FedInvent™ Patents

Patent Details for Tuesday, September 19, 2006 

This page was updated on Sunday, March 26, 2023 at 08:05 PM GMT

Department of Defense (DOD) 

US 07107839 Berman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Morris S. Berman (Olney, Maryland);  Jan M. Niemiec (New Market, Maryland)
ABSTRACT A system and method for determining whether leaks exist in a pressure vessel comprises measuring a mechanical response of the pressure vessel using any of an acoustic sensor and a vibration sensor; processing the mechanical response using a digital signal processor system; categorizing the processed mechanical response into events of interest and events not of interest; and determining if any of a ballistic impact and penetration of the pressure vessel has occurred based on the processed mechanical response, wherein the mechanical response comprises any of an acoustic response and a vibration response, wherein the events of interest comprise any of environmental events and ballistic events, wherein the categorizing comprises differentiating the environmental events from the ballistic events, and wherein the events not of interest comprise noise.
FILED Thursday, September 30, 2004
APPL NO 10/953738
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/489
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07107842 Wu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Wei-Chung Wu (Albany, California);  Robert Wood (Berkeley, California)
ABSTRACT An angular rate sensing system suitable for a micromechanical flying insect (MFI) device. The system includes a rod, or haltere, that is moved in a plane by a piezoelectric actuator. Bending of the haltere due to angular movement of a body onto which the haltere is coupled is sensed with a resistive strain gage. In a first embodiment the haltere is actuated (i.e., made to beat or sweep) by simple coupling to an actuator. In a second embodiment, a four-bar structure is used to amplify the motion of a piezoelectric bender to cause haltere beating. Another embodiment achieves haltere beating by parasitic transmission of vibrations of the MFI body to the base of the haltere.
FILED Monday, May 03, 2004
APPL NO 10/838480
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/504.150
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US 07108045 Wiedemer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) John D. Wiedemer (Glastonbury, Connecticut);  Keith A. Santeler (Middletown, Connecticut)
ABSTRACT A composite core for an investment casting process, the core including both a ceramic portion and a refractory metal portion, with the refractory metal portion being so disposed as to perform the function of a plurality of such refractory metal elements. In particular, a refractory metal element attached to a trailing edge of a ceramic element extends beyond the plane of a tip end of the ceramic element so as to replace the refractory metal element otherwise extending from the ceramic tip edge. The refractory metal element also extends beyond the space to be occupied by the wax casting, both in the direction of the tip end and the trailing edge such that improved placement and securing of the core is facilitated during the casting process. A further embodiment uses a single refractory metal element that extends into both the airfoil portion and an orthogonal extending platform portion thereof.
FILED Thursday, September 09, 2004
APPL NO 10/937067
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Metal founding
164/369
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US 07108111 Spyche, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S)
ASSIGNEE(S) Enidine Incorporated (Orchard Park, New York)
INVENTOR(S) Gerald J. Spyche, Jr. (South Wales, New York);  Kenichi Tomita (Williamsville, New York)
ABSTRACT A shock and vibration isolator that includes a double acting mechanical spring assembly that is mounted to act in parallel with a fluid or liquid spring assembly. The mechanical spring is arranged to provide a first spring rate over a first displacement range and a second spring rate over a further second displacement range. The liquid spring is connected to an accumulator by control circuitry that is under the control of a microprocessor to release stored energy which combines with that of the mechanical spring to rapidly dissipate the input G forces to a level sufficient to protect a substructure.
FILED Monday, October 25, 2004
APPL NO 10/972709
ART UNIT 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Brakes
188/378
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US 07108137 Lal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Amit Lal (Ithaca, New York);  Chung Hoon Lee (Ithaca, New York)
ABSTRACT A method and apparatus for separating a mixture of particles of various sizes in a capillary tube into groups by size using multiple forces of controlled amplitude. Ultrasonic radiation at a first selected frequency is applied to set up a standing pressure wave in the capillary tube, resulting in a first aggregating force which causes particles of all sizes to aggregate at positions within the capillary tube which correspond to nodes or anti-nodes of the standing wave. Transverse vibrations are also applied to the capillary tube. The frequency of the ultrasonic radiation is adjusted to reduce the magnitude of the first aggregating force. Inertial forces resulting from the transverse vibrations then cause the particles to separate by size. The apparatus and method allows a mixture of particles to be separated by size quickly, without requiring the use of high voltages.
FILED Wednesday, October 02, 2002
APPL NO 10/263385
ART UNIT 3653 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Classifying, separating, and assorting solids
29/659
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US 07108758 Fallis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stephen Fallis (Ridgecrest, California);  Jennifer A. Irvin (Ridgecrest, California)
ABSTRACT An electrostatic charge reduction system including a composition having at least one energetic particle component with or without a non-conducting binder, and conducting polymer or electrically neutral polymer deposited on the energetic component in its oxidized form. The oxidation of the polymer occurs during or after the polymer deposition process.
FILED Monday, March 17, 2003
APPL NO 10/389608
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive and thermic compositions or charges
149/19.920
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US 07108773 Masel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Richard I. Masel (Champaign, Illinois);  Cynthia A. Rice (Champaign, Illinois)
ABSTRACT A solution useful for forming a solid that supports mass transfer includes carbon nanotubes and a solvent. Solids formed using the solution thereby have carbon nanotubes dispersed therein that are useful for communicating gas and/or electric charges within the solid. Catalyst layers of the invention that include carbon nanotubes can provide high levels of efficiency while requiring low catalyst concentrations.
FILED Wednesday, September 11, 2002
APPL NO 10/241306
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/252
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US 07108782 Higgins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James E. Higgins (Bethesda, Maryland);  John H. Benson (Ellicott City, Maryland);  Peter J. Schauer (Gaithersburg, Maryland);  Jack L. McCrea (Pittsburgh, Pennsylvania)
ABSTRACT Shipboard wastewater undergoes treatment within an automatic system based on membrane bioreactor technology. Bacteria that are naturally present in the raw waste stream break down during treatment and consume organic material in the wastewater. Membranes in a bioreactor within which the wastewater is treated provide a physical barrier, retaining the bacteria and other solids while producing an effluent sufficiently clean to be discharged directly overboard. To ensure adequate treatment, a flow-through ultraviolet disinfection unit is employed in the system downstream of filtration. Inorganic and other non-biodegradable material that accumulates in the bioreactor with time is removed automatically to maintain the desired solids concentration in the bioreactor. Using selective control established through the operator interface, the system can be operated under automatic process/standby mode or maintenance mode, and sludge concentrate can be directed either overboard, to an onboard storage tank or to undergo further treatment within a concentration device or destruction within an incinerator for example, depending on the ship's equipment, location and operating conditions.
FILED Friday, June 27, 2003
APPL NO 10/607143
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/151
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US 07108894 Renn
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Optomec Design Company (Albuquerque, New Mexico)
INVENTOR(S) Michael J. Renn (Albuquerque, New Mexico)
ABSTRACT Methods and apparatus for the deposition of a source material (10) are disclosed. An atomizer (12) renders a supply of source material (10) into many discrete particles. A force applicator (14) propels the particles in continuous, parallel streams of discrete particles. A collimator (16) controls the direction of flight of the particles in the stream prior to their deposition on a substrate (18). In an alternative embodiment of the invention, the viscosity of the particles may be controlled to enable complex depositions of non-conformal or three-dimensional surfaces. The invention also includes a wide variety of substrate treatments which may occur before, during or after deposition. In yet another embodiment of the invention, a virtual or cascade impactor may be employed to remove selected particles from the deposition stream.
FILED Tuesday, February 05, 2002
APPL NO 10/072605
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Coating processes
427/596
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US 07108940 Sharrow et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joseph F. Sharrow (Fredericksburg, Virginia);  Kurt W. Solomon (Fredericksburg, Virginia);  Frank E. Peterkin (Fredericksburg, Virginia);  Jack S. Bernardes (King George, Virginia);  Brian J. Hankla (King George, Virginia)
ABSTRACT A battery mechanism is disclosed. The battery mechanism in one embodiment includes battery assemblies, a switching mechanism, and an actuating mechanism. The battery assemblies are removably mounted to the switching mechanism. The switching mechanism has a non-energized position in which the battery assemblies are electrically disconnected from the switching mechanism. The switching mechanism also has an energized position in which the battery assemblies are electrically connected to the switching mechanism. The actuating mechanism is connected to the switching mechanism, and switches the switching mechanism between the non-energized and the energized positions. The actuating mechanism preferably is activated remotely, improving personnel safety. The number and make-up of the battery assemblies may be varied to provide for different voltages.
FILED Friday, May 16, 2003
APPL NO 10/457698
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/97
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US 07108974 Ecker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Isis Pharmaceuticals, Inc. (Carlsbad, California)
INVENTOR(S) David J. Ecker (Encinitas, California);  Richard Griffey (Vista, California);  Rangarajan Sampath (San Diego, California);  Steven Hofstadler (Oceanside, California);  John McNeil (La Jolla, California)
ABSTRACT Method for detecting and identifying unknown bioagents, including bacteria, viruses and the like, by a combination of nucleic acid amplification and molecular weight determination using primers which hybridize to conserved sequence regions of nucleic acids derived from a bioagent and which bracket variable sequence regions that uniquely identify the bioagent. The result is a “base composition signature” (BCS) which is then matched against a database of base composition signatures, by which the bioagent is identified.
