FedInvent™ Patents

Patent Details for Tuesday, October 17, 2006 

This page was updated on Sunday, March 26, 2023 at 08:05 PM GMT

Department of Health and Human Services (HHS) 

US 07122033 Wood
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Bradford J. Wood (Chevy Chase, Maryland)
ABSTRACT Disclosed are methods and devices for occluding the lumen of a hollow organ by delivering radiofrequency energy to the inner wall of a hollow organ. The disclosure includes radiofrequency electrodes that expand, in a deployed condition, to contact the walls of the organ. In some embodiments, the electrodes substantially conform to the inner wall to enhance therapeutic contact. Methods are also disclosed for using these electrodes to totally or partially occlude a lumen, or remove or reduce a total or partial occlusion of a lumen.
FILED Wednesday, December 10, 2003
APPL NO 10/733225
ART UNIT 3739 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Surgery
66/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122179 Kappe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Seattle Biomedical Research Institute (Seattle, Washington);  Ruprecht-Karls-Universität Heidelberg (Heidelberg, Germany)
INVENTOR(S) Stefan H. I. Kappe (Seattle, Washington);  Kai-Uwe C. Matuschewski (Heidelberg, Germany);  Ann-Kristin Mueller (Dossenheim, Germany)
ABSTRACT Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a gene whose expression is up-regulated in liver stage parasites and whose function is not required for entry into hose hepatocytes.
FILED Friday, March 11, 2005
APPL NO 11/078200
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.100
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US 07122180 Aldovini
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Anna Aldovini (Weston, Massachusetts)
ABSTRACT The present invention pertains to mutated, non-infectious HIV viral particles, vectors for production of such particles and vaccines employing such vectors. The non-infectious particles are obtained by introducing a number of inactivating mutations into a native viral genome. These mutations are designed so as to minimize the probability of genetic reversion to an infectious virus, while retaining the basic protein content and immunogenic properties of a wild-type virion. The altered viral genome expresses proteins that can assemble into non-infectious particles which contain immunogenic components of the virus, but which are unable to infect cells. The preferred mutations are introduced in at least one amino acid position of the nucleocapsid (NC) protein in combination with at least one other mutation in an amino acid position of the reverse transcriptase (RT) protein or the In protein. In one embodiment, the mutations to the native HIV genome may also be made in at least one amino acid position of the NC protein, at least one position in the RT protein, and at least one position in the integrase (In) protein. In another embodiment, the mutations to the native HIV genome may be introduced in clusters, where two or more mutations are made in the NC protein, the RT protein, the In protein, or any combinations thereof.
FILED Tuesday, October 23, 2001
APPL NO 10/000511
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122190 Bolognesi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Dani Paul Bolognesi (Durham, North Carolina);  Thomas James Matthews (Durham, North Carolina);  Carl T. Wild (Durham, North Carolina);  Shawn O'Lin Barney (Cary, North Carolina);  Dennis Michael Lambert (Cary, North Carolina);  Stephen Robert Petteway (Cary, North Carolina);  Alphonse J. Langlois (Durham, North Carolina)
ABSTRACT The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.
FILED Wednesday, October 09, 2002
APPL NO 10/267748
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/188.100
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US 07122200 Kropp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Bradley P. Kropp (Edmond, Oklahoma);  Earl Y. Cheng (Edmond, Oklahoma);  Yuan Yuan Zhang (Edmond, Oklahoma);  Rick Cowan (Oklahoma City, Oklahoma);  Peter Moore (Perry, Oklahoma)
ABSTRACT A method for providing a urinary tract tissue graft composition includes providing a tissue culture frame and a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in the tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. Smooth muscle and urothelial cells are isolated from a tissue specimen of a subject and cultured, and then seeded upon the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. A tissue culture frame in which such a urinary tract tissue graft may be formed is also disclosed.
FILED Monday, December 10, 2001
APPL NO 10/013270
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/423
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US 07122307 Rosen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York);  Research Foundation of State University of New York (Stony Brook, New York)
INVENTOR(S) Michael R. Rosen (New York, New York);  Richard B. Robinson (Cresskill, New Jersey);  Ira S. Cohen (Stony Brook, New York);  Han-Gang Yu (Stony Brook, New York)
ABSTRACT This invention provides for a chamber and system designed for use in assaying drug effects on heart rate. The chamber consists of a series of wells. Cardiac myocytes disaggregated from neonatal animals are plated onto the bottom of each well and grown under standard tissue culture conditions. When drugs are to be assayed, the cells in each well are loaded with a calcium sensitive dye and the beating rate in each is monitored with a photodiode. A drug is added in graded concentrations to each well, and equilibrated and effects on rate are observed. This construct permits use of a cell based bioassay for the study of drugs or agents that may alter cardiac rate. This invention can be used in high throughput screening of drugs to evaluate/predict their effects on cardiac rate and rhythm.
FILED Tuesday, July 03, 2001
APPL NO 09/898417
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07122322 Timms
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Kathy L. Timms (Columbia, Missouri)
ABSTRACT A method and kit of diagnosing endometriosis in a female patient suspected of having endometriosis. The method includes obtaining a sample from the patient. The sample is analyzed to detect the presence of a purified and isolated endometriotic haptoglobin designated ENDO-I and functional analogs thereof. A therapeutic for treating endometriosis by modulating the expression of a purified and isolated endometriotic haptoglobin designated ENDO-I and functional analogs thereof and a pharmaceutically acceptable carrier.
FILED Wednesday, November 27, 2002
APPL NO 10/306903
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122324 Ginsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Mark H. Ginsberg (San Diego, California);  Andrew L. Frelinger, III (North Reading, Massachusetts);  Edward F. Plow (San Diego, California)
ABSTRACT Diagnostic systems, methods, polypeptides and antibodies for detecting the presence of C-terminal hGPIIb fragment of the platelet receptor GPIIb-IIIa in a body fluid sample are disclosed.
FILED Friday, September 03, 2004
APPL NO 10/934774
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122328 Kingsley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) David Mark Kingsley (Stanford, California);  Michelle Deanetta Johnson (Tubingen, Germany);  Andrew Manlap Ho (Lexington, Massachusetts)
ABSTRACT The present invention features a novel human protein (ANK), nucleotide sequences encoding human ANK, and assays for ANK activity, including assays to identify therapeutics and diagnostic assays, e.g., for susceptibility to diseases such as arthritis. In related aspects the invention features expression vectors and host cells comprising polynucleotides that encode a human ANK. The present invention also relates to antibodies that bind specifically to a human ANK, and methods for producing human ANK polypeptides.
FILED Friday, January 05, 2001
APPL NO 10/169596
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
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US 07122335 Engelhardt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) John F. Engelhardt (Iowa City, Iowa);  Dongsheng Duan (Iowa City, Iowa)
ABSTRACT Agents and methods to alter rAAV transduction, including agents and methods to enhance rAAV transduction, are provided. For instance, the invention provides methods to identify agents that enhance AAV transduction after viral binding to the cell membrane and before second strand synthesis.
FILED Thursday, October 12, 2000
APPL NO 09/689136
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/29
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US 07122336 Das
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Kiron M. Das (Basking Ridge, New Jersey)
ABSTRACT This invention relates to the field of therapy and diagnostic methods for ulcerative colitis. Specifically, the method comprises administering a compound or recombinant protein that inhibits interaction between CEP and human tropomyosin. Also included in the invention are methods to screen for drugs useful in treating ulcerative colitis and diagnostic methods for detecting diseases associated with an autoantigen response to hTM in affected tissue.
FILED Wednesday, February 05, 2003
APPL NO 10/359401
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/29
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US 07122342 Xu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) ZymoGenetics, Inc. (Seattle, Washington);  University of Washington (Seattle, Washington)
INVENTOR(S) Wen-feng Xu (Mukilteo, Washington);  Scott R. Presnell (Seattle, Washington);  David P. Yee (Seattle, Washington);  Donald C. Foster (Seattle, Washington)
ABSTRACT The present invention relates to polynucleotide and polypeptide molecules for PAR4, a novel member of the protease-activated receptor family. The polypeptides, and polynucleotides encoding them, mediate biological responses and/or cellular signaling in response to proteases. Protease cleavage of PAR4 exposes a PAR4 extracellular amino terminal portion that serves as a ligand for the PAR4 receptor. PAR4 may be used as a target in drug screening, and further used to identify proteinaceous or non-proteinaceous PAR4 agonists and antagonists. The present invention also includes antibodies to the PAR4 polypeptides.
FILED Tuesday, August 10, 1999
APPL NO 09/371333
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122343 Petrini et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John H. J. Petrini (Madison, Wisconsin);  William Francis Morgan (Mill Valley, California);  Richard Scott Maser (Madison, Wisconsin);  James Patrick Carney (El Cerrito, California)
ABSTRACT An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.
FILED Wednesday, April 18, 2001
APPL NO 09/837138
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122348 Wong, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Kamehameha Kay-Min Wong, Jr. (Sierra Madre, California);  Saswati Chatterjee (Sierra Madre, California);  Joel Conrad (Claremont, California);  Stella Kim (San Diego, California)
ABSTRACT This invention pertains to methods for promoting stable and site-specific integration of rep deleted recombinant adeno-associated virus vectors which result in less variable transgene expression and increased safety. These vectors are useful for delivery of a functional gene product to the desired intracellular location.
FILED Thursday, December 11, 2003
APPL NO 10/732813
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122353 Shen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Ben Shen (Verona, Wisconsin)
ABSTRACT The present invention provides for fusion proteins that act as targeted drug carries. The proteins are derived from molecules that possess natural drug-binding capabilities that are further engineered to target specific cell types, and optionally to have altered/improved drug binding characteristics. These fusion proteins are useful in, for example, delivery of chemotherapeutic compounds to cancer cells.
FILED Thursday, August 05, 2004
APPL NO 10/912764
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122517 Hudson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Kansas University Medical Center (Kansas City, Kansas)
INVENTOR(S) Billy G. Hudson (Nashville, Tennessee);  Munirathinam Sundaramoorthy (Nashville, Tennessee)
ABSTRACT The present invention provides a crystallized NC1 domain hexamer of Type IV collagen, and methods for making the crystal, wherein the NC1 domain hexamer is crystallized such that the three dimensional structure of the crystallized NC1 domain hexamer can be determined to a resolution of at least 3 Å or better. The present invention also provides a method for designing compounds to inhibit angiogenesis, tumor growth, tumor metastasis, endothelial cell adhesion and/or proliferation, and/or basal lamina assembly, comprising analyzing the three dimensional structure of a crystallized Type IV collagen NC1 domain hexamer produced by the methods of the invention, and identifying and synthesizing compounds that target regions of the NC1 domain that have been identified by the analysis as being important for type IV collagen heterotrimer and hexamer assembly. The present invention also provides novel polypeptides designed by the rational drug design methods of the present invention, based on an analysis of the type TV collagen NC1 hexamer structure disclosed herein.
FILED Friday, July 26, 2002
APPL NO 10/206699
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122519 Joullié et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Madeleine M. Joullié (Philadelphia, Pennsylvania);  Bo Liang (Glenolden, Pennsylvania)
ABSTRACT The present invention relates to macrocyclic depsipeptides, including didemnin analogs and fragments thereof, which are useful as anti-cancer agents and for other purposes. The invention includes numerous didemnin analogs and fragments and methods of making them. Methods of using these compounds as inhibitors of protein synthesis, cell growth, and tumorigenesis and as enhancers of apoptosis are also provided.
FILED Friday, October 25, 2002
APPL NO 10/280584
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/10
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US 07122521 Raines et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Ronald T. Raines (Madison, Wisconsin);  Jonathan A. Hodges (Madison, Wisconsin)
ABSTRACT A novel collagen mimic comprising a tripeptide unit having the formula (flpYaaGly)n, where flp is 4(S)-fluoro-L-proline, is disclosed. The collagen mimic has increased stability relative to the collagen-related triple helices (ProYaaGly)n, (hypYaaGly)n, and (HypYaaGly)n.
FILED Wednesday, June 23, 2004
APPL NO 10/874725
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122522 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) CLF Medical Technology Acceleration Program, Inc. (Clifton Park, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  James A. Bennett (Delmar, New York);  Herbert I. Jacobson (Albany, New York);  Fassil B. Mesfin (Albany, New York)
ABSTRACT Therapeutic compounds which are cell proliferation modulators, preferably inhibitors. These modulators contain amino acid structures that are arranged as a hydrophilic analog of an alpha-fetoprotein. The modulator may be a peptide itself, e.g., an octapeptide like that of SEQ ID NO: 5; a peptidomimetic; or may be in the form of a pharmaceutically acceptable scaffold, such as a polycyclic hydrocarbon to which is attached the necessary amino acid structures for biological and/or chemical activity. The modulators of the invention are distinguished in one aspect over previous compounds in that they are orally active, and therefore do not have to be injected into the patient. The compositions and methods are useful for reducing estrogen-stimulated growth of cells, and treating or preventing cancer, such as breast cancer. The treatment or prevention methods can include the use of tamoxifen therapy in combination with the peptide therapy.
FILED Wednesday, November 20, 2002
APPL NO 10/300530
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/15
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US 07122529 Ruane et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Patrick H. Ruane (Baltimore, Maryland);  John P. Toscano (Baltimore, Maryland)
ABSTRACT Chemical compounds which release nitric oxide in a controlled manner upon photolysis with light are provided. These compounds are O2-benzyl, O2-naphthylmethyl and O2-naphthylallyl substituted diazeniumdiolates. Also provided are methods of preparing these novel compounds in high chemical yields as well as methods of using these compounds.
FILED Friday, July 12, 2002
APPL NO 10/483323
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/149
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US 07122533 Cushman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Mark S. Cushman (West Lafayette, Indiana);  O. M. Zack Howard (Frederick, Maryland)
ABSTRACT The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cosalane or an analog thereof. The invention further relates to methods, compounds and compositions for treating inflammatory diseases. In one form, a method includes administering to a patient a therapeutically effective amount of cosalane or an analog thereof.
FILED Tuesday, May 13, 2003
APPL NO 10/436845
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/169
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US 07122541 Wands et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S)
ASSIGNEE(S) Rhode Island Hospital (Providence, Rhode Island)
INVENTOR(S) Jack R. Wands (Waban, Massachusetts);  Rolf I. Carlson (Boston, Massachusetts);  Paul Maggio (Cranston, Rhode Island)
ABSTRACT The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue with Taurolidine.
FILED Monday, June 21, 2004
APPL NO 10/873802
ART UNIT 1614 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/222.500
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US 07122549 Myers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Andrew G. Myers (Boston, Massachusetts);  Alleyn T. Plowright (Manchester, United Kingdom)
ABSTRACT In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. In another aspect, the present invention provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. In yet another aspect, the present invention provides methods for treating cancer comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof.
FILED Friday, April 16, 2004
APPL NO 10/826859
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/250
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US 07122563 Struck
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Southern Research Institute (Birmingham, Alabama)
INVENTOR(S) Robert F. Struck (Birmingham, Alabama)
ABSTRACT Thiocarbonate and thiocarbamate derivatives of 4-demethylpenclomedine are provided along with pharmaceutical compositions containing them and use for treating cancer. A method for preparing the derivatives is also provided.
FILED Tuesday, February 01, 2005
APPL NO 11/046692
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/348
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US 07122572 Gale et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, University of Texas System (Austin, Texas)
INVENTOR(S) Philip A. Gale (Austin, Texas);  Jonathan L. Sessler (Austin, Texas);  Vladimír A. Král (Praha, Czech Republic);  Andrei Andrievsky (Rochester, New York);  Vincent Lynch (Austin, Texas);  Petra I. Sansom (Edgewater, New Jersey);  William E. Allen (Austin, Texas);  Christopher T. Brown (Austin, Texas);  Andreas Gebauer (Austin, Texas)
ABSTRACT The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.
FILED Friday, April 20, 2001
APPL NO 09/838998
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/427
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US 07122624 Usdin et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ted B. Usdin (Betheseda, Maryland);  Samuel R. J. Hoare (San Diego, California)
ABSTRACT An isolated or purified PTH2 receptor ligand or PTH1 receptor ligand is disclosed.
FILED Tuesday, December 11, 2001
APPL NO 10/014162
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/324
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122634 Lollar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) John S. Lollar (Decatur, Georgia)
ABSTRACT Specific amino acid loci of human factor VIII interact with inhibitory antibodies of hemophilia patients who have developed such antibodies after being treated with factor VIII. Modified factor VIII is disclosed in which the amino acid sequence is changed by a substitution at one or more of the specific loci. The modified factor VIII is not inhibited by inhibitory antibodies against the A2 or C2 domain epitopes. The modified factor VIII is useful for hemophiliacs, either to avoid or prevent the action of inhibitory antibodies.
FILED Friday, September 10, 2004
APPL NO 10/938414
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/383
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US 07122635 Brooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Peter C. Brooks (Hollywood, California);  Jingsong Xu (Alhambra, California);  Eric Petitclerc (Quebec, Canada)
ABSTRACT The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured collagen but not to native triple helical forms of the collagen. Antagonists of the invention can target, for example, denatured collagens type-I, type-II, type-III, type-IV, type-V and combinations thereof. Methods utilizing such antagonists for therapeutic treatment of tumor growth, tumor metastasis or of restenosis also are described, as are methods to use such antagonists as diagnostic markers of angiogenesis in normal or diseased tissues both in vivo and ex vivo. Antagonists include monoclonal antibodies referred to as HUI77, HUIV26, and XL313.
FILED Thursday, January 06, 2000
APPL NO 09/478977
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122650 Roseboom et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Patrick H. Roseboom (Madison, Wisconsin);  Ned H. Kalin (Madison, Wisconsin);  Steven A. Nanda (Madison, Wisconsin)
ABSTRACT Various human corticotropin-releasing factor binding protein promoter sequences are disclosed. Nucleic acids and host cells that contain the promoter sequences are also disclosed. Further disclosed are various methods involving the use of these sequences.
FILED Wednesday, October 01, 2003
APPL NO 10/676526
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.400
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US 07122686 Curran et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh (Pittsburgh, Pennsylvania)
INVENTOR(S) Dennis P. Curran (Pittsburgh, Pennsylvania);  Youseung Shin (Pittsburgh, Pennsylvania);  Nakyen Choy (Belle Mead, New Jersey);  Billy W. Day (Pittsburgh, Pennsylvania);  Raghavan Balachandran (Wexford, Pennsylvania);  Charitha Madiraju (Pittsburgh, Pennsylvania);  Tiffany Turner (Pittsburgh, Pennsylvania)
ABSTRACT A compound of the following structure:
wherein R1 is H, an alkyl group, an aryl group, an alkenyl group, an alkynyl group, or a halogen atom; R2 is H, an alkyl group, an aryl group, a benzyl group, a trityl group, —SiRaRbRc, CH2ORd, or CORe; Ra, Rb and Rc are independently an alkyl group or an aryl group; Rd is an alkyl group, an aryl group, an alkoxylalkyl group, —RiSiRaRbRc or a benzyl group, wherein Ri is an alkylene group; Re is an alkyl group, an allyl group, a benzyl group, an aryl group, an alkoxy group, or —NRgRh, wherein Rg and Rh are independently H, an alkyl group or an aryl group; R3 is (CH2)n where n is and integer in the range of 0 to 5, —CH2CH(CH3)—, —CH═CH—, —CH═C(CH3)—, or —C≡C—; R4 is (CH2)p where p is an integer in the range of 4 to 12, —(CHRk1)y1(CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5C(Rs1)═C(Rs2)C(Rs3)═C(Rs4)—, —(CHRk1)y1(CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5CH(Rs1) CH(Rs2)C(Rs3)═C(Rs4)—, —(CHRk1)y1(CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5C(Rs1)═C(Rs2)CH(Rs3)CH(Rs4)—, —(CHRk1)y1(CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5CH(Rs1) CH(Rs2)CH(Rs3)CH(Rs4)—, wherein y1 and y2 are 1 and y3, y4 and y5 are independently 0 or 1, Rk1, Rk2, Rk3, Rk4 and Rk5 are independently H, CH3, or OR2a, and Rs1, Rs2, Rs3, and Rs4 are independently H or CH3, wherein R2a is H, an alkyl group, an aryl group, a benzyl group, a trityl group, —SiRaRbRc, CH2ORd, or CORe; and R5 is H or OR2b, wherein R2b is H, an alkyl group, an aryl group, an aryl group, a benzyl group, a trityl group, —SiRaRbRc, CH2ORd, or CORe; provided that the compound is not dictyostatin 1.
FILED Friday, September 05, 2003
APPL NO 10/655916
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/266
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US 07122703 Saxon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Eliana Saxon (Albany, California);  Carolyn Bertozzi (Berkeley, California)
ABSTRACT The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
FILED Thursday, March 06, 2003
APPL NO 10/384099
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
568/17
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US 07122714 Sawyers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Charles L. Sawyers (Los Angeles, California);  Karen A. Klein (Los Angeles, California);  Owen N. Witte (Sherman Oaks, California);  Robert E. Reiter (Los Angeles, California)
ABSTRACT The present invention provides an immune deficient mouse having a human prostate xenograft of locally advanced or metastatic prostate cancer and uses thereof.
FILED Monday, February 04, 2002
APPL NO 10/067705
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/10
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US 07122823 Zeman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Social, Behavioral and Economic Sciences (SBE)
Division of Behavioral and Cognitive Sciences (BCS)
APPLICANT(S)
ASSIGNEE(S) The University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Herbert D. Zeman (Memphis, Tennessee)
ABSTRACT A radiation imaging apparatus includes a photostimulable phosphor plate, an x-ray source, a red or infrared laser, and an array of photomultiplier tubes. The x-ray source propagates x-rays toward the plate, which is incident on the plate at a first incidence angle. The x-rays interact with the plate to form a latent image therein. The laser propagates laser radiation toward the plate which is incident on the plate at a second incidence angle. According to the invention, the second incidence angle is equivalent to the first incidence angle at substantially all points on the plate. Based on the interaction of the laser radiation with the latent image in the plate, the plate emits visible image radiation. Thus, the x-ray radiation, which forms the image in the plate, follows the same path within the plate as does the laser radiation. By ensuring that the laser radiation follows the same path through the plate as the x-ray radiation, the invention achieves high spatial resolution in the image detected by the laser. The array of photomultiplier tubes receives the image radiation emitted by the plate and generates an electrical image signal based thereon. Based on this electrical image signal, the image formed in the plate may be displayed on a display device or printed on a printer. The device may also include an aspheric lens attached to the plate that refracts the laser radiation so that it enters the plate at the same incidence angle as the x-ray radiation. Using this lens, the x-ray and laser radiation may enter the plate from opposite sides of the plate and still follow the same path through the plate. Preferably, the photostimulable phosphor plate is formed of barium fluoroiodide—BaFI(Eu).
FILED Tuesday, February 08, 2005
APPL NO 11/053246
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/585
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US 07123351 Schaefer
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Philip R. Schaefer (Weaverville, North Carolina)
ABSTRACT A method and device for measuring a distance to an object with light determines the distance by measuring the relative intensity of light reflected from the object and traveling over two or more paths of differing optical length or reflected from the object and traveling over two or more paths through the use of the offset angle effect. Light is emitted by one or more light sources; reflected from a surface of the object; and the reflected light is detected by one or more light detectors. The light detector(s) generate signals based on the intensity of reflected light detected and the signals are utilized to calculate the distance from the device to the object.
FILED Thursday, November 03, 2005
APPL NO 11/267234
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/4.70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123762 Giger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Chicago (Chicago, Illinois)
INVENTOR(S) Maryellen L. Giger (Elmhurst, Illinois);  Zhimin Huo (Chicago, Illinois);  Carl J. Vyborny (Riverside, Illinois)
ABSTRACT A method of calculating a disease assessment by analyzing a medical image, comprising (1) extracting at least one lesion feature value from the medical image; (2) extracting at least one risk feature value from the medical image; and (3) determining the disease assessment based on the at least one lesion feature value and the at least one risk feature value. The method employs lesion characterization for characterizing the lesion, and risk assessment based on the lesion's surroundings, i.e., the environment local and distal to the lesion. Computerized methods both characterize mammographic lesions and assess the breast parenchymal pattern on mammograms, resulting in improved characterization of lesions for specific subpopulations, combining the benefits of both techniques.
FILED Monday, February 10, 2003
APPL NO 10/360814
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/132
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07124065 MacAuslan
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Speech Technology and Applied Research Corporation (Bedford, Massachusetts)
INVENTOR(S) Joel M. MacAuslan (Nashua, New Hampshire)
ABSTRACT A technique for determining the number of constraints on a set of input data, or equivalently the topological dimension, especially when such data are produced by a nonlinear system, such as a pathological vocal system or econometric data and the like. The technique characterizes the tangent space about a predetermined base point by identifying a maximal set of non-redundant nonlinear fits to the data. It needs only a modest number of data points and does not assume prior knowledge of the functional form of the true constraints, other than smoothness. Each fit is equivalent to a set of contours (including curves, surfaces, and other manifolds), with the data themselves all lying along the zero-value contour of the fit. For each fit, the gradient of the fit at the base point in the uphill direction across the contours identifies the constraint direction. Considering all fits simultaneously, the number of constraint directions that are linearly independent provides the number of constraints in the neighborhood of the base point. The remaining unconstrained directions define the tangent space, and its dimensionality, which is precisely the number of linearly independent unconstrained directions, is precisely the inferred topological dimensionality of the original data.
FILED Monday, September 15, 2003
APPL NO 10/662991
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/2
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US 07124068 Pavletich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S) Nikola Pavletich (New York, New York);  Michael Finnin (Alexandria, Virginia);  Jill Donigian (North Arlington, New Jersey);  Victoria M. Richon (Rye, New York);  Richard A. Rifkind (New York, New York);  Paul A. Marks (Washington, Connecticut);  Ronald Breslow (Englewood, New Jersey)
ABSTRACT The present invention provides three-dimensional structural information from the hyperthermophilic bacterium Aquifex aeolicus which is a histone deacetylase-like protein (HDLP). HDLP shares 35.2% amino acid sequence identity with human histone deacetylase (HDAC1). The present invention further provides three-dimensional structural information of HDLP bound by inhibitor molecules. The three-dimensional structural information of the present invention is useful to design, isolate and screen deacetylase inhibitor compounds capable of inhibiting HDLP, HDAC family members and HDLP-related molecules. The invention also relates to nucleic acids encoding a mutant HDLP which facilitates the determination of the three-dimensional structure of HDLP in the presence of a zinc atom.
FILED Friday, March 08, 2002
APPL NO 10/095109
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/11
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE39350 Mayfield
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Stephen P. Mayfield (Cardiff, California)
ABSTRACT The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.
FILED Friday, January 16, 1998
APPL NO 10/310587
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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Department of Defense (DOD) 

US 07121401 Sinha et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Yash Sinha (Trenton, New Jersey);  Mark Benko (Greeneville, Tennessee);  Ronald Dale Turner (Chuckey, Tennessee);  Philip Kadlecek (Wilmington, Delaware);  Yuen H. Lam (Morris Plains, New Jersey);  William C. Paulo (Parsippany, New Jersey)
ABSTRACT A packaging system for a single ammunition includes a cylindrical metal container and a cap therefore. A locking mechanism locks the cap to the top end of the container and a guiding mechanism guides the cap onto the top end of the container before the locking mechanism is locked to assure proper alignment. A plurality of impact rings are located laterally about the container and the cap to provide impact protection therefore. A stacking mechanism for each container allows a plurality of the containers to be securely stacked adjacent one another. The stacking mechanism includes a first top member and a second top member located adjacent the top ring and located 180° from one another about the cap such that the first top member of one cap interlocks with the second top member of an adjacent cap, and a similar arrangement on the bottom ring of the container.
FILED Tuesday, November 25, 2003
APPL NO 10/707168
ART UNIT 3728 — Fluid Handling and Dispensing
CURRENT CPC
Special receptacle or package
26/3
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US 07121448 Subramanian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Pazhayannur Ramanathan Subramanian (Niskayuna, New York);  Earl Claude Helder (Cincinnati, Ohio);  Timothy Joseph Trapp (Upper Arlington, Ohio);  Mark Lawrence Hunt (Greenville, South Carolina);  Timothy V Stotler (Columbus, Ohio)
ABSTRACT The present invention provides a friction stir welding apparatus and associated thermal management systems and methods for joining one or more similar or dissimilar materials forming a workpiece along a joint to be welded. The friction stir welding apparatus includes a pin tool apparatus selectively disposed adjacent to and in direct contact with a first surface of the workpiece along the joint to be welded and a heating member disposed adjacent to a second surface of the workpiece along the joint to be welded, the heating member operable for controllably heating at least a portion of the workpiece adjacent to the joint to be welded. The friction stir welding apparatus also includes an annular spindle having an interior portion and an axis, the interior portion of the annular spindle at least partially defining one or more cooling channels, the one or more cooling channels operable for containing a cooling fluid. The friction stir welding apparatus further includes a shoulder disposed adjacent to the annular spindle and substantially aligned with the axis of the annular spindle and a pin tool disposed adjacent to the shoulder and substantially aligned with the axis of the annular spindle. The cooling fluid is operable for cooling at least one of the shoulder and the pin tool.
FILED Friday, August 29, 2003
APPL NO 10/651397
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Metal fusion bonding
228/2.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07121800 Beattie
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Jeffrey Beattie (West Hartford, Connecticut)
ABSTRACT A turbine blade damper seal assembly includes a seal and a damper that both abut a radially outermost non-gas path surface. The seal is fabricated from a plastically deformable material and nests within a recess of the damper. The damper is fabricated from a rigid material that absorbs vibrational energy generated during operation. The recess within the damper provides for both the damper and the seal to be positioned at the radially outermost non-gas path surface.
FILED Monday, September 13, 2004
APPL NO 10/939766
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/190
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122117 Goldring et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jeffrey S. Goldring (Annapolis, Maryland);  Daniel M. Bergen, Jr. (Linthicum, Maryland)
ABSTRACT A self-cleaning composite deck drain apparatus which includes a removable top part having a top grating surface for receiving waste liquid and a trap for catching particulate matter from the liquid at a lower end. The drain apparatus further includes a bottom part having a drainpipe within an annular chamber formed thereabout for receiving and holding the top part. Circumferentially spaced locking tabs are affixed to the edge of the top part below the grating surface thereof for reception within tab receivers in the bottom part when the top part is inserted into the chamber of the bottom part and turned for locking of the tabs within the tab receivers. The top part includes a threaded bore within which a valve is manually operable to open and close the drainpipe. The deck drain apparatus is made of composite plastic materials to resist corrosion.
FILED Thursday, October 28, 2004
APPL NO 10/975125
ART UNIT 3617 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/163
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122149 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Lixiong Li (Panama City, Florida);  Timothy J. Campbell (Panama City, Florida);  Robert K. Nichols, Jr. (Panama City, Florida);  Kristopher S. Cozart (Panama City, Florida)
ABSTRACT A fluid processor, suitable for the production of sterile water for injection, having a processor assembly and a process control system comprising a pump, a flow splitter, flow restrictors and a pressure relief valve. In a preferred embodiment, the processor assembly comprises a heat exchanger, a reactor and a heater arranged in a nested configuration. The preferred embodiment of the present invention also include a treatment assembly having a combination of filter, reverse osmosis and ion exchange devices and further incorporates an assembly and method allowing for the in situ sanitization of the fluid processor during cold start and shutdown to prevent bacteria growth during storage of the fluid processor. The fluid processor may include an electronic control system comprising a touch screen operator interface, a programmable logic controller and sensors for measuring temperature, pressure, flow rate, conductivity and endotoxin level.
FILED Friday, July 11, 2003
APPL NO 10/618133
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/26
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122152 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) University of Florida (Gainesville, Florida);  The California Institute of Technology (Pasadena, California);  Aerovironment, Inc. (Monrovia, California)
INVENTOR(S) Nathan S. Lewis (La Canada, California);  Michael S. Freund (Altadena, California);  Shawn M. Briglin (Pasadena, California);  Phil Tokumaru (Moorpark, California);  Charles R. Martin (Gainesville, Florida);  David T. Mitchell (Gainesville, Florida)
ABSTRACT Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed.
FILED Tuesday, April 24, 2001
APPL NO 09/842204
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122522 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) CLF Medical Technology Acceleration Program, Inc. (Clifton Park, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  James A. Bennett (Delmar, New York);  Herbert I. Jacobson (Albany, New York);  Fassil B. Mesfin (Albany, New York)
ABSTRACT Therapeutic compounds which are cell proliferation modulators, preferably inhibitors. These modulators contain amino acid structures that are arranged as a hydrophilic analog of an alpha-fetoprotein. The modulator may be a peptide itself, e.g., an octapeptide like that of SEQ ID NO: 5; a peptidomimetic; or may be in the form of a pharmaceutically acceptable scaffold, such as a polycyclic hydrocarbon to which is attached the necessary amino acid structures for biological and/or chemical activity. The modulators of the invention are distinguished in one aspect over previous compounds in that they are orally active, and therefore do not have to be injected into the patient. The compositions and methods are useful for reducing estrogen-stimulated growth of cells, and treating or preventing cancer, such as breast cancer. The treatment or prevention methods can include the use of tamoxifen therapy in combination with the peptide therapy.
FILED Wednesday, November 20, 2002
APPL NO 10/300530
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/15
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122598 Naciri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jawad Naciri (Herndon, Virginia);  Hong Jeon (Carlsbad, California);  Patrick Keller (Bures sur Yvette, France);  Banahalli R. Ratna (Woodbridge, Virginia)
ABSTRACT A method of making a liquid crystalline fiber is disclosed. A copolymer having a liquid crystalline side group and a crosslinking side group is crosslinked. A fiber of the crosslinking copolymer is drawn before the crosslinking reaction is complete.
FILED Wednesday, August 18, 2004
APPL NO 10/923154
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
525/63
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122626 Ge et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) GeneSoft Pharmceuticals, Inc. (South San Francisco, California)
INVENTOR(S) Yigong Ge (So. San Francisco, California);  Matthew J. Taylor (San Francisco, California);  Eldon E. Baird (Half Moon Bay, California);  Roland W. Bürli (San Francisco, California);  Jacob A. Kaizerman (Redwood City, California);  Amanda E. Martin (San Francisco, California);  Brie Cadman (Napa, California)
ABSTRACT Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds. A representative thienyl compound has the structure
FILED Wednesday, April 24, 2002
APPL NO 10/132887
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122703 Saxon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Eliana Saxon (Albany, California);  Carolyn Bertozzi (Berkeley, California)
ABSTRACT The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
FILED Thursday, March 06, 2003
APPL NO 10/384099
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
568/17
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122734 Fetzer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Christopher M. Fetzer (Saugus, California);  James H. Ermer (Burbank, California);  Richard R. King (Thousand Oaks, California);  Peter C. Cotler (Canyon Country, California)
ABSTRACT A method of reducing propagation of threading dislocations into active areas of an optoelectronic device having a III–V material system includes growing a metamorphic buffer region in the presence of an isoelectronic surfactant. A first buffer layer may be lattice matched to an adjacent substrate and a second buffer layer may be lattice matched to device layers disposed upon the second buffer layer. Moreover, multiple metamorphic buffer layers fabricated in this manner may be used in a single given device allowing multiple layers to have their band gaps and lattice constants independently selected from those of the rest of the device.
FILED Wednesday, October 23, 2002
APPL NO 10/281302
ART UNIT 1753 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/252
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122783 Pastore, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Robert A. Pastore, Jr. (Freehold, New Jersey);  John A. Kosinski (Neptune, New Jersey);  Hong-Liang Cui (Basking Ridge, New Jersey);  Yan Zhang (Newark, New Jersey);  Zhifan Yin (North Arlington, New Jersey);  Bingquan Chen (Hoboken, New Jersey)
ABSTRACT Fiber Bragg gratings (FBG) seismic activity sensors coupled in sensor arrays provide increased sensitivity to seismic activities, lower strain values and an absence of EMI allowing detection of troop and vehicle movements based on ground vibrations generating seismic signals. The FBG sensor head features a spring-mass configuration with a head surface, fiber optic cable and the FBG sensor attached to a spring that stretches during the acceleration of the mass. Waves propagating inside the earth and along the ground arriving at the sensor locations cause movement of the seismic activity sensors embedded in the ground and this movement induces an acceleration-dependent change in the FBG gratings placed on the sensors. In multiple sensor configurations, the cable will be connected to the other sensors in the network. FBG sensors, sensor arrays and sensor methods are provided in several embodiments.
FILED Tuesday, November 02, 2004
APPL NO 10/985077
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/227.140
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122926 Tesar
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Delbert Tesar (Austin, Texas)
ABSTRACT A fault-tolerant actuator module, in a single containment shell, containing two actuator subsystems that are either asymmetrically or symmetrically laid out is provided. Fault tolerance in the actuators of the present invention is achieved by the employment of dual sets of equal resources. Dual resources are integrated into single modules, with each having the external appearance and functionality of a single set of resources.
FILED Thursday, September 18, 2003
APPL NO 10/665729
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/75.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123038 Ho et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Sun Microsystems, Inc. (Santa Clara, California)
INVENTOR(S) Ronald Ho (Mountain View, California);  Robert J. Drost (Mountain View, California)
ABSTRACT One embodiment of the present invention provides a system that performs voltage sampling over an extended voltage range on a semiconductor chip. During operation, the system receives an input voltage at a node within the semiconductor chip. The system samples the input voltage through a first sampling pathway using NMOS pass gates, which latch the input voltage to produce a first output signal. This first output signal tracks the input voltage from ground up to a cut-off voltage for the nMOS pass gates. The system also samples the input voltage through a second sampling pathway using nMOS pass gates, which latch the input voltage to produce a second output signal. Prior to the NMOS pass gates along the second sampling pathway, the input voltage passes through a source-follower gate, which translates the input voltage down, so that the second output signal tracks the input voltage from a turn-on voltage of the source-follower gate up to Vdd. Next, the system combines the first and second output signals to produce a combined output signal, which tracks the input voltage over the extended voltage range from ground to Vdd.
FILED Wednesday, December 17, 2003
APPL NO 10/739473
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Electricity: Measuring and testing
324/763
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123359 Armstrong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arrowhead Center, Inc. (Las Cruces, New Mexico)
INVENTOR(S) Robert L. Armstrong (Las Cruces, New Mexico);  Vladimir M. Shalaev (West Lafayette, Indiana);  Harold V. Smith (Las Cruces, New Mexico);  Andrey K. Sarychev (West Lafayette, Indiana);  Z. Charles Ying (Boyds, Maryland)
ABSTRACT An optical sensing enhancing material (and corresponding method of making) comprising: a medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals; and a microcavity, wherein the medium is located in a vicinity of the microcavity. Also an optical sensor and sensing method comprising: providing a doped medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals, with the material; locating the doped medium in the vicinity of a microcavity; exciting the doped medium with a light source; and detecting light reflected from the doped medium. Also an optical sensing enhancing material comprising a medium, the medium comprising a semicontinuous metal film of randomly distributed metal particles and their clusters at approximately their percolation threshold. The medium preferably additionally comprises a microcavity/microresonator. Also devices and methods employing such material.
FILED Friday, September 12, 2003
APPL NO 10/661319
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123544 Kuklinski
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Kuklinski (Portsmouth, Rhode Island)
ABSTRACT An assembly for determining speed of a supercavitating underwater vehicle during underwater travel includes a fin mounted on the vehicle aft of a cavitator portion of the vehicle and adapted to be extended outwardly beyond a hull of the vehicle and through a boundary of a gas-filled cavity around the vehicle to form a disturbance in the cavity boundary, which disturbance propagates along the boundary. An acoustic transmitter is mounted on the vehicle and directs acoustic energy toward the boundary and the disturbance. An acoustic receiver is mounted on the vehicle and receives acoustic energy reflected off the disturbance. An autopilot is mounted on the vehicle and clocks times of projection of the fin and acoustic transmission receptions of reflected acoustic energy to determine the speed of the vehicle through the water.
FILED Monday, May 24, 2004
APPL NO 10/857374
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/89
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123725 Boesch, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Harold E. Boesch, Jr. (Beltsville, Maryland);  Bruce T. Benwell (Sumerduck, Virginia);  Christian G. Reiff (Arlington, Virginia)
ABSTRACT An apparatus and method are provided for high intensity acoustic test cells that employ the Helmholtz resonator principle, incorporating at least one moderately-sized volume or test cell that is tunable to a given infrasonic to low-sonic frequency and generates sound of high intensity with very pure sinusoidal waveforms in this test cell or volume, by varying the geometry of a port which is connected to the test volume and open to either atmosphere or a second or input volume and by introducing to the test volume or the input volume a driving acoustic signal at the given tuned frequency. The apparatus and method are used for testing or performing experiments on materials, structures, devices, products, biological entities or humans at high acoustic intensities and frequencies in the low-sonic to infrasonic ranges.
FILED Friday, December 29, 2000
APPL NO 09/749861
ART UNIT 2615 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Electrical audio signal processing systems and devices
381/58
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07121765 Nickelson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Reva A. Nickelson (Shelley, Idaho);  John G. Richardson (Idaho Falls, Idaho);  Kevin M. Kostelnik (Idaho Falls, Idaho);  Paul A. Sloan (Rigby, Idaho)
ABSTRACT Systems, components, and methods relating to subterranean containment barriers. Laterally adjacent tubular casings having male interlock structures and multiple female interlock structures defining recesses for receiving a male interlock structure are used to create subterranean barriers for containing and treating buried waste and its effluents. The multiple female interlock structures enable the barriers to be varied around subsurface objects and to form barrier sidewalls. The barrier may be used for treating and monitoring a zone of interest.
FILED Monday, November 14, 2005
APPL NO 11/273732
ART UNIT 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Hydraulic and earth engineering
45/129.650
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07121795 Moroz et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Emilian Mieczyslaw Moroz (San Diego, California);  Kirk Gee Pierce (Simpsonville, South Carolina)
ABSTRACT A method for reducing at least one of loads, deflections of rotor blades, or peak rotational speed of a wind turbine includes storing recent historical pitch related data, wind related data, or both. The stored recent historical data is analyzed to determine at least one of whether rapid pitching is occurring or whether wind speed decreases are occurring. A minimum pitch, a pitch rate limit, or both are imposed on pitch angle controls of the rotor blades conditioned upon results of the analysis.
FILED Wednesday, June 30, 2004
APPL NO 10/880714
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122106 Lin et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Yuehe Lin (Richland, Washington);  Liang Liang (Fontana, California);  Jun Liu (Richland, Washington)
ABSTRACT A method for producing an array of oriented nanofibers that involves forming a solution that includes at least one electroactive species. An electrode substrate is brought into contact with the solution. A current density is applied to the electrode substrate that includes at least a first step of applying a first substantially constant current density for a first time period and a second step of applying a second substantially constant current density for a second time period. The first and second time periods are of sufficient duration to electrically deposit on the electrode substrate an array of oriented nanofibers produced from the electroactive species. Also disclosed are films that include arrays or networks of oriented nanofibers and a method for amperometrically detecting or measuring at least one analyte in a sample.
FILED Thursday, May 23, 2002
APPL NO 10/154935
ART UNIT 1753 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/109
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122128 Comanzo et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Holly Ann Comanzo (Niskayuna, New York);  Venkatesan Manivannan (Rexford, New York);  Alok Mani Srivastava (Niskayuna, New York);  William Winder Beers (Chesterland, Ohio)
ABSTRACT A phosphor comprises a borate of terbium, at least an alkaline-earth metal, and at least a Group-3 metal. In one embodiment, the phosphor has a formula of A3(D1-xTbx)3(BO3)5; wherein A is at least an alkaline-earth metal selected from the group consisting of calcium, barium, strontium, and magnesium; D is at least a Group-3 metal selected from the group consisting of lanthanum, scandium, and yttrium; and 0<x<0.5. The phosphor can be used in light sources such as those based on mercury discharge or light-emitting diodes and in displays.
FILED Thursday, April 29, 2004
APPL NO 10/834142
ART UNIT 1755 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compositions
252/301.4R0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122152 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) University of Florida (Gainesville, Florida);  The California Institute of Technology (Pasadena, California);  Aerovironment, Inc. (Monrovia, California)
INVENTOR(S) Nathan S. Lewis (La Canada, California);  Michael S. Freund (Altadena, California);  Shawn M. Briglin (Pasadena, California);  Phil Tokumaru (Moorpark, California);  Charles R. Martin (Gainesville, Florida);  David T. Mitchell (Gainesville, Florida)
ABSTRACT Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed.
FILED Tuesday, April 24, 2001
APPL NO 09/842204
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122164 Nenoff et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Tina M. Nenoff (Albuquerque, New Mexico);  May D. Nyman (Albuquerque, New Mexico)
ABSTRACT Niobate-based octahedral molecular sieves having significant activity for multivalent cations and a method for synthesizing such sieves are disclosed. The sieves have a net negatively charged octahedral framework, comprising niobium, oxygen, and octahedrally coordinated lower valence transition metals. The framework can be charge balanced by the occluded alkali cation from the synthesis method. The alkali cation can be exchanged for other contaminant metal ions. The ion-exchanged niobate-based octahedral molecular sieve can be backexchanged in acidic solutions to yield a solution concentrated in the contaminant metal. Alternatively, the ion-exchanged niobate-based octahedral molecular sieve can be thermally converted to a durable perovskite phase waste form.
FILED Thursday, May 01, 2003
APPL NO 10/427249
ART UNIT 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry of inorganic compounds
423/21.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122261 Morse et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeffrey D. Morse (Martinez, California);  Alan F. Jankowski (Livermore, California);  Conrad Yu (Antioch, California)
ABSTRACT Disclosed herein is a metal hydride fuel storage cartridge having integrated resistive heaters that can be used in conjunction with fuel cells such as MEMS-based fuel cells. The cartridge is fabricated using micromachining methods and thin/thick film materials synthesis techniques.
FILED Friday, February 21, 2003
APPL NO 10/371876
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/17
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122341 Liao
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Food Industry Research and Development Institute (Hsinchu, Taiwan)
INVENTOR(S) James C. Liao (Los Angeles, California)
ABSTRACT The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous polypeptides and metabolites.
FILED Thursday, July 27, 2000
APPL NO 10/048186
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/67
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122343 Petrini et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John H. J. Petrini (Madison, Wisconsin);  William Francis Morgan (Mill Valley, California);  Richard Scott Maser (Madison, Wisconsin);  James Patrick Carney (El Cerrito, California)
ABSTRACT An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.
FILED Wednesday, April 18, 2001
APPL NO 09/837138
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122502 Teter et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David M. Teter (Edgewood, New Mexico);  Patrick V. Brady (Albuquerque, New Mexico);  James L. Krumhansl (Albuquerque, New Mexico)
ABSTRACT A process and medium for decontamination of water containing anionic species including arsenic and chromium, wherein compounds comprising divalent and trivalent metal oxides and sulfides are used to form surface complexes with contaminants under pH conditions within the range of potable water. In one embodiment natural and synthetic spinels and spinel-like materials are used as the sorbent substance.
FILED Thursday, September 30, 2004
APPL NO 10/955291
ART UNIT 1754 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122703 Saxon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Eliana Saxon (Albany, California);  Carolyn Bertozzi (Berkeley, California)
ABSTRACT The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
FILED Thursday, March 06, 2003
APPL NO 10/384099
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
568/17
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122736 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Midwest Research Institute (Kansas City, Missouri)
INVENTOR(S) Qi Wang (Littleton, Colorado);  Eugene Iwaniczko (Lafayette, Colorado)
ABSTRACT A thin-film solar cell is provided. The thin-film solar cell comprises an a-SiGe:H (1.6 eV) n-i-p solar cell having a deposition rate of at least ten (10) Å/second for the a-SiGe:H intrinsic layer by hot wire chemical vapor deposition. A method for fabricating a thin film solar cell is also provided. The method comprises depositing a n-i-p layer at a deposition rate of at least ten (10) Å/second for the a-SiGe:H intrinsic layer.
FILED Thursday, August 16, 2001
APPL NO 10/485715
ART UNIT 1753 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/258
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122926 Tesar
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Delbert Tesar (Austin, Texas)
ABSTRACT A fault-tolerant actuator module, in a single containment shell, containing two actuator subsystems that are either asymmetrically or symmetrically laid out is provided. Fault tolerance in the actuators of the present invention is achieved by the employment of dual sets of equal resources. Dual resources are integrated into single modules, with each having the external appearance and functionality of a single set of resources.
FILED Thursday, September 18, 2003
APPL NO 10/665729
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/75.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123032 Yakymyshyn et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) FieldMetrics, Inc. (Seminole, Florida)
INVENTOR(S) Christopher Paul Yakymyshyn (Seminole, Florida);  Pamela Jane Yakymyshyn (Seminole, Florida);  Michael Allen Brubaker (Loveland, Colorado)
ABSTRACT A voltage sensor is described that consists of an arrangement of impedance elements. The sensor is optimized to provide an output ratio that is substantially immune to changes in voltage, temperature variations or aging. Also disclosed is a material with a large and stable dielectric constant. The dielectric constant can be tailored to vary with position or direction in the material.
FILED Friday, December 03, 2004
APPL NO 10/904899
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/705
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123160 Hall et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) IntelliServ, Inc. (Provo, Utah)
INVENTOR(S) David R. Hall (Provo, Utah);  David B. Bartholomew (Springville, Utah);  Monte L. Johnson (Orem, Utah);  Justin Moon (Bountiful, Utah);  Roger O. Koehler (Provo, Utah)
ABSTRACT A method for triggering an action of at least one downhole device on a downhole network integrated into a downhole tool string synchronized to an event comprises determining latency, sending a latency adjusted signal, and performing the action. The latency is determined between a control device and the at least one downhole device. The latency adjusted signal for triggering an action is sent to the downhole device. The action is performed downhole synchronized to the event. A preferred method for determining latency comprises the steps: a control device sends a first signal to the downhole device; after receiving the signal, the downhole device sends a response signal to the control device; and the control device analyzes the time from sending the signal to receiving the response signal.
FILED Tuesday, August 10, 2004
APPL NO 10/710878
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/853.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123364 Deason et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Vance A. Deason (Idaho Falls, Idaho);  Kenneth L. Telschow (Idaho Falls, Idaho)
ABSTRACT An imaging system includes: an object wavefront source and an optical microscope objective all positioned to direct an object wavefront onto an area of a vibrating subject surface encompassed by a field of view of the microscope objective, and to direct a modulated object wavefront reflected from the encompassed surface area through a photorefractive material; and a reference wavefront source and at least one phase modulator all positioned to direct a reference wavefront through the phase modulator and to direct a modulated reference wavefront from the phase modulator through the photorefractive material to interfere with the modulated object wavefront. The photorefractive material has a composition and a position such that interference of the modulated object wavefront and modulated reference wavefront occurs within the photorefractive material, providing a full-field, real-time image signal of the encompassed surface area.
FILED Tuesday, October 08, 2002
APPL NO 10/267237
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/502
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE39350 Mayfield
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Stephen P. Mayfield (Cardiff, California)
ABSTRACT The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.
FILED Friday, January 16, 1998
APPL NO 10/310587
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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National Science Foundation (NSF) 

US 07122229 Camacho-Lopez et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Kent State University (Kent, Ohio)
INVENTOR(S) Miguel Angel Camacho-Lopez (Tenancingo Edo., Mexico);  Peter Palffy-Muhoray (Kent, Ohio);  Michael J. Shelley (New York, New York)
ABSTRACT A method for inducing movement of an object in contact with a fluid, includes providing a flexible object, and exposing the object to an energy source. The energy source induces a change in the shape of the object, and movement occurs as a result of the change in shape of the object. The flexible object may be a liquid crystal elastomer object. An apparatus for producing work, including a liquid crystalline elastomer capable of changing shape upon exposure to an energy source is also disclosed.
FILED Wednesday, December 10, 2003
APPL NO 10/732880
ART UNIT 1756 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Stock material or miscellaneous articles
428/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122341 Liao
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Food Industry Research and Development Institute (Hsinchu, Taiwan)
INVENTOR(S) James C. Liao (Los Angeles, California)
ABSTRACT The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous polypeptides and metabolites.
FILED Thursday, July 27, 2000
APPL NO 10/048186
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/67
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US 07122343 Petrini et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John H. J. Petrini (Madison, Wisconsin);  William Francis Morgan (Mill Valley, California);  Richard Scott Maser (Madison, Wisconsin);  James Patrick Carney (El Cerrito, California)
ABSTRACT An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.
FILED Wednesday, April 18, 2001
APPL NO 09/837138
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122572 Gale et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, University of Texas System (Austin, Texas)
INVENTOR(S) Philip A. Gale (Austin, Texas);  Jonathan L. Sessler (Austin, Texas);  Vladimír A. Král (Praha, Czech Republic);  Andrei Andrievsky (Rochester, New York);  Vincent Lynch (Austin, Texas);  Petra I. Sansom (Edgewater, New Jersey);  William E. Allen (Austin, Texas);  Christopher T. Brown (Austin, Texas);  Andreas Gebauer (Austin, Texas)
ABSTRACT The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.
FILED Friday, April 20, 2001
APPL NO 09/838998
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/427
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122716 Gelvin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Stanton B. Gelvin (West Lafayette, Indiana);  Kirankumar S. Mysore (Ardmore, Oklahoma)
ABSTRACT Adding at least one gene involved in plant host cell T-DNA integration enhances transformation by Agrobacterium. The histone H2A gene encoded by the Arabidopsis RAT5 gene increases transformation frequencies of plants, most likely by causing overexpression of a product needed for T-DNA integration. Agrobacterium tumefaciens genetically transforms plant cells by transferring a portion of the bacterial Ti-plasmid, designated the T-DNA, to the plant, and integrating the T-DNA into the plant genome. However, not all plants are transformable by Agrobacterium and transformation frequencies may be too low to be useful. Little is known about the T-DNA integration process, and no plant genes involved in integration have been identified prior to the present invention.
FILED Thursday, March 14, 2002
APPL NO 10/098161
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/278
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US 07122823 Zeman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Social, Behavioral and Economic Sciences (SBE)
Division of Behavioral and Cognitive Sciences (BCS)
APPLICANT(S)
ASSIGNEE(S) The University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Herbert D. Zeman (Memphis, Tennessee)
ABSTRACT A radiation imaging apparatus includes a photostimulable phosphor plate, an x-ray source, a red or infrared laser, and an array of photomultiplier tubes. The x-ray source propagates x-rays toward the plate, which is incident on the plate at a first incidence angle. The x-rays interact with the plate to form a latent image therein. The laser propagates laser radiation toward the plate which is incident on the plate at a second incidence angle. According to the invention, the second incidence angle is equivalent to the first incidence angle at substantially all points on the plate. Based on the interaction of the laser radiation with the latent image in the plate, the plate emits visible image radiation. Thus, the x-ray radiation, which forms the image in the plate, follows the same path within the plate as does the laser radiation. By ensuring that the laser radiation follows the same path through the plate as the x-ray radiation, the invention achieves high spatial resolution in the image detected by the laser. The array of photomultiplier tubes receives the image radiation emitted by the plate and generates an electrical image signal based thereon. Based on this electrical image signal, the image formed in the plate may be displayed on a display device or printed on a printer. The device may also include an aspheric lens attached to the plate that refracts the laser radiation so that it enters the plate at the same incidence angle as the x-ray radiation. Using this lens, the x-ray and laser radiation may enter the plate from opposite sides of the plate and still follow the same path through the plate. Preferably, the photostimulable phosphor plate is formed of barium fluoroiodide—BaFI(Eu).
FILED Tuesday, February 08, 2005
APPL NO 11/053246
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/585
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123359 Armstrong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arrowhead Center, Inc. (Las Cruces, New Mexico)
INVENTOR(S) Robert L. Armstrong (Las Cruces, New Mexico);  Vladimir M. Shalaev (West Lafayette, Indiana);  Harold V. Smith (Las Cruces, New Mexico);  Andrey K. Sarychev (West Lafayette, Indiana);  Z. Charles Ying (Boyds, Maryland)
ABSTRACT An optical sensing enhancing material (and corresponding method of making) comprising: a medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals; and a microcavity, wherein the medium is located in a vicinity of the microcavity. Also an optical sensor and sensing method comprising: providing a doped medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals, with the material; locating the doped medium in the vicinity of a microcavity; exciting the doped medium with a light source; and detecting light reflected from the doped medium. Also an optical sensing enhancing material comprising a medium, the medium comprising a semicontinuous metal film of randomly distributed metal particles and their clusters at approximately their percolation threshold. The medium preferably additionally comprises a microcavity/microresonator. Also devices and methods employing such material.
FILED Friday, September 12, 2003
APPL NO 10/661319
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123805 Sparacin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel K. Sparacin (Cambridge, Massachusetts);  Kazumi Wada (Cambridge, Massachusetts);  Lionel C. Kimerling (Concord, Massachusetts)
ABSTRACT The light-guiding structure includes a waveguide structure that comprises a substrate and a low refractive index underclad material. The waveguide structure is oxidized to form an oxidized layer on a surface of the waveguide structure. The oxidized layer is isotropically etched after the reaction-limited oxidation regime is approaching the diffusion-limited regime and repeatedly oxidized and etched so that the waveguide structure is continuously oxidized in the reaction-limited regime, reducing the overall time of oxidation and volume of oxidized material so that the waveguide structure has its sidewall roughness reduced efficiently enabling high transmission rates of guided light.
FILED Wednesday, June 16, 2004
APPL NO 10/869636
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07124388 Wang
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Sheng-Guo Wang (Charlotte, North Carolina)
ABSTRACT There is provided a set of methods with the exact accuracy to effectively calculate the n-th order state space models of RC distributed interconnect and transmission line in closed forms in time domain and transfer functions by recursive algorithms in frequency domain, where their RC components can be evenly distributed or variously valued. The main features include simplicity and accuracy of the said closed forms of the state space models {A,B,C,D} without involving matrix inverse and matrix multiplication operations, effectiveness and accuracy of the said recursive algorithms of the transfer functions, dramatic reduction of the calculation complexity to O(n) for the state space models, simulation methodology, and practice of various model reductions and their optimization. For evenly distributed RC interconnect and transmission line, the said closed form of state space model has its computation complexity of only a fixed constant, i.e., O(1).
FILED Tuesday, January 18, 2005
APPL NO 11/037701
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/10
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07122071 Gonda et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Steve R. Gonda (Houston, Texas);  Yow-Min D. Tsao (Friendswood, Texas);  Wenshan Lee (Houston, Texas)
ABSTRACT A gas-liquid separator uses a helical passageway to impart a spiral motion to a fluid passing therethrough. The centrifugal force generated by the spiraling motion urges the liquid component of the fluid radially outward which forces the gas component radially inward. The gas component is then separated through a gas-permeable, liquid-impervious membrane and discharged through a central passageway. A filter material captures target substances contained in the fluid.
FILED Wednesday, September 25, 2002
APPL NO 10/263280
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Gas separation: Processes
095/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122152 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) University of Florida (Gainesville, Florida);  The California Institute of Technology (Pasadena, California);  Aerovironment, Inc. (Monrovia, California)
INVENTOR(S) Nathan S. Lewis (La Canada, California);  Michael S. Freund (Altadena, California);  Shawn M. Briglin (Pasadena, California);  Phil Tokumaru (Moorpark, California);  Charles R. Martin (Gainesville, Florida);  David T. Mitchell (Gainesville, Florida)
ABSTRACT Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed.
FILED Tuesday, April 24, 2001
APPL NO 09/842204
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122166 Parrish
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Clyde F. Parrish (Melbourne, Florida)
ABSTRACT Methods for concentrating hydrogen peroxide solutions have been described. The methods utilize a polymeric membrane separating a hydrogen peroxide solution from a sweep gas or permeate. The membrane is selective to the permeability of water over the permeability of hydrogen peroxide, thereby facilitating the concentration of the hydrogen peroxide solution through the transport of water through the membrane to the permeate. By utilizing methods in accordance with the invention, hydrogen peroxide solutions of up to 85% by volume or higher may be generated at a point of use without storing substantial quantities of the highly-concentrated solutions and without requiring temperatures that would produce explosive mixtures of hydrogen peroxide vapors.
FILED Tuesday, May 11, 2004
APPL NO 10/845607
ART UNIT 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry of inorganic compounds
423/584
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123359 Armstrong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arrowhead Center, Inc. (Las Cruces, New Mexico)
INVENTOR(S) Robert L. Armstrong (Las Cruces, New Mexico);  Vladimir M. Shalaev (West Lafayette, Indiana);  Harold V. Smith (Las Cruces, New Mexico);  Andrey K. Sarychev (West Lafayette, Indiana);  Z. Charles Ying (Boyds, Maryland)
ABSTRACT An optical sensing enhancing material (and corresponding method of making) comprising: a medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals; and a microcavity, wherein the medium is located in a vicinity of the microcavity. Also an optical sensor and sensing method comprising: providing a doped medium, the medium comprising a plurality of aggregated nanoparticles comprising fractals, with the material; locating the doped medium in the vicinity of a microcavity; exciting the doped medium with a light source; and detecting light reflected from the doped medium. Also an optical sensing enhancing material comprising a medium, the medium comprising a semicontinuous metal film of randomly distributed metal particles and their clusters at approximately their percolation threshold. The medium preferably additionally comprises a microcavity/microresonator. Also devices and methods employing such material.
FILED Friday, September 12, 2003
APPL NO 10/661319
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07124038 van Dam et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Cornelis P. van Dam (Davis, California);  Edward A. Mayda (Davis, California);  Roger Clayton Strawn (Mountain View, California)
ABSTRACT One embodiment of the present invention provides a system that facilitates automatically generating a performance table for an object, wherein the object is subject to fluid flow. The system operates by first receiving a description of the object and testing parameters for the object. The system executes a flow solver using the testing parameters and the description of the object to produce an output. Next, the system determines if the output of the flow solver indicates negative density or pressure. If not, the system analyzes the output to determine if the output is converging. If converging, the system writes the output to the performance table for the object.
FILED Thursday, December 02, 2004
APPL NO 11/004716
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/50
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07121040 Wiese et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Adam H. Wiese (Harshaw, Wisconsin);  Daniel A. Netzer (Rhinelander, Wisconsin);  Don Riemenschneider (Rhinelander, Wisconsin)
ABSTRACT Method and apparatus for applying liquids to foliage with a roller and adjustable spray nozzle apparatus. A large heavy roller is pulled or pushed across a field of plants, thereby forcing the plants very close to the ground. A height adjustable applicator nozzle directly following the roller can be adjusted very close to the compacted plants. The combination of an adjustable roller and adjustable applicator nozzles allows the fluid to be released very near the plants, thereby increasing the amount of fluid transferred to the plants' surface and lowering the amount of fluid sprayed into the atmosphere. This reduces the amount of fluid required to treat a given area. The result of the invention is a savings in the cost of fluids, improved effectiveness of the treatment and an improved environmental impact where the selected fluid has a negative environmental impact.
FILED Monday, January 06, 2003
APPL NO 10/336900
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Plant husbandry
047/1.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122367 Milcamps et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees Operating Michigan State University (East Lansing, Michigan)
INVENTOR(S) Anne Milcamps (Gavirate, Italy);  David A. Pan (Scotland, United Kingdom);  Michael R. Pollard (Okemos, Michigan)
ABSTRACT The present invention relates to diacylglycerol acyltransferase genes and proteins, and methods of their use. In particular, the invention describes genes and proteins that exhibit both long-chain acyltransferase and acetyltransferase activity. The present invention encompasses both native and recombinant wild-type forms of the transferase, as well as mutants and variant forms, some of which possess altered characteristics relative to the wild-type transferase. The present invention also relates to methods of using diacylglycerol acyltransferase genes and proteins, including in their expression in transgenic organisms and in the production of acetyl-glycerides in plant oils, and in particular seed oils.
FILED Wednesday, June 02, 2004
APPL NO 10/859247
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122688 Lin et al.
FUNDED BY
Department of Agriculture (USDA)
Natural Resources Conservation Service (NRCS)
APPLICANT(S)
ASSIGNEE(S) Iowa State University Research Foundation (Ames, Iowa)
INVENTOR(S) Victor Shang-Yi Lin (Ames, Iowa);  Daniela Rodica Radu (Ames, Iowa)
ABSTRACT The present invention provides a method to prepare a fatty acid lower alkyl esters from a feedstock, such as a vegetable or an animal oil, comprising one or more fatty acid glycerol esters such as mono-, di- or tri-glycerides, and free fatty acids, comprising combining the feedstock, a lower alcohol and an acidic mesoporous silicate under conditions wherein the mesoporous silicate catalyzes the formation of the corresponding fatty acid lower alkyl ester of the free fatty acids an optionally glycerol.
FILED Monday, September 20, 2004
APPL NO 10/945559
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
554/169
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07122072 Carolan et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Air Products and Chemicals, Inc. (Allentown, Pennsylvania)
INVENTOR(S) Michael Francis Carolan (Allentown, Pennsylvania);  Matthew James Watson (Bethlehem, Pennsylvania);  Eric Minford (Laurys Station, Pennsylvania);  Stephen Andrew Motika (Kutztown, Pennsylvania);  Dale M. Taylor (Salt Lake City, Utah)
ABSTRACT Method for processing an article comprising a mixed conducting metal oxide material, which method comprises (a) contacting the article with an oxygen-containing gas and reducing or increasing the temperature of the oxygen-containing gas; (b) when the temperature of the oxygen-containing gas is reduced, reducing the oxygen activity in the oxygen-containing gas; and (c) when the temperature of the oxygen-containing gas is increased, increasing the oxygen activity in the oxygen-containing gas.
FILED Monday, November 17, 2003
APPL NO 10/714996
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Gas separation: Processes
095/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122828 Bao et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S)
ASSIGNEE(S) Lucent Technologies, Inc. (Murray Hill, New Jersey);  E.I. du Pont de Nemours and Company (Wilmington, Delaware)
INVENTOR(S) Zhenan Bao (Millburn, New Jersey);  Howard Edan Katz (Summit, New Jersey);  Jeffrey Scott Meth (Landenberg, Pennsylvania)
ABSTRACT Semiconductor apparatus comprising: a substrate having a substrate surface; a layer of a first material overlying a first region of the substrate surface; a layer of a semiconductor overlying the layer of first material and overlying a second region of the substrate surface; a first region of the layer of semiconductor, overlying the layer of first material and having a first conductivity; a second region of the layer of semiconductor, overlying the second region of the substrate surface and having a second conductivity; and the first conductivity being substantially different from the second conductivity. Such semiconductor apparatus further comprising a layer of a second material overlying the second region of the substrate surface, the second region of the layer of semiconductor overlying the layer of the second material.
FILED Wednesday, September 24, 2003
APPL NO 10/671303
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07123360 Treado et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S)
ASSIGNEE(S) ChemImage Corporation (Pittsburgh, Pennsylvania)
INVENTOR(S) Patrick J. Treado (Pittsburgh, Pennsylvania);  Matthew Nelson (Pittsburgh, Pennsylvania);  Scott Keitzer (Export, Pennsylvania)
ABSTRACT A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multitude of spatially resolved spectra of transmitted, reflected, emitted or scattered near infrared wavelength radiation light from the illuminated area of the sample is collected and a collimated beam is produced therefrom. A near infrared imaging spectrometer is provided for selecting a near infrared radiation image of the collimated beam. The filtered images are collected by a detector for further processing. The visible wavelength light from the illuminated area of the sample is simultaneously detected providing for the simultaneous visible and near infrared chemical imaging analysis of the sample. Two efficient means for performing three dimensional near infrared chemical imaging microscopy are provided.
FILED Monday, October 24, 2005
APPL NO 11/257219
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07122152 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) University of Florida (Gainesville, Florida);  The California Institute of Technology (Pasadena, California);  Aerovironment, Inc. (Monrovia, California)
INVENTOR(S) Nathan S. Lewis (La Canada, California);  Michael S. Freund (Altadena, California);  Shawn M. Briglin (Pasadena, California);  Phil Tokumaru (Moorpark, California);  Charles R. Martin (Gainesville, Florida);  David T. Mitchell (Gainesville, Florida)
ABSTRACT Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed.
FILED Tuesday, April 24, 2001
APPL NO 09/842204
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07122801 Favro et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Lawrence D. Favro (Huntington Woods, Michigan);  Robert L. Thomas (Huntington Woods, Michigan);  Xioayan Han (Plymouth, Michigan)
ABSTRACT A defect detection system for thermally imaging a structure that has been energized by sound energy. The system includes a transducer that couples a sound signal into the structure, where the sound signal causes defects in the structure to heat up. In one embodiment, a hard metal disk is positioned between the transducer and the structure to help couple the sound energy from the transducer into the structure. A predetermined force is applied to the transducer and a pulse duration and a pulse frequency of the sound signal are selected so that the sound energy induces acoustic chaos in the structure, thus generating increased thermal energy. A thermal imaging camera images the structure when it is heated by the sound signal.
FILED Tuesday, September 14, 2004
APPL NO 10/940850
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/341.600
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Education (ED) 

US 07122572 Gale et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, University of Texas System (Austin, Texas)
INVENTOR(S) Philip A. Gale (Austin, Texas);  Jonathan L. Sessler (Austin, Texas);  Vladimír A. Král (Praha, Czech Republic);  Andrei Andrievsky (Rochester, New York);  Vincent Lynch (Austin, Texas);  Petra I. Sansom (Edgewater, New Jersey);  William E. Allen (Austin, Texas);  Christopher T. Brown (Austin, Texas);  Andreas Gebauer (Austin, Texas)
ABSTRACT The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.
FILED Friday, April 20, 2001
APPL NO 09/838998
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/427
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07121304 Gray, Jr.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia)
INVENTOR(S) Charles L. Gray, Jr. (Pinckney, Michigan)
ABSTRACT A hydraulic accumulator includes a rigid tank containing a flexible but non-elastic bladder formed of a metal foil and separating the interior of the tank into a gas space and a liquid space. The gas and liquid spaces respectively communicate with exterior sources of gas and liquid through fixtures provided on the accumulator tank. One of the fixtures is provided with an anti-extrusion valve to prevent the bladder from being forced out through the fixture. In one preferred embodiment the bladder is a bellows. In another preferred embodiment the accumulator tank is provided with a vent in communication with the liquid space within the tank to allow for venting of any gas separating from the liquid and accumulating within the liquid space.
FILED Wednesday, December 19, 2001
APPL NO 10/021443
ART UNIT 3754 — Fluid Handling and Dispensing
CURRENT CPC
Pipes and tubular conduits
138/30
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07123351 Schaefer
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Philip R. Schaefer (Weaverville, North Carolina)
ABSTRACT A method and device for measuring a distance to an object with light determines the distance by measuring the relative intensity of light reflected from the object and traveling over two or more paths of differing optical length or reflected from the object and traveling over two or more paths through the use of the offset angle effect. Light is emitted by one or more light sources; reflected from a surface of the object; and the reflected light is detected by one or more light detectors. The light detector(s) generate signals based on the intensity of reflected light detected and the signals are utilized to calculate the distance from the device to the object.
FILED Thursday, November 03, 2005
APPL NO 11/267234
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/4.70
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07121455 Chamberlain
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Charles R. Chamberlain (Arlington, Virginia)
ABSTRACT An embodiment of the invention provides a method for performing electronic postmarking of data, including ancillary data is provided. The method includes receiving data from a sender. The method further includes selecting ancillary data. The method further includes generating an electronic postmark including the ancillary data. The method further includes forwarding the data with the electronic postmark including the ancillary data to a receiver.
FILED Friday, April 12, 2002
APPL NO 10/474723
ART UNIT 2876 — Optics
CURRENT CPC
Registers
235/375
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07121727 Bruce et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Robert William Bruce (Loveland, Ohio);  Timothy David Distler (Batavia, Ohio)
ABSTRACT The present invention is a bushing for use in a gas turbine engine. The bushing is suitable for use in a gas turbine engine. The thickness of the bushing is increased to about 0.050 inches and the life expectancy of the bushing is at least doubled.
FILED Monday, September 13, 2004
APPL NO 10/939813
ART UNIT 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Bearings
384/297
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 17, 2006.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20061017.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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