FedInvent™ Patents
Patent Details for Tuesday, November 21, 2006
This page was updated on Sunday, March 26, 2023 at 08:06 PM GMT
Department of Health and Human Services (HHS)
| US 07137975 | Miller et al. |
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| ASSIGNEE(S) | Aciont, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | David J. Miller (Bountiful, Utah); William I. Higuchi (Salt Lake City, Utah); Kevin Li (Salt Lake City, Utah); Gordon L. Flynn (Ann Arbor, Michigan) |
| ABSTRACT | An iontophoretic method for transporting compounds of interest across a body tissue is provided. The method utilizes an AC signal in conjunction with a barrier-modifying agent such as a fatty acid, fatty alcohol, bile acid, surfactant, or the like. The method enables the maintenance of a substantially constant electrical state in a localized region of the tissue through which transport occurs, thereby allowing a compound of interest to be transported across the tissue in a controlled and predictable manner. The barrier-modifying agent reduces the time as well as the voltage level required to achieve a target electrical resistance, thereby reducing patient discomfort and increasing the battery life of the iontophoresis device. |
| FILED | Monday, December 10, 2001 |
| APPL NO | 10/014741 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/501 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138112 | Galen |
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| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | James E. Galen (Owings Mills, Maryland) |
| ABSTRACT | The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid Maintenance System. The invention optimizes the maintenance of expression plasmids at two independent levels by: (1) removing sole dependence on balanced lethal maintenance functions; and (2) incorporating at least one plasmid partition function to prevent random segregation of expression plasmids, thereby enhancing their inheritance and stability. The Plasmid Maintenance System may be employed within a plasmid which has been recombinantly engineered to express a variety of expression products. |
| FILED | Monday, September 19, 2005 |
| APPL NO | 11/229306 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138121 | Spangler et al. |
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| INVENTOR(S) | Brenda D. Spangler (Livingston, Montana); Charles W. Spangler (Livingston, Montana) |
| ABSTRACT | The present invention is directed to methods and compositions useful as biosensors that specifically interact with various pathogens and other target analytes. The biosensor itself, comprises functionalized dendritic tethers derivatized for attachment to a variety of surfaces as self-assembled monolayers (SAMs) as well as attached binding moieties (sometimes referred to as capture binding ligands). Accordingly, the present invention provides compositions comprising supports comprising surfaces to which the binding moieties (e.g. antibodies) are attached for the detection of target analytes (e.g. pathogens) as well as methods and compositions relating to the attachment of such binding moieties. |
| FILED | Friday, January 23, 2004 |
| APPL NO | 10/763413 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/178.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138227 | Kusakabe et al. |
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| INVENTOR(S) | Hirokazu Kusakabe (Asahikawa, Hokkaido 078-8373, Japan); Monika Anna Sczcygiel (Honolulu, Hawaii); David Gordon Whittingham (London SW15 3TS, United Kingdom); Ryuzo Yanagimachi (Honolulu, Hawaii); Takehito Kaneko (Honolulu, Hawaii) |
| ABSTRACT | The present invention provides a composition for freezing or freeze-drying spermatozoa or sperm heads thereof, wherein the composition enables the spermatozoa or sperm heads thereof to maintain chromosome integrity at a temperature of about +4° C. to about −200° C. Also provided is a container containing the composition. The present invention further provides a method for maintaining chromosome integrity of spermatozoa or sperm heads during freezing or freeze-drying. The present invention also provides methods for freezing or freeze-drying spermatozoa to obtain at least one spermatozoan capable of fertilizing an oocyte to produce a live offspring. Also provided are frozen or freeze-dried spermatozoa produced by these methods, and containers containing the frozen or freeze-dried spermatozoa. Finally, the present invention provides methods for producing a live mammalian offspring from an oocyte fertilized with a rehydrated freeze-dried (or thawed or freeze-thawed) spermatozoan. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/259553 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138228 | Burlingame et al. |
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| ASSIGNEE(S) | Regents of the University of California (Oakland, California); Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science (Oakland, California) |
| INVENTOR(S) | Alma L. Burlingame (Sausalito, California); Katalin F. Medzihradszky (San Francisco, California); Zsuzsanna Darula (Boulder, Colorado); Eran Perlson (Givat Shmuel, Israel); Michael Fainzilber (Rehovot, Israel); Robert J. Chalkley (San Francisco, California); Darren Tyson (Aliso Viejo, California); Ralph A. Bradshaw (Lake Forest, California) |
| ABSTRACT | Post-translational O-sulfonation of a serine or threonine residue of proteins is detected, optionally comparatively, wherein the detected O-sulfonation is detected under a first physiological condition, and is compared with a control O-sulfonation detected under a second physiological condition, and a difference between the detected and control O-sulfonations indicates a difference between the first and second physiological conditions. Predetermined changes in physiological conditions are used to infer specific changes in O-sulfonation. Proteins are modified by introducing a predetermined change in O-sulfonation at a serine or threonine residue of the protein, and optionally, detecting a resultant change in O-sulfonation. These methods include introducing or increasing O-sulfonation, eliminating or reducing O-sulfonation; and derivatizing or substituting O-sulfonation. |
| FILED | Friday, September 05, 2003 |
| APPL NO | 10/657027 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138237 | Targan et al. |