FILED Friday, May 24, 2002
APPL NO 10/156608
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07109007 Peoples et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Oliver P. Peoples (Arlington, Massachusetts);  Anthony J. Sinskey (Boston, Massachusetts)
ABSTRACT A method for controlling and modifying biopolymer synthesis by manipulation of the genetics and enzymology of synthesis of polyhydroxybutyrate (PHB) and polyhydroxyalkanoate (PHA) polyesters at the molecular level in procaryotic and eukaryotic cells, especially plants. Examples demonstrate the isolation, characterization, and expression of the genes involved in the production of PHB and PHA polymers. Genes encoding the enzymes in the PHB and PHA synthetic pathway (beta-ketothiolase, acetoacetyl-CoA reductase and PHB polymerase or PHA polymerase) from Zoogloea ramigera strain I-16-M, Alcaligenes eutrophus, Nocardia salmonicolur, and Psuedomonas olevarans were identified or isolated and expressed in a non-PHB producing organism, E. coli. Specific modifications to the polymers include variation in the chain length of the polymers and incorporation of different monomers into the polymers to produce co-polymers with different physical properties.
FILED Tuesday, March 22, 2005
APPL NO 11/086605
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/175
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US 07109107 Prather et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) University of Delaware (Newark, Delaware)
INVENTOR(S) Dennis W. Prather (Newark, Delaware);  Saurabh Lohokare (Newark, Delaware)
ABSTRACT A method for fabricating a flip-chip semiconductor device having plural conductive polymer bumps includes forming plural molds on a substrate using a photolithographic technique; filling the molds by applying and spinning a layer of conductive polymer material onto the substrate; polishing the conductive polymer material layer to remove excess conductive material from a surface of the substrate; and stripping the plural molds from the substrate to reveal the plural bumps. In various aspects of disclosure, either positive resist or negative resist may be used. The electrical contact resistance compares favorably with squeegee-based bumps; there is an improvement in the contact resistance of the bumps patterned using polishing techniques in comparison to that of squeegee-based conductive polymer bumps.
FILED Monday, August 09, 2004
APPL NO 10/710870
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/614
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US 07109136 Senecal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kris Senecal (N. Smithfield, Rhode Island);  Lynne Samuelson (Marlborough, Massachusetts);  Michael Sennett (Sudbury, Massachusetts);  Heidi Schreuder-Gibson (Holliston, Massachusetts)
ABSTRACT A conductive (electrical, ionic, and photoelectric) polymer membrane article, comprising a non-woven membrane of polymer fibers, wherein at least some of the fibers have diameters of less than one micron; and wherein the membrane has an electrical conductivity of at least about 10−6 S/cm. Also disclosed is the method of making such an article, comprising electrostatically spinning a spin dope comprising a polymer carrier and/or a conductive polymer or conductive nanoparticles, to provide inherent conductivity in the article.
FILED Tuesday, November 25, 2003
APPL NO 10/722213
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Fabric
442/347
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US 07109359 Dave et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Paritosh R. Dave (Bridgewater, New Jersey);  Raja G. Duddu (Parsipanny, New Jersey);  Reddy Damavarapu (Hackettstown, New Jersey);  Nathaniel Gelber (Randolph, New Jersey);  Kathy Yang (Flanders, New Jersey);  C. Rao Surapaneni (Long Valley, New Jersey)
ABSTRACT The invention relates to a novel polyazido compound: 2,2-dinitro-1,3-diazidopropane.
FILED Friday, August 15, 2003
APPL NO 10/604774
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
552/11
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US 07109488 Milton
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) A. Fenner Milton (Washington, District of Columbia)
ABSTRACT A multi-color IR imaging device includes optics that direct mid-wave infrared (MWIR) and long-wave infrared (LWIR) radiation onto a focal plane array having LWIR and MWIR detection layers. Pixel groups that include at least one first pixel and one second pixel are defined on the focal plane array, and a first filter and a second filter which form part of an inhomogeneous filter is placed over the respective first and second pixels in a checkerboard pattern, in close proximity to the detection layers. This allows MWIR radiation in M band, and LWIR radiation in an L1 band to pass therethrough and illuminate the first pixels, and M, L1, and a separate LWIR band designated L2 to pass therethrough and illuminate the second pixels. To simultaneously image both MWIR and LWIR, the focal plane array is placed at a predetermined distance from the optics so that the MWIR spot size covers a single pixel and the LWIR spot size is about the same area as the area of a group of two first pixels and two second pixels. Since all pixels receive the M band, half of the pixels in the group receive the L1 band, and the other half receives the L2 band, three bands can be generated. This allows simultaneous imaging of MWIR and two sub-bands of the LWIR from the same point in space.
FILED Thursday, February 26, 2004
APPL NO 10/787907
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/332
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US 07109517 Zaidi
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Saleem H. Zaidi (Albuquerque, New Mexico)
ABSTRACT Subwavelength random and periodic microscopic structures are used to enhance light absorption and tolerance for ionizing radiation damage of thin film and photodetectors. Diffractive front surface microscopic structures scatter light into oblique propagating higher diffraction orders that are effectively trapped within the volume of the photovoltaic material. For subwavelength periodic microscopic structures etched through the majority of the material, enhanced absorption is due to waveguide effect perpendicular to the surface thereof. Enhanced radiation tolerance of the structures of the present invention is due to closely spaced, vertical sidewall junctions that capture a majority of deeply generated electron-hole pairs before they are lost to recombination. The separation of these vertical sidewall junctions is much smaller than the minority carrier diffusion lengths even after radiation-induced degradation. The effective light trapping of the structures of the invention compensates for the significant removal of photovoltaic material and substantially reduces the weight thereof for space applications.
FILED Friday, November 15, 2002
APPL NO 10/298694
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/22
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US 07109521 Hallin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Christer Hallin (Linkoping, Sweden);  Heinz Lendenmann (Stocksund, Sweden);  Joseph John Sumakeris (Apex, North Carolina)
ABSTRACT An epitaxial silicon carbide layer is fabricated by forming first features in a surface of a silicon carbide substrate having an off-axis orientation toward a crystallographic direction. The first features include at least one sidewall that is orientated nonparallel (i.e., oblique or perpendicular) to the crystallographic direction. A first epitaxial silicon carbide layer is then grown on the surface of the silicon carbide substrate that includes first features therein. Second features are then formed in the first epitaxial layer. The second features include at least one sidewall that is oriented nonparallel to the crystallographic direction. A second epitaxial silicon carbide layer is then grown on the surface of the first epitaxial silicon carbide layer that includes the second features therein.
FILED Monday, August 30, 2004
APPL NO 10/929911
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/77
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US 07109872 Balaban et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Carey David Balaban (Pittsburgh, Pennsylvania);  Mark Steven Redfern (Pittsburgh, Pennsylvania)
ABSTRACT A postural assessment chair provides a device for monitoring the posture of an individual seated thereon, and correlating changes in the individual's posture, along with indicia of movement of the chair itself and the cognitive workload of the individual, to determine the mental engagement of the individual.
FILED Thursday, May 06, 2004
APPL NO 10/840791
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/573.700
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US 07109909 Gounalis
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Anthony J. Gounalis (Endicott, New York)
ABSTRACT A system in accordance with the present invention determines signal attenuation for an electronic support measure receiver. The system includes a detection module for receiving electromagnetic signals from a surrounding environment and a processing module for chronologically segregating the electromagnetic signals into a plurality of dwells. The processing module controls the processing of the plurality of dwells. The processing module determines an analysis dwell from the plurality of dwells. The processing module computes a coarse attenuation for the analysis dwell. The processing module further computes a fine attenuation from the coarse attenuation and an offset table value.
FILED Thursday, March 11, 2004
APPL NO 10/798612
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/13
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US 07109918 Meadows et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brian K. Meadows (San Diego, California);  Ted H. Heath (Marietta, Georgia);  Joseph D. Neff (San Diego, California);  Edgar A. Brown (Atlanta, Georgia);  David W. Fogliatti (Carlsbad, California);  Visarath In (Chula Vista, California);  Paul Hasler (Atlanta, Georgia);  Steve P. DeWeerth (Marietta, Georgia);  William L. Ditto (Gainesville, Florida);  Robert A. York (Goleta, California)
ABSTRACT This invention exploits the synchronization properties of coupled, nonlinear oscillators arrays to perform power combining, beam steering, and beam shaping. This architecture utilizes interactions between nonlinear active elements to generate beam patterns. A nonlinear array integrates the signal processing concurrently with the transduction of the signal. This architecture differs fundamentally from passive transducer arrays in three ways: 1) the unit cells are nonlinear, 2) the array purposely couples the unit cells together, and 3) the signal processing (beam steering and shaping) is done via dynamic interactions between unit cells. The architecture extends to both 1- and 2-dimensional arrays.
FILED Friday, May 23, 2003
APPL NO 10/446287
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/368
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US 07109928 Thiele et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Gary A. Thiele (Dayton, Ohio);  Dan S. Janning (Dayton, Ohio)
ABSTRACT A microwave radio frequency bidirectional energy flow-capable antenna method and related antenna of the physically conformal microstrip transmission line, traveling wave and leaky wave characterizations; the antenna is especially suited to vehicle mounting. The disclosed antenna operates in an EH1 or other above dominant mode energy wave propagation configuration, a configuration at least partially achieved by an array of selected-location radiating element shortings to an antenna-underlying transmission line ground plane element. Comparisons of the disclosed antenna with characteristics of a similarly classified antenna of somewhat lesser desirable but know characteristics are included.
FILED Wednesday, March 30, 2005
APPL NO 11/101662
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/700.MS0
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US 07109929 Ryken, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Marvin L. Ryken, Jr. (Oxnard, California);  Albert F. Davis (Ventura, California)
ABSTRACT A TM microstrip antenna designed to transmit telemetry data for use by a fourteen inch diameter projectile. The microstrip antenna is configured to wrap around the projectile's body without interfering with the aerodynamic design of the projectile. The TM microstrip antenna operates at the 2200 to 2300 MHz TM frequency band. Eight microstrip antenna elements equally spaced around the projectile provide for linear polarization and a quasi-omni directional radiation pattern.
FILED Wednesday, June 01, 2005
APPL NO 11/145234
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/700.MS0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109942 McCarville et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Douglas A. McCarville (Auburn, Washington);  Gerald F. Herndon (Redmond, Washington);  Joseph A. Marshall, IV (Lake Forest Park, Washington);  Robert G. Vos (Auburn, Washington);  Isaac R. Bakker (Seattle, Washington);  David L. Banks (Bellevue, Washington)
ABSTRACT An antenna aperture and method of assembling same. The antenna aperture forms a honeycomb-like core structure with dipole radiating elements integrally formed into structural wall portions of the honeycomb-like core. The antenna aperture has sufficient structural strength to form a structural portion of a mobile platform, while still being sufficiently light in weight for weight-critical applications such as with airborne mobile platforms.
FILED Thursday, October 21, 2004
APPL NO 10/970702
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/797
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110118 Ünlü et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Selim M. Ünlü (Jamaica Plain, Massachusetts);  Anna Swan (Cambridge, Massachusetts);  Bennett B. Goldberg (Newton, Massachusetts);  Stephen Ippolito (Tampa, Florida);  Lev Moiseev (Brighton, Massachusetts);  Samuel Lipolf (Newton, Massachusetts);  Yunjie Tong (Allston, Massachusetts)
ABSTRACT A method and apparatus for performing optical microscopy in one to three dimensions employs a spectral self-interference fluorescent microscopy technique that includes providing at least one fluorescent microscopy sample, at least one objective lens, and at least one reflecting surface. The fluorescent sample is disposed between the objective lens and the reflecting surface, the distance from the sample to the reflecting surface being several to several tens times an excitation wavelength. Excitation light causes the fluorescent sample to emit light, at least a portion of which is reflected by the reflecting surface. The objective lens collects the reflected light and the light emitted directly by the fluorescent sample. The direct and reflected light interfere causing spectral oscillations in the emission spectrum. The periodicity and the peak wavelengths of the emission spectrum are spectroscopically analyzed to determine the optical path length between the fluorescent sample and the reflecting surface.
FILED Wednesday, December 19, 2001
APPL NO 10/451096
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
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US 07110602 Krause
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Larry G. Krause (Tucson, Arizona)
ABSTRACT An edge detection system and method implement a recursive polar algorithm process to generate an edge image from an input image. The edge detection system may include a polar filter to recursively perform low-pass filtering along edge contours of a gradient pixel grid and generate a gradient image output. An edge thinner may be included to find gradient field peaks along a direction of gradient vectors of the gradient image output and generate thinned gradient pixels. An edge path segmenter may group the thinned gradient pixels into edge segments, and a segment classifier may determine whether the edge segments are edge paths or clutter. The edge detection system and method may improve automated image processing in medical diagnostics, reconnaissance, missile guidance, hazard or threat warning systems, security systems, access control systems (e.g., face recognition), navigation, geographic mapping, manufacturing quality inspection, robot vision, and search and rescue.
FILED Wednesday, August 21, 2002
APPL NO 10/224866
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/199
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US 07110678 Willebrand et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S)
ASSIGNEE(S) LightPointe Communications, Inc. (San Diego, California)
INVENTOR(S) Heinz Willebrand (Longmont, Colorado);  Maha Achour (San Diego, California)
ABSTRACT A hybrid wireless optical and radio frequency (RF) communication link utilizes parallel free-space optical and RF paths for transmitting data and control and status information. The optical link provides the primary path for the data, and the RF link provides a concurrent or backup path for the network data, as well as a reliable and primary path for the control and status information. When atmospheric conditions degrade the optical link to the point at which optical data transmission fails, the hybrid communication link switches to the RF link to maintain availability of data communications. The switch may occur automatically, based on an assessment of the quality of the optical signal communicated through the optical path.
FILED Wednesday, May 05, 2004
APPL NO 10/840172
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/115
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US 07110891 Tarr
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Paulo Bertell Tarr (Silver Spring, Maryland)
ABSTRACT Magnetic signature measurements are taken at various points corresponding to an original water depth beneath a ship. A computer processor receives and processes (i) this group of measured magnetic signature values and (ii) the designed magnetic signature value the sensing of which actuates the subject magnetic mine, implementing graph display management on a user interface display screen. According to the computer processing, some or all such measured magnetic signature values are extrapolated at different depths each greater than the original depth, thereby yielding several or many groups, each group being of extrapolated magnetic signature values associated with various points corresponding to the same depth, the groups collectively representing a three-dimensional arrangement of extrapolated magnetic signature values associated with various points corresponding to different depths. Each point is characterized as either actuating or non-actuating of the mine, and various perspectives of some or all such characterizations are displayed.
FILED Friday, November 08, 2002
APPL NO 10/292930
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/38
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US 07110946 Belenger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert V. Belenger (Raynham, Massachusetts);  Gennaro R. Lopriore (Somerset, Massachusetts)
ABSTRACT A speech to visual display translator assembly and method for converting spoken words directed to an operator into essentially simultaneous visual displays wherein the spoken words are presented in phonems and variations in loudness and tone, and/or other characteristics of phonemes displayed, are presented visually by the display.
FILED Tuesday, November 12, 2002
APPL NO 10/292955
ART UNIT 2626 — Selective Visual Display Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/235
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE39298 MacPhee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The American National Red Cross (Rockville, Maryland)
INVENTOR(S) Martin J. MacPhee (Montgomery Village, Maryland);  William N. Drohan (Springfield, Virginia);  Gene Liau (Darnestown, Maryland);  Hernan Nunez (Derwood, Maryland);  Wilson H. Burgess (Clifton, Virginia);  Thomas Maciag (Freeport, Maine);  Manish Singh (San Diego, California)
ABSTRACT This invention provides methods for the localized delivery of supplemented tissue sealants, wherein the supplemented tissue sealants comprise at least one composition which is selected from one or more antibodies, analgesics, anticoagulants, anti-inflammatory compounds, antimicrobial compositions, antiproliferatives, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like. Further provided are methods of using the site-specific supplemented tissue sealants, including preparation of a biomaterial.
FILED Friday, June 20, 2003
APPL NO 10/465860
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/426
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Department of Health and Human Services (HHS) 

US 07107987 Sundaram et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) CFD Research Corporation (Huntsville, Alabama)
INVENTOR(S) Shivshankar Sundaram (Madison, Alabama);  Balabhaskar Prabhakarpandian (Madison, Alabama);  Vinod Makhijani (Guilford, Connecticut);  Andrzej Przekwas (Huntsville, Alabama)
ABSTRACT A spacer for delivering a medication spray from an inhaler includes a first conical body joined to a second conical body, forming a continuous spray conduit through first and second internal chambers of the respective first and second conical bodies. A mouthpiece is formed in the proximal end of the first conical body. A spray inlet for attachment to the inhaler is formed at the distal end of the second conical body. A plurality of air inlets are placed downstream of the medication inlet proximate to, or in, the large diameter distal end surface of the first conical body. Recirculation zones are created in the first and second chambers, to force the medication spray into a central airflow path through the spray conduit, minimizing particle deposition by contract with the walls of the spacer.
FILED Tuesday, February 10, 2004
APPL NO 10/775465
ART UNIT 3743 — Printing/Measuring and Testing
CURRENT CPC
Surgery
128/200.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07107991 Kolobow
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Theodor Kolobow (Rockville, Maryland)
ABSTRACT A tracheal tube ventilation apparatus to more effectively remove expired gases. In one preferred embodiment, one or more leak holes are created in the side walls of an endotracheal tube so that expired gases can leak out of the endotracheal tube above the larynx, such as into the back of the mouth (i.e., oropharynx). Each leak hole might advantageously have a diameter between 0.5 and 4.0 mm. In another preferred embodiment, a tube is attached to a proportionately larger leak hole (e.g., up to 8.0 mm) so that the expired gases can be directed away from the leak hole to a specific location, such as directed out of the mouth. In the case of mechanically controlled ventilation, a positive end expiratory pressure can be applied to this tube to mechanically assist with the process of exhaling. In each of these embodiments, it is preferred, but not required, that the endotracheal tube be an ultra-thin walled, two stage tube so as to further assist in the reduction of resistance to the flow of oxygen/air.
FILED Friday, September 28, 2001
APPL NO 09/967903
ART UNIT 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
128/207.140
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108688 Jensen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Joel F. Jensen (Redwood City, California)
ABSTRACT The invention is directed to a remote center positioner used to support an instrument and provide a center of spherical rotation, remote from any bearings or mechanical supports, at a desired location of the instrument. The remote center positioner is particularly useful in laparoscopic surgery to constrain a surgical instrument to move around a fixed center of rotation remote from any bearings or mechanical supports and coincident with an entry incision in the abdominal wall.
FILED Tuesday, June 15, 2004
APPL NO 10/868388
ART UNIT 3739 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Surgery
66/1
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US 07108801 Wellinghoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) Southwest Reasearch Institute (San Antonio, Texas)
INVENTOR(S) Stephen T. Wellinghoff (San Antonio, Texas);  Douglas P. Hanson (San Antonio, Texas)
ABSTRACT A method for producing a blend comprising randomly substituted mesogens comprising: providing one or more platform molecules have the following general structure:
wherein at least one member selected from the group consisting of X and Y comprises one or more spacer groups; R2 is a bulky organic group whereby, when both X and Y are reacted with polymerizable groups to produce polymerizable mesogens, R2 provides sufficient steric hindrance to achieve a nematic state at room temperature while suppressing crystallinity of the polymerizable mesogens at room temperature; and, R1 and R3 are selected from groups less bulky than R2; and independently substituting at least one member selected from the group consisting of X and Y with a polymerizable group, thereby producing a blend of randomly substituted mesogens.
FILED Wednesday, January 23, 2002
APPL NO 10/057506
ART UNIT 1756 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compositions
252/299.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108968 Gingeras et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Affymetrix, Inc. (Santa Clara, California)
INVENTOR(S) Thomas R. Gingeras (Santa Clara, California);  Jorg Drenkow (Hollister, California)
ABSTRACT This invention provides polynucleotide probes, sequences and methods for speciating and phenotyping organisms, for example, using probes based on the Mycobacterium tuberculosis rpoB gene. The groups or species to which an organism belongs may be determined by comparing hybridization patterns of target nucleic acid from the organism to hybridization patterns in a database.
FILED Friday, April 02, 1999
APPL NO 09/285306
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108969 Warrington et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) Affymetrix, Inc. (Santa Clara, California);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Janet A. Warrington (Los Altos, California);  David T. W. Wong (Newton, Massachusetts);  Charles Randolph Todd (Boxford, Massachusetts);  Mamatha Mahadevappa (Cupertino, California)
ABSTRACT Methods of monitoring the expression of genes in malignant oral cells is disclosed. Gene expression profiles are used to identify markers associated with malignant oral cells and to diagnose oral cancer.
FILED Monday, September 10, 2001
APPL NO 09/950016
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108975 Fink et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) John K. Fink (Ann Arbor, Michigan);  Xinping Zhao (Houston, Texas)
ABSTRACT The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
FILED Thursday, September 12, 2002
APPL NO 10/242008
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108981 Aoki et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Yoshiyasu Aoki (Bethesda, Maryland);  Giovanna Tosato (Bethesda, Maryland)
ABSTRACT A specific binding agent is provided, wherein the specific binding agent specifically binds Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin-6 (vIL-6), and the specific binding agent neutralizes an activity of vIL-6. In one embodiment, the specific binding agent is an antibody. Methods are provided for using a specific binding agent that binds vIL-6, and neutralizes a biological activity of vIL-6. Methods of treatment for a KSHV-associated disorder are also provided. Methods for diagnosing a KSHV-associated disorder are provided, as are kits that include a specific binding agent of the invention. A method is also provided for testing an agent for effectiveness in treating a KSHV-associated disorder. The method includes incubating the agent with a cell free system comprising a vIL-6 receptor component and vIL-6, and comparing the binding of vIL-6 and the receptor component in the presence of the agent to binding of vIL-6 to the receptor component in the absence of the agent. A decrease in the binding of vIL-6 to the receptor component in the presence of the agent indicates that the agent is effective for treating the KSHV-associated disorder.
FILED Thursday, July 14, 2005
APPL NO 11/183336
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108984 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Mount Sinai School of Medicine (New York, New York)
INVENTOR(S) Ming-Ming Zhou (Greenwich, Connecticut);  Mitchell Goldfarb (River Edge, New Jersey)
ABSTRACT The present invention provides fragments of SNT and FGFR which can form a binding complex that is amenable to structural determinations by NMR spectroscopy. The three-dimensional structural data is also included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the fragments are also provided.
FILED Tuesday, January 09, 2001
APPL NO 09/757415
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108992 Kastan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S) Michael B. Kastan (Cordova, Tennessee);  Christopher Bakkenist (Cordova, Tennessee)
ABSTRACT The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.
FILED Wednesday, November 27, 2002
APPL NO 10/307077
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109007 Peoples et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Oliver P. Peoples (Arlington, Massachusetts);  Anthony J. Sinskey (Boston, Massachusetts)
ABSTRACT A method for controlling and modifying biopolymer synthesis by manipulation of the genetics and enzymology of synthesis of polyhydroxybutyrate (PHB) and polyhydroxyalkanoate (PHA) polyesters at the molecular level in procaryotic and eukaryotic cells, especially plants. Examples demonstrate the isolation, characterization, and expression of the genes involved in the production of PHB and PHA polymers. Genes encoding the enzymes in the PHB and PHA synthetic pathway (beta-ketothiolase, acetoacetyl-CoA reductase and PHB polymerase or PHA polymerase) from Zoogloea ramigera strain I-16-M, Alcaligenes eutrophus, Nocardia salmonicolur, and Psuedomonas olevarans were identified or isolated and expressed in a non-PHB producing organism, E. coli. Specific modifications to the polymers include variation in the chain length of the polymers and incorporation of different monomers into the polymers to produce co-polymers with different physical properties.
FILED Tuesday, March 22, 2005
APPL NO 11/086605
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/175
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109011 Weigel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Paul H. Weigel (Edmond, Oklahoma);  Kshama Kumari (Oklahoma City, Oklahoma);  Paul DeAngelis (Edmond, Oklahoma)
ABSTRACT The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Streptococcus equisimilis hyaluronate synthase (seHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan.
FILED Tuesday, December 11, 2001
APPL NO 10/011771
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/193
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109019 Shen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ben Shen (Davis, California);  Wen Liu (Beijing, China PRC);  Steven D. Christenson (Davis, California);  Scott Standage (Herts, United Kingdom)
ABSTRACT This invention provides nucleic acid sequences and characterization of the gene cluster responsible for the biosynthesis of the enediyne C-1027 (produced by Streptomyces globisporus). The pathway comprises a nonriobsomal peptide synthetase (NRPS). Methods are provided for the biosynthesis of enediynes, enediyne analogs and other biological molecules.
FILED Friday, May 31, 2002
APPL NO 10/159257
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109041 Sklar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Non-Profit Organization (NPO)
American Heart Association (AHA)
APPLICANT(S)
ASSIGNEE(S) Science and Technology Corporation @University of New Mexico (Albuquerque, New Mexico)
INVENTOR(S) Larry Sklar (Albuquerque, New Mexico);  Eric Prossnitz (Albuquerque, New Mexico);  Vilven Janeen (Albuquerque, New Mexico);  Donna Neldon (Los Lunas, New Mexico)
ABSTRACT A display and method of preparing 7-transmembrane and other receptors for real-time kinetic analysis of binding interactions. The invention includes display on beads and in micelles for multi-well and flow cytometric analysis. The invention is useful for ligand discovery and drug action discovery, and G-protein response in particular.
FILED Thursday, March 21, 2002
APPL NO 10/101870
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/501
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109169 Hobai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Ion A. Hobai (Cambridge, Massachusetts);  Brian O'Rourke (Sparks, Maryland)
ABSTRACT The present invention discloses a method of enhancing cardiac contractility in a subject with heart failure. The method consists of administering a compound that inhibits the sarcolemmal sodium/calcium exchanger, whose activity is elevated in heart failure. This method results in correction of cellular calcium handling and enhancement of cardiac contractility to healthy levels. This method can be used for treatment of acute heart failure, cardiogenic shock and congestive heart failure.
FILED Monday, June 30, 2003
APPL NO 10/610735
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109170 Bajaj et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Saint Louis University (St. Louis, Missouri)
INVENTOR(S) Paul S. Bajaj (St. Louis, Missouri);  Amy E. Schmidt (St. Louis, Missouri)
ABSTRACT Novel polypeptides or derivatives comprising the factor VIIIa binding site on factor IXa are disclosed. The novel polypeptides or derivatives have anti-coagulation activity. Nucleic acids encoding those polypeptides are also disclosed. Methods for identifying an agent having anti-coagulation activity are also disclosed. These methods comprise determining whether the agent displaces the polypeptide or derivative from its factor VIIIa binding site. The agent identified in these methods is also useful in methods for treating a patient to prevent thrombosis. The treatment methods comprise administration of the agent to the patient. Additional methods are also disclosed for treating a patient to prevent thrombosis, comprising treating the patient with a polypeptide or derivative comprising the factor VIIIa binding site on factor IXa. Methods of preventing coagulation in a blood sample are also disclosed, comprising adding the polypeptides or derivatives described above to the blood sample. Methods of detecting factor VIIIa in a sample are also disclosed. Those methods comprise contacting the sample with the above-described polypeptide or derivative, wherein the polypeptide or derivative also comprises a covalently attached detectable moiety, then determining whether the polypeptide or derivative is binding factor VIIIa from the sample.
FILED Monday, September 15, 2003
APPL NO 10/662784
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109177 Priebe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Houston Pharmaceuticals, Inc. (Houston, Texas)
INVENTOR(S) Waldeman Priebe (Houston, Texas);  Izabella Fokt (The Woodlands, Texas);  Teresa Przewloka (Burlington, Massachusetts);  Marta Krawczyk (Greenfield, Wisconsin);  Piotr Skibicki (Warsaw, Poland);  Grzegorz Grynkiewicz (Lominaki, Poland);  Roman Perez-Soler (New York, New York)
ABSTRACT The present invention discloses new and novel substituted anthracyclines with modified alkyl-aromatic ring substitutions on the C-3′ of the sugar moiety or modified or unmodified alkyl-aromatic ring substitutions at the C-4′ of the sugar moiety. It also discloses novel methods for the preparation of sugar substrates and methods for the preparation of anthracycline antibiotics. These anthracycline analogs show high cytotoxicity in vitro against several tumor cell lines.
FILED Tuesday, January 06, 2004
APPL NO 10/752426
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/34
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US 07109235 Ghosh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University Illinois (Urbana, Illinois)
INVENTOR(S) Arun K. Ghosh (River Forest, Illinois)
ABSTRACT Laulimalide and epothilone derivatives useful as microtubule stabilizing agents, and in the treatment of cancers are disclosed. Methods of making the compounds and using the compounds as therapeutic agents in treating cancers also are disclosed.
FILED Wednesday, March 05, 2003
APPL NO 10/382261
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/450
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US 07109244 Rinehart et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Kenneth L. Rinehart (Urbana, Illinois);  Robert A. Warwick (Urbana, Illinois);  Jesus Avila (28002 Madrid, Spain);  Nancy L. Fregeau Gallagher (Wheeling, Illinois);  Dolores Garcia Gravalos (28006 Madrid, Spain);  Glynn T. Faircloth (Cambridge, Massachusetts)
ABSTRACT Investigation of the activity of extracts of the clam Spisula polynyma has led to antitumor long-chain, straight-chain alkane or alkene compounds which have a 2-amino group and a 3-hydroxy group. The present invention is directed to compositions and methods comprising an isolated and purified long-chain, straight-chain 2-amino-3-hydroxyalkane, or prodrug thereof, and a pharmaceutically acceptable carrier, wherein the carbon chain in the long-chain, straight-chain 2-amino-3-hydroxyalkane is C16–C24.
FILED Thursday, October 23, 2003
APPL NO 10/693174
ART UNIT 1614 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/667
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US 07109245 Kunos et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  Organix Inc. (Woburn, Massachusetts)
INVENTOR(S) George Kunos (Bethesda, Maryland);  Raj K. Razdan (Gloucester, Massachusetts)
ABSTRACT Methods and compounds for reversing pathological vasodilation of blood vessels, for example vasodilation caused by activation of CB1-like receptors, by administering to a subject a therapeutically effective amount of a compound sufficient to induce vasoconstriction, the compound comprising:
wherein dashed lines independently represent either a single or a double bond, R1 is a lower alkyl, R2 is a lower alkyl, R3 is a lower alkyl or halogen, R4 is a lower alkyl or hydrogen, R5 is a lower alkyl or hydrogen, R6 is a hydrogen, lower alkyl or halogen, and R7 is a hydrogen, lower alkyl or halogen. The vasoconstrictor can be used for a variety of purposes, including hemostasis or the treatment of shock, for example vasodilatory shock syndromes such as septic shock.
FILED Wednesday, August 14, 2002
APPL NO 10/486810
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/715
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US 07109312 Cook et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Biosearch Technologies, Inc. (Novato, California)
INVENTOR(S) Ronald M. Cook (Novato, California);  Matt Lyttle (Point Reyes Station, California);  Daren Dick (San Geronimo, California)
ABSTRACT The present invention provides a family of dark quenchers, termed Black Hole Quenchers (“BHQs”), that are efficient quenchers of excited state energy but which are themselves substantially non-fluorescent. Also provided are methods of using the BHQs, probes incorporating the BHQs and methods of using the probes.
FILED Friday, July 29, 2005
APPL NO 11/192705
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
534/558
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US 07109317 Clemons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Paul A. Clemons (Somerville, Massachusetts);  Brian G. Gladstone (Dorchester, Massachusetts);  Abhinav Seth (Tenafly, New Jersey);  Stuart L. Schreiber (Boston, Massachusetts)
ABSTRACT Materials and methods are disclosed for regulation of biological events such as target gene transcription and growth, proliferation or differentiation of engineered cells.
FILED Friday, November 05, 1999
APPL NO 09/435257
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.400
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US 07109323 Plamondon et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  Millennium Pharmaceutical, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Louis Plamondon (Watertown, Massachusetts);  Louis Grenier (Cambridge, Massachusetts);  Julian Adams (Brookline, Massachusetts);  Shanker Lal Gupta (Rockville, Maryland)
ABSTRACT The invention relates to the formulation of pharmaceutical compounds. More particularly, the invention provides stable, pharmaceutically acceptable compositions prepared from boronic acid compounds and methods for preparing the compositions. The invention also provides novel boronate ester compounds. The invention further provides boronic acid anhydride compounds useful in the methods of the invention.
FILED Tuesday, December 23, 2003
APPL NO 10/744843
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/53
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US 07109331 Furneaux et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Industrial Research Limited (Auckland, New Zealand);  Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S) Richard Hubert Furneaux (Wellington, New Zealand);  Peter Charles Tyler (Wellington, New Zealand);  Vern L. Schramm (New Rochelle, New York)
ABSTRACT The present invention provides a compound of the formula (I):
wherein A is selected from N, CH and CR, where R is selected from halogen, optionally substituted alkyl, aralkyl and aryl, OH, NH2, NHR1, NR1R2 and SR3, where R1, R2 and R3 are each optionally substituted alkyl, aralkyl or aryl groups; B is selected from OH, NH2, NHR4, H and halogen, where R4 is an optionally substituted alkyl, aralkyl or aryl group; D is selected from OH, NH2, NHR5, H, halogen and SCH3, where R5 is an optionally substituted alkyl, aralkyl or aryl group; X and Y are independendy selected from H, OH and halogen, with the proviso that when one of X and Y is hydroxy or halogen, the other is hydrogen; Z is OH, or, when X is hydroxy, Z is selected from hydrogen, halogen, hydroxy, SQ and OQ, where Q is an optionally substituted alkyl, aralkyl or aryl group; and W is OH or H, with the proviso that when W is OH, then A is CR where R is as defined above; or a tautomer thereof; or a pharmaceutically acceptable salt thereof; or an ester thereof. The invention also provides pharmaceutical compositions comprising compounds of formula (I), methods of preparing compounds of formula (I), and methods of treatment using compounds of formula (I).
FILED Friday, August 24, 2001
APPL NO 10/363424
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
544/280
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US 07109341 Horwitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Jerome P. Horwitz (Farmington Hills, Michigan);  Thomas H. Corbett (Grosse Pointe Park, Michigan);  Eduardo Palomino (Royal Oak, Michigan);  Lisa Polin (Oak Park, Michigan);  Stuart T. Hazeldine (Taylor, Michigan)
ABSTRACT The invention provides compounds of the formula:
wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.
FILED Thursday, July 03, 2003
APPL NO 10/613914
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Organic compounds
546/157
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US 07109343 Davies
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Huw M. L. Davies (Clarence Center, New York)
ABSTRACT Compounds having the formula:
are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessary to complete a 3–12 membered heterocyclic ring; Z1 is an alkylene or arylene group; Q1 and Q2 are the same or different and are electron withdrawing groups; L1 and L3, taken together, represent —O—CR13—O—; L2 and L4, taken together, represent —O—CR14—O—; and R13 and R14 are the same or different and are selected from the group consisting of alkyl groups and aryl groups or R13 and R14 represent alkylene or arylene groups that are directly or indirectly bonded to one another. Methods for making such compounds are also disclosed, as are intermediates which can be used in their preparation. Also disclosed are methods for carrying out C—H insertion reactions using bis-transition metal catalysts, such as the above compounds. Procedures for preparing d-threo methylphenidate, tolterodine, CDP-840, nominfensine, and sertraline, are described.
FILED Monday, April 05, 2004
APPL NO 10/817443
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
546/268.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109345 Ortiz-Marciales et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Margarita Ortiz-Marciales (Humacao, Puerto Rico);  Melvin de Jesús (Humacao, Puerto Rico);  Eduvigis Gonzalez (Humacao, Puerto Rico);  Sandraliz Espinosa (Humacao, Puerto Rico);  Wildeliz Correa-Ramirez (Humacao, Puerto Rico)
ABSTRACT A novel and efficient alkylation procedure of B—H-1,3,2-oxazaborolidines derived from ephedrine and norephedrine has been established. Representative B-butyl- and B-methyl-1,3,2-oxazaborolidines were prepared in good yield and excellent purity by one pot treatment of the parent boraheterocyclic compound with the corresponding organolithium reagent and subsequent hydrolysis of the cyclic borohydride with anhydrous ammonium chloride.
FILED Monday, February 09, 2004
APPL NO 10/775011
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/110
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US 07109377 Schreiber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Stuart L. Schreiber (Boston, Massachusetts);  Matthew D. Shair (Somerville, Massachusetts);  Derek S. Tan (Rochester, New York);  Michael A. Foley (Somerville, Massachusetts);  Brent R. Stockwell (Boston, Massachusetts)
ABSTRACT The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.
FILED Thursday, June 27, 2002
APPL NO 10/185364
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
564/191
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109380 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S)
ASSIGNEE(S) The University of Mississippi (University, Mississippi);  The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Xing-Cong Li (Oxford, Mississippi);  Melissa R. Jacob (Oxford, Mississippi);  David Wedge (Oxford, Mississippi)
ABSTRACT Compounds and methods useful in the control, treatment, and prevention of fungal activity, of the following formula:
where R1-3 are independently H, alkyl, methyl, acyl, halogen, phenyl, R4 is H, alkyl, methyl, acyl, alkoxy, halogen, phenyl provided that when R3 is methyl and R4 is H, R1 and R2 are not both H; and stereoisomers, analogs, and pharmaceutically acceptable salts thereof.
FILED Tuesday, March 29, 2005
APPL NO 11/093695
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
568/379
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US 07109479 Krutchinsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Andrew Krutchinsky (New York, New York);  Herbert Cohen (New York, New York);  Markus Kalkum (New York, New York);  Vadim Sherman (Brooklyn, New York);  Brian Chait (New York, New York)
ABSTRACT A system for determining the ratio of mass to charge of an ion including a pulsed ionizer, a high pressure co-linear ion guide/accelerator, and a mass analyzer. The pulsed ionizer generates intact analyte ions from a sample of matter to be analyzed. The high pressure co-linear ion guide/accelerator is interfaced with the ion source for receipt of the intact ions of the sample. The ion guide/accelerator simultaneously dampens and linearly accelerates the intact ions in the substantial absence of fragmentation of the ions to provide a substantially continuous beam of the intact ions for mass analysis. The mass analyzer is connected to the ion guide/accelerator for receipt of the beam of ions and determines the mass to charge ratio of the intact ions.
FILED Tuesday, September 28, 2004
APPL NO 10/952529
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/288
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National Science Foundation (NSF) 

US 07107842 Wu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Wei-Chung Wu (Albany, California);  Robert Wood (Berkeley, California)
ABSTRACT An angular rate sensing system suitable for a micromechanical flying insect (MFI) device. The system includes a rod, or haltere, that is moved in a plane by a piezoelectric actuator. Bending of the haltere due to angular movement of a body onto which the haltere is coupled is sensed with a resistive strain gage. In a first embodiment the haltere is actuated (i.e., made to beat or sweep) by simple coupling to an actuator. In a second embodiment, a four-bar structure is used to amplify the motion of a piezoelectric bender to cause haltere beating. Another embodiment achieves haltere beating by parasitic transmission of vibrations of the MFI body to the base of the haltere.
FILED Monday, May 03, 2004
APPL NO 10/838480
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/504.150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109001 Benfey et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Philip N. Benfey (Chapel Hill, North Carolina);  Gary Schindelman (Pasadena, California)
ABSTRACT A method by which many plants control organ shape is by regulated, differential cellular expansion. A gene involved in regulating the expansion of plants cells, such as Arabidopsis thaliana root cells is COBRA which encodes a protein with a putative GPI anchor. Plants comprising altered root morphologies may be produced by control of COBRA activity. For example, roots which lack COBRA activity comprise thicker, fatter roots (a CORE or cob phenotype) which are well suited for penetrating dense, compacted soil. Plants lacking COBRA activity may be useful in applications wherein plant growth in areas with dense soil would be beneficial. The present invention comprises the Arabidopsis thaliana COBRA gene and COBRA protein and homologues thereof as well as mutated alleles of COBRA. Also provided are anti-COBRA antibodies, transgenic plants which overexpress COBRA and methods for identifying COBRA modulating substances.
FILED Thursday, April 25, 2002
APPL NO 10/133985
ART UNIT 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109121 Lal et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Amit Lal (Ithaca, New York);  Max G. Lagally (Madison, Wisconsin);  Chung Hoon Lee (Ithaca, New York);  Paul Powell Rugheimer (Bozeman, Montana)
ABSTRACT A method of forming a suspended semiconductor film is provided comprising providing a semiconductor structure including a layer of semiconductor film over a sacrificial layer, the semiconductor film secured to a substrate; depositing a film of material over the semiconductor film that has a tensile or compressive strain with respect to the semiconductor film patterning the deposited film to leave opposed segments spaced from each other by a central portion of the semiconductor film; patterning the semiconductor film and removing the sacrificial layer beneath the semiconductor film to leave a semiconductor film section anchored to the substrate at at least two anchor positions, with the film segments remaining on the semiconductor film adjacent to the anchor positions and spaced from each other by the central position of the suspended semiconductor film such that the film segments apply a tensile or compressive stress to the suspended semiconductor film.
FILED Thursday, June 24, 2004
APPL NO 10/876140
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/703
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109343 Davies
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Huw M. L. Davies (Clarence Center, New York)
ABSTRACT Compounds having the formula:
are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessary to complete a 3–12 membered heterocyclic ring; Z1 is an alkylene or arylene group; Q1 and Q2 are the same or different and are electron withdrawing groups; L1 and L3, taken together, represent —O—CR13—O—; L2 and L4, taken together, represent —O—CR14—O—; and R13 and R14 are the same or different and are selected from the group consisting of alkyl groups and aryl groups or R13 and R14 represent alkylene or arylene groups that are directly or indirectly bonded to one another. Methods for making such compounds are also disclosed, as are intermediates which can be used in their preparation. Also disclosed are methods for carrying out C—H insertion reactions using bis-transition metal catalysts, such as the above compounds. Procedures for preparing d-threo methylphenidate, tolterodine, CDP-840, nominfensine, and sertraline, are described.
FILED Monday, April 05, 2004
APPL NO 10/817443
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
546/268.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109348 Nolan
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of New Orleans Research and Technology Foundation, Inc. (New Orleans, Louisiana)
INVENTOR(S) Steven P. Nolan (New Orleans, Louisiana)
ABSTRACT Imidazolium salts are the immediate precursors to N-heterocyclic carbenes (NHC) yet a simple, general synthetic route to a wide variety of imidazolium salts is not yet available. Such a straightforward route is described for two specific members of this family of ligand precursor: 1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride (IMes.HCl) and 1,3-Bis(2,6-diispropylphenyl)imidazolium chloride (IPr.HCl). The procedure appears general and similar protocols can be used to isolate various imidazolium salts.
FILED Tuesday, September 02, 2003
APPL NO 10/653688
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/335.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109397 Collmer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Alan Collmer (Ithaca, New York);  Adela Ramos (Ithaca, New York)
ABSTRACT The present invention relates to isolated DNA molecules that encode proteins or polypeptides which elicit a hypersensitive response in plants. One aspect of the present invention involves an isolated DNA molecule that encodes the HopPtoP protein of Pseudomonas syringae pv. tomato DC3000. The isolated DNA molecules can be used to impart disease resistance, stress resistance, and enhanced growth to plants or plants grown from treated seeds, to control insects on plants or plants grown from treated plant seeds, to impart post-harvest disease or desiccation resistance in fruits or vegetables, to impart enhanced longevity of fruit or vegetable ripeness, to impart desiccation resistance to cuttings of ornamental plants, and/or promote early flowering of ornamental plants, either by topical application of the proteins or polypeptides or transgenic expression in recombinant plants or plant seeds. Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are disclosed.
FILED Thursday, January 30, 2003
APPL NO 10/355956
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/301
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109473 Grier et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) University of Chicago (Chicago, Illinois)
INVENTOR(S) David G. Grier (Chicago, Illinois);  Jennifer E. Curtis (Chicago, Illinois)
ABSTRACT A method and system for generating modulated optical vortices. Optical vortices can be used for a variety of applications, such as applying controlled torque or controlled force patterns to objects from a few nanometers to hundreds of micrometers in size. Numerous optical modes of optical vortices can be created to meet virtually any desired need in manipulating of objects. Furthermore, one can modify the wavefront of a beam of light in a specific way to create a new type of optical trap useful for manipulating mesoscopic materials. When the modified beam is brought to a focus, the resulting optical trap exerts forces transverse to the optical axis that can be used to transport mesoscopic matter such as nanoclusters, colloidal particles, and biological cells.
FILED Wednesday, September 10, 2003
APPL NO 10/659153
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/251
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109698 Swenson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Atmospheric Sciences (ATM)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents, University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Jody A. Swenson (Hyde Park, Utah);  William H. Beasley (Norman, Oklahoma);  Leon G. Byerley (Tuscon, Arizona);  Ivan G. Bogoev (Hyde Park, Utah)
ABSTRACT An electric-field meter provided with a housing, an electrode assembly, a shield assembly, a movement assembly, a position detection assembly, a charge measurement circuit, and a leakage current compensation circuit. The electric-field meter can be characterized as a field mill, an induction voltmeter, an electrostatic fluxmeter or an agrimeter. The electrode assembly is selectively exposed to the electric field. The shield assembly alternately covers and exposes the electrode assembly to the electric field. The movement assembly has a source of motive force and a linkage operably connected to one of the shield assembly and the electrode assembly for alternately covering and exposing the electrode assembly to the electric field. The charge measurement circuit receives charge on the electrode assembly. The charge measurement circuit provides a charge detection signal indicative of the charge induced on the electrode assembly as the electrode assembly is selectively exposed to the electric field. A current compensation circuit is provided for offsetting an average leakage current at the input of the charge measurement circuit.
FILED Thursday, March 25, 2004
APPL NO 10/808648
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/72
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110118 Ünlü et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Selim M. Ünlü (Jamaica Plain, Massachusetts);  Anna Swan (Cambridge, Massachusetts);  Bennett B. Goldberg (Newton, Massachusetts);  Stephen Ippolito (Tampa, Florida);  Lev Moiseev (Brighton, Massachusetts);  Samuel Lipolf (Newton, Massachusetts);  Yunjie Tong (Allston, Massachusetts)
ABSTRACT A method and apparatus for performing optical microscopy in one to three dimensions employs a spectral self-interference fluorescent microscopy technique that includes providing at least one fluorescent microscopy sample, at least one objective lens, and at least one reflecting surface. The fluorescent sample is disposed between the objective lens and the reflecting surface, the distance from the sample to the reflecting surface being several to several tens times an excitation wavelength. Excitation light causes the fluorescent sample to emit light, at least a portion of which is reflected by the reflecting surface. The objective lens collects the reflected light and the light emitted directly by the fluorescent sample. The direct and reflected light interfere causing spectral oscillations in the emission spectrum. The periodicity and the peak wavelengths of the emission spectrum are spectroscopically analyzed to determine the optical path length between the fluorescent sample and the reflecting surface.
FILED Wednesday, December 19, 2001
APPL NO 10/451096
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110350 Li et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainsville, Florida)
INVENTOR(S) Jian Li (Gainesville, Florida);  Jianhua Liu (Gainesville, Florida)
ABSTRACT A system and method for enhancing the data rate of a WLAN. Through the deployment of a MIMO system, the data rate ordinarily expected of a SISO type system can be doubled. Yet, the MIMO system of the present invention can remain backward compatible with conventional WLAN standards implemented by typical SISO type system. In particular, the packet preamble of the MIMO packet of the present invention is similar to that of a conventional SISO system so as to be backward compatible with conventional SISO receivers. Additionally, the data model of the MIMO system can be configured to support the detection of symbols in the MIMO packet of the present invention. Importantly, the present invention can include a least squares soft-detector for use in a wireless LAN compatible MIMO system.
FILED Friday, March 05, 2004
APPL NO 10/793712
ART UNIT 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Multiplex communications
370/204
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110378 Onggosanusi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Eko Nugroho Onggosanusi (Dallas, Texas);  Barry Dean Van Veen (McFarland, Wisconsin);  Akbar Muhammad Sayeed (Madison, Wisconsin)
ABSTRACT A method and system is described for more optimally managing the usage of a wideband space-time multipath channel. The wideband space-time multipath channel is decomposed into a plurality of orthogonal sub-channels, where the orthogonal sub-channels having the best signaling characteristics are used for transmitting one or more signal streams. For purposes of decomposing the wideband space-time multipath channel into a plurality of orthogonal sub-channels, channel estimates are determined for each signal propagation path. A closed-form singular value decomposition of the channel corresponding to each receive antenna before coherent combining is utilized to obtain an orthogonal decomposition of the overall effective space-time channel after coherent combining. By using the overall effective space-time channel after coherent combining rather than before coherent combining, the complexity and correspondingly the resources required for obtaining the orthogonal sub-channels is significantly reduced. The method and system further provide for transmit power to be allocated between the selected sub-channels in order to minimize the effective bit-error rate for a fixed average throughput or to maximize average throughput for a fixed minimum effective bit-error rate.
FILED Wednesday, October 03, 2001
APPL NO 09/970460
ART UNIT 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Multiplex communications
370/334
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07111316 Zahorjan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John Zahorjan (Seattle, Washington);  Derek L. Eager (Saskatoon, Canada);  Mary K. Vernon (Madison, Wisconsin)
ABSTRACT Preferred techniques for transmitting on-demand data files include transmitting a first data stream in response to a first client request, and a new data stream in response to a subsequent second client request. The second client may snoop increasing amounts data from the first data stream, thereby decreasing the second client's reliance on the second data stream until the client has merged with the first data stream, at which time transmission of the second data stream will be discontinued. Alternatively, a patch data stream may be broadcast to the second client having a bandwidth less than that of the first data stream. The second client, in addition to receiving the second data stream real-time, will record data from a patch data stream until the second client has merged with the first data stream, at which time transmission of the second data stream and patch data stream will be discontinued.
FILED Monday, August 07, 2000
APPL NO 09/633507
ART UNIT 2623 — Selective Visual Display Systems
CURRENT CPC
Interactive video distribution systems
725/97
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07107851 Owen
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Southwest Research Institute (San Antonio, Texas)
INVENTOR(S) Thomas E. Owen (Helotes, Texas)
ABSTRACT A method, used in connection with a pulse-echo type sensor for determining the speed of sound in a gas, for improving the accuracy of speed of sound measurements. The sensor operates on the principle that speed of sound can be derived from the difference between the two-way travel time of signals reflected from two different target faces of the sensor. This time difference is derived by computing the cross correlation between the two reflections. The cross correlation function may be fitted to a parabola whose vertex represents the optimum time coordinate of the coherence peak, thereby providing an accurate measure of the two-way time diffference.
FILED Monday, July 19, 2004
APPL NO 10/894084
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/597
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109600 Bywaters et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Northern Power Systems, Inc. (Waitsfield, Vermont)
INVENTOR(S) Garrett Lee Bywaters (Waitsfield, Vermont);  William Danforth (Rochester, Vermont);  Christopher Bevington (Waitsfield, Vermont);  Jesse Stowell (Warren, Vermont);  Daniel Costin (Chelsea, Vermont)
ABSTRACT A wind turbine is provided that minimizes the size of the drive train and nacelle while maintaining the power electronics and transformer at the top of the tower. The turbine includes a direct drive generator having an integrated disk brake positioned radially inside the stator while minimizing the potential for contamination. The turbine further includes a means for mounting a transformer below the nacelle within the tower.
FILED Friday, May 19, 2006
APPL NO 11/419299
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Prime-mover dynamo plants
290/55
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109818 Rivkina et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Midwest Research Institute (Kansas City, Missouri)
INVENTOR(S) Tatiana Rivkina (Lakewood, Colorado);  David S. Ginley (Evergreen, Colorado)
ABSTRACT A tunable circuit (10) for a capacitively tunable capacitor device (12) is provided. The tunable circuit (10) comprises a tunable circuit element (14) and a non-tunable dielectric element (16) coupled to the tunable circuit element (16). A tunable capacitor device (12) and a method for increasing the figure of merit in a tunable capacitor device (12) are also provided.
FILED Friday, December 14, 2001
APPL NO 10/498457
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/24.C00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110171 Dane et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Metal Improvement Company, LLC (Paramus, New Jersey);  The United States of America as represented by the Department of Energy (Washington, District of Columbia)
INVENTOR(S) C. Brent Dane (Livermore, California);  Lloyd Hackel (Livermore, California);  Fritz B. Harris (Rocklin, California)
ABSTRACT A laser system includes an optical path having an intracavity relay telescope with a telescope focal point for imaging an output of the gain medium between an image location at or near the gain medium and an image location at or near an output coupler for the laser system. A kinematic mount is provided within a vacuum chamber, and adapted to secure beam baffles near the telescope focal point. An access port on the vacuum chamber is adapted for allowing insertion and removal of the beam baffles. A first baffle formed using an alignment pinhole aperture is used during alignment of the laser system. A second tapered baffle replaces the alignment aperture during operation and acts as a far-field baffle in which off angle beams strike the baffle a grazing angle of incidence, reducing fluence levels at the impact areas.
FILED Wednesday, January 28, 2004
APPL NO 10/766224
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optical: Systems and elements
359/347
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110174 Dane et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Metal Improvement Company, LLC (Paramus, New Jersey);  The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) C. Brent Dane (Livermore, California);  Lloyd Hackel (Livermore, California);  Fritz B. Harris (Rocklin, California)
ABSTRACT A laser system includes an optical path having an intracavity relay telescope with a telescope focal point for imaging an output of the gain medium between an image location at or near the gain medium and an image location at or near an output coupler for the laser system. A kinematic mount is provided within a vacuum chamber, and adapted to secure beam baffles near the telescope focal point. An access port on the vacuum chamber is adapted for allowing insertion and removal of the beam baffles. A first baffle formed using an alignment pinhole aperture is used during alignment of the laser system. A second tapered baffle replaces the alignment aperture during operation and acts as a far-field baffle in which off angle beams strike the baffle a grazing angle of incidence, reducing fluence levels at the impact areas.
FILED Thursday, November 10, 2005
APPL NO 11/271197
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optical: Systems and elements
359/423
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07108232 Hoh
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Roger H. Hoh (Lomita, California)
ABSTRACT A force-feel system is implemented by mechanically coupling a servo-actuator to and in parallel with a flight control system. The servo-actuator consists of an electric motor, a gearing device, and a clutch. A commanded cockpit-flight-controller position is achieved by pilot actuation of a trim-switch. The position of the cockpit-flight-controller is compared with the commanded position to form a first error which is processed by a shaping function to correlate the first error with a commanded force at the cockpit-flight-controller. The commanded force on the cockpit-flight-controller provides centering forces and improved control feel for the pilot. In an embodiment, the force-feel system is used as the basic element of stability augmentation system (SAS). The SAS provides a stabilization signal that is compared with the commanded position to form a second error signal. The first error is summed with the second error for processing by the shaping function.
FILED Thursday, February 05, 2004
APPL NO 10/772990
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/223
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07108934 Narayanan et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Instituite of Technology (Pasadena, California)
INVENTOR(S) Sekharipuram R. Narayanan (Arcadia, California);  Shiao-Pin S. Yen (Altadena, California)
ABSTRACT A “water free,” proton conducting membrane for use in a fuel cell is fabricated as a highly conducting sheet of converted solid state organic amine salt, such as converted acid salt of triethylenediamine with two quaternized tertiary nitrogen atoms, combined with a nanoparticulate oxide and a stable binder combined with the converted solid state organic amine salt to form a polymeric electrolyte membrane. In one embodiment the membrane is derived from triethylenediamine sulfate, hydrogen phosphate or trifiate, an oxoanion with at least one ionizable hydrogen, organic tertiary amine bisulfate, polymeric quaternized amine bisulfate or phosphate, or polymeric organic compounds with quaternizable nitrogen combined with Nafion to form an intimate network with ionic interactions.
FILED Friday, January 17, 2003
APPL NO 10/346812
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/33
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109287 Connell et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) John W. Connell (Yorktown, Virginia);  Joseph G. Smith, Jr. (Smithfield, Virginia);  Paul M. Hergenrother (Yorktown, Virginia);  Kent A. Watson (New Kent, Virginia);  Craig M. Thompson (Newport News, Virginia)
ABSTRACT Polyimides displaying low color in thin films, atomic oxygen resistance, vacuum ultraviolet radiation resistance, solubility in organic solvents in the imide form, high glass transition (Tg) temperatures, and high thermal stability are provided. The poly(amide acid)s, copoly(amide acid)s, polyimides and copolyimides are prepared by the reaction of stoichiometric ratios of an aromatic dianhydride with diamines which contain phenylphosphine oxide groups in polar aprotic solvents. Controlled molecular weight oligomeric (amide acid)s and imides can be prepared by offsetting the stoichiometry according to the Carothers equation using excess diamine and endcapping with aromatic anhydrides. The polyimide materials can be processed into various material forms such as thin films, fibers, foams, threads, adhesive film, coatings, dry powders, and fiber coated prepreg, and uses include thin film membranes on antennas, second-surface mirrors, thermal optical coatings, and multi-layer thermal insulation (MLI) blanket materials.
FILED Monday, November 08, 2004
APPL NO 10/988407
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
528/337
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110118 Ünlü et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Selim M. Ünlü (Jamaica Plain, Massachusetts);  Anna Swan (Cambridge, Massachusetts);  Bennett B. Goldberg (Newton, Massachusetts);  Stephen Ippolito (Tampa, Florida);  Lev Moiseev (Brighton, Massachusetts);  Samuel Lipolf (Newton, Massachusetts);  Yunjie Tong (Allston, Massachusetts)
ABSTRACT A method and apparatus for performing optical microscopy in one to three dimensions employs a spectral self-interference fluorescent microscopy technique that includes providing at least one fluorescent microscopy sample, at least one objective lens, and at least one reflecting surface. The fluorescent sample is disposed between the objective lens and the reflecting surface, the distance from the sample to the reflecting surface being several to several tens times an excitation wavelength. Excitation light causes the fluorescent sample to emit light, at least a portion of which is reflected by the reflecting surface. The objective lens collects the reflected light and the light emitted directly by the fluorescent sample. The direct and reflected light interfere causing spectral oscillations in the emission spectrum. The periodicity and the peak wavelengths of the emission spectrum are spectroscopically analyzed to determine the optical path length between the fluorescent sample and the reflecting surface.
FILED Wednesday, December 19, 2001
APPL NO 10/451096
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110915 Wilson
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Edward Wilson (Redwood City, California)
ABSTRACT The present invention is a method for identifying unknown parameters in a system having a set of governing equations describing its behavior that cannot be put into regression form with the unknown parameters linearly represented. In this method, the vector of unknown parameters is segmented into a plurality of groups where each individual group of unknown parameters may be isolated linearly by manipulation of said equations. Multiple concurrent and independent recursive least squares identification of each said group run, treating other unknown parameters appearing in their regression equation as if they were known perfectly, with said values provided by recursive least squares estimation from the other groups, thereby enabling the use of fast, compact, efficient linear algorithms to solve problems that would otherwise require nonlinear solution approaches. This invention is presented with application to identification of mass and thruster properties for a thruster-controlled spacecraft.
FILED Thursday, May 06, 2004
APPL NO 10/841117
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/181
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07109380 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S)
ASSIGNEE(S) The University of Mississippi (University, Mississippi);  The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Xing-Cong Li (Oxford, Mississippi);  Melissa R. Jacob (Oxford, Mississippi);  David Wedge (Oxford, Mississippi)
ABSTRACT Compounds and methods useful in the control, treatment, and prevention of fungal activity, of the following formula:
where R1-3 are independently H, alkyl, methyl, acyl, halogen, phenyl, R4 is H, alkyl, methyl, acyl, alkoxy, halogen, phenyl provided that when R3 is methyl and R4 is H, R1 and R2 are not both H; and stereoisomers, analogs, and pharmaceutically acceptable salts thereof.
FILED Tuesday, March 29, 2005
APPL NO 11/093695
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
568/379
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109394 Fischer et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of California (Oakland, California)
INVENTOR(S) Robert Fischer (El Cerrito, California);  Yeonhee Choi (Emeryville, California);  Mike Hannon (Livermore, California)
ABSTRACT This invention is directed to plant genetic engineering. In particular, it relates to DEMETER (DMT) nucleic acids and polypeptides that control, for example, seed (and in particular endosperm, embryo and seed coat) development, flowering time, chromosomal DNA methylation and transcription in plants.
FILED Monday, April 23, 2001
APPL NO 09/840743
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/290
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110118 Ünlü et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Selim M. Ünlü (Jamaica Plain, Massachusetts);  Anna Swan (Cambridge, Massachusetts);  Bennett B. Goldberg (Newton, Massachusetts);  Stephen Ippolito (Tampa, Florida);  Lev Moiseev (Brighton, Massachusetts);  Samuel Lipolf (Newton, Massachusetts);  Yunjie Tong (Allston, Massachusetts)
ABSTRACT A method and apparatus for performing optical microscopy in one to three dimensions employs a spectral self-interference fluorescent microscopy technique that includes providing at least one fluorescent microscopy sample, at least one objective lens, and at least one reflecting surface. The fluorescent sample is disposed between the objective lens and the reflecting surface, the distance from the sample to the reflecting surface being several to several tens times an excitation wavelength. Excitation light causes the fluorescent sample to emit light, at least a portion of which is reflected by the reflecting surface. The objective lens collects the reflected light and the light emitted directly by the fluorescent sample. The direct and reflected light interfere causing spectral oscillations in the emission spectrum. The periodicity and the peak wavelengths of the emission spectrum are spectroscopically analyzed to determine the optical path length between the fluorescent sample and the reflecting surface.
FILED Wednesday, December 19, 2001
APPL NO 10/451096
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07109249 Bruza et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Dow Global Technologies Inc. (Midland, Michigan)
INVENTOR(S) Kenneth J. Bruza (Alma, Michigan);  James P. Godschalx (Midland, Michigan);  Edward O. Shaffer, II (Midland, Michigan);  Dennis W. Smith, Jr. (Seneca, South Carolina);  Paul H. Townsend, III (Midland, Michigan);  Kevin J. Bouck (Midland, Michigan);  Qing Shan J. Niu (Midland, Michigan)
ABSTRACT A suitable cross-linkable matrix precursor and a poragen can be treated to form a porous cross-linked matrix having a Tg of greater than 300° C. The porous matrix material has a lower dielectric constant than the corresponding non-porous matrix material, making the porous matrix material particularly attractive for a variety of electronic applications including integrated circuits, multichip modules, and flat panel display devices.
FILED Friday, July 16, 2004
APPL NO 10/893640
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
521/77
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07109300 Losso et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S)
ASSIGNEE(S) Board of Supervisors of Louisiana State Univeristy And Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Jack N. Losso (Baton Rouge, Louisiana);  Masahiro Ogawa (Kagawa, Japan);  Ralph J. Portier (Baton Rouge, Louisiana);  Mark A. Schexnayder (Metairie, Louisiana)
ABSTRACT A method is disclosed for extracting collagen from calcified tissue without a prior decalcification step. The method may be used with calcified tissues such as fish skin with scales, alligator skeletons, and crustacean exoskeletons. It does not require the use of EDTA. When fish skin is used that contains substantial quantities of scales, it is not necessary first to remove scales from the skin before conducting the extraction of collagen.
FILED Monday, April 18, 2005
APPL NO 11/108594
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/356
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 07108975 Fink et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) John K. Fink (Ann Arbor, Michigan);  Xinping Zhao (Houston, Texas)
ABSTRACT The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
FILED Thursday, September 12, 2002
APPL NO 10/242008
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07108016 Moskalik et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the Environmental Protection Agency (Washington, District of Columbia)
INVENTOR(S) Andrew J. Moskalik (Detroit, Michigan);  Charles L. Gray, Jr. (Pinckney, Michigan)
ABSTRACT A lightweight, low permeation, piston-in-sleeve high pressure accumulator is provided. The accumulator includes a cylindrical composite pressure vessel with two integral rounded ends. A piston slidably disposed in a thin nonpermeable internal sleeve in the accumulator separates two chambers, one adapted for containing a working fluid and the other adapted for containing gas under pressure. Working fluid is provided in a volume between the nonpermeable internal sleeve and the composite pressure vessel wall. Further means are provided for withstanding harmful effects of radial flexing of the composite vessel wall under high pressures, and from stresses present in use in mobile applications such as with a hydraulic power system for a hydraulic hybrid motor vehicle. A method for pre-charging the device is also presented.
FILED Monday, March 07, 2005
APPL NO 11/074147
ART UNIT 3754 — Fluid Handling and Dispensing
CURRENT CPC
Pipes and tubular conduits
138/31
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 07109041 Sklar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Non-Profit Organization (NPO)
American Heart Association (AHA)
APPLICANT(S)
ASSIGNEE(S) Science and Technology Corporation @University of New Mexico (Albuquerque, New Mexico)
INVENTOR(S) Larry Sklar (Albuquerque, New Mexico);  Eric Prossnitz (Albuquerque, New Mexico);  Vilven Janeen (Albuquerque, New Mexico);  Donna Neldon (Los Lunas, New Mexico)
ABSTRACT A display and method of preparing 7-transmembrane and other receptors for real-time kinetic analysis of binding interactions. The invention includes display on beads and in micelles for multi-well and flow cytometric analysis. The invention is useful for ligand discovery and drug action discovery, and G-protein response in particular.
FILED Thursday, March 21, 2002
APPL NO 10/101870
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/501
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07108769 Constantz
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Interior (Washington, District of Columbia)
INVENTOR(S) James Edward Constantz (Portola Valley, California)
ABSTRACT A solar distillation loop apparatus includes a first pipe section disposed on a ground surface, the first pipe section including a substantially straight portion and elevated portions on each end of the substantially straight portion, an impure water inflow coupling at one end of the straight portion and an impure water outflow coupling at the other end of the straight portion; solar powered fans disposed in each of the elevated portions of the first pipe section; a second pipe section disposed under the ground surface beneath the first pipe section; and two substantially vertical pipe sections that connect respective ends of the second pipe section to respective ends of the first pipe section.
FILED Wednesday, December 03, 2003
APPL NO 10/729265
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Distillation: Processes, separatory
23/10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07110013 Ebersole et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Information Decision Technology (Bedford, New Hampshire)
INVENTOR(S) John Franklin Ebersole (Bedford, New Hampshire);  John Franklin Ebersole, Jr. (Bedford, New Hampshire);  Todd Joseph Furlong (Goffstown, New Hampshire)
ABSTRACT A system for creating an augmented reality display coupled with a firefighter's self-contained breathing apparatus (SCBA) mask. The invention combines a camera, motion tracking sensor, head-mounted display, SCBA mask, and optional head phones into a display suitable for performing exercises, such as training of firefighters or other emergency first responders, in augmented reality.
FILED Thursday, August 09, 2001
APPL NO 09/927043
ART UNIT 2629 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Recorders
346/8
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, September 19, 2006.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060919.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital