FedInvent™ Patents

Patent Details for Tuesday, September 12, 2006 

This page was updated on Sunday, March 26, 2023 at 08:05 PM GMT

Department of Health and Human Services (HHS) 

US 07105149 Dalla-Favera
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Riccardo Dalla-Favera (New York, New York)
ABSTRACT This invention provides an isolated nucleic acid molecule which encodes immunoglobulin receptor, Immunoglobulin superfamily Receptor Translocation Associated, IRTA, protein. Provided too, are the IRTA proteins encoded by the isolated nucleic acid molecules, IRTA1, IRTA2, IRTA3, IRTA4 or IRTA5 proteins, having the amino acid sequences set forth in any of FIGS. 18A, 18B-1–18B-3, 18C-1–18C-2, 18D-1–18D-2 or 18E-1–18E-2. Oligonucleotides of the isolated nucleic acid molecules are provided. Antibodies directed to an epitope of a purified IRTA1, IRTA2, IRTA3, IRTA4 or IRTA5 proteins are also provided, as are pharmaceutical compositions comprising such antibodies or oligonucleotides. Methods for detecting a B cell malignancy in a sample from a subject; diagnosing B cell malignancy in a sample from a subject; detecting human IRTA protein in a sample; and treating a subject having a B cell cancer are also provided.
FILED Tuesday, November 28, 2000
APPL NO 09/724254
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.490
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US 07105156 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Canji, Inc. (Kenilworth, New Jersey)
INVENTOR(S) Wen-Hwa Lee (San Antonio, Texas);  H. Michael Shepard (Encinitas, California);  Richard J. Gregory (Westford, Massachusetts);  Ken N. Wills (Encinitas, California);  Daniel C. Maneval (San Diego, California);  Eva Lee (San Antonio, Texas);  David Goodrich (East Aurora, New York);  Nan-Ping Wang (Bellevue, Washington)
ABSTRACT Disclosed are methods of controlling cell cycle progression by introducing into a cell to be controlled a composition selected from the group consisting of p56RB protein, a fragment of the p56RB protein, and the gene encoding p56RB protein to alter the cell cycle progression while maintaining the viability of the cell. The p56RB protein has been found to have the unexpected and surprising characteristic of being soluble in low concentrations of glycerol, thereby enhancing its value in pharmaceutical applications and the gene encoding p56RB when delivered to the hyperproliferating cell inhibits cellular proliferation.
FILED Wednesday, June 07, 1995
APPL NO 08/472760
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
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US 07105159 Israeli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S) Ron S. Israeli (Staten Island, New York);  Warren D. W. Heston (New York, New York);  William R. Fair (New York, New York)
ABSTRACT This invention provides purified antibodies to the outer membrane domain of prostate-specific membrane (PSM) antigen, compositions of matter comprising PSM antigen antibodies conjugated to a radioisotope or a toxin, and a method of imaging prostate cancer by using PSM antigen antibodies.
FILED Tuesday, June 06, 1995
APPL NO 08/470735
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/138.100
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US 07105169 Boyd
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Michael R Boyd (Ijamsville, Maryland)
ABSTRACT The present invention provides, among other things, methods of removing virus from a sample, a composition comprising a solid support matrix to which is attached a cyanovirin, a conjugate comprising a cyanovirin coupled to at least one effector component, a composition comprising such a conjugate, methods of inhibiting prophylactically or therapeutically a viral infection of a host, and a matrix-anchored anti-cyanovirin antibody.
FILED Wednesday, September 12, 2001
APPL NO 09/951189
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/234.100
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US 07105170 Quinn et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Frederick D. Quinn (Avondale Estates, Georgia);  Kristin A. Birkness (Atlanta, Georgia);  Manon Deslauriers (Quebec City, Canada);  Peter King (Nacogdoches, Texas);  David S. Beall (Atlantic Beach, Florida)
ABSTRACT Provided herein is an in vitro granuloma model and methods of its use. Methods of detecting and/or diagnosing latent tuberculosis in a subject are also provided, as are latency-specific antigens (and antibodies thereto), such as α-crystallin, and methods of identifying and using such molecules. Also provided are immunostimulatory compositions, for instance for use in eliciting an immune response in a subject, such as an immune response to a latent tuberculosis infection. Kits for carrying out the provided methods are also described.
FILED Monday, January 07, 2002
APPL NO 10/250930
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/248.100
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US 07105171 Stephens et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard S. Stephens (Orinda, California);  Diane Kawa (Albany, California)
ABSTRACT The present invention features peptides of a PorB polypeptide, which PorB peptides are useful in production of antibodies that bind the full-length PorB polypeptide and as a therapeutic agent. In specific embodiments the invention features a composition comprising one or more PorB peptides (other than a full-length PorB polypeptide), which peptides contain at least one epitope that can elicit Chlamydia-neutralizing antibodies. The invention also features methods for induction of a protective immune response against infection by Chlamydia and Chlamydiophila.
FILED Thursday, March 07, 2002
APPL NO 10/094407
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/263.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105183 McGrath
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael S. McGrath (Burlingame, California)
ABSTRACT The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation. The invention also features methods of monitoring therapy by assessing blood immune cell activation before and after therapy.
FILED Monday, January 24, 2005
APPL NO 11/042816
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/661
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US 07105274 Burstyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Judith N. Burstyn (Madison, Wisconsin);  Arthur B. Ellis (Falls Church, Virginia);  Omar Green (Madison, Wisconsin);  Nickolaus A. Smith (Madison, Wisconsin)
ABSTRACT A photoluminescent polymer/transition metal complex is disclosed which is capable of selectively binding to alkenes to thereby alter the photoluminescence of the complex. In one embodiment, a poly(vinyl phenyl ketone)/Ag(I) complex is disclosed which reversibly and selectively binds with ethylene. The disclosed photoluminescent polymer/transition metal complex can be used as part of a sensor to determine the presence and/or concentration of alkenes such as ethylene.
FILED Wednesday, June 02, 2004
APPL NO 10/859484
ART UNIT 1752 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/270.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105293 Ramaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Sridhar Ramaswamy (Brookline, Massachusetts);  Todd R. Golub (Newton, Massachusetts);  Pablo Tamayo (Cambridge, Massachusetts);  Michael Angelo (San Francisco, California)
ABSTRACT Sets of genetic markers for specific tumor classes are described, as well as methods of identifying a biological sample based on these markers. Also described are diagnostic, prognostic, and therapeutic screening uses for these markers, as well as oligonucleotide arrays comprising these markers.
FILED Wednesday, September 19, 2001
APPL NO 09/955920
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07105306 Clevenger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Charles Clevenger (Merion Station, Pennsylvania);  Michael A. Rycyzyn (Paoli, Pennsylvania)
ABSTRACT Compositions containing cyclophilin B, mutants of cyclophilin B or inhibitors of cyclophilin B and methods of using these compositions to modulate somatolactogenic function are provided.
FILED Thursday, August 10, 2000
APPL NO 10/049562
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
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US 07105310 Gray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Harry B. Gray (Pasadena, California);  Brian R. Crane (Ithaca, New York);  Jay R. Winkler (Pasadena, California);  Ivan Julian Dmochowski (Philadelphia, Pennsylvania);  Jonathan J. Wilker (LaFayette, Indiana);  Alexander Robert Dunn (Colorado Springs, Colorado)
ABSTRACT Methods and compositions for detecting and characterizing target biomolecules using sensitizer-linked substrate molecules are disclosed. High throughput screening assays and therapeutic applications of the inventions are also included
FILED Wednesday, July 19, 2000
APPL NO 10/031532
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.400
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US 07105328 Wood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Dana-Farber Cancer Institute (Boston, Massachusetts);  Wyeth (Madison, New Jersey)
INVENTOR(S) Clive Wood (Boston, Massachusetts);  Gordon J. Freeman (Brookline, Massachusetts);  Divya Chaudhary (Andover, Massachusetts)
ABSTRACT Disclosed are screening assays for identifying compounds which modulate the activity of, or signaling via, B7-4, or PD-1, especially which modulate the binding of B7-4 or PD-1 to a target molecule Further disclosed are a vaccine and also other compositions which contain agents that modulate signaling via PD-1.
FILED Tuesday, April 02, 2002
APPL NO 10/115615
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/194
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US 07105330 Stern et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert Stern (San Francisco, California);  Gregory I. Frost (San Francisco, California);  Anthony Csoka (San Francisco, California);  Tim M. Wong (San Francisco, California)
ABSTRACT The invention is based on the discovery of methods for purification of an acid active hyaluronidase found in human plasma (hpHAse), including both biochemical and immunoaffinity purification methods. The method of immunoaffinity purification of the invention is based on the discovery of a method for identifying antibodies that specifically bind native hpHAse (anti-native hpHAse antibodies), and anti-native hpHAse antibodies identified by this screening method. The invention also features an assay for sensitive detection of HAse activity using biotinylated hyaluronic acid (bHA). Purification and characterization of hpHAse lead to the inventors' additional discovery that hpHAse is encoded by the LuCa-1 gene, which gene is present in the human chromosome at 3p21.3, a region associated with tumor suppression. The invention additionally features methods of treating tumor-bearing patients by administration of hpHAse and/or transformation of cells with hpHAse-encoding DNA.
FILED Friday, July 18, 2003
APPL NO 10/622283
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105334 Pojasek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Kevin Pojasek (Boston, Massachusetts);  Rahul Raman (Cambridge, Massachusetts);  Ram Sasisekharan (Lincoln, Massachusetts)
ABSTRACT The invention relates to rationally designed polysaccharide lyases and uses thereof. In particular, the invention relates to modified chondroitinase B. The modified chondroitinase B enzymes of the invention are useful for a variety of purposes, including cleaving and sequencing polysaccharides such as glycosaminoglycans (GAGs) as well as removing polysaccharides from a solution. The invention also includes methods of inhibiting anticoagulant activity, inhibiting angiogenesis, treating cancer, and inhibiting maternal malarial infection.
FILED Thursday, October 14, 2004
APPL NO 10/967041
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/232
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105343 Fraser, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) University of Notre Dame du Lac (Notre Dame, Indiana)
INVENTOR(S) Malcolm J. Fraser, Jr. (Granger, Indiana);  Xu Li (Notre Dame, Indiana)
ABSTRACT The present invention provides efficient transfer of genes into host cells or embryos to transform the cells or embryos by transposition vectors using the minimal amount of nucleotide sequences in the transposon piggyBac required for gene transfer. The transformed cells or embryos may also be developed into transgenic organisms.
FILED Monday, April 19, 2004
APPL NO 10/826523
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105345 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) James M. Wilson (Gladwyne, Pennsylvania);  Weidong Xiao (Jenkintown, Pennsylvania)
ABSTRACT The nucleic acid sequences of adeno-associated virus (AAV) serotype 1 are provided, as are vectors and host cells containing these sequences and functional fragments thereof. Also provided are methods of delivering genes via AAV-1 derived vectors.
FILED Wednesday, October 29, 2003
APPL NO 10/696282
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 07105352 Asher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh (Pittsburgh, Pennsylvania)
INVENTOR(S) Sanford A. Asher (Pittsburgh, Pennsylvania);  Vladimir L. Alexeev (Pittsburgh, Pennsylvania);  Igor K. Lednev (Pittsburgh, Pennsylvania);  Anjal C. Sharma (Pittsburgh, Pennsylvania);  Craig Wilcox (Pittsburgh, Pennsylvania)
ABSTRACT The present invention is related to glucose sensors that are capable of detecting the concentration or level of glucose in a solution or fluid having either low or high ionic strength. The glucose sensors of the present invention comprise a polymerized crystalline colloidal array (PCCA) and a molecular recognition component capable of responding to glucose. The molecular recognition component may be a boronic acid, such as a phenylboronic acid, glucose oxidase, a combination of phenylboronic acid and poly(ethylene)glycol or crown ether, or another component capable of detecting glucose in various fluids and solutions. The glucose sensors of the present invention may be useful in the development of noninvasive or minimally invasive in vivo glucose sensors for patients having diabetes mellitus.
FILED Monday, July 01, 2002
APPL NO 10/189107
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/94
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US 07105488 Tarasova et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Nadya I. Tarasova (Frederick, Maryland);  Christopher J. Michejda (North Potomac, Maryland)
ABSTRACT G-protein coupled receptors (GPCR) generally contain seven transmembrane helices. The present invention provides synthetic peptides derived from these transmembrane helices. The peptides inhibit GPCR function by disrupting GPCR structure. In certain embodiments, charged residues are added at one terminus to promote correct orientation of the peptide in the membrane.
FILED Friday, February 26, 1999
APPL NO 09/601600
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/16
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US 07105491 Shen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S) Ben Shen (Verona, Wisconsin);  Wen Liu (Madison, Wisconsin)
ABSTRACT This invention provides nucleic acid sequences and characterization of the gene cluster responsible for the biosynthesis of the enediyne C-1027 (produced by Streptomyces globisporus). Methods are provided for the biosynthesis of enediynes, enediyne analogs and other biological molecules. This invention also provides enediyne and enediyne analogs biosynthesized by manipulation of the C-1027 gene pathway.
FILED Tuesday, November 12, 2002
APPL NO 10/292198
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/25
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US 07105496 Bouck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Noël P. Bouck (Occidental, California);  David W. Dawson (Los Angeles, California);  Paul R. Gillis (Chicago, Illinois);  Olga Volpert (Wilmette, Illinois);  Susan E. Crawford (Burr Ridge, Illinois);  Veronica M. Stellmach (Chicago, Illinois)
ABSTRACT The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous PEDF to cells associated with the tissue. The presence of exogenous PEDF inhibits angiogenesis within the tissue, in part by interfering with the ability of vascular endothelia to expand within the tissue. The invention also provides a method for determining the severity of a tumor be assaying for the presence of PEDF within the tumor. To facilitate the inventive methods, the present invention provides pharmaceutical compositions including sources of PEDF.
FILED Wednesday, June 25, 2003
APPL NO 10/603387
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07105502 Arnold et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ernst V Arnold (Hagerstown, Maryland);  Larry K Keefer (Bethesda, Maryland);  Joseph A Hrabie (Frederick, Maryland)
ABSTRACT The invention provides NO- or NO-releasing imidate; and thioimidate, diazeniumdiolates, in which the N2O2 functional group is bonded to a carbon atom. The imidate and thioimidate diazeniumdiolates are bound to a polymer or a substrate.
FILED Thursday, November 06, 2003
APPL NO 10/702849
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/149
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US 07105511 Laskin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey);  Rutgers, the State University (New Brunswick, New Jersey);  Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S) Jeffrey D. Laskin (Piscataway, New Jersey);  Ned Heindel (Easton, Pennsylvania);  Diane Heck (Rumson, New Jersey);  Anna Marie Vetrano (North Brunswick, New Jersey);  Christophe Guillon (Bethlehem, Pennsylvania);  Peter DeMatteo (Allentown, Pennsylvania)
ABSTRACT Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.
FILED Thursday, August 19, 2004
APPL NO 10/922300
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/222.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105560 Carson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of California (Oakland, California)
INVENTOR(S) Dennis A. Carson (Del Mar, California);  Howard B. Cottam (Escondido, California);  Souchi Adachi (La Jolla, California);  Lorenzo M. Leoni (San Diego, California)
ABSTRACT A method of treating multiple myeloma (MM) is provided comprising administering an amount of etodolac to a subject afflicted with MM that is effective to selectively reduce the viability of and/or to sensitize the cancer cells to an anti-cancer agent.
FILED Wednesday, June 07, 2000
APPL NO 09/589476
ART UNIT 1614 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/411
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US 07105561 Carson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of California (Oakland, California)
INVENTOR(S) Dennis A. Carson (Del Mar, California);  Howard B. Cottam (Escondido, California);  Souchi Adachi (La Jolla, California);  Lorenzo M. Leoni (San Diego, California)
ABSTRACT A method of treating cancer is provided comprising administering an amount of etodolac to a subject afflicted with cancer that is effective to reduce the viability and/or to sensitize the cancer to an anti-cancer agent.
FILED Thursday, September 05, 2002
APPL NO 10/236221
ART UNIT 1614 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/411
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US 07105637 Shackleton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas);  Children's Hospital and Research Center at Oakland (Oakland, California)
INVENTOR(S) Cedric Shackleton (Oakland, California);  Li-Wei Guo (Houston, Texas);  William K. Wilson (Houston, Texas)
ABSTRACT The invention provides isolated dehydro-estriol (8-DHE3) and dehydro-pregnanetriol (7-DHPT), and methods of their synthesis. These compounds are useful in diagnosis of Smith-Lemli-Optiz syndrome (SLOS).
FILED Friday, February 14, 2003
APPL NO 10/367096
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
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US 07105641 Charo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Israel R. Charo (San Francisco, California);  Shaun R. Coughlin (Tiburon, California)
ABSTRACT Novel human chemokine receptors, MCP-1RA and MCP-1RB, and processes for producing them are disclosed. The receptors, which are alternately spliced versions of MCP-1 receptor protein may be used in an assay to identify antagonists of MCP-1 which are therapeutically useful in the treatment of atherosclerosis and other diseases characterized by monocytic infiltrates.
FILED Monday, March 01, 2004
APPL NO 10/791592
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105647 Bradfield et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Christopher A. Bradfield (Madison, Wisconsin);  Yi Zhong Gu (Sunnyvale, California);  John B. Hogenesch (San Diego, California)
ABSTRACT The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These “MOPs” (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are α-class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.
FILED Friday, November 27, 1998
APPL NO 09/555362
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105656 Colgan
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Sean P. Colgan (North Reading, Massachusetts)
ABSTRACT Methods and compositions are provided for treating a subject having or at risk of developing a hematologic malignancy and/or multiple drug resistance.
FILED Thursday, October 25, 2001
APPL NO 10/007255
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/24.330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105657 Batra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Surinder K. Batra (Omaha, Nebraska);  Ajay P. Singh (Omaha, Nebraska);  Nicolas Moniaux (Omaha, Nebraska)
ABSTRACT Methods are provided for the inhibition of metastasis of cancer cells expressing MUC4, metastatic pancreatic cancer cells.
FILED Friday, November 08, 2002
APPL NO 10/291151
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105675 Ananthan
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S)
ASSIGNEE(S) Southern Research Institute (Birmingham, Alabama)
INVENTOR(S) Subramaniam Ananthan (Birmingham, Alabama)
ABSTRACT Compounds represented by the formulae:
wherein each of Y, X and R individually is selected from the group consisting of hydrogen, hydroxy, halo, CF3, NO2, CN, NH2, COR1 and CO2R2 wherein R1 is selected from the group consisting of alkyl, aryl, alkaryl, and NH2, and R2 is selected from the group consisting of alkyl, aryl and aralkyl, and provided that at least one of Y, X and R is other than H; and pharmaceutically acceptable salts thereof are provided. Compounds of the above formula are useful as analgesics for treating pain, as immunomodulators and for treating drug abuse.
FILED Thursday, October 27, 2005
APPL NO 11/259073
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105678 Meltzer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S)
ASSIGNEE(S) Organix, Inc. (Woburn, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Peter C. Meltzer (Lexington, Massachusetts);  Paul Blundell (Somerville, Massachusetts);  Bertha C. Madras (Newton, Massachusetts)
ABSTRACT Radiopharmaceutical compounds are disclosed. A tropane compound is linked through the N atom at the 8-position to a chelating ligand capable of complexing technetium or rhenium to produce a neutral labeled complex that selectively binds to the dopamine transporter over the serotonin transporter with a ratio of 10 or more. These compounds can be prepared as separate diastereoisomers as well as a mixture of diastereoisomers. Also disclosed are radiopharmaceutical kits for preparing the labeled radiopharmaceutical compounds.
FILED Thursday, October 11, 2001
APPL NO 09/975586
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/132
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105680 O'Halloran et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Thomas V. O'Halloran (Wilmette, Illinois);  Masayasu Taki (Evanston, Illinois)
ABSTRACT Benzoxazole fluorescent sensor compounds and related ratiometric imaging methods for zinc metal ion.
FILED Thursday, July 08, 2004
APPL NO 10/887465
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/271.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105695 Pettit et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents, acting for and on behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S) George R. Pettit (Paradise Valley, Arizona);  Bryan R. Moser (Tempe, Arizona)
ABSTRACT The original synthesis of combretastatin A-2 (1a) was modified to provide an efficient scale-up procedure for obtaining this antineoplastic stilbene. Subsequent conversion to a useful prodrug was accomplished by phosphorylation employing in situ formation of dibenzylchlorophosphite followed by cleavage of the benzyl ester protective groups with bromotrimethylsilane to afford phosphoric acid intermediate 11. The latter was immediately treated with sodium methoxide to complete a practical route to the disodium phosphate prodrug (2a). The phosphoric acid precursor (11) of phosphate 2a was employed in a parallel series of reactions to produce a selection of metal and ammonium cation prodrug candidates. Each of the phosphate salts (2a–q) was evaluated with respect to relative solubility behavior, cancer cell growth inhibition, and antimicrobial activity.
FILED Friday, December 20, 2002
APPL NO 10/499848
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
558/114
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106891 Wyman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Library of Medicine (NLM)
APPLICANT(S)
ASSIGNEE(S) Insightful Corporation (Seattle, Washington)
INVENTOR(S) Bradley Wyman (Kirkland, Washington);  Lydia Ng (Seattle, Washington)
ABSTRACT Computer-based methods and systems for automatically determining convergence when registering image sets are provided. Example embodiments provide an Enhanced Image Registration System (EIRS), which includes an Image Comparison Module, a Transformation Optimizer, and a Convergence Calculator. When the EIRS receives two image sets to align, the Image Comparison Module compares two image sets to determine or measure how closely the image sets are aligned. The Transformation Optimizer determines an appropriate transformation to apply to one of the image sets to align it with the reference image set. The Transformation Optimizer then applies the determined transformation. The Convergence Calculator examines one or more points within the transformed image set to determine when convergence is attained.
FILED Thursday, May 16, 2002
APPL NO 10/063834
ART UNIT 2627 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 07103949 Rife et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jack C. Rife (Washington, District of Columbia);  Michael I. Bell (Rockville, Maryland);  James Horwitz (Fairfax, Virginia);  Milton N. Kabler (Alexandria, Virginia)
ABSTRACT A method for fabricating a transducer suitable for a fluidic drive for a miniature acoustic-fluidic pump or mixer that includes an acoustic transducer attached to an exterior or interior of a fluidic circuit or reservoir. The transducer converts radio frequency electrical energy into an ultrasonic acoustic wave in a fluid that in turn generates directed fluid motion through the effect of acoustic streaming. The method includes depositing a piezo-electric thin-film onto a platinum coated silicon wafer or substrate with capping electrodes, defining each separate transducer; and dicing said piezoelectric tin-film to provide individual transducers.
FILED Monday, January 06, 2003
APPL NO 10/339257
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/25.350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07104056 Taya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Minoru Taya (Mercer Island, Washington);  Taishi Wada (Kanagawa, Japan);  Masahiro Kusaka (Hyogo, Japan);  Hsiu-hung Chen (Seattle, Washington)
ABSTRACT The present invention employs an optimized cross-sectional shape for a ferromagnetic shape memory alloy (FSMA) composite that is used in a spring-type actuator, an improved hybrid magnetic trigger for use in FSMA based actuators, an a FSMA composite based spring type actuator, an a FSMA based spring type actuator including a stack of triggering units and FSMA springs, a FSMA composite based torque actuator. The invention also includes a model that can be employed to evaluate different materials being considered as components a FSMA for a FSMA composite used in either a FSMA based torque actuator or a FSMA spring actuator.
FILED Friday, February 27, 2004
APPL NO 10/790634
ART UNIT 3748 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Power plants
060/527
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07104140 Zou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Wilcoxon Research, Inc. (Gaithersburg, Maryland)
INVENTOR(S) Lichun Zou (Vienna, Virginia);  Ken Kan Deng (Potomac, Maryland)
ABSTRACT A piezoelectric flexural sensing structure having increased sensitivity and decreased noise, without sacrifice of the sensor bandwidth. The structure is made up of a proof mass, a beam with a base and optionally having castellated bonding surfaces and two <011> poled bonding mode PMN-PT crystal plates mounted on the beam.
FILED Wednesday, December 15, 2004
APPL NO 11/011198
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/777
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07104505 Tchoryk et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Michigan Aerospace Corporation (Ann Arbor, Michigan)
INVENTOR(S) Pete Tchoryk (Ann Arbor, Michigan);  Jane Pavlich (Ann Arbor, Michigan);  Greg Wassick (Petersburg, Michigan);  Anthony B. Hays (Howell, Michigan);  Greg Ritter (Hamburg, Michigan)
ABSTRACT This invention solves problems associated with prior-art soft-dock mechanisms by placing all active components of a soft-dock system on the chaser side of the mechanism, leaving the target side of the mechanism completely passive (i.e., requiring no power expenditure or self-actuated moving parts to operate). In particular, the active components are supported on the end of a flexible cable attached to the probe, or chaser, side of the device. These components act as a sort of spring-loaded “trap.” Once the end of the probe passes into a receptacle on the target side, the mechanism is triggered, engaging it in such a way that it can no longer be pulled out of the receptacle until it is reset. The soft-docking cable may be replaced with a rigid, semi-rigid or jointed post that is used to bring a capture mechanism into engagement with its corresponding receptacle or receiving structure. The magnetic end effector may also be implemented as an electro-magnet, which requires power to maintain the holding force, or a permanent magnet, which captures a target without power. The main target cone may be either a metallic cone: or a non-metallic cone constructed of fabric, plastic, or other flexible material.
FILED Wednesday, April 23, 2003
APPL NO 10/421492
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/161
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07104515 Harless et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Harris Corporation (Melbourne, Florida)
INVENTOR(S) Richard I. Harless (Palm Bay, Florida);  Michael Hoffman (Palm Bay, Florida);  Dennis Calhoun (Palm Bay, Florida);  Robert T. Fandrich, Jr. (Palm Bay, Florida);  Andrew J. Vajanyi (Palm Bay, Florida);  Therese Boyle (Palm Bay, Florida);  David S. Albert (Palm Bay, Florida)
ABSTRACT A vibration isolation system (100) for a payload (102). The vibration isolation system provides a level of vibration isolation for all vibration translational and rotational components, while minimizing the moment of the payload mass relative to the isolation system. The system includes a base (104) and a plurality of vibration isolators (114). Each vibration isolator includes a semi-rigid first support member (202) having first portion (204) positioned below the base and an opposing second portion (206) positioned above the base, and a second support member (208) having a first portion (210) fixed to the base and an opposing second portion (212) extending above the base. An elastomeric coupling (228) couples the first support member to the second support member at a height that is approximately equal to a height of a center of gravity (302) of a combined mass of the base and the payload above the base.
FILED Friday, November 12, 2004
APPL NO 10/987061
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Supports
248/562
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105094 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) T. Richard Lee (Hacienda Heights, California);  Ye Yi (Salt Lake City, Utah)
ABSTRACT A method which uses a process reactor having three separate reaction stages to remove high concentrations of heavy metals from acidic wastewater and chemical solutions. During each of three stages the pH level of the wastewater is increased and sludge and flocculate organic and metal hydrocyl matters are removed from the wastewater to provide clean water which is discharged in to a sewer system.
FILED Thursday, October 06, 2005
APPL NO 11/250706
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/703
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105358 Majumdar et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Berkeley, California)
INVENTOR(S) Arunaya Majumdar (Orinda, California);  Thomas Michael Perazzo (Simi Valley, California);  Minyao Mao (Albany, California);  Ohmyoung Kwon (Berkeley, California);  Yang Zhao (Berkeley, California);  Guanghua Wu (Albany, California)
ABSTRACT An apparatus to measure micro-forces includes a cantilever palette with a set of cantilever array blocks. Each cantilever array block includes a set of cantilevers, with each cantilever including a set of cantilever fingers surrounded by a frame with frame fingers. The cantilever fingers and the frame fingers form a diffraction grating. Each cantilever array block is configured to be responsive to a predetermined micro-force, such that cantilevers of the cantilever array block deflect in the presence of the predetermined micro-force, which causes the diffraction grating to diffract light and thereby provide a visual indication of the presence of the predetermined micro-force.
FILED Wednesday, February 13, 2002
APPL NO 10/076838
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/518
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105542 Brueggemeier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S) Robert W. Brueggemeier (Dublin, Ohio);  Young-Woo Kim (Columbus, Ohio)
ABSTRACT The present invention provides 2-heterosubstituted 3-aryl-4H-benzopyran-4-one compounds for the treatment of cancers, namely breast cancer. This invention further provides a method of synthesis of 2-(alkylthio)isoflavones that can be carried out at ambient conditions. This invention further provides a method of synthesis of the 2-heterosubstituted 3-aryl-4H-benzopyran-4-one from a 2-(alkylthio)isoflavone. The invention further provides methods of using the 2-heterosubstituted 3-aryl-4H-benzopyran-4-one compounds for the treatment of breast cancer in mammals.
FILED Monday, August 04, 2003
APPL NO 10/634463
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105617 Weck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Marcus Weck (Atlanta, Georgia);  Amy Meyers (Atlanta, Georgia)
ABSTRACT This invention relates to the synthesis of Mqn-containing monomeric compounds, comprising a polymerizable moiety, an Mqn-moiety, and an optional chemical spacer therebetween, wherein q, in each instance, comprises an 8-hydroxyquinoline residue, M is a metal such as Mg, Zn, Al, Ga, or In, and n is 2 or 3 as the valence of the metal requires. For example, the polymerization of Znq2- or Alq3-containing monomers, in the presence or absence of a co-monomer, provided a Znq2- or Alq3-containing polymer, which retained the optical properties of Znq2 or Alq3 in solution, respectively. The Mqn-containing polymers may be used in, among other things, the fabrication of light-emitting diodes (LEDs).
FILED Friday, February 06, 2004
APPL NO 10/773980
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
526/171
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105799 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior Universtiy (Palo Alto, California)
INVENTOR(S) Ray Chen (Stanford, California);  David A. B. Miller (Stanford, California)
ABSTRACT An electronically tuned, wavelength-dependent optical detector is provided. The electronically tuned, wavelength-dependent optical detector is a modified metal-semiconductor-metal photodetector including a comb-like metal electrode at a common voltage and metal electrodes each supplied with a control voltage by a voltage means. The wavelength to be detected in an optical input illuminating the detector is selected based on the set of control voltages applied to the metal electrodes. In another embodiment of the invention, the wavelength to be detected with the electronically tuned, wavelength-dependent optical detector is also selected using a standing wave generator, such as an interferometer, to produce a spatially varying light intensity on the surface of the electronically tuned, wavelength-dependent optical detector. Electronic wavelength demultiplexing is also provided. Design flexibility can be obtained by providing two or more optical patterns at a detector surface, each pattern having a different wavelength dependence.
FILED Wednesday, August 11, 2004
APPL NO 10/917272
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/214.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105820 Federici et al.
FUNDED BY
Department of Defense (DOD)
Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC)
Technical Support Working Group (TSWG)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Education (ED)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) John F. Federici (Westfield, New Jersey);  Dale E. Gary (Berkeley Heights, New Jersey)
ABSTRACT Near field imaging using a THz imaging system is realized by utilizing an interferometric imaging detector array that includes detector elements disposed on a surface curved, physically or artificially, to match substantially the curvature of the wave front for received THz signals. Generally, the near field is an environment wherein the distance to an object of interest is on the order of 10–100 times larger than the physical size of the THz imaging array. Typical distances from the object or target to the imaging array is anticipated to be in the 0.5 m–50 m range. Curvature of the detector array corrects a distortion problem in prior THz imaging systems that utilized planar interferometric imaging arrays based on a planar wave front assumption for received THz signals.
FILED Tuesday, January 18, 2005
APPL NO 11/037507
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/339.20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105831 Kronenberg, legal representative et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Eva Maria Kronenberg, legal representative (Skillman, New Jersey);  George J. Brucker (Shrewsbury, New Jersey)
ABSTRACT An ionized alpha particle detector to directly measure alpha activity in ambient air that counts alpha pulses instead of measuring radon concentration is provided by an open-air ionization chamber, a means for collecting ions, a voltage source, a charging means and a means for recording alpha pulses. The ionized alpha particle detector allows the user to directly measure the alpha particle activity in ambient air and consequently, better assess the radiological public health risk from alpha particles emitted by inhaled air. The ionized alpha particle detector advantageously overcomes the difficulties in measuring alpha particles caused by oxygen ions that quickly attract electrons and form negative ions that compensate positive charged particles and prevent the formation of alpha particle pulses. The open-air ionization chamber of the ionized alpha particle detector prevents and overcomes the problems, shortcomings, drawbacks and limitations caused by oxygen ions by generating alpha pulses that can be readily detected. The present invention also provides an ionized alpha particle detector system and a method for detecting ionized alpha particles to directly measure alpha activity in ambient air.
FILED Wednesday, April 09, 2003
APPL NO 10/410449
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/382
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105834 Angal et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Innovative Productivity, Inc. (Loiusville, Kentucky)
INVENTOR(S) Jayant R. Angal (Louisville, Kentucky);  Paul D. Gossen (Louisville, Kentucky);  Stephen W. Brewer (New Albany, Indiana)
ABSTRACT A system for detecting voids or imperfections such as holidays in a coating having fluorescent material therein comprises a camera having a digital image output for inspecting the coating wherein said camera's digital image output may include only the image produced by light in a color spectrum corresponding to a portion of the spectrum of light produced by fluorescent emission of the coating, thereby revealing the presence of any imperfections. Furthermore, an ultraviolet light source is provided to illuminate the coating and excite fluorescent emission therein. In one embodiment, the system is capable of distinguishing between an imperfection and the complete absence of a substrate surface. The system is also capable of revealing coating defects or imperfections in irregular surfaces. A microcontroller is also provided, having an associated memory, an input for accepting the digital image output from the camera, and an output representative of an analyzed digital image wherein said analyzed digital image includes visible indicia of any voids or imperfections detected in the coating.
FILED Friday, January 21, 2005
APPL NO 11/040143
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/458.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105948 Steimer
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) ABB Schweiz AG (Baden, Switzerland)
INVENTOR(S) Peter Steimer (Unterehrendingen, Switzerland)
ABSTRACT A method and apparatus for the voltage maintenance of an electrical AC voltage supply network comprising a partial converter system, which has a first branch pair and a second branch pair connected in parallel therewith and an electrical energy store connected in parallel with the branch pairs. Each branch pair is formed from two series-connected driveable power semiconductor switches, each with a diode reverse-connected in parallel, and the junction point of the power semiconductor switches of the first branch pair forming a first terminal and the junction point of the power semiconductor switches of the second branch pair forming a second terminal. The partial converter system has a third branch pair connected in parallel with the first and second branch pairs. The junction point of the power semiconductor switches of the third branch pair forms a third terminal.
FILED Tuesday, September 10, 2002
APPL NO 10/237874
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electrical transmission or interconnection systems
37/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106004 Greenwood
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Andrew D. Greenwood (Albuquerque, New Mexico)
ABSTRACT An axial extractor to efficiently extract microwave power from any magnetron. The axial extractor is both more compact and offers improved overall performance compared to the prior art. The axial extractor allows for suppression of the parasitic magnetron 0 mode, lowers field stress inside the device, and lowers the frequency of operation. These improvements also make it possible for the magnetron itself to be made smaller without a loss of power output.
FILED Monday, December 20, 2004
APPL NO 11/015316
ART UNIT 2821 — Electrical Circuits and Systems
CURRENT CPC
Electric lamp and discharge devices: Systems
315/39.510
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106055 Goldfine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Jentek Sensors, Inc. (Waltham, Massachusetts)
INVENTOR(S) Neil J. Goldfine (Newton, Massachusetts);  Vladimir A. Zilberstein (Chestnut Hill, Massachusetts);  David C. Grundy (Reading, Massachusetts);  Volker Weiss (Syracuse, New York);  Andrew P. Washabaugh (Chula Vista, California)
ABSTRACT Fabrication of samples having material conditions or damage representative of actual components inspected by nondestructive testing involves sensors placed near or mounted on the material surface, such as flexible eddy current sensors or sensor arrays, to monitor the material condition while the sample is being processed. These sample typically have real cracks in or around holes, on curved surfaces, in and under coatings, and on shot peened or otherwise preconditioned surfaces. Processing, such as mechanical or thermal loading to introduce fatigue damage, is stopped once the material condition reaches a predetermined level.
FILED Monday, November 15, 2004
APPL NO 10/989115
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/238
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US 07106079 Drost et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) SUN Microsystems, Inc. (Santa Clara, California)
INVENTOR(S) Robert J. Drost (Mountain View, California);  Ronald Ho (Mountain View, California);  Robert J. Proebsting (Sonora, California)
ABSTRACT A system that improves communications between capacitively coupled integrated circuit chips. The system operates by situating an interposer over capacitive communication pads on a first integrated circuit chip, wherein the interposer is made up of material that is anisotropic with respect to transmitting capacitive signals. A second integrated circuit chip is situated so that communication pads on the second integrated circuit chip are aligned to capacitively couple signals between the integrated circuit chips through the interposer. The increased dielectric permittivity caused by the interposer can improve capacitive coupling between opposing communication pads on the integrated circuit chips. The interposer can also reduce cross talk between communication pads on the first integrated circuit chip and pads adjacent to the opposing communication pads on the second integrated circuit chip.
FILED Friday, October 22, 2004
APPL NO 10/973114
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Electricity: Measuring and testing
324/754
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US 07106250 Blunt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Shannon D. Blunt (Alexandria, Virginia);  Karl R. Gerlach (Chesapeake Beach, Maryland)
ABSTRACT A method for processing a received, modulated pulse (i.e. waveform) that requires predictive deconvolution to resolve a scatterer from noise and other scatterers includes receiving a return signal; obtaining L+(2M−1)(N−1) samples y of the return signal, where y(l)={tilde over (x)}T(l) s+v(l); applying RMMSE estimation to each successive N samples to obtain initial impulse response estimates [{circumflex over (x)}1{−(M−1)(N−1)}, . . . , {circumflex over (x)}1{−1}, {circumflex over (x)}1 {0}, . . . , {circumflex over (x)}1{L−1}, . . . , {circumflex over (x)}1{L}, {circumflex over (x)}1{−1 +(M−1)(N−1)}]; computing power estimates {circumflex over (ρ)}1(l)=|{circumflex over (x)}1(l)|α for l=−(M−1)(N−1), . . . , L−1+(M−1)(N−1) and 0<α≦2; computing MMSE filters according to w(l)=ρ(l) (C(l)+R)−1s, where ρ(l)=E[|x(l)|α] is the power of x(l), for 0<α≦2, and R=E[v(l) vH(l)] is the noise covariance matrix; applying the MMSE filters to y to obtain [{circumflex over (x)}2{−(M−2)(N−1)}, . . . , {circumflex over (x)}2{−1}, {circumflex over (x)}2{0}, . . . , {circumflex over (x)}2{L−1}, {circumflex over (x)}2{L}, . . . , {circumflex over (x)}2{L−1+(M−2)(N−1)}]; and repeating (d)–(f) for subsequent reiterative stages until a desired length-L range window is reached, thereby resolving the scatterer from noise and other scatterers. The RMMSE predictive deconvolution approach provides high-fidelity impulse response estimation. The RMMSE estimator can reiteratively estimate the MMSE filter for each specific impulse response coefficient by mitigating the interference from neighboring coefficients that is a result of the temporal (i.e. spatial) extent of the transmitted waveform. The result is a robust estimator that adaptively eliminates the spatial ambiguities that occur when a fixed receiver filter is used.
FILED Thursday, September 23, 2004
APPL NO 10/947784
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/195
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US 07106269 Tonn
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David A. Tonn (Charlestown, Rhode Island)
ABSTRACT A relative phase shift is induced in the signals of a pair of identical orthogonal antennas such that when the signals are combined the signals are 90 degrees out of phase. This is done in order to eliminate the null along the axis between the two dipole moments of the antennas such that the system has equally good reception from all azimuth angles over a broad range of frequencies. The phase shift is accomplished with the use of single pole operational amplifier circuits whose pole frequencies are adjusted by means of a potentiometer prior to implementation of the antenna system.
FILED Friday, February 18, 2005
APPL NO 11/076107
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/820
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US 07106327 Narasimhan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Srinivasa Narasimhan (New York, New York);  Shree Nayar (New York, New York)
ABSTRACT The present invention provides systems and methods for modeling the impact of a medium on the appearances of encompassed light sources using a Legendre polynomial series solution to a Radiative Transfer Equation for Spherical Media (RTE-SM) called an Atmospheric Point Spread Function (APSF). Using this APSF, it is possible to determine characteristics of the medium causing the multiple scattering of the light from the encompassed light source. For example, by observing a street light in bad weather at night, using the APSF, it is possible to determine whether the bad weather is haze, mist, fog, or rain. Similarly, the APSF may be used to estimate the size of particles in a liquid. It is also possible using the APSF to remove and/or add an effect of the medium on a light source captured in an image.
FILED Wednesday, November 26, 2003
APPL NO 10/723084
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/426
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US 07106430 Falbel
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Gerald Falbel (Stamford, Connecticut)
ABSTRACT An airborne search and rescue scanner is provided to locate a missing person wearing a reflector for reflecting laser energy emitted from a scanner in a high speed aircraft. The scanner and reflector combination enable scanning of a large search area in a relatively short time period. The system is designed to prevent false readings, as for example, sun glint reflected by the reflector, or false alarms resulting from reflections from the terrain being searched and not the reflector worn by the missing person. In an alternative embodiment of the invention, the active laser scanning system is replaced by a passive infrared scanner by replacing the laser scanner with an infrared detector. In this embodiment, it is not necessary for the missing person to wear a reflector.
FILED Thursday, April 08, 2004
APPL NO 10/820300
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/140
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US 07106436 Gord et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) James R. Gord (Wright Patterson AFB, Ohio);  Sukesh Roy (Dayton, Ohio);  Robert P. Lucht (West Lafayette, Indiana);  Michael S. Brown (Dayton, Ohio);  Gregory J. Fiechtner (Livermore, California)
ABSTRACT A triple-pump coherent anti-Stokes Raman scattering (CARS) system for simultaneous measurements of temperature and species concentrations with high spatial and temporal resolution is described, wherein four laser beams generate CARS signals near two distinct wavelengths exhibiting an N2 CARS signal along with the CARS signal from another target molecule, each pair of CARS signals generated over a relatively narrow wavelength region and captured with fixed-wavelength detection. Temperature and relative concentrations of the target species with respect to N2 are extracted by fitting the measured CARS spectrum in each wavelength region.
FILED Wednesday, December 03, 2003
APPL NO 10/726360
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
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US 07106447 Hays
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Aeronautical Systems Center (ASC)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Advanced Simulation and Computing Program (ASC)
APPLICANT(S)
ASSIGNEE(S) Michigan Aerospace Corporation (Ann Arbor, Michigan)
INVENTOR(S) Paul B. Hays (Ann Arbor, Michigan)
ABSTRACT A first beam of light from a laser is split by a beam splitter into a reference beam and at least one second beam of light, the latter of which is directed from an optical head into an atmosphere. Light from the at least one second beam of light scattered by molecules or aerosols in the atmosphere is collected by a corresponding at least one telescope of the optical head as at least one light signal. The at least one light signal and the reference beam are simultaneously processed by different portions of a Fabry-Pérot interferometer, and resulting fringe patterns are imaged onto a detector and processed by a data processor to determine at least one associated air data product.
FILED Friday, February 14, 2003
APPL NO 10/366910
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
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US 07106658 Cray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin A. Cray (West Kingston, Rhode Island);  Harold T. Vincent, II (North Kingstown, Rhode Island)
ABSTRACT An apparatus for determining a position includes a source which transmits a signal having a source position and a transmission time coded therein. A sensor having a directional beam pattern is positioned at the location of interest. A signal processor steers the directional beam pattern of the sensor in order to determine the direction to the signal source. A sensor processor uses a clock to find a receipt time of the signal. The transmission time and source position is decoded from the signal. The position of interest is calculated from the receipt time, transmission time, direction, and source position. A method is also provided.
FILED Thursday, January 27, 2005
APPL NO 11/042004
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/119
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US 07106784 Eltawil et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Sasken Communication Technologies Limited (Bangalore, India)
INVENTOR(S) Ahmed Eltawil (Los Angeles, California);  Babak Daneshrad (Encino, California)
ABSTRACT A universal rake receiver architecture includes modular independent processing units that can be flexibly programmed to support different modes of operation. The processing units are capable of performing the basic correlation calculations of DS-CDMA and each unit has an internal local memory and controller that controls its mode of operation. Each unit performs the required synchronization and demodulation operations for a multipath of a signal in the digital domain using all-digital frequency and timing correction techniques. Frequency feedback need not be supplied to the analog section of the receiver. Interpolation most preferably is used to find the optimum sampling position of each incoming chip. This independence allows the receiver to be used with one to several antennas without design modifications.
FILED Friday, January 25, 2002
APPL NO 10/057430
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/148
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US 07106917 Painter et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Xponent Photonics Inc (Monrovia, California)
INVENTOR(S) Oskar J. Painter (Pasadena, California);  Peter C. Sercel (Pasadena, California);  Kerry J. Vahala (San Gabriel, California);  David W. Vernooy (Sierra Madre, California);  Guido Hunziker (Altadena, California)
ABSTRACT A resonant optical modulator comprises a transmission fiber-optic waveguide, a circumferential-mode optical resonator transverse-coupled thereto, a modulator optical component transverse-coupled to the circumferential-mode resonator, and a modulator control component. A control signal applied to the modulator optical component through the modulator control component alters the round-trip optical loss of the circumferential-mode resonator, thereby altering the transmission of a resonant optical signal through the transmission fiber-optic waveguide. The modulator optical element may comprise an open waveguide or a closed waveguide (i.e., resonator). The resonator round-trip optical loss may be altered by altering the optical absorption/scattering of the modulator optical component, by altering the amount of optical power transfer between the resonator and the modulator optical component, or by altering an optical resonance frequency of a resonant modulator optical component.
FILED Friday, December 21, 2001
APPL NO 10/037146
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/2
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US 07106971 Davis
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Christopher C. Davis (Bowie, Maryland)
ABSTRACT A system and method for optical wireless communication with fading resistance. A delayed diversity approach reduces fading significantly. Data is sent in a set of light signals (also called diverse light signals) which each have a different polarization and/or a different wavelength. The diverse light signals are also temporally different in that they are transmitted in a delayed fashion with respect to one another. In this way, each light signal is carried over a different, uncorrelated “channel” through the atmosphere. At a receiver, original data in each received light signals is temporally adjusted and combined into a single output data signal. The accuracy of each bit in the output data signal is then due to the reception of the combined diverse light signals. In this way, even if fading occurs in one channel (effecting one diverse light signal), a combined output data signal can still be generated at relatively high accuracy from the original data carried in one or more of the other diverse light signals.
FILED Friday, June 30, 2000
APPL NO 10/018957
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/125
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US 07107118 Orozco et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Applied Thermal Sciences, Inc. (Sanford, Maine)
INVENTOR(S) Nelson J. Orozco (Wells, Maine);  Paul A. Blomquist (Sanford, Maine);  Kendrick H. Light (Gorham, Maine);  Robert B. Rudy (Limerick, Maine);  Steven R. Webber (Springvale, Maine)
ABSTRACT A fully integrated automated laser weld process control system (LWPCS) and method of controlling the fabrication of structural parts, particularly for shipbuilding and other industries. The LWPCS defines joint and weld quality attributes as process control variables and integrates these weld quality variables, along with the more traditional process parameters such as laser power, wire feed, GMAW voltage and active seam tracking, into a closed-loop monitoring and control system. The LWPCS includes a central processor and a plurality of subsystems that control laser beam positioning, vision-based monitoring and image processing, active weld-quality monitoring and inspection, adaptive beam delivery, and seam tracking. Cross-communication between subsystems is managed by the central processor. In addition to process control, the system extracts weld quality attributes during the weld process and provides immediate documentation of the weld quality.
FILED Thursday, June 03, 2004
APPL NO 10/860687
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Generic control systems or specific applications
7/166
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US 07107144 Capozzi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S) Spectra Research, Inc. (Dayton, Ohio)
INVENTOR(S) Jerry V. Capozzi (Bellbrook, Ohio);  Michael R. Johnson (Beavercreek, Ohio);  Gordon R. Little (Kettering, Ohio);  Paul D. Zidek (Dayton, Ohio)
ABSTRACT A traffic monitoring system including a non-intrusive lane monitor is provided. The lane monitor comprises one or more laser channels, a user interface, and a programmable controller in communication with the laser channels and the user interface. In accordance with one embodiment of the present invention, a pair of laser channels are provided. The first laser axis is substantially parallel to the second laser axis and the first and second laser axes lie substantially in a common horizontal plane. The programmable controller is configured to generate reflected laser pulse count corresponding to reflection of a pulsed laser signal from a target positioned along one of the laser axes and identify the reflected signal as a valid or invalid target by comparing the pulse count to a predetermined valid target count.
FILED Thursday, February 26, 2004
APPL NO 10/787850
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/117
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US 07107430 Grossman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jeffrey P. Grossman (Cambridge, Massachusetts);  Thomas F. Knight, Jr. (Belmont, Massachusetts);  Jeremy H. Brown (Somerville, Massachusetts);  Andrew W Huang (Cambridge, Massachusetts)
ABSTRACT Short-quasi-unique-identifiers (SQUIDs) are generated and assigned to the data objects stored in memory. Pointers to a particular data object contain the data object's assigned SQUID. If a data object is moved to a second allocated memory segment, a new pointer to the second allocated memory segment is placed at the original memory segment, so that any pointers to the original memory segment now point to the new pointer. The distribution of SQUIDs is uniform. SQUIDs can be generated by counting, generated randomly, generating through some hashing mechanism, or other means. In comparing two different pointers, it is determined that the two pointers do not reference the same data object if the SQUIDs are different. On the other hand, if the SQUIDs are identical and the address fields of the two pointers are identical, then the two pointers reference the same data object. In addition, a pointer is associated with a migration indicator field which indicates the number of migrations of the referenced data object prior to the pointer being created. The comparator determines that two pointers do not reference the same data object if their associated migration indicators indicate identical numbers of migrations and their corresponding addresses are different.
FILED Wednesday, November 14, 2001
APPL NO 09/990798
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/202
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National Science Foundation (NSF) 

US 07104139 Gao et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Robert X. Gao (Amherst, Massachusetts);  Szabolcs Sovenyi (Ann Arbor, Michigan)
ABSTRACT System and method for measuring static load by using a piezoelectric load sensor with a feedback technique to compensate for the signal loss due to charge leakage, and therefore ensures measurement accuracy. The system is integrated with other structure, objects and devices to measure static loads applied to a mechanical shaft, in an on-line, in-process, quasi real-time fashion. The system can be used to measure static load and thus oversee an entire machine system or a manufacturing process.
FILED Thursday, June 10, 2004
APPL NO 10/865742
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/777
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US 07104659 Grier et al.
FUNDED BY
Department of Education (ED)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) University of Chicago (Chicago, Illinois)
INVENTOR(S) David G. Grier (New York, New York);  Eric R. Dufresne (Arlington, Virginia);  Jennifer E. Curtis (Chicago, Illinois);  Brian A. Koss (Chicago, Illinois)
ABSTRACT A method and apparatus for control of optical trap arrays and formation of particle arrays using light that is in the visible portion of the spectrum. The method and apparatus provides a laser and a time variable diffractive optical element to allow dynamic control of optical trap arrays and consequent control of particle arrays and also the ability to manipulate singular objects using a plurality of optical traps. By avoiding wavelengths associated with strong absorption in the underlying material, creating optical traps with a continuous-wave laser, optimizing the efficiency of individual traps, and trapping extended samples at multiple points, the rate of deleterious nonlinear optical processes can be minimized.
FILED Friday, December 10, 2004
APPL NO 11/010004
ART UNIT 2881 — Optics
CURRENT CPC
Optical: Systems and elements
359/614
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US 07105051 Peng et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Xiaogang Peng (Fayetteville, Arkansas);  Weiyong Yu (Fayetteville, Arkansas);  David Battaglia (Fayetteville, Arkansas)
ABSTRACT The present invention provides substantially monodisperse colloidal nanocrystals and new preparative methods for the synthesis of substantially monodisperse colloidal nanocrystals. These synthetic methods afford the ability to tune nanocrystal size and size distribution. By using non-coordinating solvents in the synthetic process, these procedures constitute easier, less expensive, safer, and more environmentally “green” methods than those currently in use. This invention is generally applicable to any II–VI or III–V semiconductor material, and may be useful in generating metal-nonmetal compounds involving transition metals as well.
FILED Tuesday, July 30, 2002
APPL NO 10/209329
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/68
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US 07105118 Narayan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Jagdish Narayan (Raleigh, North Carolina);  Ashutosh Tiwari (Raleigh, North Carolina)
ABSTRACT Nanostructures and methods of making nanostructures having self-assembled nanodot arrays wherein nanodots are self-assembled in a matrix material due to the free energies of the nanodot material and/or differences in the Gibb's free energy of the nanodot materials and matrix materials.
FILED Wednesday, November 26, 2003
APPL NO 10/723842
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/210.600
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US 07105310 Gray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Harry B. Gray (Pasadena, California);  Brian R. Crane (Ithaca, New York);  Jay R. Winkler (Pasadena, California);  Ivan Julian Dmochowski (Philadelphia, Pennsylvania);  Jonathan J. Wilker (LaFayette, Indiana);  Alexander Robert Dunn (Colorado Springs, Colorado)
ABSTRACT Methods and compositions for detecting and characterizing target biomolecules using sensitizer-linked substrate molecules are disclosed. High throughput screening assays and therapeutic applications of the inventions are also included
FILED Wednesday, July 19, 2000
APPL NO 10/031532
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.400
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US 07105329 Zeikus et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) J. Gregory Zeikus (Okemos, Michigan);  Maris Laivenieks (East Lansing, Michigan);  Claire Vieille (Lansing, Michigan);  Pil Kim (Seoul, South Korea)
ABSTRACT An Actinobacillus succinogenes plasmid vector which provides a means to overexpress proteins in A. succinogenes. The plasmid can be transformed efficiently by electroporation, and replicates in a stable manner in A. succinogenes. The plasmid comprises at least one marker gene, operably linked to a first promoter functional in Actinobacillus succinogenes, an origin of replication functional in Actinobacillus succinogenes, a second promoter isolated from Actinobacillus succinogenes, and a cloning site downstream from the second promoter. Plasmids pLGZ901, pLGZ920, pLGZ921, and pLGZ922 are disclosed. The pckA gene polypeptide sequence and nucleic acid sequence of Actinobacillus succinogenes, including the promoter and ribosome binding site, is disclosed. Furthermore, a method for producing a recombinant Actinobacillus succinogenes is described, including a method of transformation. Additionally, a recombinant Actinobacillus succinogenes is disclosed and a method for producing succinate utilizing this recombinant Actinobacillus succinogenes is described.
FILED Tuesday, January 25, 2005
APPL NO 11/042925
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/194
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US 07105358 Majumdar et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Berkeley, California)
INVENTOR(S) Arunaya Majumdar (Orinda, California);  Thomas Michael Perazzo (Simi Valley, California);  Minyao Mao (Albany, California);  Ohmyoung Kwon (Berkeley, California);  Yang Zhao (Berkeley, California);  Guanghua Wu (Albany, California)
ABSTRACT An apparatus to measure micro-forces includes a cantilever palette with a set of cantilever array blocks. Each cantilever array block includes a set of cantilevers, with each cantilever including a set of cantilever fingers surrounded by a frame with frame fingers. The cantilever fingers and the frame fingers form a diffraction grating. Each cantilever array block is configured to be responsive to a predetermined micro-force, such that cantilevers of the cantilever array block deflect in the presence of the predetermined micro-force, which causes the diffraction grating to diffract light and thereby provide a visual indication of the presence of the predetermined micro-force.
FILED Wednesday, February 13, 2002
APPL NO 10/076838
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/518
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105580 Nair et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Prabha D. Nair (Trivandrum, India);  Buddy D. Ratner (Seattle, Washington);  Viola Vogel (Seattle, Washington);  Robert M. Nerem (Atlanta, Georgia)
ABSTRACT In one aspect the present invention provides biodegradable, porous structures that each include a structural framework, wherein the structural framework includes: (a) a solidified mixture of polymer molecules and amino acid molecules, wherein at least some of the amino acid molecules are linked to other amino acid molecules within the framework; and (b) a multiplicity of interconnected spaces defined by the structural framework. In some embodiments, the porous structures of the invention are adapted to physically support the growth of living cells in vitro or in vivo, and can be used to grow living tissue and/or living organs. The present invention also provide methods for making the biodegradable, porous structures of the invention.
FILED Thursday, December 05, 2002
APPL NO 10/314453
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Colloid systems and wetting agents; subcombinations thereof; processes of
516/98
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105617 Weck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Marcus Weck (Atlanta, Georgia);  Amy Meyers (Atlanta, Georgia)
ABSTRACT This invention relates to the synthesis of Mqn-containing monomeric compounds, comprising a polymerizable moiety, an Mqn-moiety, and an optional chemical spacer therebetween, wherein q, in each instance, comprises an 8-hydroxyquinoline residue, M is a metal such as Mg, Zn, Al, Ga, or In, and n is 2 or 3 as the valence of the metal requires. For example, the polymerization of Znq2- or Alq3-containing monomers, in the presence or absence of a co-monomer, provided a Znq2- or Alq3-containing polymer, which retained the optical properties of Znq2 or Alq3 in solution, respectively. The Mqn-containing polymers may be used in, among other things, the fabrication of light-emitting diodes (LEDs).
FILED Friday, February 06, 2004
APPL NO 10/773980
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
526/171
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US 07105680 O'Halloran et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Thomas V. O'Halloran (Wilmette, Illinois);  Masayasu Taki (Evanston, Illinois)
ABSTRACT Benzoxazole fluorescent sensor compounds and related ratiometric imaging methods for zinc metal ion.
FILED Thursday, July 08, 2004
APPL NO 10/887465
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/271.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105810 Kameoka et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Jun Kameoka (Ithaca, New York);  Harold G. Craighead (Ithaca, New York)
ABSTRACT An electrospray ionization device incorporates a shaped thin film with a microfluidic channel. The device may be interfaced to a time-of-flight mass spectrometer (TFOMS). In one embodiment, the shaped thin film has a polygonal-shaped or triangle-shaped thin polymer tip formed by lithography and etching. The microfluidic channel is approximately 20 micrometer wide and 10 micrometers deep, and embossed in a substrate using a silicon master. The shaped thin film is aligned with the channel and bonded between the channel substrate and a flat plate to create a microfluidic channel with a wicking tip protruding from the end of the channel. Application of a high voltage at one end of the channel creates an electrospray from the tip, which is provided to the TFOMS.
FILED Friday, March 21, 2003
APPL NO 10/394757
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/288
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US 07106327 Narasimhan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Srinivasa Narasimhan (New York, New York);  Shree Nayar (New York, New York)
ABSTRACT The present invention provides systems and methods for modeling the impact of a medium on the appearances of encompassed light sources using a Legendre polynomial series solution to a Radiative Transfer Equation for Spherical Media (RTE-SM) called an Atmospheric Point Spread Function (APSF). Using this APSF, it is possible to determine characteristics of the medium causing the multiple scattering of the light from the encompassed light source. For example, by observing a street light in bad weather at night, using the APSF, it is possible to determine whether the bad weather is haze, mist, fog, or rain. Similarly, the APSF may be used to estimate the size of particles in a liquid. It is also possible using the APSF to remove and/or add an effect of the medium on a light source captured in an image.
FILED Wednesday, November 26, 2003
APPL NO 10/723084
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/426
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US 07106898 Bouguet et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jean-Yves Bouguet (Milpitas, California);  Pietro Perona (Altadena, California)
ABSTRACT A system and method of determining 3D information about a 3D scene using shadows that are cast on the 3D object.
FILED Wednesday, December 06, 2000
APPL NO 09/732506
ART UNIT 2623 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/154
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US 07106918 Bita et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ion Bita (Somerville, Massachusetts);  Edwin L. Thomas (Natick, Massachusetts)
ABSTRACT A structured material is disclosed with magneto-gyrotropic characteristics including at least one continuous structurally-chiral material. The structured material has an electric permittivity and a magnetic permeability at least one of which varies within the structured material along a first direction in a repetitious fashion wherein a repetition unit includes a chiral component and is at least 25 nm in length. The structured material exhibits non-reciprocal electromagnetic wave propagation velocity characteristics along a second direction that includes a non-zero component along the first direction.
FILED Friday, May 21, 2004
APPL NO 10/851587
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/6
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Department of Energy (DOE) 

US 07104131 Taylor
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Steven C. Taylor (Idaho Falls, Idaho)
ABSTRACT Ultrasonic pulser-receiver circuitry, for use with an ultrasonic transducer, the circuitry comprising a circuit board; ultrasonic pulser circuitry supported by the circuit board and configured to be coupled to an ultrasonic transducer and to cause the ultrasonic transducer to emit an ultrasonic output pulse; receiver circuitry supported by the circuit board, coupled to the pulser circuitry, including protection circuitry configured to protect against the ultrasonic pulse and including amplifier circuitry configured to amplify an echo, received back by the transducer, of the output pulse; and a connector configured to couple the ultrasonic transducer directly to the circuit board, to the pulser circuitry and receiver circuitry, wherein impedance mismatches that would result if the transducer was coupled to the circuit board via a cable can be avoided.
FILED Wednesday, March 17, 2004
APPL NO 10/803518
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/620
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07104920 Beaty et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Eaton Corporation (Cleveland, Ohio)
INVENTOR(S) Kevin D. Beaty (Kalamazoo, Michigan);  Thomas R. Bockelmann (Battle Creek, Michigan);  Zhanijang Zou (Battle Creek, Michigan);  Mark E. Hope (Marshall, Michigan);  Xiaosong Kang (Battle Creek, Michigan);  Jeffrey L. Carpenter (Kalamazoo, Michigan)
ABSTRACT A hybrid vehicle powertrain system includes a first prime mover, a first prime mover driven power transmission mechanism having a power take-off adapted to drive a vehicle accessory, and a second prime mover. The second prime mover is operable to drive the power transmission mechanism alone or in combination with the first prime mover to provide power to the power take-off through the power transmission mechanism. The invention further includes methods for operating a hybrid vehicle powertrain system.
FILED Tuesday, September 07, 2004
APPL NO 10/935496
ART UNIT 3681 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Interrelated power delivery controls, including engine control
477/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105098 Shul et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Randy J. Shul (Albuquerque, New Mexico);  Christi G. Willison (Albuquerque, New Mexico);  W. Kent Schubert (Albuquerque, New Mexico);  Ronald P. Manginell (Albuquerque, New Mexico);  Mary-Anne Mitchell (Edgewood, New Mexico);  Paul C. Galambos (Albuquerque, New Mexico)
ABSTRACT New methods for fabrication of silicon microstructures have been developed. In these methods, an etching delay layer is deposited and patterned so as to provide differential control on the depth of features being etched into a substrate material. Compensation for etching-related structural artifacts can be accomplished by proper use of such an etching delay layer.
FILED Thursday, June 06, 2002
APPL NO 10/165356
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Etching a substrate: Processes
216/41
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US 07105714 Pecharsky et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Vitalij K Pecharsky (Ames, Iowa);  Viktor P Balema (Ames, Iowa);  Jerzy W Wiench (Ames, Iowa);  Marek Pruski (Ames, Iowa)
ABSTRACT The present invention provides a method of preparing a phosphonium salt of the formula [R1R2R3P—CR4R5R6]X, comprising ball-milling a phosphine of the formula R1R2R3P with a compound of the formula XCR4R5R6; a method of preparing a phosphorus ylide of the formula R1R2R3P═CR4R5, comprising ball-milling a phosphonium salt of the formula [R1R2R3P—HCR4R5]X in the presence of a base; and a method of preparing an olefin of the formula R4R5C═CR7H or R4R5C═CR7R8, comprising ball-milling a phosphorus ylide of the formula R1R2R3P═CR4R5 with a compound of the formula R7C(O)H or R7C(O)R8. The inventive method produces phosphonium salts and phosphorus ylides by mechanical processing solid reagents under solvent-free conditions. The advantages of the present invention over conventional solution methods, include: (1) extremely high selectivity; (2) high yields; (3) low processing temperatures; (4) simple and scalable reactions using commercially available equipment; and (5) the complete elimination of solvents from the reaction.
FILED Monday, December 22, 2003
APPL NO 10/744932
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Chemistry of hydrocarbon compounds
585/503
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105832 Dai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  Oak Ridge Associated Universities (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Sheng Dai (Knoxville, Tennessee);  Hee-Jung Im (Knoxville, Tennessee);  Michelle D. Pawel (Oak Ridge, Tennessee)
ABSTRACT Applicant's present invention is a composite scintillator for neutron detection comprising a matrix material fabricated from an inorganic sol-gel precursor solution homogeneously doped with a liquid scintillating material and a neutron absorbing material. The neutron absorbing material yields at least one of an electron, a proton, a triton, an alpha particle or a fission fragment when the neutron absorbing material absorbs a neutron. The composite scintillator further comprises a liquid scintillating material in a self-assembled micelle formation homogeneously doped in the matrix material through the formation of surfactant-silica composites. The scintillating material is provided to scintillate when traversed by at least one of an electron, a proton, a triton, an alpha particle or a fission fragment. The scintillating material is configured such that the matrix material surrounds the micelle formation of the scintillating material. The composite scintillator is fabricated and applied as a thin film on substrate surfaces, a coating on optical fibers or as a glass material.
FILED Wednesday, April 07, 2004
APPL NO 10/819761
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/390.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106173 Scott et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jeff W. Scott (Pasco, Washington);  Richard M. Pratt (Richland, Washington)
ABSTRACT Tags, wireless communication systems, tag communication methods, and wireless communications methods are described. In one aspect, a tag includes a plurality of antennas configured to receive a plurality of first wireless communication signals comprising data from a reader, a plurality of rectifying circuits coupled with. respective individual ones of the antennas and configured to provide rectified signals corresponding to the first wireless communication signals, wherein the rectified signals are combined to produce a composite signal, an adaptive reference circuit configured to vary a reference signal responsive to the composite signal, a comparator coupled with the adaptive reference circuit and the rectifying circuits and configured to compare the composite signal with respect to the reference signal and to output the data responsive to the comparison, and processing circuitry configured to receive the data from the comparator and to process the data.
FILED Friday, January 03, 2003
APPL NO 10/336086
ART UNIT 2635 — Semiconductors/Memory
CURRENT CPC
Communications: Electrical
340/10.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106447 Hays
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Aeronautical Systems Center (ASC)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Advanced Simulation and Computing Program (ASC)
APPLICANT(S)
ASSIGNEE(S) Michigan Aerospace Corporation (Ann Arbor, Michigan)
INVENTOR(S) Paul B. Hays (Ann Arbor, Michigan)
ABSTRACT A first beam of light from a laser is split by a beam splitter into a reference beam and at least one second beam of light, the latter of which is directed from an optical head into an atmosphere. Light from the at least one second beam of light scattered by molecules or aerosols in the atmosphere is collected by a corresponding at least one telescope of the optical head as at least one light signal. The at least one light signal and the reference beam are simultaneously processed by different portions of a Fabry-Pérot interferometer, and resulting fringe patterns are imaged onto a detector and processed by a data processor to determine at least one associated air data product.
FILED Friday, February 14, 2003
APPL NO 10/366910
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106448 Vawter et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) G. Allen Vawter (Albuquerque, New Mexico);  Walter J. Zubrzycki (Sandia Park, New Mexico);  Junpeng Guo (Albuquerque, New Mexico);  Charles T. Sullivan (Albuquerque, New Mexico)
ABSTRACT An integrated optic gyroscope is disclosed which is based on a photonic integrated circuit (PIC) having a bidirectional laser source, a pair of optical waveguide phase modulators and a pair of waveguide photodetectors. The PIC can be connected to a passive ring resonator formed either as a coil of optical fiber or as a coiled optical waveguide. The lasing output from each end of the bidirectional laser source is phase modulated and directed around the passive ring resonator in two counterpropagating directions, with a portion of the lasing output then being detected to determine a rotation rate for the integrated optical gyroscope. The coiled optical waveguide can be formed on a silicon, glass or quartz substrate with a silicon nitride core and a silica cladding, while the PIC includes a plurality of III–V compound semiconductor layers including one or more quantum well layers which are disordered in the phase modulators and to form passive optical waveguides.
FILED Tuesday, February 17, 2004
APPL NO 10/780799
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/461
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07107015 Stepp et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Jeffrey David Stepp (Grandview, Missouri);  Dale Hensley (Grandview, Missouri)
ABSTRACT A frequency transverter (10) and method for enabling bi-frequency dual-directional transfer of digitally encoded data on an RF carrier by translating between a crowded or otherwise undesirable first frequency band, such as the 2.4 GHz ISM band, and a less-crowded or otherwise desirable second frequency band, such as the 5.0 GHz–6.0 GHz U-NII band. In a preferred embodiment, the transverter (10) connects between an existing data radio (11) and its existing antenna (30), and comprises a bandswitch (12); an input RF isolating device (14); a transmuter (16); a converter (18); a dual output local oscillator (20); an output RF isolating device (22); and an antenna (24) tuned to the second frequency band. The bandswitch (12) allows for bypassing the transverter (10), thereby facilitating its use with legacy systems. The transmuter (14) and converter (16) are adapted to convert to and from, respectively, the second frequency band.
FILED Thursday, April 21, 2005
APPL NO 11/111555
ART UNIT 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Telecommunications
455/81
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07104143 Powell
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Arthur Gregory Powell (Westminster, California)
ABSTRACT An oscillating vane actuator for active control of fluid flow over a surface includes a pivoted vane surrounded by a wedge-shaped chamber, and first and second conduits with openings adjacent the surface. The actuator also includes a rotating shaft with a connecting rod to actuate the vane in a oscillatory manner. As the vane travels in one direction, fluid is forced out from the chamber through the first conduit and opening into the fluid stream adjacent the surface, while fluid is simultaneously drawn in through the second opening and conduit into the opposite side of the chamber. Similarly, when the vane travels in the opposite direction, fluid is forced out through the second conduit and opening into the fluid stream adjacent the surface, while fluid is simultaneously drawn in through the first opening and conduit.
FILED Thursday, August 11, 2005
APPL NO 11/201387
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/861.740
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07104498 Englar et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corp. (Atlanta, Georgia)
INVENTOR(S) Robert J. Englar (Marietta, Georgia);  Dennis M. Bushnell (Hayes, Virginia)
ABSTRACT An aircraft comprising a Channel Wing having blown channel circulation control wings (CCW) for various functions. The blown channel CCW includes a channel that has a rounded or near-round trailing edge. The channel further has a trailing-edge slot that is adjacent to the rounded trailing edge of the channel. The trailing-edge slot has an inlet connected to a source of pressurized air and is capable of tangentially discharging pressurized air over the rounded trailing edge. The aircraft further has a propeller that is located in the channel and ahead of the rounded trailing edge of the channel. The propeller provides a propeller thrust exhaust stream across the channel wing to propel the aircraft through the air and to provide high lift. The pressurized air being discharged over the rounded trailing edge provides a high lift that is obtained independent of an aircraft angle of attack, thus preventing the asymmetry, separated flow, and stall experienced by the CC wing at the high angle of attack it required for high lift generation. The aircraft can further include blown outboard circulation control wings (CCW) that are synergistically connected to the blown channel CCWs. The blown outboard CCWs provide additional high lift, control thrust/drag interchange, and can provide all three aerodynamic moments when differential blowing is applied front-to-rear or left-to-right. Both the blown channel CCW and the outboard CCW also have leading-edge blowing slots to prevent flow separation or to provide aerodynamic moments for control.
FILED Monday, June 14, 2004
APPL NO 10/867114
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/12.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105067 Sankaran et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Krishnan K. Sankaran (St. Louis, Missouri);  Brian J. Sova (St. Charles, Missouri);  Henry W. Babel (Huntington Beach, California)
ABSTRACT A method to increase the toughness of the aluminum-lithium alloy C458 and similar alloys at cryogenic temperatures above their room temperature toughness is provided. Increasing the cryogenic toughness of the aluminum-lithium alloy C458 allows the use of alloy C458 for cryogenic tanks, for example for launch vehicles in the aerospace industry. A two-step aging treatment for alloy C458 is provided. A specific set of times and temperatures to age the aluminum-lithium alloy C458 to T8 temper is disclosed that results in a higher toughness at cryogenic temperatures compared to room temperature. The disclosed two-step aging treatment for alloy 458 can be easily practiced in the manufacturing process, does not involve impractical heating rates or durations, and does not degrade other material properties.
FILED Thursday, June 05, 2003
APPL NO 10/456385
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Metal treatment
148/698
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105371 Fossum et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Eric R. Fossum (LaCrescenta, California);  Sunetra Mendis (Pasadena, California);  Sabrina E. Kemeny (LaCrescenta, California)
ABSTRACT An imaging device formed as a monolithic complementary metal oxide semiconductor integrated circuit in an industry standard complementary metal oxide semiconductor process, the integrated circuit including a focal plane array of pixel cells, each one of the cells including a photogate overlying the substrate for accumulating photo-generated charge in an underlying portion of the substrate, a readout circuit including at least an output field effect transistor formed in the substrate, and a charge coupled device section formed on the substrate adjacent the photogate having a sensing node connected to the output transistor and at least one charge coupled device stage for transferring charge from the underlying portion of the substrate to the sensing node.
FILED Wednesday, November 12, 2003
APPL NO 10/712844
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/48
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106203 Edwards et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William C. Edwards (Poquoson, Virginia);  Terry L. Mack (Hampton, Virginia);  Edward A. Modlin (Yorktown, Virginia)
ABSTRACT A system and method use a wireless tether comprising a transmitter and a receiver to alert a caregiver that an object has been left unattended. A detector senses the presence of the object, usually a child, located in a position such as a safety seat. The detector is operatively coupled to the transmitter, which is located near the object. The transmitter transmits at least one wireless signal when the object is in the position. The receiver, which is remotely located from the transmitter, senses the at least one signal as long as the receiver is within a prescribed range of transmission. By performing a timing function, the receiver monitors the proximity of the caregiver, who maintains possession of the receiver, to the transmitter. The system communicates an alarm to the caregiver when the caregiver ventures outside the range of transmission without having removed the object from the position.
FILED Friday, February 20, 2004
APPL NO 10/783486
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/573.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106457 Stahl et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) H. Philip Stahl (Brownsboro, Alabama);  Chanda Bartlett Walker (Houston, Texas)
ABSTRACT An achromatic shearing phase sensor generates an image indicative of at least one measure of alignment between two segments of a segmented telescope's mirrors. An optical grating receives at least a portion of irradiance originating at the segmented telescope in the form of a collimated beam and the collimated beam into a plurality of diffraction orders. Focusing optics separate and focus the diffraction orders. Filtering optics then filter the diffraction orders to generate a resultant set of diffraction orders that are modified. Imaging optics combine portions of the resultant set of diffraction orders to generate an interference pattern that is ultimately imaged by an imager.
FILED Friday, May 21, 2004
APPL NO 10/857372
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/521
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106502 McDowell
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Mark McDowell (Cleveland, Ohio)
ABSTRACT A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to auto-focus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.
FILED Friday, February 04, 2005
APPL NO 11/053758
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/368
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106762 Jiang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S) NP Photonics, INC (Tucson, Arizona)
INVENTOR(S) Shibin Jiang (Tucson, Arizona);  Christine Spiegelberg (Tucson, Arizona);  Tao Luo (Tucson, Arizona)
ABSTRACT A compact single frequency, single-mode 2 μm fiber laser with narrow linewidth, <100 kHz and preferably <100 kHz, is formed with a low phonon energy glass doped with triply ionized rare-earth thulium and/or holmium oxide and fiber gratings formed in sections of passive silica fiber and fused thereto. Formation of the gratings in passive silica fiber both facilitates splicing to other optical components and reduces noise thus improving linewidth. An increased doping concentration of 0.5 to 15 wt. % for thulium, holmium or mixtures thereof produces adequate gain, hence output power levels for fiber lengths less than 5 cm and preferably less than 3 cm to enable single-frequency operation.
FILED Thursday, February 19, 2004
APPL NO 10/783480
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/6
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07105071 Johnson et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Ebert Composites Corporation (Chula Vista, California)
INVENTOR(S) David W. Johnson (San Diego, California);  Scott A. Garrett (San Diego, California);  James M. Hook (Alpine, California);  Stephen G. Moyers (Jamul, California)
ABSTRACT A method of inserting z-axis reinforcing fibers into a multi-layer composite laminate. Layers of material made up of z-axis fiber and y-axis fibers are automatically transported into a z-fiber deposition machine having a housing with upper and lower surfaces. Z-axis apertures are formed in the respective upper and lower surfaces. An elongated solid rod having a tapered front tip is aligned in close proximity to the aperture in the bottom surface. The rod is first rotated by a motor and then actuated upwardly completely through the thickness of the layer of x-y material by an actuator. A first hollow tube having a z-axis is axially aligned with the aperture in the top surface and a fiber bundle is threaded downwardly through a first hollow tube to a position adjacent its bottom end. The z-fiber deposition machine has structure to feed a predetermined length of the fiber bundle downwardly through the first hollow tube so that it follows the pathway in the x-y material formed by the rod which is now withdrawn downwardly through the aperture in the bottom wall. The z-axis fiber is thus deposited into the x-y material. The top end of the z-axis fiber is then severed and the x-y material is then advanced a predetermined distance to complete the cycle and is, thus, set to be repeated.
FILED Monday, November 10, 2003
APPL NO 10/705047
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/92
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105375 Wu et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Stamford, Connecticut)
INVENTOR(S) Yiliang Wu (Ontario, Canada);  Nan-Xing Hu (Ontario, Canada);  Beng S. Ong (Ontario, Canada)
ABSTRACT A method of patterning organic semiconductor layers of electronic devices utilizing reverse printing.
FILED Friday, July 30, 2004
APPL NO 10/909081
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106441 Sun et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Stamford, Connecticut)
INVENTOR(S) Decai Sun (Los Altos, California);  Joel A. Kubby (Rochester, New York);  Jingkuang Chen (Rochester, New York);  Alex T. Tran (Madison, New Jersey);  Patrick Y. Maeda (Mountain View, California)
ABSTRACT A tunable microelectromechanical (MEMS) spectrophotometer with a rotating cylindrical reflective diffraction grating is integrated with a photodetector and an optical fiber light source on a Rowland circle on a monolithic silicon substrate.
FILED Friday, September 26, 2003
APPL NO 10/672207
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/328
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07105329 Zeikus et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) J. Gregory Zeikus (Okemos, Michigan);  Maris Laivenieks (East Lansing, Michigan);  Claire Vieille (Lansing, Michigan);  Pil Kim (Seoul, South Korea)
ABSTRACT An Actinobacillus succinogenes plasmid vector which provides a means to overexpress proteins in A. succinogenes. The plasmid can be transformed efficiently by electroporation, and replicates in a stable manner in A. succinogenes. The plasmid comprises at least one marker gene, operably linked to a first promoter functional in Actinobacillus succinogenes, an origin of replication functional in Actinobacillus succinogenes, a second promoter isolated from Actinobacillus succinogenes, and a cloning site downstream from the second promoter. Plasmids pLGZ901, pLGZ920, pLGZ921, and pLGZ922 are disclosed. The pckA gene polypeptide sequence and nucleic acid sequence of Actinobacillus succinogenes, including the promoter and ribosome binding site, is disclosed. Furthermore, a method for producing a recombinant Actinobacillus succinogenes is described, including a method of transformation. Additionally, a recombinant Actinobacillus succinogenes is disclosed and a method for producing succinate utilizing this recombinant Actinobacillus succinogenes is described.
FILED Tuesday, January 25, 2005
APPL NO 11/042925
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/194
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105343 Fraser, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) University of Notre Dame du Lac (Notre Dame, Indiana)
INVENTOR(S) Malcolm J. Fraser, Jr. (Granger, Indiana);  Xu Li (Notre Dame, Indiana)
ABSTRACT The present invention provides efficient transfer of genes into host cells or embryos to transform the cells or embryos by transposition vectors using the minimal amount of nucleotide sequences in the transposon piggyBac required for gene transfer. The transformed cells or embryos may also be developed into transgenic organisms.
FILED Monday, April 19, 2004
APPL NO 10/826523
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Education (ED) 

US 07104659 Grier et al.
FUNDED BY
Department of Education (ED)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) University of Chicago (Chicago, Illinois)
INVENTOR(S) David G. Grier (New York, New York);  Eric R. Dufresne (Arlington, Virginia);  Jennifer E. Curtis (Chicago, Illinois);  Brian A. Koss (Chicago, Illinois)
ABSTRACT A method and apparatus for control of optical trap arrays and formation of particle arrays using light that is in the visible portion of the spectrum. The method and apparatus provides a laser and a time variable diffractive optical element to allow dynamic control of optical trap arrays and consequent control of particle arrays and also the ability to manipulate singular objects using a plurality of optical traps. By avoiding wavelengths associated with strong absorption in the underlying material, creating optical traps with a continuous-wave laser, optimizing the efficiency of individual traps, and trapping extended samples at multiple points, the rate of deleterious nonlinear optical processes can be minimized.
FILED Friday, December 10, 2004
APPL NO 11/010004
ART UNIT 2881 — Optics
CURRENT CPC
Optical: Systems and elements
359/614
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105820 Federici et al.
FUNDED BY
Department of Defense (DOD)
Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC)
Technical Support Working Group (TSWG)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Education (ED)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) John F. Federici (Westfield, New Jersey);  Dale E. Gary (Berkeley Heights, New Jersey)
ABSTRACT Near field imaging using a THz imaging system is realized by utilizing an interferometric imaging detector array that includes detector elements disposed on a surface curved, physically or artificially, to match substantially the curvature of the wave front for received THz signals. Generally, the near field is an environment wherein the distance to an object of interest is on the order of 10–100 times larger than the physical size of the THz imaging array. Typical distances from the object or target to the imaging array is anticipated to be in the 0.5 m–50 m range. Curvature of the detector array corrects a distortion problem in prior THz imaging systems that utilized planar interferometric imaging arrays based on a planar wave front assumption for received THz signals.
FILED Tuesday, January 18, 2005
APPL NO 11/037507
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/339.20
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07106057 Matthews et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) University of Maryland (College Park, Maryland);  National Security Agency (Fort George Meade, Maryland)
INVENTOR(S) John Matthews (Greenbelt, Maryland);  Frederick Charles Wellstood (Fairfax, Virginia);  Soun Pil Kwon (Hyattsville, Maryland);  Kosta P. Vlahacos (Clarksville, Maryland)
ABSTRACT A scanning SQUID microscope capable of high frequency magnetic field measurements uses a hysteretic SQUID detector and a pulsed sampling technique which permits to extend the bandwidth of the SQUID microscope to above GHz region. The system can be readily incorporated into a 4.2k scanning SQUID microscope for imaging chips at room temperature. By biasing the hysteretic SQUID with pulses of a predetermined amplitude, and adjusting a modulation flux applied to the hysteretic SQUID at a plurality of time delays between the activation of the sample under study and the bias pulse, the hysteretic SQUID can be switched on, and the modulation flux value corresponding to such a switching event as a function of time is considered as representation of the magnetic field emanating from the sample under study.
FILED Thursday, March 17, 2005
APPL NO 11/081529
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/248
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07106971 Davis
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Christopher C. Davis (Bowie, Maryland)
ABSTRACT A system and method for optical wireless communication with fading resistance. A delayed diversity approach reduces fading significantly. Data is sent in a set of light signals (also called diverse light signals) which each have a different polarization and/or a different wavelength. The diverse light signals are also temporally different in that they are transmitted in a delayed fashion with respect to one another. In this way, each light signal is carried over a different, uncorrelated “channel” through the atmosphere. At a receiver, original data in each received light signals is temporally adjusted and combined into a single output data signal. The accuracy of each bit in the output data signal is then due to the reception of the combined diverse light signals. In this way, even if fading occurs in one channel (effecting one diverse light signal), a combined output data signal can still be generated at relatively high accuracy from the original data carried in one or more of the other diverse light signals.
FILED Friday, June 30, 2000
APPL NO 10/018957
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/125
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07107144 Capozzi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S) Spectra Research, Inc. (Dayton, Ohio)
INVENTOR(S) Jerry V. Capozzi (Bellbrook, Ohio);  Michael R. Johnson (Beavercreek, Ohio);  Gordon R. Little (Kettering, Ohio);  Paul D. Zidek (Dayton, Ohio)
ABSTRACT A traffic monitoring system including a non-intrusive lane monitor is provided. The lane monitor comprises one or more laser channels, a user interface, and a programmable controller in communication with the laser channels and the user interface. In accordance with one embodiment of the present invention, a pair of laser channels are provided. The first laser axis is substantially parallel to the second laser axis and the first and second laser axes lie substantially in a common horizontal plane. The programmable controller is configured to generate reflected laser pulse count corresponding to reflection of a pulsed laser signal from a target positioned along one of the laser axes and identify the reflected signal as a valid or invalid target by comparing the pulse count to a predetermined valid target count.
FILED Thursday, February 26, 2004
APPL NO 10/787850
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/117
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07104349 Gray, Jr.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the United States Environmental Protection Agency (Washington, District of Columbia)
INVENTOR(S) Charles L. Gray, Jr. (Pinckney, Michigan)
ABSTRACT A Homogenous Charge Compression Ignition (HCCI) engine is used in conjunction with a hybrid powertrain. Power production from the HCCI engine in operation may be decoupled from, or assisted in, responding to driver power demand. In this manner, the HCCI engine: (i) is relieved from the need to quickly adapt to changes in driver power demand, and/or (ii) is allowed to more slowly transition between power levels reflective of the vehicle power demands, with a secondary power source providing the more immediate power response to driver demands. In addition, driver power demand greater than what can be provided by the HCCI engine may preferably be met through the addition of power from the powertrain's reversible secondary power source (e.g. one or more reversible electric motor/generator(s) or reversible hydraulic pump/motor(s)), thereby avoiding the need for full load operation by the HCCI engine. In this manner, driver power demand may be met by the vehicle with commercially acceptable responsiveness, while simultaneously enabling the use of a highly efficient low emission HCCI engine.
FILED Thursday, January 20, 2005
APPL NO 11/039626
ART UNIT 3618 — Printing/Measuring and Testing
CURRENT CPC
Motor vehicles
180/65.400
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07105820 Federici et al.
FUNDED BY
Department of Defense (DOD)
Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC)
Technical Support Working Group (TSWG)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Education (ED)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) John F. Federici (Westfield, New Jersey);  Dale E. Gary (Berkeley Heights, New Jersey)
ABSTRACT Near field imaging using a THz imaging system is realized by utilizing an interferometric imaging detector array that includes detector elements disposed on a surface curved, physically or artificially, to match substantially the curvature of the wave front for received THz signals. Generally, the near field is an environment wherein the distance to an object of interest is on the order of 10–100 times larger than the physical size of the THz imaging array. Typical distances from the object or target to the imaging array is anticipated to be in the 0.5 m–50 m range. Curvature of the detector array corrects a distortion problem in prior THz imaging systems that utilized planar interferometric imaging arrays based on a planar wave front assumption for received THz signals.
FILED Tuesday, January 18, 2005
APPL NO 11/037507
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/339.20
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 07105205 Clayton et al.
FUNDED BY
U.S. State Government
State of New York
APPLICANT(S)
ASSIGNEE(S) Research Foundation of the State of New York (Stony Brook, New York)
INVENTOR(S) Clive Clayton (East Setauket, New York);  Herbert Herman (Port Jefferson, New York);  Henry White (Nesconset, New York)
ABSTRACT A thermal spray mixed with a substrate using a non-consumable cylindrical rotating tool. The process may be repeated to create a composite-like coating or material. The coating or material may be machine to improve surface quality.
FILED Monday, March 29, 2004
APPL NO 10/811610
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating processes
427/446
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07104756 Harding et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Benjamin R. Harding (Ellington, Connecticut);  Eric A. Hudson (Harwinton, Connecticut)
ABSTRACT A vane assembly 10 suitable for a turbine engine features a refractory vane 12 with an internal cavity 20 and a pair of flexible metallic baffles 26 extending into the cavity from spanwisely opposite ends of the vane. A rigid fastener 48, such as a nut and bolt assembly applies a tensile load to the baffles. The tensile load is reacted out as a compressive load applied to the vane. In another embodiment, the baffle is relatively rigid but the fastener is flexible. The compressive loading exerted on the vane counteracts the brittleness customarily exhibited by refractory materials and imparts damage tolerance to the vane. The arrangement also allows the use of a metal baffle that can be easily secured to the vane and dispenses with any need for a potentially troublesome seal between the baffles and the spanwise extremities of the vane.
FILED Wednesday, August 11, 2004
APPL NO 10/916682
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/96.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105643 Lu
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Attorney General of the Dept. of Justice (Washington, District of Columbia)
INVENTOR(S) Natalie T. Lu (Clarksville, Maryland)
ABSTRACT A monoclonal antibody, and a cell line capable of producing the same, has been produced with the ability to detect the primary metabolites generated from the pyrolysis of smokeable, or “crack”, cocaine. This monoclonal antibody, while being highly specific for anhydroecgonine methyl ester (AEME) and ecgonidine (ECD), does not cross-react at a significant level with the primary cocaine metabolites of powdered or injected cocaine. Also, crack cocaine conjugates capable of evoking an immune response in animals have been produced.
FILED Wednesday, July 30, 2003
APPL NO 10/629749
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07105702 Zhang et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Xumu Zhang (State College, Pennsylvania);  Wenjun Tang (State College, Pennsylvania)
ABSTRACT Chiral ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes according to the present invention are useful as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation, isomerization, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition; epoxidation, kinetic resolution and [m+n] cycloaddition. Processes for the preparation of the ligands are also described.
FILED Friday, November 08, 2002
APPL NO 10/291232
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
568/8
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, September 12, 2006.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060912.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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