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| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stephan R. Targan (Santa Monica, California); Jonathan Braun (Tarzana, California); Christopher L. Sutton (Encinitas, California) |
| ABSTRACT | The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence of IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease. |
| FILED | Friday, May 19, 2000 |
| APPL NO | 09/575061 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138240 | Barak et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Lawrence S. Barak (Durham, North Carolina); Marc G. Caron (Hillsborough, North Carolina); Stephen S. Ferguson (London, Canada); Jie Zhang (Durham, North Carolina) |
| ABSTRACT | Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G Protein-coupled receptor kinase (GRK) activity, and compounds that interact with components of the GPCR regulatory process. |
| FILED | Thursday, May 09, 2002 |
| APPL NO | 10/141725 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138248 | Lester et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Henry A. Lester (South Pasadena, California); Norman Davidson (Sierra Madre, California); Paulo Kofuji (Pasadena, California) |
| ABSTRACT | Compositions and methods are provided for producing functional mammalian inward rectifier, G-protein activated potassium channels (Kir3.0 channels). A channel is a multimeric protein comprising one or more Kir3.0 polypeptides, e.g. Kir3.1, Kir3.2, etc., where the polypeptides may be from the same or different species. The functional channel has the distinctive features of an anomalous rectifier, in that it conducts inward but not outward K+ current; it is blocked by low concentrations of extracellular Cs+ or Ba2+; and the conductance of the channel does not depend solely on voltage, but on (E-EK). The ability of the channel to conduct inward K+ current is modulated by G-proteins, particularly G-proteins of the Gi/Go family. A number of mammalian cell surface receptors activate G-proteins as a consequence of specific ligand binding. The signal transduction from receptor to Kir3.0 channel is therefore coupled through G-protein intermediates. The functional Kir3.0 channels are useful in drug screening assays directed to modulation of cellular electrophysiology. Nucleic acids encoding Kir3.0 polypeptides are useful for expression of the gene product, and for identification of homologous genes from other species, as well as other members of the same family of proteins. Expression of the nucleic acids in a heterologous cell, e.g. Xenopus oocyte, confers the ability to cause a change in potassium flow in response to G-protein activation. |
| FILED | Monday, March 16, 1998 |
| APPL NO | 09/039927 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138253 | Szostak et al. |
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| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jack W. Szostak (Boston, Massachusetts); David S. Wilson (Hayward, California); Anthony D. Keefe (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest. |
| FILED | Thursday, October 28, 2004 |
| APPL NO | 10/975582 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138259 | Beavo et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington); University of Bern (Bern, Switzerland) |
| INVENTOR(S) | Joseph A. Beavo (Seattle, Washington); Thomas Seebeck (Ortschwaben, Switzerland); Scott Haydn Soderling (Beaverton, Oregon); Ana Rascon (Caracas, Venezuela); Roya Zoraghi (Nashville, Tennessee); Stefan Kunz (Bern, Switzerland); Kewei Gong (Los Angeles, California); Natalie Glavas (Daly City, California) |
| ABSTRACT | The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins. |
| FILED | Wednesday, September 12, 2001 |
| APPL NO | 10/380437 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/196 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138380 | De La Monte et al. |
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| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Suzanne De La Monte (East Greenwich, Rhode Island); Jack R Wands (Waban, Massachusetts) |
| ABSTRACT | Disclosed are transgenic animals and transfected cell lines expressing a protein associated with Alzheimer's Disease, neuroectodermal tumors, malignant astrocytomas, and glioblastomas. Also disclosed is the use of such transgenic animals and transfected cell lines to screen potential drug candidates for treating or preventing Alzheimer's disease, neuroectodermal tumors, malignant astrocytomas, and glioblastomas. The invention also relates to new antisense oligonucleotides, ribozymes, triplex forming DNA and external guide sequences that can be used to treat or prevent Alzheimer's disease, neuroectodermnal tumors, malignant astrocytomas, and glioblastomas. |
| FILED | Friday, September 28, 2001 |
| APPL NO | 09/964412 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138384 | Reich et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Norbert O. Reich (Santa Barbara, California); James Flynn (Goleta, California) |
| ABSTRACT | A synthetic oligonucleotide comprising a C-5 methylcytosine and which recognizes and binds an allosteric site on DNA methyltransferase thereby inhibiting DNA methyltransferase activity is disclosed. Also disclosed is a composition comprising a synthetic oligonucleotide of the invention. The composition is useful for inhibiting DNA methyltransferase activity, thereby inhibiting the methylation of DNA. The composition can be a pharmaceutical composition useful for treating disorders associated with methylation defects, such as cancer and certain developmental disorders. Also disclosed is a method of inhibiting methylation of DNA. The method involves contacting a DCMTase with a synthetic oligonucleotide of the invention in the presence of the DNA, thereby resulting in an enzyme/synthetic oligonucleotide complex. The presence of the complex prevents catalysis, thereby inhibiting DNA methyltransferase activity. Also disclosed is a method of treating a disorder of cell proliferation or development by administering to a subject a synthetic oligonucleotide of the invention. The inhibition of DNA methyltransferase prevents the methylation of DNA thereby treating the disorder of cell proliferation or development. |
| FILED | Friday, June 12, 1998 |
| APPL NO | 09/485071 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138385 | Secrist, III et al. |
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| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama) |
| INVENTOR(S) | John A. Secrist, III (Birmingham, Alabama); Kamal N. Tiwari (Birmingham, Alabama); John A. Montgomery (Birmingham, Alabama) |
| ABSTRACT | Patients suffering from cancer are treated by being administered a compound represented by the following formula: wherein each R individually is H or an aliphatic or aromatic acyl group; A is selected from the group consisting of wherein X is selected from the group consisting of hydrogen, fluorine, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano and nitro. The above compounds also inhibit DNA replication in mammalian cells. |
| FILED | Monday, September 13, 2004 |
| APPL NO | 10/938542 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138389 | Amory et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | John K. Amory (Seattle, Washington); William J. Bremner (Seattle, Washington) |
| ABSTRACT | This invention provides methods of treating a mammalian subject in need of androgen therapy by orally administering to the subject testosterone, a testosterone ester, or a testosterone precursor in an oil vehicle and by administering to the subject a modulator such as finasteride or dutasteride which increases testosterone bioavailability in the subject. |
| FILED | Monday, November 15, 2004 |
| APPL NO | 10/990118 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/171 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138493 | Dean et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michael Dean (Frederick, Maryland); Rando L. Allikmets (Cornwall-on-the-Hudson, New York); Susan E. Bates (Bethesda, Maryland); Antonio T. Fojo (Rockville, Maryland) |
| ABSTRACT | This invention provides for a novel ATP-binding cassette protein which is responsible for cytotoxin resistance. The invention also provides for methods of expressing the protein and assays for identification of inhibitors of the protein. |
| FILED | Wednesday, November 24, 1999 |
| APPL NO | 09/856927 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138497 | Houston et al. |
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| ASSIGNEE(S) | Chiron Corporation (Emeryville, California) |
| INVENTOR(S) | Lou L. Houston (Oakland, California); David B. Ring (Redwood City, California) |
| ABSTRACT | Disclosed is a formulation for targeting an epitope on an antigen expressed in a mammal. The formulation comprises a pharmaceutically acceptable carrier together with a dimeric biosynthetic construct for binding at least one preselected antigen. The biosynthetic construct contains two polypeptide chains, each of which define single-chain Fv (sFv) binding proteins and have C-terminal tails that facilitate the crosslinking of two sFv polypeptides. The resulting dimeric constructs have a conformation permitting binding of a said preselected antigen by the binding site of each said polypeptide chain when administered to said mammal. The formulation has particular utility in in vivo imaging and drug targeting experiments. |
| FILED | Thursday, June 21, 2001 |
| APPL NO | 09/887853 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138502 | Hostetter et al. |
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| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Margaret K. Hostetter (Milford, Connecticut); Denise Devore-Carter (Guilford, Connecticut) |
| ABSTRACT | Antibodies and agents which can bind to the propeptide of the Int1p protein of yeast microorganisms such as Candida albicans are provided which can be useful in methods for treating or preventing infections arising from such microorganisms. Microorganisms expressing the Int1p protein, such as C. albicans and S. cerevisiae, have shown an ability to immunomodulate host cells which allows infections of these microorganisms to thrive and become virulent. The peptide regions involved in the activation of the Int1p protein are isolated and targeted so as to provide a method of disrupting activation and allow for treatment or prevention of infection by microorganisms expressing the int1p protein. In one preferred embodiment of the invention, an antibody or agent which can bind to the propeptide of the Int1p protein from C. albicans is utilized in methods to prevent or treat infections caused by C. albicans or other microorganisms expressing the Int1p protein. |
| FILED | Friday, September 28, 2001 |
| APPL NO | 09/964858 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138503 | Tsien et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (La Jolla, California); B. Albert Griffin (Del Mar, California) |
| ABSTRACT | The present invention features biarsenical molecules. Target sequences that specifically react with the biarsenical molecules are also included. The present invention also features kits that include biarsenical molecules and target sequences. Tetraarsenical molecules are also featured in the invention. |
| FILED | Tuesday, February 03, 2004 |
| APPL NO | 10/772164 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/391.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138510 | Horvitz et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | H. Robert Horvitz (Cambridge, Massachusetts); Junying Yuan (Newton, Massachusetts); Shai Shaham (Boston, Massachusetts) |
| ABSTRACT | Described herein are genes shown to be essential for programmed cell death in C. elegans, their encoded products (RNA and polypeptides), antibodies directed against the encoded polypeptides; probes for identifying structurally related genes and bioassays for identifying functionally related cell death genes from various organisms; methods and agents for altering (increasing or decreasing) the activity of the cell death-genes and, thus, of altering cell death; and uses therefor. Specifically, two genes shown to be essential for almost all of the cell deaths which occur in the development of C. elegans, referred to as ced-3 and ced-4, have been cloned, sequenced and characterized. |
| FILED | Wednesday, December 03, 1997 |
| APPL NO | 08/984178 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138512 | Kasid et al. |
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| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Usha Kasid (Rockville, Maryland); Isamu Sakabe (Arlington, Virginia); Imran Ahmad (Wadsworth, Illinois) |
| ABSTRACT | The invention provides a SHINC-2 polynucleotide, which can be a nucleic acid encoding all or a portion of a SHINC-2 protein, or a complementary polynucleotide or antisense polynucleotide. The invention provides a SHINC-2 polypeptide, which can be a full-length SHINC-2 protein or a fragment thereof or an analog or homolog thereof. Desirably, the SHINC-2 polypeptide modulates apoptosis. The invention provides an antibody that specifically binds a SHINC-2 polypeptide. The invention provides diagnostic methods. For example, the invention affords a method for identifying compounds that modulate apoptosis. The invention provides a method for detecting or evaluating the prognosis of a cancer. The invention provides diagnostic compositions for detection of cancer. The invention provides a method of modulating apoptosis or treating or preventing a cancer, tumor growth and/or metastasis by administration of an agent that modulates the expression and/or activity of SHINC-2. The invention provides formulations of SHINC-2 polynucleotides or proteins. Preferably, such compositions will comprise liposomal formulations. |
| FILED | Thursday, April 10, 2003 |
| APPL NO | 10/411931 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138520 | Lippard et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Stephen J. Lippard (Cambridge, Massachusetts); Carmen M. Barnes (Cambridge, Massachusetts); Ariel Haskel (East Brunswick, New Jersey); Katie R. Barnes (Melrose, Massachusetts) |
| ABSTRACT | In part, the present invention is directed to coordination complexes comprising a therapeutic agent. In one aspect, the subject compositions comprise a platinum metal center and a covalently attached therapeutic agent. |
| FILED | Monday, January 12, 2004 |
| APPL NO | 10/755855 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 540/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139665 | Datta et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Deepshikha Datta (South Pasadena, California); Pin Wang (Pasadena, California); Isaac Carrico (Pasadena, California); Stephen L. Mayo (Pasadena, California); David Tirrell (Pasadena, California) |
| ABSTRACT | The instant invention provides methods, reagents, and computational tools for designing non-natural substrate analogs for enzymes, especially for designing unnatural amino acid analogs for aminoacyl tRNA Synthetases (AARSs), such as the Phe tRNA Synthetase. The instant invention also provides methods to incorporate unnatural amino acid analogs, especially those with interesting functional groups, into protein products to generate proteins of modified or novel functions. |
| FILED | Thursday, February 27, 2003 |
| APPL NO | 10/375298 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07137243 | Snyder et al. |
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| ASSIGNEE(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Philip H. Snyder (Avon, Indiana); Calvin W. Emmerson (Martinsville, Indiana) |
| ABSTRACT | A pressure wave apparatus utilizing the principles of pulsed detonation and wave rotor technologies. The apparatus includes inlet and outlet ports that interface with a plurality of fluid flow passageways on a rotor. A buffer gas is routed through some of the inlet and outlet ports and into and out of the plurality of fluid flow passageways. One of the inlet ports is a buffer gas inlet port that when placed in registry with a fluid flow passageway allows the flow of buffer gas into the respective passageway. Fuel is delivered into the buffer gas proximate the buffer gas inlet port so that only a portion of the buffer gas inlet port receives any fuel. |
| FILED | Thursday, July 03, 2003 |
| APPL NO | 10/613290 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/247 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138031 | Erickson et al. |
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| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Dave G. Erickson (Seattle, Washington); Panagiotis E. George (Sumner, Washington); Ryan C. Mortensen (Federal Way, Washington); Stuart A. Smith (Kent, Washington) |
| ABSTRACT | An apparatus and method for retaining composite structures, such as composite honeycomb structures, during manufacture are provided. The composite structure is cured on a mandrel that defines a layup surface with a grip feature. The grip feature is configured to engage the composite structure during manufacture and retain the structure in a predetermined configuration. A film adhesive can be provided between the grip feature and a tiedown ply that extends from the composite structure. |
| FILED | Tuesday, September 09, 2003 |
| APPL NO | 10/657969 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138075 | Anquetil et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Patrick A. Anquetil (Boston, Massachusetts); Ian W. Hunter (Lincoln, Massachusetts); John D. Madden (Vancouver, Canada); Peter G. Madden (Somerville, Massachusetts); Anthony E. Pullen (Belmont, Massachusetts); Timothy M. Swager (Newton, Massachusetts); Bing Xu (Kowloon, China Hong Kong); Hsiao-hua Yu (Cambridge, Massachusetts) |
| ABSTRACT | The synthesis of thiophene based conducting polymer molecular actuators, exhibiting electrically triggered molecular conformational transitions is reported. Actuation is believed to be the result of conformational rearrangement of the polymer backbone at the molecular level, not simply ion intercalation in the bulk polymer chain upon electrochemical activation. Molecular actuation results from π—π stacking of thiophene oligomers upon oxidation, producing a reversible molecular displacement that leads to surprising material properties, such as electrically controllable porosity and large strains. The existence of active molecular conformational changes is supported by in situ electrochemical data. Single molecule techniques have been used to characterize the molecular actuators. |
| FILED | Wednesday, March 19, 2003 |
| APPL NO | 10/392354 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Compositions 252/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138156 | Myrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael L. Myrick (Columbia, South Carolina); Olusola O. Soyemi (Sunnyvale, California); Paul J. Gemperline (Greenville, North Carolina) |
| ABSTRACT | Within a method of making an optical interference filter, sample spectra and measurements of a predetermined characteristic associated with respective spectra are provided. Upon selection of an initial number of filter layers and a thickness for each layer, a transmission spectrum is determined. Each sample spectrum is applied to a regression formula that relates interaction of light with the transmission spectrum to a regression value. A comparison relationship between the calculated regression values and the sample measurements is defined and optimized, wherein thickness of each layer is an optimization variable. |
| FILED | Wednesday, September 26, 2001 |
| APPL NO | 09/964194 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138599 | Petrenko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Victor F. Petrenko (Lebanon, New Hampshire) |
| ABSTRACT | An electrical conductor and a gas-filled layer are located at or near the surface of an object being deiced. The conductor carries an AC voltage that generates an alternating electric field in the gas-filled layer. A conductive layer increases the electric field strength in the gas-filled layer between the electrical conductor and the conductive layer. The alternating electric field causes electric breakdown of gas and plasma-formation in the gas-filled layer. The plasma absorbs energy released during electric discharge through the plasma, which heats ice, causing it to melt. The alternating electric field typically has a field strength in a range of about from 1 to 100 kV/cm. The AC voltage typically has an amplitude in a range of about from 10 kV to 1300 kV, and a frequency in a range of about from 50 Hz to 1 MHz. The gas-filled layer includes a plasma-forming gas selected from, among others, air, nitrogen and argon. |
| FILED | Wednesday, January 09, 2002 |
| APPL NO | 10/043752 |
| ART UNIT | 3742 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Electric heating 219/121.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138648 | Kneissl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Michael A. Kneissl (Mountain View, California); David W. Treat (San Jose, California) |
| ABSTRACT | A pair of undoped spacer layers are provided adjacent to, or near to, a single quantum well aluminum gallium nitride active region. In various exemplary embodiments, the undoped spacer layers are provided between the single quantum well aluminum gallium nitride active region and carrier confinement layers. The undoped spacer layers reduce the threshold current for the laser device and improve the output characteristics. |
| FILED | Wednesday, December 17, 2003 |
| APPL NO | 10/736643 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138743 | Sondergaard et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Neal A. Sondergaard (Severna Park, Maryland); William A. Lynch (Philadelphia, Pennsylvania) |
| ABSTRACT | The moving slip ring surface of electrical machinery transfers electrical current by contact thereof with liquid metal directly or through the tips of a plurality of closely spaced brushes positioned along the bottom of a housing under pressure within which the liquid metal is contained. The brush tips are respectively connected to lower ends of fibers electrically interconnected within the housing and exposed to the liquefied metal received and retained within the housing. According to one embodiment, the liquefied metal is retained within containment material filling the housing for contact exposure of the fibers therewith. According to another embodiment, exposure of the fibers to the liquefied metal within the housing is effected by entry of the liquefied metal into hollow brush tubes connected to and extending from the bottom of the housing, through which stem portions of the fibers extend to the brush tips. |
| FILED | Friday, November 05, 2004 |
| APPL NO | 10/985074 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/248 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138941 | Smith, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry Rosson Smith, Jr. (Arlington, Virginia) |
| ABSTRACT | Frequency calibration of a bi-static type of radar system is performed by positioning radar transmitter and receiver in spaced relation to each other over a targeted seawater surface from which radar radiation along a forward radiation scattering path is reflected toward the receiver while radar energy is also radiated along a direct path to the receiver by-passing the seawater during sequential frequency measurement tests to determine a frequency diffraction factor. A radiation blocking barrier is positioned by a floating support at a reflection location at an angular position on the seawater surface for intersection by the forward scattering path to block reflection of radar energy radiation toward the receiver during one of the measurement tests. |
| FILED | Friday, November 12, 2004 |
| APPL NO | 10/988401 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/174 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138949 | Ryken, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marvin L. Ryken, Jr. (Oxnard, California); Albert F. Davis (Ventura, California) |
| ABSTRACT | A GPS microstrip antenna designed to receive satellite provided GPS position information for use by a fourteen inch diameter projectile. The GPS microstrip antenna is configured to wrap around the projectile's body without interfering with the aerodynamic design of the projectile. The GPS microstrip antenna operates at 1.575 GHz with a bandwidth of ±10 MHz. Eight microstrip antenna elements equally spaced around the projectile provide for right hand circular polarization and a quasi-omni directional radiation pattern. |
| FILED | Wednesday, June 01, 2005 |
| APPL NO | 11/145235 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138960 | Carroll et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Joseph P. Carroll (Moorpark, California); James A. McClanahan (Woodland Hills, California) |
| ABSTRACT | A deployable electromagnetic concentrator comprises a facet stem hub assembly having at least one rotatable segment and a plurality of facets stems coupled thereto. At least one of the facet stems is coupled to at least one of the rotatable segments. The concentrator further comprises a plurality of facet stems, each being coupled to a different one of the rotatable segments for rotating the plurality of facets from a substantially overlapping configuration to a substantially non-overlapping configuration. |
| FILED | Friday, August 27, 2004 |
| APPL NO | 10/929070 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/882 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139072 | Boss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Pamela A. Boss (San Diego, California); Gregory W. Anderson (San Diego, California); Stephen H. Lieberman (La Mesa, California) |
| ABSTRACT | A thermoelectrically cooled surface-enhanced Raman Spectroscopy (TEC-SERS) fiber optic probe for real-time and in-situ monitoring of volatile organic compounds in gas, liquid, and soil environments. The TEC-SERS probe comprises a sample chamber for receiving a gas sample and a fiber optic Raman probe. The sample chamber comprises an inlet having a semipermeable membrane for separating moisture from the gas sample, a SERS substrate mounted on a thermoelectric cooler, a mass flow device for providing airflow, and an output port. The fiber optic Raman probe is operably coupled to a transparent window in the sample chamber for directing an optical excitation signal to irradiate the SERS substrate and for receiving a SERS optical signal from analytes from the gas sample that are in contact with the SERS substrate. |
| FILED | Tuesday, May 11, 2004 |
| APPL NO | 10/845415 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139221 | Carter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | G. Clifford Carter (Waterford, Connecticut); Mary H. Johnson (Middletown, Rhode Island); David J. Pistacchio (Narragansett, Rhode Island) |
| ABSTRACT | A system for close range sonar is provided. The system provides sufficient warning to permit maneuvering to avoid a close encounter even in the forward starboard/port regions, which have been problematic in the past due to ownship noise. The system utilizes a hull mounted sonar array and a towed sonar array which may be controlled in position to provide sufficient separation of noise received by both sonar arrays such that the noise is largely uncorrelated. The system utilizes beamformers for each array to supply a cross-correlator section which is able to minimize the ownship noise and maximize the signal thereby providing more time for maneuvering. The system also provides a LOFAR display and other displays that are highly sensitive to detecting close encounters. |
| FILED | Wednesday, August 11, 2004 |
| APPL NO | 10/915270 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/125 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139223 | Scarzello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John F. Scarzello (Columbia, Maryland); John J. Holmes (Columbia, Maryland); Edward C. O'Keefe (Columbia, Maryland); Robert A Wingo (Manassas, Virginia) |
| ABSTRACT | An elongated optical fiber is vertically positioned within seawater in a deep-depth targeted zone by vertical suspension thereof from a floating buoy. Electrode sensor arrays are positioned in vertically spaced relation to each other on the optical fiber for generating warning signals in response to detection of hostile conditions. The warning signals are converted into signal data collected and transferred to a transmitter in the floating buoy from which the sensor arrays are suspended within the targeted zone positioned on the optical fiber. Such collected data signals are transmitted through an antenna within the floating buoy to locations above the seawater surface for surveillance purposes. |
| FILED | Thursday, May 26, 2005 |
| APPL NO | 11/151184 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139302 | Raghavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Srinivasa H. Raghavan (Rancho Palos Verdes, California); Jack K. Holmes (Agoura Hills, California); Kris P. Maine (Redondo Beach, California) |
| ABSTRACT | A code division multiple access (CDMA) communication system using spread spectrum signaling over a communication bandwidth uses two different signal spectra generated using two different respective spreading code formats, such as NRZ code formatting and Manchester code formatting, for respectively providing nonsplit spectra having a center peak and split spectra having a center null. The spectra are combined during transmission as a CDMA communication signal having a composite spectrum. The use of different code formats produces the composite spectrum of respective center peak and center null spectra that enables increased channel capacity. |
| FILED | Monday, November 18, 2002 |
| APPL NO | 10/299541 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/141 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139458 | Koh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Corning Incorporated (Corning, New York) |
| INVENTOR(S) | Joohyun Koh (Painted Post, New York); Christine L. Tennent (Campbell, New York); Donnell T. Walton (Painted Post, New York); Ji Wang (Painted Post, New York); Luis A Zenteno (Painted Post, New York) |
| ABSTRACT | An optical fiber comprising: (i) a silica based, rare earth doped core having a first index of refraction n1; (ii) a silica based inner cladding surrounding the core having a second index of refraction n2, such that n1>n2; (iii) a silica based outer cladding surrounding the inner cladding having a third index of refraction n3 such that n2>n3, wherein inner cladding diameter is at least 125 μm. |
| FILED | Wednesday, January 19, 2005 |
| APPL NO | 11/039041 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139741 | Benjamin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael R. Benjamin (Boston, Massachusetts) |
| ABSTRACT | A mathematical programming method in which a common decision space is defined by identifying decision variables, and a set of objective functions is developed as piecewise defined functions. Each objective function is dependent on at least one of the decision variables and corresponds to a goal. The objective function has a plurality of pieces, such that the objective function has only one piece for each combination of decision variables. A value function is developed in additive preference form based on weights and the objective functions. The value function is optimized by searching through the decision variable values to find the values of the decision variables that maximize the developed value function. An action dictated by the decision variable values can then be executed. |
| FILED | Thursday, July 31, 2003 |
| APPL NO | 10/631527 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139993 | Proebsting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Robert J. Proebsting (Sonora, California); Ronald Ho (Mountain View, California); Robert J. Drost (Mountain View, California) |
| ABSTRACT | One embodiment of the present invention provides an arrangement of differential pairs of wires that carry differential signals across a semiconductor chip. In this arrangement, differential pairs of wires are organized within a set of parallel tracks on the semiconductor chip. Furthermore, differential pairs of wires are organized to be non-adjacent within the tracks. This means that each true wire is separated from its corresponding complement wire by at least one intervening wire in the set of parallel tracks, thereby reducing coupling capacitance between corresponding true and complement wires. Moreover, this arrangement may include one or more twisting structures, wherein a twisting structure twists a differential pair of wires so that the corresponding true and complement wires are interchanged within the set of parallel tracks. |
| FILED | Friday, March 26, 2004 |
| APPL NO | 10/810284 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139995 | James-Roxby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Xilinx, Inc. (San Jose, California) |
| INVENTOR(S) | Philip B. James-Roxby (Longmont, Colorado); Daniel J. Downs (Longmont, Colorado); Russell J. Morgan (Longmont, Colorado); Cameron D. Patterson (Longmont, Colorado) |
| ABSTRACT | Method and apparatus for integrating a run-time parameterizable logic core with a static circuit design. A configuration bitstream is generated from a main circuit design that is specified in a hardware description language. The main circuit design includes a first sub-circuit design that specifies a selected subset of resources of the PLD needed by the RTP core and an interface between the RTP core and other parts of the main circuit design. Via execution of a run-time reconfiguration control program, the configuration data that correspond to the first sub-circuit design are replaced with configuration data that implement the RTP core. The run-time reconfiguration program then configures the PLD with the updated configuration bitstream. |
| FILED | Tuesday, March 19, 2002 |
| APPL NO | 10/102585 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07140007 | Lamping |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Xerox Corporation (Stamford, Connecticut) |
| INVENTOR(S) | John O. Lamping (Los Altos, California) |
| ABSTRACT | Techniques that allow the operations of a program to be intercepted and intervened with are known. These techniques are restricted by the same limited view of the program's data that is currently available at a base level of an object or method. Some aspects need access to more information about the program's data of one or more objects than is available at the base level. An aspect of aspect-oriented programming systems, methods and environments examines the results of a computation at one stage. That aspect affects only subsequent stages of the computation, so that no circularity exists. Custom flow analyses, whether local or global, can also be performed at each stage to propagate non-local information. “Macro” style programming can be reduced or avoided, as programming can be facilitated in terms of manipulating the results of various computational stages instead of in terms of manipulating blocks of code. |
| FILED | Wednesday, January 16, 2002 |
| APPL NO | 10/046200 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07137839 | Dilliner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Jennifer L. Dilliner (Peoria, Illinois); Thomas M. Baker (Peoria, Illinois); Sivaprasad Akasam (Peoria, Illinois); Brian D. Hoff (East Peoria, Illinois) |
| ABSTRACT | An electrical connector includes a female component having one or more receptacles, a first test receptacle, and a second test receptacle. The electrical connector also includes a male component having one or more terminals configured to engage the one or more receptacles, a first test pin configured to engage the first test receptacle, and a second test pin configured to engage the second test receptacle. The first test receptacle is electrically connected to the second test receptacle, and at least one of the first test pin and the second test pin is shorter in length than the one or more terminals. |
| FILED | Monday, December 22, 2003 |
| APPL NO | 10/740454 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/315 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138042 | Tran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tri D. Tran (Livermore, California); David J. Lenz (Livermore, California) |
| ABSTRACT | An electrically regeneratable battery of electrochemical cells for capacitive deionization (including electrochemical purification) and regeneration of electrodes is operated at alternate polarities during consecutive cycles. In other words, after each regeneration step operated at a given polarity in a deionization-regeneration cycle, the polarity of the deionization step in the next cycle is maintained. In one embodiment, two end electrodes are arranged one at each end of the battery, adjacent to end plates. An insulator layer is interposed between each end plate and the adjacent end electrode. Each end electrode includes a single sheet of conductive material having a high specific surface area and sorption capacity, preferably a sheet formed of carbon aerogel composite. The batter further includes a plurality of generally identical double-sided intermediate electrodes that are equidistally separated from each other, between the two end electrodes. As the electrolyte enters the battery of ells, t flows through a continuous open serpentine channel defined by the electrodes, substantially parallel to the surfaces of the electrodes. By polarizing the cells, ions are removed from the electrolyte and are held in the electric double layers formed at the carbon aerogel surfaces of the electrodes. As the electrodes of each cell of the battery are saturated with the removed ions, the battery is regenerated electrically at a reversed polarity from that during the deionization step of the cycle, thus significantly minimizing secondary wastes. |
| FILED | Monday, March 15, 2004 |
| APPL NO | 10/801246 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/551 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138063 | Teter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | David M. Teter (Edgewood, New Mexico); Patrick V. Brady (Albuquerque, New Mexico); James L. Krumhansl (Albuquerque, New Mexico); Nadim R. Khandaker (Albuquerque, New Mexico) |
