FedInvent™ Patents
Patent Details for Tuesday, May 30, 2006
This page was updated on Sunday, March 26, 2023 at 08:02 PM GMT
Department of Health and Human Services (HHS)
| US 07051737 | Kolobow et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Sevices (Washington, District of Columbia) |
| INVENTOR(S) | Theodor Kolobow (Rockville, Maryland); Lorenzo Berra (San Giacomo, Italy) |
| ABSTRACT | An endotracheal tube cleaning apparatus 10 which can be periodically inserted into the inside of an endotracheal tube 30 to shave away mucus deposits. In a preferred embodiment, this cleaning apparatus 10 comprises a flexible central tube 12 with an inflatable balloon 40 at its distal end. Affixed to the inflatable balloon are one or more shaving rings 70, each having a squared leading edge 72, to shave away mucus accumulations 60. In operation, the uninflated cleaning apparatus 10 is inserted into the endotracheal tube. The balloon 40 is then inflated by a suitable inflation device, such as a syringe 14, until the balloon's shaving rings are pressed against the inside surface of the endotracheal tube. The cleaning apparatus is then pulled out of the endotracheal tube to shave off mucus deposits. |
| FILED | Thursday, February 05, 2004 |
| APPL NO | 10/773570 |
| ART UNIT | 3743 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery 128/207.140 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052545 | Quake et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stephen R. Quake (San Marino, California); Carl L. Hansen (Pasadena, California) |
| ABSTRACT | High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels. |
| FILED | Friday, June 22, 2001 |
| APPL NO | 09/887997 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/68 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052675 | Prusiner et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Stanley B. Prusiner (San Francisco, California); R. Anthony Williamson (San Diego, California); Dennis R. Burton (LaJolla, California) |
| ABSTRACT | Antibodies are disclosed which specifically bind to native PrPSc in situ. Preferred antibodies bind only to the native PrPSc of a particular species e.g., human, cow, sheep, pig, etc. Particularly preferred antibodies bind specifically to a particular isoform of human PrPSc. Preferred antibodies of the invention are (1) produced by phage display methodology, (2) bind specifically to native PrPSc, (3) neutralizes the infectivity of prions, (4) bind to PrPSc in situ and (5) bind 50% or more of PrPSc in a liquid flowable sample. Antibodies of the invention can be bound to a substrate and used to assay a sample (which has any PrPc denatured via proteinase K) for the presence of PrPSc of a specific species which PrPSc is associated with disease. Antibodies which specifically bind to human PrPSc can be labeled and injected carrying out an in vivo diagnostic test to determine if the human is infected with prions associated with disease. The antibodies are preferably produced using phage display technology wherein the genetic material in the phage expressing the antibody is obtained from a mammal with an ablated endogenous PrP protein gene and an endogenous chimeric PrP gene which mammal had been inoculated with PrPSc to induce antibody production. |
| FILED | Wednesday, December 29, 2004 |
| APPL NO | 11/027139 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052676 | Markovitz et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | David M. Markovitz (Ann Arbor, Michigan); Brian R. Lane (Ann Arbor, Michigan); Peter J. Polverini (Falcon Heights, Minnesota); Robert M. Strieter (Sherman Oaks, California) |
| ABSTRACT | Methods are provided for inhibiting or suppressing viral replication in an infected host cell. More specifically, methods are provided for inhibiting or suppressing viral replication in an infected host cell by administering compounds that interfere with the binding of C-X-C chemokines to C-X-C chemokine receptors. Such methods are advantageous for treating viral infections such as human immunodefeciency virus infections. |
| FILED | Thursday, September 20, 2001 |
| APPL NO | 09/961696 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052677 | Raptis et al. |
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| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Raphael Raptis (San Juan, Puerto Rico); Peter Baran (San Juan, Puerto Rico) |
| ABSTRACT | The present invention is directed to an Fe(III) complex comprising a redox-active metal cluster in a chemically inert shell. The inventive complex has electron transfer and paramagnetic properties. |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600267 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052678 | Vanbever et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Rita Vanbever (Brussels, Belgium); Robert S. Langer (Newton, Massachusetts); David A. Edwards (Boston, Massachusetts); Jeffrey Mintzes (Brighton, Massachusetts); Jue Wang (Clifton, New Jersey); Donghao Chen (Lexington, Massachusetts) |
| ABSTRACT | The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to particles suitable for use in the method. In particular, the invention relates to a method for the pulmonary delivery of a therapeutic, prophylactic or diagnostic agent comprising administering to the respiratory tract of a patient in need of treatment, prophylaxis or diagnosis an effective amount of particles comprising a polycationic complexing agent which is complexed with a therapeutic, prophylactic or diagnostic agent or any combination thereof having a charge capable of complexing with the polycationic complexing agent upon association with the bioactive agent. The particles can further comprise a pharmaceutically acceptable carrier. The amount of polycationic complexing agent present in the particles is an amount sufficient to sustain the release of diagnostic, therapeutic or prophylactic agent from the particles. For example, the amount of complexing agent present can be at about 5% weight/weight (w/w) or more of the total weight of the complexing agent and therapeutic, diagnostic or prophylactic agent. Release of the agent from the administered particles occurs in a sustained fashion. |
| FILED | Thursday, March 07, 2002 |
| APPL NO | 10/094955 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052690 | Shatos et al. |
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| ASSIGNEE(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Marie A. Shatos (Athol, Massachusetts); Darlene A. Dartt (Newton, Massachusetts); Jose D. Rios (Woburn, Massachusetts) |
| ABSTRACT | The invention encompasses isolation, culture and characterization of goblet cells in vitro form mammalian conjuctiva. Goblet cells can be cultured from conjunctiva of such mammals as, e.g., humans, rats, mice, rabbits and the like. In another aspect of the invention, the culture of goblet cells has a concentration of pure goblet cells of 10% or greater. |
| FILED | Friday, October 05, 2001 |
| APPL NO | 10/398574 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052696 | Fields et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Howard A. Fields (Marietta, Georgia); Yury E. Khudyakov (Duluth, Georgia) |
| ABSTRACT | Antigenic epitopes of hepatitis C virus (HCV) and mosaic HCV polypeptides useful as reagents in assays for the diagnosis or monitoring of HCV in a biological sample. The antigenic epitopes and mosaic polypeptides are also useful for the construction of immunogenic pharmaceutical compositions, such as vaccines. The mosaic polypeptides are artificial composite proteins constructed from diagnostically relevant antigenic regions derived from different HCV proteins. Preferably, the mosaic polypeptides contain antigenic epitopes from the core protein, NS3 protein, and NS4 protein. The preferred mosaic polypeptides optionally contain an additional antigenic epitope from either the NS4 protein or the NS5a protein or both. |
| FILED | Wednesday, January 10, 2001 |
| APPL NO | 09/758308 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052703 | Pastan et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Ira Pastan (Potomac, Maryland); Magnus Essand (Uppsala, Sweden); Byungkook Lee (Potomac, Maryland); George Vasmatzis (Byron, Minnesota); Curt Wolfgang (Germantown, Maryland); Ulrich Brinkmann (Weilheim, Germany) |
| ABSTRACT | This invention provides nucleic acids containing sequences from a TCRγ transcript from prostate epithelial cells and many breast cancer cells and a T-cell receptor gamma Alternate Reading frame Protein (“TARP”) expressed from the translation of those sequences. Vaccines made from TARP are useful in raising immune responses to cells in which the protein is expressed, including prostate cancer cells and cells of many breast cancers. The invention also provides methods for diagnosing the presence of prostate cancer and TARP-expressing breast cancers, as well as methods of administering TARP and nucleic acids encoding TARP to subjects. |
| FILED | Wednesday, July 12, 2000 |
| APPL NO | 10/031158 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/277.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052830 | Branch et al. |
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| INVENTOR(S) | Andrea D. Branch (New York, New York); Jose L. Walewski (Eastchester, New York); Decherd D. Stump (New York, New York) |
| ABSTRACT | Novel hepatitis C virus (HCV) polypetides are provided which are not encoded by the standard HCV open reading frame. These alternate reading frame polypeptides are useful, inter alia, in vaccine compositions, in diagnosing HCV infection, and as therapeutic targets. |
| FILED | Wednesday, June 09, 1999 |
| APPL NO | 09/719277 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052834 | Kidd et al. |
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| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Vincent J. Kidd (Memphis, Tennessee); Jill M. Lahti (Memphis, Tennessee); Tal Teitz (Cordova, Tennessee) |
| ABSTRACT | The present invention relates to identification of tumor suppressor activity of a protein, caspase-8 (CASP8), and to related diagnostic and therapeutic compositions and methods. The discovery of this tumor suppressor activity provides screening targets as well, particularly screening for compounds that overcome gene inactivation that results from genomic methylation of the promoter. In particular, CASP8 is functionally inactivated in greater than 90% of all MYCN amplified neuroblastoma cell lines analyzed. Inactivation of CASP8 was observed to occur by homozygous deletion, heterozygous deletion coupled with gene silencing by methylation, and homozygous gene silencing by methylation. A PCR methylation analysis for inactivation of CASP8 is described. |
| FILED | Thursday, December 30, 1999 |
| APPL NO | 09/477082 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052836 | Morrison et al. |
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| ASSIGNEE(S) | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Christine J. Morrison (Decatur, Georgia); Errol Reiss (Chamblee, Georgia); Jong Soo Choi (Taegu, South Korea); Liliana Aidorevich (Maracay Edo Aragua, Venezuela) |
| ABSTRACT | Nucleic acids for detecting Aspergillus species and other filamentous fungi are provided. Unique internal transcribed space 2 coding regions permit the development of nucleic acid probes specific for five different species of Aspergillus, three species of Fusarium, four species of Mucor, two species of Penecillium, five species of Rhizopus, one species of Rhizomucor, as well as probes for Absidia corymbifer, Cunninghamella elagans, Pseudallescheria boydii, and Sporothrix schenkii. Methods are disclosed for the species-specific detection and diagnosis of infection by Aspergillus, Fusarium, Mucor, Penecillium, Rhizomucor, absidia, Cunninghaemella, Pseudallescheria or Sporthrix in a subject. Furthermore, genus-specific probes are also provided for Aspergillus, Fusarium and Mucor, in addition to an all-fungus nucleic acid probe. |
| FILED | Monday, January 14, 2002 |
| APPL NO | 10/046955 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052843 | Li et al. |
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| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Dangsheng Li (Forest Hills, New York); James Yopp, Jr. (New York, New York); Herbert H. Samuels (New Rochelle, New York) |
| ABSTRACT | The present invention relates to a method for detecting the post-translational modification of a target protein by a post translational modifier polypeptide molecule; a method for screening a candidate protein for E3 ligase activity; a method of screening a test compound for the ability to regulate the post-translational modification of a target protein by a post-translational modifier polypeptide molecule; and a method for the large-scale detection of candidate target proteins of post-translational modification by a modifier polypeptide molecule. The present invention also relates to a kit for determining whether a test protein is post-translationally modified by a modifier polypeptide molecule; a kit for screening a test compound for the ability to regulate the post-translational modification of a target protein by a post-translational modifier peptide molecule, and another kit for determining whether a test protein is post-translationally modified by a modifier polypeptide molecule. |
| FILED | Tuesday, October 08, 2002 |
| APPL NO | 10/267141 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052847 | Korlach et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Wednesday, December 15, 2004 |
| APPL NO | 11/013578 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052856 | Ting |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kang Ting (Beverly Hills, California) |
| ABSTRACT | This invention pertains to the discovery that the human NELL-1 gene induces or upregulates bone mineralization. The NELL-1 gene or gene product thus provides a convenient target for screening for modulators of bone mineralization. In addition, NELL-1 can be used to facilitate repair of bone fractures and/or to generally increase bone density. |
| FILED | Tuesday, October 05, 1999 |
| APPL NO | 09/412297 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052858 | Gray et al. |
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| ASSIGNEE(S) | BIOSITE Incorporated (San Diego, California) |
| INVENTOR(S) | Jeff Gray (Solano Beach, California); Gunars E. Valkirs (Escondido, California); Joe Buechler (Carlsbad, California) |
| ABSTRACT | This invention provides a novel Cryptosporidium parvum protein disulfide isomerase polypeptide, and nucleic acids that encode this polypeptide. The invention also provides methods, reagents, and kits that are useful for diagnosing infection by Cryptosporidium parvum. The methods are based on the discovery of binding agents, including recombinant polyclonal antibodies, that bind to the protein disulfide isomerase polypeptide of C. parvum. |
| FILED | Thursday, June 07, 2001 |
| APPL NO | 09/877933 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052859 | Batra et al. |
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| ASSIGNEE(S) | The Board of Regents of the University of Nebraska (Omaha, Nebraska) |
