FedInvent™ Patents

Patent Details for Tuesday, May 09, 2006 

This page was updated on Sunday, March 26, 2023 at 08:02 PM GMT

Department of Defense (DOD) 

US 07040096 Manteiga et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) John A. Manteiga (North Andover, Massachusetts);  Walter J. Tingle (Danvers, Massachusetts);  Timothy A. White (Peabody, Massachusetts);  Kevin F. Canillas (Everett, Massachusetts)
ABSTRACT A method enables a gas turbine engine to be assembled. The method includes providing a combustor including a liner that defines a combustion chamber therein, and coupling a casing within the gas turbine engine to extend circumferentially around the combustor liner, wherein the casing includes an inlet and a scroll duct that is coupled in flow communication to the inlet and extends at least partially circumferentially around the liner. The method also includes coupling the inlet in flow communication with a feed air source.
FILED Monday, September 08, 2003
APPL NO 10/657312
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/722
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040158 Keith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) William L. Keith (Ashaway, Rhode Island);  Kimberly M. Cipolla (Portsmouth, Rhode Island)
ABSTRACT A method is presented for determining inner and outer boundary layer length scales from a succession of drag measurements of a cylindrical body in order to estimate flow noise and for computational modeling of the dynamics of towed arrays in a fluid medium. A succession of measurements of the total drag on a cylinder under tow at uniform known conditions (flow speed, fluid density, fluid viscosity, cylindrical body geometry) is taken. After each measurement, the cylinder is truncated by a fixed amount, and the process is repeated for the length of the cylinder. The measurements provide a spatially and temporally averaged measure of the mean wall shear stress and momentum thickness, from which the inner and outer length scales can be determined. The inner and outer boundary layer length scales may then be used for estimation of flow noise on towed cylindrical bodies and arrays.
FILED Monday, December 20, 2004
APPL NO 11/015805
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/170.330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040211 Bennett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Leon J. Bennett (Voorheesville, New York);  Donald G. Forkas (Rexford, New York);  George E. Hathaway, IV (Sprakers, New York);  Ronald G. Gast (Cohoes, New York);  Ronald S. Jacobs (Malta, New York)
ABSTRACT A mortar bomb retention apparatus for retaining a mortar bomb in a mortar tube includes a lever arm; a lever positioner in which the lever arm is rotatably mounted; a generally cylindrical housing having a central opening therethrough, the central opening comprising a large diameter portion and a small diameter portion, the lever positioner being fixed to the housing; a shoe disposed in the central opening in the housing; a compression spring disposed around the shoe in the large diameter portion of the central opening; and a shoe cap attached to an end of the shoe, one end of the compression spring bearing against the shoe cap, a portion of the lever arm contacting the shoe cap wherein rotation of the lever arm is operable to force the shoe downward.
FILED Wednesday, April 06, 2005
APPL NO 10/907574
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/1.350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040234 Maurer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Walter H. Maurer (Ridgecrest, California);  Gabriel H. Soto (Ridgecrest, California);  David R. Hollingsworth (Fallon, Nevada)
ABSTRACT The present invention relates to a device for electronically arming and firing a MEMS-scale interrupted explosive train to detonate a main charge explosive. The device includes a MEMS slider assembly housing a transfer charge electrically actuated to move between safe and armed positions of the explosive train.
FILED Thursday, July 22, 2004
APPL NO 10/901393
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/226
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040246 Doleski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert F. Doleski (Middletown, Rhode Island);  Stephen F. Oliver (Portsmouth, Rhode Island);  Stanley J. Olson (Newport, Rhode Island)
ABSTRACT In a submarine countermeasure vehicle and launch assembly the vehicle includes a forward end portion, an aft end portion provided with a propeller and fins, a hull portion extending between the forward and aft portions, the hull portion being circular in cross-section, and a thrust ring mounted on the fins and around the propeller, the thrust ring forming a convex configuration. The launch assembly includes a launch tube for retaining and launching the vehicle, a ram plate moveable in the launch tube to push the vehicle out an end of the launch tube, the ram plate having an engagement surface for contact with the thrust ring, the engagement surface being at least in part of a concave configuration. In a launch operation, the concave surface of the ram plate engages the convex configuration of the thrust ring.
FILED Monday, April 04, 2005
APPL NO 11/099779
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships
114/238
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040570 Sims et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) S. Richard F. Sims (Huntsville, Alabama);  William C. Pittman (Huntsville, Alabama)
ABSTRACT Applicants' ATR system is weather-agile because it is comprised of a primary target sensing means that is capable of surveilling the target scene in foul or fair weather, and a secondary target sensing means that is also capable of sensing targets in various weather. The primary and secondary sensing means communicate through a control center so that ultimately, among several weapons available, the most strategically located and equipped weapon is activated for the destruction of a selected target, given the weather. The control center accomplishes the communication by receiving the sensed target signature from the primary sensing means, processing the signature using database already resident in the center and transmitting the processed target signature to the weapon possessing the greatest potential for successfully destroying the target.
FILED Monday, September 29, 2003
APPL NO 10/675596
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeronautics and astronautics
244/3.160
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040577 Wood et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Jeffrey H. Wood (Eureka, Missouri);  Terry A. Sewell (Ballwin, Missouri);  Steven J. Miener (Florissant, Missouri)
ABSTRACT An apparatus and method for latching a canopy to a vehicle, such as an aircraft, that avoids plastic creep and crazing due to concentrated loads is provided. The apparatus includes first attachment components that are at least partially embedded within an injection-molded canopy and second attachment components that are connected to the canopy rail for attaching to the one or more first attachment components and thereby attaching the canopy to the canopy rail.
FILED Thursday, October 07, 2004
APPL NO 10/960144
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/129.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040805 Ou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Shichuan Ou (Beavercreek, Ohio);  Srinath V. Ekkad (Baton Rouge, Louisiana);  Richard B. Rivir (Bellbrook, Ohio)
ABSTRACT A method of infrared thermography is described. The invention utilizes a high resolution infrared thermography system and associated computer in conjunction with a test chamber to determine heat transfer coefficients and film effectiveness values from a single test.
FILED Monday, May 24, 2004
APPL NO 10/857373
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Thermal measuring and testing
374/43
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041250 Sherman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Powdermet, Inc. (Euclid, Ohio)
INVENTOR(S) Andrew J. Sherman (Granada Hills, California);  Asit Biswas (Studio City, California)
ABSTRACT A process for producing a binder phase free fine grained refractory metal compact at temperatures that are less than about 80 percent of the melting point of the refractory metal. A refractory metal is mixed with a metallic reagent to produce a mixture with a low melting point, and formed into a preform. The metallic reagent has limited solubility in the solid phase refractory metal. The refractory metal-metallic reagent mixture forms a liquid phase at the boundaries of the refractory metal grains. The metallic reagent diffuses into the boundaries of the refractory grains leaving a solid refractory-reagent phase at the boundaries between the grains. As heating continues at less than about 80 percent of the melting point of the refractory metal, consolidation takes place with minimum grain growth until the solid refractory-reagent phase substantially disappears and a refractory metal compact without a binder phase is recovered. If the refractory metal-metallic reagent preform is compacted to less than about 50 percent of theoretical density, it is possible to recover a microporous compact. At higher compaction rates substantially fully dense compacts are recovered. It is not necessary to apply pressure during the sintering phase.
FILED Thursday, August 22, 2002
APPL NO 10/227142
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Powder metallurgy processes
419/47
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041260 Hong et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) MesoSystems Technology, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Seung-Ho Hong (Richland, Washington);  Michael R. Powell (Kennewick, Washington);  Charles J. Call (Pasco, Washington)
ABSTRACT A fluid treatment system incorporating an integrated heat exchanger and thermal treatment unit. A fan draws or pushes a contaminated fluid through the heat exchanger, which is preferably of the counter flow type. The integrated heat exchanger and thermal treatment unit is fabricated by stacking sheets of metal foil so that gaps are defined between adjacent sheets. These gaps define alternating untreated and treated fluid channels. The untreated fluid flows through the heat exchanger and into the thermal treatment unit, with is disposed within aligned orifices formed in the metal foil sheets. Heat transfer occurs between adjacent treated and untreated channels, which greatly improves the efficiency with which a temperature of the untreated fluid entering the heat exchanger is changed as a result of heat transfer with the treated fluid that is exiting the heat exchanger. A header system is in fluid communication with either all of the treated or all of the untreated fluid channels. The integrated heat exchanger and thermal treatment unit also usable as a chemical reactor to generate a desired chemical product from at least one reactant.
FILED Monday, October 09, 2000
APPL NO 09/686917
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/198
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041495 Chodosh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Lewis A. Chodosh (West Chester, Pennsylvania);  Heather P. Gardner (Palo Alto, California)
ABSTRACT This invention relates generally to a novel CaM multi-functional protein kinase, which has been named Pregnancy Up-Regulated, Nonubiquitous CaM Kinase (PNCK), and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary development in a spatially heterogeneous manner in certain subsets of cells, and overexpressed in a subset of primary breast cancers. The invention further relates to an analysis of a correlation between carcinogenesis and postnatal development, particularly mammary development, especially associated with parity; as well as to methods of using the kinase, or gene encoding it, as markers, prognostic tools, screening tools and therapies, in vitro and in vivo that are based upon that correlation.
FILED Friday, December 21, 2001
APPL NO 10/032254
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041778 Curliss et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) David B. Curliss (Beavercreek, Ohio);  Jason E. Lincoln (Englewood, Ohio);  Katie E. Thorp (Tipp City, Ohio)
ABSTRACT A novel polyimide resin consisting essentially of 3,3′,4,4′-benzophenonetetracarboxylic dianhydride (BTDA), 3,4,3′,4′-biphenyltetracarboxylic dianhydride (BPDA), 2,2 bis (3′,4′-dicarboxy phenyl) hexafluoro propane dianhydride (6FDA), 2-(3,4-dicarboxyphenyl)-1-phenylacetylene anhydride (4-PEPA) and an aromatic diamine.
FILED Tuesday, May 18, 2004
APPL NO 10/849634
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
528/353
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041779 Dang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Thuy D. Dang (Centerville, Ohio);  Narayanan Venkatasubramanian (Beavercreek, Ohio);  Jar-Wha Lee (Columbus, Ohio);  Soo-Young Park (Daegu, South Korea);  Fred E. Arnold (Centerville, Ohio);  Barry L. Farmer (Xenia, Ohio)
ABSTRACT A benzobisazole polymer having repeating units of the formula:
wherein Q is
and wherein Z is —O—, —S— or —NH—. A new method for preparing 1,5-naphthalenedicarboxylic acid from 1,5-diaminonaphthalene under relatively mild conditions in good yields is also described.
FILED Monday, January 12, 2004
APPL NO 10/756888
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
528/423
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041987 Sharma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jagadish Sharma (Silver Spring, Maryland);  Joseph P. Teter (Mt. Airy, Maryland)
ABSTRACT A method of detecting a defect on a surface of a material due to exposure of the material to incident ionizing radiation, the method comprising the step of: inspecting a solid material having an atomically flat surface by at least an Atomic Force Microscope (AFM) or a Magnetic Force Microscope (MFM) for a defect in atomic structure on said surface due to exposure to ionizing radiation.
FILED Tuesday, February 25, 2003
APPL NO 10/372115
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/473.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042216 Barbic
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasedena, California)
INVENTOR(S) Mladen Barbic (San Gabriel, California)
ABSTRACT A method, apparatus, and article of manufacture provide the ability to conduct magnetic resonance tomographic microscopy. A two-dimensional non-crystalline sample is placed under the influence of a static polarizing first magnetic field. A radio-frequency field is then introduced perpendicular to the first magnetic field. To conduct the tomography, two or more magnetically resonant spins of the sample are simultaneously obtained by sequentially angularly rotating, around a prescribed axis, the sample with respect to a ferromagnetic sphere having a second magnetic field. The obtained spins are then used to reconstruct an image of the sample using computerized tomography.
FILED Thursday, May 20, 2004
APPL NO 10/849764
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/307
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042382 Paterno
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert M. Paterno (Richmond, Virginia)
ABSTRACT Multiple analog inputs are converted to respective multiple digital data records by analog to digital converters. A switch inserts a pseudorandom “alignment” code into each analog input at the beginning of conversion. After the analog to digital conversion, this pseudorandom code is detected by correlator filters to time align the plurality of digital data record with one another. The insertion of the pseudorandom code allows multiple analog inputs to be digitally converted in synchronization with one another. The disclosed logic controls its trigger timing and operation method.
FILED Thursday, May 19, 2005
APPL NO 11/134602
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/155
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042419 Werner et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Penn State Reserach Foundation (University Park, Pennsylvania)
INVENTOR(S) Douglas H. Werner (State College, Pennsylvania);  Pingjuan L. Werner (State College, Pennsylvania);  Michael J. Wilhelm (Stillwater, Oklahoma)
ABSTRACT An antenna system includes an antenna element and an electromagnetic bandgap element proximate the antenna element wherein the electromagnetic bandgap element is optimized for narrow bandwidth operation thereby providing radiofrequency selectivity to the antenna system. Preferably the electromagnetic bandgap element is tunable such as through use of a bias-alterable dielectric substrate or other tuning mechanism. The design approach also provides a means of creating an ultra-thin low-profile narrowband tunable channel selective antenna system suitable for low frequency applications.
FILED Friday, July 30, 2004
APPL NO 10/909213
ART UNIT 2821 — Semiconductors/Memory
CURRENT CPC
Communications: Radio wave antennas
343/909
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042549 Ren et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Hongwen Ren (Orlando, Florida);  Shin-Tson Wu (Oviedo, Florida)
ABSTRACT Using inhomogeneous sized liquid crystal (LC) droplets for lens and prisms. For forming a positive lens, the LC droplet size can gradually increase from the center to the side edges. For forming a negative lens, the LC droplet size can gradually decrease from the center to the side edges. The lens can be created by Ultra Violet light exposure to patterns. The lens can be tuned by applying voltage to the droplets. The inhomogeneous droplets can also be used in Fresnel lens and prisms. Applications of the invention can be used for eyeglasses, arrays, camera type zoom lenses and beam steering applications.
FILED Wednesday, December 31, 2003
APPL NO 10/750207
ART UNIT 2871 — Optics
CURRENT CPC
Liquid crystal cells, elements and systems
349/200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042570 Sailor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael J. Sailor (La Jolla, California);  Sonia Letant (Livermore, California)
ABSTRACT A method for analyzing gaseous or liquid samples is provided. Samples are interacted with pores of a porous thin film. A time-varying response of reflectivity is obtained from the surface of the porous thin film during the interaction. One or more analytes forming the sample or a part of the sample are identified based upon the time-varying response.
FILED Thursday, January 09, 2003
APPL NO 10/339163
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042631 Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Coherent Technologies, Inc. (Louisville, Colorado)
INVENTOR(S) Duane D. Smith (Louisville, Colorado);  Wayne S. Pelouch (McKinney, Texas);  Narasimha S. Prasad (Erie, Colorado);  Josef Unternährer (Lafayette, Colorado);  John Koroshetz (Broomfield, Colorado);  Iain McKinnie (Superior, Colorado)
ABSTRACT Power scalable, rectangular, multi-mode, self-imaging, waveguide technologies are used with various combination of large aperture configurations, 20, 50, 80, 322, 324, 326, 328, 330, 332, 334, 336, 338, Gaussian 360 and super-Gaussian 350 beam profiles, thermal management configurations 100, flared 240 and tapered 161 waveguide shapes, axial or zig-zag light propagation paths, diffractive wall couplers 304, 306, 308, 310, 312, 314, 316, 318, 320 and phase controller 200, flexibility 210, phased arrays 450, 490, beam combiners 530, 530′, and separators 344, 430, and other features to generate, transport, and deliver high power laser beams.
FILED Friday, April 05, 2002
APPL NO 10/117445
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optical: Systems and elements
359/333
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042646 Colandene
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Thomas M. Colandene (Springfield, Virginia)
ABSTRACT An infrared device in accordance with the present invention includes an optical train for receiving incident radiation into the device, a focal plane array for receiving the incident radiation from the optical train, and an optical power limiter (OPL) that is positioned therebetween. To improve the overall optical gain for the device, the optical train initially focuses the incident radiation into an intermediate focal plane that is located within the OPL. With this configuration, however, the incident radiation begins to lose focus once it passes through the intermediate focal plane and exits the OPL. To prevent this, the infrared device includes a plurality of microlenses on the OPL surface that is facing the focal plane array. The plurality of microlenses re-focuses the incident radiation onto a final focal plane that is coincident with the focal plane array.
FILED Monday, January 10, 2005
APPL NO 11/031000
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/626
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042649 Quake et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Stephen R. Quake (New York, New York);  Yann Gambin (Paris, France);  Oliver Legrand (Paris, France)
ABSTRACT Soft lithography with surface tension control is used to microfabricate extremely efficient solid immersion lenses (SILs) out of rubber elastomeric material for use in microscope type applications. In order to counteract the surface tension of the mold material in a negative mold that causes creep on a positive mold, material such as RTV is partially cured before use in order to allow the reticulation of polymer chains to change the viscosity of the uncured material in a controllable manner. In a specific embodiment, the techniques of soft lithography with surface tension control are used to make molded SILs out of the elastomer polydimethylsiloxane. The lenses achieve an NA in the range of 1.25. The principle of compound lens design is used to make the first compound solid immersion lens, which is corrected for higher light gathering ability and has a calculated NA=1.32. An important application of these lenses is integrated optics for microfluidic devices, specifically in a handheld rubber microscope for microfluidic flow cytometry.
FILED Tuesday, August 10, 2004
APPL NO 10/915943
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/661
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042696 Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) TASER International, Inc. (Scottsdale, Arizona)
INVENTOR(S) Patrick W. Smith (Paradise Valley, Arizona);  Magne H. Nerheim (Scottsdale, Arizona)
ABSTRACT An apparatus for immobilizing a target includes electrodes deployed after contact is made between the apparatus and the target. Spacing of deployed electrodes may be more accurate and/or more repeatable for more effective delivery of an immobilizing stimulus signal.
FILED Thursday, November 13, 2003
APPL NO 10/714572
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/232
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US 07042755 Bocian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (, None)
INVENTOR(S) David F. Bocian (Riverside, California);  Werner G. Kuhr (Riverside, California);  Jonathan Lindsey (Raleigh, North Carolina);  Peter Christian Clausen (Mohlin, Switzerland);  Daniel Tomasz Gryko (Warsaw, Poland)
ABSTRACT This invention provides novel high density memory devices (FIG. 3) that are electrically addressable permitting effective reading and writing, that provide a high memory density (102), that provide a high degree of fault tolerance, and that are amenable to efficient chemical synthesis and chip fabrication. The devices arc intrinsically latchable, defect tolerant, and support destructive or non-destructive read cycles. In a preferred embodiment, the device comprises a fixed electrode electrically coupled to a storage medium having a multiplicity of different and distinguishable oxidation states wherein data is stored in said oxidation states by the addition or withdrawal of one or more electrons from said storage medium via the electrically coupled electrode.
FILED Wednesday, June 28, 2000
APPL NO 10/019377
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/151
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042920 Belikov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Ruslan Belikov (Stanford, California);  Olav Solgaard (Stanford, California)
ABSTRACT A tunable laser comprises multiple reflectors defining a resonant cavity, and an optical gain medium positioned within the resonant cavity. One of the reflectors is a programmable micromirror array that acts as a tunable blazed diffraction grating providing continuous tuning of a single resonant mode over a wavelength gain region of the gain medium. The continuous tuning is provided by altering the micromirror array to shift, in synchrony, a resonant mode wavelength of the resonant cavity and a reflection filtering peak of the array. The array comprises a plurality of micromirror elements that can be controlled to independently move in a direction perpendicular to the plane of the array. In one embodiment, each element has a V-shaped movable mirror. In another embodiment, each element has a flat or slightly-tilted horizontal mirror and a vertical or nearly-vertical mirror orthogonal to the horizontal mirror producing a corner-cube-like reflection.
FILED Thursday, March 06, 2003
APPL NO 10/384180
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/92
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042930 Dafesh
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Philip A. Dafesh (Los Angeles, California)
ABSTRACT A multiple integration hypothesis C/A code acquisition system resolves bit boundaries using parallel correlators providing magnitude hypotheses during acquisition to reduce losses over the 20 ms integration period to improve the performance and sensitivity of C/A code receivers to achieve low C/No performance using inexpensive, imprecise oscillators and long noncoherent dwell periods, well suited for in-building, multipath, and foliage attenuated GPS signaling applicable to E911 communications with several dB of additional improvement in receiver sensitivity due to the ability to detect bit synchronization during acquisition.
FILED Thursday, June 06, 2002
APPL NO 10/165662
ART UNIT 2634 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/149
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043108 Olsen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Randall B. Olsen (Carlsbad, California)
ABSTRACT Photonic signals of high bandwidth are input into a planar spiral of waveguide. The spiral has a number of waveguide loops having a series optical tap areas wherein optical energy is leaked from the loops. The leaked optical energy is received by optical tap waveguides that carry the light for further processing.
FILED Friday, October 22, 2004
APPL NO 10/972104
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043343 Houlberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Christian L. Houlberg (Ventura, California);  Gary Glazner (Lancaster, California)
ABSTRACT A method for testing the performance of a Missile Time-Space-Position Information Unit. The method is utilized for Functional, Acceptance and Qualification test of the Missile Time-Space-Position Information Unit. The method has the capability of testing the Missile Time-Space-Position Information Unit to verify and document functionality of the Missile Time-Space-Position Information Unit prior to use of the Missile Time-Space-Position Information Unit in an operational environment.
FILED Wednesday, August 03, 2005
APPL NO 11/198411
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043369 Kolodner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Marc A. Kolodner (Gaithersburg, Maryland);  Patricia K. Murphy (Takoma Park, Maryland);  Edward E. Hume (Eldersburg, Maryland)
ABSTRACT A method and structure that inputs atmospheric forecast information from the atmospheric forecast database based on current, real time atmospheric measurements. The hyperspectral detection processing unit also inputs at least one selected reflectance library from the reflectance library database, and data collection and sensor parameters from the sensor. With this information, the hyperspectral detection processing unit employs a model to produce at least one mission radiance library during the mission planning phase. Then, during the actual mission execution, the sensor is used to collect the hyperspectral data and the comparator can immediately compare the hyperspectral data to the mission radiance library to identify features and/or targets.
FILED Wednesday, April 07, 2004
APPL NO 10/819621
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043420 Ratnaparkhi
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Adwait Ratnaparkhi (Monroe, New York)
ABSTRACT A system and method to facilitate natural language generation in a human-to-machine conversational system that produces written or spoken output. In one aspect, a user provides a scoring function and grammar rules including words and attributes. A method according to the present invention then generates possible reorderings of the words and attributes using the grammar rules and determines an optimal ordering of the words and attributes using the scoring function, which is then returned to the user.
FILED Monday, December 11, 2000
APPL NO 09/734154
ART UNIT 2654 — Audio Signals
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043437 Nielsen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Peter E. Nielsen (Gig Harbor, Washington);  Brook A. Thomson (Lakewood, Washington)
ABSTRACT Methods and systems which provide for standardized inpatient-outpatient nomenclatures and accepting both outpatient and inpatient data to commonly accessible storage. In a first method embodiment, the first method is characterized by accepting user input identifying at least two different names for a substantially similar grouping of one or more medical criteria; and accepting user input specifying at least one of the at least two different names as forming at least a part of an outpatient-inpatient standardized nomenclature for the substantially similar grouping of one or more medical criteria. In a second method embodiment, the second method is characterized by accepting either outpatient or inpatient data to commonly accessible storage. In one or more various embodiments, related systems include but are not limited to circuitry and/or programming for effecting the foregoing-referenced method embodiments; the circuitry and/or programming can be virtually any combination of hardware, software, and/or firmware configured to effect the foregoing-referenced method embodiments depending upon the design choices of the system designer.
FILED Thursday, January 03, 2002
APPL NO 10/038567
ART UNIT 2655 — Digital Audio Data Processing
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/270.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043475 Heer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Stamford, Connecticut)
INVENTOR(S) Jeffrey M. Heer (Berkeley, California);  Ed H. Chi (Palo Alto, California)
ABSTRACT Techniques for clustering user sessions using multi-modal information including proximal cue information are provided. The topology, content and usage of a document collection or web site are determined. User paths are then identified using longest repeating subsequence techniques. An information need feature vector is determined for each significant user path. Further, other feature vectors and proximal cue vectors for each document or web page in the significant path are determined. The other feature vectors include a content feature vector, a uniform resource locator feature vector, an inlink feature vector and an outlink feature vector, among others. The feature vectors and the proximal cue vectors are combined into a multi-modal vector that represents a user profile for each significant user path. The multi-modal vectors are clustered using a type of multi-modal clustering such as K-Means or Wavefront clustering.
FILED Thursday, December 19, 2002
APPL NO 10/248136
ART UNIT 2161 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043529 Simonoff
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Adam J. Simonoff (Fairfax Station, Virginia)
ABSTRACT A White Board system permitting a plurality of users to collaborate with one another irrespective of the respective user's hardware platform or operating system, includes a server computer, and a plurality of client computers coupled to the server computer. Preferably, each of the client computers logs into the server computer and is thereby assigned a unique identifier, each of the client computers includes a graphical user interface (GUI) which selectively displays any combination of objects having active content, active hyperlinks, and text, each of the client computers transmits user-generated objects to the server computer for selective retransmission to respective one of the client computers, the server selectively controls transmission of all user-generated objects to respective ones of the computers responsive to the respective assigned identifier, and the server commands one of the client computers to update a new client computer when the new client computer logs into the server. A method for operating a computer network to facilitate collaboration between users and software for implementing the method are also described.
FILED Monday, April 17, 2000
APPL NO 09/551364
ART UNIT 2145 — Graphical User Interface and Document Processing
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/205
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043535 Chi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Stamford, Connecticut)
INVENTOR(S) Ed H. Chi (Palo Alto, California);  Chris Olston (Los Altos, California)
ABSTRACT Techniques are provided for combining searching and browsing into a single interface. The topology and content of a document collection or web site is determined and user information need keywords are determined. Relevant documents are identified using search techniques and the relevant document paths determined. The relevant document paths are analyzed using information scent to generate information scent values for the relevant document paths. A display attribute of the associated connection or link is then synthesized based on the information scent, the keywords and the document. The process repeats for each new document or web page.
FILED Friday, March 30, 2001
APPL NO 09/821025
ART UNIT 2152 — Data Bases & File Management
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/218
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07040338 Unger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Marc A. Unger (South San Francisco, California);  Hou-Pu Chou (Pasadena, California);  Todd A. Thorsen (Pasadena, California);  Axel Scherer (Laguna Beach, California);  Stephen R. Quake (San Marino, California)
ABSTRACT A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.
FILED Wednesday, February 28, 2001
APPL NO 09/796871
ART UNIT 3754 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/15.190
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041234 Wellinghoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) Southwest Research Institute (San Antonio, Texas)
INVENTOR(S) Stephen T. Wellinghoff (San Antonio, Texas);  Douglas P. Hanson (San Antonio, Texas)
ABSTRACT A method for producing platform molecules comprising: forming a mixture comprising first and second phenylene rings comprising halogenated carboxylic groups, and a third phenylene ring comprising a desired substituent and a first functionality at a para-position to a second funcitonality; and exposing the mixture to conditions effective to react the first halogenated carboxylic group with the first functionality to produce a first ester bond, and the second halogenated carboxylic group with the second functionality to produce a second ester bond; producing platform molecules comprising terminal groups comprising the first functional group at a position para to first ester bond and the second functional group at a position para to the second ester bond.
FILED Wednesday, January 23, 2002
APPL NO 10/057548
ART UNIT 1756 — Printing/Measuring and Testing
CURRENT CPC
Compositions
252/299.670
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041276 Serbedzija et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Phylonix Pharmaceuticals, Inc. (Cambridge, Massachusetts)
INVENTOR(S) George N. Serbedzija (Woburn, Massachusetts);  Carlos Semino (Cambridge, Massachusetts);  Deanna Frost (Cambridge, Massachusetts)
ABSTRACT The present invention provides methods of screening an agent for activity using teleosts. Methods of screening an agent for angiogenesis activity, toxic activity and an effect cell death activity in teleosts are provided.
FILED Wednesday, September 05, 2001
APPL NO 09/947635
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041283 Achim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Cristian L. Achim (Allison Park, Pennsylvania);  Mihaela Avramut (Pittsburgh, Pennsylvania);  Adriana Zeevi (Pittsburgh, Pennsylvania)
ABSTRACT A method of treatment of neurodegenerative diseases using neuronal cell transplants is provided. The growth, survival and integration of the transplanted neuronal cells is enhanced by a method of culturing the neuronal cells with drugs having an affinity for immunophilins. Immunophilin binding drugs are optionally administered to the patient during transplantation and/or post-operatively. Neurotrophic factors can also be administered to the neuronal cells in vitro, or to the patient during the transplantation procedure and/or post-operatively.
FILED Monday, February 11, 2002
APPL NO 10/073522
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041294 Staats et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
Energy Frontier Research Centers (EFRC)
Photosynthetic Antenna Research Center (PARC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Herman F. Staats (Durham, North Carolina);  Barton F. Haynes (Durham, North Carolina);  Dhavalkumar D. Patel (Durham, North Carolina);  Gregory D. Sempowski (Durham, North Carolina)
ABSTRACT A method of eliciting an immune response against an antigen in a vertebrate subject, the method comprising the steps of providing an antigen-adjuvant composition comprising the antigen and a substantially non-toxic adjuvant molecule having biological activity in mucosal tissues, and administering said antigen-adjuvant composition to the vertebrate subject in a manner such that initial contact occurs in mucosal tissue of the vertebrate subject, whereby an immune response is elicited. Cytokines are preferred adjuvants. Preferred cytokines are interleukin-1α(IL-1α) and interleukin-1β (IL-1β).
FILED Tuesday, June 05, 2001
APPL NO 09/874103
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041296 Stober et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Warren Stober (Bethesda, Maryland);  Ivan J. Fuss (Bethesda, Maryland);  Brian L. Kelsall (Washington, District of Columbia);  Monica Boirivant (Rome, Italy)
ABSTRACT The present invention provides a method of treating or preventing inflammation in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. The present invention also provides a method of decreasing the activity of interferon gamma in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. Further provided is a method of decreasing the activity of IL-12 in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. Additionally, the present invention provides a method of treating or preventing a Th1 T-cell mediated autoimmune disorder in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B.
FILED Thursday, November 09, 2000
APPL NO 10/129907
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041437 Ruvkun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Gary Ruvkun (Newton, Massachusetts);  Scott Ogg (Newton, Massachusetts)
ABSTRACT Disclosed herein are novel genes and methods for the screening of therapeutics useful for treating impaired glucose tolerance conditions, as well as diagnostics and therapeutic compositions for identifying or treating such conditions.
FILED Tuesday, September 25, 2001
APPL NO 09/963693
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041441 Steven et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Alasdair C. Steven (Silver Spring, Maryland);  Paul T. Wingfield (Bethesda, Maryland);  Lindsay W. Black (Baltimore, Maryland);  Zhaojun Ren (Elkridge, Maryland)
ABSTRACT Disclosed is a phage display system in which the molecules to be displayed (i.e., molecules of interest) are bound to dispensable capsid polypeptides such as SOC (small outer capsid) and HOC (highly antigenic outer capsid) polypeptides that are, in turn, bound to a surface lattice protein, such as those on the surface of a virion or polyhead. Also disclosed are methods of displaying a molecule of interest, methods of immunizing a patient by administering a displayed antigen, and methods of treating a patient who has a disorder associated with aberrent expression or activity of a biological molecule. In the latter instance, the method includes administering a displayed polypeptide, such as an immunoglobulin molecule or an enzyme, that is capable of specifically interacting with the aberrent biological molecule.
FILED Friday, April 11, 1997
APPL NO 08/837301
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041447 Evans et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) St. Jude Children's Hospital, Inc. (Memphis, Tennessee)
INVENTOR(S) William Edward Evans (Cordova, Tennessee);  Oliver Gene McDonald (Charlottesville, Virginia)
ABSTRACT The invention relates to methods for detecting genetic polymorphisms in an organism, particularly to the detection of genetic polymorphisms that are due to multiple distal nucleotide polymorphisms within a gene. Methods are provided for determining the haplotype structure of a gene, or other contiguous DNA segment, having two or more nucleotide polymorphisms that are separated by kilobases of DNA. The methods involve the use of PCR amplification and DNA ligation to bring the nucleotide polymorphisms on a particular allele of the gene into close proximity to facilitate the determination of haplotype structure.
FILED Monday, April 09, 2001
APPL NO 09/829113
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041449 Prolla et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Tomas A. Prolla (Madison, Wisconsin);  Richard H. Weindruch (Madison, Wisconsin);  Cheol-Koo Lee (Madison, Wisconsin);  Tsuyoshi Kayo (Madison, Wisconsin)
ABSTRACT A method of measuring the biological age of a multicellular organism is disclosed. In one embodiment, the method comprises the steps of: (a) obtaining a sample of nucleic acid isolated from the organism's organ, tissue or cell, wherein the nucleic acid is RNA or a cDNA copy of RNA and (b) determining the gene expression pattern of at least one of the genes selected from the group consisting of M21050, Z49204, U49430, K02782, X58861, X66295, M22531, X67809, U19118, M64086, M63695, U39066, X92590, X56518, AA182189, X16493, U20344, X16834, X82648, D00754, D16313, L38971 and X15789.
FILED Friday, March 15, 2002
APPL NO 10/098205
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041455 Magness et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Illumigen Biosciences, Inc. (Seattle, Washington)
INVENTOR(S) Charles Lee Magness (Seattle, Washington);  Dake Sun (Redmond, Washington)
ABSTRACT This invention provides methods for identifying mutations and methylation patterns in diploid DNA sequence signal data. In particular, the invention provides methods for (1) obtaining two parental allele sequences from diploid DNA sequence signal data, (2) identifying the mutation and haplotype patterns in the two parental allele sequences, (3) assigning likelihood scores for the mutations thus identified, and (4) identifying patterns of methylation.
FILED Friday, March 07, 2003
APPL NO 10/383922
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041465 Hultgren et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Scott J. Hultgren (St. Louis, Missouri);  Frederic G. Sauer (St. Louis, Missouri);  Gabriel Waksman (St. Louis, Missouri);  Klaus Fuetterer (St. Louis, Missouri);  Devapriya Choudhury (Uppsala, Sweden);  Stefan D. Knight (Uppsala, Sweden);  Michelle Barnhart (St. Louis, Missouri)
ABSTRACT Many Gram-negative pathogens assemble adhesive pili structures on their surfaces that allow them to colonize host tissues and cause disease. The present invention relates to novel compounds that mimic a chaperone G1 beta-strand or an amino terminal motif of a pilus subunit. The present invention also relates to the complex formed from the binding of such mimic compounds to the hydrophobic groove of a pilus subunit. Competitively interacting with the binding site of pili subunits will negatively affect the chaperone/usher pathway, which is one molecular mechanism by which Gram-negative bacteria assemble adhesive pili structures, and thus prevent or inhibit pilus assembly.
FILED Friday, August 11, 2000
APPL NO 09/637216
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041466 Kaltenboeck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) Auburn University (Auburn, Alabama)
INVENTOR(S) Bernhard Kaltenboeck (Auburn, Alabama);  Jin Huang (Chestnut Hill, Massachusetts)
ABSTRACT Compositions and methods are provided for evaluating the progress of disease induced by infection with Chlamydia spp. Specifically, the invention provides a mouse lung disease model of infection with Chlamydia spp. bacteria. The compositions and methods of the invention find use in evaluating the efficacy of vaccines and other therapeutic or prophylactic treatments of Chlamydia-induced disease.
FILED Friday, August 01, 2003
APPL NO 10/632426
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.320
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US 07041475 Malouf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Nadia Malouf (Durham, North Carolina);  Timothy C. Nichols (Chapel Hill, North Carolina)
ABSTRACT Isolated and purified platelet voltage dependent calcium channel (VDCC) α1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC α1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC α1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.
FILED Thursday, December 20, 2001
APPL NO 10/029413
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
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US 07041489 Wertz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S) Gail W. Wertz (Birmingham, Alabama);  Alexander George Megaw (Glasgow, United Kingdom);  A. Tom Oomens (Birmingham, Alabama)
ABSTRACT The present invention provides recombinant respiratory syncytial viruses (RSV) in which all of the surface glycoprotein genes encoding the attachment protein G, the fusion protein F, and the Small Hydrophobic protein SH are deleted. The genes are replaced by a chimeric gene encoding a heterologous entry protein derived from the Vesicular Stomatitis Virus G protein or GP64 of baculovirus. Alternatively, the replacement proteins are provided in trans. Marker genes such as those encoding β-glucuronidase (GUS) and green fluorescent protein (EGFP) are also added to the upstream and downstream side of the hybrid gene for easy detection. These infectious recombinant respiratory syncytial viruses offer alternatives and improvements as vaccine candidates.
FILED Tuesday, October 01, 2002
APPL NO 10/262238
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/235.100
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US 07041491 Inohara et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Naohiro Inohara (Ann Arbor, Michigan);  Gabriel Nuñez (Ann Arbor, Michigan)
ABSTRACT The present invention relates to the NOD proteins and nucleic acids encoding the NOD proteins. The present invention further provides assays for the detection of NOD polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NOD proteins.
FILED Friday, March 05, 2004
APPL NO 10/794342
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/253.300
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US 07041495 Chodosh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Lewis A. Chodosh (West Chester, Pennsylvania);  Heather P. Gardner (Palo Alto, California)
ABSTRACT This invention relates generally to a novel CaM multi-functional protein kinase, which has been named Pregnancy Up-Regulated, Nonubiquitous CaM Kinase (PNCK), and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary development in a spatially heterogeneous manner in certain subsets of cells, and overexpressed in a subset of primary breast cancers. The invention further relates to an analysis of a correlation between carcinogenesis and postnatal development, particularly mammary development, especially associated with parity; as well as to methods of using the kinase, or gene encoding it, as markers, prognostic tools, screening tools and therapies, in vitro and in vivo that are based upon that correlation.
FILED Friday, December 21, 2001
APPL NO 10/032254
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
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US 07041503 Nye et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  Alexion Pharmaceuticals, Inc. (Cheshire, Connecticut)
INVENTOR(S) Steven H. Nye (Mequon, Wisconsin);  Michael J. Lenardo (Potomac, Maryland);  Henry F. McFarland (Gaithersburg, Maryland);  Louis A. Matis (Southport, Connecticut);  Eileen Elliott Mueller (East Haven, Connecticut);  John P. Mueller (East Haven, Connecticut);  Clara M. Pelfrey (Gaithersburg, Maryland);  Stephen P. Squinto (Bethany, Connecticut);  James A. Wilkins (Woodbridge, Connecticut)
ABSTRACT Compositions and methods are provided for the clinical assessment, diagnosis, and treatment of multiple sclerosis. The compositions of the invention are molecules related to the 21.5 kDa fetal isoform of human myelin basic protein, and include nucleic acids and polypeptides. The nucleic acid molecules of the invention are useful in the efficient production of modified and unmodified 21.5 kDa myelin basic protein polypeptides, such polypeptides being useful for assaying T cells for responsiveness to myelin basic protein epitopes. The polypeptides of the invention are also useful as therapeutic agents that act by inducing T cell responses, including apoptosis, as a means of treating multiple sclerosis.
FILED Tuesday, May 02, 1995
APPL NO 08/431644
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
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US 07041634 Weber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Bristol Myers-Squibb Company (New York, New York)
INVENTOR(S) Collin J. Weber (Atlanta, Georgia);  Mary K. Hagler (Loganville, Georgia);  Peter S. Linsley (Seattle, Washington);  Judith A. Kapp (Atlanta, Georgia);  Susan A. Safley (Decatur, Georgia)
ABSTRACT This invention provides a method of inhibiting viable cells transplanted into a subject from being destroyed by the subject's immune system which comprises: a) containing the viable cells, or tissue comprising the viable cells, prior to transplantation within a device comprising a semipermeable membrane; and b) treating the subject with a substance which inhibits an immune-system costimulation event in an amount effective to inhibit the subject's immune system from responding to said contained cells or tissue. In one embodiment, the substance which inhibits an immune-system costimulation event is CTLA4. Also provided by this invention is a method of treating diabetes in a subject which comprises: a) containing viable insulin-producing cells, or tissue comprising such cells, within a device comprising a semipermeable membrane; b) transplanting an effective amount of such contained viable insulin-producing cells into the subject; and c) treating the subject with an effective amount of a substance which inhibits an immune-system costimulation event.
FILED Friday, March 27, 1998
APPL NO 09/049865
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 07041638 Floros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Joanna Floros (Hershey, Pennsylvania);  David S. Phelps (Hershey, Pennsylvania);  Colin MacNeill (Hershey, Pennsylvania);  Todd M. Umstead (Etters, Pennsylvania);  Zhenwu Lin (Hershey, Pennsylvania);  Judith Weisz (Bainbridge, Pennsylvania)
ABSTRACT A means and method for treating pulmonary fibrosis and vaginitis in animals is described. The compositions include surfactant lipids in a pharmaceutically acceptable carrier. Surfactant lipids have been found to suppress the synergistic effect of bleomycin and SP-A in enhancing proinflammatory cytokine production. Surfactant lipids are also effective in the prevention and treatment of pulmonary fibrosis resulting from exposure to inflammatory agents affecting cytokine production. Furthermore, surfactant lipids are effective in treating attenuating the effect of proinflammatory cytokine production in vaginitis.
FILED Friday, May 02, 2003
APPL NO 10/428598
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/8
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041783 Reed et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Burnham Institute (La Jolla, California)
INVENTOR(S) John C. Reed (Rancho Santa Fe, California);  Kazuya Okada (Isahaya, Japan)
ABSTRACT In accordance with the present invention, there are provided novel Survivin-binding-proteins (SBPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SBPs can be employed in a variety of ways, for example, for the production of anti-SBP antibodies thereto, in therapeutic compositions and in bioassays methods employing such proteins and/or antibodies. Also provided are transgenic non-human mammals that express the invention protein.
FILED Thursday, January 24, 2002
APPL NO 10/057813
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041784 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Xiaodong Wang (Dallas, Texas);  Chunying Du (Dallas, Texas)
ABSTRACT The invention provides methods and compositions for enhancing apoptosis of pathogenic cells. The general method comprises the of contacting the cells with an effective amount of an AV peptoid, wherein the AV peptoid is a peptide comprising AX1, wherein X1 is V, I or L, or a peptide mimetic thereof, which interacts with an Inhibitor of Apoptosis protein (IAP) as measured by IAP binding, procaspase-3 activation or promotion of apoptosis, wherein apoptosis of the pathogenic cells is enhanced. The subject compositions encompass pharmaceutical compositions comprising a therapeutically effective amount of a subject AV peptoid in dosage form and a pharmaceutically acceptable carrier, wherein the AV peptoid is a peptide comprising AX1, wherein X1 is V, I or L, or a peptide mimetic thereof, which inhibits the activity of an Inhibitor of Apoptosis protein (IAP) as measured by IAP binding, procaspase-3 activation or promotion of apoptosis. The invention also provides assays for identifying agents which modulates the interaction of an AV peptoid with an IAP, active compounds identified in such screens and their use in the foregoing compositions and therapeutic methods.
FILED Friday, August 15, 2003
APPL NO 10/641539
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
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US 07041801 Quertermous et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Vanderbilt University (, None);  Valentis, Inc. (, None)
INVENTOR(S) Thomas Quertermous (Nashville, Tennessee);  Brigid Hogan (Brentwood, Tennessee);  H. Ralph Snodgrass (Powell, Ohio);  Thomas Joel Zupancic (Worthington, Ohio)
ABSTRACT The present invention relates to a member of a novel gene family referred to as developmentally-regulated endothelial cell locus-1 (del-1). In particularly, the invention related to del-1 nucleotide sequences, Del-1 amino acid sequences, methods of expressing a functional gene product, and methods of using the gene and gene product. Since del-1 is expressed in endothelial cells and certain cancer cells, it may be useful as an endothelial cell and tumor marker. In addition, anti-Del-1 antibodies for immunological assessment of Del-1 protein expression as well as for inhibiting or stimulating Del-1 function are provided.
FILED Monday, January 25, 1999
APPL NO 09/237981
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041806 Tessier-Lavigne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Mark Tessier-Lavigne (San Francisco, California);  E. David Leonardo (San Francisco, California);  Lindsay Hinck (San Francisco, California);  Masayuki Masu (San Francisco, California);  Kazuko Keino-Masu (San Francisco, California)
ABSTRACT The invention provides methods and compositions relating to vertebrate UNC-5 proteins which function as receptor proteins for netrins, a family of cell guidance proteins. The proteins may be produced recombinantly from transformed host cells from the disclosed vertebrate UNC-5 encoding nucleic acid or purified from human cells. The invention provides specific hybridization probes and primers capable of specifically hybridizing with the disclosed vertebrate unc-5 gene, vertebrate UNC-5-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
FILED Friday, September 27, 2002
APPL NO 10/256702
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041810 Small et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University Of Cincinnati (Cincinnati, Ohio)
INVENTOR(S) Kersten M. Small (Cincinnati, Ohio);  Stephen B. Liggett (Cincinnati, Ohio)
ABSTRACT The present invention includes polymorphisms in nucleic acids encoding the alpha-2B, alpha-2A, and alpha-2C adrenergic receptor and expressed alpha-2B, alpha-2A and alpha-2C adrenergic receptor molecule. The invention also pertains to methods and molecules for detecting such polymorphisms. The invention further pertains to the use of such molecules and methods in the diagnosis, prognosis, and treatment of diseases such as cardiovascular and central nervous system disease.
FILED Thursday, November 01, 2001
APPL NO 10/001073
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041819 Sessler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Jonathan L. Sessler (Austin, Texas);  Manuel Marquez (Lincolnshire, Illinois);  Pavel Anzenbacher, Jr. (Bowling Green, Ohio);  James A. Shriver (Austin, Texas)
ABSTRACT The present invention provides halogenated calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles having 4–12 pyrrolic rings with greater stability, enhanced anion and neutral molecule binding affinity, and different binding selectivites as compared to their non-halogenated congeners as judged from 1H NMR, 19F NMR and fluorescence emission spectroscopic analyses.
FILED Friday, August 24, 2001
APPL NO 09/939514
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
540/145
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US 07041821 Tsien et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roger Y. Tsien (La Jolla, California);  Christina Hauser (San Diego, California)
ABSTRACT The invention provides Zn-chelating compounds that are molecularly engineered to bind to a specific target sequence in a protein of interest. The Zn2+ ion is far less toxic and promiscuous than nickel and therefore provides an attractive alternative to Ni-based labeling systems. Invention Zn-chelating compounds also do not require oxidizable thiols and therefore can be used in non-reducing environments such as the surface of living cells. In addition, the target sequence is genetically encodable and requires incorporation of only a few amino acids, unlike fusions to fluorescent proteins such as GFP.
FILED Friday, January 16, 2004
APPL NO 10/759762
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
544/104
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US 07041839 Hanson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Robert N. Hanson (Newtown, Massachusetts);  Carolyn Friel (Boston, Massachusetts);  Choon Young Lee (Boston, Massachusetts)
ABSTRACT The present invention comprises the design, synthesis and development of a new class of chemotherapeutic agents for prophylactic and therapeutic treatments in a mammal, particularly a human, believed to be at risk of suffering from a hormone-responsive disorde. In an embodiment of the invention, such treatments include therapeutic compositions comprising novel steroidal antiestrogen and antiandrogen compounds. In a preferred embodiment, such a novel compound of the present invention has an address and a message component, which are made into a single composite entity for more aggressive intervention and effective treatment of hormone-responsive disorders, thereby prolonging the disease-free interval for the patient and reducing a number of side effects.
FILED Friday, June 22, 2001
APPL NO 10/297310
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Organic compounds
552/618
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US 07041851 Kung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Hank F. Kung (Wynnewood, Pennsylvania);  Chyng-Yann Shiue (Villanova, Pennsylvania);  Shunichi Oya (Princeton Junction, New Jersey);  Seok Rye Choi (Drexel Hill, Pennsylvania);  Grace G. Shiue (Villanova, Pennsylvania);  Ping Fang (Drexel Hill, Pennsylvania)
ABSTRACT This invention relates to novel fluorinated phenyl thiphenyl (also named diarylsulfide) derivatives and their use in Positron Emission Tomagraphy (PET) imaging of Serotonin Transporters (SERTS). The present invention also provides diagnostic compositions comprising the novel compounds of the present invention, and a pharmaceutically acceptable carrier or diluent. The invention further provides a method of imaging SERTS, comprising introducing into a patient a detectable quantity of a labeled compound of the present invetion, or a pharmaceutically acceptable salt, ester, amide or prodrug thereof.
FILED Friday, March 14, 2003
APPL NO 10/388363
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
564/341
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US 07041859 Kabalka
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) George W. Kabalka (Knoxville, Tennessee)
ABSTRACT A method for obtaining a halogenated organic compound, whereby an organotrifluoroborate compound is reacted with a halide ion in the presence of an oxidizing agent to produce the corresponding halogenated organic compound. The method may be used for producing radiohalogenated organic compounds.
FILED Tuesday, July 05, 2005
APPL NO 11/174797
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
570/260
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US 07042214 Cunningham et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Charles H. Cunningham (San Francisco, California);  John M. Pauly (Redwood City, California);  Daniel B. Vigneron (Corte Madera, California)
ABSTRACT A method for designing non-linear phase 180° spectral-spatial radio frequency pulses that can be used for spectral editing in magnetic resonance spectroscopic imaging. A novel feature of the pulse is a symmetric sweep developed by the spectral profile from the outside edges of the spectral window towards the middle whereby coupled components are tipped simultaneously and over a short interval. Pulses have been designed for lactate editing at 1.5T and 3T. The spectral and spatial spin-echo profiles of the RF pulses can be measured experimentally and altered in an iterative manner. Spectral-spatial radio frequency (SSRF) pulses allow simultaneous selection in both frequency and spatial domains. These pulses are particularly important for clinical and research magnetic resonance spectroscopy (MRS) applications for suppression of large water and lipid resonances.
FILED Tuesday, April 13, 2004
APPL NO 10/823979
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/307
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US 07042221 Carney et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) Syracuse University (Syracuse, New York)
INVENTOR(S) Laurel H. Carney (Syracuse, New York);  Michael C. Anzalone (Syracuse, New York)
ABSTRACT A system for the detection of narrowband signals in wideband noise that combines information across two frequency channels that straddle the frequency of the target signal. Two band pass filters having center frequencies that straddle the frequency of the target signal and that have phase transfer functions that differ by 180 degrees relative to each other at the frequency of the target signal. The presence of the target signal is detected by performing a running cross-correlation of the outputs of saturating, non-linearities that follow from the filters, and determining when the output of the running cross-correlator drops below a predetermined threshold due to the phase shift between the two filter responses caused by the presence of the target signal.
FILED Thursday, July 31, 2003
APPL NO 10/631131
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/314
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US 07043066 Doi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) Arch Development Corporation (Chicago, Illinois)
INVENTOR(S) Kunio Doi (Willowbrook, Illinois);  Qiang Li (Clarendon Hills, Illinois);  Shigehiko Katsuragawa (Morioka, Japan);  Takayuki Ishida (Hiroshima, Japan)
ABSTRACT A method, system and computer readable medium for computerized processing of chest images including obtaining a digital first image of a chest (S100); producing a second image which is a mirror image (S300) of the first image; performing image warping on one of the first and second images to produce a warped image (S400) which is registered to the other of the first and second images; and subtracting the warped image from the other image to generate a subtraction image (S600). Another embodiment includes obtaining a digital first image of the chest of a subject; detecting ribcage edges on both sides of the lungs in the first chest image; determining average horizontal locations of the left and right ribcage edges at plural vertical locations; fitting the determined average horizontal locations to a straight line to derive a midline; rotating the chest image so that the midline is vertical; and shifting the rotated image to produce a lateral inclination corrected (S200) second image with the midline centered in the lateral inclination corrected image.
FILED Friday, November 05, 1999
APPL NO 09/830562
ART UNIT 2623 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/132
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US 07043500 Leary
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas Syxtem (Austin, Texas)
INVENTOR(S) James F. Leary (Galveston, Texas)
ABSTRACT A data analysis system and/or method, e.g., a data mining/data exploration method, using subtractive clustering is used to explore the similarities and differences between two or more multi-dimensional data sets, e.g., generated using a flow cytometer, an image analysis system, gene expression, or protein microarrays.
FILED Thursday, April 25, 2002
APPL NO 10/132090
ART UNIT 2163 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/104.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07040003 Hall et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) IntelliServ, Inc. (Provo, Utah)
INVENTOR(S) David R. Hall (Provo, Utah);  H. Tracy Hall, Jr. (Provo, Utah);  David S. Pixton (Lehi, Utah);  Scott Dahlgren (Provo, Utah);  Michael A. Briscoe (Lehi, Utah);  Cameron Sneddon (Provo, Utah);  Joe Fox (Spanish Fork, Utah)
ABSTRACT The present invention includes a method of making an inductive coupler for downhole components. The method includes providing an annular housing, preferably made of steel, the housing having a recess. A conductor, preferably an insulated wire, is also provided along with a plurality of generally U-shaped magnetically conducting, electrically insulating (MCEI) segments. Preferably, the MCEI segments comprise ferrite. An assembly is formed by placing the plurality of MCEI segments within the recess in the annular housing. The segments are aligned to form a generally circular trough. A first portion of the conductor is placed within the circular trough. This assembly is consolidated with a meltable polymer which fills spaces between the segments, annular housing and the first portion of the conductor. The invention also includes an inductive coupler including an annular housing having a recess defined by a bottom portion and two opposing side wall portions. At least one side wall portion includes a lip extending toward but not reaching the other side wall portion. A plurality of generally U-shaped MCEI segments, preferably comprised of ferrite, are disposed in the recess and aligned so as to form a circular trough. The coupler further includes a conductor disposed within the circular trough and a polymer filling spaces between the segments, the annular housing and the conductor.
FILED Saturday, March 27, 2004
APPL NO 10/708845
ART UNIT 2832 — SELECT * FROM codes_techcenter;
CURRENT CPC
Metal working
029/602.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040094 Fischer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Larry E. Fischer (Los Gatos, California);  Brian L. Anderson (Lodi, California);  Kevin C. O'Brien (San Ramon, California)
ABSTRACT A combustion engine method and system provides increased fuel efficiency and reduces polluting exhaust emissions by burning fuel in a two-stage combustion system. Fuel is combusted in a piston engine in a first stage producing piston engine exhaust gases. Fuel contained in the piston engine exhaust gases is combusted in a second stage turbine engine. Turbine engine exhaust gases are used to supercharge the piston engine.
FILED Tuesday, September 09, 2003
APPL NO 10/657900
ART UNIT 3748 — SELECT * FROM codes_techcenter;
CURRENT CPC
Power plants
060/606
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041294 Staats et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
Energy Frontier Research Centers (EFRC)
Photosynthetic Antenna Research Center (PARC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Herman F. Staats (Durham, North Carolina);  Barton F. Haynes (Durham, North Carolina);  Dhavalkumar D. Patel (Durham, North Carolina);  Gregory D. Sempowski (Durham, North Carolina)
ABSTRACT A method of eliciting an immune response against an antigen in a vertebrate subject, the method comprising the steps of providing an antigen-adjuvant composition comprising the antigen and a substantially non-toxic adjuvant molecule having biological activity in mucosal tissues, and administering said antigen-adjuvant composition to the vertebrate subject in a manner such that initial contact occurs in mucosal tissue of the vertebrate subject, whereby an immune response is elicited. Cytokines are preferred adjuvants. Preferred cytokines are interleukin-1α(IL-1α) and interleukin-1β (IL-1β).
FILED Tuesday, June 05, 2001
APPL NO 09/874103
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041414 Thackeray et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Michael M. Thackeray (Naperville, Illinois);  John T. Vaughey (Elmhurst, Illinois);  Dennis W. Dees (Downers Grove, Illinois)
ABSTRACT This invention relates to electrodes for non-aqueous lithium cells and batteries with silver manganese oxide positive electrodes, denoted AgxMnOy, in which x and y are such that the manganese ions in the charged or partially charged electrodes cells have an average oxidation state greater than 3.5. The silver manganese oxide electrodes optionally contain silver powder and/or silver foil to assist in current collection at the electrodes and to improve the power capability of the cells or batteries. The invention relates also to a method for preparing AgxMnOy electrodes by decomposition of a permanganate salt, such as AgMnO4, or by the decomposition of KMnO4 or LiMnO4 in the presence of a silver salt.
FILED Tuesday, January 07, 2003
APPL NO 10/338175
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/219
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041481 Anderson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Brian L. Anderson (Lodi, California);  Billy W. Colston, Jr. (San Ramon, California);  Chris Elkin (San Ramon, California)
ABSTRACT A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample.
FILED Friday, March 14, 2003
APPL NO 10/389130
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041616 Nenoff et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Tina M. Nenoff (Albuquerque, New Mexico);  Steven G. Thoma (Albuquerque, New Mexico);  Mutlu Kartin (Albuquerque, New Mexico)
ABSTRACT A method for carbonizing a zeolite comprises depositing a carbon coating on the zeolite pores by flowing an inert carrier gas stream containing isoprene through a regenerated zeolite at elevated temperature. The carbonized zeolite is useful for the separation of light hydrocarbon mixtures due to size exclusion and the differential adsorption properties of the carbonized zeolite.
FILED Monday, April 14, 2003
APPL NO 10/414184
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/85
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041859 Kabalka
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) George W. Kabalka (Knoxville, Tennessee)
ABSTRACT A method for obtaining a halogenated organic compound, whereby an organotrifluoroborate compound is reacted with a halide ion in the presence of an oxidizing agent to produce the corresponding halogenated organic compound. The method may be used for producing radiohalogenated organic compounds.
FILED Tuesday, July 05, 2005
APPL NO 11/174797
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
570/260
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041908 Hall et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) IntelliServ, Inc. (Provo, Utah)
INVENTOR(S) David R. Hall (Provo, Utah);  Tracy H. Hall, Jr. (Provo, Utah);  David S. Pixton (Lehi, Utah);  Scott Steven Dahlgren (Alpine, Utah);  Joe Fox (Spanish Fork, Utah);  Cameron Sneddon (Lombard, Illinois);  Michael A. Briscoe (Lehi, Utah)
ABSTRACT The invention is a system for transmitting data through a string of downhole components. In accordance with one aspect of the invention, the system includes a plurality of downhole components, such as sections of pipe in a drill string. Each component has a first and second end, with a first communication element located at the first end and a second communication element located at the second end. Each communication element includes a first contact and a second contact. The system also includes a coaxial cable running between the first and second communication elements, the coaxial cable having a conductive tube and a conductive core within it. The system also includes a first and second connector for connecting the first and second communication elements respectively to the coaxial cable. Each connector includes a conductive sleeve, lying concentrically within the conductive tube, which fits around and makes electrical contact with the conductive core. The conductive sleeve is electrically isolated from the conductive tube. The conductive sleeve of the first connector is in electrical contact with the first contact of the first communication element, the conductive sleeve of the second connector is in electrical contact with the first contact of the second communication element, and the conductive tube is in electrical contact with both the second contact of the first communication element and the second contact of the second communication element.
FILED Tuesday, November 23, 2004
APPL NO 10/904688
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Conductors and insulators
174/75.C00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041910 Swager et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Steffen Zahn (Pennsburg, Pennsylvania)
ABSTRACT The present invention generally relates to stable emissive aggregates of polymers. The aggregates are composed of various polymer molecules arranged in such a way as to allow extended electronic couplings between nearby polymer molecules, enhancing exciton transport, while minimizing the effects of quenching due to interchain interactions. For example, the polymer molecules may be arranged in a non-aligned, electronically-communicative manner (for example, at an oblique angle), stabilized by various methods such as chemical linkages or physical interactions. Within the aggregate, electronic interactions along the polymer molecule may extend to nearby polymer molecules, which may be observed as a shift in the absorption spectra relative to a random dispersion. Light emitted from the aggregate may be polarized in some cases, for example, linearly or circularly, which may be caused by chiral arrangements of polymers within the aggregate (the polymers themselves may or may not be chiral). These aggregates may find widespread use, for example, in enantiomeric detectors, electrochemical devices, photodetectors, organic diodes, sensors, light sources, or photovoltaic devices.
FILED Tuesday, July 15, 2003
APPL NO 10/621041
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Electricity: Conductors and insulators
174/110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041979 Chrisp
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael P. Chrisp (Danville, California)
ABSTRACT A compact imaging spectrometer comprising an entrance slit for directing light, a first mirror that receives said light and reflects said light, an immersive diffraction grating that diffracts said light, a second mirror that focuses said light, and a detector array that receives said focused light. The compact imaging spectrometer can be utilized for remote sensing imaging spectrometers where size and weight are of primary importance.
FILED Tuesday, September 09, 2003
APPL NO 10/658150
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/339.70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042036 Chung et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Seok-Hwan Chung (Darien, Illinois);  Axel F. Hoffmann (Chicago, Illinois)
ABSTRACT A method for implementing miniaturization of magnetic random access memory (MRAM) and a magnetic memory using single domain switching by direct current are provided. The magnetic memory preferably includes a half-circle or U-shaped architecture with an exchange biasing pad, such as a FeMn exchange biasing pad that effectively generates a head-to-head magnetization configuration. The magnetic memory also includes nanometer scale notches in order to minimize magnetostatic interaction between a single domain memory element and the spin current sources and to effectively trap the magnetic domain wall. Reading the bit can be carried out by anisotropic magnetoresistance, or by other means of determining the magnetization orientation through resistance measurements, such as a spin valve or a magnetic tunneling junction.
FILED Thursday, August 05, 2004
APPL NO 10/912708
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042556 Sun
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) Jiangang Sun (Westmont, Illinois)
ABSTRACT A method and a device to detect subsurface three-dimensional micro-structure in a sample by illuminating the sample with light of a given polarization and detecting light emanating from the sample that has a different direction of polarization by means of a confocal optical system.
FILED Friday, December 05, 2003
APPL NO 10/731772
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/4.70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042615 Richardson
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Thomas J. Richardson (Oakland, California)
ABSTRACT Electrochromic devices having as an active electrode materials comprising Sb, Bi, Si, Ge, Sn, Te, N, P, As, Ga, In, Al, C, Pb, I and chalcogenides are disclosed. The addition of other metals, i.e. Ag and Cu to the active electrode further enhances performance.
FILED Monday, May 19, 2003
APPL NO 10/441855
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/265
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042617 Kosc et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The University of Rochester (Rochester, New York)
INVENTOR(S) Tanya Z. Kosc (Rochester, New York);  Kenneth L. Marshall (Rochester, New York);  Stephen D. Jacobs (Pittsford, New York)
ABSTRACT Optical devices utilizing flakes (also called platelets) suspended in a host fluid have optical characteristics, such as reflective properties, which are angular dependent in response to an AC field. The reflectivity may be Bragg-like, and the characteristics are obtained through the use of flakes of liquid crystal material, such as polymer liquid crystal (PLC) materials including polymer cholesteric liquid crystal (PCLC) and polymer nematic liquid crystal (PNLC) material or birefringent polymers (BP). The host fluid may be propylene carbonate, poly(ethylene glycol) or other fluids or fluid mixtures having fluid conductivity to support conductivity in the flake/host system. AC field dependent rotation of 90° can be obtained at rates and field intensities dependent upon the frequency and magnitude of the AC field. The devices are useful in providing displays, polarizers, filters, spatial light modulators and wherever switchable polarizing, reflecting, and transmission properties are desired.
FILED Wednesday, April 02, 2003
APPL NO 10/405163
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/272
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043204 Reagor et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Los Alamos, New Mexico)
INVENTOR(S) David Reagor (Los Alamos, New Mexico);  Jose Vasquez-Dominguez (Los Alamos, New Mexico)
ABSTRACT A method and apparatus for effective through-the-earth communication involves a signal input device connected to a transmitter operating at a predetermined frequency sufficiently low to effectively penetrate useful distances through-the earth, and having an analog to digital converter receiving the signal input and passing the signal input to a data compression circuit that is connected to an encoding processor, the encoding processor output being provided to a digital to analog converter. An amplifier receives the analog output from the digital to analog converter for amplifying said analog output and outputting said analog output to an antenna. A receiver having an antenna receives the analog output passes the analog signal to a band pass filter whose output is connected to an analog to digital converter that provides a digital signal to a decoding processor whose output is connected to an data decompressor, the data decompressor providing a decompressed digital signal to a digital to analog converter. An audio output device receives the analog output form the digital to analog converter for producing audible output.
FILED Thursday, November 20, 2003
APPL NO 10/719426
ART UNIT 2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Telecommunications
455/40
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07040143 Johnson et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Alliant Techsystems Inc. (Edina, Minnesota)
INVENTOR(S) David L. Johnson (Clinton, Utah);  Karl D. Kersker (Pleasant View, Utah);  David E. Richardson (Brigham City, Utah);  Troy C. Stratton (Brigham City, Utah)
ABSTRACT A method, apparatus and system for testing characteristics of a material sample is provided. The system includes an apparatus configured to house the material test sample while defining a sealed volume against a surface of the material test sample. A source of pressurized fluid is in communication with, and configured to pressurize, the sealed volume. A load applying apparatus is configured to apply a defined load to the material sample while the sealed volume is monitored for leakage of the pressurized fluid. Thus, the inducement of surface defects such as microcracking and crazing may be detected and their effects analyzed for a given material. The material test samples may include laminar structures formed of, for example, carbon cloth phenolic, glass cloth phenolic, silica cloth phenolic materials or carbon-carbon materials. In one embodiment the system may be configured to analyze the material test sample while an across-ply loading is applied thereto.
FILED Thursday, August 28, 2003
APPL NO 10/651311
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/49.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040163 Shcheglov et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Kirill V. Shcheglov (Los Angeles, California);  A. Dorian Challoner (Manhattan Beach, California)
ABSTRACT The present invention discloses an inertial sensor comprising a planar mechanical resonator with embedded sensing and actuation for substantially in-plane vibration and having a central rigid support for the resonator. At least one excitation or torquer electrode is disposed within an interior of the resonator to excite in-plane vibration of the resonator and at least one sensing or pickoff electrode is disposed within the interior of the resonator for sensing the motion of the excited resonator. In one embodiment, the planar resonator includes a plurality of slots in an annular pattern; in another embodiment, the planar mechanical resonator comprises four masses; each embodiment having a simple degenerate pair of in-plane vibration modes.
FILED Tuesday, August 12, 2003
APPL NO 10/639134
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/504.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07040319 Kelly et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Mark E. Kelly (League City, Texas);  Donald R. Pettit (Houston, Texas)
ABSTRACT Method and apparatus are disclosed for monitoring an oxygen partial pressure in an air mask and providing a tactile warning to the user. The oxygen partial pressure in the air mask is detected using an electrochemical sensor, the output signal from which is provided to a comparator. The comparator compares the output signal with a preset reference value or range of values representing acceptable oxygen partial pressures. If the output signal is different than the reference value or outside the range of values, the air mask is vibrated by a vibrating motor to alert the user to a potentially hypoxic condition.
FILED Friday, February 22, 2002
APPL NO 10/087866
ART UNIT 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
128/204.220
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041294 Staats et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
Energy Frontier Research Centers (EFRC)
Photosynthetic Antenna Research Center (PARC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Herman F. Staats (Durham, North Carolina);  Barton F. Haynes (Durham, North Carolina);  Dhavalkumar D. Patel (Durham, North Carolina);  Gregory D. Sempowski (Durham, North Carolina)
ABSTRACT A method of eliciting an immune response against an antigen in a vertebrate subject, the method comprising the steps of providing an antigen-adjuvant composition comprising the antigen and a substantially non-toxic adjuvant molecule having biological activity in mucosal tissues, and administering said antigen-adjuvant composition to the vertebrate subject in a manner such that initial contact occurs in mucosal tissue of the vertebrate subject, whereby an immune response is elicited. Cytokines are preferred adjuvants. Preferred cytokines are interleukin-1α(IL-1α) and interleukin-1β (IL-1β).
FILED Tuesday, June 05, 2001
APPL NO 09/874103
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042199 Birchenough
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Arthur G. Birchenough (Brook Park, Ohio)
ABSTRACT A Series Connected Buck-Boost Regulator (SCBBR) that switches only a fraction of the input power, resulting in relatively high efficiencies. The SCBBR has multiple operating modes including a buck, a boost, and a current limiting mode, so that an output voltage of the SCBBR ranges from below the source voltage to above the source voltage.
FILED Monday, July 28, 2003
APPL NO 10/629875
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Power supply or regulation systems
323/271
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042639 McDowell
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Mark McDowell (Cleveland, Ohio)
ABSTRACT A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to auto-focus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.
FILED Friday, February 04, 2005
APPL NO 11/053760
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/398
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07041759 Sita et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Lawrence R. Sita (Silver Spring, Maryland);  Yonghui Zhang (College Park, Maryland)
ABSTRACT An olefin polymerization pre-catalyst, an activated catalyst and a process for preparing the catalysts are described herein. The pre-catalyst has the formula:
wherein the groups M and R1–R4 are defined herein. The group R4 includes a solid-support.
FILED Thursday, November 20, 2003
APPL NO 10/716604
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
526/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041819 Sessler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Jonathan L. Sessler (Austin, Texas);  Manuel Marquez (Lincolnshire, Illinois);  Pavel Anzenbacher, Jr. (Bowling Green, Ohio);  James A. Shriver (Austin, Texas)
ABSTRACT The present invention provides halogenated calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles having 4–12 pyrrolic rings with greater stability, enhanced anion and neutral molecule binding affinity, and different binding selectivites as compared to their non-halogenated congeners as judged from 1H NMR, 19F NMR and fluorescence emission spectroscopic analyses.
FILED Friday, August 24, 2001
APPL NO 09/939514
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
540/145
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042230 Izadnegahdar
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Alain Izadnegahdar (, None);  ZIN Technologies (, None)
INVENTOR(S) Alain Izadnegahdar (Orange, Ohio)
ABSTRACT Systems and methodologies that provide for multi-parameter sensing via micro fabricated sensing structures operatively connected to oscillators, each micro-fabricated sensing structure in part defines a frequency of a respective associated oscillator. Output from such oscillators can be combined together, and then AC coupled with an incoming DC voltage that feeds the oscillators. The wiring arrangement includes two conducting paths/wires that carry a direct current to the oscillators as well as outputting the combined signal to external measurement devices. In addition, arrangements for pressure sensors are provided that mitigate errors from temperature variations and the induced stress/strains.
FILED Monday, February 28, 2005
APPL NO 11/069801
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/609
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042570 Sailor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael J. Sailor (La Jolla, California);  Sonia Letant (Livermore, California)
ABSTRACT A method for analyzing gaseous or liquid samples is provided. Samples are interacted with pores of a porous thin film. A time-varying response of reflectivity is obtained from the surface of the porous thin film during the interaction. One or more analytes forming the sample or a part of the sample are identified based upon the time-varying response.
FILED Thursday, January 09, 2003
APPL NO 10/339163
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07042649 Quake et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Stephen R. Quake (New York, New York);  Yann Gambin (Paris, France);  Oliver Legrand (Paris, France)
ABSTRACT Soft lithography with surface tension control is used to microfabricate extremely efficient solid immersion lenses (SILs) out of rubber elastomeric material for use in microscope type applications. In order to counteract the surface tension of the mold material in a negative mold that causes creep on a positive mold, material such as RTV is partially cured before use in order to allow the reticulation of polymer chains to change the viscosity of the uncured material in a controllable manner. In a specific embodiment, the techniques of soft lithography with surface tension control are used to make molded SILs out of the elastomer polydimethylsiloxane. The lenses achieve an NA in the range of 1.25. The principle of compound lens design is used to make the first compound solid immersion lens, which is corrected for higher light gathering ability and has a calculated NA=1.32. An important application of these lenses is integrated optics for microfluidic devices, specifically in a handheld rubber microscope for microfluidic flow cytometry.
FILED Tuesday, August 10, 2004
APPL NO 10/915943
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/661
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043710 Reese et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Mississippi State University (Mississippi State, Mississippi)
INVENTOR(S) Robert B. Reese (Starkville, Mississippi);  Mitchell A. Thornton (Dallas, Texas)
ABSTRACT A system and method for early evaluation in micropipeline processors to improve performance is provided. The present invention presents a design methodology where a micropipeline processor block (e.g., a binary full adder) is capable of computing a result based on the arrival of only a subset of inputs. In general, early evaluation allows micropipeline processor blocks to operate in parallel, where they might otherwise operate sequentially because of data arrival dependencies; thereby improving performance of the micropipeline processors.
FILED Tuesday, February 10, 2004
APPL NO 10/774599
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/6
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07041876 Beer et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Steven V. Beer (Ithaca, New York);  David W. Bauer (Kirkland, Washington)
ABSTRACT The present invention relates to a chimeric gene that includes a first DNA molecule encoding a hypersensitive response elicitor protein or polypeptide, a promoter operably linked 5′ to the first DNA molecule to induce transcription of the first DNA molecule in response to activation of the promoter by an oomycete, and a 3′ regulatory region operably linked to the first DNA molecule. Also disclosed are an expression system and a host cell containing the chimeric gene. The present invention also relates to a transgenic plant resistant to disease resulting from oomycete infection, the transgenic plant including the chimeric gene, wherein the promoter induces transcription of the first DNA molecule in response to infection of the plant by an oomycete. Transgenic seeds and transgenic cultivars obtained from the transgenic plant are also disclosed. Additional aspects of the present invention include methods of making a recombinant plant cell and a transgenic plant.
FILED Friday, January 26, 2001
APPL NO 09/770693
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/301
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07043318 Barto et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
INVENTOR(S) Larry D. Barto (Austin, Texas);  Steven C. Nettles (Johnson City, Texas);  Yiwei Li (Austin, Texas)
ABSTRACT An automated system is provided in a facility that manufactures m products, where m>0. The system comprises a software object that provides for calculation of one or more bottleneck delta virtual work in process time (“VWIP”) values. Each of the bottleneck delta VWIP values represents the amount of time until one of n bottleneck workstations begins to risk starvation, where n>0. VWIP is the amount of time a bottleneck will stay busy processing WIP that will reach the bottleneck in less time than new lot starts will reach the same bottleneck. In at least one embodiment, each of the bottleneck delta VWIP values is calculated as a mathematical function of virtual WIP time for the corresponding bottleneck workstation and a lower control limit for the corresponding bottleneck workstation. In at least one other embodiment, n>2 and the software object provides for calculation of a plurality of bottleneck delta VWIP values. The software object contains program code that provides for the foregoing functionality either directly or by invoking one or more other objects.
FILED Thursday, May 23, 2002
APPL NO 10/154092
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Generic control systems or specific applications
7/100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07042340 Ewert et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Roger D. Ewert (Nekoosa, Wisconsin);  Steven J. Ylvisaker (Minneapolis, Minnesota);  Tom N. Thiele (Wisconsin Rapids, Wisconsin)
ABSTRACT An animal alerting device system and method for mounting in a vehicle produces a sound that stimulates an alertness response in large animals to reduce the likelihood that the animals will run into a roadway and cause an animal-vehicle crash. The sound produced by the device is a random sound pattern in an audible frequency range. The volume of the sound produced is automatically adjusted for vehicle speed. Different sound patterns may be produced automatically based on different geographical locations of the vehicle in which the device is mounted.
FILED Thursday, August 21, 2003
APPL NO 10/645300
ART UNIT 2632 — Digital Communications
CURRENT CPC
Communications: Electrical
340/384.100
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 07042317 Xiao et al.
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) State of Oregon, acting by and through the Board of Higher Education on behalf of Portland State University (Portland, Oregon)
INVENTOR(S) Haiqiao Xiao (Portland, Oregon);  Rolf Schaumann (Portland, Oregon);  W. Robert Daasch (Portland, Oregon)
ABSTRACT An active inductor circuit implemented in sub-micron CMOS semiconductor technology is usable at gigaHertz frequencies and includes an input node, a non-inverting transconductor circuit comprising a differential pair of NMOS transistors connected to the input node, an inverting transconductor circuit comprising an NMOS transistor connected to an output node of the non-inverting transconductor circuit and connected to the input node in a gyrator feedback configuration. Varactors coupled to the transconductor circuits tune the frequency and Q of the active inductor circuit.
FILED Wednesday, September 08, 2004
APPL NO 10/937062
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/214
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07041444 Virgin
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Herbert W. Virgin (Clayton, Missouri)
ABSTRACT The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto.
FILED Wednesday, January 14, 2004
APPL NO 10/757832
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07041498 Evans et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The Salk Institute for Biological Studies (La Jolla, California);  Ligand Pharmaceuticals, Inc. (San Diego, California);  The Government of the United States of America (Washington, District of Columbia)
INVENTOR(S) Ronald M. Evans (La Jolla, California);  Barry M. Forman (Newport Beach, California);  Cary A. Weinberger (Carrboro, North Carolina)
ABSTRACT Farnesyl pyrophosphate, the metabolically active form of farnesol, is a key precursor in the synthesis of cholesterol, carotenoids, steroid hormones, bile acids and other molecules involved in cellular growth and metabolism. A nuclear receptor has been identified that is transcriptionally activated by farnesol and related molecules. This novel signaling pathway can be modulated by the use of key metabolic intermediates (or analogs and/or derivatives thereof) as transcriptional regulatory signals.
FILED Friday, May 24, 2002
APPL NO 10/155379
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07043024 Dinsmore et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) McAfee, Inc. (Santa Clara, California)
INVENTOR(S) Peter T Dinsmore (Ellicott City, Maryland);  Michael Heyman (Columbia, Maryland);  Peter Kruus (Clarksville, Maryland);  Alan T Sherman (Columbia, Maryland)
ABSTRACT A system and method for reusable efficient key distribution is disclosed. Key distribution is effected through the application of self-repairing groups that obviate the need for key distribution messages in portions of a hierarchical tree. In one embodiment, the self-repairing group is based on a reusable power set.
FILED Wednesday, April 18, 2001
APPL NO 09/836238
ART UNIT 2131 — Digital Communications
CURRENT CPC
Cryptography
380/278
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 09, 2006.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060509.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital