a mechanical seal (e.g., single mechanical seals, double mechanical seals, tandem mechanical seals, bellows, pusher mechanical seals, and all types of rotating and reciprocating machines) comprising a rotating ring and a double-tier mating ring. In a preferred embodiment, the double-tier mating ring comprises a first and a second stationary ring that together form an agitation-inducing, guided flow channel to allow for the removal of heat generated at the seal face of the mating ring by channeling a coolant entering the mating ring to a position adjacent to and in close proximity with the interior surface area of the seal face of the mating ring. |
| FILED | Monday, October 20, 2003 |
| APPL NO | 10/689406 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Seal for a joint or juncture 277/360 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942450 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Siemens Westinghouse Power Corporation (Orlando, Florida) |
| INVENTOR(S) | Wen-Ching Yang (Export, Pennsylvania); Maria E. Stampahar (Trafford, Pennsylvania) |
| ABSTRACT | A detection system for identifying airfoils having a cooling systems with orifices that are plugged with contaminants or with showerheads having a portion burned off. The detection system measures pressures at different locations and calculates or measures a differential pressure. The differential pressure may be compared with a known benchmark value to determine whether the differential pressure has changed. Changes in the differential pressure may indicate that one or more of the orifices in a cooling system of an airfoil are plugged or that portions of, or all of, a showerhead has burned off. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646875 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942729 | Voronov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Diamond Materials, INC (Piscataway, New Jersey) |
| INVENTOR(S) | Oleg A. Voronov (East Stroudsburg, Pennsylvania) |
| ABSTRACT | A design for high pressure/high temperature apparatus and reaction cell to achieve ˜30 GPa pressure in ˜1 cm volume and ˜100 GPa pressure in ˜1 mm volumes and 20-5000° C. temperatures in a static regime. The device includes profiled anvils (28) action on a reaction cell (14, 16) containing the material (26) to be processed. The reaction cell includes a heater (18) surrounded by insulating layers and screens. Surrounding the anvils are cylindrical inserts and supporting rings (30-48) whose hardness increases towards the reaction cell. These volumes may be increased considerably if applications require it, making use of presses that have larger loading force capability, larger frames and using larger anvils. |
| FILED | Thursday, August 16, 2001 |
| APPL NO | 10/362320 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/68 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942773 | Olivares et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | José A. Olivares (Los Alamos, New Mexico); Peter C. Stark (Los Alamos, New Mexico) |
| ABSTRACT | An electrophoretic device separates and detects particles such as DNA fragments, proteins, and the like. The device has a capillary which is coated with a coating with a low refractive index such as Teflon® AF. A sample of particles is fluorescently labeled and injected into the capillary. The capillary is filled with an electrolyte buffer solution. An electrical field is applied across the capillary causing the particles to migrate from a first end of the capillary to a second end of the capillary. A detector light beam is then scanned along the length of the capillary to detect the location of the separated particles. The device is amenable to a high throughput system by providing additional capillaries. The device can also be used to determine the actual size of the particles and for DNA sequencing. |
| FILED | Friday, January 26, 2001 |
| APPL NO | 09/771277 |
| ART UNIT | 1753 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/452 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942840 | Broderick |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ADA Technologies, Inc. (Littleton, Colorado) |
| INVENTOR(S) | Thomas E. Broderick (Arvada, Colorado) |
| ABSTRACT | The present invention is directed to a process and apparatus for removing and stabilizing mercury from mercury-containing gas streams. A gas stream containing vapor phase elemental and/or speciated mercury is contacted with reagent, such as an oxygen-containing oxidant, in a liquid environment to form a mercury-containing precipitate. The mercury-containing precipitate is kept or placed in solution and reacts with one or more additional reagents to form a solid, stable mercury-containing compound. |
| FILED | Monday, September 23, 2002 |
| APPL NO | 10/253944 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942994 | Nikolau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Basil J. Nikolau (Ames, Iowa); Eve S. Wurtele (Ames, Iowa); David J. Oliver (Ames, Iowa); Robert Behal (Ames, Iowa); Patrick S. Schnable (Ames, Iowa); Jinshan Ke (Foster City, California); Jerry L. Johnson (St. Paul, Minnesota); Carolyn C. Allred (Ames, Iowa); Beth Fatland (Ames, Iowa); Isabelle Lutziger (Ames, Iowa); Tsui-Jung Wen (Ames, Iowa) |
| ABSTRACT | The present invention provides nucleic acid and amino acid sequences of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL), Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 and ALDH-4. The present invention also provides a recombinant vector comprising a nucleic acid sequence encoding one of the aforementioned enzymes, an antisense sequence thereto or a ribozyme therefor, a cell transformed with such a vector, antibodies to the enzymes, a plant cell, a plant tissue, a plant organ or a plant in which the level of an enzyme has been altered, and a method of producing such a plant cell, plant tissue, plant organ or plant. Desirably, alteration of the level of enzyme results in an alteration of the level of acetyl CoA in the plant cell, plant tissue, plant organ or plant. In addition, the present invention provides a recombinant vector comprising an antisense sequence of a nucleic acid sequence encoding pyruvate decarboxylase (PDC), the E1α subunit of pPDH, the E1β subunit of pPDH, the E2 subunit of pPDH, mitochondrial pyruvate dehydrogenase (mtPDH) or aldehyde dehydrogenase (ALDH) or a ribozyme that can cleave an RNA molecule encoding PDC, E1α pPDH, E1β pPDH, E2 pPDH, mtPDH or ALDH. |
| FILED | Wednesday, November 13, 2002 |
| APPL NO | 10/293865 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942998 | Ooteghem |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Suellen Van Ooteghem (Morgantown, West Virginia) |
| ABSTRACT | A method for producing hydrogen gas is provided comprising selecting a bacteria from the Order Thermotogales, subjecting the bacteria to a feedstock and to a suitable growth environment having an oxygen concentration below the oxygen concentration of water in equilibrium with air; and maintaining the environment at a predetermined pH and at a temperature of at least approximately 45° C. for a time sufficient to allow the bacteria to metabolize the feedstock. |
| FILED | Friday, May 10, 2002 |
| APPL NO | 10/141863 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/168 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943006 | Kayser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Alps Electric Co., Ltd. (Tokyo, Japan) |
| INVENTOR(S) | Kevin J. Kayser (Chesterfield, Michigan); John J. Kilbane, II (Woodstock, Illinois) |
| ABSTRACT | A method for selective cleavage of C—N bonds genes that encode for at least one enzyme suitable for conversion of carbazole to 2-aminobiphenyl-2,3-diol are combined with a gene encoding an amidase suitable for selectively cleaving a C—N bond in 2-aminobiphenyl-2,3-diol, forming an operon that encodes for cleavage of both C—N bonds of said carbazole. The operon is inserted into a host culture which, in turn, is contacted with the carbazole, resulting in selective cleavage of both C—N bonds of the carbazole. Also disclosed is a new microorganism that expresses a carbazole degradation trait constitutively and a method for degrading carbazole employing this microorganism. |
| FILED | Tuesday, September 09, 2003 |
| APPL NO | 10/658691 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943353 | Elmore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UD Technology Corporation (Newark, Delaware) |
| INVENTOR(S) | Douglas L. Elmore (Bartlett, Tennessee); John F. Rabolt (Greenville, Delaware); Mei-Wei Tsao (Wilmington, Delaware) |
| ABSTRACT | An apparatus and method capable of providing spatially multiplexed IR spectral information simultaneously in real-time for multiple samples or multiple spatial areas of one sample using IR absorption phenomena requires no moving parts or Fourier Transform during operation, and self-compensates for background spectra and degradation of component performance over time. IR spectral information and chemical analysis of the samples is determined by using one or more IR sources, sampling accessories for positioning the samples, optically dispersive elements, a focal plane array (FPA) arranged to detect the dispersed light beams, and a processor and display to control the FPA, and display an IR spectrograph. Fiber-optic coupling can be used to allow remote sensing. Portability, reliability, and ruggedness is enhanced due to the no-moving part construction. Applications include determining time-resolved orientation and characteristics of materials, including polymer monolayers. Orthogonal polarizers may be used to determine certain material characteristics. |
| FILED | Thursday, April 01, 2004 |
| APPL NO | 10/708927 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/339.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943357 | Srivastava et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Alok Mani Srivastava (Niskayuna, New York); Anant Achyut Setlur (Niskayuna, New York); Holly Ann Comanzo (Niskayuna, New York); John William Devitt (Clifton Park, New York); James Anthony Ruud (Delmar, New York); Luke Nathaniel Brewer (Clifton Park, New York) |
| ABSTRACT | A method for determining past-service conditions and/or remaining useful life of a component of a combustion engine and/or a thermal barrier coating (“TBC”) of the component comprises providing a photoluminescent (“PL”) material in the TBC, directing an exciting radiation at the TBC, measuring the intensity of a characteristic peak in the emission spectrum of the PL material, and correlating the intensity of the characteristic peak or another quantity derived therefrom to an amount of a new phase that has been formed as a result of the exposure of the component to extreme temperatures. An apparatus for carrying out the method comprises a radiation source that provides the exciting radiation to the TBC, a radiation detector for detecting radiation emitted by the PL material, and means for relating a characteristic of the emission spectrum of the PL material to the amount of the new phase in the TBC, thereby inferring the past-service conditions or the remaining useful life of the component. |
| FILED | Tuesday, February 17, 2004 |
| APPL NO | 10/779826 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/458.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943359 | Vardeny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Utah (Salt Lake City, Utah) |
| INVENTOR(S) | Z. Valy Vardeny (Salt Lake City, Utah); Sergey Li (Salt Lake City, Utah); Matthew C. Delong (Salt Lake City, Utah); Xiaomei Jiang (Salt Lake City, Utah) |
| ABSTRACT | Organic materials exposed to an electron beam for patterning a substrate (1) to make an optoelectronic organic device which includes a source, a drain, gate dielectric layer (4), and a substrate for emitting light. |
| FILED | Wednesday, March 13, 2002 |
| APPL NO | 10/471356 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943964 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Southeastern Univ. Research Assn. (Newport News, Virginia) |
| INVENTOR(S) | Shukui Zhang (Yorktown, Virginia); Michelle D. Shinn (Newport News, Virginia) |
| ABSTRACT | A single lens laser beam shaper for converting laser beams from any spatial profile to a flat-top or uniform spatial profile. The laser beam shaper includes a lens having two aspheric surfaces. The beam shaper significantly simplifies the overall structure in comparison with conventional 2-element systems and therefore provides great ease in alignment and reduction of cost. |
| FILED | Tuesday, June 01, 2004 |
| APPL NO | 10/858143 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/708 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06942728 | Caillat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Thierry Caillat (Pasadena, California); Alexander Borshchevsky (Santa Monica, California); Jean-Pierre Fleurial (Duarte, California) |
| ABSTRACT | The present invention is embodied in high performance p-type thermoelectric materials having enhanced thermoelectric properties and the methods of preparing such materials. In one aspect of the invention, p-type semiconductors of formula Zn4−xAxSb3−yBy wherein 0≦x≦4, A is a transition metal, B is a pnicogen, and 0≦y≦3 are formed for use in manufacturing thermoelectric devices with substantially enhanced operating characteristics and improved efficiency. Two methods of preparing p-type Zn4Sb3 and related alloys of the present invention include a crystal growth method and a powder metallurgy method. |
| FILED | Tuesday, October 01, 2002 |
| APPL NO | 10/262807 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943619 | Shuler, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert L. Shuler, Jr. (Friendswood, Texas) |
| ABSTRACT | A method and apparatus is described that filters an electrical signal. The filtering uses a capacitor multiplier circuit where the capacitor multiplier circuit uses at least one amplifier circuit and at least one capacitor. A filtered electrical signal results from a direct connection from an output of the at least one amplifier circuit. |
| FILED | Wednesday, May 21, 2003 |
| APPL NO | 10/443233 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/554 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943621 | Shuler, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert L. Shuler, Jr. (Friendswood, Texas) |
| ABSTRACT | A method and apparatus for an acquisition system includes a plurality of sensor input signal lines. At least one of the plurality of sensor input signal lines operatively connects to at least one of a plurality of amplifier circuits. At least one of the plurality of amplifier circuits operatively connects to at least one of a plurality of filter circuits. |
| FILED | Wednesday, May 21, 2003 |
| APPL NO | 10/443234 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Amplifiers 330/51 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943838 | Fossum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Eric R. Fossum (La Crescenta, California); Junichi Nakamura (Tokyo, Japan); Sabrina E. Kemeny (La Crescenta, California) |
| ABSTRACT | An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node. There is also a readout circuit, part of which can be disposed at the bottom of each column of cells and be common to all the cells in the column. A Simple Floating Gate (SFG) pixel structure could also be employed in the imager to provide a non-destructive readout and smaller pixel sizes. |
| FILED | Tuesday, December 26, 2000 |
| APPL NO | 09/749989 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Television 348/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943934 | Ilchenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Vladimir Ilchenko (La Canada, California); Andrey B. Matsko (Pasadena, California); Anatoliy Savchenkov (La Crescenta, California); Lutfollah Maleki (Pasadena, California) |
| ABSTRACT | Whispering gallery mode (WGM) optical resonators comprising nonlinear optical materials, where the nonlinear optical material of a WGM resonator includes a plurality of sectors within the optical resonator and nonlinear coefficients of two adjacent sectors are oppositely poled. |
| FILED | Wednesday, May 28, 2003 |
| APPL NO | 10/447673 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944352 | Yadid-Pecht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Orly Yadid-Pecht (Haifa, Israel); Barmak Mansoorian (San Diego, California); Bedabrata Pain (Los Angeles, California) |
| ABSTRACT | Hardware circuit for median calculation in an active pixel sensor. |
| FILED | Monday, November 05, 2001 |
| APPL NO | 10/011967 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944504 | Arndt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | G. Dickey Arndt (Friendswood, Texas); Phong H. Ngo (Friendswood, Texas); James R. Carl (Houston, Texas); W. Raffoul George (Houston, Texas) |
| ABSTRACT | Methods, simulations, and apparatus are provided that may be utilized for medical treatments which are especially suitable for treatment of benign prostatic hyperplasia (BPH). In a preferred embodiment, a plurality of separate microwave antennas are utilized to heat prostatic tissue to promote necrosing of the prostatic tissue that relieves the pressure of the prostatic tissue against the urethra as the body reabsorbs the necrosed or dead tissue. By utilizing constructive and destructive interference of the microwave transmission, the energy can be deposited on the tissues to be necrosed while protecting other tissues such as the urethra. Saline injections to alter the conductivity of the tissues may also be used to further focus the energy deposits. A computer simulation is provided that can be used to predict the resulting temperature profile produced in the prostatic tissue. By changing the various control features of one or more catheters and the methods of applying microwave energy, a temperature profile can be predicted and produced that is similar to the temperature profile desired for the particular patient. |
| FILED | Tuesday, November 19, 2002 |
| APPL NO | 10/302323 |
| ART UNIT | 3739 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06942905 | Petschek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Rolfe G. Petschek (Shaker Heights, Ohio); Daniel Harrison (Cleveland Heights, Ohio); Michael Fisch (Lakewood, Ohio) |
| ABSTRACT | The present invention consists of materials and a processing method for coating rigid-rod poly(ionomers) or salts thereof, in a solvent system, directionally on charged surfaces resulting in the formation of liquid crystal display surfaces with planar alignment and pretilt. |
| FILED | Wednesday, January 21, 1998 |
| APPL NO | 09/284828 |
| ART UNIT | 1756 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Stock material or miscellaneous articles 428/1.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942986 | Bassler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Princeton University (Princeton, New Jersey); University Technologies International (Alberta, Canada) |
| INVENTOR(S) | Bonnie L. Bassler (Princeton, New Jersey); Michael G. Surette (Calgary, Canada) |
| ABSTRACT | The production of a purified extracellular bacterial signal called autoinducer-2 is regulated by changes in environmental conditions associated with a shift from a free-living existence to a colonizing or pathogenic existence in a host organism. Autoinducer-2 stimulates LuxQ luminescence genes, and is believed also to stimulate a variety of pathogenesis related genes in the bacterial species that produce it. A new class of bacterial genes is involved in the biosynthesis of autoinducer-2. |
| FILED | Friday, September 21, 2001 |
| APPL NO | 09/961452 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06942994 | Nikolau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Basil J. Nikolau (Ames, Iowa); Eve S. Wurtele (Ames, Iowa); David J. Oliver (Ames, Iowa); Robert Behal (Ames, Iowa); Patrick S. Schnable (Ames, Iowa); Jinshan Ke (Foster City, California); Jerry L. Johnson (St. Paul, Minnesota); Carolyn C. Allred (Ames, Iowa); Beth Fatland (Ames, Iowa); Isabelle Lutziger (Ames, Iowa); Tsui-Jung Wen (Ames, Iowa) |
| ABSTRACT | The present invention provides nucleic acid and amino acid sequences of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL), Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 and ALDH-4. The present invention also provides a recombinant vector comprising a nucleic acid sequence encoding one of the aforementioned enzymes, an antisense sequence thereto or a ribozyme therefor, a cell transformed with such a vector, antibodies to the enzymes, a plant cell, a plant tissue, a plant organ or a plant in which the level of an enzyme has been altered, and a method of producing such a plant cell, plant tissue, plant organ or plant. Desirably, alteration of the level of enzyme results in an alteration of the level of acetyl CoA in the plant cell, plant tissue, plant organ or plant. In addition, the present invention provides a recombinant vector comprising an antisense sequence of a nucleic acid sequence encoding pyruvate decarboxylase (PDC), the E1α subunit of pPDH, the E1β subunit of pPDH, the E2 subunit of pPDH, mitochondrial pyruvate dehydrogenase (mtPDH) or aldehyde dehydrogenase (ALDH) or a ribozyme that can cleave an RNA molecule encoding PDC, E1α pPDH, E1β pPDH, E2 pPDH, mtPDH or ALDH. |
| FILED | Wednesday, November 13, 2002 |
| APPL NO | 10/293865 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943031 | Farquharson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Real-Time Analyzers, Inc. (Middletown, Connecticut) |
| INVENTOR(S) | Stuart Farquharson (Meriden, Connecticut); Paul Maksymiuk (South Windsor, Connecticut) |
| ABSTRACT | Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. The use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such apparatus and enhances the efficiency of the method. |
| FILED | Friday, February 21, 2003 |
| APPL NO | 10/372621 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943032 | Farquharson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Real-Time Analyzers, Inc. (Middletown, Connecticut) |
| INVENTOR(S) | Stuart Farquharson (Meriden, Connecticut); Paul Maksymiuk (South Windsor, Connecticut) |
| ABSTRACT | Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. Measurements are made at multiple points along the length of a column or channel to increase, very significantly, the speed of analysis, and use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such apparatus and enhances the efficiency of the method. |
| FILED | Friday, February 21, 2003 |
| APPL NO | 10/372622 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06943353 | Elmore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UD Technology Corporation (Newark, Delaware) |
| INVENTOR(S) | Douglas L. Elmore (Bartlett, Tennessee); John F. Rabolt (Greenville, Delaware); Mei-Wei Tsao (Wilmington, Delaware) |
| ABSTRACT | An apparatus and method capable of providing spatially multiplexed IR spectral information simultaneously in real-time for multiple samples or multiple spatial areas of one sample using IR absorption phenomena requires no moving parts or Fourier Transform during operation, and self-compensates for background spectra and degradation of component performance over time. IR spectral information and chemical analysis of the samples is determined by using one or more IR sources, sampling accessories for positioning the samples, optically dispersive elements, a focal plane array (FPA) arranged to detect the dispersed light beams, and a processor and display to control the FPA, and display an IR spectrograph. Fiber-optic coupling can be used to allow remote sensing. Portability, reliability, and ruggedness is enhanced due to the no-moving part construction. Applications include determining time-resolved orientation and characteristics of materials, including polymer monolayers. Orthogonal polarizers may be used to determine certain material characteristics. |
| FILED | Thursday, April 01, 2004 |
| APPL NO | 10/708927 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/339.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944126 | Varma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anujan Varma (Santa Cruz, California); Christos Tryfonas (Foster City, California) |
| ABSTRACT | A method is disclosed for efficiently determining exact loss rate, or a loss curve, for a traffic source transmitted at a specified rate. The loss curve of a traffic source characterizes the loss rate of the traffic stream as a function of the allocated buffer size for a given transmission rate. Utilization of loss curve characterization allows for optimal resource allocation for a given source within a packet network. The present invention provides a deterministic method for computing the loss curve of a traffic source, examples of which include multimedia streams, elementary video streams, and MPEG-2 transport streams. The present method exploits the piecewise linearity of the loss curve and computes only the points at which the slope of the loss curve changes. The method is memory efficient and executes rapidly, for instance, a loss curve for a two-hour elementary video stream was determined within eleven seconds on a conventional Sun Ultra-2™ workstation. |
| FILED | Tuesday, December 19, 2000 |
| APPL NO | 09/741747 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/233 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 06944101 | Johns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
| INVENTOR(S) | Earl C. Johns (Sewickley, Pennsylvania); William A. Challener (Sewickley, Pennsylvania) |
| ABSTRACT | A magnetic recording device is provided according to the present invention for magnetic recording on a recording medium. The magnetic recording device includes a magnetic pole and a C-aperture structure disposed adjacent the magnetic pole. A focusing element receives light from a light source and focuses the received light onto the C-aperture structure, such that the light incident upon the C-aperture structure and a magnetic flux flowing through the magnetic pole are co-locatable on a recording medium disposed adjacent to the magnetic recording device. The focusing element may include a planar waveguide receiving and focusing the light onto the C-aperture structure. |
| FILED | Monday, June 23, 2003 |
| APPL NO | 10/601409 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Dynamic information storage or retrieval 369/13.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06944112 | Challener |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
| INVENTOR(S) | William A. Challener (Sewickley, Pennsylvania) |
| ABSTRACT | A heat assisted magnetic recording head having a planar waveguide for heating a recording medium proximate to where a write pole of the recording head applies a magnetic write field thereto. The planar waveguide includes at least one edge, which may have a substantially parabolic shape, that is shaped to reflect an electromagnetic wave to a focal point within the planar waveguide. The planar waveguide includes a truncated end adjacent the focal point such that the truncated end intersects the focal point. |
| FILED | Wednesday, March 19, 2003 |
| APPL NO | 10/392015 |
| ART UNIT | 2652 — Videophones and Telephonic Communications |
| CURRENT CPC | Dynamic information storage or retrieval 369/112.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 06943010 | Dodo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hortense W. Dodo (Huntsville, Alabama); Charles J. Arntzen (Ithaca, New York); Olga Martha Viquez (Huntsville, Alabama); Koffi N'da Konan (Huntsville, Alabama) |
| ABSTRACT | An allergen-free transgenic peanut seed is produced by recombinant methods. Peanut plants are transformed with multiple copies of each of the allergen genes, or fragments thereof, to suppress gene expression and allergen protein production. Alternatively, peanut plants are transformed with peanut allergen antisense genes introduced into the peanut genome as antisense fragments, sense fragments, or combinations of both antisense and sense fragments. Peanut transgenes are under the control of the 35S promoter, or the promoter of the Ara h2 gene to produce antisense RNAs, sense RNAs, and double-stranded RNAs for suppressing allergen protein production in peanut plants. A full length genomic clone for allergen Ara h2 is isolated and sequenced. The ORF is 622 nucleotides long. The predicted encoded protein is 207 amino acids long and includes a putative transit peptide of 21 residues. One polyadenilation signal is identified at position 951. Six additional stop codons are observed. A promoter region was revealed containing a putative TATA box located at position −72. Homologous regions were identified between Ara h2, h6, and h7, and between Ara h3 and h4, and between Ara h1P41B and Ara h1P17. The homologous regions will be used for the screening of peanut genomic library to isolate all peanut allergen genes and for down-regulation and silencing of multiple peanut allergen genes. |
| FILED | Monday, November 20, 2000 |
| APPL NO | 09/715036 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 06943021 | Klausner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | MatTek Corporation (Ashland, Massachusetts) |
| INVENTOR(S) | Mitchell Klausner (Sharon, Massachusetts); Seyoum Ayehunie (Natick, Massachusetts); Joseph Kubilus (Dracut, Massachusetts) |
| ABSTRACT | Disclosed is a cervico-vaginal tissue equivalent comprised of vaginal epithelial cells and immune cells, cultured at the air-liquid interface. The tissue equivalent is capable of being infected with a sexually transmitted pathogen such as a virus (e.g., HIV), a bacteria, a helminthic parasite, or a fungus. The tissue equivalent is also capable of undergoing an allergic-type reaction or an irritant-type reaction. The tissue equivalent is characterized as having nucleated basal layer cells and nucleated suprabasal layer cells, and further as having cell layers external to the suprabasal layer progressively increasing in glycogen content and progressively decreasing in nuclei content. Immune cells of the tissue equivalent are primarily located in the basal and suprabasal layers. Also disclosed are methods for producing the tissue equivalent. The methods involve providing vaginal epithelial cells and immune cells, seeding the cells onto a porous support, and co culturing the seeded cells at the air-liquid interface under conditions appropriate for differentiation. One such method disclosed is for generation of the tissue equivalent in serum free medium. Specific cells from which the tissue equivalent is generated, and also specific preferred components of the medium in which the tissue equivalent is generated are provided. Also disclosed is a cervico-vaginal tissue equivalent produced by the methods disclosed herein. |
| FILED | Friday, June 07, 2002 |
| APPL NO | 10/165267 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 06941888 | Barsoum |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roshdy George S. Barsoum (McLean, Virginia) |
| ABSTRACT | A marine vessel which includes a bow section, a stern section and a mid-section, wherein the bow and stern sections are of different hull construction from that of the mid-section which has a curved outer shape; the skin of the hull of the bow and stern sections are preferably made of hybrid composites while the port and starboard sides of the mid-section are of hybrid composites supported on the inside thereof by a light framing to transmit pressure loads; the mid-section further includes an inner section that may be of box beam construction or longitudinal bulkhead construction. |
| FILED | Tuesday, December 16, 2003 |
| APPL NO | 10/735747 |
| ART UNIT | 3617 — Printing/Measuring and Testing |
| CURRENT CPC | Ships 114/356 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 13, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20050913.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page