FedInvent™ Patents

Patent Details for Tuesday, April 18, 2006 

This page was updated on Sunday, March 26, 2023 at 08:02 PM GMT

Department of Health and Human Services (HHS) 

US 07029652 DeNardo et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Merck Patent GmbH (Darmstadt, Germany)
INVENTOR(S) Sally J. DeNardo (El Macerco, California);  Patricia A. Burke (Sacramento, California);  Gerald L. DeNardo (El Macerco, California);  Simon Goodman (Darmstadt, Germany);  Kerstin Matzku, legal representative (Zwingenberg, Germany)
ABSTRACT A method of treating tumors, such as prostate tumors, breast tumors, non-Hodgkin's lymphoma, and the like, includes the sequential steps of administering to the patient at least one dose of an antiangiogenic cyclo-arginine-glycine-aspartic acid-containing pentapeptide (cRGD pentapeptide); administering to the patient an anti-tumor effective amount of a radioimmunotherapeutic agent (RIT); and then administering to the patient at least one additional dose of cRGD pentapeptide. The cRGD pentapeptide is preferably cyclo-(Arg-Gly-Asp-D-Phe-[N-Me]-Val), and the RIT is preferably a radionuclide-labeled chelating agent-ligand complex in which chelating agent is chemically bonded to a tumor-targeting molecule, such as a monoclonal antibody.
FILED Wednesday, July 31, 2002
APPL NO 10/208931
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.490
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029673 Lambeth et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) J. David Lambeth (Decatur, Georgia);  Guangjie Cheng (Lilburn, Georgia)
ABSTRACT The present invention relates to nucleotides encoding for the production of novel regulatory proteins for Nox enzymes involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these nucleotides, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these nucleotides and proteins, and methods to determine the activity of drugs to affect the biological activity of the regulatory proteins of the present invention.
FILED Wednesday, July 16, 2003
APPL NO 10/621113
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/94.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029676 Brenner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Michael B. Brenner (Newton, Massachusetts);  Karyn L. Cepek (Brookline, Massachusetts)
ABSTRACT The present invention relates to methods and compositions for modulating the heterotypic adhesion between E-cadherin expressing cells and T lymphocytes. Monoclonal antibodies which specifically bind to E-cadherin and isolated peptides which mimic the binding function of E-cadherin also are provided. The antibodies and peptides are useful in screening assays to identify pharmaceutical lead compounds which are capable of modulating adhesion between T lymphocytes and E-cadherin expressing cells. Methods and pharmaceutical compositions for modifying the mucosal immune response of a subject also are provided.
FILED Friday, June 07, 2002
APPL NO 10/165049
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/154.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029688 Hubbell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jeffrey A. Hubbell (Zurich, Switzerland);  Natalie D. Winblade (Seattle, Washington);  Donald L. Elbert (St. Louis, Missouri)
ABSTRACT The invention discloses materials that adsorb readily to the surfaces of body tissues in situ and provide a steric barrier between such tissues, so that tissue adhesions, which typically form following surgical procedures, are minimized. These materials contain a polymer of hydrophilic molecules such as polyethylene glycol (PEG) bound to a polymer that spontaneously adsorbs to biological tissue such as phenylboronic acid (PBA). The PEG-PBA co-polymer can be formed in a variety of geometries. The materials can also be used to coat prosthetics and other implants.
FILED Friday, March 28, 2003
APPL NO 10/403344
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/422
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US 07029697 Segura et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tatiana Segura (Evanston, Illinois);  Lonnie D. Shea (Evanston, Illinois);  Angela Kaye Pannier (Glenview, Illinois);  Zain Bengali (Naperville, Illinois);  Jae-Hyung Jang (Skokie, Illinois);  Peter Chung (Montgomery, Alabama);  Brian C. Anderson (Libertyville, Illinois)
ABSTRACT A system and methods for controlled gene delivery comprising condensed nucleic acids complexed with polylinkers, wherein the complexes are covalently and/or non-covalently bound to the surface of a substrate capable of supporting cell adhesion. The gene delivery system achieves temporal and spatial control of nucleic acid delivery to a target cell or cells through control of complex density on the surface of the support substrate, and reversibility of the attachment of the polylinker to the support substrate. The system and method of the invention can be used to create spatial patterns of gene expression, and in tissue engineering, high throughput screening, and gene therapy applications.
FILED Thursday, July 15, 2004
APPL NO 10/893572
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/450
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US 07029700 Mathiowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Brown University Research Foundation (Providence, Rhode Island)
INVENTOR(S) Edith Mathiowitz (Brookline, Massachusetts);  Yong S. Jong (Providence, Rhode Island);  Jules S. Jacob (Taunton, Massachusetts)
ABSTRACT A process is provided for making dry, micronized particles of an agent, such as a drug. The method includes (a) dissolving a macromolecular material, preferably a polymer, in an effective amount of a solvent, to form a solution; (b) dissolving or dispersing the agent in the solution to form a mixture; (c) freezing the mixture; and (d) drying by vacuum the mixture to form solid particles of the agent dispersed in solid macromolecular material. The micronization in this process occurs directly in a macromolecular matrix and hardening of the particles of agent by solvent removal takes place by lyophilization of the bulk matrix, which stabilizes the drug particles during hardening and prevents coalesence, thereby resulting in smaller final drug particles. The method is particularly preferred for protein agents. The process can be used in conjunction with a standard microencapsulation technique, typically following separation of the agent from the macromolecular matrix. The process yields microparticles having a homogenous size distribution, preferably less than 2 μm, and more preferably less than 1 μm, in size. The microparticles have well defined, predictable properties, which is particularly critical in drug delivery applications.
FILED Friday, January 12, 2001
APPL NO 09/760046
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/489
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US 07029846 Rana et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Tariq M. Rana (Shrewsbury, Massachusetts);  Natarajan Tamilarasu (Highland Park, New Jersey)
ABSTRACT Site-specific modified proteins and method for producing site-specific modified proteins using amino acid analogs are disclosed. Methods for labeling proteins at a desired site in the presence of nucleophilic side chains, including lysine and cysteine side chains, are also disclosed. Methods for labeling the site-specific modified proteins are also disclosed.
FILED Thursday, October 04, 2001
APPL NO 09/972016
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07029859 Thompson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Baylor College of Medicine (Houston, Texas)
INVENTOR(S) Timothy C. Thompson (Houston, Texas)
ABSTRACT The present invention relates to methods for the diagnosis, evaluation and treatment of metastatic diseases using metastatic sequences, such as caveolin, to target metastatic cells. According to the methods of the present invention, certain cancers, including metastatic prostate cancer, may be treated by therapies which suppress expression of the caveolin gene. The present invention relates to biological technologies designed to block the activity of caveolin or the function of caveolae, including vector delivery of antisense caveolin sequences, the use of anti-caveolin antibodies, the use of promoters, and other approaches targeting the expression of caveolin.
FILED Monday, March 05, 2001
APPL NO 09/797969
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029863 Rothblat
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
INVENTOR(S) George H. Rothblat (Philadelphia, Pennsylvania)
ABSTRACT The present invention relates to a cell culture system to provide a tool for assessing the potential of a patient's serum for preventing the accumulation of cholesterol in arteries (i.e. serum efflux potential) that leads to atherosclerosis and to screen new drug compositions being developed to reduce the accumulation of cholesterol or enhance the clearance of cholesterol from the vessel wall. The present invention combines two individual assays, which are two different cholesterol assays: an assay measuring scavenger receptor class B type I (SR-BI)-mediated cholesterol efflux and an assay measuring ATP binding cassette protein 1 (ABCA1)-mediated cholesterol efflux, and uses them in parallel to test human and animal sera for their potential to stimulate efflux, as mediated by either of the two receptors described above.
FILED Wednesday, March 13, 2002
APPL NO 10/096705
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
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US 07029880 Weigel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Paul H. Weigel (Edmond, Oklahoma);  Kshama Kumari (Oklahoma City, Oklahoma);  Paul DeAngelis (Edmond, Oklahoma)
ABSTRACT The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Streptococcus equisimilis hyaluronate synthase (seHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan.
FILED Monday, May 02, 2005
APPL NO 11/120422
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/84
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US 07029890 Moore
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Siwa Biotech Corporation (Oklahoma City, Oklahoma)
INVENTOR(S) Kevin L. Moore (Oklahoma City, Oklahoma)
ABSTRACT Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.
FILED Monday, July 22, 2002
APPL NO 10/201525
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/193
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US 07029899 Rybak et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Susanna M. Rybak (Frederick, Maryland);  Dianne L. Newton (Rockville, Maryland)
ABSTRACT This invention provides RNase A superfamily polypeptides with modified amino terminal which can be used to selectively kill target Kaposi's sarcoma cells, neoplastic endothelial cells, and non-neoplastic endothelial cells. In certain embodiments of the invention, the amino terminal modification consists of an addition of 4 amino acid sequence consisting of the SLHV sequence at position −4 to −1 to the eosinophil derived neurotoxin protein. The amino terminal addition is capable of directing the claimed RNase A superfamily polypeptides to proliferating endothelial cells, such as Kaposi's sarcoma cells, and selectively killing these cells.
FILED Monday, November 01, 1999
APPL NO 09/807556
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/199
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US 07029911 Rine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jasper D. Rine (Moraga, California);  Victor L. Boyartchuk (Berkeley, California);  Matthew N. Ashby (Mill Valley, California)
ABSTRACT Two genes which encode polypeptides that mediate post-prenylation processing steps in CAAX polypeptides such as Ras are provided. The two genes (AFC1 and RCE1) encode polypeptides that mediate the removal of the AAX tripeptide from the CAAX polypeptide following prenylation. The genes and encoded polypeptides provide assays for testing compounds for an effect on post-prenylation processing steps. A heat shock assay for assessing Ras activity is also provided.
FILED Friday, October 02, 1998
APPL NO 09/165460
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 07029913 Thomson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) James A. Thomson (Madison, Wisconsin)
ABSTRACT A purified preparation of primate embryonic stem cells is disclosed. This preparation is characterized by the following cell surface markers: SSEA-1 (−); SSEA-4 (+); TRA-1-60 (+); TRA-1-81 (+); and alkaline phosphatase (+). In a particularly advantageous embodiment, the cells of the preparation are human embryonic stem cells, have normal karyotypes, and continue to proliferate in an undifferentiated state after continuous culture for eleven months. The embryonic stem cell lines also retain the ability, throughout the culture, to form trophoblast and to differentiate into all tissues derived from all three embryonic germ layers (endoderm, mesoderm and ectoderm). A method for isolating a primate embryonic stem cell line is also disclosed.
FILED Thursday, October 18, 2001
APPL NO 09/982637
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/363
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US 07029915 Yang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Lijun Yang (Gainesville, Florida)
ABSTRACT Highly purified hepatic stem cells are trans-differentiated into pancreatic endocrine hormone-producing cells by culturing them in vitro in a medium containing high levels of glucose. These trans-differentiated cells express insulin, glucagon, and pancreatic polypeptide, but not hepatocyte protein Hep-par. When stimulated with glucose, these cells synthesize and secrete insulin, a response enhanced by nicotinamide. Transplantation of these trans-differentiated cells into a hyperglycemic animal normalizes blood sugar levels in the animal.
FILED Monday, February 24, 2003
APPL NO 10/373124
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/377
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US 07030051 Davies
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Huw M. L. Davies (Clarence Center, New York)
ABSTRACT Disclosed is method for increasing the efficiency of a dirhodium catalyst. The method includes providing a dirhodium catalyst, providing an organic ester, and contacting the dirhodium catalyst and the organic ester under conditions effective to increase the efficiency of the dirhodium catalyst. The organic ester is selected such that it is not a substrate for catalysis by the dirhodium catalyst. Dirhodium catalyst compositions which include a dirhodium catalyst and an organic ester are also disclosed. In these compositions, the organic ester is not a substrate for catalysis by the dirhodium catalyst. The method and compositions can be used in a number of reactions, including insertion reactions (e.g., C—H insertions, Si—H insertions, O—H insertions, and N—H insertions) cyclopropanation reactions, annulations (e.g., [3+2] annulations and [3+4] annulations), and ω,ω-diarylalkanoate syntheses.
FILED Tuesday, August 27, 2002
APPL NO 10/229378
ART UNIT 1755 — Semiconductors/Memory
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/150
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US 07030080 Browning et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Biogen, Inc. (Cambridge, Massachusetts);  University of California (Oakland, California)
INVENTOR(S) Jeffrey Browning (Brookline, Massachusetts);  Carl F. Ware (Riverside, California)
ABSTRACT This invention relates to lymphotoxin-β, a lymphocyte membrane type protein. This protein is found on the surface of a number of cells, including phorbol ester (PMA) stimulated T cell hybridoma II-23.D7 cells. This invention also relates to complexes formed between lymphotoxin-β and other peptides such as lymphotoxin-α and to complexes comprising multiple subunits of lymphotoxin-β. These proteins and complexes are useful in holding LT-α formed within the cell on the cell surface where the LT-α/LT-β complex may act as an inflammation regulating agent, a tumor growth inhibiting agent, a T cell inhibiting agent, a T cell activating agent, an autoimmune disease regulating agent, or an HIV inhibiting agent. Furthermore, the antitumor activity of the LT-α/LT-β complex may be delivered to tumor cells by tumor infiltrating lymphocytes (TILs) transfected with the gene for LT-β.
FILED Wednesday, November 07, 2001
APPL NO 10/040281
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 07030097 Saltzman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) William Mark Saltzman (Ithaca, New York);  Dan Luo (Ithaca, New York);  Hong Shen (Ithaca, New York);  Kim Woodrow-Mumford (Tulare, California);  Nadya D. Belcheva (Ithaca, New York)
ABSTRACT One aspect of the present invention relates to a nucleic acid delivery system including a polymeric structure formed of a biocompatible polymer and a mixture comprising one or more nucleic acid molecules and a first co-dispersant, the mixture being contained within the polymeric structure, wherein the first co-dispersant is present in an amount effective to control diffusion of the one or more nucleic acid from the polymeric structure. Compositions including the nucleic acid delivery system and a pharmaceutically-acceptable carrier are disclosed. Methods of making the nucleic acid delivery system and their use in delivering nucleic acid into a patient and modifying gene expression in a target cell are also disclosed.
FILED Friday, July 14, 2000
APPL NO 09/616711
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07030100 Tao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Yuanxiang Tao (Baltimore, Maryland);  Roger A. Johns (Reistertown, Maryland)
ABSTRACT Several lines of evidence have shown a role for the nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling pathway in the development of spinal hyperalgesia. However, the roles of effectors for cGMP are not fully understood in the processing of pain in the spinal cord. cGMP-dependent protein kinase (PKG) Iα but not PKGIβ was localized in the neuronal bodies and processes, and was distributed primarily in the superficial laminae of the spinal cord. Intrathecal administration of an inhibitor of PKGIα, Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylamine, produces significant antinociception. Moreover, PKGIα protein expression was dramatically increased in the lumbar spinal cord after noxious stimulation. This upregulation of PKGIα expression was completely blocked not only by a neuronal NO synthase inhibitor, and a soluble guanylate cyclase inhibitor, but also by an N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801. Noxious stimulation not only initially activates but also later upregulates PKGIα expression in the superficial laminae via an NMDA-NO-cGMP signaling pathway, suggesting that PKGIα plays an important role in the central mechanism of inflammatory hyperalgesia in the spinal cord.
FILED Friday, June 28, 2002
APPL NO 10/183635
ART UNIT 1614 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/48
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US 07030146 Baynes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina);  Kansas University Medical Center (Kansas City, Kansas)
INVENTOR(S) John W. Baynes (Columbia, South Carolina);  Suzanne R. Thorpe (Columbia, South Carolina);  Thorsten P. Degenhardt (Durham, North Carolina);  Raja G. Khalifah (Overland Park, Kansas);  Billy G. Hudson (Lenexa, Kansas);  Nathan Alderson (West Columbia, South Carolina)
ABSTRACT A method for treating diabetic neuropathy is disclosed consisting of administering pyridoxamine or a salt thereof.
FILED Thursday, January 30, 2003
APPL NO 10/355442
ART UNIT 1614 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/351
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US 07030152 Ridker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Paul Ridker (Chestnut Hill, Massachusetts);  Charles H. Hennekens (Boca Raton, Florida)
ABSTRACT The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
FILED Tuesday, August 31, 1999
APPL NO 09/387028
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/423
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US 07030159 Serhan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Charles N. Serhan (Needham, Massachusetts);  Sean P. Colgan (North Reading, Massachusetts)
ABSTRACT Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. Various BPI inducing agents include icosapentanoic acid (EPA) analogs and docosahexaenoic acid (DHA) analogs.
FILED Wednesday, December 18, 2002
APPL NO 10/323867
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/560
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US 07030219 Pardoll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Drew M. Pardoll (Brookville, Maryland);  Haruo Tsuchiya (Baltimore, Maryland);  Kevin S. Gorski (Baltimore, Maryland);  Su-Yi Tseng (Baltimore, Maryland)
ABSTRACT A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.
FILED Wednesday, February 28, 2001
APPL NO 09/794210
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
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US 07030224 MacNicol
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Arkansas System (Little Rock, Arkansas)
INVENTOR(S) Angus M. MacNicol (Little Rock, Arkansas)
ABSTRACT The present invention provides genomic and cDNA encoding human cytoplasmic polyadenylation element binding protein, expression vectors comprising human cytoplasmic polyadenylation element binding protein cDNA and host cells that contain the expression vectors. Also provided are recombinant human cytoplasmic polyadenylation element binding protein and polypeptides derived thereof.
FILED Thursday, January 23, 2003
APPL NO 10/349852
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/358
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US 07030227 McKeon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Frank McKeon (Boston, Massachusetts);  Annie Yang (Boston, Massachusetts)
ABSTRACT This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.
FILED Thursday, October 15, 1998
APPL NO 09/529583
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.900
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US 07030231 Craik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Catalyst Biosciences, Inc. (South San Francisco, California)
INVENTOR(S) Charles S. Craik (San Francisco, California);  Toshihiko Takeuchi (San Francisco, California);  Marc Shuman (San Francisco, California)
ABSTRACT This invention provides a novel membrane-type serine protease (designated MT-SP1) elevated expression of which is associated with cancer. In one embodiment, this invention provides a method obtaining a prognosis or of detecting or staging a cancer in an organism. The method involves providing a biological sample from the organism and detecting the level of a membrane type serine protease 1 (MT-SP1) in the sample, where an elevated level of the membrane-type serine protease, as compared to the level of the protease in a biological sample from a normal healthy organism indicates the presence or stage of the cancer.
FILED Thursday, September 30, 1999
APPL NO 09/410362
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.100
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US 07030989 Yager et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Paul Yager (Seattle, Washington);  Elain S. Fu (Seattle, Washington)
ABSTRACT This invention provides methods, devices and device components for sensing, imaging and characterizing changes in the composition of a probe region. More particularly, the present invention provides methods and devices for detecting changes in the refractive index of a probe region positioned adjacent to a sensing surface, preferably a sensing surface comprising a thin conducting film supporting surface plasmon formation. In addition, the present invention provides methods and device for generating surface plasmons in a probe region and characterizing the composition of the probe region by generating one or more surface plasmon resonances curves and/or surface plasmon resonance images of the probe region.
FILED Tuesday, October 28, 2003
APPL NO 10/696738
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
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Department of Defense (DOD) 

US 07028688 Grove et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Corey M. Grove (Red Lion, Pennsylvania);  Stephen E. Chase (Jarrettsville, Maryland)
ABSTRACT A chemical-biological protective mask having a weight distribution that imparts a balanced center-of-gravity to the wearer of the mask, and is adaptable for different operational requirements by adjusting or altering the air flow through the mask. The protective mask includes a head covering to fully cover the wearer's head including a hood, a face piece having a visor contoured to the wearer's face, ducting within the mask connected to a filtering system mounted at the rear of the head covering and a purge airflow through the hood. Additional side or front mounted filters can be added to provide either parallel or series filtration with the rear mounted filters. A blower system may also be used to impart an airflow into the mask and improve breathing resistance.
FILED Tuesday, April 05, 2005
APPL NO 11/100233
ART UNIT 3743 — SELECT * FROM codes_techcenter;
CURRENT CPC
Surgery
128/201.250
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US 07028951 Sadeck
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) James E. Sadeck (East Freetown, Massachusetts)
ABSTRACT The present invention is directed to a parachute reefing system having a flexible ring section. The flexible ring section has a circumference. The reefing system includes a plurality of equidistantly spaced loops attached to the flexible ring section and a plurality of link members wherein each link member is attached to a corresponding loop and sized to allow at least one suspension line to pass therethrough. The reefing system also has a cross-connecting section comprising pair of intersecting members that are attached to the flexible ring section. The intersecting members are attached to each other at an intersection point that is coincident with the center of flexible ring section. The reefing system has a position cord having a first end attached to the intersection point and a second end opposite the first end. A yoke is attached to the second end of the position cord and has a vertex and at least two legs that extend from the vertex. Each leg extends from the vertex to a distal end. A riser link is attached to the distal end of each leg.
FILED Wednesday, April 20, 2005
APPL NO 11/110277
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/152
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US 07029174 Mattingly, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Bernard I. Mattingly, Jr. (Leonardtown, Maryland);  Miguel A. DeLeon (Waldorf, Maryland);  Charles D. Pipes, Jr. (Hughesville, Maryland)
ABSTRACT A method and apparatus for holding multiple x-ray cassettes for imaging a target including multiple layers of x-ray cassettes wherein the x-ray cassettes in successive layers are positioned in partial overlapping relationship such that when the target and x-ray cassettes are exposed to x-rays, a continuous image of the target is obtained.
FILED Tuesday, January 07, 2003
APPL NO 10/337318
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/174
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US 07029534 Archer, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Harry L. Archer, Jr. (Alexandria, Virginia)
ABSTRACT An apparatus for spreading liquid liner in the interior of a rocket motor tube, the rocket motor tube having masks attached at both ends of the rocket motor tube, the apparatus including a generally vertical support plate with an opening there through; a flange with a center opening attached to the support plate; a support tube inserted into the center opening of the flange; a stop disposed in the support tube, the stop abutting the support plate and engaging a mask on one end of the rocket motor tube; a retaining funnel that engages a mask on the other end of the rocket motor tube; a retaining ring that threadingly engages the retaining funnel; and at least two clamps attached to the support tube and engaging the retaining ring.
FILED Wednesday, November 10, 2004
APPL NO 10/985064
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Coating apparatus
118/500
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US 07029603 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) University of Dayton (Dayton, Ohio)
INVENTOR(S) Chyi-Shan Wang (Beavercreek, Ohio);  Max D. Alexander (Centerville, Ohio)
ABSTRACT A method of reinforcing a polymeric material with carbon nanofibers is provided in which carbon nanofibers are combined with a polymer and a solvent for the polymer to form a substantially homogeneous mixture, followed by removal of the solvent by evaporation or coagulation. The resulting conductive polymeric nanocomposite material exhibits high electrical and thermal conductivity, enhanced mechanical strength, abrasion resistance, and dimensional stability.
FILED Friday, October 31, 2003
APPL NO 10/698218
ART UNIT 1751 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions
252/511
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US 07029613 Wan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Julin Wan (Schenectady, New York);  Matthew J. Gasch (Sacramento, California);  Amiya K. Mukherjee (Davis, California)
ABSTRACT Densified composites of silicon nitride and silicon carbide that exhibit high creep resistance are obtained by mechanically activating a mixture of amorphous powders of silicon nitride and silicon carbide and sintering the mechanically activated mixture in the presence of an electric field under high pressure. The grain size in the resulting composite is less than 100 nanometers for all components of the composite, and the composite exhibits high creep resistance.
FILED Monday, September 08, 2003
APPL NO 10/658126
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/123
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029685 Lanar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) David E. Lanar (Takoma Park, Maryland);  Sheetij Dutta (Silver Spring, Maryland);  Lisa A. Ware (Silver Spring, Maryland);  Lalitha P. V. Nair (New Delhi, India)
ABSTRACT In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in antibody production, and as a protein for use alone, or as part of, a vaccine to prevent malaria.
FILED Tuesday, October 15, 2002
APPL NO 10/271145
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/272.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029853 Rastogi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Vipin K. Rastogi (Bel Air, Maryland);  Tu-Chen Cheng (Timonium, Maryland)
ABSTRACT The invention provides purified and isolated DNA fragments from Bacillus anthracis chromosomal DNA, primer sets and probes derived therefrom, as well as kits and detection methods for B. anthracis. The methods of the invention provide for specific detection of anthrax over closely related strains of Bacillus, as well as accurate detection of low numbers of B. anthracis in an environmental sample containing large amounts of non-specific DNA. The invention is applicable to food, health care, and military applications.
FILED Monday, September 09, 2002
APPL NO 10/241386
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07029996 Im et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) James S. Im (New York, New York);  Robert S. Sposili (New York, New York);  Mark A. Crowder (New York, New York)
ABSTRACT Methods for processing an amorphous silicon thin film sample into a polycrystalline silicon thin film are disclosed. In one preferred arrangement, a method includes the steps of generating a sequence of excimer laser pulses, controllably modulating each excimer laser pulse in the sequence to a predetermined fluence, homoginizing each modulated laser pulse in the sequence in a predetermined plane, masking portions of each homoginized fluence controlled laser pulse in the sequence with a two dimensional pattern of slits to generate a sequence of fluence controlled pulses of line patterned beamlets, each slit in the pattern of slits being sufficiently narrow to prevent inducement of significant nucleation in region of a silicon thin film sample irradiated by a beamlet corresponding to the slit, irradiating an amorphous silicon thin film sample with the sequence of fluence controlled slit patterned beamlets to effect melting of portions thereof corresponding to each fluence controlled patterned beamlet pulse in the sequence of pulses of patterned beamlets, and controllably sequentially translating a relative position of the sample with respect to each of the fluence controlled pulse of slit patterned beamlets to thereby process the amorphous silicon thin film sample into a single or polycrystalline silicon thin film.
FILED Wednesday, November 13, 2002
APPL NO 10/294001
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/487
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US 07030370 Crookston et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Matthew Crookston (Rangely, Colorado);  Michael Robinson (Groton, Massachusetts);  Paul Baker (Leominster, Massachusetts)
ABSTRACT A microchip ring trap for cold atoms or neutral molecules consists of a particular multi-layer layout of wires on a microchip. These conductive wires may be produced by photolithography on a substrate (e.g. gold on sapphire). There are four wires crucial to the design, essentially a pair of “two-wire waveguides”. These wires are laid out on concentric circles with the inner and outer most wires on lower level of the chip, and the middle pair of wires on the top layer (the chip surface).
FILED Tuesday, February 22, 2005
APPL NO 11/070404
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/251
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US 07030452 Tao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents (Tempe, Arizona)
INVENTOR(S) Nongjian Tao (Phoenix, Arizona);  Salah Boussaad (Tempe, Arizona)
ABSTRACT A method for forming atomic-scale contacts and atomic-scale gaps between two electrodes is disclosed. The method provides for applying a voltage between two electrodes in a circuit with a resistor. The applied voltage etches metal ions off one electrode and deposits the metal ions onto the second electrode. The metal ions are deposited on the sharpest point of the second electrode, causing the second electrode to grow towards the first electrode until an atomic-scale contact is formed. By increasing the magnitude of the resistor, the etching and deposition process will terminate prior to contact, forming an atomic-scale gap. The atomic-scale contacts and gaps formed according to this method are useful as a variety of nanosensors including chemical sensors, biosensors, hydrogen ion sensors, heavy metal ion sensors, magnetoresistive sensors, and molecular switches.
FILED Thursday, March 04, 2004
APPL NO 10/795151
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/414
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US 07030470 Ho et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) SUN Microsystems, Inc. (Santa Clara, California)
INVENTOR(S) Ronald Ho (Mountain View, California);  Robert J. Drost (Mountain View, California);  Chih-Kong Ken Yang (Santa Monica, California)
ABSTRACT One embodiment of the present invention provides a system that operatively couples an integrated circuit with a microstrip transmission line through chip lamination. The system includes a first semiconductor die containing the integrated circuit, and a second semiconductor die containing the microstrip transmission line. Unlike metal lines in the integrated circuit, which have relatively small cross-sections, the microstrip transmission line has a cross-section that is large enough so that signal propagation is governed by inductance and capacitance (LC) instead of resistance and capacitance (RC). The first semiconductor die and the second semiconductor die are laminated together so that the integrated circuit on the first semiconductor die is operatively coupled with the microstrip transmission line in the second semiconductor die.
FILED Tuesday, May 11, 2004
APPL NO 10/844196
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/662
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US 07030579 Schmitz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John J. Schmitz (Saint Clair Shores, Michigan);  Paul A. Petrovich (Fowlerville, Michigan);  A. David Stormer (Clinton Twp., Michigan);  Robert G. Washburn (Sterling Heights, Michigan)
ABSTRACT A mechanism for retrofitting a turret that has a manual rotation system with a motorized turret rotation system includes a gear box mechanically coupled to the turret, an electrically powered prime mover unit mechanically coupled to the gear box, a user operated control device electrically coupled to the prime mover unit, and an electrical power supply electrically coupled to the prime mover unit. The turret rotates relative to a body structure. The gear box and the prime mover unit are mounted to the body structure. The control device and the electrical power supply are positioned on the turret. The power supply provides electrical power to the prime mover. The control device presents a control signal to the prime mover when the user actuates the control device, and the turret rotates in response to the control signal.
FILED Tuesday, May 31, 2005
APPL NO 11/151190
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Motive power systems
318/139
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US 07030621 Sarkozi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Janos Gyorgy Sarkozi (Niskayuna, New York);  Nicole Andrea Evers (Niskayuna, New York)
ABSTRACT A system and method for detecting partial discharges or arcing in wiring or cables is disclosed. The system employs a high-voltage AC power source to generate a high-voltage low-current AC waveform, which is propagated through a selected wire, which in turn, produces the return signal. The return signal is processed using a signal processor and the analyzed for indications of the occurrence of a partial discharge. The method detects damage to a selected wire by utilizing high voltage, low current AC waveforms to induce partial discharges in a controlled manner and detecting a return signal resulting from the discharge.
FILED Tuesday, May 04, 2004
APPL NO 10/838474
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/536
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030808 Repperger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Daniel W. Repperger (Dayton, Ohio);  Eric M. Alderman (Gresham, Oregon);  M. Seddik Djouadi (Knoxville, Tennessee)
ABSTRACT Nonlinear target detection for the detection of extremely weak signals when buried in very high levels of noise is performed with improvement of the quality of the signals received in the data by the amplification of the signal to noise (S/N) ratio. The S/N ratio increases dramatically after the originally measured signal is passed through a nonlinear stochastic resonance filter.
FILED Friday, March 05, 2004
APPL NO 10/794547
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/159
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030809 McCabe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as representd by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) D. Hugh McCabe (Fredericksburg, Virginia);  A. Sunshine Smith-Carroll (Spotsylvania, Virginia)
ABSTRACT A multiple model (MM) radar tracking filter which controls the weighting applied to outputs of first and second model functions responsive to non-Markovian switching logic, includes the first and second model functions, switching logic receiving unweighted outputs from the first and second model functions and generating first and second weighting signals, first and second multipliers generating respective first and second weighted output signals responsive to received ones of the unweighted outputs of the first and second model functions and the first and second weighting signals, and a feed back loop for providing a feedback signal to respective inputs of the first and second model functions responsive to the weighted outputs of the first and second multipliers. If desired, the MM radar tracking filter may also include a summer for generating a signal output responsive to the weighted outputs of the first and second multipliers. A method for controlling the MM radar tracking filter employing alternatives (non-Markov) switching logic is also described.
FILED Friday, November 14, 2003
APPL NO 10/716978
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/195
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US 07030971 Payton
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Michael Payton (Portsmouth, Rhode Island)
ABSTRACT A CW lightwave modulated by a continuously reiterated binary pseudorandom code sequence is launched into an end of a span of ordinary optical fiber cable. Portions of the launched lightwave back propagate to the launch end from a continuum of locations along the span because of innate fiber properties including Rayleigh scattering. This is picked off the launch end and heterodyned to produce a r.f. beat signal. The r.f. beat signal is processed by a plurality (which can be thousands) of correlator type binary pseudonoise code sequence demodulators respectively operated in different delay time relationships to the timing base of the reiterated modulation sequences. The outputs of the demodulators provide r.f. time-domain reflectometry outputs representative of signals (e.g., acoustic pressure waves) incident to virtual sensors along the fiber at positions corresponding to the various time delay relationships.
FILED Monday, February 07, 2005
APPL NO 11/056630
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/35.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030997 Neureuther et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Andrew R. Neureuther (Berkeley, California);  Kostas Adam (Berkeley, California);  Garth C. Robins (Berkeley, California);  Frank E. Gennari (Berkeley, California)
ABSTRACT Aberrations in a lens and lens system are identified by projecting an optical beam through a mask having an opening (probe) and a surrounding open geometry (pattern) and through the lens to an image plane. Lens aberrations are identified from the combined intensity of the beam in the image plane. In one embodiment the pattern is a plurality of rings concentric with the probe. Spillover between the probe and the geometry becomes intermixed in passing through the lens and alters the light intensity in the image plane. Vision of a patient can be tested by providing a plurality of probe openings and surrounding geometries that are illuminated. The patient then compares the images for brighter and darker probes as a measure of pupil aberrations. Areas in an integrated circuit mask layout impacted by aberrations in projection printing can be identified by sequentially comparing an aberration function to a mask layout, which can then be used to modify the mask layout.
FILED Tuesday, September 10, 2002
APPL NO 10/241242
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/515
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031054 Cathey, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) The Regent of the University of Colorado (Boulder, Colorado)
INVENTOR(S) Wade Thomas Cathey, Jr. (Boulder, Colorado);  Edward Raymond Dowski, Jr. (Lafayette, Colorado);  Sherif S. Sherif (London, United Kingdom)
ABSTRACT An imaging system for imaging an object onto an image plane. An optical arrangement forms an intermediate image of the object at an intermediate plane with a first value of axial resolution. The imaging system also includes a digital processor configured to process the intermediate image to form a final image of the object. The imaging system further includes a specially designed optical element that cooperates with the optical arrangement and the digital processor to define a second value of axial resolution that is greater than the first value.
FILED Thursday, October 09, 2003
APPL NO 10/682014
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/363
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031265 Owen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Sarnoff Corporation (Princeton, New Jersey)
INVENTOR(S) Henry Spyker Owen (Medford, New Jersey);  Chad Michael Hawes (Burlington, New Jersey)
ABSTRACT A method and apparatus for performing packet processing is described. A signal having a preamble sequence is received. A detection parameter estimate is derived from the preamble sequence. The detection parameter estimate is evaluated to process at least one packet in the signal.
FILED Friday, September 24, 2004
APPL NO 10/949001
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Multiplex communications
370/252
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031288 Ogier
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Richard G. Ogier (Half Moon Bay, California)
ABSTRACT A protocol for discovering a new neighbor node and detecting the loss of an existing neighbor node in a network is described. A node receives a neighbor discovery message from a neighbor node. The node receiving the neighbor discovery message periodically transmits a predetermined number of neighbor discovery messages in response to the received neighbor discovery message. Each neighbor discovery message includes an identity of the neighbor node. After transmitting the predetermined number of neighbor discovery messages, the node transmits neighbor discovery messages that omit the identity of the neighbor node until another neighbor discovery message is received from the neighbor node that indicates a change in a communications state associated with the neighbor node.
FILED Friday, December 01, 2000
APPL NO 09/728192
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Multiplex communications
370/338
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031308 Garcia-Luna-Aceves et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) J. J. Garcia-Luna-Aceves (San Mateo, California);  Hans-Peter Dommel (Santa Cruz, California)
ABSTRACT A method for performing end-to-end “tree-based ordered multicasting” (TOM) which ensures collective integrity and consistency of distributed operations, and which is applicable to distributed multiparty collaboration and other multipoint applications. The TOM protocol performs cascaded total ordering of messages among on-tree hosts en route from senders to receivers, and does not require the building of a separate propagation graph to compute ordering information. TOM elects sequencer nodes dynamically based on address extensions of the multicast tree. Message ordering is performed by multicasting a message from each source node to receivers, unicasting a control message from a source node across a primary node to an ordering node for the designated multicast group or transmission in the tree, determining a binding sequence number for the message and a multicast to the receiver group, and delivering messages at end hosts according to the agreed-upon sequence numbers.
FILED Tuesday, October 30, 2001
APPL NO 10/035348
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Multiplex communications
370/390
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031365 Kneissl et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Stamford, Connecticut)
INVENTOR(S) Michael A. Kneissl (Mountain View, California);  Noble M. Johnson (Menlo Park, California);  David K. Biegelsen (Portola Valley, California);  Richard K. Chang (Hamden, Connecticut);  A. Douglas Stone (New Haven, Connecticut);  Grace D. Chern (New Haven, Connecticut);  Hakan E. Tureci (New Haven, Connecticut);  Joseph Zyss (Sceaux, France)
ABSTRACT A locally-outcoupled optical resonator has whispering gallery modes existing in a nearly circular resonator. Light is outcoupled by providing a local perturbing feature on the perimeter of the locally-outcoupled cavity resonator. The perturbing feature provides an outcoupling or loss mechanism that asymmetrically interacts with circulating whispering gallery modes, thereby making the resonator capable of uni-directional output.
FILED Friday, May 02, 2003
APPL NO 10/428068
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/94
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031577 Painter et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Xponent Photonics Inc (Monrovia, California)
INVENTOR(S) Oskar J. Painter (Pasadena, California);  David W. Vernooy (Sierra Madre, California);  Kerry J. Vahala (San Gabriel, California)
ABSTRACT A multi-layer laterally-confined dispersion-engineered optical waveguide may include one multi-layer reflector stack for guiding an optical mode along a surface thereof, or may include two multi-layer reflector stacks with a core therebetween for guiding an optical mode along the core. Dispersive properties of such multi-layer waveguides enable modal-index-matching between low-index optical fibers and/or waveguides and high-index integrated optical components and efficient transfer of optical signal power therebetween. Integrated optical devices incorporating such multi-layer waveguides may therefore exhibit low (<3 dB) insertion losses. Incorporation of an active layer (electro-optic, electro-absorptive, non-linear-optical) into such waveguides enables active control of optical loss and/or modal index with relatively low-voltage/low-intensity control signals. Integrated optical devices incorporating such waveguides may therefore exhibit relatively low drive signal requirements.
FILED Tuesday, November 16, 2004
APPL NO 10/990950
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07032166 Servi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Leslie David Servi (Lincoln, Massachusetts);  Eushiuan T. Tsung (Needham, Massachusetts);  Joseph Anthony Cooley (Burlington, Massachusetts);  Jeremy Mineweaser (Marina Del Ray, California)
ABSTRACT In one aspect, a technique is provided for protecting a data set with a parity set defined by a bipartite graph having a degree distribution that includes no parity symbol having a degree less than three. In another aspect, a parity set defined by an irregular bipartite graph is transmitted along with the data set, and corruptions in the data set are decoded using the data set and the parity set. In another aspect, a particularly useful degree distribution for the parity symbols is defined.
FILED Tuesday, December 03, 2002
APPL NO 10/308627
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Error detection/correction and fault detection/recovery
714/800
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07028481 Morrow
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Charles W. Morrow (Albuquerque, New Mexico)
ABSTRACT A modified, closed-loop Brayton cycle power conversion system that uses liquefied natural gas as the cold heat sink media. When combined with a helium gas cooled nuclear reactor, achievable efficiency can approach 68–76% (as compared to 35% for conventional steam cycle power cooled by air or water). A superheater heat exchanger can be used to exchange heat from a side-stream of hot helium gas split-off from the primary helium coolant loop to post-heat vaporized natural gas exiting from low and high-pressure coolers. The superheater raises the exit temperature of the natural gas to close to room temperature, which makes the gas more attractive to sell on the open market. An additional benefit is significantly reduced costs of a LNG revaporization plant, since the nuclear reactor provides the heat for vaporization instead of burning a portion of the LNG to provide the heat.
FILED Thursday, October 14, 2004
APPL NO 10/965577
ART UNIT 3748 — SELECT * FROM codes_techcenter;
CURRENT CPC
Power plants
060/649
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07028490 Tomlinson
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Batelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) John J. Tomlinson (Knoxville, Tennessee)
ABSTRACT A water-heating dehumidifier includes a refrigerant loop including a compressor, at least one condenser, an expansion device and an evaporator including an evaporator fan. The condenser includes a water inlet and a water outlet for flowing water therethrough or proximate thereto, or is affixed to the tank or immersed into the tank to effect water heating without flowing water. The immersed condenser design includes a self-insulated capillary tube expansion device for simplicity and high efficiency. In a water heating mode air is drawn by the evaporator fan across the evaporator to produce cooled and dehumidified air and heat taken from the air is absorbed by the refrigerant at the evaporator and is pumped to the condenser, where water is heated. When the tank of water heater is full of hot water or a humidistat set point is reached, the water-heating dehumidifier can switch to run as a dehumidifier.
FILED Friday, May 28, 2004
APPL NO 10/856521
ART UNIT 3744 — SELECT * FROM codes_techcenter;
CURRENT CPC
Refrigeration
062/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07028747 Widrig et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Siemens Power Generation, Inc. (Orlando, Florida)
INVENTOR(S) Scott M. Widrig (Hobe Sound, Florida);  Ronald J. Rudolph (Juno Beach, Florida);  Gregg P. Wagner (Apopka, Florida)
ABSTRACT An airfoil, a method of manufacturing an airfoil, and a system for cooling an airfoil is provided. The cooling system can be used with an airfoil located in the first stages of a combustion turbine within a combined cycle power generation plant and involves flowing closed loop steam through a pin array set within an airfoil. The airfoil can comprise a cavity having a cooling chamber bounded by an interior wall and an exterior wall so that steam can enter the cavity, pass through the pin array, and then return to the cavity to thereby cool the airfoil. The method of manufacturing an airfoil can include a type of lost wax investment casting process in which a pin array is cast into an airfoil to form a cooling chamber.
FILED Tuesday, December 03, 2002
APPL NO 10/308280
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Metal founding
164/369
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029203 Nickelson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Reva A. Nickelson (Shelley, Idaho);  John G. Richardson (Idaho Falls, Idaho);  Kevin M. Kostelnik (Idaho Falls, Idaho);  Paul A. Sloan (Rigby, Idaho)
ABSTRACT Systems, components, and methods relating to subterranean containment barriers. Laterally adjacent tubular casings having male interlock structures and multiple female interlock structures defining recesses for receiving a male interlock structure are used to create subterranean barriers for containing and treating buried waste and its effluents. The multiple female interlock structures enable the barriers to be varied around subsurface objects and to form barrier sidewalls. The barrier may be used for treating and monitoring a zone of interest.
FILED Tuesday, March 30, 2004
APPL NO 10/813810
ART UNIT 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Hydraulic and earth engineering
45/129.450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029574 Yang et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Ralph T. Yang (Ann Arbor, Michigan);  Frances H. Yang (Ann Arbor, Michigan);  Akira Takahashi (Yoko-Machi, Japan);  Arturo J. Hernandez-Maldonado (Ann Arbor, Michigan)
ABSTRACT A method for removing thiophene and thiophene compounds from liquid fuel includes contacting the liquid fuel with an adsorbent which preferentially adsorbs the thiophene and thiophene compounds. The adsorption takes place at a selected temperature and pressure, thereby producing a non-adsorbed component and a thiophene/thiophene compound-rich adsorbed component. The adsorbent includes either a metal or a metal ion that is adapted to form π-complexation bonds with the thiophene and/or thiophene compounds, and the preferential adsorption occurs by π-complexation. A further method includes selective removal of aromatic compounds from a mixture of aromatic and aliphatic compounds.
FILED Friday, March 21, 2003
APPL NO 10/393962
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Mineral oils: Processes and products
28/250
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029652 DeNardo et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Merck Patent GmbH (Darmstadt, Germany)
INVENTOR(S) Sally J. DeNardo (El Macerco, California);  Patricia A. Burke (Sacramento, California);  Gerald L. DeNardo (El Macerco, California);  Simon Goodman (Darmstadt, Germany);  Kerstin Matzku, legal representative (Zwingenberg, Germany)
ABSTRACT A method of treating tumors, such as prostate tumors, breast tumors, non-Hodgkin's lymphoma, and the like, includes the sequential steps of administering to the patient at least one dose of an antiangiogenic cyclo-arginine-glycine-aspartic acid-containing pentapeptide (cRGD pentapeptide); administering to the patient an anti-tumor effective amount of a radioimmunotherapeutic agent (RIT); and then administering to the patient at least one additional dose of cRGD pentapeptide. The cRGD pentapeptide is preferably cyclo-(Arg-Gly-Asp-D-Phe-[N-Me]-Val), and the RIT is preferably a radionuclide-labeled chelating agent-ligand complex in which chelating agent is chemically bonded to a tumor-targeting molecule, such as a monoclonal antibody.
FILED Wednesday, July 31, 2002
APPL NO 10/208931
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.490
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029721 Hasz et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Wayne Charles Hasz (Pownal, Vermont);  D Sangeeta (Cincinnati, Ohio)
ABSTRACT A method for applying a bond coat on a metal-based substrate is described. A slurry which contains braze material and a volatile component is deposited on the substrate. The slurry can also include bond coat material. Alternatively, the bond coat material can be applied afterward, in solid form or in the form of a second slurry. The slurry and bond coat are then dried and fused to the substrate. A repair technique using this slurry is also described, along with related compositions and articles.
FILED Tuesday, December 23, 2003
APPL NO 10/747553
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating processes
427/142
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029921 Lee et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Yin-Nan E. Lee (East Setauket, New York);  Rodney J. Weber (Atlanta, Georgia);  Douglas Orsini (Aubiere Cedex, France)
ABSTRACT An apparatus for continuous on-line measurement of chemical composition of aerosol particles with a fast time resolution is provided. The apparatus includes an enhanced particle size magnifier for producing activated aerosol particles and an enhanced collection device which collects the activated aerosol particles into a liquid stream for quantitative analysis by analytical means. Methods for on-line measurement of chemical composition of aerosol particles are also provided, the method including exposing aerosol carrying sample air to hot saturated steam thereby forming activated aerosol particles; collecting the activated aerosol particles by a collection device for delivery as a jet stream onto an impaction surface; and flushing off the activated aerosol particles from the impaction surface into a liquid stream for delivery of the collected liquid stream to an analytical instrument for quantitative measurement.
FILED Thursday, October 24, 2002
APPL NO 10/279510
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Analytical and immunological testing
436/148
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030071 Hoffman et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dennis M. Hoffman (Livermore, California);  Ing Lap Chiu (Castro Valley, California)
ABSTRACT Formation of solid-water detoxifying reagents for chemical and biological agents. Solutions of detoxifying reagent for chemical and biological agents are coated using small quantities of hydrophobic nanoparticles by vigorous agitation or by aerosolization of the solution in the presence of the hydrophobic nanoparticles to form a solid powder. For example, when hydrophobic fumed silica particles are shaken in the presence of IN oxone solution in approximately a 95:5-weight ratio, a dry powder results. The hydrophobic silica forms a porous coating of insoluble fine particles around the solution. Since the chemical or biological agent tends to be hydrophobic on contact with the weakly encapsulated detoxifying solution, the porous coating breaks down and the detoxifying reagent is delivered directly to the chemical or biological agent for maximum concentration at the point of need. The solid-water (coated) detoxifying solutions can be blown into contaminated ventilation ducting or other difficult to reach sites for detoxification of pools of chemical or biological agent. Once the agent has been detoxified, it can be removed by flushing the area with air or other techniques.
FILED Tuesday, February 26, 2002
APPL NO 10/085512
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Cleaning compositions for solid surfaces, auxiliary compositions therefor, or processes of preparing the compositions
510/110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030355 Bochenski et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia National Laboratories (Livermore, California)
INVENTOR(S) Edwin B. Bochenski (Tracy, California);  Jack L. Skinner (Brentwood, California);  Paul M. Dentinger (Sunol, California);  Scott C. Lindblom (Tracy, California)
ABSTRACT An electrical circuit for a photomultiplier tube (PMT) is disclosed that reduces power consumption to a point where the PMT may be powered for extended periods with a battery. More specifically, the invention concerns a PMT circuit comprising a low leakage switch and a high voltage capacitor positioned between a resistive divider and each of the PMT dynodes, and a low power control scheme for recharging the capacitors.
FILED Tuesday, August 03, 2004
APPL NO 10/910853
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/207
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030398 Tajima
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Toshiki Tajima (Alamo, California)
ABSTRACT A system and method of accelerating ions in an accelerator to optimize the energy produced by a light source. Several parameters may be controlled in constructing a target used in the accelerator system to adjust performance of the accelerator system. These parameters include the material, thickness, geometry and surface of the target.
FILED Tuesday, March 01, 2005
APPL NO 11/070074
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/505.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030411 Krulevitch et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Peter A. Krulevitch (Pleasanton, California);  Mariam N. Maghribi (Livermore, California);  William J. Benett (Livermore, California);  Julie K. Hamilton (Tracy, California);  Klint A. Rose (Mt. View, California);  James Courtney Davidson (Livermore, California);  Mark S. Strauch (Livermore, California)
ABSTRACT A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.
FILED Monday, September 13, 2004
APPL NO 10/939771
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/57
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030624 Love
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Frank Love (Amarillo, Texas)
ABSTRACT An electrical circuit testing device is provided, comprising a case, a digital voltage level testing circuit with a display means, a switch to initiate measurement using the device, a non-shorting switching means for selecting pre-determined electrical wiring configurations to be tested in an outlet, a terminal block, a five-pole electrical plug mounted on the case surface and a set of adapters that can be used for various multiple-pronged electrical outlet configurations for voltages from 100–600 VAC from 50–100 Hz.
FILED Thursday, February 17, 2005
APPL NO 11/059861
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Electricity: Measuring and testing
324/555
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030805 Ormesher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) SANDIA Corporation (Albuquerque, New Mexico)
INVENTOR(S) Richard C. Ormesher (Albuquerque, New Mexico);  Robert M. Axline (Albuquerque, New Mexico)
ABSTRACT Methods and systems reduce clutter interference in a radar-responsive tag system. A radar transmits a series of linear-frequency-modulated pulses and receives echo pulses from nearby terrain and from radar-responsive tags that may be in the imaged scene. Tags in the vicinity of the radar are activated by the radar's pulses. The tags receive and remodulate the radar pulses. Tag processing reverses the direction, in time, of the received waveform's linear frequency modulation. The tag retransmits the remodulated pulses. The radar uses a reversed-chirp de-ramp pulse to process the tag's echo. The invention applies to radar systems compatible with coherent gain-block tags. The invention provides a marked reduction in the strength of residual clutter echoes on each and every echo pulse received by the radar. SAR receiver processing effectively whitens passive-clutter signatures across the range dimension. Clutter suppression of approximately 14 dB is achievable for a typical radar system.
FILED Friday, July 23, 2004
APPL NO 10/898119
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/42
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030981 Bishop et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regentsof the University of California (Oakland, California)
INVENTOR(S) James K. Bishop (Berkeley, California);  Christopher K. Guay (San Francisco, California)
ABSTRACT A method and apparatus for measuring birefringent particles is provided comprising a source lamp, a grating, a first polarizer having a first transmission axis, a sample cell and a second polarizer having a second polarization axis. The second polarizer has a second polarization axis that is set to be perpendicular to the first polarization axis, and thereby blocks linearly polarized light with the orientation of the beam of light passing through the first polarizer. The beam of light passing through the second polarizer is measured using a detector.
FILED Friday, August 09, 2002
APPL NO 10/215518
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/368
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031420 Jenkins et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Silicon Graphics, Inc. (Mountainview, California)
INVENTOR(S) Philip Nord Jenkins (Bau Claire, Wisconsin);  Frank N. Cornett (Chippewa Falls, Wisconsin)
ABSTRACT A system and method of reducing skew between a plurality of signals transmitted with a transmit clock is described. Skew is detected between the received transmit clock and each of received data signals. Delay is added to the clock or to one or more of the plurality of data signals to compensate for the detected skew. Each of the plurality of delayed signals is compared to a reference signal to detect changes in the skew. The delay added to each of the plurality of delayed signals is updated to adapt to changes in the detected skew.
FILED Thursday, December 30, 1999
APPL NO 09/476678
ART UNIT 2637 — Optical Communications
CURRENT CPC
Pulse or digital communications
375/371
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07032190 Auracher et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) LSI Logic Corporation (Milpitas, California)
INVENTOR(S) Stefan Auracher (Baierbrunn, Germany);  Claus Pribbernow (München, Germany);  Andreas Hils (Unterhaching, Germany)
ABSTRACT A representation of a macro for an integrated circuit layout. The representation may define sub-circuit cells of a module. The module may have a predefined functionality. The sub-circuit cells may include at least one reusable circuit cell. The reusable circuit cell may be configured such that when the predefined functionality of the module is not used, the reusable circuit cell is available for re-use.
FILED Monday, December 01, 2003
APPL NO 10/724996
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/1
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07029574 Yang et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Ralph T. Yang (Ann Arbor, Michigan);  Frances H. Yang (Ann Arbor, Michigan);  Akira Takahashi (Yoko-Machi, Japan);  Arturo J. Hernandez-Maldonado (Ann Arbor, Michigan)
ABSTRACT A method for removing thiophene and thiophene compounds from liquid fuel includes contacting the liquid fuel with an adsorbent which preferentially adsorbs the thiophene and thiophene compounds. The adsorption takes place at a selected temperature and pressure, thereby producing a non-adsorbed component and a thiophene/thiophene compound-rich adsorbed component. The adsorbent includes either a metal or a metal ion that is adapted to form π-complexation bonds with the thiophene and/or thiophene compounds, and the preferential adsorption occurs by π-complexation. A further method includes selective removal of aromatic compounds from a mixture of aromatic and aliphatic compounds.
FILED Friday, March 21, 2003
APPL NO 10/393962
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Mineral oils: Processes and products
28/250
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029624 Orme-Marmerelis et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Melissa Orme-Marmerelis (Irvine, California);  Robert F. Smith (Costa Mesa, California)
ABSTRACT In a high-speed fabrication process for producing highly uniform metallic microspheres, a molten metal is passed through a small orifice, producing a stream of molten metal therefrom. A series of molten metal droplets forms from the break up of the capillary stream. To achieve high uniformity of the spheres and avoid defects, the droplets are cooled before being captured. Separating the droplets, by causing them to travel in different paths than their adjacent droplets, helps to facilitate the cooling of the droplets. The droplets can be separated by electrostatically charging them as they break off from the capillary stream. The droplets are then passed through an electric field, which can be produced by a pair of deflection plates. The droplets are dispersed by varying the electric field—e.g., by rotating the plates or by varying the voltage applied thereto—or by varying the electrostatic charge of the droplets. Advantageously, the droplets can be actively cooled in flight by passing them through a cryogenic gas chamber.
FILED Thursday, April 03, 2003
APPL NO 10/407053
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Metallurgical apparatus
266/202
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029630 Kostov
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Maryland, Baltimore County (Baltimore, Maryland)
INVENTOR(S) Iordan V. Kostov (Baltimore, Maryland)
ABSTRACT The present invention relates to optical ion sensors, including fluorescence optical ion sensors for use in liquid media in the fields of biology, biotechnology, chemistry, medicine, etc. The present invention provides for optical ion sensors that may be attached to dry hydrophilic or hydrophobic surfaces so as to allow continuous sensing. The optical sensors of the present invention may be sterilized and stored for extended periods of time before use.
FILED Wednesday, June 30, 2004
APPL NO 10/879351
ART UNIT 2881 — Optics
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/82.60
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029688 Hubbell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jeffrey A. Hubbell (Zurich, Switzerland);  Natalie D. Winblade (Seattle, Washington);  Donald L. Elbert (St. Louis, Missouri)
ABSTRACT The invention discloses materials that adsorb readily to the surfaces of body tissues in situ and provide a steric barrier between such tissues, so that tissue adhesions, which typically form following surgical procedures, are minimized. These materials contain a polymer of hydrophilic molecules such as polyethylene glycol (PEG) bound to a polymer that spontaneously adsorbs to biological tissue such as phenylboronic acid (PBA). The PEG-PBA co-polymer can be formed in a variety of geometries. The materials can also be used to coat prosthetics and other implants.
FILED Friday, March 28, 2003
APPL NO 10/403344
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/422
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029697 Segura et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tatiana Segura (Evanston, Illinois);  Lonnie D. Shea (Evanston, Illinois);  Angela Kaye Pannier (Glenview, Illinois);  Zain Bengali (Naperville, Illinois);  Jae-Hyung Jang (Skokie, Illinois);  Peter Chung (Montgomery, Alabama);  Brian C. Anderson (Libertyville, Illinois)
ABSTRACT A system and methods for controlled gene delivery comprising condensed nucleic acids complexed with polylinkers, wherein the complexes are covalently and/or non-covalently bound to the surface of a substrate capable of supporting cell adhesion. The gene delivery system achieves temporal and spatial control of nucleic acid delivery to a target cell or cells through control of complex density on the surface of the support substrate, and reversibility of the attachment of the polylinker to the support substrate. The system and method of the invention can be used to create spatial patterns of gene expression, and in tissue engineering, high throughput screening, and gene therapy applications.
FILED Thursday, July 15, 2004
APPL NO 10/893572
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029829 Stark et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Brian H. Stark (Ann Arbor, Michigan);  Khalil Najafi (Ann Arbor, Michigan)
ABSTRACT A low temperature method for forming a microcavity on a substrate and article having same are provided which utilize electroplated films. The method is particularly useful to package microelectromechanical systems (MEMS) in vacuum on the wafer level and provide sealed feedthroughs to the outside world. The method may be performed in a batch process to substantially reduce cost and to form metal diaphragms. Furthermore, the method is performed at near room temperature, which provides more flexibility in the manufacturing process. The method enables substantial cost savings in the production of vacuum-sealed MEMS. Many feedthroughs can be incorporated into the package to transfer signals in and out of the package. One significant advantage of this method is that it does not require bonding of a second substrate, which reduces the system cost.
FILED Wednesday, April 16, 2003
APPL NO 10/417301
ART UNIT 1756 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029851 Heckel et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) David G. Heckel (Carlton, Australia);  Linda J. Gahan (Clemson, South Carolina)
ABSTRACT Nucleic acid (DNA) probes are provided which will specifically identify a gene for resistance of Bt in insect populations. Sequences are identified associated with the onset of resistance to Bacillus thuringiensis toxins. The sequences are used as probes to monitor the presence of acquired insect resistance associated with transgenic crops.
FILED Friday, March 15, 2002
APPL NO 10/098916
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030051 Davies
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Huw M. L. Davies (Clarence Center, New York)
ABSTRACT Disclosed is method for increasing the efficiency of a dirhodium catalyst. The method includes providing a dirhodium catalyst, providing an organic ester, and contacting the dirhodium catalyst and the organic ester under conditions effective to increase the efficiency of the dirhodium catalyst. The organic ester is selected such that it is not a substrate for catalysis by the dirhodium catalyst. Dirhodium catalyst compositions which include a dirhodium catalyst and an organic ester are also disclosed. In these compositions, the organic ester is not a substrate for catalysis by the dirhodium catalyst. The method and compositions can be used in a number of reactions, including insertion reactions (e.g., C—H insertions, Si—H insertions, O—H insertions, and N—H insertions) cyclopropanation reactions, annulations (e.g., [3+2] annulations and [3+4] annulations), and ω,ω-diarylalkanoate syntheses.
FILED Tuesday, August 27, 2002
APPL NO 10/229378
ART UNIT 1755 — Semiconductors/Memory
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030452 Tao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents (Tempe, Arizona)
INVENTOR(S) Nongjian Tao (Phoenix, Arizona);  Salah Boussaad (Tempe, Arizona)
ABSTRACT A method for forming atomic-scale contacts and atomic-scale gaps between two electrodes is disclosed. The method provides for applying a voltage between two electrodes in a circuit with a resistor. The applied voltage etches metal ions off one electrode and deposits the metal ions onto the second electrode. The metal ions are deposited on the sharpest point of the second electrode, causing the second electrode to grow towards the first electrode until an atomic-scale contact is formed. By increasing the magnitude of the resistor, the etching and deposition process will terminate prior to contact, forming an atomic-scale gap. The atomic-scale contacts and gaps formed according to this method are useful as a variety of nanosensors including chemical sensors, biosensors, hydrogen ion sensors, heavy metal ion sensors, magnetoresistive sensors, and molecular switches.
FILED Thursday, March 04, 2004
APPL NO 10/795151
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/414
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031561 Lim et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Desmond R. Lim (Cambridge, Massachusetts);  Lionel C. Kimerling (Concord, Massachusetts)
ABSTRACT A chip for integrating functions performed by micro-optics and RF circuits including at least one optical function module that receives an optical signal and performs at least one of a plurality of optical functions. A RF function module that receives a RF signal and perform at least one of a plurality of RF functions. The at least one optical function module and the RF function module provides a monolithic integration of optics and RF circuits on the chip.
FILED Friday, June 21, 2002
APPL NO 10/177428
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031770 Collins et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Cardiac Pacemakers, Inc. (Saint Paul, Minnesota)
INVENTOR(S) Kevin Collins (Minneapolis, Minnesota);  Milton M. Morris (Minneapolis, Minnesota);  Alan F. Marcovecchio (Woodbury, Minnesota)
ABSTRACT An implantable heart-monitoring device designed to distinguish two differing heart rhythms. The device comprises electrodes, a template, and first, second and third electronic mechanisms. The first electronic mechanism converts electrical representations of heartbeats from the electrodes into digital data and performs calculations including at least a partial discrete wavelet transform upon the digital data to generate a subset of discrete wavelet transform components including components for distinguishing the two differing heart rhythms and also demonstrated to be relatively low in variability from one patient to another. The template contains a corresponding subset of discrete wavelet transform components captured from at least one individual whose heart was beating in accordance with one of the two differing heart rhythms. The second electronic mechanism correlates the subset of transform components against the template components and provides a correlation value. The third electronic mechanism mathematically examines a time series of the correlation values and gives an indication of whether the first or second of the heart rhythms is present.
FILED Tuesday, December 31, 2002
APPL NO 10/334651
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/5
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07029561 Ross et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Commerce (Washington, District of Columbia)
INVENTOR(S) David Ross (Silver Spring, Maryland);  Laurie E. Locascio (North Potomac, Maryland)
ABSTRACT A method and device are provided for concentrating and separating ionic species in solution within a fluidic device having a fluid conduit such as a channel or capillary. The concentration is achieved by balancing the electrophoretic velocity of an analyte against the bulk flow of solution in the presence of a temperature gradient. Using an appropriate buffer, the temperature gradient can generate a corresponding gradient in the electrophoretic velocity so that the electrophoretic and bulk velocities sum to zero at a unique point and the analyte will be focused at that point. The method and device may be adapted for use with a variety of analytes including fluorescent dyes, amino acids, proteins, DNA and to concentrate a dilute analyte.
FILED Thursday, July 18, 2002
APPL NO 10/197331
ART UNIT 1753 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry: Electrical and wave energy
24/451
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07029646 Margrave et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
Non-Profit Organization (NPO)
Robert A. Welch Foundation
APPLICANT(S)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) John L. Margrave (Bellaire, Texas);  Zhenning Gu (Houston, Texas);  Robert H. Hauge (Houston, Texas);  Richard E. Smalley (Houston, Texas)
ABSTRACT A method for cutting single-wall carbon nanotubes involves partially fluorinating single-wall carbon nanotubes and pyrolyzing the partially fluorinated nanotubes in an inert atmosphere or vacuum up to about 1000° C. The nanotubes are optionally purified before cutting. The partial fluorination involves fluorinating the nanotubes to a carbon-fluorine stoichiometry of CFx, where x is up to about 0.3. The invention also relates to the derivatization of fluorinated and cut single-wall carbon nanotubes. The single-wall carbon nanotubes can be cut to any length depending on the fluorination and pyrolysis conditions. Short nanotubes are useful in various applications, such as field emitters for flat panel displays and as “seeds” for further nanotube growth.
FILED Tuesday, April 08, 2003
APPL NO 10/408886
ART UNIT 1754 — Optics
CURRENT CPC
Chemistry of inorganic compounds
423/447.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031553 Myers et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Research and Development Activity (ARDA)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Gregory K. Myers (San Francisco, California);  Robert C. Bolles (Mountain View, California);  Quang-Tuan Luong (Menlo Park, California);  James A. Herson (Emerald Hills, California)
ABSTRACT An apparatus and a concomitant method for detecting and recognizing text information in a captured imagery. The present method transforms the image of the text to a normalized coordinate system before performing OCR, thereby yielding more robust recognition performance. The present invention also combines OCR results from multiple frames, in a manner that takes the best recognition results from each frame and forms a single result that can be more accurate than the results from any of the individual frames.
FILED Friday, June 29, 2001
APPL NO 09/895868
ART UNIT 2625 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/289
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031796 Lange
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) KLA-Tencor Technologies Corporation (Milpitas, California)
INVENTOR(S) Steven R. Lange (Alamo, California)
ABSTRACT A method for limiting exposure of a substrate to potentially damaging radiation from a radiating apparatus. A database of information associated with the substrate is compiled, and the substrate is identified prior to processing the substrate on the radiating apparatus. The database of information associated with the substrate is accessed, including its past irradiation history of dosage and type of irradiation, based on the substrate identification, and the operation of the radiating apparatus is selectively modified based at least in part on the information associated with the substrate.
FILED Wednesday, September 03, 2003
APPL NO 10/654082
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Generic control systems or specific applications
7/123
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 07031308 Garcia-Luna-Aceves et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) J. J. Garcia-Luna-Aceves (San Mateo, California);  Hans-Peter Dommel (Santa Cruz, California)
ABSTRACT A method for performing end-to-end “tree-based ordered multicasting” (TOM) which ensures collective integrity and consistency of distributed operations, and which is applicable to distributed multiparty collaboration and other multipoint applications. The TOM protocol performs cascaded total ordering of messages among on-tree hosts en route from senders to receivers, and does not require the building of a separate propagation graph to compute ordering information. TOM elects sequencer nodes dynamically based on address extensions of the multicast tree. Message ordering is performed by multicasting a message from each source node to receivers, unicasting a control message from a source node across a primary node to an ordering node for the designated multicast group or transmission in the tree, determining a binding sequence number for the message and a multicast to the receiver group, and delivering messages at end hosts according to the agreed-upon sequence numbers.
FILED Tuesday, October 30, 2001
APPL NO 10/035348
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Multiplex communications
370/390
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07032166 Servi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Leslie David Servi (Lincoln, Massachusetts);  Eushiuan T. Tsung (Needham, Massachusetts);  Joseph Anthony Cooley (Burlington, Massachusetts);  Jeremy Mineweaser (Marina Del Ray, California)
ABSTRACT In one aspect, a technique is provided for protecting a data set with a parity set defined by a bipartite graph having a degree distribution that includes no parity symbol having a degree less than three. In another aspect, a parity set defined by an irregular bipartite graph is transmitted along with the data set, and corruptions in the data set are decoded using the data set and the parity set. In another aspect, a particularly useful degree distribution for the parity symbols is defined.
FILED Tuesday, December 03, 2002
APPL NO 10/308627
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Error detection/correction and fault detection/recovery
714/800
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07028895 Ashaari
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Shahpour Ashaari (Gaithersburg, Maryland)
ABSTRACT A method to track a mailing. The method comprises: receiving mailing information from a mailer, the mailing information comprising shipment information relating to a shipment and a mailing code associated with a mailing, the shipment information comprising a shipment identifier; receiving a shipment at an induction facility, wherein the shipment comprises an encoded shipment and a mailing associated with the mailing code; scanning at least one of the encoded shipment identifier or the mailing code into a scanned code; matching the scanned code to the shipment identifier; notifying the mailer of the induction of the shipment; scanning at least one of the encoded shipment identifier or the mailing code at a delivery facility; and notifying the mailer of the delivery of the shipment.
FILED Thursday, July 31, 2003
APPL NO 10/631269
ART UNIT 2876 — Optics
CURRENT CPC
Registers
235/385
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07031959 Garner et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Michael C. Garner (Collierville, Tennessee);  Harry W. Aldstadt (Woodbridge, Virginia)
ABSTRACT A method and system for providing address matching. An address is compared against a plurality of address records in a database, wherein the database comprises at least one of the following: a delivery point database and an enhanced delivery point database. In addition, the method and system include providing an output data indicating whether the address has been matched to at least one of the plurality of address records in the database.
FILED Thursday, November 15, 2001
APPL NO 10/416857
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/3
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07030356 Pain et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Bedabrata Pain (Los Angeles, California);  Chao Sun (San Marino, California);  Guang Yang (West Covina, California);  Julie B. Heynssens (Santa Clarita, California)
ABSTRACT Systems and techniques to realize pointing and tracking applications with CMOS imaging devices. In general, in one implementation, the technique includes: sampling multiple rows and multiple columns of an active pixel sensor array into a memory array (e.g., an on-chip memory array), and reading out the multiple rows and multiple columns sampled in the memory array to provide image data with reduced motion artifact. Various operation modes may be provided, including TDS, CDS, CQS, a tracking mode to read out multiple windows, and/or a mode employing a sample-first-read-later readout scheme. The tracking mode can take advantage of a diagonal switch array. The diagonal switch array, the active pixel sensor array and the memory array can be integrated onto a single imager chip with a controller. This imager device can be part of a larger imaging system for both space-based applications and terrestrial applications.
FILED Monday, December 16, 2002
APPL NO 10/321300
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 07029646 Margrave et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
Non-Profit Organization (NPO)
Robert A. Welch Foundation
APPLICANT(S)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) John L. Margrave (Bellaire, Texas);  Zhenning Gu (Houston, Texas);  Robert H. Hauge (Houston, Texas);  Richard E. Smalley (Houston, Texas)
ABSTRACT A method for cutting single-wall carbon nanotubes involves partially fluorinating single-wall carbon nanotubes and pyrolyzing the partially fluorinated nanotubes in an inert atmosphere or vacuum up to about 1000° C. The nanotubes are optionally purified before cutting. The partial fluorination involves fluorinating the nanotubes to a carbon-fluorine stoichiometry of CFx, where x is up to about 0.3. The invention also relates to the derivatization of fluorinated and cut single-wall carbon nanotubes. The single-wall carbon nanotubes can be cut to any length depending on the fluorination and pyrolysis conditions. Short nanotubes are useful in various applications, such as field emitters for flat panel displays and as “seeds” for further nanotube growth.
FILED Tuesday, April 08, 2003
APPL NO 10/408886
ART UNIT 1754 — Optics
CURRENT CPC
Chemistry of inorganic compounds
423/447.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07029592 Frendt
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Joel M. Frendt (Boise, Idaho)
ABSTRACT A process for forming an etch mask having a discontinuous regular pattern utilizes beads, each of which has a substantially unetchable core covered by a removable spacer coating. Beads are dispensed as a hexagonally packed monolayer onto a thermo-adhesive layer. Following a vibrational step which facilitates hexagonal packing of the beads, the resultant assembly is heated so that the beads adhere to the adhesive layer. Excess beads are then discarded. Spacer shell material is then removed from each of the beads, leaving core etch masks. The core-masked target layer is then plasma etched to form a column of target material directly beneath each core. The cores and any spacer material underneath the cores are removed. The resulting circular island of target material may be used as an etch mask during wet isotropic etching of an underlying layer.
FILED Monday, August 11, 2003
APPL NO 10/639123
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Etching a substrate: Processes
216/42
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07030236 Jhaveri et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Mona Savitri Jhaveri (Rockville, Maryland);  Patrick Clay Elwood (Albany, Ohio);  Koong-Nah Chung (St. Louis, Missouri)
ABSTRACT The invention relates to treatment of cancers and cancerous cells which over-express α folate receptor (FRα) compared to the normal cells of the same tissue. The invention is directed to antisense oligonucleotides which are complimentary to the coding region of FRα, as well as the pharmaceutical compositions made thereof, and the methods of using the same for treatment of cancers, e.g. cancers of ovary, cervix, uterus, and brain.
FILED Monday, March 11, 2002
APPL NO 10/093523
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.500
VIEW PATENT @ USPTO:  Full Text   PDF 

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This week's information is published in the FedInvent Patents report for Tuesday, April 18, 2006.

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Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060418.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital