FedInvent™ Patents

Patent Details for Tuesday, September 05, 2006 

This page was updated on Sunday, March 26, 2023 at 08:04 PM GMT

Department of Health and Human Services (HHS) 

US 07100628 Izenson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Creare Inc. (Hanover, New Hampshire)
INVENTOR(S) Michael G. Izenson (Hanover, New Hampshire);  Patrick J. Magari (Plainfield, New Hampshire)
ABSTRACT An electromechanically-assisted control system for use in a second-stage regulator. Regulator control assembly (20), also referred to as EMA assembly (20), includes a mechanical actuator sub-assembly (21) and an electromechanical actuator (EMA) sub-assembly (22) for controlling airflow through single air supply line (23). EMA sub-assembly (22) includes electronically controllable actuator (ECA) (34), which removably seals EMA orifice (36) in wall (30) of pilot chamber (32). ECA (34) is electrically connected with and controlled by control electronics (38). The control electronics include programmable microprocessor (40), which is electrically connected with charge and discharge electronics (42), both of which are electrically connected with power supply (44). Alternatively, regulator control assembly (20′), also referred to as all-electronic (AE) assembly (20′), has only an EMA sub-assembly and no mechanical actuator sub-assembly. AE assembly (20′) does not include a low-pressure diaphragm, a lever arm, a first valve, or a pilot jet orifice.
FILED Tuesday, November 18, 2003
APPL NO 10/718273
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101540 Kaspar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Salk Institute For Biological Studies (La Jolla, California)
INVENTOR(S) Brian K. Kaspar (San Diego, California);  Fred H. Gage (La Jolla, California)
ABSTRACT Methods are disclosed for delivering a heterologous gene to a cell body of a neuron by contacting a muscle tissue innervated by the neuron with a viral vector comprising a heterologous gene, wherein the viral vector enters said neuron and is retrogradely moved to the cell body. Additionally, methods for expressing secreted proteins from a nerve cell body as well as methods for treating neurodegenerative disorders such as amyotrophic lateral sclerosis are described.
FILED Thursday, September 05, 2002
APPL NO 10/237567
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
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US 07101541 Hu et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Wei-Shau Hu (Frederick, Maryland);  Vinay K. Pathak (Frederick, Maryland)
ABSTRACT A retroviral vector for gene reconstitution is provided that includes a 3′ portion of a heterologous nucleic acid sequence 5′ of a first att site and a 5′ portion of the heterologous nucleic acid sequence 3′ of a second att site. A sub-portion of the 3′ portion of the heterologous nucleic acid sequence and a sub-portion the 5′ portion of the heterologous nucleic acid sequence are direct repeats. A retroviral vector for gene reconstitution is also provided that includes a 3′ portion of a heterologous nucleic acid sequence inserted into or adjacent to a 5′ retroviral terminal repeat of the retroviral vector, and a 5′ portion of the heterologous nucleic acid sequence inserted into or adjacent to a 3′ retroviral terminal repeat of the retroviral vector, wherein the 3′ and the 5′ retroviral terminal repeats each comprise an att site. Methods and kits are also provided.
FILED Tuesday, May 15, 2001
APPL NO 10/276602
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101547 Tripp et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ralph A. Tripp (Decatur, Georgia);  Larry J. Anderson (Atlanta, Georgia);  Deborah D. Moore (Marietta, Georgia)
ABSTRACT The present invention provides methods for preventing or treating a disease in a subject which is caused by an inflammatory response to a disease or syndrome which is mediated by endogenous substance P. These methods comprise the administration to the subject of a pharmaceutically-effective amount of anti-substance P antibodies, or anti-substance P antibody fragments, such as F(ab)2 fragments, thereby inhibiting the activity of endogenous substance P in the subject. By inhibiting the activity of endogenous substance P in the subject, the levels of cytokines produced by T lymphocytes present in the subject are reduced, the signals which direct the inflammatory response to the infection become altered, and the amount of cytokine-induced inflammation becomes reduced. Respiratory syncytial virus is one example of an agent which causes an infection which often results in a disease caused by an inflammatory response to the infection mediated by endogenous substance P. Generally, from about 0.001 mg to about 10 g of anti-substance P antibodies, or anti-substance P antibody fragments, per kilogram of body weight per day are administered to a mammalian subject, with from about 1 mg to about 1000 mg of anti-substance P antibodies, or anti-substance P antibody fragments, per kilogram of body weight per day being preferred.
FILED Friday, January 14, 2000
APPL NO 09/889317
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
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US 07101548 Cuttitta et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Frank Cuttitta (Adamstown, Maryland);  Alfredo Martinez (McLean, Virginia);  Mae Jean Miller (Monrovia, Maryland);  Edward J. Unsworth (Kensington, Maryland);  William Hook (Wheaton, Maryland);  Thomas Walsh (Bethesda, Maryland);  Karen Gray (Gaithersburg, Maryland);  Charles Macri (Kensington, Maryland)
ABSTRACT The methods of the present invention demonstrate that adrenomedullin (AM) is expressed in human cancer cell lines of diverse origin and functions as a universal autocrine growth factor driving neoplastic proliferation. The present invention provides for AM peptides and AM antibodies useful in therapeutic, pharmacologic and physiologic compositions. The present invention additionally provides for methods of diagnosis, treatment and prevention of disease utilizing compositions comprising the AM peptides and antibodies of the present invention. The methods of the present invention also provide for experimental models for use in identifying the role of AM in pancreatic physiology. The methods pertaining to rat isolated islets have shown that AM inhibits insulin secretion in a dose-dependent manner. The monoclonal antibody MoAb-G6, which neutralizes AM bioactivity, was shown by the methods of the present invention to increase insulin release fivefold, an effect that was reversed by the addition of synthetic AM.
FILED Thursday, August 16, 2001
APPL NO 09/931700
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101550 Wood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  Genetics Institute, LLC (Cambridge, Massachusetts)
INVENTOR(S) Clive Wood (Boston, Massachusetts);  Gordon J. Freeman (Brookline, Massachusetts)
ABSTRACT The invention identifies PD-1 as a receptor for B7-4. B7-4 can inhibit immune cell activation upon binding to an inhibitory receptor on an immune cell. Accordingly, the invention provides agents for modulating PD-1, B7-4, and the interaction between B7-4 and PD-1 in order to modulate a costimulatory or an inhibitory signal in a immune cell resulting in modulation of the immune response.
FILED Wednesday, February 06, 2002
APPL NO 10/068215
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/144.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101552 Haynes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Barton F. Haynes (Durham, North Carolina);  Dhavalkumar D. Patel (Durham, North Carolina);  Munir Alam (Chapel Hill, North Carolina);  Hua-Xin Liao (Chapel Hill, North Carolina)
ABSTRACT The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates. The invention also relates to a method of inducing anti-HIV antibodies using same.
FILED Monday, September 24, 2001
APPL NO 09/960717
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/178.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101557 Thorpe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents The University of Texas System (Austin, Texas)
INVENTOR(S) Philip E. Thorpe (Dallas, Texas);  Steven W. King (Foothill Ranch, California);  Boning Gao (Dallas, Texas)
ABSTRACT The invention embodies the surprising discovery that Tissue Factor (TF) compositions and variants thereof specifically localize to the blood vessels within a vascularized tumor following systemic administration. The invention therefore provides methods and compositions comprising coagulant-deficient Tissue Factor for use in effecting specific coagulation and for use in tumor treatment. The TF compositions and methods of present invention may be used alone, as TF conjugates with improved half-life, or in combination with other agents, such as conventional chemotherapeutic drugs, targeted immunotoxins, targeted coaguligands, and/or in combination with Factor VIIa (FVIIa) or FVIIa activators.
FILED Thursday, February 27, 2003
APPL NO 10/375741
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/198.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101558 Merkel et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Tod J. Merkel (Bethesda, Maryland);  Jerry M. Keith (Olney, Maryland);  Xiaoming Yang (Rockville, Maryland)
ABSTRACT The present invention provides a vaccine production strain of Bordetella bronchiseptica that produces a pertussis toxin in high yield. The present invention provides a method for creating a Bordetella bronchiseptica cell line which produces a Bordetella pertussis toxin comprising the steps of introducing a plasmid containing a DNA encoding antibiotic resistance into a Bordetella bronchiseptica strain, selecting for isolates in which the DNA encoding antibiotic resistance is recombinantly incorporated into the chromosome in place of the Bordetella bronchiseptica toxin gene, introducing a plasmid containing DNA encoding subunits of the Bordetella pertussis toxins into the Bordetella bronchiseptica isolates; and, selecting for isolates in which DNA encoding Bordetella pertussis toxin subunit is recombinantly incorporated into the chromosome, the resulting cells producing the Bordetella pertussis toxin. The present invention further provides a method for creating a Bordetella bronchiseptica cell line which produces a Bordetella pertussis toxin and does not express filamentous hemagglutinin.
FILED Tuesday, June 26, 2001
APPL NO 10/312272
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/200.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101562 Lees et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Forsyth Institute (Boston, Massachusetts);  Henry M. Jackson Foundation for the Advancement of Military Medicine (Rockville, Maryland)
INVENTOR(S) Andrew Lees (Silver Spring, Maryland);  Martin A. Taubman (Newton, Massachusetts);  Daniel J. Smith (Natick, Massachusetts)
ABSTRACT The present invention provides glucan-based compositions and methods for stimulating an immune response against mutans streptococci components and vaccines and methods for the treatment and prevention of dental caries. In a preferred embodiment, a glucan polymer, preferably WSG, is covalently bound to one or more T cell-dependent antigens to form a conjugate vaccine. The T cell-dependent antigen preferably contains epitopes of one or more mutans streptococcal proteins, such as a glucosyltransferase. Moreover, one or more moieties, including haptens, may be conjugated to the glucan-T cell-dependent composition. In a preferred embodiment, these moieties are peptides which contain immunogenic epitopes corresponding to components of a mutans streptococcus.
FILED Monday, May 01, 2000
APPL NO 09/562328
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/244.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101663 Godfrey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Tony E. Godfrey (Pittsburgh, Pennsylvania);  James D. Luketich (Pittsburgh, Pennsylvania);  Siva Raja (Pittsburgh, Pennsylvania);  Lori A. Kelly (Jeanette, Pennsylvania);  Sydney D. Finkelstein (Pittsburgh, Pennsylvania)
ABSTRACT A method for balancing multiplexed PCR methods is provided. In the method, two or more sequential temporal PCR stages are used to effectively separate two or more PCR reactions in a single tube as an alternative to primer limiting to modulate the relative rate of production of a first amplicon by a first primer set and a second amplicon by a second primer set during the first and second amplification stages. Also provided are rapid RT-PCR methods that find particular use in intraoperative diagnoses and prognoses, for instance in diagnosing malignant esophageal adenocarcenoma by determining expression levels of carcinoembryonic antigen (CEA) in sentinel lymph nodes.
FILED Monday, March 04, 2002
APPL NO 10/090326
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101684 Khosla et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Stanford University (Stanford, California);  Brown University Research Foundation (Providence, Rhode Island)
INVENTOR(S) Chaitan Khosla (Palo Alto, California);  Rembert Pieper (Washington, District of Columbia);  Guanglin Luo (Madison, Connecticut);  David Cane (Providence, Rhode Island)
ABSTRACT Modular polyketide synthases modified so as not to incorporate natural starter units can be used for clean synthesis of novel polyketides.
FILED Friday, February 27, 2004
APPL NO 10/788650
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101692 Schneewind et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Olaf Schneewind (Chicago, Illinois);  Sarkis K. Mazmanian (Brookline, Massachusetts);  Gwen Liu (Los Angeles, California);  Hong Ton-That (Chicago, Illinois)
ABSTRACT The present invention is a substantially purified sortase-transamidase enzyme from Gram-positive bacteria, such as Staphylococcus aureus. A specific sortase-transamidase enzyme disclosed has a molecular weight of about 29,076 daltons and catalyzes a reaction that covalently cross-links the carboxyl terminus of a protein having a sorting signal to the peptidoglycan of a Gram-positive bacterium, where the sorting signal has a a motif of NPQ/KTN/G therein. Variants of the enzyme, methods for cloning the gene encoding the enzyme and expressing the cloned gene, and methods of use of the enzyme, including for screening for antibiotics and for display of proteins or peptides on the surfaces of Gram-positive bacteria, are also disclosed.
FILED Wednesday, August 14, 2002
APPL NO 10/219700
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/183
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101707 Castellon
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Raquel Castellon (Norwalk, California)
ABSTRACT In vitro methods are disclosed that rely on a novel phenomenon of secondary sprouting by cultured endothelial precursor cells, after angiogenic-like tube formation and collapse have occurred on a basement membrane matrix. Particularly disclosed is an in vitro method of isolating and expanding, from a mixed population of mammalian cells originating from a tissue sample, a cellular population enriched for endothelial sprout cells, including cells having one or more physiological and/or immunological features of endothelial precursor cells. Also disclosed is an in vitro method for a screening a substance for potential proangiogenic or antiangiogenic activity.
FILED Monday, December 23, 2002
APPL NO 10/328812
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101838 Stern et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) David Stern (Great Neck, New York);  Ann Marie Schmidt (Franklin Lakes, New Jersey)
ABSTRACT The present invention provides for a method to prevent accelerated atherosclerosis in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproduct in an amount effective to prevent accelerated atherosclerosis in the subject. The present invention also provides for a method to prevent a macrovessel disease in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproduct in an amount effective to prevent macrovessel disease in the subject.
FILED Tuesday, August 05, 1997
APPL NO 08/905709
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101845 Maratos-Flier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Joslin Diabetes Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Eleftheria Maratos-Flier (Newton, Massachusetts);  Rohit N. Kulkarni (Brookline, Massachusetts);  Pavlos Pissios (Boston, Massachusetts)
ABSTRACT Methods of modulating pancreatic function by modulating MCH signaling in a β cell.
FILED Friday, January 31, 2003
APPL NO 10/355645
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101846 Winslow
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert M. Winslow (La Jolla, California)
ABSTRACT Compositions, and methods of use thereof, for use as blood substitute products comprise aqueous mixtures of oxygen-carrying and non-oxygen carrying plasma expanders and methods for the use thereof. The oxygen-carrying component may consist of any hemoglobin-based oxygen carrier, while the non-oxygen carrying plasma expander my consist of any suitable diluent.
FILED Wednesday, August 11, 2004
APPL NO 10/917223
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101850 Levine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Genentech, Inc. (South San Francisco, California)
INVENTOR(S) Arnold J. Levine (New York, New York);  Diane Pennica (Burlingame, California)
ABSTRACT Wnt-1-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
FILED Wednesday, March 27, 2002
APPL NO 10/112267
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101852 Fujise et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Kenichi Fujise (Houston, Texas);  Zakar H. Mnjoyan (Houston, Texas)
ABSTRACT Compositions and methods are disclosed which employ PARIS proteins that are useful for suppressing proliferation of smooth muscle cells. Preferred PARISs are soluble proteins that are secreted by vascular smooth muscle cells, and include PARIS-1 (neuronal pentraxin 1), PARIS-2 (SBP (MIC-1, GDF-15), PARIS-3 (BTG2) and PARIS-4 (soluble fractalkine). Methods of preventing or treating restenosis by administering the new compositions are disclosed. Also disclosed are methods for treating patients undergoing angioplasty procedures, patients with atherosclerosis, and patients with other proliferative disorders, in order to suppress the growth of vascular smooth muscle cells or other cells that play a role in the particular proliferative disorder or condition. A method of screening mRNAs and identifying genes encoding PARISs is also disclosed.
FILED Friday, May 30, 2003
APPL NO 10/448664
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101865 Posner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cytochroma Inc. (Markham, Canada);  Johns Hopkins Univ. (Baltimore, Maryland)
INVENTOR(S) Gary H. Posner (Baltimore, Maryland);  Mehmet Kahraman (Baltimore, Maryland);  Uttam Saha (Toronto, Canada)
ABSTRACT The present invention provides novel sulfoximine compounds, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modulation of the levels of 1α,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.
FILED Friday, June 13, 2003
APPL NO 10/460656
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/167
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US 07101975 Brooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Peter C. Brooks (West Harrison, New York);  Dorothy Rodriguez (West Harrison, New York)
ABSTRACT Antagonists for modifying protein-protein interactions involving certain amino acid sequences within MMP-9 and/or β1 integrins are described. Such antagonists inhibit angiogenesis, tumor growth and disease states. Example antagonists are polypeptide and non-polypeptide molecules, including the novel antibody Mab FM155 and the novel synthetic peptide FRIP-1. Methods for inhibiting angiogenesis and disease states by administering such antagonists are disclosed. Methods for identifying antagonists that modify protein-protein interactions involving certain amino acid sequences within MMP-9 and/or β1 integrins are also described.
FILED Thursday, July 13, 2000
APPL NO 09/615624
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101979 Boehm et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Thomas Boehm (Brookline, Massachusetts);  Michael S. O'Reilly (Winchester, Massachusetts);  M. Judah Folkman (Brookline, Massachusetts)
ABSTRACT Antibody to endostatin protein that is an inhibitor of endothelial cell proliferation, capable of inhibiting angiogenesis and causing tumor regression, that is approximately 18 kDa as determined by non-reduced gel electrophoresis, and approximately 20 kDa as determined by reduced gel electrophoresis and corresponds to a C-terminal fragment of collagen type XVIII, and methods of detecting and treating angiogenesis-related disease therewith.
FILED Thursday, May 09, 2002
APPL NO 10/142707
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101989 Elkins
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Christopher Elkins (Chapel Hill, North Carolina)
ABSTRACT DsrA is an outer membrane protein of H. ducreyi that confers serum resistance to the bacteria. Isolated polynucleotides encoding the protein, end expression vectors and host cells encoding the same, are described. Also described is a mutant H. ducreyi strain that does not express DsrA. Vaccines against H. ducreyi and methods of using the same are also described.
FILED Friday, July 07, 2000
APPL NO 10/030529
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102005 Agnew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Molecular Probes, Inc. (Eugene, Oregon)
INVENTOR(S) Brian Agnew (Eugene, Oregon);  Joseph Beechem (Eugene, Oregon);  Kyle Gee (Springfield, Oregon);  Richard Haugland (Eugene, Oregon);  Jixiang Liu (Eugene, Oregon);  Vladimir Martin (Eugene, Oregon);  Wayne Patton (Eugene, Oregon);  Thomas Steinberg (Eugene, Oregon)
ABSTRACT The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target molecules that interact with phosphorylated target molecules or molecules capable of being phosphorylated. A binding solution is provide that comprises a phosphate-binding compound, an acid and a metal ion wherein the metal ion simultaneously interacts with an exposed phosphate group on a target molecule and the metal chelating moiety of the phosphate-binding compound forming a bridge between the phosphate-binding compound and a phosphorylated target molecule resulting in a ternary complex. The binding solution of the present invention finds use in binding and detecting immobilized and solubilized phosphorylated target molecules, isolation of phosphorylated target molecules from a complex mixture and aiding in proteomic analysis wherein kinase and phosphatase substrates and enzymes can be identified.
FILED Friday, May 02, 2003
APPL NO 10/428192
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
544/287
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102023 Buchwald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Stephen L. Buchwald (Newton, Massachusetts);  Obadiah J. Plante (Beverly, Massachusetts);  Peter H. Seeberger (Cambridge, Massachusetts)
ABSTRACT One aspect of the present invention relates to optionally substituted halogenated benzyl halides and the like. These compounds are useful as halogenated benzyl ether-based protecting groups for a variety of functional groups. Another aspect of the present invention relates to use of said protecting groups in an orthogonal protecting group strategy for the synthesis of complex molecules that comprise a number of suitable functional groups. Another aspect of the present invention relates to saccharides bearing various arrays of protecting groups of the present invention. Another aspect of the present invention relates to a method of synthesizing an oligosaccharide or glycoconjugate, comprising the steps of: using a saccharide bearing at least one protecting group of the present invention to glycosylate a second molecule to give a product comprising said saccharide; and removing a protecting group of the present invention from said product.
FILED Friday, February 06, 2004
APPL NO 10/774070
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
558/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07103399 Miga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Michael I. Miga (Franklin, Tennessee);  Benoit M. Dawant (Nashville, Tennessee);  Tuhin K. Sinha (Nashville, Tennessee)
ABSTRACT A cortical surface registration procedure related to a diagnostic or surgical procedure. In one embodiment, the procedure includes the steps of pre-operatively obtaining a first textured point cloud of the cortical surface of a targeted region of a brain of a living subject, intra-operatively obtaining optically a second textured point cloud of the cortical surface of the brain of the living subject, and aligning the first textured point cloud of the cortical surface to the second textured point cloud of the cortical surface so as to register images of the brain of the living subject to the cortical surface of the living subject.
FILED Wednesday, September 08, 2004
APPL NO 10/936339
ART UNIT 3737 — Optics
CURRENT CPC
Surgery
6/425
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07103401 Schomacker et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) MediSpectra, Inc. (Lexington, Massachusetts)
INVENTOR(S) Kevin T. Schomacker (Maynard, Massachusetts);  Norman S. Nishioka (Wayland, Massachusetts);  Alex R. Zelenchuk (Stoughton, Massachusetts)
ABSTRACT A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, about 403 nm, about 414 nm, and about 431 nm. The intensities of the 403 nm and 414 mn radiation are normalized using the 431 nm intensity. A score is determined using the ratios in a linear discriminant analysis (LDA). The tissue under examination is resected or not, based on the outcome of the LDA.
FILED Wednesday, July 10, 2002
APPL NO 10/192820
ART UNIT 2877 — Optics
CURRENT CPC
Surgery
6/476
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 07100299 Jensen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) David G. Jensen (Auburn, Washington);  David M. Pett (Seattle, Washington);  Paul Buehler (Mill Creek, Washington)
ABSTRACT A system, for installation of fastening systems to a structure, includes a fastening system installation specification, which includes dimensional and qualitative requirements for components of the fastening systems; and a tool. The tool includes an outer housing having an interior hollow, a gage surface, and a base surface, the base surface having a contact area that contacts the surface of the structure. An inner plug disposed within the interior hollow translates axially within the interior hollow. The inner plug has a sensing end that contacts a bolt of the fastening system and references the shank section of the bolt. The inner plug has an indicator end dimensioned to accept washers and nuts of the fastening system stacked on the gage surface. The inner plug has an indicator that provides installation information, according to either qualitative or dimensional requirements, about the components of the fastening system being installed using the tool.
FILED Monday, January 30, 2006
APPL NO 11/344324
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Geometrical instruments
033/645
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07100355 Wieger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) George S. Wieger (Niles, Michigan);  David W. Rice (Niles, Michigan)
ABSTRACT A fuel control system, battle override valve and a method of controlling bypass fuel in a fuel system are disclosed. A battle override valve 30 for an engine fuel system 10 includes a metering valve 50 having a rate limiting function providing for control of a slew rate during an operation of the battle override valve 30. A transfer valve 70 having a manual fuel control operating position and a normal fuel control operating position permits a flow of fuel between the metering valve 50 and the transfer valve 70. The transfer valve 70 is controlled between the normal fuel control operating position and the manual fuel control operating position in order to regulate a flow of fuel during a manual or bypass fuel system 10 operation.
FILED Friday, March 05, 2004
APPL NO 10/794731
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/39.91
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07100468 Gmirya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
INVENTOR(S) Yuriy Gmirya (Woodbridge, Connecticut);  Harsh Vinayak (Meriden, Connecticut);  David Andrew Binney (Beacon Falls, Connecticut);  Lawrence Mark Zunski (Seymour, Connecticut);  Vincent F. Millea (Stratford, Connecticut)
ABSTRACT A split torque gearbox having multiple input shafts. Each input shaft is connected to two face gears. Each face gear is connected to two quill shafts, one is coaxially mounted and the second is not coaxially mounted. Of the two quill shafts, one is positioned on a first side of an output stage and a second quill shaft is located on a second side of the output stage and the quill shafts are connected thereto. The output stage is connected to a main shaft.
FILED Thursday, December 18, 2003
APPL NO 10/740375
ART UNIT 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Machine element or mechanism
074/410
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07100489 Kendall
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Donald H. Kendall (Chassell, Michigan)
ABSTRACT For use in landmine clearing, a hitch system providing backup with anti-jack knife and anti-dive, the system includes a hitch assembly and a roller assembly. The hitch assembly has a hinge axis housing containing a hinge shaft and a connector shaft housing containing a stop block having a first side that engages a flat region on the hinge shaft and a second side that engages a biasing spring that is held in the connector shaft housing using an end cap. The roller assembly includes a roller frame that is rigidly mechanically coupled to the hinge shaft. The biasing spring is selected to provide a compressive bias to the stop block such that the roller assembly selective rotates about the hinge axis housing when the roller assembly is subjected to a landmine detonation, and such that rotation of the hinge shaft is prevented during normal forward, reverse, and turning maneuvers.
FILED Monday, July 11, 2005
APPL NO 11/178065
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/1.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07100635 Wagner
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) George W. Wagner (Elkton, Maryland)
ABSTRACT A large-scale system for storage and mixing of a solution comprising a plurality of ingredients not compatible for long-term storage in a pre-mixed formulation includes a storage tank that is divided into a plurality of compartments each of which is adapted to isolate and store a proportionate amount of ingredient, fluid conduits for withdrawing and conveying the ingredients from the compartments, valves for controlling the flow of ingredients and for preventing backflow, a manifold for continuous mixing and blending of the ingredients as they are withdrawn, a sump for holding a quantity of the mixed solution, a display to enable monitoring of system parameters and a discharge port to which conduits may be coupled for withdrawing the mixed solution from the system.
FILED Thursday, October 16, 2003
APPL NO 10/687287
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/590
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101115 Luthy et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Richard G. Luthy (Stanford, California);  Upal Ghosh (Ellicott City, Maryland)
ABSTRACT To overcome obstacles faced by current remediation technologies for contaminated sediments, the present invention provides a new strategy based on in situ control of hydrophobic organic contaminants (HOC) bioavailability. The strategy employs the addition of activated carbon sorbents to sediments. These activated carbon materials sorb HOC contaminants strongly, reduce release of HOCs into water, and reduce HOC uptake by benthic biota, thereby reducing environmental exposure and human health risk to such contaminants. By in situ sorbing the contaminants, the inventive approach reduces environmental exposure and avoids massive material removal while controlling food web transfer of HOCs including polychlorinated biphenyls (PCBs).
FILED Wednesday, October 16, 2002
APPL NO 10/272681
ART UNIT 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Hydraulic and earth engineering
45/128.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101146 Coull et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Jennifer A. Coull (Lake Worth, Florida);  John P. Nikkanen (West Hartford, Connecticut)
ABSTRACT A gas path flow blocker comprising a plurality of vanes each comprising a forward portion and an aft portion defining a plurality of gas paths, a forward ring comprising a central axis about which is circumferentially disposed the plurality of forward portions, and an aft ring disposed about the central axis about which is circumferentially disposed the plurality of aft portions wherein the forward ring and the aft ring are moveable with respect to each other to at least partially block the flow of a gas through the gas paths.
FILED Tuesday, December 16, 2003
APPL NO 10/737599
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/127
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101237 Dai
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Charles M. Dai (Potomac, Maryland)
ABSTRACT The stern end of a seawater hull has a rotor hub with propeller blades thereon. The rotor hub is rotated for propulsion of the hull by means of a propeller shaft extending through a sealed compartment within the hull. Such sealed compartment and an electrically powered control system is disposed within the hull to automatically adjust angular deflection of deformable tip portions of the propeller blades by means of blade embedded actuators, in response to varying input signals which respectively reflect changes in seawater conditions such as temperature and strain imposed on the propeller blades during propelling rotation of the rotor hub.
FILED Thursday, June 03, 2004
APPL NO 10/863843
ART UNIT 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Marine propulsion
440/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101562 Lees et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Forsyth Institute (Boston, Massachusetts);  Henry M. Jackson Foundation for the Advancement of Military Medicine (Rockville, Maryland)
INVENTOR(S) Andrew Lees (Silver Spring, Maryland);  Martin A. Taubman (Newton, Massachusetts);  Daniel J. Smith (Natick, Massachusetts)
ABSTRACT The present invention provides glucan-based compositions and methods for stimulating an immune response against mutans streptococci components and vaccines and methods for the treatment and prevention of dental caries. In a preferred embodiment, a glucan polymer, preferably WSG, is covalently bound to one or more T cell-dependent antigens to form a conjugate vaccine. The T cell-dependent antigen preferably contains epitopes of one or more mutans streptococcal proteins, such as a glucosyltransferase. Moreover, one or more moieties, including haptens, may be conjugated to the glucan-T cell-dependent composition. In a preferred embodiment, these moieties are peptides which contain immunogenic epitopes corresponding to components of a mutans streptococcus.
FILED Monday, May 01, 2000
APPL NO 09/562328
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/244.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101589 Hawkins
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) James H. Hawkins (Phoenix, Arizona)
ABSTRACT A method for protecting from corrosion an element comprised of magnesium or a magnesium alloy comprises applying an adhesion promoter after applying a chromate solution to a surface of the element, whereby the chromate solution creates a corrosion-resistant chromate layer on the surface. The method further includes applying an organic coating, such as a resin seal, over the adhesion promoter so as to provide a seal from water and corrosive elements. The adhesion promoter provides improved adhesion between the chromate layer and the organic coating. Corrosion may be removed from the magnesium element before the application of the chromate solution.
FILED Tuesday, June 28, 2005
APPL NO 11/168065
ART UNIT 1775 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Coating processes
427/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101607 Mollendorf et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Joseph C. Mollendorf (Amherst, New York);  David Pendergast (Hamburg, New York);  Erik R. Bardy (Buffalo, New York);  Sawson Samimy (Geneva, New York);  Eric M. Stimson (North Tonawanda, New York);  Colin K. Dauria (Syracuse, New York);  Raymond D. Buchner (Clarence, New York)
ABSTRACT The present invention relates to a composite insulation material. The composite insulation material includes a syntactic foam component and a plurality of aerogel inserts. The present invention also relates to a method of making a composite insulation material. The present invention further relates to a method for enhancing the flexibility of a solid material.
FILED Thursday, August 21, 2003
APPL NO 10/645726
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Stock material or miscellaneous articles
428/158
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101808 Tucker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Wayne C. Tucker (Exeter, Rhode Island);  Maria G. Medeiros (Bristol, Rhode Island);  Richard Brown (Wakefield, Rhode Island)
ABSTRACT Non-chromate solutions for treating and/or etching metals, particularly, aluminum, aluminum alloys, steel and titanium, and method of applying same wherein the solutions include either a titanate or titanium dioxide as a “drop-in replacement” for a chromium-containing compound in a metal surface etching solution that otherwise would contain chromium.
FILED Monday, October 06, 2003
APPL NO 10/679683
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Semiconductor device manufacturing: Process
438/745
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101894 McMaster et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) ChemoCentryx, Inc. (Mountain View, California)
INVENTOR(S) Brian E. McMaster (Mountain View, California);  Thomas J. Schall (Palo Alto, California);  Mark Penfold (Mountain View, California);  J. J. Wright (Redwood City, California);  Daniel J. Dairaghi (Palo Alto, California)
ABSTRACT Methods for treating CMV or a CMV-related disease are provided that use compounds having the formula:
wherein Ar is a substituted or unsubstituted 5–14 membered heteroaryl group having from 1 to 5 heteroatoms as ring members; R1 is selected from the group consisting of substituted or unsubstituted aryl(C1–C4)alkyl, heteroaryl(C1–C4)alkyl, —C(O)R11, and —C(O)NR11R12, wherein each R11 and R12 independently is substituted or unsubstituted aryl, substituted or unsubstituted aryl(C1–C4)alkyl, substituted or unsubstituted (C4–C8)cycloalkyl(C1–C4)alkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroaryl(C1–C4)alkyl and substituted or unsubstituted hetero(C4–C8)cycloalkyl(C1–C4)alkyl; R2 is H or (C1–C8)alkyl; and ZN is a substituted or unsubstituted hetero(C6–C10)bicycloalkyl group.
FILED Thursday, August 29, 2002
APPL NO 10/233326
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/305
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07101902 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ai Jeng Lin (North Potomac, Maryland);  Quan Zhang (Montgomery County, Maryland);  Jian Guan (Montgomery County, Maryland);  Wilbur K. Milhous (Germantown, Maryland)
ABSTRACT Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural formula A or B
wherein R1 and R2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R3 is an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.
FILED Friday, November 19, 2004
APPL NO 10/992363
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/390
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102052 McVey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Steris INC (Temecula, California);  The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Iain F. McVey (Lakewood, Ohio);  Lewis I. Schwartz (Shaker Heights, Ohio);  Michael A. Centanni (Parma, Ohio);  George W. Wagner (Elkton, Maryland)
ABSTRACT Hydrogen peroxide is vaporized (20) and mixed (30) with ammonia gas in a ratio between 1:1 and 1:0.0001. The peroxide and ammonia vapor mixture are conveyed to a treatment area (10) to neutralize V-type, H-type, or G-type chemical agents, pathogens, biotoxins, spores, prions, and the like. The ammonia provides the primary deactivating agent for G-type agents with the peroxide acting as an accelerator. The peroxide acts as the primary agent for deactivating V-type and H-type agents, pathogens, biotoxins, spores, and prions. The ammonia acts as an accelerator in at least some of these peroxide deactivation reactions.
FILED Thursday, April 24, 2003
APPL NO 10/422472
ART UNIT 1754 — Organic Chemistry
CURRENT CPC
Hazardous or toxic waste destruction or containment
588/303
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102387 Lyke
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) James C. Lyke (Albuquerque, New Mexico)
ABSTRACT A simplified implementation of molecular field programmable gate arrays described in U.S. Pat. No. 6,215,327 and U.S. Pat. No. 6,331,788, reducing the complexity in a tiled array template to that of a 1-input lookup table.
FILED Wednesday, December 08, 2004
APPL NO 11/007143
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Electronic digital logic circuitry
326/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102451 Happer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) Princeton University, Office of Technology, Licensing and Intellectual Property (Princeton, New Jersey)
INVENTOR(S) William Happer (Princeton, New Jersey);  Yuan-Yu Jau (Princeton, New Jersey);  Nicholas N. Kuzma (Princeton, New Jersey);  Eli Miron (Omer, Israel);  Amber B. Post (Batesville, Arizona);  Michael V. Romalis (Princeton, New Jersey)
ABSTRACT The present invention provides a method and apparatus for increasing the intensity of coherent population trapping (CPT) resonances, used in atomic clocks and magnetometers, by pumping the atoms with light of alternating polarization. Pumping with such light, characterized by a photon spin vector that alternates in direction at a hyperfine frequency of the atoms at the location of the atoms, is referred to as push-pull pumping. In one embodiment of the system of the present invention, alkali-metal vapor is pumped with alternating circular-polarization D1 laser light that is intensity modulated at appropriate resonance frequencies, thereby exciting CPT resonances, which can be observed as increase in the mean transmittance of the alkali-metal vapor. These resonances are substantially enhanced due to an optically-induced concentration of atoms in the resonant energy sublevels.
FILED Monday, February 07, 2005
APPL NO 11/052261
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/94.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102656 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Jung-Hyurk Lim (Evanston, Illinois)
ABSTRACT A method of nanolithography includes transporting a patterning compound from a nanoscopic tip to a substrate to form a pattern on the substrate. The patterning compound has a first electrostatic charge and the substrate has a second electrostatic charge which is opposite to the first electrostatic charge. The patterning compound can be an electrically conductive polymer having a charged polymer backbone. The patterns can be dots and lines having lateral dimensions of less than one micron. No electrical bias from an external voltage source between the tip and the substrate is needed.
FILED Wednesday, May 21, 2003
APPL NO 10/442188
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Recorders
346/140.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102665 Chandler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Scott Chandler (Panama City Beach, Florida);  Chris Doyle (Panama City Beach, Florida)
ABSTRACT A system and method for imaging underbodies of moving vehicles have a stationary source of radiation to radiate energy upwardly on underbodies of moving vehicles. A stationary video camera adjacent the radiation source on a roadway has an upwardly facing field of view for creating image signals representative of sequential portions of each underbody as each moving vehicle passes overhead. A control station activates the camera and radiation source to create the image signals and creates mosaic signals of all of each underbody from the image signals. A display screen provides a mosaic image of each underbody from its mosaic signals. A virtually real-time inspection or a comparison can be made with previously taken underbody images of the same moving vehicle or with vehicle manufacturers' data for the same vehicular models. Moving cars, trucks, marine vessels, aircraft, can be quickly imaged for inspection and/or comparison by fewer security personnel.
FILED Tuesday, December 10, 2002
APPL NO 10/314563
ART UNIT 2621 — Selective Visual Display Systems
CURRENT CPC
Television
348/148
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07102804 Andersen
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Geoff P. Andersen (Colorado Springs, Colorado)
ABSTRACT The present invention employs a method for transmitting and/or receiving high data bandwidths at reduced cost by employing a holographically corrected telescope for transmitting or receiving data-carrying signals remotely, at IR, optical or UV frequencies for low cost data communication.
FILED Wednesday, January 29, 2003
APPL NO 10/357250
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/16
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US 07102814 Hughes
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Hughes (Lynn Haven, Florida)
ABSTRACT A system shields IR emissions from remote sensors and has a flexible outer metallic layer extending to cover objects emitting IR energy on the covered ground. The outer layer is conductive of heat energy and faces upward. A flexible inner metallic layer coextensively extends adjacent to the outer metallic layer. The inner layer is conductive of heat energy and faces downward. Spaced-apart thermo electric chips are between and in contact with the outer and inner layers. The chips transfer heat energy between the outer and inner layers. A sensor of IR radiation on ambient ground provides signals representative of the thermal signature of the ambient ground. A controller couples signals to the chips in response to the representative ambient ground thermal signals for controlling the heat energy radiated from the outer layer to match the radiated IR signature from the outer layer to the IR signature of the ambient ground.
FILED Monday, August 30, 2004
APPL NO 10/932651
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/350
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US 07103502 O'Brien, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Francis J. O'Brien, Jr. (Newport, Rhode Island)
ABSTRACT A two-step method and apparatus are provided for automatically characterizing the spatial arrangement among the data points of a time series distribution in a data processing system. The method and apparatus utilize a Cartesian grid to determine: the number of cells in the grid containing at least one input data point of the time series distribution; the expected number of cells which would contain at least one data point in a random distribution in said grid; and an upper and lower probability of false alarm bracketing the expected value utilizing a discrete binomial probability relationship in order to analyze the randomness of the input. A statistical test of significance of the sparse data is utilized to determine the existence of noise and signal. The probability of distinguishing noise from signal is increased by comparing the parts of the method.
FILED Wednesday, March 03, 2004
APPL NO 10/794545
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/181
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US 07103614 Kucik
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Daniel P. Kucik (Lynn Haven, Florida)
ABSTRACT A method and system are provided for automatically retrieving information associated with vehicles that must sequentially pass an entrance to a secure site. Prior to the entrance to the secure site, a plurality of vehicles can be aligned in a queue having a front end located at the secure site's entrance. When a vehicle enters the queue, identifying indicia on the vehicle's license tag is automatically transmitted to one or more remotely-located databases in order to retrieve information associated with the license tag. When the vehicle reaches the front of the queue, the information so-retrieved is automatically made available in a human recognizable format to security personnel at the secure site's entrance.
FILED Friday, May 24, 2002
APPL NO 10/154468
ART UNIT 2164 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/104.100
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US H2168 Appleman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) William M. Appleman (Davidsonville, Maryland);  Lawrence P. Murphy (Fairfax, Virginia)
ABSTRACT Elongated processing elements are anchored at opposite ends thereof between holding discs retained within rigid seal rings enclosing a chamber within a cylindrical module housing, through which a flow of contaminate-laden bilgewater is conducted. Such discs are formed within the seal rings with the elongated elements positioned therein by deposit and curing of epoxy resin. Such elements are then assembled within the module housing to seal the chamber thereby established therein. Spacing between the bundled elements is maintained by spacers to accommodate filtration of the bilgewater during flow thereof through the chamber and lateral outflow of a cleansed filtered portion from the elements through a drain outlet.
FILED Wednesday, June 13, 2001
APPL NO 09/879870
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Liquid purification or separation
210/321.720
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US H2171 Adams, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James H. Adams, Jr. (Huntsville, Alabama);  Paul R. Boberg (Valencia, California);  Bruce A. Brownstein (Oxon Hill, Maryland);  William F. Dietrich (Prospect Heights, Illinois);  Erwin O. Flueckiger (Bern, Switzerland);  Edward L. Petersen (Fairfax, Virginia);  Margaret A. Shea (Nashua, New Hampshire);  Don F. Smart (Nashua, New Hampshire);  Edward C. Smith (Oceanside, California);  Allan J. Tylka (Silver Spring, Maryland)
ABSTRACT An aspect of the present invention is a method and apparatus for computing a geomagnetic transmission function. This apparatus includes a programmed digital computer running modeling software for modeling the transmission of cosmic ray particles through the magnetosphere. The software includes a model representing a solution to the Lorentz equation in a magnetic field given by B=BIGRF(r,t′)+BTSYG(Kp,r,t′). Another aspect of the present invention is a method and apparatus for computing a flux of particles at the outer surface of a satellite comprising, inter alia, an improved method and apparatus for computing a flux of solar heavy ions. This apparatus includes a programmed digital computer running modeling software for modeling the flux of cosmic ray particles through the outer surface of a satellite. Another aspect of the invention is a method and apparatus comprising a programmed digital computer running modeling software for modeling the effect of cosmic rays on microelectronics, where this software embodies at least one of the two foregoing aspects of the invention.
FILED Wednesday, December 31, 1997
APPL NO 09/002031
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/2
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US H2172 Staelin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) David H. Staelin (Wellesley, Massachusetts);  Carlos R. Cabrera-Mercader (Somerville, Massachusetts)
ABSTRACT Pitch-synchronous speech processing invention involves two main steps: 1) divide the speech into pitch periods, or into pseudo pitch periods for unvoiced speech, where the breaks occur, for example, at the first zero-crossing preceding each glottal pulse for voiced speech and at any arbitrary point for unvoiced speech, and 2) compute the log-magnitude of the Discrete Fourier Transform (DFT) of each pitch-period waveform, and interpolate each log-magnitude spectrum to a common regular grid which can accommodate the spectrum of a waveform having the longest pitch period anticipated.
FILED Tuesday, July 02, 2002
APPL NO 10/186605
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/207
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Department of Energy (DOE) 

US 07100380 Brasz et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Joost J. Brasz (Fayetteville, New York);  Ulf J. Jonsson (South Windsor, Connecticut)
ABSTRACT A method of operating an organic rankine cycle system wherein a liquid refrigerant is circulated to an evaporator where heat is introduced to the refrigerant to convert it to vapor. The vapor is then passed through a turbine, with the resulting cooled vapor then passing through a condenser for condensing the vapor to a liquid. The refrigerant is one of CF3CF2C(O)CF(CF3)2, (CF3)2 CFC(O)CF(CF3)2, CF3(CF2)2C(O)CF(CF3)2, CF3(CF2)3C(O)CF(CG3)2, CF3(CF2)5C(O)CF3, CF3CF2C(O)CF2CF2CF3, CF3C(O)CF(CF3)2.
FILED Tuesday, February 03, 2004
APPL NO 10/771012
ART UNIT 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Refrigeration
062/114
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US 07100670 Hofman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) Gerard L. Hofman (Downers Grove, Illinois);  Mitchell K. Meyer (Idaho Falls, Idaho);  Gaven C. Knighton (Moore, Idaho);  Curtis R. Clark (Idaho Falls, Idaho)
ABSTRACT A method of producing thin foils of uranium or an alloy. The uranium or alloy is cast as a plate or sheet having a thickness less than about 5 mm and thereafter cold rolled in one or more passes at substantially ambient temperatures until the uranium or alloy thereof is in the shape of a foil having a thickness less than about 1.0 mm. The uranium alloy includes one or more of Zr, Nb, Mo, Cr, Fe, Si, Ni, Cu or Al.
FILED Friday, September 12, 2003
APPL NO 10/660592
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Metal founding
164/76.100
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US 07101527 Poling et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Steven Andrew Poling (Moorefield, West Virginia);  Carly R. Nelson (Ames, Iowa);  Steve W. Martin (Ames, Iowa)
ABSTRACT The present invention provides new amorphous or partially crystalline mixed anion chalcogenide compounds for use in proton exchange membranes which are able to operate over a wide variety of temperature ranges, including in the intermediate temperature range of about 100 ° C. to 300° C., and new uses for crystalline mixed anion chalcogenide compounds in such proton exchange membranes. In one embodiment, the proton conductivity of the compounds is between about 10−8 S/cm and 10−1 S/cm within a temperature range of between about −60 and 300° C. and a relative humidity of less than about 12%.
FILED Wednesday, May 19, 2004
APPL NO 10/848967
ART UNIT 1754 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Chemistry of inorganic compounds
423/592.100
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US 07101635 Zhu et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Los Alamos, New Mexico)
INVENTOR(S) Yimin Zhu (Los Alamos, New Mexico);  Piotr Zelenay (Los Alamos, New Mexico)
ABSTRACT A direct methanol fuel cell (DMFC) having a methanol fuel supply, oxidant supply, and its membrane electrode assembly (MEA) formed of an anode electrode and a cathode electrode with a membrane therebetween, a methanol oxidation catalyst adjacent the anode electrode and the membrane, an oxidant reduction catalyst adjacent the cathode electrode and the membrane, comprises an oxidant reduction catalyst layer of Pt3Cr/C so that oxidation at the cathode of methanol that crosses from the anode through the membrane to the cathode is reduced with a concomitant increase of net electrical potential at the cathode electrode.
FILED Friday, September 27, 2002
APPL NO 10/260780
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/19
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US 07101643 Kerr et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) John Borland Kerr (Oakland, California);  Shanger Wang (Fairfield, California);  Jun Hou (Painted Post, New York);  Steven Edward Sloop (Berkeley, California);  Yong Bong Han (Berkeley, California);  Gao Liu (Oakland, California)
ABSTRACT New polymer electrolytes were prepared by in situ cross-linking of allyl functional polymers based on hydrosilation reaction using a multifunctional silane cross-linker and an organoplatinum catalyst. The new cross-linked electrolytes are insoluble in organic solvent and show much better mechanical strength. In addition, the processability of the polymer electrolyte is maintained since the casting is finished well before the gel formation.
FILED Friday, May 31, 2002
APPL NO 10/160604
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/313
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US 07101718 Weiss et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Shimon Weiss (Pinole, California);  Marcel Bruchez, Jr. (Albany, California);  Paul Alivisatos (Oakland, California)
ABSTRACT A semiconductor nanocrystal compound is described capable of linking to an affinity molecule. The compound comprises (1) a semiconductor nanocrystal capable of emitting electromagnetic radiation and/or absorbing energy, and/or scattering or diffracting electromagnetic radiation—when excited by an electromagnetic radiation source or a particle beam; and (2) at least one linking agent, having a first portion linked to the semiconductor nanocrystal and a second portion capable of linking to an affinity molecule. The compound is linked to an affinity molecule to form a semiconductor nanocrystal probe capable of bonding with a detectable substance. subsequent exposure to excitation energy will excite the semiconductor nanocrystal in the probe causing the emission of electromagnetic radiation. Further described are processes for respectively: making the luminescent semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and using the probe to determine the presence of a detectable substance in a material.
FILED Thursday, August 12, 2004
APPL NO 10/918622
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/524
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US 07102321 Edwards et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) John Edwards (Kent, Washington);  Longya Xu (Dublin, Ohio);  Brij B. Bhargava (Santa Barbara, California)
ABSTRACT A method for driving a neutral point-clamped multi-level voltage source inverter supplying a synchronous motor is provided. A DC current is received at a neutral point-clamped multi-level voltage source inverter. The inverter has first, second, and third output nodes. The inverter also has a plurality of switches. A desired speed of a synchronous motor connected to the inverter by the first second and third nodes is received by the inverter. The synchronous motor has a rotor and the speed of the motor is defined by the rotational rate of the rotor. A position of the rotor is sensed, current flowing to the motor out of at least two of the first, second, and third output nodes is sensed, and predetermined switches are automatically activated by the inverter responsive to the sensed rotor position, the sensed current, and the desired speed.
FILED Tuesday, December 31, 2002
APPL NO 10/335804
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Motive power systems
318/801
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US 07102356 Wild
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Caterpillar Inc. (Peoria, Illinois)
INVENTOR(S) Arthur Wild (Chillicothe, Illinois)
ABSTRACT A method is provided for detecting electrical leakage between a power supply and a frame of a vehicle or machine. The disclosed method includes coupling a first capacitor between a frame and a first terminal of a power supply for a predetermined period of time. The current flowing between the frame and the first capacitor is limited to a predetermined current limit. It is determined whether the voltage across the first capacitor exceeds a threshold voltage. A first output signal is provided when the voltage across the capacitor exceeds the threshold voltage.
FILED Tuesday, December 23, 2003
APPL NO 10/742884
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/510
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US 07102459 Arnold et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Calabazas Creek Research, Inc. (Saratoga, California)
INVENTOR(S) Möbius Arnold (Eggenstein, Germany);  Robert Lawrence Ives (Saratoga, California)
ABSTRACT A power combiner for the combining of symmetric and asymmetric traveling wave energy comprises a feed waveguide having an input port and a launching port, a reflector for reflecting launched wave energy, and a final waveguide for the collection and transport of launched wave energy. The power combiner has a launching port for symmetrical waves which comprises a cylindrical section coaxial to the feed waveguide, and a launching port for asymmetric waves which comprises a sawtooth rotated about a central axis.
FILED Monday, December 15, 2003
APPL NO 10/733883
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/125
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US 07102751 Harper
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Warren W. Harper (Benton City, Washington)
ABSTRACT One embodiment of the present invention includes: a modulated laser light source to transmit an interrogation light beam to a region including a substance for spectroscopic evaluation, a detector responsive to modulated light from the region to provide a corresponding modulated signal, and a signal processing subsystem responsive to the modulated signal to generate a spectroscopic absorption peak representation. This subsystem also estimates absorbance based on a derivative form of an absorption peak and a residual amplitude modulation level corresponding to the absorption peak.
FILED Friday, September 10, 2004
APPL NO 10/938967
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/437
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US 07103402 Vo-Dinh
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Tuan Vo-Dinh (Knoxville, Tennessee)
ABSTRACT A diagnostic method and associated system includes the steps of exposing at least one sample location with excitation radiation through a single optical waveguide or a single optical waveguide bundle, wherein the sample emits emission radiation in response to the excitation radiation. The same single optical waveguide or the single optical waveguide bundle receives at least a portion of the emission radiation from the sample, thus providing co-registration of the excitation radiation and the emission radiation. The wavelength of the excitation radiation and emission radiation is synchronously scanned to produce a spectrum upon which an image can be formed. An increased emission signal is generated by the enhanced overlap of the excitation and emission focal volumes provided by co-registration of the excitation and emission signals thus increasing the sensitivity as well as decreasing the exposure time necessary to obtain an image.
FILED Thursday, October 02, 2003
APPL NO 10/677703
ART UNIT 3768 — Optics
CURRENT CPC
Surgery
6/476
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National Science Foundation (NSF) 

US 07101044 Fink
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Wolfgang Fink (Montrose, California)
ABSTRACT A method and apparatus for electronically performing a visual field test for a patient. A visual field test pattern is displayed to the patient on an electronic display device and the patient's responses to the visual field test pattern are recorded. A visual field representation is generated from the patient's responses. The visual field representation is then used as an input into a variety of automated diagnostic processes. In one process, the visual field representation is used to generate a statistical description of the rapidity of change of a patient's visual field at the boundary of a visual field defect. In another process, the area of a visual field defect is calculated using the visual field representation. In another process, the visual field representation is used to generate a statistical description of the volume of a patient's visual field defect.
FILED Monday, May 05, 2003
APPL NO 10/430367
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Optics: Eye examining, vision testing and correcting
351/211
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US 07101053 Parker
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Astronomical Sciences (AST)
National Radio Astronomy Observatory (NRAO)
Federally Funded Research and Development Center (FFRDC)
Operated by Associated Universities, Inc. (AUI)at Charlottesville, VA
APPLICANT(S)
ASSIGNEE(S) Associated Universities, Inc. (Washington, District of Columbia)
INVENTOR(S) David H. Parker (Earlysville, Virginia)
ABSTRACT Multidirectional retroreflectors and methods of reflecting light beams from multiple directions are provided. The multidirectional retroreflectors utilize a four-mirror retroreflector with a common virtual reflection point.
FILED Thursday, August 12, 2004
APPL NO 10/916612
ART UNIT 2873 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Optical: Systems and elements
359/529
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US 07102047 Grubbs et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Robert H. Grubbs (S. Pasadena, California);  Peter Schwab (Bad Durkheim, Germany);  Sonbinh T. Nguyen (Evanston, Illinois)
ABSTRACT Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene compounds are of the formula
where M is Os or Ru; R1 is hydrogen; R is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, and substituted or unsubstituted aryl; X and X1 are independently selected from any anionic ligand; and L and L1 are independently selected from any neutral electron donor. The ruthenium and osmium carbene compounds of the present invention may be synthesized using diazo compounds, by neutral electron donor ligand exchange, by cross metathesis, using acetylene, using cumulated olefins, and in a one-pot method using diazo compounds and neutral electron donors. The ruthenium and osmium carbene compounds of the present invention may be used to catalyze olefin metathesis reactions including, but not limited to, ROMP, RCM, depolymerization of unsaturated polymers, synthesis of telechelic polymers, and olefin synthesis.
FILED Monday, October 18, 2004
APPL NO 10/968361
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Chemistry of hydrocarbon compounds
585/511
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US 07102059 Collmer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York);  Board of Regents University and Community College System of Nevada, on Behalf of the University of Nevada, Las Vegas (Las Vegas, Nevada);  University of Nebraska at Lincoln (Lincoln, Nebraska)
INVENTOR(S) Alan Collmer (Ithaca, New York);  James R. Alfano (Lincoln, Nebraska);  Amy O. Charkowski (Madison, Wisconsin)
ABSTRACT One aspect of the present invention relates to isolated nucleic acid molecules (i) encoding proteins or polypeptides of Pseudomonas CEL and EEL genomic regions, (ii) nucleic acid molecules which hybridize thereto under stringent conditions, or (iii) nucleic acid molecules that include a nucleotide sequence which is complementary to the nucleic acid molecules of (i) and (ii). Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The nucleic acid molecules and proteins of the present invention can be used to imparting disease resistance to a plant, making a plant hypersusceptible to colonization by nonpathogenic bacteria, causing eukaryotic cell death, and treating cancerous conditions.
FILED Friday, July 16, 2004
APPL NO 10/893776
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/298
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US 07102656 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Jung-Hyurk Lim (Evanston, Illinois)
ABSTRACT A method of nanolithography includes transporting a patterning compound from a nanoscopic tip to a substrate to form a pattern on the substrate. The patterning compound has a first electrostatic charge and the substrate has a second electrostatic charge which is opposite to the first electrostatic charge. The patterning compound can be an electrically conductive polymer having a charged polymer backbone. The patterns can be dots and lines having lateral dimensions of less than one micron. No electrical bias from an external voltage source between the tip and the substrate is needed.
FILED Wednesday, May 21, 2003
APPL NO 10/442188
ART UNIT 2861 — Printing/Measuring and Testing
CURRENT CPC
Recorders
346/140.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07103522 Shepard
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Kenneth Shepard (Ossining, New York)
ABSTRACT Techniques for estimating a body voltage of one or more transistors which form digital partially depleted silicon-on-insulator circuit, and for using estimated voltages to analyze electrical properties of the circuit, are disclosed. In one technique, device models are obtained and abstracted to generate simplified electrical descriptions of the transistors. The circuit topology is checked to generate sets of accessible states for the transistors that are indicative of whether a connection between a source or a drain of a transistor and either a power supply or ground exists. Next, sets of reference state body voltage minima and reference state body voltage maxima are determined for each of the transistors based on corresponding simplified electrical descriptions and corresponding sets of accessible states. Finally, a target state body voltage minima and a target state body voltage maxima are ascertained, one for each transistor, based on the determined sets of reference state body voltage minima and reference state body voltage maxima.
FILED Friday, June 09, 2000
APPL NO 09/591270
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE39270 Bentley et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Maryland Biotechnology Institute (Baltimore, Maryland)
INVENTOR(S) William E. Bentley (Annapolis, Maryland);  Hyung Joon Cha (Pohang, South Korea);  Minh-Quan Pham (North Bethesda, Maryland);  Rita Khanna (North Bethsda, Maryland)
ABSTRACT The present invention provides for a recombinant insect larvae and a process of manufacturing proteins utilizing insect larvae that allows for the selection of individual larvae for harvest at the point of their optimal expression of a protein of interest. This invention also provides for a process to manufacture proteins in larvae that does not require synchronization of the infection, growth and harvest larvae to optimally manufacture a protein of interest. The invention further provides for a process of producing interleukin-2 in larvae.
FILED Friday, September 14, 2001
APPL NO 09/952668
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/4
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07101044 Fink
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Wolfgang Fink (Montrose, California)
ABSTRACT A method and apparatus for electronically performing a visual field test for a patient. A visual field test pattern is displayed to the patient on an electronic display device and the patient's responses to the visual field test pattern are recorded. A visual field representation is generated from the patient's responses. The visual field representation is then used as an input into a variety of automated diagnostic processes. In one process, the visual field representation is used to generate a statistical description of the rapidity of change of a patient's visual field at the boundary of a visual field defect. In another process, the area of a visual field defect is calculated using the visual field representation. In another process, the visual field representation is used to generate a statistical description of the volume of a patient's visual field defect.
FILED Monday, May 05, 2003
APPL NO 10/430367
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Optics: Eye examining, vision testing and correcting
351/211
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07103615 Moffatt
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Christopher L. Moffatt (Orlando, Florida)
ABSTRACT The distributed system includes a database server, an administration module, a process evaluation module, and a data display module. The administration module is in communication with the database server for providing observation criteria information to the database server. The process evaluation module is in communication with the database server for obtaining the observation criteria information from the database server and collecting process data based on the observation criteria information. The process evaluation module utilizes a personal digital assistant (PDA). A data display module in communication with the database server, including a website for viewing collected process data in a desired metrics form, the data display module also for providing desired editing and modification of the collected process data. The connectivity established by the database server to the administration module, the process evaluation module, and the data display module, minimizes the requirement for manual input of the collected process data.
FILED Tuesday, July 23, 2002
APPL NO 10/201730
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/104.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07102059 Collmer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York);  Board of Regents University and Community College System of Nevada, on Behalf of the University of Nevada, Las Vegas (Las Vegas, Nevada);  University of Nebraska at Lincoln (Lincoln, Nebraska)
INVENTOR(S) Alan Collmer (Ithaca, New York);  James R. Alfano (Lincoln, Nebraska);  Amy O. Charkowski (Madison, Wisconsin)
ABSTRACT One aspect of the present invention relates to isolated nucleic acid molecules (i) encoding proteins or polypeptides of Pseudomonas CEL and EEL genomic regions, (ii) nucleic acid molecules which hybridize thereto under stringent conditions, or (iii) nucleic acid molecules that include a nucleotide sequence which is complementary to the nucleic acid molecules of (i) and (ii). Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The nucleic acid molecules and proteins of the present invention can be used to imparting disease resistance to a plant, making a plant hypersusceptible to colonization by nonpathogenic bacteria, causing eukaryotic cell death, and treating cancerous conditions.
FILED Friday, July 16, 2004
APPL NO 10/893776
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/298
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07102017 Liu et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Stamford, Connecticut)
INVENTOR(S) Ping Liu (Mississauga, Canada);  Yiliang Wu (Mississauga, Canada);  Beng S. Ong (Mississauga, Canada);  Maria Birau (Mississauga, Canada)
ABSTRACT A process composed of subjecting a reaction mixture comprising a reaction medium, a coupling agent, and a precursor to a coupling temperature to preferentially form a desired small molecular thiophene compound in a single-step synthesis, wherein the precursor consists of: (i) an optional divalent linkage, and (ii) a plurality of thiophene units, each thiophene unit being represented by structure (A)
wherein each thiophene unit is bonded at either or both of the second ring position and the fifth ring position.
FILED Thursday, June 10, 2004
APPL NO 10/865029
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
549/59
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07103782 Tugenberg et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) Motorola, Inc. (Schaumburg, Illinois)
INVENTOR(S) Steven R. Tugenberg (Scottsdale, Arizona);  Douglas A. Hardy (Scottsdale, Arizona);  Thomas E. Tkacik (Phoenix, Arizona)
ABSTRACT A secure memory and processing system is disclosed for use in various types of communication devices. The secure processing system provides for the encryption and storage of sensitive data in a storage medium external to the secure processing system. The encrypted data is decrypted with encryption logic circuitry within the secure memory and transferred to a zeroizable memory for use by a host processor. The secure memory uses a laser-scribed encryption key coupled to encryption logic circuitry within the secure memory for encrypting and decrypting the sensitive information.
FILED Wednesday, September 27, 2000
APPL NO 09/671949
ART UNIT 2132 — Memory Access and Control
CURRENT CPC
Electrical computers and digital processing systems: Support
713/194
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07100444 Challoner
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) A. Dorian Challoner (Manhattan Beach, California)
ABSTRACT The present invention discloses a resonator gyroscope comprising a resonator including two bodies, each with a center of mass and transverse inertia symmetry about an axis that are substantially coincident and each supported by one or more elastic elements and wherein the bodies together forming two differential rocking modes of vibration transverse to the axis with substantially equal frequencies and wherein the two bodies transfer substantially no net momentum to the baseplate when the resonator is excited. The gyroscope further includes a baseplate affixed to the resonator by the one or more elastic elements.
FILED Wednesday, April 02, 2003
APPL NO 10/405178
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/504.20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07100752 Reid et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Safety By Design Co. (Lincoln, Nebraska)
INVENTOR(S) John D. Reid (Lincoln, Nebraska);  John R. Rohde (Lincoln, Nebraska);  Dean L. Sicking (Lincoln, Nebraska);  King K. Mak (San Antonio, Texas)
ABSTRACT A crash cushion system to envelop at least one bridge pier. The system has two impact heads, one facing one traffic flow direction and the other facing an opposite traffic flow direction. The heads are connected to multi-stage box beam energy absorbers which are in turn connected to a tubular frame structure which envelops the bridge piers. The frame is spaced apart from the face of the pier sufficiently to avoid an impacting vehicle's snagging the frame and contacting the pier structure. Anchorage cables to stiffen and support the sides of the envelope are positioned inside the frame's parallelogram shape.
FILED Thursday, September 02, 2004
APPL NO 10/933045
ART UNIT 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Brakes
188/371
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE39267 Benish et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Michele A. Benish (Pearland, Texas);  Michael Lawless (St. Charles, Missouri);  Raymond J. A. Budde (Bellaire, Texas)
ABSTRACT Various thienopyrimidine-based analog compounds that selectively inhibit the Src family of tyrosine kinases. These compounds are thienopyrimidines and contain a hydrozone bridge created by heating a thienopyrimidine hydrazine with an aldehyde in ethanol at reflux. Such compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.
FILED Monday, June 28, 2004
APPL NO 10/878140
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/260.100
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, September 05, 2006.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060905.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital