FedInvent™ Patents
Patent Details for Tuesday, August 01, 2006
This page was updated on Sunday, March 26, 2023 at 08:04 PM GMT
Department of Health and Human Services (HHS)
| US 07083777 | Tzianabos et al. |
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| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Arthur O. Tzianabos (Reading, Massachusetts); Dennis L. Kasper (Charlestown, Massachusetts); Andrew B. Onderdonk (Westwood, Massachusetts); Ying Wang (Brookline, Massachusetts) |
| ABSTRACT | A pharmaceutical composition consisting of identical repeating units, each unit having a charge motif composed of a positively charged free amino moiety and a negatively charged moiety, wherein the positively charged free amino moiety and the negatively charged moiety of each charge motif are separated by at least one neutral amino acid, and wherein the positively charged free amino moiety of one of the charge motifs is separated by a distance of at least 8 amino acids from the positively charged amino moiety of another charge motif, and a pharmaceutically acceptable carrier. Said pharmaceutical composition is useful for inducing IL-2, activating T cells to produce a T helper 1 cytokine profile, suppressing IgG antibody response to specific antigen, promoting allograft survival, reducing postoperative surgical adhesion formation, and/or protecting against abscess formation associated with surgery, trauma or diseases that predispose the host to abscess formation. |
| FILED | Friday, March 31, 2000 |
| APPL NO | 09/540024 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083783 | Kaufman et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Paul L. Kaufman (Madison, Wisconsin); Xuyang Liu (Madison, Wisconsin) |
| ABSTRACT | A method for increasing outflow facility and reducing intraocular pressure from an eye of a subject having glaucoma includes the step of administering to the eye an amount of an ADP ribosyltransferase protein effective to reduce intraocular pressure and increase outflow facility. |
| FILED | Friday, February 18, 2005 |
| APPL NO | 11/060920 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083784 | Dall'Acqua et al. |
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| ASSIGNEE(S) | MedImmune, Inc. (Gaithersburg, Maryland) |
| INVENTOR(S) | William Dall'Acqua (Gaithersburg, Maryland); Leslie S. Johnson (Germantown, Maryland); Elizabeth Sally Ward (Dallas, Texas) |
| ABSTRACT | The present invention provides molecules, including IgGs, non-IgG immunoglobulin, proteins and non-protein agents, that have increased in vivo half-lives due to the presence of an IgG constant domain, or a portion thereof that binds the FcRn, having one or more amino acid modifications that increase the affinity of the constant domain or fragment for FcRn. Such proteins and molecules with increased half-lives have the advantage that smaller amounts and or less frequent dosing is required in the therapeutic, prophylactic or diagnostic use of such molecules. |
| FILED | Wednesday, December 12, 2001 |
| APPL NO | 10/020354 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083787 | Duke et al. |
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| ASSIGNEE(S) | GlobeImmune, Inc. (Louisville, Colorado); The Regents of the University of Colorado (Boulder, Colorado) |
| INVENTOR(S) | Richard C. Duke (Denver, Colorado); Donald Bellgrau (Silverthorne, Colorado); Alex Franzusoff (Denver, Colorado); Cara C. Wilson (Golden, Colorado) |
| ABSTRACT | Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by administration of a yeast vehicle and an antigen that is not complexed to the yeast vehicle is disclosed. |
| FILED | Thursday, November 15, 2001 |
| APPL NO | 09/991363 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083915 | Somlo et al. |
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| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Stefan Somlo (Westport, Connecticut); Toshio Mochizuki (Tokyo, Japan) |
| ABSTRACT | The present invention provides a purified and isolated wild type PKD2 gene, as well as mutated forms of this gene. The present invention also provides one or more single-stranded nucleic acid probes which specifically hybridize to the wild type PKD2 gene or the mutated PKD2 gene, and mixtures thereof, which may be formulated in kits, and used in the diagnosis of ADPKD associated with the mutated PKD2 gene. The present invention also provides a method for diagnosing ADPKD caused by a mutated PKD2 gene, as well as a method for treating autosomal dominant polycystic kidney disease caused by a mutated PKD2 gene. |
| FILED | Tuesday, January 02, 2001 |
| APPL NO | 09/753008 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083916 | Lester et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Henry A. Lester (South Pasadena, California); Nathan Dascal (South Pasadena, California); Nancy F. Lim (Pasadena, California); Wolfgang Schreibmayer (South Pasadena, California); Norman Davidson (Sierra Madre, California) |
| ABSTRACT | This invention provides isolated nucleic acid molecules which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel. This invention also provides a nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with the above nucleic acid molecule. This invention further provides a vector comprising the isolated nucleic acid molecules which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel. This invention provides a host vector system for the production of a polypeptide having the biological activity of KGA channel which comprises the above vector in a suitable host. This invention also provides a method for isolating from a sample a nucleic acid molecule encoding an inward rectifier, G-protein activated, potassium channel in a sample which comprises: (a) isolating the nucleic acids from the sample; (b) contacting the isolated nucleic acids with the molecule of at least 15 nucleotides capable of specifically hybridizing with the above nucleic acid molecule which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel under the conditions permitting complex formation between the nucleic acid molecule encoding an inward rectifier, G-protein activated, potassium channel and the nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with the above nucleic acid molecule which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel; (c) isolating the complex formed; and (d) separating the nucleic acid molecule encoding an inward rectifier, G-protein activated, potassium channel from the complex, thereby isolating the nucleic acid molecule encoding an inward rectifier, G-protein activated, potassium channel. |
| FILED | Monday, March 19, 2001 |
| APPL NO | 09/812074 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083917 | Barany et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Francis Barany (New York, New York); George Barany (Falcon Heights, Minnesota); Robert P. Hammer (Baton Rouge, Louisiana); Maria Kempe (Minneapolis, Minnesota); Herman Blok (Wemeldinge, Netherlands); Monib Zirvi (New York, New York) |
| ABSTRACT | The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detection phase. The ligation phase utilizes a ligation detection reaction between one oligonucleotide probe, which has a target sequence-specific portion and an addressable array-specific portion, and a second oligonucleotide probe, having a target sequence-specific portion and a detectable label. After the ligation phase, the capture phase is carried out by hybridizing the ligated oligonucleotide probes to a solid support with an array of immobilized capture oligonucleotides at least some of which are complementary to the addressable array-specific portion. Following completion of the capture phase, a detection phase is carried out to detect the labels of ligated oligonucleotide probes hybridized to the solid support. The ligation phase can be preceded by an amplification process. The present invention also relates to a kit for practicing this method, a method of forming arrays on solid supports, and the supports themselves. |
| FILED | Wednesday, September 26, 2001 |
| APPL NO | 09/963920 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083918 | Althoff et al. |
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| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Eric A. Althoff (New York, New York); Virginia W. Cornish (New York, New York) |
| ABSTRACT | A transgenic bacterial cell comprising (a) a dimeric small molecule which comprises a first moiety known to bind a first receptor domain covalently linked to a second moiety known to bind a second receptor domain; (b) nucleotide sequences which upon transcription encode i) a first fusion protein comprising the first receptor domain, and ii) a second fusion protein comprising the second receptor domain; and (c) a reporter gene wherein expression of the reporter gene is conditioned on the proximity of the first fusion protein to the second fusion protein. The cell is also adapted for use in a method for identifying a molecule that binds to a known target in a bacterial cell from a pool of candidate molecules, and a method for identifying an unknown target receptor to which a molecule is capable of binding in a bacterial cell. Also described are compounds and kits for carrying out the methods. |
| FILED | Wednesday, April 24, 2002 |
| APPL NO | 10/132039 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083923 | Keller et al. |
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| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Charles Keller (Salt Lake City, Utah); Linda Ballard (Salt Lake City, Utah); Richard Lemmons (Salt Lake City, Utah); Francis Ali-Osman (Houston, Texas) |
| ABSTRACT | A high-throughput assay for characterizing a subject's genetic makeup is disclosed. Specifically a high-throughput assay utilizing PCR is disclosed that permits the rapid and accurate characterization of a subject's inherited alleles of the polymorphic glutathione S-transferase (GST) genes GSTM1, GSTM3, GSTP1, and GSTT1. This method allows detection of the specific alleles inherited, including the gene dosage of GSTM1 and GSTT1 while not requiring restriction endonuclease digestion of the PCR products in order to detect length differences. Further, the method allows all analyses to be performed simultaneously in the same gel lane, thus further adding efficiency and cost-effectiveness. |
| FILED | Friday, July 20, 2001 |
| APPL NO | 10/296012 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083926 | Rossi et al. |
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| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | John J. Rossi (Rancho Cucamonga, California); Michaela Scherr (Oberusel, Germany); Arthur D. Riggs (La Verne, California) |
| ABSTRACT | A method for identifying sites on a target RNA which are accessible to pairing by antisense DNA, ribozymes or DNAzymes. Native or in vitro-synthesized target RNA is incubated with defined ODNs and RNase H, or with a random or semi-random ODN library and RNase H, or with defined ribozymes or DNAzymes, or with a semi-random ribozyme or DNAzyme library, in a cell extract containing endogenous RNA-binding proteins, or in a medium which mimics a cell extract due to presence of one or more RNA-binding proteins. Any antisense ODN, ribozyme or DNAzyme which is complementary to an accessisble site in the target RNA hybridizes to that site and the RNA is cleaved at that site. Reverse transcription can be used to generate a first strand DNA from the RNA cleavage product, and terminal deoxynucleotidyl transferase-dependent polymerase chain reaction (TDPCR) can be used to identify sites on target RNA to which antisense ODNs, ribozymes or DNAzymes have bound and cleavage has occurred. |
| FILED | Monday, May 12, 2003 |
| APPL NO | 10/435044 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083934 | Kawabata et al. |
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| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Hiroshi Kawabata (Los Angeles, California); H. Phillip Koeffler (Los Angeles, California) |
| ABSTRACT | The present invention provides isolated nucleic acids encoding TfR2 polypeptides, or fragments thereof, and isolated TfR2 polypeptides encoded thereby. Further provided are vectors containing the nucleic acids of the present invention, host cells transformed therewith, antisense oligonucleotides thereto and compositions containing antibodies that specifically bind to invention polypeptides. Methods of detecting TfR2 protein in a cell are also provided. |
| FILED | Tuesday, December 07, 2004 |
| APPL NO | 11/005957 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083937 | Sasisekharan et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ram Sasisekharan (Lincoln, Massachusetts); Ganesh Venkataraman (Bedford, Massachusetts); Zachary Shriver (Boston, Massachusetts); Dongfang Liu (Westborough, Massachusetts); Mallikarjun Sundaram (Ashland, Massachusetts); Yiwei Qi (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described. |
| FILED | Wednesday, September 12, 2001 |
| APPL NO | 09/951138 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07083943 — Polynucleotides related to murine anti-idiotype antibody 11D10 and methods of use thereof
| US 07083943 | Chatterjee et al. |
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| INVENTOR(S) | Malaya Chatterjee (Fort Wright, Kentucky); Kenneth A. Foon (San Carlos, California); Sunil K. Chatterjee (Fort Wright, Kentucky) |
| ABSTRACT | The present invention provides a monoclonal and-idiotype antibody 11D10 that elicits an immune response against a specific epitope of a high molecular weight mucin of human milk fat globule (HMFG) and a hybridoma that produces 11D10. The hybridoma that produces 11D10 was selected by specific procedures. 11D10 inducts an Immunological response to HMFG in mice, rabbits, monkeys and patients with advanced HMFG-associated tumors. This invention provides compositions derived from polynucleotide sequences encoding the variable light and/or variable heavy regions of monoclonal anti-idiotype antibody 11D10, as well as polypeptides encoded thereby. The invention also provides compositions which can be used in the detection or treatment of HMFG-associated tumors. |
| FILED | Thursday, December 19, 1996 |
| APPL NO | 08/836455 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083958 | Sligar et al. |
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| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen G. Sligar (Urbana, Illinois); Timothy H. Bayburt (Urbana, Illinois); Mary A. Schuler (Urbana, Illinois); Natanya R Civjan (Urbana, Illinois); Yelena V. Grinkova (Urbana, Illinois); Ilia G. Denisov (Urbana, Illinois) |
| ABSTRACT | Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. The membrane scaffold proteins (MSP) of the present invention assemble with target membrane or other hydrophobic or partially hydrophobic proteins or membrane fragments to form soluble nanoscale particles which preserve their native structure and function; they are improved over liposomes and detergent micelles. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles, which are robust in terms of integrity and maintenance of biological activity of incorporated proteins, facilitate pharmaceutical and biological research, structure/function correlation, structure determination, bioseparation, and drug discovery. |
| FILED | Wednesday, June 18, 2003 |
| APPL NO | 10/465789 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083961 | Luecke et al. |
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| ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hartmut Luecke (Irvine, California); Glen Prosise (Long Beach, California) |
| ABSTRACT | The invention provides a crystalline complex containing T. foetus IMPDH in complex with inosine monophosphate (IMP), the complex specified by disclosed atomic coordinates. Also provided are crystalline complexes of containing T. foetus IMPDH with both inosine monophosphate (IMP) and mycophenolic acid, with both xanthosine monophosphate (XMP) and mycophenolic acid, with both xanthosine monophosphate (XMP) and nicotinic adenine dinucleotide (NAD), with ribovirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide, and with both ribovirin and mycophenolic acid, each complex specified by disclosed atomic coordinates. Also provided by the invention are the atomic coordinates for these complexes. Further provided by the invention are methods for identifying modulations of IMPDH that employ the atomic coordinates of the invention. |
| FILED | Monday, September 15, 2003 |
| APPL NO | 10/663347 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083970 | Schultz et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason Chin (San Diego, California); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (La Jolla, California); Ryan Aaron Mehl (San Diego, California); Miro Pastrnak (San Diego, California); Stephen William Santoro (San Diego, California); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Friday, April 19, 2002 |
| APPL NO | 10/126931 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083979 | Williams et al. |
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| ASSIGNEE(S) | Indiana University Foundation (Bloomington, Indiana) |
| INVENTOR(S) | David A Williams (Indianapolis, Indiana); Vikram P Patel (Germantown, Maryland) |
| ABSTRACT | A method to increase the efficiency of transduction of hematopoietic and other cells by retroviruses includes infecting the cells in the presence of fibronectin or fibronectin fragments. The fibronectin and fibronectin fragments significantly enhance retroviral-mediated gene transfer into the cells, particularly hematopoietic cells including committed progenitors and primitive hematopoietic stem cells. The invention also provides improved methods for somatic gene therapy capitalizing on enhanced gene transfer, hematopoietic cellular populations, and novel constructs for enhancing retroviral-mediated DNA transfer into cells and their use. |
| FILED | Monday, September 13, 1999 |
| APPL NO | 09/394867 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083980 | Reznikoff et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William S. Reznikoff (Madison, Wisconsin); Mindy M. Steiniger-White (Madison, Wisconsin); Jeremy D. Metzler (New Franken, Wisconsin) |
| ABSTRACT | Tn5 transposase (Tnp) mutants that have higher transposase activities than the wild-type Tnp are disclosed. The Tn5 Tnp mutants differ from the wild-type Tnp at amino acid positions 54, 242, and 372 and have greater avidity than the wild-type Tnp for at least one of a wild-type Tn5 outside end sequence as defined by SEQ ID NO:3 and a modified Tn5 outside end sequence as defined by SEQ ID NO:5. Also disclosed are various systems and methods of using the Tnp mutants for in vitro or in vivo transposition. |
| FILED | Friday, April 16, 2004 |
| APPL NO | 10/826573 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084105 | Chakrabarty et al. |
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| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ananda M. Chakrabarty (Villa Park, Illinois); Tapas K. Das Gupta (River Forest, Illinois); Vas Punj (Chicago, Illinois); Olga Zaborina (Bookfield, Illinois) |
| ABSTRACT | Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death. The present inventors have found that different pathogens produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer. |
| FILED | Tuesday, January 15, 2002 |
| APPL NO | 10/047710 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Perfume compositions 512/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084111 | Haskell-Luevano |
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| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Carrie Haskell-Luevano (Archer, Florida) |
| ABSTRACT | The present invention relates to novel chimeric peptides and templates containing a combination of antagonist and agonist endogenous ligand residues. In particular, the present invention relates to novel chimeric peptides and templates thereof based upon melanocortin agonist peptides and agouti related protein (AGRP). The present invention provides multifunctional chimeric peptides having specific bioactivity at melanocortin receptors and their use as drugs to treat various diseases and conditions. |
| FILED | Monday, June 23, 2003 |
| APPL NO | 10/602394 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084239 | Wang et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Rong Fu Wang (Bethesda, Maryland); Steven Rosenberg (Potomac, Maryland) |
| ABSTRACT | The present invention discloses the identification, isolation and cloning of a gene encoding a novel cancer antigen NY ESO-1CAG-3 and peptides thereof derived from various open reading frames from the NY ESO-1 gene. The novel cancer antigen and peptides are recognized by cytotoxic T lymphocytes in an HLA restricted manner. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer. |
| FILED | Monday, September 21, 1998 |
| APPL NO | 09/529206 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084241 | Hogan et al. |
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| ASSIGNEE(S) | The CBR Institute for Biomedical Research, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Patrick G. Hogan (Cambridge, Massachusetts); Anjana Rao (Cambridge, Massachusetts); Jose Aramburu (Boston, Massachusetts) |
| ABSTRACT | Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein—protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided. |
| FILED | Thursday, January 31, 2002 |
| APPL NO | 10/066151 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084253 | Xu et al. |
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| ASSIGNEE(S) | ZymoGenetics, Inc. (Seattle, Washington) |
| INVENTOR(S) | Wenfeng Xu (Mukilteo, Washington); Scott R. Presnell (Tacoma, Washington); David P. Yee (Cambridge, Massachusetts); Donald C. Foster (Lake Forest Park, Washington) |
| ABSTRACT | The present invention relates to polynucleotide and polypeptide molecules for PAR4, a novel member of the protease-activated receptor family. The polypeptides, and polynucleotides encoding them, mediate biological responses and/or cellular signaling in response to proteases. Protease cleavage of PAR4 exposes a PAR4 extracellular amino terminal portion that serves as a ligand for the PAR4 receptor. PAR4 may be used as a target in drug screening, and further used to identify proteinaceous or non-proteinaceous PAR4 agonists and antagonists. The present invention also includes antibodies to the PAR4 polypeptides. |
| FILED | Friday, June 28, 2002 |
| APPL NO | 10/187049 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084266 | Yanagi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Masayuki Yanagi (Kanazawa, Japan); Jens Bukh (Bethesda, Maryland); Suzanne U. Emerson (Gaithersburg, Maryland); Robert H. Purcell (Gaithersburg, Maryland) |
| ABSTRACT | The present invention discloses nucleic acid sequence which encodes infectious hepatitis C virus of strain HC-J6CH, gentotype 2a, and the use of the sequence, and polypeptides encoded by all or part of the sequence, in the development of vaccines and diagnostics for HCV and in the development of screening assays for the identification of antiviral agents for HCV. |
| FILED | Sunday, February 06, 2000 |
| APPL NO | 09/980559 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084395 | Fuhrer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ionwerks, Inc. (Houston, Texas) |
| INVENTOR(S) | Katrin Fuhrer (Bern, Switzerland); Marc Gonin (Bern, Switzerland); Kent J. Gillig (College Station, Texas); Thomas F. Egan (Houston, Texas); Michael I. McCully (Houston, Texas); J. Albert Schultz (Houston, Texas) |
| ABSTRACT | Time-of-flight mass spectrometer instruments for monitoring fast processes using an interleaved timing scheme and a position sensitive detector are described. The combination of both methods is also described. |
| FILED | Monday, October 18, 2004 |
| APPL NO | 10/967715 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085348 | Kamath et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Srijit Kamath (Gainesville, Florida); Sartaj Sahni (Gainesville, Florida); Jantinder Palta (Gainesville, Florida); Sanjay Ranka (Gainesville, Florida); Jonathan G. Li (Gainesville, Florida) |
| ABSTRACT | A method of delivering radiation treatment using multi-leaf collimation includes the step of providing a radiation fluence map which includes an intensity profile. The fluence map is converted into a preliminary leaf sequence, wherein the preliminary leaf sequence minimizes machine on-time and is generated without leaf movement constraints. The leaf movement constraint is imposed on the preliminary leaf sequence. At least one constraint elimination algorithm is then applied, the algorithm adjusting the preliminary leaf sequence to minimize violations of the constraint while providing the desired fluence map and minimized radiation on-time. The method can be applied to SMLC and DLMC systems, and can include adjustment for the tongue-and-groove effect. |
| FILED | Monday, December 15, 2003 |
| APPL NO | 10/736023 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07082823 | Shipman et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | John M. Shipman (Albuquerque, New Mexico); Eric T. Judkins (Albuquerque, New Mexico); J. Rick Martin (Rio Rancho, New Mexico); Daniel E. Burkholder (Maurepas, Louisiana) |
| ABSTRACT | A system for precisely measuring muzzle exit velocity of a “muzzle loaded” mortar projectile fired from a mortar tube using two back-biased Hall effect sensors for projectile gas ring channel detection. The system includes a back-biased Hall effect sensor block, a digital resolver electronic circuit and a computer software interface. The back-biased Hall effect sensors are located in a calibrated sensor block attached to a mortar tube. As the projectile metal casing passes a face of the sensors, the sensors trigger and release, providing two electronic pulses. The pulse edges are captured in the resolver electronics, containing a discriminator circuit for filtering all input pulses to distinguish between a projectile loading event and a projectile firing event. Once a valid firing event is detected, an output of precision timers is presented serially to a computer where it is processed and displayed by a computer software interface. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/035656 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/167 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083140 | Dooley |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert B. Dooley (Canton, Massachusetts) |
| ABSTRACT | A method and structure for a full-bore artillery projectile fin deployment device comprising a projectile stabilization fin comprising an aperture and a movable pawl; a rod comprising a head portion and a shaft portion terminating with a beveled tip configured for engaging the pawl; a tailboom configured for housing the fin, wherein the tailboom comprises a hollow bore configured for receiving the rod; a pin slotted through the aperture and attached to the tailboom; and a bias member adjacent to the head portion of the rod. The rod is slotted to simultaneously engage a plurality of fins. The tailboom comprises a forward end and a rearward end and a slot configured for permitting the fin to articulate out of the tailboom, and wherein the tailboom connects to a projectile. Additionally, the power source for the device is the naturally occurring launch accelerations. |
| FILED | Tuesday, September 14, 2004 |
| APPL NO | 10/939418 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeronautics and astronautics 244/3.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083383 | Loftus et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Robert T. Loftus (Gilbert, Arizona); Michael J. McNulty (Scottsdale, Arizona); Keith B. Smith (Gilbert, Arizona) |
| ABSTRACT | A trim tab assembly for a helicopter rotor blade includes a plurality of metal panels that are secured to the trailing edge of a composite material helicopter blade. Each of the metal panels can be bent relative to the rotor blade to tune the aerodynamic properties of the rotor blade. |
| FILED | Monday, April 26, 2004 |
| APPL NO | 10/832149 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/132.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083388 | Parisi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Francis B. Parisi (West Suffield, Connecticut); Stephen M. Glinn (Simsbury, Connecticut); Carl W. Mercier (Willington, Connecticut) |
| ABSTRACT | A method of forming a blade comprising the steps of forging a part comprising a suction side, a pressure side, and a dividing portion of material greater than a portion of material to be sacrificed between the suction side and the pressure side, splitting the part through the dividing portion of material to form a suction side inner surface and a pressure side inner surface, and joining the suction side inner surface and the pressure side inner surface to form the blade. |
| FILED | Thursday, April 29, 2004 |
| APPL NO | 10/835035 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/223.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083747 | Hampden-Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark J Hampden-Smith (Albuquerque, New Mexico); Toivo T Kodas (Albuquerque, New Mexico); Quint H Powell (Albuquerque, New Mexico); Daniel J Skamser (Albuquerque, New Mexico); James Caruso (Albuquerque, New Mexico); Clive D Chandler (Portland, Oregon) |
| ABSTRACT | Provided is an aerosol method, and accompanying apparatus, for preparing powdered products of a variety of materials involving the use of an ultrasonic aerosol generator (106) including a plurality of ultrasonic transducers (120) underlying and ultrasonically energizing a reservoir of liquid feed (102) which forms droplets of the aerosol. Carrier gas (104) is delivered to different portions of the reservoir by a plurality of gas delivery ports (136) delivering gas from a gas delivery system. The aerosol is pyrolyzed to form particles, which are then cooled and collected. The invention also provides powders that include coated particles made by the method and devices made using the coated particles. |
| FILED | Monday, November 01, 2004 |
| APPL NO | 10/904257 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083945 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Gang Chen (Austin, Texas); Andrew Hayhurst (Austin, Texas); Jeffrey G. Thomas (Bellevue, Washington); Brent L. Iverson (Austin, Texas); George Georgiou (Austin, Texas) |
| ABSTRACT | The invention overcomes the deficiencies of the prior art by providing a rapid approach for isolating binding proteins capable of binding small molecules and peptides via “display-less” library screening. In the technique, libraries of candidate binding proteins, such as antibody sequences, are expressed in soluble form in the periplasmic space of gram negative bacteria, such as Escherichia coli, and are mixed with a labeled ligand. In clones expressing recombinant polypeptides with affinity for the ligand, the concentration of the labeled ligand bound to the binding protein is increased and allows the cells to be isolated from the rest of the library. Where fluorescent labeling of the target ligand is used, cells may be isolated by fluorescence activated cell sorting (FACS). The approach is more rapid than prior art methods and avoids problems associated with the surface-expression of ligand fusion proteins employed with phage display. |
| FILED | Friday, October 27, 2000 |
| APPL NO | 09/699023 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083959 | Dintzis et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Howard M. Dintzis (Baltimore, Maryland); Renee Z. Dintzis (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to a method of specifically suppressing an undesired immune response in a mammal suffering from such a response. The method comprises: i) preparing a construct comprising at least one discrete antigenically recognizable moiety corresponding to an antigenic determinant of an antigen causing the undesired immune response bound to a pharmacologically acceptable carrier wherein the number of the moieties bound to the carrier and the spacing of the moieties on the carrier are such that the construct does not elicit an immune response to the moieties but does directly compete with the antigen for receptors on an immunocompetent cell that recognizes the determinant, and thereby the construct specifically suppresses the undesired immune response; and ii) administering the construct to the mammal in an amount such that suppression of the undesired immune response is effected. The invention further relates to constructs suitable for use in the above method and to methods of making same. |
| FILED | Tuesday, January 09, 2001 |
| APPL NO | 09/757774 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083970 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason Chin (San Diego, California); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (La Jolla, California); Ryan Aaron Mehl (San Diego, California); Miro Pastrnak (San Diego, California); Stephen William Santoro (San Diego, California); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Friday, April 19, 2002 |
| APPL NO | 10/126931 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084040 | Gambin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corp. (Los Angeles, California) |
| INVENTOR(S) | Vincent Gambin (Torrance, California); Donald J. Sawdai (Redondo Beach, California) |
| ABSTRACT | Formation of a regrowth layer of a Group III–V semiconductor material is facilitated by prior formation of an intermediate layer, selected primarily for its smooth morphology properties. The intermediate layer is formed over an underlying substrate and over a dielectric layer formed over portions of the substrate. The intermediate layer maintains the monocrystalline properties of the underlying substrate in regions other than those covered by the dielectric layer, and improves the electrical and morphology properties of the regrowth layer formed over the intermediate layer. |
| FILED | Friday, April 23, 2004 |
| APPL NO | 10/830729 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/312 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084132 | Hartell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Mark G. Hartell (Laurel, Maryland); Apurba K. Bhattacharjee (Silver Spring, Maryland); Rickey P. Hicks (Woodbridge, Virginia); John E. VanHamont (Fort Meade, Maryland); Wilbur K. Milhous (Germantown, Maryland) |
| ABSTRACT | A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic decomposition rendering it stable in solution. Artelinic acid and cyclodextrin are placed into contact with one another to yield a 2:1 molecular species. Artesunic acid and cyclodextrin yield a 1:1 molecular species. The complexed cyclodextrin artemisinin formulation is effective for the treatment of malaria and is stable in solution for long periods of time. |
| FILED | Monday, April 25, 2005 |
| APPL NO | 11/113546 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/58 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084405 | Malyutenko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Volodymyr K. Malyutenko (Kiev, Ukraine); James R. Kircher (Mendon, New York); Robert L. Murrer, Jr. (Sewickley, Pennsylvania); Donald R. Snyder, III (Crestview, Florida); Oleg Y. Malyutenko (Kiev, Ukraine); Vyacheslav V. Bogatyrenko (Kiev, Ukraine) |
| ABSTRACT | A high-speed, high-resolution, broadband dynamic infrared scene generator based on semiconductor transducer conversion of visible spectrum scene images into infrared spectrum images. Wavelength conversion is accomplished in the semiconductor material through absorption of visible spectrum energy by valence electrons in a subsurface layer of the semiconductor material and photogeneration by valence band to conduction band electron transfer occurring within about one diffusion length of the semiconductor material surface. The semiconductor material used, for example Germanium or Silicon provides a band gap energy value that is smaller than the quantum energy level of the optical emission. Temperature of the semiconductor material may be maintained at a selected level above or below that of the infrared scene. Infrared images of higher frequency content than are achievable with conventional thermal heating infrared converters are accomplished. The invention thus includes down conversion of visible generated light in order to develop a semiconductor pixel-less Dynamic Infrared Scene Projector capable of simulating high-speed broadband IR scenery. |
| FILED | Friday, May 07, 2004 |
| APPL NO | 10/845609 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/370.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084409 | Danielson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | PhotoSense, LLC (Boulder, Colorado) |
| INVENTOR(S) | J. D. Sheldon Danielson (Boulder, Colorado) |
| ABSTRACT | An apparatus for measuring emission time delay during irradiation of targeted samples by utilizing digital signal processing to determine the emission phase shift caused by the sample is disclosed. The apparatus includes a source of electromagnetic radiation adapted to irradiate a target sample. A mechanism generates first and second digital input signals of known frequencies with a known phase relationship, and a device then converts the first and second digital input signals to analog sinusoidal signals. An element is provided to direct the first input signal to the electromagnetic radiation source to modulate the source by the frequency thereof to irradiate the target sample and generate a target sample emission. A device detects the target sample emission and produces a corresponding first output signal having a phase shift relative to the phase of the first input signal, the phase shift being caused by the irradiation time delay in the sample. A member produces a known phase shift in the second input signal to create a second output signal. A mechanism is then provided for converting each of the first and second analog output signals to digital signals. A mixer receives the first and second digital output signals and compares the signal phase relationship therebetween to produce a signal indicative of the change in phase relationship between the first and second output signals caused by the target sample emission. Finally, a feedback arrangement alters the phase of the second input signal based on the mixer signal to ultimately place the first and second output signals in quadrature. Mechanisms for enhancing this phase comparison and adjustment technique are also disclosed. |
| FILED | Tuesday, August 22, 2000 |
| APPL NO | 09/642596 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Radiant energy 250/458.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084726 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | TiNi Alloy Company (San Leandro, California) |
| INVENTOR(S) | Vikas Gupta (San Leandro, California); Valery Martynov (San Francisco, California) |
| ABSTRACT | A microrelay device formed on a silicon substrate wafer for use in opening and closing a current path in a circuit. A pair of electrically conducting latching beams are attached at their proximal ends to terminals on the substrate. Proximal ends of the beams have complementary shapes which releasably fit together to latch the beams and close the circuit. A pair of shape memory alloy actuators are selectively operated to change shapes which bend one of the beams in a direction which latches the distal ends, or bend the other beam to release the distal ends and open the circuit. The microrelay is bistable in its two positions, and power to the actuators is applied only for switching it open or closed. |
| FILED | Monday, September 15, 2003 |
| APPL NO | 10/661035 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Magnetically operated switches, magnets, and electromagnets 335/78 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084835 | McCormick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Donald M. McCormick (Mt. Pleasant, South Carolina); Ken A. Crawley (St. George, South Carolina); Dean A. Glace (Summerville, South Carolina) |
| ABSTRACT | A compact antenna assembly which includes a lower member having a mast that is an elongated configuration terminating at an upper end and a lower end. The mast can be located at the center of an upper member. The upper member includes an emitter, having a perimeter, a top end, and a bottom end. The upper end of the mast is electrically connected to the perimeter near the top end. Furthermore, a collector with a centrally disposed opening can be placed in a horizontal plane which positions the collector orthogonally in space with respect to the mast so that the collector is electrically insulated from the emitter and the mast. The lower end of the mast is centered at the centrally disposed opening of the collector and extends perpendicularly to the plane of the collector. |
| FILED | Friday, December 17, 2004 |
| APPL NO | 11/015267 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/890 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084867 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Stephen S. Ho (Cambridge, Massachusetts); Sanjay Sarma (Belmont, Massachusetts) |
| ABSTRACT | A method and system are provided for controlling the simulated interfacing of a controlled first body, for example a tool, with a second body while providing haptic feedback to a user on such interfacing. Selected representations of the first and second bodies are stored in a memory of a processing apparatus and are used by such apparatus to control simulated movement of the first body relative to the second body in response to a user controlled haptic interface device. Collisions between the first and second body are detected, including the position on each body of each collision, the direction of the collision and the force of the collision, and this information is converted for each collision into a force vector on the first body which is fed back as a corresponding force vector to the interface device, and thus to the user. A feature of the invention is storing a point cloud representation of at least one of the bodies, which point cloud representation is utilized in the simulations. The representations may also be an implicit equation representation, a binary space tree partition representation or the like. A niceness factor may also be utilized in determining force feedback as may a guide zone around at least a portion of one of the bodies which, for example, may be utilized to provide a snap-fit. Other features are also provided. |
| FILED | Friday, March 31, 2000 |
| APPL NO | 09/542942 |
| ART UNIT | 2629 — Semiconductors/Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084987 | Kreuzer |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ASML Holdings N.V. (Veldhoven, Netherlands) |
| INVENTOR(S) | Justin L. Kreuzer (Trumbull, Connecticut) |
| ABSTRACT | Coherent illumination is used to illuminate a symmetrical alignment mark with an image rotation interferometer producing two images of the alignment mark, rotating the images 1800 with respect to each other, and recombining the images interferometrically. The recombined images interfere constructively or destructively, in an amplitude and or polarization sense depending upon the method of recombination, when the alignment sensor is located at the center of the alignment mark. The rotation interferometer is preferably a solid glass assembly made of a plurality of prisms. A detector extracts the alignment information from the image rotation interferometer. The resulting center of the alignment mark is accurately determined. A relatively large number of different alignment mark patterns may be utilized, as long as the alignment mark patterns exhibit one hundred and eighty degree symmetry. Parallel lines, a grid pattern, or a checkerboard grating may be used. The alignment sensor may be applied to a scanning photolithographic system providing sinusoidal alignment signals. The alignment system is particularly applicable to photolithography as used in semiconductor manufacturing. |
| FILED | Thursday, October 07, 2004 |
| APPL NO | 10/959511 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/508 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085236 | Oldak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts, Amherst (Amherst, Massachusetts) |
| INVENTOR(S) | Salomon Oldak (Los Angeles, California); Wei-Bo Gong (Amherst, Massachusetts); Christopher V. Hollot (Easthampton, Massachusetts); Don Towsley (Amherst, Massachusetts); Vishal Misra (New York, New York); Yossi Chait (Longmeadow, Massachusetts) |
| ABSTRACT | A method of regulating queuing delay in a network routing device independent of TCP loading is provided including receiving data packets, monitoring the data packets using token buckets and a Proportional and Integral (P+I) Active Queue Management (AQM) scheme, marking selected data packets falling within a profile, and adjusting flow preference of the monitored packets. |
| FILED | Monday, May 20, 2002 |
| APPL NO | 10/151638 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085242 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Telcordia Technologies, Inc. (Piscataway, New Jersey) |
| INVENTOR(S) | Kevin H. Liu (Ocean Township, New Jersey) |
| ABSTRACT | A virtual IP topology in an IRW network is dynamically migrated from a current topology to a new topology while minimizing end user impact by maximizing network connectivity and by minimizing impact on heavier traffic communications. The virtual IP connections that must be added and removed to migrate from the old to the new topology are first determined. Next, two connections are selected and removed from the network with the objective of maintaining network connectivity and minimizing impact on heavier traffic communications. All virtual connections that satisfy resource constraints are then selected and added to the network. Next, at most one virtual connection is selected and removed from the network, the selected connection being the least loaded connection that leaves the network in a connected state. Finally, virtual connections are continuously added and removed until the network is completely migrated to the new topology. In a second embodiment, butterfly switching is initially performed. |
| FILED | Friday, March 22, 2002 |
| APPL NO | 10/104241 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/254 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085304 | Vetrovec |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jan Vetrovec (Thousand Oaks, California) |
| ABSTRACT | Methods, systems and apparatus are provided for amplifying a source light in a solid state laser. An amplifier module for the solid state laser suitably includes a disk having two substantially parallel surfaces and an optical gain material. A number of diode bars are arranged about the perimeter of the disk and configured to provide optical pump radiation to the laser gain material in the disk. Each of the plurality of diode bars is spatially aligned with the disk in such a manner as to produce substantially uniform gain across the optical gain material. The fast axes of the diode bars maybe aligned to be parallel or orthogonal to the parallel surfaces of the disk, for example. |
| FILED | Monday, May 19, 2003 |
| APPL NO | 10/441373 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085351 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Jianping Lu (Chapel Hill, North Carolina); Otto Zhou (Chapel Hill, North Carolina); Yuan Cheng (Chapel Hill, North Carolina) |
| ABSTRACT | An x-ray generating device includes a field emission cathode formed at least partially from a nanostructure-containing material having an emitted electron current density of at least 4 A/cm2. High energy conversion efficiency and compact design are achieved due to easy focusing of cold cathode emitted electrons and dramatic reduction of heating at the anode. In addition, by pulsing the field between the cathode and the gate or anode and focusing the electron beams at different anode materials, pulsed x-ray radiation with varying energy can be generated from a single device. Methods and apparatus for independent control of electron emission current and x-ray energy in x-ray tubes are also provided. The independent control can be accomplished by adjusting the distance between the cathode and anode. The independent control can also be accomplished by adjusting the temperature of the cathode. The independent control can also be accomplished by optical excitation of the cathode. The cathode can include field emissive materials such as carbon nanotubes. |
| FILED | Wednesday, February 05, 2003 |
| APPL NO | 10/358160 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/122 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085406 | Alyassin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Abdalmajeid Musa Alyassin (Niskayuna, New York) |
| ABSTRACT | A method and system are provided for generating transfer functions for use in volume rendering of three-dimensional data of an object volume. The method comprises obtaining the three-dimensional data of the object volume, evaluating selected characteristics for a plurality of samples of the three-dimensional data and computing a transfer function range for volume rendering the three-dimensional data based on the selected characteristics. The system comprises an imaging device and an image processing device. The image processing device is adapted to generate at least one three-dimensional image data set of the object volume based on obtained image data and is further adapted to compute a transfer function range for use in volume rendering. |
| FILED | Friday, July 27, 2001 |
| APPL NO | 09/682157 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085409 | Sawhney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sarnoff Corporation (Princeton, New Jersey) |
| INVENTOR(S) | Harpreet Singh Sawhney (West Windsor, New Jersey); Hai Tao (Lawrenceville, New Jersey); Rakesh Kumar (Monmouth Junction, New Jersey); Keith Hanna (Princeton, New Jersey) |
| ABSTRACT | An image-based tele-presence system forward warps video images selected from a plurality fixed imagers using local depth maps and merges the warped images to form high quality images that appear as seen from a virtual position. At least two images, from the images produced by the imagers, are selected for creating a virtual image. Depth maps are generated corresponding to each of the selected images. Selected images are warped to the virtual viewpoint using warp parameters calculated using corresponding depth maps. Finally the warped images are merged to create the high quality virtual image as seen from the selected viewpoint. The system employs a video blanket of imagers, which helps both optimize the number of imagers and attain higher resolution. In an exemplary video blanket, cameras are deployed in a geometric pattern on a surface. |
| FILED | Tuesday, October 16, 2001 |
| APPL NO | 09/978158 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085541 | Redi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | BBNT Solutions LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | Jason Keith Redi (Belmont, Massachusetts); Keith William Manning (Arlington, Massachusetts); Mitchell Paul Tasman (Boston, Massachusetts) |
| ABSTRACT | A node (105-1) determines a power level for transmitting to a neighboring node (105-2) in a wireless network (100). The node (105-1) receives one or more messages indicating a location of the neighboring node and a type of directional antenna of the neighboring node (105-2) that transmitted the one or more messages. The node (105-1) determines the power level for transmitting to the neighboring node (105-2) based on the location of the neighboring node (105-2) and the type of the directional antenna. |
| FILED | Friday, January 31, 2003 |
| APPL NO | 10/355311 |
| ART UNIT | 2682 — Optics |
| CURRENT CPC | Telecommunications 455/69 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07086040 | Joisha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Pramod G. Joisha (Evanston, Illinois); Prithviraj Banerjee (Glenview, Illinois); Nagaraj Shenoy (Karnataka, India) |
| ABSTRACT | A method for inferring the shape and dimension of arrays for high-level, array-based languages such as MATLAB is presented. The method uses the algebraic properties that underlie MATLAB's shape semantics and infers the shape that the program expression assumes. In one embodiment, a shape-tuple of the result of a program expression is inferred by creating a shape-tuple expression comprising the shape-tuples of the operands and the shape-tuple operator. |
| FILED | Tuesday, January 30, 2001 |
| APPL NO | 09/773211 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/137 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US H2163 | Mulhern |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis M. Mulhern (Riverton, New Jersey) |
| ABSTRACT | A floating object is attached to a shipboard hoisting crane through its attachment device under high seawave conditions, by maintaining alignment of the crane attachment device under maneuvering thrust control with a location on the floating object during lowering of the attachment device onto the floating object. Such maneuvering thrust control is established by thrust jets emitted from the attachment device under control of optical scanning detection cells mounted on the attachment device for reception of a reception location indicating beam emitted from the floating object. |
| FILED | Thursday, December 18, 2003 |
| APPL NO | 10/738077 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Handling: Hand and hoist-line implements 294/66.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07082826 | Robertson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Eric P. Robertson (Idaho Falls, Idaho) |
| ABSTRACT | A gas flow rate meter includes an upstream line and two chambers having substantially equal, fixed volumes. An adjustable valve may direct the gas flow through the upstream line to either of the two chambers. A pressure monitoring device may be configured to prompt valve adjustments, directing the gas flow to an alternate chamber each time a pre-set pressure in the upstream line is reached. A method of measuring the gas flow rate measures the time required for the pressure in the upstream line to reach the pre-set pressure. The volume of the chamber and upstream line are known and fixed, thus the time required for the increase in pressure may be used to determine the flow rate of the gas. Another method of measuring the gas flow rate uses two pressure measurements of a fixed volume, taken at different times, to determine the flow rate of the gas. |
| FILED | Thursday, October 14, 2004 |
| APPL NO | 10/966632 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07082850 | Hughes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Eaton Corporation (Cleveland, Ohio) |
| INVENTOR(S) | Douglas A. Hughes (Wixom, Michigan) |
| ABSTRACT | A powertrain system is provided that includes a first prime mover and change-gear transmission having a first input shaft and a second input shaft. A twin clutch is disposed between the first prime mover and the transmission. The twin clutch includes a first main clutch positioned between the first prime mover and the first input shaft and a second main clutch positioned between the first prime mover and the second input shaft. The powertrain system also includes a second prime mover operably connected to one of the first and second input shafts. |
| FILED | Tuesday, December 30, 2003 |
| APPL NO | 10/747993 |
| ART UNIT | 3681 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Machine element or mechanism 074/329 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083672 | Wagh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dentsply International, Inc. (York, Pennsylvania); University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Arun S. Wagh (Naperville, Illinois); Carolyn Primus (Bradenton, Florida) |
| ABSTRACT | The present invention is directed to magnesium phosphate ceramics and their methods of manufacture. The composition of the invention is produced by combining a mixture of a substantially dry powder component with a liquid component. The substantially dry powder component comprises a sparsely soluble oxide powder, an alkali metal phosphate powder, a sparsely soluble silicate powder, with the balance of the substantially dry powder component comprising at least one powder selected from the group consisting of bioactive powders, biocompatible powders, fluorescent powders, fluoride releasing powders, and radiopaque powders. The liquid component comprises a pH modifying agent, a monovalent alkali metal phosphate in aqueous solution, the balance of the liquid component being water. The use of calcined magnesium oxide as the oxide powder and hydroxylapatite as the bioactive powder produces a self-setting ceramic that is particularly suited for use in dental and orthopedic applications. |
| FILED | Friday, August 06, 2004 |
| APPL NO | 10/913185 |
| ART UNIT | 1755 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Compositions: Coating or plastic 16/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083708 | Chlistunoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
| INVENTOR(S) | Jerzy B. Chlistunoff (Los Alamos, New Mexico); Ludwig Lipp (Brookfield, Connecticut); Shimshon Gottesfeld (Niskayuna, New York) |
| ABSTRACT | Oxygen-consuming zero gap chlor-alkali cell was configured to minimize peroxide formation. The cell included an ion-exchange membrane that divided the cell into an anode chamber including an anode and a cathode chamber including an oxygen gas diffusion cathode. The cathode included a single-piece of electrically conducting graphitized carbon cloth. Catalyst and polytetrafluoroethylene were attached to only one side of the cloth. When the cathode was positioned against the cation exchange membrane with the catalyst side away from the membrane, electrolysis of sodium chloride to chlorine and caustic (sodium hydroxide) proceeded with minimal peroxide formation. |
| FILED | Thursday, July 31, 2003 |
| APPL NO | 10/631073 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/252 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083765 | Ott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Los Alamos, New Mexico) |
| INVENTOR(S) | Kevin C. Ott (Los Alamos, New Mexico); Noline C. Clark (Jemez Springs, New Mexico); Mark T. Paffett (Los Alamos, New Mexico) |
| ABSTRACT | The present invention provides a process for catalytically reducing nitrogen oxides in an exhaust gas stream containing nitrogen oxides and a reductant material by contacting the gas stream under conditions effective to catalytically reduce the nitrogen oxides with a catalyst comprising a aluminum-silicate type material and a minor amount of a metal, the catalyst characterized as having sufficient catalytic activity so as to reduce the nitrogen oxides by at least 60 percent under temperatures within the range of from about 200° C. to about 400° C. |
| FILED | Tuesday, April 06, 2004 |
| APPL NO | 10/819634 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083951 | Nasarabadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shanavaz Nasarabadi (Livermore, California); Richard G. Langlois (Livermore, California); Kodumudi S. Venkateswaran (Livermore, California) |
| ABSTRACT | Disclosed herein are two methods for rapid multiplex analysis to determine the presence and identity of target DNA sequences within a DNA sample. Both methods use reporting DNA sequences, e.g., modified conventional Taqman® probes, to combine multiplex PCR amplification with microsphere-based hybridization using flow cytometry means of detection. Real-time PCR detection can also be incorporated. The first method uses a cyanine dye, such as, Cy3™, as the reporter linked to the 5′ end of a reporting DNA sequence. The second method positions a reporter dye, e.g., FAM, on the 3′ end of the reporting DNA sequence and a quencher dye, e.g., TAMRA, on the 5′ end. |
| FILED | Thursday, February 14, 2002 |
| APPL NO | 10/077321 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083960 | Donnelly |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cognis Corporation (Ambler, Pennsylvania) |
| INVENTOR(S) | Mark Donnelly (Warrenville, Illinois) |
| ABSTRACT | The present invention provides soluble cytochrome p450 reductase (CPR) proteins from Candida sp. having an altered N-terminal region which results in reduced hydrophobicity of the N-terminal region. Also provided are host cells comprising the subject soluble CPR proteins. In addition, the present invention provides nucleotide and corresponding amino acid sequences for soluble CPR proteins and vectors comprising the nucleotide sequences. Methods for producing a soluble CPR, for increasing production of a dicarboxylic acid, and for detecting a cytochrome P450 are also provided. |
| FILED | Tuesday, October 15, 2002 |
| APPL NO | 10/272017 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083970 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason Chin (San Diego, California); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (La Jolla, California); Ryan Aaron Mehl (San Diego, California); Miro Pastrnak (San Diego, California); Stephen William Santoro (San Diego, California); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Friday, April 19, 2002 |
| APPL NO | 10/126931 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084366 | Hosking et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | F. Michael Hosking (Albuquerque, New Mexico); Aaron C. Hall (Albuquerque, New Mexico); Richard C. Givler (Albuquerque, New Mexico); Charles A. Walker (Albuquerque, New Mexico) |
| ABSTRACT | A method for making a braze joint across a discontinuity in a work piece using alternating current. A filler metal is pre-placed at a location sufficiently close to the discontinuity such that, when an alternating current is applied across a work piece to heat the work piece and melt the filler metal, the filler metal is drawn into the discontinuity. The alternating current is maintained for a set residence time, generally less than 10 seconds and more particularly less than 3 seconds. The alternating current is then altered, generally by reducing the current and/or voltage such that the filler metal can solidify to form a braze joint of desired quality and thickness. |
| FILED | Tuesday, February 10, 2004 |
| APPL NO | 10/777666 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric heating 219/76.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084407 | Ji et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qing Ji (Berkeley, California); Keith Standiford (Carmel, California); Tsu-Jae King (Fremont, California); Ka-Ngo Leung (Hercules, California) |
| ABSTRACT | An extractor system for a plasma ion source has a single (first) electrode with one or more apertures, or a pair of spaced electrodes, a first or plasma forming electrode and a second or extraction electrode, with one or more aligned apertures. The aperture(s) in the first electrode (or the second electrode or both) have a counterbore on the downstream side (i.e. away from the plasma ion source or facing the second electrode). The counterbored extraction system reduces aberrations and improves focusing. The invention also includes an ion source with the counterbored extraction system, and a method of improving focusing in an extraction system by providing a counterbore. |
| FILED | Thursday, February 13, 2003 |
| APPL NO | 10/367664 |
| ART UNIT | 2821 — Optics |
| CURRENT CPC | Radiant energy 250/423.F00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085305 | Richardson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | John G. Richardson (Idaho Falls, Idaho) |
| ABSTRACT | Methods of operation of an induction melter include providing material within a cooled crucible proximate an inductor. A desired electromagnetic flux skin depth for heating the material within the crucible may be selected, and a frequency of an alternating current for energizing the inductor and for producing the desired skin depth may be selected. The alternating current frequency may be adjusted after energizing the inductor to maintain the desired electromagnetic flux skin depth. The desired skin depth may be substantially maintained as the temperature of the material varies. An induction heating apparatus includes a sensor configured to detect changes in at least one physical characteristic of a material to be heated in a crucible, and a controller configured for selectively varying a frequency of an alternating current for energizing an inductor at least partially in response to changes in the physical characteristic to be detected by the sensor. |
| FILED | Wednesday, August 25, 2004 |
| APPL NO | 10/926900 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Industrial electric heating furnaces 373/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085653 | Terwilliger |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Thomas C. Terwilliger (Santa Fe, New Mexico) |
| ABSTRACT | Structure factor bias in an electron density map for an unknown crystallographic structure is minimized by using information in a first electron density map to elicit expected structure factor information. Observed structure factor amplitudes are combined with a starting set of crystallographic phases to form a first set of structure factors. A first electron density map is then derived and features of the first electron density map are identified to obtain expected distributions of electron density. Crystallographic phase probability distributions are established for possible crystallographic phases of reflection k, and the process is repeated as k is indexed through all of the plurality of reflections. An updated electron density map is derived from the crystallographic phase probability distributions for each one of the reflections. The entire process is then iterated to obtain a final set of crystallographic phases with minimum bias from known electron density maps. |
| FILED | Wednesday, December 12, 2001 |
| APPL NO | 10/017643 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085694 | Xavier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Patrick G. Xavier (Albuquerque, New Mexico); Eric J. Gottlieb (Corrales, New Mexico); Michael J. McDonald (Albuquerque, New Mexico); Fred J. Oppel, III (Albuquerque, New Mexico) |
| ABSTRACT | A method and apparatus accommodate interaction phenomenon in a data-flow-based simulation of a system of elements, by establishing meta-modules to simulate system elements and by establishing world modules associated with interaction phenomena. World modules are associated with proxy modules from a group of meta-modules associated with one of the interaction phenomenon. The world modules include a communication world, a sensor world, a mobility world, and a contact world. World modules can be further associated with other world modules if necessary. Interaction phenomenon are simulated in corresponding world modules by accessing member functions in the associated group of proxy modules. Proxy modules can be dynamically allocated at a desired point in the simulation to accommodate the addition of elements in the system of elements such as a system of robots, a system of communication terminals, or a system of vehicles, being simulated. |
| FILED | Monday, October 22, 2001 |
| APPL NO | 10/037096 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085701 | Rich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Marvin J. Rich (Poughkeepsie, New York); Ashutosh Misra (Bangalore, India) |
| ABSTRACT | A method and system select delay values from a VHDL standard delay file that correspond to an instance of a logic gate in a logic model. Then the system collects all the delay values of the selected instance and builds super generics for the rise-time and the fall-time of the selected instance. Then, the system repeats this process for every delay value in the standard delay file (310) that correspond to every instance of every logic gate in the logic model. The system then outputs a reduced size standard delay file (314) containing the super generics for every instance of every logic gate in the logic model. |
| FILED | Wednesday, January 02, 2002 |
| APPL NO | 10/038311 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07083547 | LaStayo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents (Phoenix, Arizona); Eccentron, LLC (Denver, Colorado) |
| INVENTOR(S) | Paul LaStayo (Salt Lake City, Utah); Stan Lindstedt (Flagstaff, Arizona); Hans Hoppeler (Bolligen, Switzerland); Henry Madden (Boulder, Colorado); Daniel A. Estoque (Boulder, Colorado); William B. Stephens (Boulder, Colorado); Gregory D. Volan (Longmont, Colorado) |
| ABSTRACT | A method and apparatus for providing speed controlled eccentric exercise which include an exercise apparatus having an engagement member for engaging a user's body where the engagement member is moveable in opposite directions, means for enabling the engagement member to exert a force in a first direction at a predetermined speed, means for detecting change in the predetermined speed or pressure of the force after a user applies a force to the engagement means in a direction opposite the first force, and means for adjusting the apparatus supplied force and user supplied forces to equal one another or to maintain the predetermined speed. |
| FILED | Wednesday, August 27, 2003 |
| APPL NO | 10/650455 |
| ART UNIT | 3764 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Exercise devices 482/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083925 | Schnabel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert D. Schnabel (Columbia, Missouri); James N. Derr (College Station, Texas) |
| ABSTRACT | A method for determining parentage of North American bison or domestic cattle offspring. In the method an offspring is tested to determine the alleles present in that offspring for selected loci. A pool of potential parents is also tested to determine which alleles of these loci are present in each parent. The likelihood that any potential parent is the parent of the offspring may then be determined by looking for the presence or absence of an allele in the offspring that is present in the parent or by some comparable method. The method may also be used to exclude all potential parents in a pool. Sixteen loci which may be used in such an analysis are BM1225, BM1706, BM17132, BM1905, BM2113, BM4440, BM720, BMS1862, BMS410, BMS510, BMS527, RM372, BMS1172, BMS2639, BM3628 and BMS2325. The method used to select these loci is also disclosed. |
| FILED | Monday, January 13, 2003 |
| APPL NO | 10/340939 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083958 | Sligar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen G. Sligar (Urbana, Illinois); Timothy H. Bayburt (Urbana, Illinois); Mary A. Schuler (Urbana, Illinois); Natanya R Civjan (Urbana, Illinois); Yelena V. Grinkova (Urbana, Illinois); Ilia G. Denisov (Urbana, Illinois) |
| ABSTRACT | Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. The membrane scaffold proteins (MSP) of the present invention assemble with target membrane or other hydrophobic or partially hydrophobic proteins or membrane fragments to form soluble nanoscale particles which preserve their native structure and function; they are improved over liposomes and detergent micelles. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles, which are robust in terms of integrity and maintenance of biological activity of incorporated proteins, facilitate pharmaceutical and biological research, structure/function correlation, structure determination, bioseparation, and drug discovery. |
| FILED | Wednesday, June 18, 2003 |
| APPL NO | 10/465789 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084208 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gang Sun (Davis, California); Yuyu Sun (Davis, California) |
| ABSTRACT | The present invention provides heterocyclic vinylic compounds that can be used to form biocidal polymers. The polymers thus generated can used alone or can be grafted onto textiles, fabrics and polymers. The polymers are readily converted to N-halamine structures on exposure to a halogen source such as commercially available chlorine bleach. The N-halamine derivatives exhibit potent antibacterial properties against microorganisms and these properties are durable and regenerable. |
| FILED | Tuesday, May 06, 2003 |
| APPL NO | 10/431029 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085236 | Oldak et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts, Amherst (Amherst, Massachusetts) |
| INVENTOR(S) | Salomon Oldak (Los Angeles, California); Wei-Bo Gong (Amherst, Massachusetts); Christopher V. Hollot (Easthampton, Massachusetts); Don Towsley (Amherst, Massachusetts); Vishal Misra (New York, New York); Yossi Chait (Longmeadow, Massachusetts) |
| ABSTRACT | A method of regulating queuing delay in a network routing device independent of TCP loading is provided including receiving data packets, monitoring the data packets using token buckets and a Proportional and Integral (P+I) Active Queue Management (AQM) scheme, marking selected data packets falling within a profile, and adjusting flow preference of the monitored packets. |
| FILED | Monday, May 20, 2002 |
| APPL NO | 10/151638 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Multiplex communications 370/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085301 | Choquette et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The Furukawa Electric Co., Ltd. (Chiyoda-ku, Japan) |
| INVENTOR(S) | Kent D. Choquette (Urbana, Illinois); Noriyuki Yokouchi (Yokohama, Japan) |
| ABSTRACT | The invention is directed to a photonic crystal defect structure for a vertical cavity surface emitting laser (VCSEL). In accordance with the invention, a set of holes is formed in a pattern with one or more missing holes forming a defect in the pattern of the photonic crystal, according to a proscribed depth, hole diameter, and pattern pitch which will insure operation in a single transverse mode. |
| FILED | Friday, July 11, 2003 |
| APPL NO | 10/618034 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/50.124 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07085451 | Gaylord et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Thomas K. Gaylord (Atlanta, Georgia); Gregory D. Van Wiggeren (Los Gatos, California); Donald D. Davis (Duluth, Georgia); Elias N. Glytsis (Dunwoody, Georgia); Emmanuel Anemogiannis (Atlanta, Georgia) |
| ABSTRACT | The present invention relates to a type of optical fiber grating having an azimuthal refractive-index perturbation. The optical fiber includes a fiber grating that has a plurality of grating elements formed therein. At least one of the grating elements has a spatially varying index of refraction that varies azimuthally about the centerline of the optical fiber. The fiber grating acts as a band-stop optical spectral filter. In addition, since fiber-cladding modes are weakly-guided modes, their power can be easily dissipated by scattering, bending, stretching, and/or rotating the optical fiber. Multiple configurations of these gratings within an optical fiber are given. Methodologies are given for the fabrication of these gratings. Devices are presented which can dynamically attenuate, tune, switch, or modulate the wavelength spectral characteristics of an optical signal. |
| FILED | Tuesday, September 06, 2005 |
| APPL NO | 11/220337 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/37 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07083909 | Rutledge et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jackie J. Rutledge (Madison, Wisconsin); Mark E. Cook (Madison, Wisconsin); Ricky L. Monson (Madison, Wisconsin); Crague E. Cook (Madison, Wisconsin); Niels Jorgensen (Madison, Wisconsin) |
| ABSTRACT | A composition that contains a gamete or an embryo and animal white yolk is disclosed. Also disclosed are applications of the composition. |
| FILED | Thursday, March 13, 2003 |
| APPL NO | 10/388150 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07083980 | Reznikoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William S. Reznikoff (Madison, Wisconsin); Mindy M. Steiniger-White (Madison, Wisconsin); Jeremy D. Metzler (New Franken, Wisconsin) |
| ABSTRACT | Tn5 transposase (Tnp) mutants that have higher transposase activities than the wild-type Tnp are disclosed. The Tn5 Tnp mutants differ from the wild-type Tnp at amino acid positions 54, 242, and 372 and have greater avidity than the wild-type Tnp for at least one of a wild-type Tn5 outside end sequence as defined by SEQ ID NO:3 and a modified Tn5 outside end sequence as defined by SEQ ID NO:5. Also disclosed are various systems and methods of using the Tnp mutants for in vitro or in vivo transposition. |
| FILED | Friday, April 16, 2004 |
| APPL NO | 10/826573 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084083 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); The Governors of the University of Alberta (Edmonton, Canada) |
| INVENTOR(S) | Leslie Leah Anderson (Missoula, Montana); Mary Ann Davies (Missoula, Montana); Anthony Clement Petrilli (Florence, Montana); Mark Y. Ackerman (Sherwood Park, Canada) |
| ABSTRACT | The invention is a new heat and fire resistant material. The material is made of a woven silica-based cloth layered in several possible combinations with foil and fiberglass cloth layers. The layers can be arranged in a variety of sequences to minimize the thermal radiation to the inside of the material, but a foil layer must always be the outermost layer to provide protection from radiant heat. |
| FILED | Friday, December 19, 2003 |
| APPL NO | 10/742462 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fabric 442/233 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07084199 | Chou et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Dow Chemical Company (Midland, Michigan) |
| INVENTOR(S) | Chai-Jing Chou (Missouri City, Texas); Eddy I. Garcia-Meitin (Angleton, Texas); Lonnie Schilhab (Lake Jackson, Texas); Richard F. Fibiger (Midland, Michigan) |
| ABSTRACT | A polypropylene nanocomposite composition having at least the following two elements. The first element is a maleated polypropylene polymer having a weight average molecular weight greater than 100,000. The second element is a cation exchanging layered silicate material dispersed in the maleated polypropylene so that more than one half of the layers of the cation exchanging layered silicate material are present as one, two, three, four or five layer units upon examination by electron microscopy. A thermoplastic olefin nanocomposite composition can be obtained by interdispersing a thermoplastic elastomer phase with the above-described polypropylene nanocomposite composition. |
| FILED | Wednesday, December 29, 1999 |
| APPL NO | 10/169483 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 524/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07084436 | DenBaars et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cree, Inc. (Goleta, California) |
| INVENTOR(S) | Steven P. DenBaars (Goleta, California); Eric J. Tarsa (Goleta, California); Michael Mack (Santa Barbara, California); Bernd Keller (Goleta, California); Brian Thibeault (Santa Barbara, California) |
| ABSTRACT | A light emitting diode (LED) grown on a substrate doped with one or more rare earth or transition element. The dopant ions absorb some or all of the light from the LED's active layer, pumping the electrons on the dopant ion to a higher energy state. The electrons are naturally drawn to their equilibrium state and they emit light at a wavelength that depends on the type of dopant ion. The invention is particularly applicable to nitride based LEDs emitting UV light and grown on a sapphire substrate doped with chromium. The chromium ions absorb the UV light, exciting the electrons on ions to a higher energy state. When they return to their equilibrium state they emit red light and some of the red light will emit from the LED's surface. The LED can also have active layers that emit green and blue and UV light, such that the LED emits green, blue, red light and UV light which combines to create white light. Alternatively, it can have one active layer and grown on a sapphire substrate doped with Cr, Ti, and Co such that the substrate absorbs the UV light and emits blue, green, and red light. The invention is also capable of providing a tunable LED over a variety of color shades. The invention is also applicable to solid state laser having one or more active layers emitting UV light with the laser grown on a sapphire substrate doped with one or more rare earth or transition elements. |
| FILED | Wednesday, March 31, 2004 |
| APPL NO | 10/815426 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07084409 | Danielson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | PhotoSense, LLC (Boulder, Colorado) |
| INVENTOR(S) | J. D. Sheldon Danielson (Boulder, Colorado) |
| ABSTRACT | An apparatus for measuring emission time delay during irradiation of targeted samples by utilizing digital signal processing to determine the emission phase shift caused by the sample is disclosed. The apparatus includes a source of electromagnetic radiation adapted to irradiate a target sample. A mechanism generates first and second digital input signals of known frequencies with a known phase relationship, and a device then converts the first and second digital input signals to analog sinusoidal signals. An element is provided to direct the first input signal to the electromagnetic radiation source to modulate the source by the frequency thereof to irradiate the target sample and generate a target sample emission. A device detects the target sample emission and produces a corresponding first output signal having a phase shift relative to the phase of the first input signal, the phase shift being caused by the irradiation time delay in the sample. A member produces a known phase shift in the second input signal to create a second output signal. A mechanism is then provided for converting each of the first and second analog output signals to digital signals. A mixer receives the first and second digital output signals and compares the signal phase relationship therebetween to produce a signal indicative of the change in phase relationship between the first and second output signals caused by the target sample emission. Finally, a feedback arrangement alters the phase of the second input signal based on the mixer signal to ultimately place the first and second output signals in quadrature. Mechanisms for enhancing this phase comparison and adjustment technique are also disclosed. |
| FILED | Tuesday, August 22, 2000 |
| APPL NO | 09/642596 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Radiant energy 250/458.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 01, 2006.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060801.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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