| INVENTOR(S) | Surinder K. Batra (Omaha, Nebraska); Randall E Brand (Omaha, Nebraska); Jöerg Ringel (Rostoct, Germany); Grit Faulmann (Leipzig, Germany); Matthias Löhr (Weinheim, Germany); Grish C. Varshney (Chandigarh, India) |
| ABSTRACT | Methods are provided for the diagnosis of pancreatic cancer. |
| FILED | Thursday, October 24, 2002 |
| APPL NO | 10/279454 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052860 | Handfield et al. |
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| ASSIGNEE(S) | University of Florida Research Foundation (Gainesville, Florida) |
| INVENTOR(S) | Martin Handfield (Gainesville, Florida); Jeffrey Daniel Hillman (Gainesville, Florida); Ann Progulske-Fox (Keystone Heights, Florida) |
| ABSTRACT | Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. |
| FILED | Wednesday, November 28, 2001 |
| APPL NO | 09/995493 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052870 | Sabatini et al. |
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| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | David M. Sabatini (Cambridge, Massachusetts); Do-Hyung Kim (Cambridge, Massachusetts); Dos D. Sarbassov (Shrewsbury, Massachusetts) |
| ABSTRACT | The invention describes isolated mTOR-associated proteins (“mTOR-APs”) as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucleic acid encoding an mTOR-AP polypeptide and methods for producing an mTOR-AP polypeptide. Also described are methods for screening for compounds which modulate mTOR-AP activity and methods for treating or preventing a disorder that is responsive to mTOR-AP modulation. |
| FILED | Wednesday, February 18, 2004 |
| APPL NO | 10/782244 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052874 | Mansfield et al. |
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| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Linda S. Mansfield (Bath, Michigan); Sheila R. Abner (Atlanta, Georgia) |
| ABSTRACT | The present invention provides a heat-stable and protease-resistant antibacterial activity in excretory-secretory products (ESP) of Trichuris suis. The antibacterial activity is not more than 10,000 MW; is resistant to boiling, trypsin, and pronase E; has a bactericidal mode of action; and is effective against Gram positive and Gram negative bacteria, including Escherichia coli, Campylobacter jejuni, Campylobactercoli, and Staphylococcus aureus. The antibacterial activity is useful in applications for killing or inhibiting the growth of microorganisms, in particular bacteria. |
| FILED | Tuesday, November 06, 2001 |
| APPL NO | 10/415166 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/71.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052904 | Zheng et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Changyu Zheng (Rockville, Maryland); Brian O'Connell (Co. Dublin, Ireland); Bruce J. Baum (Bethesda, Maryland) |
| ABSTRACT | An adenovirus, including adenoviral capsid proteins, and a replication-defective adenoviral vector that includes a 5′ retroviral LTR nucleic acid sequence, a 3′ retroviral LTR nucleic acid sequence, a nucleic acid sequence encoding a portion of a retroviral envelope protein adjacent to either the 5′ LTR or the 3′ LTR nucleic acid sequence, a retroviral packaging sequence and a nucleic acid sequence encoding a transgene located between the 5′ LTR and the 3′ LTR is provided. Host cells infected with this adenovirus are also provided. An adenoviral vector is provided that includes an adenoviral polynucleotide sequence comprising a nucleic acid encoding a transgene, a retroviral packaging signal, a 5′ and a 3′ retroviral LTR, and a portion of a retroviral envelope polypeptide, wherein the adenoviral polynucleotide sequence does not encode one or more of E1, E3 or E4. A method for transforming a cell is also provided using a virus or a vector of the invention, as is a method for introducing a transgene into a cell that is not able to produce viral particles with a single viral vector. A method is also provided for preventing or treating disorder in a subject using the adenoviral vectors of the invention. A pharmaceutical composition is also provided that includes an adenoviral vector of the invention and a pharmaceutically acceptable carrier. |
| FILED | Tuesday, January 30, 2001 |
| APPL NO | 10/182644 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052907 | Shi et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Songtao Shi (Gaithersburg, Maryland); Stan Gronthos (Rockville, Maryland); Pamela Gehron Robey (Bethesda, Maryland) |
| ABSTRACT | The present invention provides a culture of isolated adult human dental pulp stem cells that can differentiate into dentin/pulp tissue that can be used to produce a tooth in a human being. The present invention further provides a method of regenerating human dentin/pulp tissue. |
| FILED | Monday, July 23, 2001 |
| APPL NO | 10/333522 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07052915 — Selective labeling and isolation of phosphopeptides and applications to proteome analysis
| US 07052915 | Aebersold et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Ruedi Aebersold (Mercer Island, Washington); Huilin Zhou (Seattle, Washington) |
| ABSTRACT | A method for selective labeling of phosphate groups in natural and synthetic oligomers and polymers in the presence of chemically related groups such as carboxylic acid groups. The method is specifically applicable to biological oligomers and polymers, including phosphopeptides, phosphoproteins and phospholipids. In a specific embodiment, selective labeling of phosphate groups in proteins and peptides, for example, facilitates separation, isolation and detection of phosphoproteins and phosphopeptides in complex mixtures of proteins. Selective labeling can be employed to selectively introduce phosphate labels at phosphate groups in an oligomer or polymer, e.g., in a peptide or protein. Detection of the presence of the label, is used to detect the presence of the phosphate group in the oligomer or polymer. The method is useful for the detection of phosphoproteins or phosphopeptides. The phosphate label can be a colorimetric label, a radiolabel, a fluorescent or phosphorescent label, an affinity label or a linker group carrying a reactive group (or latent reactive group) that allows selective attachment of the oligomer or polymer (protein or peptide) to a phosphate label, to an affinity label or to a solid support. The method can be combined with well-known methods of mass spectrometry to detect and identify phosphopeptides and phosphoproteins. |
| FILED | Tuesday, June 12, 2001 |
| APPL NO | 09/880713 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053041 | Brooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Peter C. Brooks (West Harrison, New York); David A. Cheresh (Encinitas, California); Martin Friedlander (Del Mar, California) |
| ABSTRACT | The present invention describes methods for inhibiting angiogenesis in tissues using vitronectin αvβ5 antagonists. The αvβ5-mediated angiogenesis is correlated with exposure to cytokines including vascular endothelial growth factor, transforming growth factor-α and epidermal growth factor. Inhibition of αvβ5-mediated angiogenesis is particularly preferred in vascular endothelial ocular neovascular diseases, in tumor growth and in inflammatory conditions, using therapeutic compositions containing αvβ5 antagonists. |
| FILED | Friday, May 30, 1997 |
| APPL NO | 09/194552 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053052 | Voellmy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard W. Voellmy (Miami, Florida) |
| ABSTRACT | The present invention relates to exogenous mutant HSF (mutHSF encoded by exogenous DNA) alters expression or synthesis of endogenous heat shock protein (hsp) genes in eukaryotic cells, tissues and organisms (e.g., mammalian, particularly human, cells, tissues and organisms). As described herein, mutHSF has been shown to regulate expression of endogenous hsp in cells and, as a result, to alter the response of the cells to stress. The mutHSF of the present invention is either positively-acting mutHSF or negatively-acting mutHSF. |
| FILED | Wednesday, November 10, 2004 |
| APPL NO | 10/984917 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053071 | Dawson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Marcia Dawson (Los Altos, California); Joseph A. Fontana (West Bloomfield, Michigan); Xiao-kun Zhang (San Diego, California); Mark Leid (Corvallis, Oregon); Ling Jong (Sunnyvale, California); Peter D. Hobbs (Moss Beach, California) |
| ABSTRACT | The present invention provides compounds that are inducers or inhibitors of apoptosis or apoptosis preceded by cell-cycle arrest. In addition, the present invention provides pharmaceutical compositions and methods for treating mammals with leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells. |
| FILED | Monday, December 02, 2002 |
| APPL NO | 10/308241 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/92 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053094 | Malik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cytokinetics, Inc. (South San Francisco, California) |
| INVENTOR(S) | Fady Malik (Burlingame, California); Adam Lewis Tomasi (San Francisco, California); Bainian Feng (Foster City, California); Erica Anne Kraynack (Belmont, California); Kathleen A. Elias (San Francisco, California); Pu-Ping Lu (Foster City, California); Whitney Walter Smith (El Cerrito, California); Xiangping Qian (Foster City, California); David J. Morgans, Jr. (Los Altos, California) |
| ABSTRACT | Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure. |
| FILED | Thursday, January 20, 2005 |
| APPL NO | 11/040478 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/255.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053116 | Schubert et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | David R. Schubert (La Jolla, California); Yuanbin Liu (San Diego, California) |
| ABSTRACT | In accordance with the present invention, there are provided novel methods of blocking amyloid protein toxicity in cells using polycylic compounds. Also provided are novel methods of decreasing amyloid protein production in cells and methods of inhibiting cell death. Invention methods can be used to prevent and treat a diverse class of disease conditions, known as amyloidoses, which are all related to the occurrence of amyloid protein deposits. Invention methods further provide methods of identifying compounds that can block amyloid toxicity or block the amyloid protein induced inhibition of MMT reduction. |
| FILED | Friday, October 11, 2002 |
| APPL NO | 10/269477 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/452 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053119 | Karin et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Charterhouse Therapeutics Ltd. (Oxford, United Kingdom) |
| INVENTOR(S) | Michael Karin (La Jolla, California); Pankaj Kapahi (Pasadena, California) |
| ABSTRACT | The present invention provides methods and compositions for inhibiting IKK, as well as methods and compositions for identifying compounds with activity as inhibitors of IKK, and methods and compositions for the treatment of diseases and/or conditions wherein IKK is implicated and inhibition of its activity is desired. In addition, the present invention provides methods and compositions for the improving the therapeutic activity of COX2 inhibitors, comprising administering the COX2 to a subject in combination with a compound that inhibits IKK activity. The present invention further provides compositions that comprise compounds that inhibit IKK and COX2. |
| FILED | Friday, February 28, 2003 |
| APPL NO | 10/376470 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/530 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053121 | McNamara et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Peter J. McNamara (San Diego, California); Garret A. FitzGerald (Wayne, Pennsylvania); Deba Chakravarti (Swarthmore, Pennsylvania); Amita Sehgal (Haverford, Pennsylvania) |
| ABSTRACT | The present invention provides methods of effecting a change in the core circadian clock by modulating retinoid nuclear receptors. |
| FILED | Tuesday, March 19, 2002 |
| APPL NO | 10/102430 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/559 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053179 | Root et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael J. Root (Boston, Massachusetts); Michael S. Kay (Cambridge, Massachusetts); David C. Chan (Arcadia, California); Peter S. Kim (Lexington, Massachusetts) |
| ABSTRACT | Five-Helix protein, which comprises the three N-helices and at least two, but not three, of the three C-helices of the trimer-of-hairpin structure of HIV gp41, separated by linkers, such as amino acid residue linkers, is disclosed. Six-Helix protein, which includes the three N-helices and the three C-helices of the trimer-of-hairpin structure of HIV gp41, separated by linkers, is also disclosed. |
| FILED | Friday, December 15, 2000 |
| APPL NO | 09/738945 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053189 | Civelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Oregon Health and Sciences University (Portland, Oregon) |
| INVENTOR(S) | Olivier Civelli (Aesch, Switzerland); Hubert Henri-Marie Van Tol (Toronto, Canada) |
| ABSTRACT | The present invention is directed toward antibodies, particularly monoclonal antibodies, which bind specifically to a novel human D4 dopamine receptor in sensitive and specific immunological assays useful for the detection, quantization, and characterization of human D4 dopamine and dopamine analogues. |
| FILED | Tuesday, August 20, 2002 |
| APPL NO | 10/224260 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053194 | Murphy |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Maureen Murphy (Philadelphia, Pennsylvania) |
| ABSTRACT | Compositions and methods are provided for identifying novel therapeutic agents for the treatment of cancer and other cellular proliferative disorders. |
| FILED | Thursday, March 28, 2002 |
| APPL NO | 10/108877 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053210 | Pandey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York) |
| INVENTOR(S) | Ravindra K. Pandey (Williamsville, New York); Thomas J. Dougherty (Grand Island, New York); Alexander J. Pallenberg (Duvall, Washington) |
| ABSTRACT | A process for the preparation of pyropheophorbide a and its derivatives, including 3-devinyl-3-(1′-hexyloxy)ethyl-pyropheophorbide-a, otherwise known as HPPH, is provided. The process involves treating chlorin e6, in the form of its trimethyl ester, with a base, followed by heating to give pyropheophorbide a, which is converted to HPPH by treatment with acid, followed by hexyl alcohol under basic conditions. |
| FILED | Wednesday, July 02, 2003 |
| APPL NO | 10/613474 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053230 | Serhan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles N. Serhan (Wellesley, Massachusetts); Clary B. Clish (Medford, Massachusetts) |
| ABSTRACT | Aspirin triggered lipid mediators (ATLMs) are disclosed which are useful for the treatment of prevention of inflammation associated with various diseases, including ischemia. |
| FILED | Friday, September 12, 2003 |
| APPL NO | 10/663061 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 554/224 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053236 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Li Deng (Waltham, Massachusetts); Yonggang Chen (Somerville, Massachusetts); Shikai Tian (Waltham, Massachusetts) |
| ABSTRACT | The present invention relates to methods for the synthesis of chiral non-racemic products, e.g., enantiomerically-enriched hemiesters, from prochiral and meso starting materials, e.g., prochiral and meso cyclic anhydrides. The present invention also relates to catalysts for the aforementioned methods, and methods for synthesizing these catalysts. |
| FILED | Thursday, June 12, 2003 |
| APPL NO | 10/460051 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 560/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053263 | Sawyers et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Charles L. Sawyers (Los Angeles, California); Karen A. Klein (Los Angeles, California); Owen N. Witte (Sherman Oaks, California); Robert E. Reiter (Los Angeles, California) |
| ABSTRACT | The present invention provides an immune deficient mouse having a human prostate xenograft of locally advanced or metastatic prostate cancer and uses thereof. |
| FILED | Friday, December 14, 2001 |
| APPL NO | 10/022115 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054002 | Sevick-Muraca et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Eva M. Sevick-Muraca (College Station, Texas); Ralf H. Mayer (McLean, Virginia); Jeffery S. Reynolds (Granger, Indiana) |
| ABSTRACT | A system (20) of the present invention includes light source instrumentation (30) to selectively illuminate a light scattering medium including a luminophore and detection instrumentation (50) to detect multiply scattered light output from the medium in response to illumination by the light source instrumentation (30). A processor (70) is operatively coupled to the detection instrumentation (50) to determine a first optical characterization of the medium from a first multiply scattered light output of a first illumination light wavelength and a second optical characterization of the medium from a second multiply scattered light output of a second illumination light wavelength different than the first illumination light wavelength. The processor (70) is operable to calculate lifetime of the luminophore from the first optical characterization, the second optical characterization, and a multiply scattered emission of the luminophore from the medium in response to excitation. |
| FILED | Friday, October 08, 1999 |
| APPL NO | 10/473303 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/317 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054676 | Hedlund et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Laurence W. Hedlund (Chapel Hill, North Carolina); Anja C. S. Brau (Durham, North Carolina); Charles T. Wheeler (Durham, North Carolina); G. Allan Johnson (Chapel Hill, North Carolina) |
| ABSTRACT | Noninvasive, MR-compatible methods and systems optically detect mechanical cardiac activity by anatomic (e.g., esophageal) movements. Most preferably, esophageal motion is detected optically and is indicative rhythmic cardiac activities. This esophageal motion may then be detected and used to provide a signal indicative of periods of cardiac activity and inactivity. The signal may be further processed so as to generate a trigger signal that may be input to a MR scanner. In such a manner, MR microscopy may be accomplished to acquire information at a specific phase of the cardiac cycle, for example, in synchrony with periods of cardiac inactivity. Moreover, since mechanical cardiac activity is detected and employed, instead of electrical activity as is employed in conventional techniques, the present invention is immune to electromagnetic interference during MR microscopy. As a result, robust cardiac signals may be monitored and gated during 2-dimensional and 3-dimensional in vivo microscopy. The present invention is therefore especially well suited for MR microscopy of small animals, such as laboratory mice and rats. |
| FILED | Tuesday, April 24, 2001 |
| APPL NO | 09/840029 |
| ART UNIT | 3742 — Selective Visual Display Systems |
| CURRENT CPC | Surgery 6/413 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07051532 | Howell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenecady, New York) |
| INVENTOR(S) | Stephen John Howell (West Newbury, Massachusetts); John Carl Jacobson (Melrose, Massachusetts); Timothy P. McCaffrey (Swampscott, Massachusetts); Barry Francis Barnes (Malden, Massachusetts) |
| ABSTRACT | A method facilitates assembling a combustor for a gas turbine engine. The method includes providing a dome assembly that includes at least one cooling slot lip and at least one filler projection, wherein a gap defined between the cooling slot lip and the at least one filler projection has a height defined between cooling slot lip and the at least one filler projection that is substantially uniform through the gap. The method also includes coupling a liner assembly to the dome assembly, such that a combustion chamber is defined by the liner assembly, and coupling an inner and an outer support to the dome assembly, such that the dome assembly extends between the inner and outer supports. |
| FILED | Friday, October 17, 2003 |
| APPL NO | 10/688526 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/772 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051535 | Acker |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Bernard N. Acker (Madison, Alabama) |
| ABSTRACT | Applicant's Differential-Pressure Torque Measurement System generates the torque signal from a differential gas pressure measured across the power turbine. The gas pressure differential is measured by using two pressure taps, the first tap taking the pressure reading of the expanding gas as the gas travels from the gas-generating turbine to the power turbine of the engine and the second tap taking the pressure reading of the gas as it escapes the engine through the exhaust port. The differential between the two pressure readings is determined. The pressure differential is then input to a processor which processes it in a pre-determined fashion along with the rotational speed signal of the power turbine, initial pressure and the temperature measurements of the air as the air is initially inlet into the engine. The result of the processing are various engine parameter indications including the torque. |
| FILED | Monday, February 10, 2003 |
| APPL NO | 10/370296 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/803 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051588 | Maltby |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John D. Maltby (San Diego, California) |
| ABSTRACT | A shock simulation system including a support plane, a first mass element and a first spring element attached between the support plane and the first mass element. Also included, is a second mass element that is attached to the first mass element with a second spring element as well as a cocking apparatus, positioned between the support plane and the second mass element, that is capable of accumulating and storing energy in the spring elements. The system also includes a trigger for releasing the energy stored in the springs and for causing a mechanical shock event that is substantially transferred to the second mass. |
| FILED | Wednesday, June 02, 2004 |
| APPL NO | 10/859310 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/161 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051590 | Lemkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Analog Devices IMI, Inc. (Berkeley, California) |
| INVENTOR(S) | Mark A. Lemkin (El Cerrito, California); William A. Clark (Fremont, California); Thor N. Juneau (Berkeley, California); Allen W. Roessig (Fremont, California) |
| ABSTRACT | A movable microstructure includes a first finger set comprising two or more first fingers affixed to a substrate and extending substantially parallel to a defined displacement axis towards a proof-mass. The movable microstructure further includes a second finger set comprising at least one second finger, each member of the second finger set extending substantially parallel to the displacement axis from the proof-mass, terminating between two first fingers. Each second finger is substantially closer to one of the two first fingers between which it terminates. The first finger set, in conjunction with the second finger set, form two terminals of a capacitor. An electrical circuit is included that provides a voltage across the capacitor to generate a position-dependent force, the position-dependent force having a component along an axis substantially orthogonal to the displacement axis, the magnitude of the position-dependent force varying in proportion to displacement along the displacement axis. |
| FILED | Tuesday, June 13, 2000 |
| APPL NO | 09/593593 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051600 | Cavallaro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul V. Cavallaro (Raynham, Massachusetts); Ali M. Sadegh (Franklin, New Jersey) |
| ABSTRACT | A triaxial testing system of material properties having top and bottom joint assemblies that rotate about and move along a longitudinal axis in response to forces imparted by a testing machine. The joint assemblies are connected together by horizontal and vertical linkage assemblies. The horizontal and vertical linkage assemblies are connected to horizontal and vertical loading and clamping assemblies to thereby transfer in-plane and multi-axial loads from the testing machine and the joint assemblies to a material test specimen. The test specimen is rigidly clamped to the horizontal and vertical clamping assemblies. The bases and ends of the test specimen are shaped for clamping and axial loading. Rigid plates may be disposed over ends of composite test specimens for spatially stabilizing such specimens during testing. The test specimens may include devices to measure and record the axial and shear loads, displacement and strains imparted to the specimens during testing. |
| FILED | Tuesday, December 14, 2004 |
| APPL NO | 10/905076 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/862.41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051607 | Wekluk |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Raymond A. Wekluk (Blacksburg, Virginia) |
| ABSTRACT | An adjustable mounting device comprising: 1) a base having a bottom and opposed orthogonal sides defining a reclining C; 2) a standing C-shaped portion having a bottom leg, a vertical leg and a top leg, the bottom leg lying between the orthogonal opposing sides and positioned by a pair of guide dowels that extend between the orthogonal sides and penetrate the bottom leg and a threaded bolt that penetrates at least one of the opposed orthogonal sides in the direction of the other of the opposed orthogonal sides and engages a threaded aperture in the bottom leg; and 3) a mounting plate suspended from the top leg and above the bottom leg by a threaded bolt that penetrates the top leg and engages a threaded aperture in the mounting plate, a third guide dowel extending from the top leg through the mounting plate, and a mechanism in the mounting plate for retaining an element to be located by the mounting device. |
| FILED | Thursday, March 18, 2004 |
| APPL NO | 10/808708 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/866.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051636 | Snow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey M. Snow (Bloomington, Indiana); Trevor M. Snow (Bloomington, Indiana) |
| ABSTRACT | An electromagnetic weapon that includes semi-randomly arranged antenna elements and a central weapon computer. The antenna elements are coordinated to function as an active phased array capable of finding and executing a resonate mode of a target. The central weapon computer controls all the antenna elements, and is able to determine the location of all the antenna elements. |
| FILED | Tuesday, September 21, 2004 |
| APPL NO | 10/945573 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/1.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051850 | Kienholz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CSA Engineering, Inc. (Mountain View, California) |
| INVENTOR(S) | David A. Kienholz (San Jose, California) |
| ABSTRACT | The invention disclosed is a compact and lightweight hybrid pneumatic-magnetic isolator-actuator capable of large force, substantial stroke and bandwidth actuation with near frictionless operation and vibration isolation with very low break frequency. Pneumatic and magnetic forces are applied to a single carriage comprised primarily of a coaxially arranged air piston and coil. The carriage is driven relative to a frame or housing including an internally mounted cylindrical piston sleeve and magnetic actuator body. A combination of air bearings and air bearing piston construction provide for frictionless motion of the carriage relative to the frame. The pneumatic piston provides the actuation force for both static loads and low frequency dynamic loads. An integrally mounted sensor and control unit determine the pressure error resulting at the pneumatic piston. The control unit utilizes the pressure error to drive a high bandwidth magnetic actuation capability in parallel with the pneumatic actuation capability. An air tank of prescribed volume may be connected to the pneumatic piston for effecting a desired air-spring stiffness upon the isolator-actuator. |
| FILED | Friday, November 21, 2003 |
| APPL NO | 10/718352 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Brakes 188/267 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052174 | Korhonen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charles J. Korhonen (Etna, New Hampshire) |
| ABSTRACT | An apparatus for non-destructively testing the response of a specimen to temperature change. An embodiment temperature cycles a specimen, such as a wet mortar beam, dynamically measuring change in dimension and the temperature of the specimen during the cycle. Among other elements, the apparatus employs an accelerometer, a thermistor, a thermocouple, a temperature controller, linear variable differential transducers (LVDTs), an FFT device, a data logger and a heat tape controller. A typical cycle involves using liquid nitrogen to reduce the temperature in an insulated test chamber from ambient to less than −60° C. and returning to ambient by dispersing the nitrogen with a source of ambient air. Further, in select embodiments, the apparatus measures fundamental frequencies induced by a micro-hammer as measured transversely along a dimension of a specimen during the cooling-warming cycle. Also provided is a method for testing specimens using devices representative of embodiments of the present invention. |
| FILED | Thursday, September 16, 2004 |
| APPL NO | 10/941958 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/55 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052226 | Hoot, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph E. Hoot, Jr. (Media, Pennsylvania); Igor Tirado (Shamong, New Jersey) |
| ABSTRACT | A wheeled platform is positioned between the legs of a marine terminal crane for reception thereon and departure therefrom of a motor truck from which a container is transferred by the crane onto a dockside positioned ship. The container is supported by the platform on tables that are automatically positioned and maintained in operative alignment with the crane spreader bar through which the container is transferred to the crane boom in response to location indicating signals from a sensor grid on the platform. |
| FILED | Friday, August 29, 2003 |
| APPL NO | 10/650662 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Material or article handling 414/354 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052235 | Alford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Mary Ellen Alford (Cincinnati, Ohio); David Edward Bulman (Cincinnati, Ohio) |
| ABSTRACT | A turbine engine shroud segment comprises a body including an outer surface from and along which a segment projection extends away from and in an axial direction. The segment projection includes circumferentially spaced apart segment support surfaces. A shroud hanger comprises a body including an inner surface from and along which a hanger projection extends in an axial direction. The hanger projection includes circumferentially spaced hanger bearing surfaces. In a circumferential turbine engine shroud assembly of shroud segments and hangers, a shroud hanger is assembled between a pair of adjacent shroud segments separated by an axial interface. The hanger projection is in juxtaposition with the interface, and respective segment support surfaces and hanger bearing surfaces are in registry. |
| FILED | Tuesday, June 08, 2004 |
| APPL NO | 10/863434 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/173.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052464 | Wodnicki |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Robert G. Wodnicki (Niskayuna, New York) |
| ABSTRACT | An integrated circuit is fabricated by micromachining a hexagonal array of cMUT elements on top of a substrate comprising a hexagonal array of CMOS cells. Each cMUT element overlies a respective CMOS cell in one-to-one correspondence. During layout of the mask for micromachining the cMUT layer, either the hexagonal pattern or the alignment key is rotated until an axis of symmetry of the hexagonal pattern is aligned with an axis of the alignment key. Later, when the mask is superimposed on the CMOS substrate, the alignment key on the mask is aligned with an alignment key on the substrate. This ensures that the cMUT elements formed by optical lithography will be matched to the CMOS cells. |
| FILED | Thursday, January 01, 2004 |
| APPL NO | 10/751290 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Surgery 6/459 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052546 | Motakef et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cape Simulations, Inc. (Natick, Massachusetts) |
| INVENTOR(S) | Shariar Motakef (Weston, Massachusetts); Aniruddha S. Worlikar (Norwood, Massachusetts) |
| ABSTRACT | A method of growing a crystal on a substrate disposed in a reactor, that provides a reactor chamber in which the substrate is disposed, includes flowing reactive gases inside the reactor chamber toward the substrate, the reactive gases comprising components that are able to bond to each other to form the crystal, and flowing buffer gas in the reactor chamber between the reactive gases and a wall of the reactor, where the flowing buffer gas inhibits at least one of a first material at least one of in and produced by the reactive gases from reaching the reactor wall and a second material produced by the reactor wall from reaching the reactive gases in the reactor chamber before the reactive gases reach the substrate. |
| FILED | Thursday, August 28, 2003 |
| APPL NO | 10/650530 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/84 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052562 | Stec, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United State of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Stec, III (Long Valley, New Jersey); Gartung Cheng (Edison, New Jersey); Brian E. Fuchs (Hackettstown, New Jersey); Gerard Gillen (Milford, Pennsylvania); Neha Mehta (Randolph, New Jersey) |
| ABSTRACT | High explosives suitable for filling very small volume loading holes in micro-electric initiators for micro-electro-mechanical mechanisms, used as safe and arm devices, are prepared from slurries of crystalline energetic materials and applied using various methods. These methods include swipe loading, pressure loading and syringe loading. A volatile mobile phase may be added to the slurry so as to partially dissolve the energetic material so that, upon evaporation of the mobile phase, the energetic material precipitates and adheres to the loading hole. |
| FILED | Friday, February 28, 2003 |
| APPL NO | 10/248904 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive and thermic compositions or charges 149/19.920 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052591 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | TheraSense, Inc. (Alameda, California) |
| INVENTOR(S) | Zhiqiang Gao (Austin, Texas); Adam Heller (Austin, Texas); Murielle Dequaire (Dijon, France) |
| ABSTRACT | Thin films of transition metal complex-based redox polymers are electrodeposited on electrodes. When hydrated, an electrodeposited film conducts electrons by electron exchange between backbone-bound, but mobile, functional segments of its redox polymer constituents. These functional segments, or redox complexes, have labile ligands in their inner coordination spheres. The backbones of the redox polymers have strongly coordinating ligands. Electrodeposition results from coordinative crosslinking by exchange of labile ligands and strongly coordinating ligands between polymer chains. When a biological macromolecule or protein, such as a redox enzyme, is added to the solution from which the redox polymer is electrodeposited, it is co-electrodeposited on the electrode surface. When the co-deposited film contains redox enzymes, for example, the modified electrode may be used to catalyze the electrooxidation or electroreduction of substrates of the enzymes. Electrodes modified according to the invention also have application in chemical or biological assays. |
| FILED | Thursday, September 19, 2002 |
| APPL NO | 10/251513 |
| ART UNIT | 1753 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/490 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052607 | Kulick, III |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Kulick, III (Gaithersburg, Maryland) |
| ABSTRACT | Wastewater is delivered to a single tank of a bioreactor system to undergo biological treatment. After undergoing such biological treatment, the wastewater is centrifugally separated outside the tank into contaminated portions with lowered and increased concentration of solids therein to respectively undergo filtration within a small volume chamber of the tank and continuous return to a large volume chamber for biological retreatment during operation of the bioreactor system. Under different conditions of the wastewater delivered to the tank, one of the separated portions of the biologically treated wastewater is disposed of by direct discharge in by-pass relation to the small chamber when delivery thereof into the small chamber is interrupted under selective valve control. |
| FILED | Friday, January 16, 2004 |
| APPL NO | 10/758559 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/607 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052613 | Harmless, II et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | H. Martin Harmless, II (Indianapolis, Indiana); Robert L. Plummer (Indianapolis, Indiana) |
| ABSTRACT | A method and apparatus for using a combination of sonication and ozone to decontaminate pressurized water. The process includes pumping water from a source, such as a creek, river, pond or the like. The water is strained and filtered, and then transferred to a treatment container where it is pressurized for treatment with ozone and ultrasound. The treated water is then piped to a storage tank for subsequent use. The uninterrupted sequential transfer of water from the source, through a treatment container and to the storage tank is accomplished automatically by way of electronic sensors, valves and pumps that are made to communicate with a central processor control unit. |
| FILED | Tuesday, June 24, 2003 |
| APPL NO | 10/602902 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/748 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052617 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Karen Huang (Hsin-Chu, Taiwan); Christophe Pierrat (Msin-Chu, Taiwan) |
| ABSTRACT | A process for producing multiple undercut profiles in a single material. A resist pattern is applied over a work piece and a wet etch is performed to produce an undercut in the material. This first wet etch is followed by a polymerizing dry etch that produces a polymer film in the undercut created by the first wet etch. The polymer film prevents further etching of the undercut portion during a second wet etch. Thus, an undercut profile can be obtained having a larger undercut in an underlying portion of the work piece, utilizing only a single resist application step. The work piece may be a multi-layer work piece having different layers formed of the same material, or it may be a single layer of material. |
| FILED | Friday, December 13, 2002 |
| APPL NO | 10/318021 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Etching a substrate: Processes 216/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052741 | Medeiros et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Maria G. Medeiros (Bristol, Rhode Island); Eric G. Dow (Barrington, Rhode Island); Russell R. Bessette (Mattapoisett, Massachusetts); Craig M. Deschenes (Somerset, Massachusetts); Christopher N. Lafratta (Brighton, Massachusetts); Armand F. Lewis (Mattapoisett, Massachusetts); Yong K. Kim (Dartmouth, Massachusetts) |
| ABSTRACT | A method is provided for the fabrication of a fibrous structure. Fibers are deposited in a hopper connected to an electrode. A mesh covers the hopper opening and the hopper is inverted and suspended over an adhesive coated substrate. An electric field is generated between the hopper and the substrate while the hopper is simultaneously shaken. As a result, fibers fall through the mesh, aligned along the electric field lines, travel through the electric field, and are coupled on one end thereof to the adhesive. |
| FILED | Tuesday, May 18, 2004 |
| APPL NO | 10/847765 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/464 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052821 | Kohl et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Paul A. Kohl (Atlanta, Georgia); Paul Jayachandran Joseph (Atlanta, Georgia); Hollie Reed (Mableton, Georgia); Sue Bidstrup-Allen (Atlanta, Georgia); Celesta E. White (Katy, Texas); Clifford Henderson (Douglasville, Georgia) |
| ABSTRACT | Polymers, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary polymer, among others, includes, a composition having a sacrificial polymer and a photoacid generator. |
| FILED | Friday, October 31, 2003 |
| APPL NO | 10/699330 |
| ART UNIT | 1752 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052848 | Hartman et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Laurie J. Hartman (Germantown, Maryland); David A. Norwood, Jr. (Thurmont, Maryland); Leonard P. Wasieloski, Jr. (Frederick, Maryland) |
| ABSTRACT | Disclosed herein are isolated nucleic acid molecules that may be used as an internal positive controls in probe-based nucleic acid assays such as TaqMan® based assays. Also disclosed are probes comprising the isolated nucleic acid molecule of the present invention. The probes may comprise a reporter molecule and a quencher molecule. Also disclosed are assays which comprise using the probe of the present invention. The probes may be used to distinguish false negative results from true negative results in assays for a target nucleic acid molecule. The probe may be used in conjunction with probe-based nucleic acid assays for the detection of an organism such as one belonging to Bacillus, Mycobacterium, Francisella, Brucella, Clostridium, Yersinia, Variola, Orthopox, or Burkholderia. |
| FILED | Wednesday, December 22, 2004 |
| APPL NO | 11/018377 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052878 | Callahan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Johnny Dale Callahan (Severn, Maryland); Joseph John Temenak (Takoma Park, Maryland) |
| ABSTRACT | Five fluorogenic probe hydrolysis reverse transcriptase-polymerase chain reaction (RT-PCR) (TaqMan™) assays are described for serotype-specific detection of dengue 1–4 and group-specific detection of dengue viruses. Type- and group-specific oligonucleotide primers and fluorogenic probes were designed against conserved regions of the dengue genome. The invention provides TaqMan PCR assays, which are rapid, sensitive, and specific screening and serotyping tools for the epidemiological study of dengue infections. |
| FILED | Wednesday, September 29, 2004 |
| APPL NO | 10/952584 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052923 | Raina |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Kanwal K. Raina (Boise, Idaho) |
| ABSTRACT | This invention provides a conductive aluminum film and method of forming the same, wherein a non-conductive impurity is incorporated into the aluminum film. In one embodiment, the introduction of nitrogen creates an aluminum nitride subphase which pins down hillocks in the aluminum film to maintain a substantially smooth surface. The film remains substantially hillock-free even after subsequent thermal processing. The aluminum nitride subphase causes only a nominal increase in resistivity (resistivities remain below about 12 μΩ-cm), thereby making the film suitable as an electrically conductive layer for integrated circuit or display devices. |
| FILED | Wednesday, September 01, 2004 |
| APPL NO | 10/931314 |
| ART UNIT | 2823 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053429 | Katti |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Romney R. Katti (Maple Grove, Minnesota) |
| ABSTRACT | A bias-adjusted giant magnetoresistive (GMR) device includes a ferromagnetic reference layer, which has a magnetization that remains relatively fixed when a range of magnetic fields is applied, and a ferromagnetic switching layer, which has a magnetization that can be changed by applying a relatively small magnetic field. In MRAM applications, the switching layer stores data in the form of the particular orientation of its magnetization relative to the magnetization of the reference layer. At least one of the reference and switching layers is split into at least two ferromagnetic layers separated by one or more layers of a nonmagnetic conductor, such that the hysteresis curve of resistance versus applied magnetic field is substantially symmetric about zero applied magnetic field. |
| FILED | Thursday, November 06, 2003 |
| APPL NO | 10/702974 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053430 | Katti |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Romney R. Katti (Maple Grove, Minnesota) |
| ABSTRACT | A giant magnetoresistive memory device includes a magnetic sense layer, a magnetic storage layer, a non-magnetic spacer layer between the magnetic sense layer and the magnetic storage layer, and an antiferromagnetic layer formed in proximity to the magnetic storage layer. The antiferromagnetic layer couples magnetically in a controlled manner to the magnetic storage layer such that the magnetic storage layer has uniform and/or directional magnetization. Additionally or alternatively, an antiferromagnetic layer may be formed in proximity to the magnetic sense layer. The antiferromagnetic layer in proximity to the magnetic sense layer couples magnetically in a controlled manner to the magnetic sense layer such that the magnetic sense layer has uniform and/or directional magnetization. |
| FILED | Wednesday, November 12, 2003 |
| APPL NO | 10/706068 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053523 | Ballato et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Arthur Ballato (Oceanport, New Jersey); Richard H. Wittstruck (Howell, New Jersey); Xiaojun Tong (Wuxi, China PRC); Yicheng Lu (East Brunswick, New Jersey) |
| ABSTRACT | An Interdigital Bulk Acoustic-Wave Transducer (IBAT) device is provided with pairs of exciting electrode fingers disposed sufficiently close together on the piezoelectric substrate and dielectric coating over the exciting electrode fingers to generate an IC-compatible voltage at relatively high electric field strength, resulting in a reduced region of excitation and uniform electric field strength distribution. The IBAT advantageously produces a lateral electric field substantially uniform over a substantial portion of the active BAW structure area, reducing, or virtually eliminating sharp voltage spikes, an electrical field produced by the low voltages resident on integrated circuit (IC) chips, usually of a magnitude of 10 volts, or lower, the planar electrode structure being compatible with IC processing techniques, such as photolithography and the BAWs produced thereby being essentially plane waves, with propagation away from, but with phase progression substantially parallel to, the substrate surface. Numerous IBAT structural arrangements are possible by advantageously over-coating the IBAT electrode finger stripes with an insulating dielectric in different configurations, and any possible configuration achieved through over-coating is considered to be within the contemplation of the devices and methods of the present invention. Interdigital bulk acoustic wave transducers and methods for exciting bulk acoustic waves with interdigital electrode fingers are also provided. |
| FILED | Monday, February 02, 2004 |
| APPL NO | 10/774645 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/313.B00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053547 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey); The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Min-Hao Michael Lu (Lawrenceville, New Jersey); James C. Sturm (Princeton, New Jersey); Conor Francis Madigan (Cambridge, Massachusetts); Raymond Kwong (Plainsboro, New Jersey) |
| ABSTRACT | A device is provided. The device includes a substrate, a first electrode disposed over the substrate, a small molecule organic emissive layer disposed over the first electrode, and a second electrode disposed over the organic emissive layer. The substrate has a first index of refraction, and the organic emissive layer has a second index of refraction. The first index of refraction is higher than the second index of refraction. The device may have an external electroluminescent efficiency of at least about 56%. Bulky substituents or dopants may be used to decrease the index of refraction and/or the density of the organic emissive layer. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/305927 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/506 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053772 | Wagner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Thomas A. Wagner (Arlington, Virginia); John A. Phelps (Newport, Maine); Valerie Guralnik (Orono, Minnesota); Ryan A. VanRiper (Maple Grove, Minnesota) |
| ABSTRACT | A system for coordinating the activity of a plurality of humans in teams with a central automated controller having reasoning capability based on a predetermined set of criteria by sending messages to and from each of the humans. The controller processes input from each of the humans in accordance with programmed decision making capability to accomplish predetermined objectives and provide output to at least some of the humans to assess a situation, direct steps in response thereto and coordinate decisions based on a predetermined model and task assessment reasoning to determine the best way to accomplish the predetermined objectives. The coordinator assesses changes to the situation, and makes decisions about the various tasks to be performed and when they are to be begun. Outputs to the humans may be instructions, questions, information and combinations thereof. |
| FILED | Tuesday, December 30, 2003 |
| APPL NO | 10/748093 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Communications: Electrical 340/539.170 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053814 | Yap |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Daniel Yap (Newbury Park, California) |
| ABSTRACT | An apparatus for preparing a RF radar transmit waveform and for decoding RF return waveforms comprising: a RF-lightwave encoder and a decoding preprocessor to phase-encode the RF radar transmit waveform and partially decode the return signal, the encoder including switched optical delay lines for producing desired RF phase shifts, and the decoding preprocessor including a tapped optical delay line and optical delay lines that counteract the delays imposed by the delay lines of the encoder, wherein the RF-lightwave encoder and the decoders allow shorter compressed pulses and larger pulse-compression ratios to be achieved than can be obtained using conventional electronic approaches. Wideband transmit waveforms can be generated due to the use of the switched optical delay lines and, unlike prior art approaches, is not restricted to single-frequency waveforms. The taps can be weighted to accomplish objectives such as reduction of side lobes in the compressed pulse. |
| FILED | Thursday, January 15, 2004 |
| APPL NO | 10/760021 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054229 | Kitchin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | David A. Kitchin (Laurel, Maryland); Walter S. Allensworth (Poolesville, Maryland) |
| ABSTRACT | An acoustic array comprising a plurality of nodes attached to two or more lines. Some or all of the nodes include an emitting transducer and a receiving hydrophone, and the balance include only a receiving hydrophone. Each emitting transducer has associated electronics comprising a high fidelity amplifier and a stored waveform input to the operational amplifier to drive the amplifier, the output of the amplifier exciting the transducer to emit a chirp having a hyperbolic frequency modulated (HFM) waveform. The frequency spectrum of the HFM chirp lies well below the resonant frequency of the transducer. The chirp emitted by a transducer in the node is received and processed by hydrophones in other nodes with a high fidelity representation of the chirp in a cross-correlation operation. Detected chirps are used to determine a range between the emitting and receiving nodes and a shape measurement of the array. |
| FILED | Tuesday, April 29, 2003 |
| APPL NO | 10/425580 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054230 | Nelson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert S Nelson (San Diego, California) |
| ABSTRACT | Locator device that can be used to aid in the recovery of or to provide positional information about a structure that becomes submerged. The locator device for submerged structures consists of one or more modules. Each module can be customized to incorporate one or more features including a power source, a transmitter or source, a receiver or detector, a fastener means, a computer, buoyancy means, a propulsion means, and a communications means. |
| FILED | Tuesday, April 13, 2004 |
| APPL NO | 10/823072 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054505 | Shyu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Haw-Jye Shyu (Columbia, Maryland) |
| ABSTRACT | A system and method for tracking multiple targets using distributed linear sensor arrays. The system includes a plurality of arrays of sensors for receiving signals from a target; a receiver for receiving signals received by the plurality of sensor arrays; an analog/digital converter for converting the signals received from the sensor arrays to a digital format, if signals are received in an analog format; a digital storage device for storing the digitized data from the sensor arrays; and a computer system for retrieving the stored digitized data from the plurality of sensor arrays and processing the data through the use of a composite Hough transform to determine a track of the target. Embodiments include a computer system and method for processing target data from sensors through the use of a composite Hough transform to determine a track of the target. |
| FILED | Wednesday, September 10, 2003 |
| APPL NO | 10/662172 |
| ART UNIT | 2621 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/281 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055007 | Flautner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ARM Limited (Cambridge, United Kingdom); University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Krisztian Flautner (Cambridge, United Kingdom); David T. Blaauw (Ann Arbor, Michigan); Trevor N. Mudge (Ann Arbor, Michigan); Nam S. Kim (Ann Arbor, Michigan); Steven M. Martin (Ann Arbor, Michigan) |
| ABSTRACT | A memory circuit for use in a data processing circuit is described, in which memory cells have at least two states, each state being determined by both a first voltage level corresponding to a first supply line and a second voltage level corresponding to a second supply line. The memory circuit comprises a readable state in which information stored in a memory cell is readable and an unreadable state in which information stored in said memory cell is reliably retained but unreadable. Changing the first voltage level but keeping the second voltage level substantially constant effects a transition between the readable state and the unreadable state. In use, the static power consumption of the memory cell in the unreadable state is less than static power consumption of the memory cell in the readable state. |
| FILED | Thursday, April 10, 2003 |
| APPL NO | 10/410602 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/156 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07051540 | TeGrotenhuis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Ward E. TeGrotenhuis (Kennewick, Washington); Victoria S. Stenkamp (Richland, Washington) |
| ABSTRACT | Wick-Containing apparatus capable of separating fluids and methods of separating fluids using wicks are disclosed. |
| FILED | Wednesday, April 23, 2003 |
| APPL NO | 10/422367 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration 062/93 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051656 | Koehler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | David R. Koehler (Placitas, New Mexico); Darren A. Hoke (Albuquerque, New Mexico); Louis S. Weichman (Albuquerque, New Mexico); George E. Vernon (Rio Rancho, New Mexico); Randy J. Shul (Albuquerque, New Mexico); Michael H. Beggans (Albuquerque, New Mexico) |
| ABSTRACT | A two-stage acceleration sensing apparatus is disclosed which has applications for use in a fuze assembly for a projected munition. The apparatus, which can be formed by bulk micromachining or LIGA, can sense acceleration components along two orthogonal directions to enable movement of a shuttle from an “as-fabricated” position to a final position and locking of the shuttle in the final position. With the shuttle moved to the final position, the apparatus can perform one or more functions including completing an explosive train or an electrical switch closure, or allowing a light beam to be transmitted through the device. |
| FILED | Thursday, August 14, 2003 |
| APPL NO | 10/641980 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/249 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07051956 | Upatnieks |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Naitonal Laboratories (Livermore, California) |
| INVENTOR(S) | Ansis Upatnieks (Livermore, California) |
| ABSTRACT | Disclosed is a device for increasing entrainment and mixing in an air/fuel zone of a direct fuel injection system. The device comprises an ejector nozzle in the form of an inverted funnel whose central axis is aligned along the central axis of a fuel injector jet and whose narrow end is placed just above the jet outlet. It is found that effective ejector performance is achieved when the ejector geometry is adjusted such that it comprises a funnel whose interior surface diverges about 7° to about 9° away from the funnel central axis, wherein the funnel inlet diameter is about 2 to about 3 times the diameter of the injected fuel plume as the fuel plume reaches the ejector inlet, and wherein the funnel length equal to about 1 to about 4 times the ejector inlet diameter. Moreover, the ejector is most effectively disposed at a separation distance away from the fuel jet equal to about 1 to about 2 time the ejector inlet diameter. |
| FILED | Friday, March 19, 2004 |
| APPL NO | 10/804949 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052561 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | ZhaoPing Lu (Oak Ridge, Tennessee); Chain T. Liu (Oak Ridge, Tennessee) |
| ABSTRACT | A bulk amorphous alloy has the approximate composition: Fe(100−a−b−c−d−e)YaMnbTcMdXe wherein: T includes at least one of the group consisting of: Ni, Cu, Cr and Co; M includes at least one of the group consisting of W, Mo, Nb, Ta, Al and Ti; X includes at least one of the group consisting of Co, Ni and Cr; a is an atomic percentage, and a<5; b is an atomic percentage, and b≦25; c is an atomic percentage, and c≦25; d is an atomic percentage, and d≦25; and e is an atomic percentage, and 5≦e≦30. |
| FILED | Tuesday, August 12, 2003 |
| APPL NO | 10/639377 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Metal treatment 148/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052608 | Shepodd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia National Laboratories (Livermore, California) |
| INVENTOR(S) | Timothy J. Shepodd (Livermore, California); Elizabeth Franklin (Rolla, Missouri); Zane T. Prickett (Golden, Colorado); Alexander Artau (Pleasanton, California) |
| ABSTRACT | A three-dimensional microporous polymer network material, or monolith, cast-to-shape in a microchannel. The polymer monolith, produced by a phase separation process, is capable of trapping and retaining charged protein species from a mixture of charged and uncharged species under the influence of an applied electric field. The retained charged protein species are released from the porous polymer monolith by a pressure driven flow in the substantial absence of the electric field. The pressure driven flow is independent of direction and thus neither means to reverse fluid flow nor a multi-directional flow field is required, a single flow through the porous polymer monolith can be employed, in contrast to prior art systems. The monolithic polymer material produced by the invention can function as a chromatographic medium. Moreover, by virtue of its ability to retain charged protein species and quantitatively release the retained species the porous polymer monolith can serve as a means for concentrating charged protein species from, for example, a dilute solution. |
| FILED | Friday, May 07, 2004 |
| APPL NO | 10/841393 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/635 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052671 | McClaine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Safe Hydrogen, LLC (Lexington, Massachusetts) |
| INVENTOR(S) | Andrew W. McClaine (Lexington, Massachusetts); Jonathan L. Rolfe (N. Easton, Massachusetts); Christopher A. Larsen (Dorchester, Massachusetts); Ravi K. Konduri (Canton, Massachusetts) |
| ABSTRACT | A composition comprising a carrier liquid; a dispersant; and a chemical hydride. The composition can be used in a hydrogen generator to generate hydrogen for use, e.g., as a fuel. A regenerator recovers elemental metal from byproducts of the hydrogen generation process. |
| FILED | Friday, January 11, 2002 |
| APPL NO | 10/044813 |
| ART UNIT | 1754 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/658.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052793 | Formato et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Foster-Miller, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Richard M. Formato (Grafton, Massachusetts); Robert F. Kovar (Wrentham, Massachusetts); Paul Osenar (Watertown, Massachusetts); Nelson Landrau (Marlborough, Massachusetts); Leslie S. Rubin (Newton, Massachusetts) |
| ABSTRACT | The present invention relates to composite solid polymer electrolyte membranes (SPEMs) which include a porous polymer substrate interpenetrated with an ion-conducting material. SPEMs of the present invention are useful in electrochemical applications, including fuel cells and electrodialysis. |
| FILED | Thursday, December 28, 2000 |
| APPL NO | 09/750402 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052847 | Korlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Wednesday, December 15, 2004 |
| APPL NO | 11/013578 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053097 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Chiron Corporation (Emeryville, California) |
| INVENTOR(S) | Peter Schultz (Oakland, California); David B. Ring (Palo Alto, California); Stephen D. Harrison (Berkeley, California); Andrew M. Bray (Victoria, Australia) |
| ABSTRACT | Compounds of formula 1: wherein R1 is alkyl, cycloalkyl, aryl, aralkyl, heteroaryl, or heteroaralkyl, substituted with 0–3 substituents selected from lower alkyl, halo, hydroxy, lower alkoxy, amino, lower alkyl-amino, and nitro; R2 is hydroxy, amino, or lower alkoxy; R3 is H, lower alkyl, lower acyl, lower alkoxy-acyl, or amino-acyl; R4 is H or lower alkyl; and pharmaceutically acceptable salts and esters thereof; are effective inhibitors of GSK3. |
| FILED | Monday, November 06, 2000 |
| APPL NO | 09/707548 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/263.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053256 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ralph T. Yang (Ann Arbor, Michigan); Frances H. Yang (Ann Arbor, Michigan); Akira Takahashi (Nagoya, Japan); Arturo J. Hernandez-Maldonado (Ann Arbor, Michigan) |
| ABSTRACT | A method for removing thiophene and thiophene compounds from liquid fuel includes contacting the liquid fuel with an adsorbent which preferentially adsorbs the thiophene and thiophene compounds. The adsorption takes place at a selected temperature and pressure, thereby producing a non-adsorbed component and a thiophene/thiophene compound-rich adsorbed component. The adsorbent includes either a metal or a metal cation that is adapted to form π-complexation bonds with the thiophene and/or thiophene compounds, and the preferential adsorption occurs by π-complexation. A further method includes selective removal of aromatic compounds from a mixture of aromatic and aliphatic compounds. |
| FILED | Thursday, July 03, 2003 |
| APPL NO | 10/613131 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053265 | Kapranov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees Operating Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Philipp Kapranov (Sunnyvale, California); Krzysztof Szczyglowski (London, Canada) |
| ABSTRACT | The present invention provides a novel bi-directional promoter. The present invention further provides methods of producing proteins of interest and methods of controlling gene expression using the bi-directional promoter. The present invention also provides methods of expressing one or more proteins of interest from a novel bi-directional promoter of the present invention. The present invention thus provides improved methods of regulating gene expression in plants or other organisms and expressing one or more proteins concurrently in a variety of cell types. |
| FILED | Monday, October 01, 2001 |
| APPL NO | 09/969263 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053294 | Tuttle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Midwest Research Institute (Kansas City, Missouri) |
| INVENTOR(S) | John R. Tuttle (Frisco, Colorado); Rommel Noufi (Golden, Colorado); Falah S. Hasoon (Arvada, Colorado) |
| ABSTRACT | A thin-film solar cell (10) is provided. The thin-film solar cell (10) comprises a flexible metallic substrate (12) having a first surface and a second surface. A back metal contact layer (16) is deposited on the first surface of the flexible metallic substrate (12). A semiconductor absorber layer (14) is deposited on the back metal contact. A photoactive film deposited on the semiconductor absorber layer (14) forms a heterojunction structure and a grid contact (24) deposited on the heterjunction structure. The flexible metal substrate (12) can be constructed of either aluminium or stainless steel. Furthermore, a method of constructing a solar cell is provided. The method comprises providing an aluminum substrate (12), depositing a semiconductor absorber layer (14) on the aluminum substrate (12), and insulating the aluminum substrate (12) from the semiconductor absorber layer (14) to inhibit reaction between the aluminum substrate (12) and the semiconductor absorber layer (14). |
| FILED | Friday, July 13, 2001 |
| APPL NO | 10/480880 |
| ART UNIT | 1753 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/265 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053509 | Ryan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | David Thomas Ryan (Niskayuna, New York); Evangelos Trifon Laskaris (Schenectady, New York); Xianrui Huang (Clifton Park, New York) |
| ABSTRACT | A rotating machine comprising a superconductive coil and a temperature sensor operable to provide a signal representative of superconductive coil temperature. The rotating machine may comprise a control system communicatively coupled to the temperature sensor. The control system may be operable to reduce electric current in the superconductive coil when a signal representative of a defined superconducting coil temperature is received from the temperature sensor. |
| FILED | Tuesday, March 30, 2004 |
| APPL NO | 10/813281 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/68.C00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053520 | Zetti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander K. Zetti (Kensington, California); Adam M. Fennimore (Berkeley, California); Thomas D. Yuzvinsky (Berkeley, California) |
| ABSTRACT | A rotational actuator/motor based on rotation of a carbon nanotube is disclosed. The carbon nanotube is provided with a rotor plate attached to an outer wall, which moves relative to an inner wall of the nanotube. After deposit of a nanotube on a silicon chip substrate, the entire structure may be fabricated by lithography using selected techniques adapted from silicon manufacturing technology. The structures to be fabricated may comprise a multiwall carbon nanotube (MWNT), two in plane stators S1, S2 and a gate stator S3 buried beneath the substrate surface. The MWNT is suspended between two anchor pads and comprises a rotator attached to an outer wall and arranged to move in response to electromagnetic inputs. The substrate is etched away to allow the rotor to freely rotate. Rotation may be either in a reciprocal or fully rotatable manner. |
| FILED | Thursday, July 15, 2004 |
| APPL NO | 10/891615 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053610 | Clarke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of th University of California (Oakland, California) |
| INVENTOR(S) | John Clarke (Berkeley, California); Robert McDermott (Louisville, Colorado); Alexander Pines (Berkeley, California); Andreas Heinz Trabesinger (Zurich, Switzerland) |
| ABSTRACT | Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals. |
| FILED | Monday, November 22, 2004 |
| APPL NO | 10/995765 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053788 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | IntelliServ, Inc. (Provo, Utah) |
| INVENTOR(S) | David R Hall (Provo, Utah); Joe R Fox (Provo, Utah) |
| ABSTRACT | A robust transmission element for transmitting information between downhole tools, such as sections of drill pipe, in the presence of hostile environmental conditions, such as heat, dirt, rocks, mud, fluids, lubricants, and the like. The transmission element maintains reliable connectivity between transmission elements, thereby providing an uninterrupted flow of information between drill string components. A transmission element is mounted within a recess proximate a mating surface of a downhole drilling component, such as a section of drill pipe. The transmission element may include an annular housing forming a trough, an electrical conductor disposed within the trough, and an MCEI material disposed between the annular housing and the electrical conductor. |
| FILED | Tuesday, June 03, 2003 |
| APPL NO | 10/453076 |
| ART UNIT | 2635 — Optical Communications |
| CURRENT CPC | Communications: Electrical 340/854.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054008 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mississippi State University (Mississippi State, Mississippi) |
| INVENTOR(S) | Chuji Wang (Starkville, Mississippi); Christopher Winstead (Hattiesburg, Mississippi); Yixiang Duan (Los Alamos, New Mexico) |
| ABSTRACT | Provided is a novel system for conducting elemental measurements using cavity ring-down spectroscopy (CRDS). The present invention provides sensitivity thousands of times improved over conventional devices and does so with the advantages of low power, low plasma flow rate, and the ability being sustained with various gases. |
| FILED | Wednesday, February 19, 2003 |
| APPL NO | 10/367806 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/437 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054011 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Yizheng Zhu (Blacksburg, Virginia); Xingwei Wang (Blacksburg, Virginia); Juncheng Xu (Blacksburg, Virginia); Anbo Wang (Blacksburg, Virginia) |
| ABSTRACT | A fiber optic sensor has a hollow tube bonded to the endface of an optical fiber, and a diaphragm bonded to the hollow tube. The fiber endface and diaphragm comprise an etalon cavity. The length of the etalon cavity changes when applied pressure or acceleration flexes the diaphragm. The entire structure can be made of fused silica. The fiber, tube, and diaphragm can be bonded with a fusion splice. The present sensor is particularly well suited for measuring pressure or acceleration in high temperature, high pressure and corrosive environments (e.g., oil well downholes and jet engines). The present sensors are also suitable for use in biological and medical applications. |
| FILED | Thursday, August 05, 2004 |
| APPL NO | 10/911635 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/480 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054065 | Wolfe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jesse D. Wolfe (Discovery Bay, California); Jerald A. Britten (Oakley, California); Aleksey M. Komashko (San Diego, California) |
| ABSTRACT | A durable silver film thin film coated non-planar optical element has been developed to replace Gold as a material for fabricating such devices. Such a coating and resultant optical element has an increased efficiency and is resistant to tarnishing, can be easily stripped and re-deposited without modifying underlying grating structure, improves the throughput and power loading of short pulse compressor designs for ultra-fast laser systems, and can be utilized in variety of optical and spectrophotometric systems, particularly high-end spectrometers that require maximized efficiency. |
| FILED | Wednesday, November 26, 2003 |
| APPL NO | 10/723116 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/572 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07052668 | Smalley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard E. Smalley (Houston, Texas); Robert H. Hauge (Houston, Texas); Peter Athol Willis (Los Angeles, California); W. Carter Kittrell (Houston, Texas) |
| ABSTRACT | A gas-phase method for producing high yields of single-wall carbon nanotubes with high purity and homogeneity is disclosed. The method involves using preformed metal catalyst clusters to initiate and grow single-wall carbon nanotubes. In one embodiment, multi-metallic catalyst precursors are used to facilitate the metal catalyst cluster formation. The catalyst clusters are grown to the desired size before mixing with a carbon-containing feedstock at a temperature and pressure sufficient to initiate and form single-wall carbon nanotubes. The method also involves using small fullerenes and preformed sections of single-wall carbon nanotubes, either derivatized or underivatized, as seed molecules for expediting the growth and increasing the yield of single-wall carbon nanotubes. The multi-metallic catalyst precursors and the seed molecules may be introduced into the reactor by means of a supercritical fluid. In addition the seed molecules may be introduced into the reactor via an aerosol or smoke. |
| FILED | Tuesday, January 29, 2002 |
| APPL NO | 10/059874 |
| ART UNIT | 1754 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052793 | Formato et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Foster-Miller, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Richard M. Formato (Grafton, Massachusetts); Robert F. Kovar (Wrentham, Massachusetts); Paul Osenar (Watertown, Massachusetts); Nelson Landrau (Marlborough, Massachusetts); Leslie S. Rubin (Newton, Massachusetts) |
| ABSTRACT | The present invention relates to composite solid polymer electrolyte membranes (SPEMs) which include a porous polymer substrate interpenetrated with an ion-conducting material. SPEMs of the present invention are useful in electrochemical applications, including fuel cells and electrodialysis. |
| FILED | Thursday, December 28, 2000 |
| APPL NO | 09/750402 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052821 | Kohl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Paul A. Kohl (Atlanta, Georgia); Paul Jayachandran Joseph (Atlanta, Georgia); Hollie Reed (Mableton, Georgia); Sue Bidstrup-Allen (Atlanta, Georgia); Celesta E. White (Katy, Texas); Clifford Henderson (Douglasville, Georgia) |
| ABSTRACT | Polymers, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary polymer, among others, includes, a composition having a sacrificial polymer and a photoacid generator. |
| FILED | Friday, October 31, 2003 |
| APPL NO | 10/699330 |
| ART UNIT | 1752 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052847 | Korlach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Wednesday, December 15, 2004 |
| APPL NO | 11/013578 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052854 | Melker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Richard J. Melker (Gainesville, Florida); Ronald L. Hayes (Gainesville, Florida); Ka-Wang Kevin Wang (Gainesville, Florida); Donn Michael Dennis (Gainesville, Florida) |
| ABSTRACT | Systems and methods for the ex vivo diagnostic analysis of samples of bodily fluids, including exhaled breath and blood. The present invention uses nanostructure-based assemblies in combination with sensor technology to provide an efficient and accurate means for identifying the presence of a target analyte/biomarker in a sample of bodily fluid. In a preferred embodiment, the nanostructure-based assemblies of the present invention include detecting means such as RNA oligonucleotide chains or “apparatus” and releasable surrogate markers such as DMSO. |
| FILED | Thursday, October 02, 2003 |
| APPL NO | 10/678506 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07052915 — Selective labeling and isolation of phosphopeptides and applications to proteome analysis
| US 07052915 | Aebersold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Ruedi Aebersold (Mercer Island, Washington); Huilin Zhou (Seattle, Washington) |
| ABSTRACT | A method for selective labeling of phosphate groups in natural and synthetic oligomers and polymers in the presence of chemically related groups such as carboxylic acid groups. The method is specifically applicable to biological oligomers and polymers, including phosphopeptides, phosphoproteins and phospholipids. In a specific embodiment, selective labeling of phosphate groups in proteins and peptides, for example, facilitates separation, isolation and detection of phosphoproteins and phosphopeptides in complex mixtures of proteins. Selective labeling can be employed to selectively introduce phosphate labels at phosphate groups in an oligomer or polymer, e.g., in a peptide or protein. Detection of the presence of the label, is used to detect the presence of the phosphate group in the oligomer or polymer. The method is useful for the detection of phosphoproteins or phosphopeptides. The phosphate label can be a colorimetric label, a radiolabel, a fluorescent or phosphorescent label, an affinity label or a linker group carrying a reactive group (or latent reactive group) that allows selective attachment of the oligomer or polymer (protein or peptide) to a phosphate label, to an affinity label or to a solid support. The method can be combined with well-known methods of mass spectrometry to detect and identify phosphopeptides and phosphoproteins. |
| FILED | Tuesday, June 12, 2001 |
| APPL NO | 09/880713 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053097 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Chiron Corporation (Emeryville, California) |
| INVENTOR(S) | Peter Schultz (Oakland, California); David B. Ring (Palo Alto, California); Stephen D. Harrison (Berkeley, California); Andrew M. Bray (Victoria, Australia) |
| ABSTRACT | Compounds of formula 1: wherein R1 is alkyl, cycloalkyl, aryl, aralkyl, heteroaryl, or heteroaralkyl, substituted with 0–3 substituents selected from lower alkyl, halo, hydroxy, lower alkoxy, amino, lower alkyl-amino, and nitro; R2 is hydroxy, amino, or lower alkoxy; R3 is H, lower alkyl, lower acyl, lower alkoxy-acyl, or amino-acyl; R4 is H or lower alkyl; and pharmaceutically acceptable salts and esters thereof; are effective inhibitors of GSK3. |
| FILED | Monday, November 06, 2000 |
| APPL NO | 09/707548 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/263.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053157 | Sita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Lawrence R Sita (Silver Spring, Maryland); Richard J Keaton (Greenbelt, Maryland); Kumudini C Jayaratne (Bartelsville, Oklahoma) |
| ABSTRACT | The present invention relates to a method of producing multimodal polyolefins using at least one or more activated metallocene catalysts. The activated metallocene catalysts are used in combination in a single-process method. The method allows for the production of multimodal polyolefins of tunable composition, molecular weight and polydispersity. |
| FILED | Friday, July 19, 2002 |
| APPL NO | 10/484210 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 526/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053204 | Keller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nancy P. Keller (Madison, Wisconsin); Jin Woo Bok (Madison, Wisconsin) |
| ABSTRACT | The invention provides polypeptides and nucleic acids which identify and encode LaeA, a regulator of fungal secondary metabolite production which exhibits global control over secondary metabolite biosynthetic gene clusters. The invention further provides expression vectors, host cells, methods of increasing the production of secondary metabolites in an organism naturally producing a secondary metabolite or engineered to produce a secondary metabolite, and methods of identifying novel secondary metabolite biosynthesis gene clusters. |
| FILED | Tuesday, September 23, 2003 |
| APPL NO | 10/668696 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.740 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053221 | Hedrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | James Lupton Hedrick (Pleasanton, California); Gregory Walker Nyce (San Jose, California); Robert M. Waymouth (Palo Alto, California) |
| ABSTRACT | A method is provided for carrying out depolymerization of a polymer containing electrophilic linkages in the presence of a catalyst and a nucleophilic reagent, wherein production of undesirable byproducts resulting from polymer degradation is minimized. The reaction can be carried out at a temperature of 80° C. or less, and generally involves the use of an organic, nonmetallic catalyst, thereby ensuring that the depolymerization product(s) are substantially free of metal contaminants. In an exemplary depolymerization method, the catalyst is a carbene compound such as an N-heterocyclic carbene, or is a precursor to a carbene compound. The method provides an important alternative to current recycling techniques such as those used in the degradation of polyesters, polyamides, and the like. |
| FILED | Thursday, January 30, 2003 |
| APPL NO | 10/355554 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053256 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ralph T. Yang (Ann Arbor, Michigan); Frances H. Yang (Ann Arbor, Michigan); Akira Takahashi (Nagoya, Japan); Arturo J. Hernandez-Maldonado (Ann Arbor, Michigan) |
| ABSTRACT | A method for removing thiophene and thiophene compounds from liquid fuel includes contacting the liquid fuel with an adsorbent which preferentially adsorbs the thiophene and thiophene compounds. The adsorption takes place at a selected temperature and pressure, thereby producing a non-adsorbed component and a thiophene/thiophene compound-rich adsorbed component. The adsorbent includes either a metal or a metal cation that is adapted to form π-complexation bonds with the thiophene and/or thiophene compounds, and the preferential adsorption occurs by π-complexation. A further method includes selective removal of aromatic compounds from a mixture of aromatic and aliphatic compounds. |
| FILED | Thursday, July 03, 2003 |
| APPL NO | 10/613131 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053439 | Kan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edwin Kan (Ithaca, New York); Bradley A. Minch (Ithaca, New York) |
| ABSTRACT | A field effect transistor has a floating gate with an extended portion. A selectively chemoreceptive finger or layer is electrostatically coupled to the extended portion of the floating gate, and induces a voltage on the gate in response to selected chemicals or other conditions affecting the finger. The voltage on the gate modulates current flowing between a source and a drain of the transistor, effectively sensing the presence of the selected chemicals or conditions. In one embodiment, multiple chemoreceptive fingers are electrostatically coupled to the extended portion of the floating gate. In a further embodiment, an array of such field effect transistors provide a sensor for multiple conditions. |
| FILED | Tuesday, October 28, 2003 |
| APPL NO | 10/695432 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/315 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053547 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey); The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Min-Hao Michael Lu (Lawrenceville, New Jersey); James C. Sturm (Princeton, New Jersey); Conor Francis Madigan (Cambridge, Massachusetts); Raymond Kwong (Plainsboro, New Jersey) |
| ABSTRACT | A device is provided. The device includes a substrate, a first electrode disposed over the substrate, a small molecule organic emissive layer disposed over the first electrode, and a second electrode disposed over the organic emissive layer. The substrate has a first index of refraction, and the organic emissive layer has a second index of refraction. The first index of refraction is higher than the second index of refraction. The device may have an external electroluminescent efficiency of at least about 56%. Bulky substituents or dopants may be used to decrease the index of refraction and/or the density of the organic emissive layer. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/305927 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/506 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053813 | Hubbert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| INVENTOR(S) | John Clark Hubbert (Fort Collins, Colorado); Venkatachalam Chandraskaran (Fort Collins, Colorado) |
| ABSTRACT | A radar system determines the range and velocity of a target, such as an atmospheric structure. The radar system transfers a first series of pulses and a second series of pulses. The first series of pulses and the second series of pulses have orthogonal polarizations. The first series of pulses and the second series of pulses have a same pulse repetition time. The first series of pulses and the second series of pulses are offset by a time amount. The target reflects energy from the first series of pulses to generate a first series of echoes and reflects energy from the second series of pulses to generate a second series of echoes. The radar system processes the first series of echoes and the second series of echoes to determine the range and velocity of the target. |
| FILED | Thursday, April 22, 2004 |
| APPL NO | 10/829602 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/26.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07051765 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Anthony R. Kelley (Madison, Alabama); Paul D. Van Buskirk (Humble, Texas) |
| ABSTRACT | An orifice plate for use in a conduit through which fluid flows is defined by a central circular region having a radius R0 and a ring-shaped region surrounding the central circular region. The ring-shaped region has holes formed therethrough with those holes centered at each radius R thereof satisfying a relationship AR=a/(XRVRb) where AR is a sum of areas of those holes having centers at radius R, XR is a flow coefficient at radius R, VR is a velocity of the fluid that is to flow through the conduit at radius R, b is a constant selected to make at least one process variable (associated with the fluid that is to flow through the conduit) approximately equal at each radius R, and a is a constant that is equal to (XRARVRb) at each radius R. |
| FILED | Friday, December 19, 2003 |
| APPL NO | 10/750628 |
| ART UNIT | 3754 — Fluid Handling and Dispensing |
| CURRENT CPC | Pipes and tubular conduits 138/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07052668 | Smalley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard E. Smalley (Houston, Texas); Robert H. Hauge (Houston, Texas); Peter Athol Willis (Los Angeles, California); W. Carter Kittrell (Houston, Texas) |
| ABSTRACT | A gas-phase method for producing high yields of single-wall carbon nanotubes with high purity and homogeneity is disclosed. The method involves using preformed metal catalyst clusters to initiate and grow single-wall carbon nanotubes. In one embodiment, multi-metallic catalyst precursors are used to facilitate the metal catalyst cluster formation. The catalyst clusters are grown to the desired size before mixing with a carbon-containing feedstock at a temperature and pressure sufficient to initiate and form single-wall carbon nanotubes. The method also involves using small fullerenes and preformed sections of single-wall carbon nanotubes, either derivatized or underivatized, as seed molecules for expediting the growth and increasing the yield of single-wall carbon nanotubes. The multi-metallic catalyst precursors and the seed molecules may be introduced into the reactor by means of a supercritical fluid. In addition the seed molecules may be introduced into the reactor via an aerosol or smoke. |
| FILED | Tuesday, January 29, 2002 |
| APPL NO | 10/059874 |
| ART UNIT | 1754 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053929 | Yadid-Pecht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Orly Yadid-Pecht (Haifa, Israel); Brad Minch (Pasadena, California); Bedabrara Pain (Los Angeles, California); Eric Fossum (La Crescenta, California) |
| ABSTRACT | An imaging system for identifying the location of the center of mass (“COM”) in an image. In one aspect, an imaging system includes a plurality of photosensitive elements arranged in a matrix. A center of mass circuit coupled to the photosensitive elements includes a resistive network and a normalization circuit including at least one bipolar transistor. The center of mass circuit identifies a center of mass location in the matrix and includes: a row circuit, where the row circuit identifies a center of mass row value in each row of the matrix and identifies a row intensity for each row; a horizontal circuit, where the horizontal circuit identifies a center of mass horizontal value; and a vertical circuit, where the vertical circuit identifies a center of mass vertical value. The horizontal and vertical center of mass values indicate the coordinates of the center of mass location for the image. |
| FILED | Tuesday, November 05, 2002 |
| APPL NO | 10/289501 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Television 348/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054114 | Jander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | NVE Corporation (Eden Prairie, Minnesota) |
| INVENTOR(S) | Albrecht Jander (Corvallis, Oregon); Catherine A. Nordman (St. Paul, Minnesota); Zhenghong Qian (Eden Prairie, Minnesota); Carl H. Smith (Chatham, New Jersey) |
| ABSTRACT | A ferromagnetic thin-film based magnetic field sensor with first and second sensitive direction sensing structures each having a nonmagnetic intermediate layer with two major surfaces on opposite sides thereof having a magnetization reference layer on one and an anisotropic ferromagnetic material sensing layer on the other having a length in a selected length direction and a smaller width perpendicular thereto and parallel to the relatively fixed magnetization direction. The relatively fixed magnetization direction of said magnetization reference layer in each is oriented in substantially parallel to the substrate but substantially perpendicular to that of the other. An annealing process is used to form the desired magnetization directions. |
| FILED | Monday, November 17, 2003 |
| APPL NO | 10/715144 |
| ART UNIT | 2652 — Videophones and Telephonic Communications |
| CURRENT CPC | Dynamic magnetic information storage or retrieval 360/324.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07052668 | Smalley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard E. Smalley (Houston, Texas); Robert H. Hauge (Houston, Texas); Peter Athol Willis (Los Angeles, California); W. Carter Kittrell (Houston, Texas) |
| ABSTRACT | A gas-phase method for producing high yields of single-wall carbon nanotubes with high purity and homogeneity is disclosed. The method involves using preformed metal catalyst clusters to initiate and grow single-wall carbon nanotubes. In one embodiment, multi-metallic catalyst precursors are used to facilitate the metal catalyst cluster formation. The catalyst clusters are grown to the desired size before mixing with a carbon-containing feedstock at a temperature and pressure sufficient to initiate and form single-wall carbon nanotubes. The method also involves using small fullerenes and preformed sections of single-wall carbon nanotubes, either derivatized or underivatized, as seed molecules for expediting the growth and increasing the yield of single-wall carbon nanotubes. The multi-metallic catalyst precursors and the seed molecules may be introduced into the reactor by means of a supercritical fluid. In addition the seed molecules may be introduced into the reactor via an aerosol or smoke. |
| FILED | Tuesday, January 29, 2002 |
| APPL NO | 10/059874 |
| ART UNIT | 1754 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053381 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Jeffrey Jon Shaw (Ballston Lake, New York); Ching-Yeu Wei (Niskayuna, New York); David Francis Fobare (Niskayuna, New York) |
| ABSTRACT | The present invention provides an X-ray detector assembly and a fabrication method, where the X-ray detector assembly includes a scintillator material disposed on a detector matrix array disposed on a detector substrate; and an encapsulating coating disposed on the scintillator material. The encapsulating coating includes a combination of a mono-chloro-poly-para-xylylene layer and a poly-para-xylylene layer. In one embodiment, a poly-para-xylylene layer is disposed over the scintillator material and a mono-chloro-poly-para-xylylene layer is disposed over the poly-para-xylylene layer. |
| FILED | Wednesday, July 30, 2003 |
| APPL NO | 10/631197 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/370.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07054702 | Barto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Larry D. Barto (Austin, Texas); Steven C. Nettles (Johnson City, Texas); Yiwei Li (Austin, Texas) |
| ABSTRACT | A system and method are provided for calculating a plurality of bottleneck delta virtual work in process time (“VWIP”) values. Each of the bottleneck delta VWIP values represents the time until one of n bottleneck workstations begins to risk starvation. |
| FILED | Monday, April 01, 2002 |
| APPL NO | 10/113617 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07052776 | Fanta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of Amercia as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | George F. Fanta (Morton, Illinois); Frederick C. Felker (Morton, Illinois) |
| ABSTRACT | Articles produced from hydrophobic polymers (e.g., polyethylene) are surface-coated with thin films of starch in order to render the surfaces hydrophilic. The thin coatings form on the surfaces of plastic objects when the objects are placed in contact with hot, aqueous solutions of starch. These starch coatings are adherent to the hydrophobic plastic surfaces under both wet and dry conditions, and they permit the surfaces to be uniformly wet with water. The coatings may be rendered even more adherent when wet by graft polymerizing the starch with a synthetic monomer. Resultant products have the potential for improved biocompatibility, improved compatibility with hydrophilic reagents, reduced build-up of electrostatic charge, reduced blocking, reduced friction, improved absorption of water-based dyes, and improved adhesion properties. The starch coatings are non-toxic, inexpensive and biodegradable. |
| FILED | Thursday, May 20, 2004 |
| APPL NO | 10/849977 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Stock material or miscellaneous articles 428/532 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07053243 | Abbott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Fanning Corporation (Chicago, Illinois); The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Thomas P. Abbott (Peoria, Illinois); Alan Wohlman (Northbrook, Illinois) |
| ABSTRACT | 1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods for enhancing the oxidative stability of a lipid comprising supplementing a base lipid in need of enhanced oxidative stability with at least one 1-(3-methoxybenzyl)-3-substituted thiourea compound of the present invention. |
| FILED | Friday, August 01, 2003 |
| APPL NO | 10/633252 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 07053813 | Hubbert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| INVENTOR(S) | John Clark Hubbert (Fort Collins, Colorado); Venkatachalam Chandraskaran (Fort Collins, Colorado) |
| ABSTRACT | A radar system determines the range and velocity of a target, such as an atmospheric structure. The radar system transfers a first series of pulses and a second series of pulses. The first series of pulses and the second series of pulses have orthogonal polarizations. The first series of pulses and the second series of pulses have a same pulse repetition time. The first series of pulses and the second series of pulses are offset by a time amount. The target reflects energy from the first series of pulses to generate a first series of echoes and reflects energy from the second series of pulses to generate a second series of echoes. The radar system processes the first series of echoes and the second series of echoes to determine the range and velocity of the target. |
| FILED | Thursday, April 22, 2004 |
| APPL NO | 10/829602 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/26.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07052837 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Clayton H. Johnson (Little Rock, Arkansas); J. Lyndal York (Little Rock, Arkansas); Joan E. McEwen (Little Rock, Arkansas) |
| ABSTRACT | The present invention describes Histoplasmosis capsulatum catalase A and catalase P nucleic acid and protein sequences as reagents for the detection of H. capsulatum infection. Specifically, the invention describes intron sequences from the H. capsulatum catalase A (CATA) and catalase P (CATP) genes which can be used for hybridization and PCR based detection of H. capsulatum infection. In another embodiment, assays for H. capsulatum catalase P or catalase A polypeptides are used as diagnostic tests for H. capsulatum infection and histoplasmosis, respectively. Also described is the differentiation of H. capsulatum from Blastomyces dermititidis based on a H. capsulatum catalase P PCR based assay. |
| FILED | Wednesday, March 13, 2002 |
| APPL NO | 10/099352 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
General Services Administration (GSA)
| US 07052541 | Chianelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Russell Chianelli (El Paso, Texas); Lori A. Polette (El Paso, Texas) |
| ABSTRACT | The present invention includes a paint or coating composition comprising an organic pigment or dye complexed to the surface of a layered or fibrous inorganic clay. A wide variety of paint colors can be obtained by varying the pH during the preparation as well as by varying the synthesis conditions and changing particle size of the clay. The paint has unprecedented stability. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/370288 |
| ART UNIT | 1755 — Semiconductors/Memory |
| CURRENT CPC | Compositions: Coating or plastic 16/401 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 07055139 | Balle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Susanne M. Balle (Hudson, New Hampshire); David C. P. LaFrance-Linden (Arlington, Massachusetts); Bevin R. Brett (Brookline, New Hampshire); Alexander E. Holmansky (Nashua, New Hampshire) |
| ABSTRACT | A computer system includes an aggregator network that couples a plurality of processes on which an application executes to a debugger user interface. Using the debugger user interface, commands are created and sent through the aggregator network to the processes and messages from the processes are routed through the aggregator network to the debugger user interface. Whenever possible, the aggregator network combines the processors' messages into fewer messages and provides a reduced number of messages to the debugger user interface. The aggregated messages generally contain the same information as the messages they aggregate and identify the processes from which the messages originated. The aggregator network examines the processor messages for messages that have identical or similar data payloads and aggregates messages that have identical or similar payloads. |
| FILED | Thursday, March 28, 2002 |
| APPL NO | 10/109287 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07051659 | Tyll et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Alliant Techsystems Inc. (Edina, Minnesota) |
| INVENTOR(S) | Jason S. Tyll (Blue Point, New York); Robert J. Bakos (Wading River, New York); Florin Girlea (Flushing, New York); Ralph Woelfel (Sayville, New York); Dean Modroukas (Yonkers, New York); John I. Endos (East Hampton, New York) |
| ABSTRACT | A scramjet has a cowl, a center structure, and a plurality of wide pylons connecting the cowl to the center structure, with scramjet engines positioned between adjacent pylons. Leading surfaces of adjacent pylons converge to one another to provide side wall compression to air entering the engines. The center structure includes a fore body, a center body and an aft body that, with the pylons, define a basic structure either formed entirely from one piece or several securely connected pieces. A method of testing the scramjet projectile comprises using a gun to accelerate the scramjet projectile to the takeover velocity of the engines. |
| FILED | Monday, June 10, 2002 |
| APPL NO | 10/164718 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/374 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07053182 | Wagner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and through the State Board of Higher Education on behalf of the University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Ry Wagner (Eugene, Oregon); Karen A. Hicks (Mt. Vernon, Ohio); Michelle T. Z. Spence (Capitola, Washington); Henriette Foss (Eugene, Oregon); Xiang Liang Liu (Eugene, Oregon); Michael F. Covington (San Diego, California) |
| ABSTRACT | Nucleic acid molecules that encode plant proteins involved in photoperiodism and circadian rhythms are disclosed. These molecules may be introduced into plants in order to alter the photoperiodic and/or circadian clock-based gene expression of the plants. |
| FILED | Monday, April 18, 2005 |
| APPL NO | 11/109077 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07053200 | Zoghbi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Huda Y. Zoghbi (Houston, Texas); Hugo Bellen (Houston, Texas); Nessan Bermingham (London, United Kingdom); Bassem Hassan (Houston, Texas); Nissim Ben-arie (Mevaseret Zion, Israel) |
| ABSTRACT | Compositions and methods are disclosed for the therapeutic use of an atonal-associated nucleic acid or amino acid sequence. Also, an animal heterozygous for an atonal-associated gene inactivation is also disclosed having at least one atonal-associated nucleic acid sequence replaced by insertion of a heterologous nucleic acid sequence used to detect expression driven by an atonal-associated promoter sequence, wherein the inactivation of the atonal-associated nucleic acid sequence prevents expression of the atonal-associated gene. |
| FILED | Thursday, June 01, 2000 |
| APPL NO | 09/980381 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07054936 — Priority-based dynamic resource allocation method and apparatus for supply-demand systems
| US 07054936 | El Batt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Tamer El Batt (Woodland Hills, California); Bong Ryu (Thousand Oaks, California) |
| ABSTRACT | A computer network uplinking system, method, and computer program product are presented for allocation of network resources. A controller tier includes a controller node 100 having a processor 102, a memory 104, and a communication interface 106. Also, an uplinking tier includes uplinking nodes 108, with a processor 110, a memory 112, and a communication interface 114. The nodes 108 communicate the controller node 100 in frames. Current and next frames are represented as K and K+1. The nodes 108 request reservations from the controller node 100 based on the data each needs to transmit. The controller node 100 generates a control signal based on the reservation requests to assign slots of a information subframe of the next frame K+1 to the nodes 108 based on the priority allocated to the node 108 and the data each needs to transmit. The nodes 108 then transmit in their assigned slots. |
| FILED | Tuesday, March 12, 2002 |
| APPL NO | 10/097543 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 30, 2006.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060530.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page