FedInvent™ Patents
Patent Details for Tuesday, December 13, 2005
This page was updated on Sunday, March 26, 2023 at 07:50 PM GMT
Department of Defense (DOD)
| US 06974197 | Henry et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charles E. Henry (Joppa, Maryland); Monica J. Heyl (Joppa, Maryland); Dennis J. Reutter (Churchville, Maryland) |
| ABSTRACT | A portable containment system includes a glovebox apparatus, a self-contained filter unit, and removable conduits extending therebetween. The glovebox apparatus includes a first module for releasably covering a first sidewall opening. The first module, which has body and flange portions, has a storage position where the body portion is positioned through the first sidewall opening into the glovebox interior and an operative position where the body portion is positioned exterior of the glovebox. The glovebox apparatus includes second modules for releasably covering a second sidewall opening where the second modules are smaller than the first sidewall opening for inserting the second modules into the interior of the glovebox for storage. The filter unit includes a plurality of gas filters, an air pump, and detectors for monitoring the air flow through the system. |
| FILED | Monday, April 05, 2004 |
| APPL NO | 10/825802 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Supports: Cabinet structure 312/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974249 | Fair et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Geoff E. Fair (Centerville, Ohio); Triplicane A. Parthasarathy (Beavercreek, Ohio); Ronald J. Kerans (Yellow Springs, Ohio) |
| ABSTRACT | An improved thermal history sensor having multiple glass ceramic substrates with unique compositions is disclosed. By positioning the sensor adjacent to a component subject to thermal stressors, each of the glass ceramic substrates react with a different rate of nucleation and crystal growth and thus yield a specific measure of opacity. By comparing these values representing the opacity for each glass ceramic substrate, or thermal history fingerprint, to baseline data, information about the expected remaining useful lifetime of the component may be obtained. |
| FILED | Wednesday, March 17, 2004 |
| APPL NO | 10/801294 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/102 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974356 | Hobson et al. |
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| ASSIGNEE(S) | Nekton Research LLC (Durham, North Carolina) |
| INVENTOR(S) | Brett W. Hobson (Carmel, California); Mathieu Kemp (Durham, North Carolina); Ryan Moody (Raleigh, North Carolina); Charles A. Pell (Durham, North Carolina); Frederick Vosburgh (Durham, North Carolina) |
| ABSTRACT | Devices for navigating in a fluid medium having a solid boundary include a vehicle body and a fin attached to the vehicle body. The fin is configured to oscillate relative to the body such that interaction between the fin and the fluid medium produces propulsive forces that propel the vehicle body in a desired direction in the fluid medium. The fin is also configured to rotate relative to the body along a transverse axis such that engagement between the fin and the solid boundary propels the vehicle body in a desired direction on the solid boundary. |
| FILED | Tuesday, May 18, 2004 |
| APPL NO | 10/848330 |
| ART UNIT | 3617 — Optics |
| CURRENT CPC | Marine propulsion 440/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974507 | DeLuca |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Daniel P. DeLuca (Hebron, Connecticut) |
| ABSTRACT | A damage tolerant microstructure for a lamellar alloy, such as a lamellar γTiAl alloy, is provided in accordance with the present invention. The alloy comprises a matrix and a plurality of grains or lamellar colonies, a portion of which exhibit a nonplanar morphology within said matrix. Each of the lamellar colonies contains a multitude of lamella with irregularly repeating order. The γTiAl platelets have a triangular (octahedral) unit cell and stack with γ twins. The α2Ti3Al platelets are irregularly interspersed. The unit cell for α2Ti3Al is hexagonal. Each of the layers has a curved, nonplanar structure for resisting crack formation and growth. |
| FILED | Monday, March 03, 2003 |
| APPL NO | 10/378171 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Metal treatment 148/421 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974526 | Lee et al. |
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| ASSIGNEE(S) | Calibrant Biosystems, Inc. (Rockville, Maryland); The University of Maryland (Riverdale, Maryland) |
| INVENTOR(S) | Cheng Sheng Lee (Ellicott City, Maryland); Don DeVoe (Bethesda, Maryland) |
| ABSTRACT | The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins and other biomolecules. According to another aspect of the invention, an isoelectric point based separation is enabled in a first dimension, and a size based separation in a second dimension. |
| FILED | Wednesday, May 01, 2002 |
| APPL NO | 10/135386 |
| ART UNIT | 1753 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/451 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974604 | Hunter et al. |
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| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Andrew T. Hunter (Woodland Hills, California); Peter D. Brewer (Westlake Village, California) |
| ABSTRACT | A method for assembling components on a substrate including the steps of: (a) selectively coating at least a first receptor site of the substrate with a liquid precursor that forms a solid adhesive upon contact with an initiator; (b) providing each of the components with an adhesion surface that has the initiator; and (c) depositing the components on the substrate in a manner that causes a first of the components to contact the at least first receptor site whereupon contact between the initiator and the liquid precursor causes formation of the adhesive which affixes the first compound to the first receptor site. In a preferred embodiment of the invention, the precursor is a liquid monomer and the initiator initiates a polymerization reaction upon contact with the monomer to form a solid polymer. |
| FILED | Monday, August 12, 2002 |
| APPL NO | 10/218053 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974637 | Pfaendtner et al. |
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| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jeffrey Allan Pfaendtner (Blue Ash, Ohio); Deborah A. Schorr (Cincinnati, Ohio); Ramgopal Darolia (West Chester, Ohio); Joseph David Rigney (Milford, Ohio); Irene Spitsberg (Loveland, Ohio); William Scott Walston (Mason, Ohio) |
| ABSTRACT | An article and TBC coating system thereon that in combination exhibit significantly improved spallation resistance. The article comprises a substrate formed of a metal alloy containing ruthenium and one or more refractory elements (e.g., tantalum, tungsten, molybdenum, rhenium, hafnium, etc.). The substrate is protected by a coating system comprising an aluminum-containing bond coat on the surface of the substrate and a ceramic coating bonded to the substrate by the bond coat. The bond coat, preferably an aluminide, is deposited so as to be substantially free of ruthenium, though ruthenium is present in the bond coat as a result of diffusion from the substrate into the bond coat. |
| FILED | Friday, December 19, 2003 |
| APPL NO | 10/707543 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/632 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974640 | Gell et al. |
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| ASSIGNEE(S) | The University of Connecticut (Storrs, Connecticut) |
| INVENTOR(S) | Maurice Gell (Newington, Connecticut); Tongsan D. Xiao (Willington, Connecticut); Leon Shaw (Willington, Connecticut); Eric Jordan (Storrs, Connecticut); Xiangliang Jiang (Changsha, China PRC) |
| ABSTRACT | A contiguous duplex microstructured material comprises a nanostructured material having two structural states, for example, a duplex microstructured coating. One state comprises substantially nanostructured features, while the second state substantially comprises microstructured features. A duplex nanostructured coating can be made by thermal spraying a reconstituted nanostructured material onto a substrate under conditions effective to form a coating comprising more than one structural state. |
| FILED | Tuesday, July 09, 2002 |
| APPL NO | 10/191977 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/701 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974801 | Honda et al. |
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| ASSIGNEE(S) | The Trustees of Dartmounth College (Hanover, New Hampshire) |
| INVENTOR(S) | Tadashi Honda (Hanover, New Hampshire); Yukiko Honda (Hanover, New Hampshire); Gordon W. Gribble (Lebanon, New Hampshire); Michael B. Sporn (Tunbridge, Vermont); Nanjoo Suh (White River Junction, Vermont) |
| ABSTRACT | New triterpenoid derivatives with various substituents at the C-17 position of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) were synthesized. Among them, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile (CNDDO), 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl) imidazole, 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl)-2-methylimidazole, 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl)-4-methylimidazole show extremely high inhibitory activity (IC50=0.01-1 pM level) against production of nitric oxide induced by interferon-γ in mouse macrophages. These compounds can be used in the prevention or treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, rheumatoid arthritis, and other inflammatory diseases. All the new triterpenoid derivatives are more potent than previously known CDDO. |
| FILED | Monday, May 12, 2003 |
| APPL NO | 10/435925 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974857 | Baek et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Jong-Beom Baek (Cheongju, South Korea); Loon-Seng Tan (Centerville, Ohio) |
| ABSTRACT | An end-capped quinoxaline-containing hyperbranched ether-ketone polymer having repeating units of the formula: wherein n represents the degree of polymerization for the parent hyperbranched polymer, x represents the degree of endgroup functionalization, x has a value of 0.05 to 1.0, and G is selected from the group consisting of and alkyl having 2 to 16 carbon atoms, and a method for preparing the polymer are provided. |
| FILED | Monday, December 08, 2003 |
| APPL NO | 10/729563 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 528/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975134 | Kuang et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Jente B. Kuang (Austin, Texas); Hung C. Ngo (Austin, Texas); Kevin J. Nowka (Round Rock, Texas) |
| ABSTRACT | A buffer/driver having large output devices for driving multiple loads is configured with three parallel paths. The first logic path is made of small devices and is configured to provide the logic function of the buffer/driver without the ability to drive large loads. Second and third logic paths have the logic function of the first logic path up to the last inverting stage. The last inverting stage in each path is a single device for driving the logic states of the buffer output. The second and third logic paths have power-gating that allows the input to the pull-up and pull-down devices to float removing gate-leakage voltage stress. When the second and third logic paths are power-gated, the first logic path provides a keeper function to hold the logic state of the buffer output. The buffer/driver may be an inverter, non-inverter, or provide a multiple input logic function. |
| FILED | Thursday, April 08, 2004 |
| APPL NO | 10/821048 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Electronic digital logic circuitry 326/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975178 | Kessler et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Donald J. Kessler (Beavercreek, Ohio); David N. Coates (Dayton, Ohio) |
| ABSTRACT | A military special operations forces communications assisting, ruggedized, manually operated coaxial antenna A/B switch especially suited for mounting directly on the input/output port connector of a wide band transceiver radio apparatus or for alternate use as a tether-connected switch. The switch includes multi-switch stacking capability, weather and rough usage adaptability, detented operation, accidental position change protection, gloved hand operation and desirable electrical characteristics. Use of the switch in single or multi switch arrangements under darkened and time-limited battlefield conditions to change between differing antennas used with a military mission transceiver radio transceiver is possible. |
| FILED | Wednesday, June 25, 2003 |
| APPL NO | 10/608114 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975281 | Neel |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael M. Neel (Ridgecrest, California) |
| ABSTRACT | A spiral antenna having a pair of antenna arms mounted on a dielectric substrate. A balun is included to connect the antenna which has an impedance of 100 ohms to a 50 ohm cable. Unique features of the spiral antenna design provide for size reduction at a given lowest required frequency of operation. The spiral antenna has dielectric material layers positioned on both side of the antenna's metal arms. In addition, the antenna input impedance is reduced from the normal 100 ohm input impedance to approximately 50 ohms due the dielectric material. |
| FILED | Friday, April 30, 2004 |
| APPL NO | 10/839447 |
| ART UNIT | 2821 — Optical Communications |
| CURRENT CPC | Communications: Radio wave antennas 343/895 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975555 | Lu et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Yu Lu (Hopewell Junction, New York); William Robert Reohr (Ridgefield, Connecticut); Roy Edwin Scheuerlein (Cupertino, California) |
| ABSTRACT | A magnetic random access memory circuit comprises a plurality of magnetic memory cells, each of the memory cells including a magnetic storage element having an easy axis and a hard axis associated therewith, and a plurality of column lines and row lines for selectively accessing one or more of the memory cells, each of the memory cells being proximate to an intersection of one of the column lines and one of the row lines. Each of the magnetic memory cells is arranged such that the easy axis is substantially parallel to a direction of flow of a sense current and the hard axis is substantially parallel to a direction of flow of a write current. |
| FILED | Friday, October 29, 2004 |
| APPL NO | 10/976598 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/230.70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975682 | Cosand |
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| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Albert E. Cosand (Agoura Hills, California) |
| ABSTRACT | A quantizer adapted for use with a delta-sigma analog-to-digital converter. The quantizer includes first and second comparators adapted to compare an input analog signal to a threshold and provide a digital output in response thereto. First and second thresholds are provided to the first and second comparators respectively. In accordance with the present teachings, a mechanism is provided for changing the thresholds to minimize conversion errors. While the mechanism for changing the thresholds may be implemented with resistive and/or capacitive ladders, in the illustrative embodiment, digital-to-analog converters are utilized. The DACs are driven by error shaping logic. The inventive quantizer allows for an improved delta-sigma analog-to-digital converter design which combines an ADC and a DAC. The DAC reconstructs the analog equivalent of the digital output of the ADC. The ADC is a flash converter consisting of one comparator per threshold. The DAC operates by summing the outputs of a set of nominally identical unit elements. The DAC has the same number of elements as there are comparators in the flash ADC and each comparator drives one element of the DAC. A novel feature is that the thresholds of the comparators in the ADC can individually be dynamically adjusted, so that the correspondence between an element of the DAC and a particular threshold of the ADC can be varied from sample to sample under the control of logic circuitry. This arrangement allows the correspondence between DAC elements and ADC thresholds to be remapped without introducing any additional delay into the signal path between the ADC and the DAC. In a high speed continuous-time delta sigma modulator, this allows randomization or shaping of the mismatch errors of the DAC elements to be achieved without incurring any penalty in sample rate, nor adding any excess delay into the loop that might destabilize or otherwise degrade the operation of the modulator. |
| FILED | Tuesday, June 12, 2001 |
| APPL NO | 09/879470 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/247 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975690 | Lin et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | David M. Lin (Beavercreek, Ohio); James B. Y. Tsui (Dayton, Ohio) |
| ABSTRACT | A simplified, weak GPS C/A code coherent acquisition method. When performing GPS signal acquisition, the strength of a signal received at a GPS receiver having an outside antenna is generally sufficiently strong such that only 1 ms of data needs to be used in acquisition to find the signal. However, for weak signals received at a GPS receiver, when the antenna is inside a building or vehicle, for example, a long record of data is needed for acquisition. The present invention reduces the calculation burden for GPS signal acquisition for a weak signal. |
| FILED | Wednesday, August 15, 2001 |
| APPL NO | 09/929720 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975752 | Dixon et al. |
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| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Walter Vincent Dixon (Delanson, New York); Nick Andrew Van Stralen (Ballston Lake, New York); Robert Gideon Wodnicki (Schenectady, New York) |
| ABSTRACT | An imaging system includes a programmable detector framing node controlling generation of radiation and controlling radioscopic image detection. Radioscopic image data is acquired and communicated independently of a host computer operating system. The detector framing node controls events in real time according to an event instruction sequence and communicates received radioscopic image data to host memory through a computer communication bus. Image data is received from a selected flat panel detector of a plurality of different flat panel detectors. The image data is selectively reordered according to parameters of the selected flat panel detector before communication to host memory. |
| FILED | Wednesday, January 31, 2001 |
| APPL NO | 09/774549 |
| ART UNIT | 2625 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975802 | Maki et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Paul A. Maki (Harvard, Massachusetts); Susan C. Palmateer (Harvard, Massachusetts) |
| ABSTRACT | A method for fabricating electromagnetic waveguides. The primary expected application is for the formation of dielectric type waveguides suitable for the confinement and guidance of intra-red and visible wavelengths. A secondary application is the formation of waveguides which can be filled with liquids or gases. The method uses standard microelectronic processing techniques. |
| FILED | Thursday, May 26, 2005 |
| APPL NO | 11/136802 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/129 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975939 | Edwards et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel L. Edwards (Manassas, Virginia); R. Justin Simpson (Bethesda, Maryland) |
| ABSTRACT | Time-tagged coordinates from session-unique transmissions of wireless devices are collected routinely and stored for later analysis. From this data, one may derive a sequence of wireless device operation from which attributes may be ascertained. Sequences are accumulated until a dense aggregate pattern (900) is formed over a geographic area. Aggregate data is sorted into ranges representing speed of movement and then converted to pixels representing cells (401) in an aggregate matrix (400). Heavily weighted values (402) are assigned to cells (401) that represent a location within a pre-specified spatial error (100) about a data point (101). Lower values are assigned to cells (401) representing paths (200), or corridors, connecting these better-identified locations. As more transmission sessions (500) are added to the matrix (400), the largest weight values (402) cluster as individual cells (401) representing a most likely path (1001). Thus precise topographic attributes may be derived based on these spatial clusters (FIG. 11A), overlapping paths connecting them (1001), or combinations (FIG. 15A) thereof. |
| FILED | Monday, July 29, 2002 |
| APPL NO | 10/206757 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975972 | Vreugdenhil et al. |
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| ASSIGNEE(S) | Synopsys, Inc. (Mountain View, California) |
| INVENTOR(S) | Gordon J. Vreugdenhil (Beaverton, Oregon); Ernst Christen (Beaverton, Oregon); Martin Vlach (Portland, Oregon) |
| ABSTRACT | In simulating a physical circuit or system including analog and mixed signal digital-analog components, a computer models the physical circuit or system as a system of simultaneous equations. Conditional equations with associated conditions that can be true or false at different analog solution iterations result in a system of simultaneous equations that can change during the simulation. Rather than reformulating the system of simultaneous equations at each analog solution iteration, the system of simultaneous equations includes slots that are associated with conditional equations as the conditional equations become active. At a given point during the simulation, the conditions associated with the conditional equations are evaluated to determine which conditional equations are active. The values of the active conditional equations are placed in the slots in the system of simultaneous equations. System variables are associated with active conditional equations. The system of simultaneous equations is then solved to determine the values of the system variables. If there are additional analog solution iterations, the active conditional equations can change, and different conditional equations can be associated with each of the slots in the system of simultaneous equations. Once the simulation is complete, the results of the simulation (i.e., the values of the variables in the simulation model) can be used to analyze the behavior of the physical circuit or system. |
| FILED | Thursday, June 08, 2000 |
| APPL NO | 09/590796 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06976168 | Branstad et al. |
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| ASSIGNEE(S) | McAfee, Inc. (Santa Clara, California) |
| INVENTOR(S) | Dennis K. Branstad (Austin, Texas); David W. Carman (Glenwood, Maryland) |
| ABSTRACT | A system and method for implementing adaptive cryptographically synchronized authentication is disclosed. The authentication system includes a controller that dynamically selects one of a plurality of authentication mechanisms to be used in providing authentication for an exchange of message data. The variation in the level of authentication assurance can be based on one or more factors such as the current security conditions and the available CPU utilization. |
| FILED | Friday, July 21, 2000 |
| APPL NO | 09/621060 |
| ART UNIT | 2134 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 06974254 | Paliwal et al. |
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| FUNDED BY |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Bhudatt R. Paliwal (Madison, Wisconsin); Wolfgang Tome (Madison, Wisconsin) |
| ABSTRACT | A volume phantom for radiation therapy verification employs film held in a spiral configuration within a equalizing ring of attenuating material. The ring provides improved uniformity in radiation measurement and may be extended, for example, to a hemisphere to provide improved modeling and simulation of treatments in the region of the head. |
| FILED | Wednesday, June 12, 2002 |
| APPL NO | 10/171137 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974526 | Lee et al. |
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| ASSIGNEE(S) | Calibrant Biosystems, Inc. (Rockville, Maryland); The University of Maryland (Riverdale, Maryland) |
| INVENTOR(S) | Cheng Sheng Lee (Ellicott City, Maryland); Don DeVoe (Bethesda, Maryland) |
| ABSTRACT | The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array of second dimension microchannels extending in a second direction, preferably, orthogonal to the first dimension. The ends of at least some of the microchannels are in fluid communication with a plurality of reservoirs. The substrates may further include a number of microchannels and reservoirs. The reservoirs are in electrical communication with a plurality of electrodes and voltage power sources. The device enables two dimensional separations of proteins and other biomolecules. According to another aspect of the invention, an isoelectric point based separation is enabled in a first dimension, and a size based separation in a second dimension. |
| FILED | Wednesday, May 01, 2002 |
| APPL NO | 10/135386 |
| ART UNIT | 1753 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/451 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974533 | Zhou |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Dao Min Zhou (Saugus, California) |
| ABSTRACT | An improved electrode and method for manufacturing the improved electrode wherein the electrode having a fractal surface coating of platinum [which the present inventor refers to as “platinum gray”] with a increase in surface area of at least 5 times when compared to shiny platinum of the same geometry and also having improved resistance to physical stress when compared to platinum black having the same surface area. The process of electroplating the surface coating of platinum gray comprising plating at a moderate rate, i.e., at a rate that is faster than the rate necessary to produce shiny platinum and that is less than the rate necessary to produce platinum black. |
| FILED | Friday, August 23, 2002 |
| APPL NO | 10/226976 |
| ART UNIT | 1775 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/264 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974568 | Piomelli |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniele Piomelli (Irvine, California) |
| ABSTRACT | The invention discloses the existence of cannabinoid receptors in the airways, which are functionally linked to inhibition of cough. Locally acting cannabinoid agents can be administered to the airways of a subject to ameliorate cough, without causing the psychoactive effects characteristic of systemically administered cannabinoids. In addition, locally or systemically administered cannabinoid inactivation inhibitors can also be used to ameliorate cough. The present invention also defines conditions under which cannabinoid agents can be administered to produce anti-tussive effects devoid of bronchial constriction. |
| FILED | Wednesday, May 23, 2001 |
| APPL NO | 09/864920 |
| ART UNIT | 1614 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974574 | Walker et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Bruce D. Walker (Milton, Massachusetts); Marcus Altfeld (Arlington, Massachusetts) |
| ABSTRACT | The invention features an immunogenic composition containing a frequently-recognized epitope of an HIV-1 accessory protein such as Vpr and methods of inducing an immune response using such an epitope. The epitope peptide contains the amino acid sequence ALIRILQQL of a functionally active domain or a structural domain of the accessory protein. |
| FILED | Friday, August 16, 2002 |
| APPL NO | 10/222463 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/192.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974580 | Bertozzi et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carolyn R. Bertozzi (Berkeley, California); Spencer J. Williams (Berkeley, California); Joseph D. Mougous (El Cerrito, California) |
| ABSTRACT | Novel mycobacterial sulfation pathway proteins and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting growth and/or virulence of a pathogenic mycobacterium, and methods of treating disease conditions associated with a pathogenic mycobacterium, particularly by administering an inhibitor of a mycobacterial sulfation pathway protein. The present invention further provides genetically modified mycobacteria having a defect in a sulfation pathway enzyme gene; and immunogenic compositions that include such genetically modified mycobacteria. |
| FILED | Tuesday, July 13, 2004 |
| APPL NO | 10/891383 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/248.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974664 | Khosla et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford University (Palo Alto, California) |
| INVENTOR(S) | Chaitan Khosla (Palo Alto, California); Art Salomon (San Diego, California) |
| ABSTRACT | Screening methods and methods of treatment taking advantage of the mode of action of apoptolidin and its analogs are described. |
| FILED | Wednesday, July 25, 2001 |
| APPL NO | 09/916233 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974666 | Lockhart et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Appymetric, Inc. (Santa Clara, California) |
| INVENTOR(S) | David J. Lockhart (Mountain View, California); Mark S. Chee (Palo Alto, California); Dirk Vetter (Weimar-Gabendorf, Germany); Martin Digglemann (Niederdorf, Switzerland) |
| ABSTRACT | Methods for discriminating between fully complementary hybrids and those that differ by one or more base pairs and libraries of unimolecular, double-stranded oligonucleotides on a solid support. In one embodiment, the present invention provides methods of using nuclease treatment to improve the quality of hybridization signals on high density oligonucleotide arrays. In another embodiment, the present invention provides methods of using ligation reactions to improve the quality of hybridization signals on high density oligonucleotide arrays. In yet another embodiment, the present invention provides libraries of unimolecular or intermolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries. |
| FILED | Wednesday, October 18, 1995 |
| APPL NO | 08/533582 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974669 | Mirkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nanosphere, Inc. (Northbrook, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); So-Jung Park (Evanston, Illinois); Jwa-Min Nam (Evanston, Illinois) |
| ABSTRACT | The present invention relates to a screening methods, compositions, and kits for detecting for the presence or absence of one or more target analytes, e.g. proteins such as antibodies, in a sample. In particular, the present invention relates to a method that utilizes reporter oligonucleotides as biochemical barcodes for detecting multiple protein structures or other target analytes in one solution. |
| FILED | Wednesday, March 27, 2002 |
| APPL NO | 10/108211 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974671 | Montminy et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Marc R. Montminy (San Diego, California); Bruce M. Spiegelman (Waban, Massachusetts); Stephan Herzig (Del Mar, California) |
| ABSTRACT | In accordance with the present invention, it has been discovered that CREB regulates hepatic gluconeogenesis via the co-activator, PGC-1. PGC-1 potentiated glucocorticoid induction of the gene for PEPCK, the rate limiting enzyme in gluconeogenesis, via the glucocorticoid response unit in the promoter, indicating that activation of PGC-1 by CREB in liver contributes to the pathogenesis of diabetes mellitus. In accordance with the above discoveries, the present invention provides a method of identifying a compound that modulates gluconeogenesis. The invention method comprises contacting CREB and a nucleic acid comprising a PGC-1 promoter with a test compound, and determining if the test compound modulates binding between CREB and the PGC-1 promoter. |
| FILED | Wednesday, September 11, 2002 |
| APPL NO | 10/244045 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974697 | Comer et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Stratech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Allen Comer (Madison, Wisconsin); Lynn Allen-Hoffmann (Madison, Wisconsin); Michael Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to in vitro cultured skin substitutes, and in particular to in vitro cultured skin substitutes that have improved barrier function. In some embodiments, improved barrier function is a result of improved culture conditions, while in other embodiments, improved barrier function results from genetic modification of keratinocytes. Improved culture conditions to improve barrier function include organotypic culture in the presence of linoleic acid and/or linoleic acid at about 75% humidity. Suitable genetic modifications for improving barrier function includes transfection with a DNA construct capable of expressing GKLF. |
| FILED | Friday, March 01, 2002 |
| APPL NO | 10/087346 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974698 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Jeffery L. Miller (Potomac, Maryland); Urszula Wojda (Warsaw, Poland); Paul K. Goldsmith (Rockville, Maryland) |
| ABSTRACT | Methods for delivering a biologically active molecule into a cell by linking a molecule to the cell surface, wherein the molecule can act as a surface receptor, then complexing the biologically active molecule with a ligand for the surface receptor, and finally contacting the biologically active molecule-ligand complex with the cell surface are disclosed. Delivery of any biologically active molecule, e.g. proteins, enzymes, nucleic acids, hormones, nucleic acids, and oligonucleotides, is contemplated. The use of biotin or biotinylated antibodies as the surface receptor is disclosed. The use of PEI and PEI-avidin conjugates complexed with oligonucleotides for delivery into a directly or indirectly biotinylated cell surface, along with the PEI-avidin-nucleic acid compositions, are disclosed. Primary and cultured cells with a covalently linked surface receptor molecule, such as biotin, on their surfaces are also disclosed. |
| FILED | Friday, January 14, 2000 |
| APPL NO | 09/483434 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974700 | Levine |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin Levine (Norman, Oklahoma) |
| ABSTRACT | A kit and method of predicting a refractory response in a subject diagnosed as having periodontal disease by measuring serum concentrations of actinomyces antibodies, streptococcal antibodies and lysine decarboxylase antibodies and using the measurement along with other subject information in a set of derived equations. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/456664 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/975 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974801 | Honda et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Dartmounth College (Hanover, New Hampshire) |
| INVENTOR(S) | Tadashi Honda (Hanover, New Hampshire); Yukiko Honda (Hanover, New Hampshire); Gordon W. Gribble (Lebanon, New Hampshire); Michael B. Sporn (Tunbridge, Vermont); Nanjoo Suh (White River Junction, Vermont) |
| ABSTRACT | New triterpenoid derivatives with various substituents at the C-17 position of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) were synthesized. Among them, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile (CNDDO), 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl) imidazole, 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl)-2-methylimidazole, 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl)-4-methylimidazole show extremely high inhibitory activity (IC50=0.01-1 pM level) against production of nitric oxide induced by interferon-γ in mouse macrophages. These compounds can be used in the prevention or treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, rheumatoid arthritis, and other inflammatory diseases. All the new triterpenoid derivatives are more potent than previously known CDDO. |
| FILED | Monday, May 12, 2003 |
| APPL NO | 10/435925 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974863 | Kwon |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Indiana University Research and technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Byoung S. Kwon (Carmel, Indiana) |
| ABSTRACT | The present invention includes the receptor protein 4-1BB and the cDNA gene encoding for receptor protein 4-1BB. The nucleotide sequence of the isolated cDNA is disclosed herein along with the deduced amino acid sequence. The 4-1BB protein and fragments and derivatives can be used: 1) as a probe to isolate ligands to receptor protein 4-1BB, 2) to stimulate proliferation of B-cell's expressing 4-1BB, or 3) to block 4-1BB ligand binding. A monoclonal antibody against 4-1BB was developed which specifically recognizes an epitope on the extracellular domain of receptor protein 4-1BB. The monoclonal antibody can be used enhance T-cell proliferation and activation by treating T-cells that have expressed receptor protein 4-1BB with the monoclonal antibody. The effectiveness of the treatment was enhanced when conducted in the presence of protein tyrosinase kinase. A fusion protein for detecting cell membrane ligands to receptor protein 4-1BB was developed. It comprises the extracellular portion of the receptor protein 4-1BB and a detection protein bound to the portion of the receptor protein 4-1BB. |
| FILED | Monday, February 04, 2002 |
| APPL NO | 10/067122 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974871 | Rotenberg |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Susan A. Rotenberg (Bayside, New York) |
| ABSTRACT | A composition for protecting human skin from harmful effects of the sun, the composition comprising a topically effective amount of: (a) a first chemical compound that absorbs ultraviolet light sufficiently to reduce significantly the damage to human skin from harmful effects of ultraviolet light; and (b) a second chemical compound having the formula: (Q-T)u+X−v wherein: Q represents 4-E-2-R3-1-quinolinium; E represents NR1R2, COO R1, OR1, I, Br, Cl, F, or NO3 N represents a nitrogen atom; R1 and R2 independently represent hydrogen or lower alkyl; R3 represents E, hydrogen or lower alkyl; T represents hydrogen or a chain comprising m atoms, the atoms in the chain being t carbon atoms and 0 to approximately 0.5t heteroatoms; the minimum value of m is 6; the maximum value of m is 22; X represents an anion; and u and v represent 1, 2, or 3 with the proviso that u=v. |
| FILED | Friday, June 25, 2004 |
| APPL NO | 10/876982 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/167 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974884 | Raines et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Laura L. Kiessling (Madison, Wisconsin); Bradley L. Nilsson (Madison, Wisconsin); Yi He (Madison, Wisconsin); Matthew B. Soellner (Madison, Wisconsin); Ronald J. Hinklin (Longmont, Colorado) |
| ABSTRACT | The present invention provides improved methods for synthesis of phosphinothiol reagents, as well as novel protected reagents, for use in formation of amide bonds, and particularly for peptide ligation. The invention provides phosphine-borane complexes useful as reagents in the formation of amide bonds, particularly for the formation of an amide bond between any two of an amino acid, a peptide, or a protein. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/456988 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975894 | Wehrli et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Felix W. Wehrli (Bala Cynwyd, Pennsylvania); Punam K. Saha (Philadelphia, Pennsylvania); Bryon Roos Gomberg (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention provides method, system and device for determining trabecular bone structure and strength by digital topological analysis, and offers, for the first time, a demonstration of superior associations between vertebral deformity and a number of architectural indices measured in the distal radius, thus permitting reliable and noninvasive detection and determination of the pathogenesis of osteoporosis. A preferred embodiment provides imaging in three dimension of a region of trabecular bone, after which the 3D image is converted into a skeletonized surface representation. Digital topological analysis is applied to the converted image, and each image voxel is identified and classified as a curve, a surface, or a junction; and then associated with microarchitectural indices of trabecular bone to quantitatively characterize the trabecular bone network. The invention is applicable in vivo, particularly on human subjects, or ex vivo. |
| FILED | Thursday, April 11, 2002 |
| APPL NO | 10/121470 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975900 | Rudy et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Yoram Rudy (Shaker Heights, Ohio); Charulatha Ramanathan (Richmond Heights, Ohio); Raja Ghanem (Cleveland Heights, Ohio); Ping Jia (University Heights, Ohio) |
| ABSTRACT | Methods and systems for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the object using the first imaging device, obtaining at least one second 2D image of the object using the second imaging device, determining a contour of the object in the first 2D image and the second 2D image, and, based on the at least two contours, the first projection matrix, and the second projection matrix, reconstructing 3D data associated with the surface of the object. In one embodiment, the object can be a heart. |
| FILED | Thursday, December 12, 2002 |
| APPL NO | 10/317953 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 6/523 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975943 | Gibbs et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Seqwright, Inc. (Houston, Texas) |
| INVENTOR(S) | Richard Gibbs (Houston, Texas); Allan Bradley (Cambridge, United Kingdom); Wei-Wen Cai (Houston, Texas) |
| ABSTRACT | A simplified strategy for sequencing large genomes has been developed. Clone-Array Pooled Shotgun Sequencing (CAPSS) is based upon pooling rows and columns of arrayed genomic clones, for shotgun library construction. Random sequences are accumulated and the data are assembled by sequential comparison of rows and columns, to resolve the sequence of clones at points of intersection. Compared to either a clone-by-clone approach or whole genome shotgun sequencing, CAPSS requires relatively few library constructions and only minimal computational power for a complete genome assembly. The strategy is suitable for sequencing large genomes for which there are no sequence-ready maps, but for which relatively high resolution STS maps and highly redundant BAC libraries are available. It is immediately applicable to the sequencing of mouse, rat, zebra fish and other important genomes, and can be managed in a cooperative fashion to take advantage of the distributed international DNA sequencing capacity. |
| FILED | Monday, September 24, 2001 |
| APPL NO | 09/969111 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 06973883 | Annamalai et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Kalyan Annamalai (College Station, Texas); John M. Sweeten (Amarillo, Texas) |
| ABSTRACT | The present invention pertains to the use of feedlot biomass as reburn fuel matter to reduce NOx emissions. According to one embodiment of the invention, feedlot biomass is used as the reburn fuel to reduce NOx. The invention also includes burners and boiler in which feedlot biomass serves a reburn fuel. |
| FILED | Friday, March 22, 2002 |
| APPL NO | 10/104288 |
| ART UNIT | 3749 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Furnaces 110/345 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06973921 | Shafer et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Scott F. Shafer (Morton, Illinois); Lifeng Wang (Normal, Illinois) |
| ABSTRACT | A fuel pumping system that includes a pump drive is provided. A first pumping element is operatively connected to the pump drive and is operable to generate a first flow of pressurized fuel. A second pumping element is operatively connected to the pump drive and is operable to generate a second flow of pressurized fuel. A first solenoid is operatively connected to the first pumping element and is operable to vary at least one of a fuel pressure and a fuel flow rate of the first flow of pressurized fuel. A second solenoid is operatively connected to the second pumping element and is operable to vary at least one of a fuel pressure and a fuel flow rate of the second flow of pressurized fuel. |
| FILED | Friday, December 12, 2003 |
| APPL NO | 10/733444 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/495 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06973993 | West et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Phillip B. West (Idaho Falls, Idaho); Daryl Haefner (Idaho Falls, Idaho) |
| ABSTRACT | Methods and apparatus for attenuating waves in a bore hole, and seismic surveying systems incorporating the same. In one embodiment, an attenuating device includes a soft compliant bladder coupled to a pressurized gas source. A pressure regulating system reduces the pressure of the gas from the gas source prior to entering the bladder and operates in conjunction with the hydrostatic pressure of the fluid in a bore hole to maintain the pressure of the bladder at a specified pressure relative to the surrounding bore hole pressure. Once the hydrostatic pressure of the bore hole fluid exceeds that of the gas source, bore hole fluid may be admitted into a vessel of the gas source to further compress and displace the gas contained therein. In another embodiment, a water-reactive material may be used to provide gas to the bladder wherein the amount of gas generated by the water-reactive material may depend on the hydrostatic pressure of the bore hole fluid. |
| FILED | Tuesday, June 29, 2004 |
| APPL NO | 10/881529 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Acoustics 181/102 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974070 | Goretta et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Kenneth C. Goretta (Downers Grove, Illinois); Jules L. Routbort (Hinsdale, Illinois); Felipe Gutierrez-Mora (Woodridge, Illinois) |
| ABSTRACT | A method for utilizing superplastic deformation with or without a novel joint compound that leads to the joining of advanced ceramic materials, intermetallics, and cermets. A joint formed by this approach is as strong as or stronger than the materials joined. The method does not require elaborate surface preparation or application techniques. |
| FILED | Tuesday, August 07, 2001 |
| APPL NO | 09/924571 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Metal fusion bonding 228/248.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974178 | Ortega et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jason M. Ortega (Pacifica, California); Kambiz Salari (Livermore, California) |
| ABSTRACT | An apparatus for reducing the aerodynamic drag of a wheeled vehicle in a flowstream, the vehicle having a vehicle body and a wheel assembly supporting the vehicle body. The apparatus includes a baffle assembly adapted to be positioned upstream of the wheel assembly for deflecting airflow away from the wheel assembly so as to reduce the incident pressure on the wheel assembly. |
| FILED | Tuesday, February 24, 2004 |
| APPL NO | 10/786531 |
| ART UNIT | 3612 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Land vehicles: Bodies and tops 296/180.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974496 | Wegeng et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Robert S. Wegeng (Richland, Washington); Scot D. Rassat (Benton City, Washington); Victoria S. Stenkamp (Richland, Washington); Ward E. TeGrotenhuis (Kennewick, Washington); Dean W. Matson (Kennewick, Washington); M. Kevin Drost (Corvallis, Oregon); Vilayanur V. Viswanathan (Richland, Washington) |
| ABSTRACT | The present invention provides compact adsorption systems that are capable of rapid temperature swings and rapid cycling. Novel methods of thermal swing adsorption and thermally-enhanced pressure swing adsorption are also described. In some aspects of the invention, a gas is passed through the adsorbent thus allowing heat exchangers to be very close to all portions of the adsorbent and utilize less space. In another aspect, the adsorption media is selectively heated, thus reducing energy costs. Methods and systems for gas adsorption/desorption having improved energy efficiency with capability of short cycle times are also described. Advantages of the invention include the ability to use (typically) 30-100 times less adsorbent compared to conventional systems. |
| FILED | Monday, June 30, 2003 |
| APPL NO | 10/609501 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas separation: Apparatus 096/126 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974624 | Mulligan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Ceramics Research, Inc. (Tuscon, Arizona) |
| INVENTOR(S) | Anthony C. Mulligan (Tucson, Arizona); Mark J. Rigali (Tucson, Arizona); Manish P. Sutaria (Malden, Massachusetts); Dragan Popovich (Redmond, Washington); Joseph P. Halloran (Tucson, Arizona); Michael L. Fulcher (Tucson, Arizona); Randy C. Cook (Tucson, Arizona) |
| ABSTRACT | Fibrous monolith composites having architectures that provide increased flaw insensitivity, improved hardness, wear resistance and damage tolerance and methods of manufacture thereof are provided for use in dynamic environments to mitigate impact damage and increase wear resistance. |
| FILED | Wednesday, December 04, 2002 |
| APPL NO | 10/310594 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/304.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974704 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Intrinsic Bioprobes, Inc. (Tempe, Arizona) |
| INVENTOR(S) | Randall W. Nelson (Ahwahtukee, Arizona); Peter Williams (Phoenix, Arizona); Jennifer Reeve Krone (Phoenix, Arizona) |
| ABSTRACT | Rapid mass spectrometric immunoassay methods for detecting and/or quantifying antibody and antigen analytes utilizing affinity capture to isolate the analytes and internal reference species (for quantification) followed by mass spectrometric analysis of the isolated analyte/internal reference species. Quantification is obtained by normalizing and calibrating obtained mass spectrum against the mass spectrum obtained for an antibody/antigen of known concentration. |
| FILED | Wednesday, March 14, 2001 |
| APPL NO | 09/808275 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974893 | Shanklin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | John Shanklin (Shoreham, New York); Edward J. Whittle (Greenport, New York) |
| ABSTRACT | The present invention relates to oleate hydroxylase genes, proteins, and methods of their use. The present invention also relates to methods of using the oleate hydroxylase genes and proteins, including in their expression in transgenic organisms and in the production of hydroxylated fatty acids. |
| FILED | Friday, June 28, 2002 |
| APPL NO | 10/185578 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/281 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974950 | Leung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ka-Ngo Leung (Hercules, California); Jani Reijonen (Oakland, California) |
| ABSTRACT | The positive and negative ion beam merging system extracts positive and negative ions of the same species and of the same energy from two separate ion sources. The positive and negative ions from both sources pass through a bending magnetic field region between the pole faces of an electromagnet. Since the positive and negative ions come from mirror image positions on opposite sides of a beam axis, and the positive and negative ions are identical, the trajectories will be symmetrical and the positive and negative ion beams will merge into a single neutral beam as they leave the pole face of the electromagnet. The ion sources are preferably multicusp plasma ion sources. The ion sources may include a multi-aperture extraction system for increasing ion current from the sources. |
| FILED | Friday, August 30, 2002 |
| APPL NO | 10/232503 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Radiant energy 250/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975072 | Leung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ka-Ngo Leung (Hercules, California); Qing Ji (Albany, California); Stephen Wilde (Pleasant Hill, California) |
| ABSTRACT | A radio frequency (RF) driven plasma ion source has an external RF antenna, i.e. the RF antenna is positioned outside the plasma generating chamber rather than inside. The RF antenna is typically formed of a small diameter metal tube coated with an insulator. An external RF antenna assembly is used to mount the external RF antenna to the ion source. The RF antenna tubing is wound around the external RF antenna assembly to form a coil. The external RF antenna assembly is formed of a material, e.g. quartz, which is essentially transparent to the RF waves. The external RF antenna assembly is attached to and forms a part of the plasma source chamber so that the RF waves emitted by the RF antenna enter into the inside of the plasma chamber and ionize a gas contained therein. The plasma ion source is typically a multi-cusp ion source. |
| FILED | Thursday, May 22, 2003 |
| APPL NO | 10/443575 |
| ART UNIT | 2821 — Optics |
| CURRENT CPC | Electric lamp and discharge devices: Systems 315/111.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975229 | Carrender |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute K1-53 (Richland, Washington) |
| INVENTOR(S) | Curt Carrender (Morgan Hill, California) |
| ABSTRACT | A system and method for acquisition management of subject position information that utilizes radio frequency identification (RF ID) to store position information in position tags. Tag programmers receive position information from external positioning systems, such as the Global Positioning System (GPS), from manual inputs, such as keypads, or other tag programmers. The tag programmers program each position tag with the received position information. Both the tag programmers and the position tags can be portable or fixed. Implementations include portable tag programmers and fixed position tags for subject position guidance, and portable tag programmers for collection sample labeling. Other implementations include fixed tag programmers and portable position tags for subject route recordation. Position tags can contain other associated information such as destination address of an affixed subject for subject routing. |
| FILED | Friday, August 09, 2002 |
| APPL NO | 10/215710 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Communications: Electrical 340/572.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975245 | Slater et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | John M. Slater (Idaho Falls, Idaho); John M. Svoboda (Idaho Falls, Idaho) |
| ABSTRACT | A data acquisition and telemetry based control system for use in facilitating substantially real time management of an agricultural irrigation system. The soil moisture sensor includes a reader and a plurality of probes. The probes each include an electronic circuit having a moisture sensing capacitor in operative communication with the soil whose moisture is to be measured. Each probe also includes a receive/transmit antenna and the reader includes a transmit/receive antenna, so that as the reader passes near the probe, the reader transmits a digital excitation signal to the electronic circuit of the biodegradable probe via an inductive couple formed between the transmit/receive antenna of the reader and the receive/transmit coil of the probe. The electronic circuit uses an energy component of the excitation signal to generate a digital data signal which indicates the moisture content of the soil adjacent to the moisture sensing capacitor. The probe sends the data signal to the reader which then uses the data signal to develop a corresponding set of watering instructions which are then transmitted to a control module in communication with the irrigation system. The control module sends corresponding control signals to nozzles of the irrigation system causing the irrigation system to disperse water in a manner consistent with the moisture content data transmitted by the probes to the reader. Because the irrigation system moves continuously through the field to be irrigated, the moisture content data acquisition and resultant water dispersal by the irrigation system occur substantially in real time. |
| FILED | Monday, September 18, 2000 |
| APPL NO | 09/665229 |
| ART UNIT | 2635 — Optical Communications |
| CURRENT CPC | Communications: Electrical 340/870.160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06975402 | Bisson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia National Laboratories (Livermore, California) |
| INVENTOR(S) | Scott E. Bisson (Livermore, California); Thomas J. Kulp (Livermore, California); Karla M. Armstrong (Livermore, California) |
| ABSTRACT | The present invention provides a photoacoustic spectrometer that is field portable and capable of speciating complex organic molecules in the gas phase. The spectrometer has a tunable light source that has the ability to resolve the fine structure of these molecules over a large wavelength range. The inventive light source includes an optical parametric oscillator (OPO) having combined fine and coarse tuning. By pumping the OPO with the output from a doped-fiber optical amplifier pumped by a diode seed laser, the inventive spectrometer is able to speciate mixtures having parts per billion of organic compounds, with a light source that has a high efficiency and small size, allowing for portability. In an alternative embodiment, the spectrometer is scanned by controlling the laser wavelength, thus resulting in an even more compact and efficient design. |
| FILED | Tuesday, November 19, 2002 |
| APPL NO | 10/300421 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/432 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 06974508 | Gabb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Timothy P. Gabb (Independence, Ohio); John Gayda (Avon Lake, Ohio); Ignacy Telesman (Hudson, Ohio); Pete T. Kantzos (Canton, Ohio) |
| ABSTRACT | A low solvus, high refractory alloy having unusually versatile processing mechanical property capabilities for advanced disks and rotors in gas turbine engines. The nickel base superalloy has a composition consisting essentially of, in weight percent, 3.0–4.0 Al, 0.02–0.04 B, 0.02–0.05 C, 12.0–14.0 Cr, 19.0–22.0 Co, 2.0–3.5 Mo, greater than 1.0 to 2.1 Nb, 1.3 to 2.1 Ta, 3.0–4.0 Ti, 4.1 to 5.0 W, 0.03–0.06 Zr, and balance essentially Ni aid incidental impurities. The superalloy combines ease of processing with high temperature capabilities to be suitable for use in various turbine engine disk, impeller, and shaft applications. The Co and Cr levels of the superalloy can provide low solvus temperature for high processing versatility. The W, Mo, Ta, and Nb refractory element levels of the superalloy can provide sustained strength, creep, and dwell crack growth resistance at high temperatures. |
| FILED | Tuesday, October 29, 2002 |
| APPL NO | 10/283220 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Metal treatment 148/428 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974678 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Mississippi State University (Mississippi State, Mississippi) |
| INVENTOR(S) | Wilbur W. Wilson (Starkville, Mississippi); Charles S. Henry (Fort Collins, Colorado); Carlos D. Garcia (Cordoba, Argentina) |
| ABSTRACT | A micro-fluidic device having a cavity containing a solid support (e.g., a plurality of particles) and a biomolecule immobilized on a surface of the solid support is provided. The micro-fluidic device can be used to monitor interactions between a biomolecule in a sample and the biomolecule immobilized on the solid support. For example, the micro-fluidic device can be used to monitor protein self-interactions wherein the protein in the sample is the same protein as that immobilized on the surface of the solid support. A method of making the micro-fluidic device is also described. The micro-fluidic device can be used for chromatographic applications where sample consumption is crucial. |
| FILED | Tuesday, October 08, 2002 |
| APPL NO | 10/265715 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974855 | Meador |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Michael A. Meador (Strongsville, Ohio) |
| ABSTRACT | The novel polyimides of this invention are derived from Diels-Alder cyclopolymerization of photochemically generated bisdienes with dienophiles, such as bismaleimides, trismaleimides and mixtures thereof with maleimide end-caps. Irradiation of one or more diketones produces two distinct hydroxy o-quinodimethane (photoenol) intermediates. These intermediates are trapped via Diels-Alder cycloaddition with appropriate dienophiles, e.g., bismaleimide and/or trismaleimides to give the corresponding polyimides in quantitative yields. When bismaleimides, trismaleimides or mixtures thereof with maleimide end-caps are used as the dienophile, the resulting polyimides have glass transition temperatures (Tg) as high as 300° C. Polyimide films can be prepared by ultraviolet irradiation of high solids content varnishes of the monomers in a small amount of solvent, e.g., cyclohexanone, dimethyl formamide, N-methylpyrollidone and the like. These novel polyimides are characterized as having high glass transition temperatures, good mechanical properties and improved processing in the manufacture of adhesives, electronic materials and films. |
| FILED | Tuesday, July 08, 2003 |
| APPL NO | 10/617447 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 528/228 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06976013 | Mah |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert W. Mah (Cupertino, California) |
| ABSTRACT | System and method for performing one or more relevant measurements at a target site in an animal body, using a probe. One or more of a group of selected internal measurements is performed at the target site, is optionally combined with one or more selected external measurements, and is optionally combined with one or more selected heuristic information items, in order to reduce to a relatively small number the probable medical conditions associated with the target site. One or more of the internal measurements is optionally used to navigate the probe to the target site. Neural net information processing is performed to provide a reduced set of probable medical conditions associated with the target site. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/874003 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 06974669 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Nanosphere, Inc. (Northbrook, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); So-Jung Park (Evanston, Illinois); Jwa-Min Nam (Evanston, Illinois) |
| ABSTRACT | The present invention relates to a screening methods, compositions, and kits for detecting for the presence or absence of one or more target analytes, e.g. proteins such as antibodies, in a sample. In particular, the present invention relates to a method that utilizes reporter oligonucleotides as biochemical barcodes for detecting multiple protein structures or other target analytes in one solution. |
| FILED | Wednesday, March 27, 2002 |
| APPL NO | 10/108211 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974706 | Melker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Richard J. Melker (Gainesville, Florida); Donn Michael Dennis (Gainesville, Florida) |
| ABSTRACT | A method for detecting compounds of interest in bodily fluids, including exhaled breath and blood. The present invention uses biosensors that mimic naturally occurring cellular mechanisms, including RNA oligonucleotide chains or “aptamers,” in combination with molecular beacons or nanotechnology to provide an effective and efficient method for diagnosing a condition and/or disease within a patient. The subject invention also provides a method for screening those analytes/biomarkers likely to be present in exhaled breath. |
| FILED | Thursday, January 16, 2003 |
| APPL NO | 10/345532 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/518 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06976150 | Uht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Governors for Higher Education, State of Rhode Island and Providence Plantations (Providence, Rhode Island) |
| INVENTOR(S) | Augustus K. Uht (Cumberland, Rhode Island); David Morano (Malden, Massachusetts); David Kaeli (Medway, Massachusetts) |
| ABSTRACT | A scalable processing system includes a memory device having a plurality of executable program instructions, wherein each of the executable program instructions includes a timetag data field indicative of the nominal sequential order of the associated executable program instructions. The system also includes a plurality of processing elements, which are configured and arranged to recieve executable program instructions from the memory device, wherein each of the processing elements executes executable instructions having the highest priority as indicated by the state of the timetag data field. |
| FILED | Friday, April 06, 2001 |
| APPL NO | 09/828600 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 06974356 | Hobson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Nekton Research LLC (Durham, North Carolina) |
| INVENTOR(S) | Brett W. Hobson (Carmel, California); Mathieu Kemp (Durham, North Carolina); Ryan Moody (Raleigh, North Carolina); Charles A. Pell (Durham, North Carolina); Frederick Vosburgh (Durham, North Carolina) |
| ABSTRACT | Devices for navigating in a fluid medium having a solid boundary include a vehicle body and a fin attached to the vehicle body. The fin is configured to oscillate relative to the body such that interaction between the fin and the fluid medium produces propulsive forces that propel the vehicle body in a desired direction in the fluid medium. The fin is also configured to rotate relative to the body along a transverse axis such that engagement between the fin and the solid boundary propels the vehicle body in a desired direction on the solid boundary. |
| FILED | Tuesday, May 18, 2004 |
| APPL NO | 10/848330 |
| ART UNIT | 3617 — Optics |
| CURRENT CPC | Marine propulsion 440/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 06974697 | Comer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Stratech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Allen Comer (Madison, Wisconsin); Lynn Allen-Hoffmann (Madison, Wisconsin); Michael Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to in vitro cultured skin substitutes, and in particular to in vitro cultured skin substitutes that have improved barrier function. In some embodiments, improved barrier function is a result of improved culture conditions, while in other embodiments, improved barrier function results from genetic modification of keratinocytes. Improved culture conditions to improve barrier function include organotypic culture in the presence of linoleic acid and/or linoleic acid at about 75% humidity. Suitable genetic modifications for improving barrier function includes transfection with a DNA construct capable of expressing GKLF. |
| FILED | Friday, March 01, 2002 |
| APPL NO | 10/087346 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 06975699 | Kresse |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | InVision Technologies, Inc. (Newark, California) |
| INVENTOR(S) | David E. Kresse (Walnut Creek, California) |
| ABSTRACT | In one embodiment, the invention provides a method for mounting a plurality of detector modules to a rotatable gantry structure for an x-ray detection machine. The method comprises mounting the plurality of detector modules end-to-end to define a stair-step configuration in an x-ray detection zone of the rotatable gantry structure. |
| FILED | Wednesday, February 19, 2003 |
| APPL NO | 10/369712 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US D512804 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Wilson (Fairfax Station, Virginia); F. Andrew Better (Herndon, Virginia); Edgar T. Bellinger, Jr. (Bethesda, Maryland); Duane C. Hajos (Rockville, Maryland) |
| ABSTRACT | |
| FILED | Friday, July 30, 2004 |
| APPL NO | 29/210344 |
| ART UNIT | 2912 — Design |
| CURRENT CPC | Miscellaneous D99/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US RE38918 | Svensson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Lars G. Svensson (Lund, Sweden); William C. Athas (Torrance, California); Jeffrey G. Koller (Torrance, California) |
| ABSTRACT | A system and method for efficiently charging and discharging a capacitive load from a single voltage source. The system includes a brat switch for selectively connecting the voltage source to the load and a second switch for selectively providing a short across the load as may he common in the art. A particularly novel aspect of the invention resides in the provision of plural capacitive elements and a switching mechanism for selectively connecting each of the capacitive elements to the load whereby the load is gradually charged or discharged. In the illustrative embodiment, the switching mechanism includes a set of switches for selectively connecting each of the capacitive elements to the capacitive load and a switch control mechanism for selectively activating the switches. |
| FILED | Wednesday, January 10, 2001 |
| APPL NO | 09/758631 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electric power conversion systems 363/60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 13, 2005.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2005/fedinvent-patents-20051213.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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