FedInvent™ Patents
Patent Details for Tuesday, November 08, 2005
This page was updated on Sunday, March 26, 2023 at 07:49 PM GMT
Department of Health and Human Services (HHS)
| US 06962688 | Kozarsky et al. |
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| ASSIGNEE(S) | Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Karen Kozarsky (Philadelphia, Pennsylvania); Attilio Rigotti (Malden, Massachusetts); Monty Krieger (Needham, Massachusetts) |
| ABSTRACT | Methods for regulation of lipid and cholesterol uptake are described which are based on regulation of the expression or function of the SR-BI HDL receptor. The examples demonstrate that estrogen dramatically downregulates SR-BI under conditions of tremendous upregulation of the LDL-receptor. The examples also demonstrate the upregulation of SR-BI in rat adrenal membranes and other non-placental steroidogenic tissues from animals treated with estrogen, but not in other non-placental non-steroidogenic tissues, including lung, liver, and skin. Examples further demonstrate the uptake of fluorescently labeled HDL into the liver cells of animal, which does not occur when the animals are treated with estrogen. Examples also demonstrate the in vivo effects of SR-BI expression on HDL metabolism, in mice transiently overexpressing hepatic SR-BI following recombinant adenovirus infection. Overexpression of the SR-BI in the hepatic tissue caused a dramatic decrease in cholesterol blood levels. These results demonstrate that modulation of SR-BI levels, either directly or indirectly, can be used to modulate levels of cholesterol in the blood. |
| FILED | Monday, August 30, 1999 |
| APPL NO | 09/385799 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962699 | Pojasek et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kevin Pojasek (Cambridge, Massachusetts); Rahul Raman (Cambridge, Massachusetts); Ram Sasisekharan (Bedford, Massachusetts) |
| ABSTRACT | The invention relates to rationally designed polysaccharide lyases and uses thereof. In particular, the invention relates to modified chondroitinase B. The modified chondroitinase B enzymes of the invention are useful for a variety of purposes, including cleaving and sequencing polysaccharides such as glycosaminoglycans (GAGs) as well as removing polysaccharides from a solution. The invention also includes methods of inhibiting anticoagulant activity, inhibiting angiogenesis, treating cancer, and inhibiting maternal malarial infection. |
| FILED | Tuesday, June 03, 2003 |
| APPL NO | 10/454816 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962709 | Koelle et al. |
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| ASSIGNEE(S) | University of Washington, Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | David M. Koelle (Seattle, Washington); Hongbo Chen (Shoreline, Washington); Lawrence Corey (Mercer Island, Washington); Nancy Ann Hosken (Seattle, Washington); Patrick McGowan (Seattle, Washington); Steven P. Fling (Bainbridge Island, Washington); Christine M. Posavad (Seattle, Washington) |
| ABSTRACT | The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are epitopes confirmed to be recognized by T-cells derived from herpetic lesions. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection. |
| FILED | Friday, April 05, 2002 |
| APPL NO | 10/117476 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962785 | Agris et al. |
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| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Paul F. Agris (Raleigh, North Carolina); Salman Ashraf (Raleigh, North Carolina) |
| ABSTRACT | A method of screening for compounds useful for inhibiting retrovirus propagation in a host for the retrovirus, wherein the retrovirus primes reverse transcription in the host by binding of a specific host tRNA to retrovirus RNA at at least a pair of separate binding sites on the host tRNA, comprises contacting the specific host tRNA to the retrovirus RNA in the presence of the test compound, and then determining whether the compound inhibits the binding of the specific host tRNA to the retrovirus RNA in the presence of the test compound. |
| FILED | Tuesday, August 06, 2002 |
| APPL NO | 10/212905 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962786 | Mirkin et al. |
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| ASSIGNEE(S) | Nanosphere, Inc. (Northbrook, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Robert L. Letsinger (Wilmette, Illinois); Robert C. Mucic (Glendale, California); James J. Storhoff (Evanston, Illinois); Robert Elghanian (Chicago, Illinois); Thomas A. Taton (Chicago, Illinois) |
| ABSTRACT | The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids. |
| FILED | Wednesday, April 09, 2003 |
| APPL NO | 10/410324 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962788 | Sheffield et al. |
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| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Val C. Sheffield (Iowa City, Iowa); Kirk Mykytyn (Iowa City, Iowa); Darryl Y. Nishimura (Coralville, Iowa); Edwin M. Stone (Iowa City, Iowa); Charles C. Searby (Iowa City, Iowa) |
| ABSTRACT | The present invention relates to the identification of a gene, mutated at the most common locus now designated BBS1, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities. The human BBS1 protein disclosed herein is composed of 17 exons and spans approximately 23 kb. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described. |
| FILED | Wednesday, May 28, 2003 |
| APPL NO | 10/447322 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962791 | Hultgren et al. |
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| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Siga Pharmaceuticals, Inc. (New York, New York) |
| INVENTOR(S) | Scott Hultgren (Ballwin, Missouri); Meta Kuehn (Berkeley, California); Zheng Xu (Blue Bell, Pennsylvania); Derek Ogg (Uppsala, Sweden); Mark Harris (Uppsala, Sweden); Matti Lepisto (Lund, Sweden); Charles Hal Jones (Saint Louis, Missouri); Jan Kihlberg (Dalby, Sweden) |
| ABSTRACT | Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed. |
| FILED | Wednesday, March 07, 2001 |
| APPL NO | 09/799608 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962798 | Olson et al. |
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| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Eric N. Olson (Dallas, Texas); Da-Zhi Wang (Dallas, Texas) |
| ABSTRACT | The present invention relates to a novel cardiac-specific transcription factor, myocardin. This molecule modulates the development and differentiation of cardiomyocytes and is a potent inhibitor of cell growth. Methods to exploit these observations are provided and include respecifiying non-cardiac cells into cardiac cells, stimulating cardiac tissue regeneration, and methods for treating cardiomyopathies, myocardial infarction. |
| FILED | Friday, December 21, 2001 |
| APPL NO | 10/029217 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962810 | Fraser et al. |
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| ASSIGNEE(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| INVENTOR(S) | Malcolm J. Fraser (Granger, Indiana); Xu Li (Notre Dame, Indiana) |
| ABSTRACT | More efficient transfer of genes into host cells or embryos to transform the cells or embryos is facilitated by transposition vectors using the minimal amount of nucleotide sequences in the transposon piggyBac required for gene transfer. The transformed cells or embryos may be developed into transgenic organisms. |
| FILED | Tuesday, October 30, 2001 |
| APPL NO | 10/001189 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962813 | Pier et al. |
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| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Michael J. Preston (Wellesley, Massachusetts); Lisa Cavacini (Natick, Massachusetts); Marshall Posner (Medfield, Massachusetts) |
| ABSTRACT | The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to P. aeruginosa mucoid exopolysaccharide. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of P. aeruginosa infection and related disorders (e.g., cystic fibrosis). Some antibodies of the invention enhance opsonophagocytic killing of multiple mucoid strains of P. aeruginosa. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides. |
| FILED | Tuesday, May 21, 2002 |
| APPL NO | 10/153437 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962814 | Mitchell et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Shannon Mitchell (Durham, North Carolina); Jennifer Koh (Irvine, California); Vikas Prabhakar (Boston, Massachusetts); Laura Niklason (Hillsborough, North Carolina) |
| ABSTRACT | New methods for producing tissue engineered constructs and engineered native tissues are disclosed. The methods include producing a tissue engineered construct by growing cells in vitro on a substrate and then decellularizing the construct to produce a decellularized construct consisting largely of extracellular matrix components. The construct can be used immediately or stored until needed. The decellularized construct can be used for further tissue engineering, which may include seeding the construct with cells obtained from the intended recipient of the construct. During any of the growth phases required for production of the construct, the developing construct may be subjected to various tissue engineering steps such as application of mechanical stimuli including pulsatile forces. The methods also include producing an engineered native tissue by harvesting tissue from an animal or human, performing one or more tissue engineering steps on the tissue, and subjecting the tissue to decellularization. The decellularized, engineered native tissue may then be subjected to further tissue engineering steps. |
| FILED | Thursday, August 16, 2001 |
| APPL NO | 09/931506 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962891 | Davies et al. |
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| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Huw M. L. Davies (Clarence Center, New York); Tadamichi Nagashima (Allison Park, Pennsylvania) |
| ABSTRACT | Disclosed are dirhodium catalyst compositions. One such dirhodium catalyst composition includes a dirhodium catalyst and a solid support. The dirhodium catalyst includes a Rh—Rh moiety and four bridging ligand moieties. The dirhodium catalyst and the solid support are bound together, but they are not covalently bound together via one or more of the bridging ligand moieties. Another such dirhodium catalyst composition includes a dirhodium tetracarboxylate catalyst and a solid support, and the dirhodium tetracarboxylate catalyst and the solid support are bound together. Yet another such dirhodium catalyst composition includes a dirhodium catalyst and a solid support, where the dirhodium catalyst includes a Rh—Rh moiety and where the dirhodium catalyst and the solid support are bound together via at least one of the rhodiums' axial positions. The compositions can be used in a number of reactions, including insertion reactions (e.g., C—H insertions, Si—H insertions, O—H insertions, and N—H insertions), cyclopropanation reactions, annulations (e.g., [3+2] annulations and [3+4] annulations), and ω,ω-diarylalkanoate synthesis. Methods for making the dirhodium catalyst compositions are also disclosed. |
| FILED | Tuesday, August 27, 2002 |
| APPL NO | 10/229392 |
| ART UNIT | 1755 — Semiconductors/Memory |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962902 | Balasubramanium et al. |
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| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Ambikaipakan Balasubramanium (Cincinnati, Ohio); William T. Chance (Withamsville, Ohio) |
| ABSTRACT | This invention relates generally to dipeptides and tripeptides and to methods for pharmaceutical treatment of mammals using analogs of such dipeptides and tripeptides. More specifically, the invention relates to tripeptides and their analogs, to pharmaceutical compositions containing such dipeptides and tripeptides and to methods of treatment of mammals using such dipeptides and tripeptides. In addition, the invention relates to methods of treatment of mammals using such dipeptides and tripeptides for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm. |
| FILED | Tuesday, May 18, 2004 |
| APPL NO | 10/848469 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962920 | Gangjee |
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| ASSIGNEE(S) | Duquesne University of the Holy Ghost (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | This invention discloses pyrimidine derivatives, and pharmaceutically acceptable salts and prodrugs thereof, useful in therapeutically and/or prophylactically treating patients with an illness. Such illnesses include cancer, and secondary infections caused by Pneumocystis carinii and Toxoplasmosis gondii in immunocompromised patients. The compounds themselves, methods of making these compounds, and methods of using these compounds are all disclosed. |
| FILED | Monday, March 10, 2003 |
| APPL NO | 10/384686 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/260.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962971 | Martins-Green et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Manuela Martins-Green (Riverside, California); Jo Ellen Feugate (Riverside, California); QiJing Li (Riverside, California) |
| ABSTRACT | This invention is based on the discovery that chemokines induce fibroblasts to differentiate to myofibroblasts, which play a critical role in wound healing and are implicated in a number of fibrotic diseases. This activity has been localized to a peptide in the N-terminus of several chemokines. Accordingly, the invention provides polypeptides that induce the differentiation of fibroblasts to myofibroblasts in vitro and in vivo, nucleic acids encoding such polypeptides and related vectors, host cells, and composition containing these components. The invention also encompasses methods for inducing or inhibiting differentiation of fibroblasts to myofibroblasts, in vivo as well as in vitro, and screening methods for identifying other agents that modulate myofibroblast differentiation. |
| FILED | Friday, March 16, 2001 |
| APPL NO | 09/811162 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/329 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962974 | Kalluri |
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| ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | Raghuram Kalluri (Boston, Massachusetts) |
| ABSTRACT | Proteins with anti-angiogenic properties are disclosed, and fragments thereof, and methods of using those proteins and fragments to inhibit or promote angiogenesis. |
| FILED | Friday, July 21, 2000 |
| APPL NO | 09/625191 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962975 | Prusiner |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stanley B. Prusiner (San Francisco, California) |
| ABSTRACT | The invention provides prion protein standards for use as reference materials for prion detection. The standard may be species specific, i.e. the standard is comprised of a preparation for detection of a single strain prion or it may be prepared to allow detection of multiple prion strains simultaneously. The invention also provides methods of preparing the prion protein standards using a group of non-human host mammals which have their genome manipulated with respect to genetic material related to a PrP gene such that the mammals are susceptible to infection with a prion which generally only infects an animal which is genetically diverse from the host. |
| FILED | Wednesday, November 17, 1999 |
| APPL NO | 09/856230 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962987 | Sim et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Kim Lee Sim (Gaithersburg, Maryland); Chetan Chitnis (Washington, District of Columbia); Louis H. Miller (Bethesda, Maryland); David S. Peterson (Rockville, Maryland); Xin-Zhuan Su (Rockville, Maryland); Thomas E. Wellems (Rockville, Maryland) |
| ABSTRACT | The present invention provides isolated polypeptides useful in the treatment and prevention of malaria caused by Plasmodium falciparum or P. vivax. In particular, the polypeptides are derived from the binding domains of the proteins in the EBL family as well as the sialic acid binding protein (SABP) on P. falciparum merozoites. The polypeptides may also be derived from the Duffy antigen binding protein (DABP) on P. vivax merozoites. |
| FILED | Tuesday, May 21, 2002 |
| APPL NO | 10/153273 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962988 | Herr et al. |
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| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | John C. Herr (Charlottesville, Virginia); Scott A. Coonrod (Gordonsville, Virginia); Paul Wright (Staunton, Virginia) |
| ABSTRACT | The present invention relates to proteins that are expressed in oocytes, nucleic acid sequences encoding those proteins and antibodies generated against those proteins. Composition and methods are provided for using the disclosed oocyte proteins as targets for contraceptive drugs. |
| FILED | Friday, January 19, 2001 |
| APPL NO | 10/181612 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962990 | Attarian et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gwynne Attarian (Ann Arbor, Michigan); Kara K. Podkaminer (Jamesville, New York); Sean C. Yoder (Chatsworth, California); Susan A. Kinder Haake (Culver City, California) |
| ABSTRACT | The invention provides origin of replication sequences and replication genes and proteins for a plasmid functional in Fusobacterium (e.g., F. nucleatum) and related species. Provided by the invention are also plasmids and vectors that can replicate in Fusobacterium. Further, the invention provides shuttle vectors that can replicate in Fusobacterium and in other microorganisms, such as E. coli. Still further, the present invention provides host cells comprising the plasmids and shuttle vectors, and methods for transformation of the host cells with the plasmid and shuttle vectors of the invention. |
| FILED | Friday, December 22, 2000 |
| APPL NO | 09/747385 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963653 | Miles |
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| ASSIGNEE(S) | The Research Foundation of the State University of New York (Albany, New York) |
| INVENTOR(S) | Ronald Miles (Newark Valley, New York) |
| ABSTRACT | The invention features a miniature, second-order, microcrystalline silicon microphone diaphragm formed using silicon microfabrication techniques. The diaphragm is composed of two or more rigid diaphragm elements hinged to one another providing second- or higher-order response depending on the number of diaphragm elements used. The response of the differential diaphragm has a response that is highly dependent on the direction of the incident sound. The diaphragms are useful for constructing highly innovative microphones that have far greater directionality, better sensitivity, wider frequency response, and lower noise than is achievable with current technology. |
| FILED | Wednesday, October 22, 2003 |
| APPL NO | 10/691059 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electrical audio signal processing systems and devices 381/424 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963769 | Balaban et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Robert S. Balaban (Bethesda, Maryland); Kathleen M. Ward (Arlington, Virginia); Anthony H. Aletras (Rockville, Maryland) |
| ABSTRACT | A method for obtaining an image by MRI, comprising: administering at least one contrast agent to a subject in amounts effective to perform CEDST MRI analysis; and performing CEDST MRI analysis to produce an image of the subject. A number of different contast agents can be used to practice the present method including, without limitation, sugars, animo acids, nitrogen-containing heterocycles, purines and pyrimidines, nucleosides; imidazole and derivatives thereof, imino acids, barbituric acid and analogs thereof, and miscellaneous materials, such as guanidine hydantoin, parabanic acid, and biologically active salts thereof. |
| FILED | Thursday, April 20, 2000 |
| APPL NO | 09/959138 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 06962092 | Pasquali et al. |
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| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Matteo Pasquali (Houston, Texas); Virginia A. Davis (Webster, Texas); Ingrid Stepanek-Basset (La Grand'Combe, France); A. Nicholas G. Parra-Vasquez (Oxnard, California); Robert H. Hauge (Houston, Texas) |
| ABSTRACT | The present invention is directed to at least one method and at least one apparatus for determining the length of single-wall carbon nanotubes (SWNTs). The method generally comprises the steps of: dispersing a sample of SWNTs into a suitable dispersing medium to form a solvent-suspension of solvent-suspended SWNTs; determining the mean SWNT diameter of the solvent-suspended SWNTs; introducing the solvent-suspended SWNTs into a viscosity-measuring device; obtaining a specific viscosity for the SWNT solvent-suspension; and determining the length of the SWNTs based upon the specific viscosity by solving, for example, the Kirkwood-Auer equation corrected by Batchelor's formula for the drag on a slender cylinder for “L,” to determine the length of the SWNTs. The apparatus generally comprises: a SWNT sample introduction mechanism; a dispersal chamber; a SWNT radius-determination chamber; and a viscosity determining chamber, wherein the SWNT sample introduction mechanism, the dispersal chamber, the SWNT radius-determination chamber, and the viscosity determination chamber are each operatively connected to at least one of the others. |
| FILED | Friday, April 30, 2004 |
| APPL NO | 10/836551 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/866 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962113 | Carlson et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Victor John Carlson (Durango, Colorado); Timothy S. Hennessey (Lothian, Maryland); Mary H. Sherlock (Waldorf, Maryland); Windsor Furr (Laurel, Maryland) |
| ABSTRACT | The present invention comprises a warhead designed to provide a number of spiraling tendrils composed of segmented rods that move in an increasing radial arc in order to defeat a target. The warhead comprises a substantially cylindrical explosive charge having a plurality of rod segments arranged circumferentially around the explosive charge in a plurality of horizontal layers. As the horizontal layers descend down the explosive charge, the rod segments are offset from those directly above and below them to create a pattern that appears to be twisted columns. The number of columns is equivalent to the number of rod segments in each horizontal layer. |
| FILED | Friday, May 09, 2003 |
| APPL NO | 10/436605 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962121 | Kuklinski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert Kuklinski (Portsmouth, Rhode Island) |
| ABSTRACT | A system has a source of gas venting gas at a nose portion of the vehicle to create a gas/vapor cavity on the nose portion and an adjacent hull of the vehicle. A thermal engine propelling the vehicle through ambient water creates waste heat for heating the hull to raise the temperature of the gas/vapor cavity extending over it. A pump aft on the vehicle recirculates a portion of the gas/vapor cavity as recirculated gas to the nose portion. The velocity of the recirculated gas of the gas/vapor cavity is controlled by the pump to be virtually the same as the relative flow rate of the ambient water along an interface boundary between the gas/vapor cavity and the ambient water. |
| FILED | Friday, July 30, 2004 |
| APPL NO | 10/911749 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/67.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962480 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Ly D. Nguyen (Phoenix, Arizona); James L. Hadder (Scottsdale, Arizona); Gregory O. Woodcock (Mesa, Arizona); Stony Kujala (Tempe, Arizona) |
| ABSTRACT | A turbine scroll retention ring may comprise a retainer ring, a plurality of ring fingers, and a plurality of ring joggles. The turbine scroll retention ring may surround and be attached to a radial nozzle. The ring joggles may allow for thermal growth variations between the radial nozzle and the turbine scroll retention ring. The radially outer end portions of the ring fingers may be in contact with a turbine scroll component (for example, an aft scroll ring), such that the turbine scroll retention ring may force contact between the turbine scroll component and the radial nozzle. The finger joggles of the ring fingers may allow for thermal growth variations between the radial nozzle and the turbine scroll component. The turbine scroll retention ring may provide constant axial loading to the aft scroll ring during all engine operating conditions. |
| FILED | Wednesday, November 12, 2003 |
| APPL NO | 10/712434 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962633 | McQuaid |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. McQuaid (Bel Air, Maryland) |
| ABSTRACT | A novel family of amine azides having a cyclic structure therein is disclosed. These compounds have attractive properties as rocket propellants. |
| FILED | Tuesday, March 18, 2003 |
| APPL NO | 10/389885 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Explosive and thermic compositions or charges 149/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962675 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Nathan S. Lewis (La Canada, California); Michael S. Freund (Altadena, California); Shawn M. Briglin (Pasadena, California) |
| ABSTRACT | Methods, systems and sensor arrays are provided implementing techniques for detecting an analyte in a fluid. The techniques include providing a sensor array including at least a first sensor and a second sensor in an arrangement having a defined fluid flow path, exposing the sensor array to a fluid including an analyte by introducing the fluid along the fluid flow path, measuring a response for the first sensor and the second sensor, and detecting the presence of the analyte in the fluid based on a spatio-temporal difference between the responses for the first and second sensors. |
| FILED | Wednesday, August 07, 2002 |
| APPL NO | 10/214794 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/83 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962786 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nanosphere, Inc. (Northbrook, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Robert L. Letsinger (Wilmette, Illinois); Robert C. Mucic (Glendale, California); James J. Storhoff (Evanston, Illinois); Robert Elghanian (Chicago, Illinois); Thomas A. Taton (Chicago, Illinois) |
| ABSTRACT | The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids. |
| FILED | Wednesday, April 09, 2003 |
| APPL NO | 10/410324 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962830 | Behin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Behrang Behin (Berkeley, California); Kam Yin Lau (Danville, California); Richard S. Muller (Kensington, California) |
| ABSTRACT | Microstructure apparatus and methods are described. An exemplary movable microstructure apparatus includes a base, a plate, and a stop. The plate may be coupled to the base through a flexure, so that the plate is movable between a first angular orientation and a second angular orientation. The stop may be configured to contact the bottom portion of the plate in a contact area when the plate is in the second angular orientation. Alternatively, the stop may be configured to contact the plate in a contact area sized so that upon application of an electrostatic bias between the plate and the stop, a sufficient force holds the plate against the stop. Alternatively, the stop may have a substantially planar surface configured to contact the plate in a contact area sized so that, upon application of a force to the plate substantially normal to the substantially planar surface of the stop, a sufficient force holds the plate against the stop such that the plate lies in a plane substantially parallel to the substantially planar surface of the stop. |
| FILED | Wednesday, February 23, 2000 |
| APPL NO | 09/511428 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962831 | Najafi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Khalil Najafi (Ann Arbor, Michigan); Chunbo Zhang (Ann Arbor, Michigan) |
| ABSTRACT | A method of fabricating a thick silicon dioxide layer without the need for long deposition or oxidation and a device having such a layer are provided. Deep reactive ion etching (DRIE) is used to create high-aspect ratio openings or trenches and microstructures or silicon pillars, which are then oxidized and/or refilled with LPCVD oxide or other deposited silicon oxide films to create layers as thick as the DRIE etched depth allows. Thickness in the range of 10-100 μm have been achieved. Periodic stiffeners perpendicular to the direction of the trenches are used to provide support for the pillars during oxidation. The resulting SiO2 layer is impermeable and can sustain large pressure difference. Thermal tests show that such thick silicon dioxide diaphragms or layers can effectively thermally isolate heated structures from neighboring structures and devices within a distance of hundred of microns. Such SiO2 diaphragms or layers of thickness 50-60 μm can sustain an extrinsic shear stress up to 3-5 Mpa. These thick insulating microstructures or layers can be used in thermal, mechanical, fluidic, optical, and bio microsystems. |
| FILED | Wednesday, January 15, 2003 |
| APPL NO | 10/342949 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/52 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963077 | DeHon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); President and Fellows of Harvard College (Cambridge, Massachusetts); Brown University (Providence, Rhode Island); SRI International (Menlo Park, California) |
| INVENTOR(S) | André DeHon (Pasadena, California); Charles M. Lieber (Lexington, Massachusetts); Patrick D. Lincoln (Woodside, California); John E. Savage (Providence, Rhode Island) |
| ABSTRACT | A memory array comprising nanoscale wires is disclosed. The nanoscale wires are addressed by means of controllable regions axially and/or radially distributed along the nanoscale wires. In a one-dimensional embodiment, memory locations are defined by crossing points between nanoscale wires and microscale wires. In a two-dimensional embodiment, memory locations are defined by crossing points between perpendicular nanoscale wires. In a three-dimensional embodiment, memory locations are defined by crossing points between nanoscale wires located in different vertical layers. |
| FILED | Thursday, July 24, 2003 |
| APPL NO | 10/627406 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963122 | Soenen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Barcelona Design, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Eric Soenen (Danville, California); Dan Bui (Sunnyvale, California) |
| ABSTRACT | A capacitive structure is described that comprises a first node and a second node. The first node comprises a first pair of vertically aligned strips that are electrically connected with one or more vias and a second pair of vertically aligned strips that are electrically connected with one or more vias. The higher strips of both of the pairs are at a same metal level and the lower strips of both of the pairs are at a same lower metal level. The second node comprises, at the metal level, a first metal structure having a pair of windows. A first of the windows surround and are isolated from a first of the higher strips. A second of the windows surround and are isolated from a second of the higher strips. The second node also comprises, at the lower metal level, a second metal structure having a pair of windows. A first of the windows surround and are isolated from a first of the lower strips. A second of the windows surround and are isolated from a second of the lower strips. The first and second metal structures are electrically connected with one or more vias. |
| FILED | Friday, September 05, 2003 |
| APPL NO | 10/656793 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/532 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963263 | Cook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Hugh C. Cook (Lynn Haven, Florida); Stephen M. Mahan (Lynn Haven, Florida) |
| ABSTRACT | A non-contact electrical energy transfer system has a nearly continuous loop of ferromagnetic material that defines a gap. A first electric conductor is coiled about a portion of the nearly continuous loop that opposes the gap. A block of the same ferromagnetic material is sized to loosely fit in the gap while being spaced apart from each of the opposing surfaces defining the gap. A second electric conductor is coiled about the block. Electrical energy applied to the first electric conductor induces an electric current in the second electric conductor when the block is positioned in the gap. |
| FILED | Monday, November 03, 2003 |
| APPL NO | 10/699427 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Inductor devices 336/178 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963312 | Schuneman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Nicholas A. Schuneman (Dallas, Texas); James M. Irion, II (Plano, Texas); Richard E. Hodges (Corona, California) |
| ABSTRACT | An antenna apparatus (10) includes an antenna element (12, 412, 512) that has conductive material with a recess therein. The recess includes a balun hole (36, 536), and a tapered slot (37, 537) communicating at its narrow end with the balun hole. The balun hole is approximately rectangular, has a peripheral edge defined by conductive material, and contains air. The tapered slot has a shape which is optimized as a function of factors that include the balun hole design. Each slot edge follows a predetermined curve other than a first-order exponential curve. |
| FILED | Friday, December 14, 2001 |
| APPL NO | 10/022753 |
| ART UNIT | 2821 — Optical Communications |
| CURRENT CPC | Communications: Radio wave antennas 343/767 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963354 | Scheps |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard Scheps (Del Mar, California) |
| ABSTRACT | An image lidar includes a laser for generating light beam pulses in a line scan to illuminate an area surrounding a target. A controller selects pulse width and pulse rate of the light beam pulses emitted by the laser. A photomultiplier tube detects energy from the light beam pulses scattered by the target and generates a series of pixels defined by the light beam pulses and the line scan. A display generates an image from the pixels that is representative of the target. |
| FILED | Thursday, August 07, 1997 |
| APPL NO | 08/908778 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Television 348/31 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963400 | Videen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gorden Videen (Silver Spring, Maryland) |
| ABSTRACT | Methods for analyzing particle systems using polarized scattered light are provided. An exemplary method comprises the steps of: providing models of multiple arbitrary particle systems; performing ray-trace analysis with respect to the models over a range of scatter angles, the ray-trace analysis involving only use of second-order rays; receiving information corresponding to a particle system of interest; and predicting at least one characteristic of the particle system of interest using information generated during the ray-trace analysis. Systems and other methods are provided. |
| FILED | Tuesday, August 19, 2003 |
| APPL NO | 10/642676 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/338 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963442 | Yap et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California); Raytheon Company (Lexington, Massachusetts) |
| INVENTOR(S) | Daniel Yap (Newbury Park, California); Yiu-Man So (West Hills, California) |
| ABSTRACT | A frequency synthesizer for generating a multiple tone lightwave signal that can be converted into an RF carrier or local oscillator signal. The frequency synthesizer comprises a multiple mode master laser, two slave lasers injection-locked to the master laser, an optical coupler coupling the optical outputs of the two slave lasers, which produces an optical heterodyne output. The frequency synthesizer further comprises a homodyne phase-lock loop providing feedback control over one of the slave lasers and a heterodyne phase-lock loop providing feedback control over the other slave laser. A local oscillator selector is used to select the optical mode to which one of the slave lasers is locked, thus providing selection of the frequencies of the heterodyne output. |
| FILED | Wednesday, April 16, 2003 |
| APPL NO | 10/417011 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963653 | Miles |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of the State University of New York (Albany, New York) |
| INVENTOR(S) | Ronald Miles (Newark Valley, New York) |
| ABSTRACT | The invention features a miniature, second-order, microcrystalline silicon microphone diaphragm formed using silicon microfabrication techniques. The diaphragm is composed of two or more rigid diaphragm elements hinged to one another providing second- or higher-order response depending on the number of diaphragm elements used. The response of the differential diaphragm has a response that is highly dependent on the direction of the incident sound. The diaphragms are useful for constructing highly innovative microphones that have far greater directionality, better sensitivity, wider frequency response, and lower noise than is achievable with current technology. |
| FILED | Wednesday, October 22, 2003 |
| APPL NO | 10/691059 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electrical audio signal processing systems and devices 381/424 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963690 | Kassal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James J. Kassal (North Kingstown, Rhode Island); Richard W. Ranlet (North Kingstown, Rhode Island) |
| ABSTRACT | A device for terminating a hybrid electrical/fiber optic cable at a connector comprising a clamp assembly affecting a swage lock on a k-tube to prevent movement of the k-tube within the connector and resultant damage to the optical fibers. The clamp assembly comprises two clamp halves, at least one of which includes a k-tube groove, one or more optical fiber grooves, a fan out cavity, and means for joining the clamp halves. When the clamp halves are joined, the k-tube grooves form an enclosed k-tube channel that is slightly smaller than the outside diameter of the k-tube, thereby creating a swage lock to prevent movement of the k-tube. Similarly, the optical fiber grooves create a swage lock on protective plastic tubes that are placed over the optical fibers as they exit and fan out from the k-tube in the fan out cavity. |
| FILED | Monday, April 26, 2004 |
| APPL NO | 10/834159 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/139 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963875 | Moore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Atomics (San Diego, California) |
| INVENTOR(S) | Reagan W. Moore (San Diego, California); Arcot Rajasekar (Del Mar, California); Chaitanya K. Baru (San Diego, California); Bertram Ludaescher (San Diego, California); Amarnath Gupta (San Diego, California); Richard J. Marciano (San Diego, California) |
| ABSTRACT | A persistent archive of a collection of data objects comprises a self-describing, infrastructure-independent representation of a logical structure for the collection and a self-describing, infrastructure-independent representation of the data objects. The archive is persistent in that it may be instantiated at an indefinite point in time in the future regardless of the state of technology at that time. A knowledge-based persistent archive of a collection of data objects comprises the foregoing two elements but also a self-describing, infrastructure-independent representation of knowledge relevant to the collection. Another embodiment of a knowledge-based persistent archive comprises at least one representation of a collection or the data objects, at least one self-describing, infrastructure-independent, or executable specification of one or more transformations relevant to the collection, and at least one self-describing, infrastructure-independent, or executable specification of one or more rules relevant to the collection. |
| FILED | Wednesday, March 21, 2001 |
| APPL NO | 09/815447 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963915 | Karger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachussetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Karger (Cambridge, Massachusetts); Eric Lehman (Cambridge, Massachusetts); F. Thomson Leighton (Newtonville, Massachusetts); Matthew Levine (Somerville, Massachusetts); Daniel Lewin (Cambridge, Massachusetts); Rina Panagrahy (Mountain View, California) |
| ABSTRACT | The invention relates to a method and apparatus for requesting data from one of a plurality of servers. A virtual network of nodes is generated in response to a data request. A first node on the virtual network of nodes is chosen randomly, and a path generated from the first node to the root on the virtual network. At least one node on the path is mapped to a respective one of the plurality of servers and data is requested from a server. The node may be mapped to the server using the method and apparatus for distributing a request to one of a plurality of resources of the present invention. |
| FILED | Monday, June 03, 2002 |
| APPL NO | 10/161449 |
| ART UNIT | 2145 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06964037 | Pavlovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Kestrel Institute (Palo Alto, California) |
| INVENTOR(S) | Dusko Pavlovic (Palo Alto, California); Douglas R. Smith (Mountain View, California); Junbo Liu (Santa Clara, California) |
| ABSTRACT | A computer-implemented method and system for determining colimits of hereditary diagrams. A user specifies a diagram of diagram and specifies performance of a colimit operation. Once the colimit is performed, the name of the colimit is added to the hereditary diagram. The described embodiment supports diagrams of diagrams, also called hierarchical diagrams. |
| FILED | Tuesday, September 19, 2000 |
| APPL NO | 09/665179 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Software development, installation, and management 717/135 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06962051 | Radcliff |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UTC Power, LLC (South Windsor, Connecticut) |
| INVENTOR(S) | Thomas D. Radcliff (Vernon, Connecticut) |
| ABSTRACT | In a Rankine cycle system wherein a vapor generator receives heat from exhaust gases, provision is made to avoid overheating of the refrigerant during ORC system shut down while at the same time preventing condensation of those gases within the vapor generator when its temperature drops below a threshold temperature by diverting the flow of hot gases to ambient and to thereby draw ambient air through the vapor generator in the process. In one embodiment, a bistable ejector is adjustable between one position, in which the hot gases flow through the vapor generator, to another position wherein the gases are diverted away from the vapor generator. Another embodiment provides for a fixed valve ejector with a bias towards discharging to ambient, but with a fan on the downstream side of said vapor generator for overcoming this bias. |
| FILED | Tuesday, June 17, 2003 |
| APPL NO | 10/463002 |
| ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Power plants 060/597 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962061 | Wilding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Bruce M. Wilding (Idaho Falls, Idaho); Dennis N. Bingham (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho); Terry D. Turner (Ammon, Idaho); Kevin T. Rateman (Idaho Falls, Idaho); Gary L. Palmer (Shelley, Idaho); Kerry M. Klinger (Idaho Falls, Idaho); John J. Vranicar (Concord, California) |
| ABSTRACT | An apparatus and method for producing liquefied natural gas. A liquefaction plant may be coupled to a source of unpurified natural gas, such as a natural gas pipeline at a pressure letdown station. A portion of the gas is drawn off and split into a process stream and a cooling stream. The cooling stream passes through a turbo expander creating work output. A compressor is driven by the work output and compresses the process stream. The compressed process stream is cooled, such as by the expanded cooling stream. The cooled, compressed process stream is divided into first and second portions with the first portion being expanded to liquefy the natural gas. A gas-liquid separator separates the vapor from the liquid natural gas. The second portion of the cooled, compressed process stream is also expanded and used to cool the compressed process stream. Additional features and techniques may be integrated with the liquefaction process including a water clean-up cycle and a carbon dioxide (CO2) clean-up cycle. |
| FILED | Monday, April 14, 2003 |
| APPL NO | 10/414991 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Refrigeration 062/613 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962601 | Becker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago Office of Technology Transfer (Chicago, Illinois) |
| INVENTOR(S) | Lance B. Becker (Chicago, Illinois); Terry Vanden Hoek (Chicago, Illinois); Kenneth E. Kasza (Palos Park, Illinois) |
| ABSTRACT | Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets. |
| FILED | Monday, June 03, 2002 |
| APPL NO | 10/162442 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962683 | Gangwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Santosh K. Gangwal (Cary, North Carolina); Apostolos A. Nikolopoulos (Durham, North Carolina); Mary Anne Dorchak (Morgantown, West Virginia) |
| ABSTRACT | A method is provided for removal of sulfur gases and recovery of elemental sulfur from sulfur gas containing supply streams, such as syngas or coal gas, by contacting the supply stream with a catalyst, that is either an activated carbon or an oxide based catalyst, and an oxidant, such as sulfur dioxide, in a reaction medium such as molten sulfur, to convert the sulfur gases in the supply stream to elemental sulfur, and recovering the elemental sulfur by separation from the reaction medium. |
| FILED | Monday, July 15, 2002 |
| APPL NO | 10/194221 |
| ART UNIT | 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry of inorganic compounds 423/573.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962731 | Propp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Bechtel BWXT Idaho, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | W. Alan Propp (Idaho Falls, Idaho); Mark D. Argyle (Idaho Falls, Idaho); Stuart K. Janikowski (Idaho Falls, Idaho); Robert V. Fox (Idaho Falls, Idaho); William J. Toth (Idaho Falls, Idaho); Daniel M. Ginosar (Idaho Falls, Idaho); Charles A. Allen (Idaho Falls, Idaho); David L. Miller (Idaho Falls, Idaho) |
| ABSTRACT | The present invention is related to the modifying of substrates with multiple modifying agents in a single continuous system. At least two processing chambers are configured for modifying the substrate in a continuous feed system. The processing chambers can be substantially isolated from one another by interstitial seals. Additionally, the two processing chambers can be substantially isolated from the surrounding atmosphere by end seals. Optionally, expansion chambers can be used to separate the seals from the processing chambers. |
| FILED | Tuesday, September 23, 2003 |
| APPL NO | 10/669662 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/430.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962747 | Sasaki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Darryl Y. Sasaki (Albuquerque, New Mexico); Tina A. Waggoner (Rio Rancho, New Mexico); Julie A. Last (Albuquerque, New Mexico) |
| ABSTRACT | The present invention is a self-assembling material comprised of stacks of lipid bilayers formed in a columnar structure, where the assembly process is mediated and regulated by chemical recognition events. The material, through the chemical recognition interactions, has a self-regulating system that corrects the radial size of the assembly creating a uniform diameter throughout most of the structure. The materials form and are stable in aqueous solution. These materials are useful as structural elements for the architecture of materials and components in nanotechnology, efficient light harvesting systems for optical sensing, chemical processing centers, and drug delivery vehicles. |
| FILED | Tuesday, October 23, 2001 |
| APPL NO | 10/041846 |
| ART UNIT | 1775 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Stock material or miscellaneous articles 428/332 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962760 | Rice et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
| INVENTOR(S) | Cynthia Rice (Newington, Connecticut); Xiaoming Ren (Menands, New York); Shimshon Gottesfeld (Niskayuna, New York) |
| ABSTRACT | Methods for conditioning the membrane electrode assembly of a direct methanol fuel cell (“DMFC”) are disclosed. In a first method, an electrical current of polarity opposite to that used in a functioning direct methanol fuel cell is passed through the anode surface of the membrane electrode assembly. In a second method, methanol is supplied to an anode surface of the membrane electrode assembly, allowed to cross over the polymer electrolyte membrane of the membrane electrode assembly to a cathode surface of the membrane electrode assembly, and an electrical current of polarity opposite to that in a functioning direct methanol fuel cell is drawn through the membrane electrode assembly, wherein methanol is oxidized at the cathode surface of the membrane electrode assembly while the catalyst on the anode surface is reduced. Surface oxides on the direct methanol fuel cell anode catalyst of the membrane electrode assembly are thereby reduced. |
| FILED | Thursday, June 12, 2003 |
| APPL NO | 10/460452 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963395 | Goldberg |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth A. Goldberg (Berkeley, California) |
| ABSTRACT | An apparatus and method for at-wavelength EUV mask-blank characterization for inspection of moderate and low spatial frequency coating uniformity using a synchrotron or other source of EUV light. The apparatus provides for rapid, non-destruction, non-contact, at-wavelength qualification of large mask areas, and can be self-calibrating or be calibrated to well-characterized reference samples. It can further check for spatial variation of mask reflectivity or for global differences among masks. The apparatus and method is particularly suited for inspection of coating uniformity and quality and can detect defects in the order of 50 μm and above. |
| FILED | Monday, July 09, 2001 |
| APPL NO | 09/902502 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/237.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963406 | Price et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jeffery R. Price (Knoxville, Tennessee); Philip R. Bingham (Knoxville, Tennessee) |
| ABSTRACT | Systems and methods are described for rapid acquisition of fused off-axis illumination direct-to-digital holography. A method of recording a plurality of off-axis object illuminated spatially heterodyne holograms, each of the off-axis object illuminated spatially heterodyne holograms including spatially heterodyne fringes for Fourier analysis, includes digitally recording, with a first illumination source of an interferometer, a first off-axis object illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; and digitally recording, with a second illumination source of the interferometer, a second off-axis object illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis. |
| FILED | Tuesday, September 03, 2002 |
| APPL NO | 10/234042 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/458 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963816 | Poulsen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Peter Poulsen (Livermore, California) |
| ABSTRACT | A multi-channel spectrometer and a light source are used to measure both the emitted and the reflected light from a surface which is at an elevated temperature relative to its environment. In a first method, the temperature of the surface and emissivity in each wavelength is calculated from a knowledge of the spectrum and the measurement of the incident and reflected light. In the second method, the reflected light is measured from a reference surface having a known reflectivity and the same geometry as the surface of interest and the emitted and the reflected light are measured for the surface of interest. These measurements permit the computation of the emissivity in each channel of the spectrometer and the temperature of the surface of interest. |
| FILED | Tuesday, September 02, 2003 |
| APPL NO | 10/652336 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06962092 | Pasquali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Matteo Pasquali (Houston, Texas); Virginia A. Davis (Webster, Texas); Ingrid Stepanek-Basset (La Grand'Combe, France); A. Nicholas G. Parra-Vasquez (Oxnard, California); Robert H. Hauge (Houston, Texas) |
| ABSTRACT | The present invention is directed to at least one method and at least one apparatus for determining the length of single-wall carbon nanotubes (SWNTs). The method generally comprises the steps of: dispersing a sample of SWNTs into a suitable dispersing medium to form a solvent-suspension of solvent-suspended SWNTs; determining the mean SWNT diameter of the solvent-suspended SWNTs; introducing the solvent-suspended SWNTs into a viscosity-measuring device; obtaining a specific viscosity for the SWNT solvent-suspension; and determining the length of the SWNTs based upon the specific viscosity by solving, for example, the Kirkwood-Auer equation corrected by Batchelor's formula for the drag on a slender cylinder for “L,” to determine the length of the SWNTs. The apparatus generally comprises: a SWNT sample introduction mechanism; a dispersal chamber; a SWNT radius-determination chamber; and a viscosity determining chamber, wherein the SWNT sample introduction mechanism, the dispersal chamber, the SWNT radius-determination chamber, and the viscosity determination chamber are each operatively connected to at least one of the others. |
| FILED | Friday, April 30, 2004 |
| APPL NO | 10/836551 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/866 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962608 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gang Sun (Davis, California); Louise Ko Huang (Hamden, Connecticut) |
| ABSTRACT | The present invention provides durable and regenerable antimicrobial fibers and methods for preparing the same. These fibers have excellent colorfastness and washfastness, and are environmentally friendly. The antimicrobial fibers of this invention are suitable for a variety of purposes, including medical uses, sportswear, and uniforms. |
| FILED | Monday, September 29, 2003 |
| APPL NO | 10/674764 |
| ART UNIT | 1751 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Bleaching and dyeing; fluid treatment and chemical modification of textiles and fibers 08/115.690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962785 | Agris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Paul F. Agris (Raleigh, North Carolina); Salman Ashraf (Raleigh, North Carolina) |
| ABSTRACT | A method of screening for compounds useful for inhibiting retrovirus propagation in a host for the retrovirus, wherein the retrovirus primes reverse transcription in the host by binding of a specific host tRNA to retrovirus RNA at at least a pair of separate binding sites on the host tRNA, comprises contacting the specific host tRNA to the retrovirus RNA in the presence of the test compound, and then determining whether the compound inhibits the binding of the specific host tRNA to the retrovirus RNA in the presence of the test compound. |
| FILED | Tuesday, August 06, 2002 |
| APPL NO | 10/212905 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962891 | Davies et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Huw M. L. Davies (Clarence Center, New York); Tadamichi Nagashima (Allison Park, Pennsylvania) |
| ABSTRACT | Disclosed are dirhodium catalyst compositions. One such dirhodium catalyst composition includes a dirhodium catalyst and a solid support. The dirhodium catalyst includes a Rh—Rh moiety and four bridging ligand moieties. The dirhodium catalyst and the solid support are bound together, but they are not covalently bound together via one or more of the bridging ligand moieties. Another such dirhodium catalyst composition includes a dirhodium tetracarboxylate catalyst and a solid support, and the dirhodium tetracarboxylate catalyst and the solid support are bound together. Yet another such dirhodium catalyst composition includes a dirhodium catalyst and a solid support, where the dirhodium catalyst includes a Rh—Rh moiety and where the dirhodium catalyst and the solid support are bound together via at least one of the rhodiums' axial positions. The compositions can be used in a number of reactions, including insertion reactions (e.g., C—H insertions, Si—H insertions, O—H insertions, and N—H insertions), cyclopropanation reactions, annulations (e.g., [3+2] annulations and [3+4] annulations), and ω,ω-diarylalkanoate synthesis. Methods for making the dirhodium catalyst compositions are also disclosed. |
| FILED | Tuesday, August 27, 2002 |
| APPL NO | 10/229392 |
| ART UNIT | 1755 — Semiconductors/Memory |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06962910 | Brewer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Karen Brewer (Blacksburg, Virginia); Shawn Swavey (Kettering, Ohio) |
| ABSTRACT | The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging π-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen. |
| FILED | Friday, January 31, 2003 |
| APPL NO | 10/355258 |
| ART UNIT | 1614 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/188 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963077 | DeHon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); President and Fellows of Harvard College (Cambridge, Massachusetts); Brown University (Providence, Rhode Island); SRI International (Menlo Park, California) |
| INVENTOR(S) | André DeHon (Pasadena, California); Charles M. Lieber (Lexington, Massachusetts); Patrick D. Lincoln (Woodside, California); John E. Savage (Providence, Rhode Island) |
| ABSTRACT | A memory array comprising nanoscale wires is disclosed. The nanoscale wires are addressed by means of controllable regions axially and/or radially distributed along the nanoscale wires. In a one-dimensional embodiment, memory locations are defined by crossing points between nanoscale wires and microscale wires. In a two-dimensional embodiment, memory locations are defined by crossing points between perpendicular nanoscale wires. In a three-dimensional embodiment, memory locations are defined by crossing points between nanoscale wires located in different vertical layers. |
| FILED | Thursday, July 24, 2003 |
| APPL NO | 10/627406 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963253 | Kovac et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | John M. Kovac (Chicago, Illinois); John E. Carlstrom (Chicago, Illinois) |
| ABSTRACT | A retarder is presented for application in systems that transmit radiation through waveguides, such as microwave or millimeter-wave systems. The retarder is a compound device comprising multiple single element retarders, each of which introduces a retardation phase between different polarization states, and each of which is set at an orientation angle. The phases and angles are selected to maximize the operational bandwidth of the compound retarder. The selection of the phases and angles may be found by solving a set of simultaneous equations. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/369154 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/21.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963604 | Erdogmus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Deniz Erdogmus (Gainesville, Florida); Marcelino Lazaro (Madrid, Spain); Jose Carlos Principe (Gainesville, Florida); Ignacio Santamaria (Cantabria, Spain) |
| ABSTRACT | An iterative method of equalizing an input signal received over a digital communication channel can include (a) using a kernel density estimate where different values of a kernel size are indicative of either a blind or a decision-directed equalization mode, (b) processing a received signal using a blind equalization mode, and (c) evaluating, on a block or sample basis, an error measure based on a distance among a distribution of an equalizer output and a constellation. The method also can include (d) updating the kernel size based upon the error measure thereby facilitating automatic switching between the blind and decision-directed equalization modes, where the kernel size is initially set to a value indicative of the blind equalization mode. The method additionally can include (e) selectively applying blind equalization or decision-directed equalization to the input signal according to the updated kernel size for subsequent iterations of steps (c)-(e). |
| FILED | Wednesday, March 31, 2004 |
| APPL NO | 10/814448 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/232 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963824 | Davidson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph K. Davidson (Tempe, Arizona); Jami J. Shah (Scottsdale, Arizona); Amir Mujezinovié (Guilderland, New York) |
| ABSTRACT | The objective of the invention is a bi-level method for modeling geometric tolerances compatible with the ANSI/ASME tolerance standard. At the local level, the model represents each tolerance-zone for a plane or an axis (line) as a tolerance map, and it includes the computational techniques that relate interdependencies between these regions and subregions within them. The model includes formulations for variations in size, form, orientation, position, and runout, and combinations of these, because all of these variations can be modeled using points, lines, and planes. Since variations in simple profiles that are formed from lines and circular arcs also can be described by such combinations, they too are includable in the formulation. The primary method is to overlay the geometry of tolerance-zones onto some traditional modes for representing planes, lines, and points. At the global level, the model inter-relates all frames of reference on a part or an assembly. |
| FILED | Friday, February 18, 2000 |
| APPL NO | 09/507542 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963915 | Karger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachussetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Karger (Cambridge, Massachusetts); Eric Lehman (Cambridge, Massachusetts); F. Thomson Leighton (Newtonville, Massachusetts); Matthew Levine (Somerville, Massachusetts); Daniel Lewin (Cambridge, Massachusetts); Rina Panagrahy (Mountain View, California) |
| ABSTRACT | The invention relates to a method and apparatus for requesting data from one of a plurality of servers. A virtual network of nodes is generated in response to a data request. A first node on the virtual network of nodes is chosen randomly, and a path generated from the first node to the root on the virtual network. At least one node on the path is mapped to a respective one of the plurality of servers and data is requested from a server. The node may be mapped to the server using the method and apparatus for distributing a request to one of a plurality of resources of the present invention. |
| FILED | Monday, June 03, 2002 |
| APPL NO | 10/161449 |
| ART UNIT | 2145 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06963291 | Holforty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Wendy L. Holforty (Mountain View, California); J. David Powell (Half Moon Bay, California) |
| ABSTRACT | A dynamic wake avoidance system utilizes aircraft and atmospheric parameters readily available in flight to model and predict airborne wake vortices in real time. A novel combination of algorithms allows for a relatively simple yet robust wake model to be constructed based on information extracted from a broadcast. The system predicts the location and movement of the wake based on the nominal wake model and correspondingly performs an uncertainty analysis on the wake model to determine a wake hazard zone (no fly zone), which comprises a plurality of “wake planes,” each moving independently from another. The system selectively adjusts dimensions of each wake plane to minimize spatial and temporal uncertainty, thereby ensuring that the actual wake is within the wake hazard zone. The predicted wake hazard zone is communicated in real time directly to a user via a realistic visual representation. In an example, the wake hazard zone is visualized on a 3-D flight deck display to enable a pilot to visualize or “see” a neighboring aircraft as well as its wake. The system substantially enhances the pilot's situational awareness and allows for a further safe decrease in spacing, which could alleviate airport and airspace congestion. |
| FILED | Thursday, May 15, 2003 |
| APPL NO | 10/440491 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Communications: Electrical 340/945 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963993 | Semancik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Susan K. Semancik (Snow Hill, Maryland); Annette M. Conger (Snow Hill, Maryland) |
| ABSTRACT | The present invention provides a fail-over file transfer process to handle data file transfer when the transfer is unsuccessful in order to avoid unnecessary network congestion and enhance reliability in an automated data file transfer system. If a file cannot be delivered after attempting to send the file to a receiver up to a preset number of times, and the receiver has indicated the availability of other backup receiving locations, then the file delivery is automatically attempted to one of the backup receiving locations up to the preset number of times. Failure of the file transfer to one of the backup receiving locations results in a failure notification being sent to the receiver, and the receiver may retrieve the file from the location indicated in the failure notification when ready. |
| FILED | Friday, September 28, 2001 |
| APPL NO | 09/965248 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 06962810 | Fraser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| INVENTOR(S) | Malcolm J. Fraser (Granger, Indiana); Xu Li (Notre Dame, Indiana) |
| ABSTRACT | More efficient transfer of genes into host cells or embryos to transform the cells or embryos is facilitated by transposition vectors using the minimal amount of nucleotide sequences in the transposon piggyBac required for gene transfer. The transformed cells or embryos may be developed into transgenic organisms. |
| FILED | Tuesday, October 30, 2001 |
| APPL NO | 10/001189 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 06963291 | Holforty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Wendy L. Holforty (Mountain View, California); J. David Powell (Half Moon Bay, California) |
| ABSTRACT | A dynamic wake avoidance system utilizes aircraft and atmospheric parameters readily available in flight to model and predict airborne wake vortices in real time. A novel combination of algorithms allows for a relatively simple yet robust wake model to be constructed based on information extracted from a broadcast. The system predicts the location and movement of the wake based on the nominal wake model and correspondingly performs an uncertainty analysis on the wake model to determine a wake hazard zone (no fly zone), which comprises a plurality of “wake planes,” each moving independently from another. The system selectively adjusts dimensions of each wake plane to minimize spatial and temporal uncertainty, thereby ensuring that the actual wake is within the wake hazard zone. The predicted wake hazard zone is communicated in real time directly to a user via a realistic visual representation. In an example, the wake hazard zone is visualized on a 3-D flight deck display to enable a pilot to visualize or “see” a neighboring aircraft as well as its wake. The system substantially enhances the pilot's situational awareness and allows for a further safe decrease in spacing, which could alleviate airport and airspace congestion. |
| FILED | Thursday, May 15, 2003 |
| APPL NO | 10/440491 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Communications: Electrical 340/945 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 06963875 | Moore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Atomics (San Diego, California) |
| INVENTOR(S) | Reagan W. Moore (San Diego, California); Arcot Rajasekar (Del Mar, California); Chaitanya K. Baru (San Diego, California); Bertram Ludaescher (San Diego, California); Amarnath Gupta (San Diego, California); Richard J. Marciano (San Diego, California) |
| ABSTRACT | A persistent archive of a collection of data objects comprises a self-describing, infrastructure-independent representation of a logical structure for the collection and a self-describing, infrastructure-independent representation of the data objects. The archive is persistent in that it may be instantiated at an indefinite point in time in the future regardless of the state of technology at that time. A knowledge-based persistent archive of a collection of data objects comprises the foregoing two elements but also a self-describing, infrastructure-independent representation of knowledge relevant to the collection. Another embodiment of a knowledge-based persistent archive comprises at least one representation of a collection or the data objects, at least one self-describing, infrastructure-independent, or executable specification of one or more transformations relevant to the collection, and at least one self-describing, infrastructure-independent, or executable specification of one or more rules relevant to the collection. |
| FILED | Wednesday, March 21, 2001 |
| APPL NO | 09/815447 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 06964037 | Pavlovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Kestrel Institute (Palo Alto, California) |
| INVENTOR(S) | Dusko Pavlovic (Palo Alto, California); Douglas R. Smith (Mountain View, California); Junbo Liu (Santa Clara, California) |
| ABSTRACT | A computer-implemented method and system for determining colimits of hereditary diagrams. A user specifies a diagram of diagram and specifies performance of a colimit operation. Once the colimit is performed, the name of the colimit is added to the hereditary diagram. The described embodiment supports diagrams of diagrams, also called hierarchical diagrams. |
| FILED | Tuesday, September 19, 2000 |
| APPL NO | 09/665179 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Software development, installation, and management 717/135 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 06963827 | Elyea et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Larry L. Elyea (Centreville, Virginia); John W. Brown (Manassas, Virginia); David J. Aubin (Center Harbor, New Hampshire); Vance J. Cathell (Fairfax, Virginia) |
| ABSTRACT | A method and apparatus for performing discrete simulation of ergonomic movements that includes a microprocessor to transform a manually performed process into a time-based listing of events, simulate the process and tabulate the results. In addition to a tabular output of the simulation results, the present system provides a graphical representation of a subject performing the simulated tasks together with color-coded depictions illustrating awkward and overly-demanding body movements. Furthermore, an event detector is provided to detect invalid events that may be simulated during verification of the design. The entire process is performed in a manner that minimizes data transfer time between the simulated and graphical portions thereby ensuring that a high level of synchronization is maintained between the simulation of the process and creation of the graphical representation. |
| FILED | Friday, September 29, 2000 |
| APPL NO | 09/675256 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 06962573 | Wilcox |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Wilcox (Colorado Springs, Colorado) |
| ABSTRACT | A tube for implantation into the eye for replacement conduction of aqueous humor from the chambers of the eyeball to the subconjunctival tissue and ultimately to the venous system is comprised of an elongated fluid conducting conduit having distal and proximate ends, a sidewall and an interior passageway and at least one longitudinally extending opening in the sidewall that exposes the interior passageway and at least one nidi-forming structure carried by the conduit and extending laterally therefrom to implement the formation of at least one aqueous filtration bleb in the tissue of the eyeball. In one embodiment, the tube also contains at least one releasable ligature circumscribing the conduit. In another embodiment, the tube also contains an anchor appended to the conduit to prevent it from migrating from its placement site. |
| FILED | Wednesday, October 18, 2000 |
| APPL NO | 09/691671 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06963626 | Shaeffer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | K. Derek Shaeffer (Menlo Park, California); Theresa H. Meng (Portola Valley, California); Thomas H. Lee (Cupertino, California); Sydney Reader (Stanford, California) |
| ABSTRACT | A communication system uses analog and digital circuits along the same data path in a manner that permits the analog circuitry to avoid adverse affects caused by the digital circuitry. Consistent with one embodiment directed to a signal processing system that detects faint incoming signals, the analog and digital circuits are implemented on a single piece of silicon. In such signal processing systems, noise generated by digital processing blocks can degrade the performance of sensitive analog portions. The effective noise is reduced by causing the analog and digital portions of the system to function during separate time intervals. The noise-generating portions of the system may then be turned off during a first data-communication interval while the analog block operates. The data acquired during this period is stored for subsequent processing by the digital portion during a second shorter data-communication interval. Other aspects are applicable to reception arrangements in which part of the incoming signal may be disregarded without significant degradation in performance of the rest of the system, and other aspects are directed to transmission arrangements in which the inverse of the above reception arrangement is used. |
| FILED | Wednesday, May 12, 1999 |
| APPL NO | 09/310598 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Pulse or digital communications 375/346 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 08, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20051108.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page