| ABSTRACT | An improved water decontamination process comprising contacting water containing anionic contaminants with an enhanced coagulant to form an enhanced floc, which more efficiently binds anionic species (e.g., arsenate, arsenite, chromate, fluoride, selenate, and borate, and combinations thereof) predominantly through the formation of surface complexes. The enhanced coagulant comprises a trivalent metal cation coagulant (e.g., ferric chloride or aluminum sulfate) mixed with a divalent metal cation modifier (e.g., copper sulfate or zinc sulfate). |
| FILED | Friday, February 10, 2006 |
| APPL NO | 11/351365 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/717 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138267 | Jendrisak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Epicentre Technologies Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Jerome J. Jendrisak (Madison, Wisconsin); Leslie M. Hoffman (Madison, Wisconsin); Michael J. Fiandt (Cambridge, Wisconsin); Darin Haskins (Madison, Wisconsin) |
| ABSTRACT | A method for retrofitting DNA in a single-copy or high-copy vector, such as a fosmid or BAC, whereby an artificial transposon is used to introduce a conditional multi-copy origin of replication (“ori”) into the DNA in said vector. Following random in vitro or in vivo transposition of the ori-containing transposon into DNA in the single-copy or low-copy vector, the resulting insertion clones are introduced into a special host strain that contains a gene which encodes a polypeptide required for replication from the multi-copy ori. However, since the gene for this polypeptide is expressed from a tightly-regulated inducible promoter, the polypeptide is not expressed in the absence of inducer. On addition of inducer to the culture medium, the host cell synthesizes the polypeptide, which in turn activates replication from the multi-copy ori, thereby increasing the amount of clone DNA synthesized by the cell. |
| FILED | Thursday, April 04, 2002 |
| APPL NO | 10/116886 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138462 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Barbara F. Smith (Los Alamos, New Mexico); Thomas W. Robison (Los Alamos, New Mexico) |
| ABSTRACT | A functionalized polymer for binding a dissolved molecule in an aqueous solution is presented. The polymer has a backbone polymer to which one or more functional groups are covalently linked. The backbone polymer can be such polymers as polyethylenimine, polyvinylamine, polyallylamine, and polypropylamine. These polymers are generally water-soluble, but can be insoluble when cross-linked. The functional group can be for example diol derivatives, polyol derivatives, thiol and dithiol derivatives, guest-host groups, affinity groups, beta-diphosphonic acids, and beta-diamides |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646378 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/328.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138468 | McCormick, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern Mississippi (Hattiesburg, Mississippi) |
| INVENTOR(S) | Charles L. McCormick, III (Hattiesburg, Mississippi); Andrew B. Lowe (Hattiesburg, Mississippi); Brent S. Sumerlin (Pittsburgh, Pennsylvania) |
| ABSTRACT | A new, facile, general one-phase method of generating thio-functionalized transition metal nanoparticles and surfaces modified by (co)polymers synthesized by the RAFT method is described. The method includes the stops of forming a (co)polymer in aqueous solution using the RAFT methodology, forming a colloidal transition metal precursor solution from an appropriate transition metal; adding the metal precursor solution or surface to the (co)polymer solution, adding a reducing agent into the solution to reduce the metal colloid in situ to produce the stabilized nanoparticles or surface, and isolating the stabilized nanoparticles or surface in a manner such that aggregation is minimized. The functionalized surfaces generated using these methods can further undergo planar surface modifications, such as functionalization with a variety of different chemical groups, expanding their utility and application. |
| FILED | Thursday, March 27, 2003 |
| APPL NO | 10/400346 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 526/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138615 | Williamson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | GM Global Technology Operations, Inc. (Detroit, Michigan) |
| INVENTOR(S) | Weldon S. Williamson (Malibu, California); Eugene V. Gonze (Pinckney, Michigan) |
| ABSTRACT | A microwave system having a microwave source that generates microwave signals for regenerating a diesel particulate filter (DPF) includes a sampling device that samples a power level of reflected microwave signals from the DPF and a regulator module that communicates with the microwave source and the sampling device. The regulator module further adjusts operation of the microwave source based on the power level of the reflected microwave signals and a predetermined power threshold. |
| FILED | Friday, July 29, 2005 |
| APPL NO | 11/194096 |
| ART UNIT | 3742 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Electric heating 219/679 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139218 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | IntelliServ, Inc. (Provo, Utah) |
| INVENTOR(S) | David R. Hall (Provo, Utah); H. Tracy Hall, Jr. (Provo, Utah); Joe Fox (Spanish Fork, Utah); David S. Pixton (Lehi, Utah) |
| ABSTRACT | A high-speed downhole network providing real-time data from downhole components of a drilling strings includes a bottom-hole node interfacing to a bottom-hole assembly located proximate the bottom end of a drill string. A top-hole node is connected proximate the top end of the drill string. One or several intermediate nodes are located along the drill string between the bottom-hole node and the top-hole node. The intermediate nodes are configured to receive and transmit data packets transmitted between the bottom-hole node and the top-hole node. A communications link, integrated into the drill string, is used to operably connect the bottom-hole node, the intermediate nodes, and the top-hole node. In selected embodiments, a personal or other computer may be connected to the top-hole node, to analyze data received from the intermediate and bottom-hole nodes. |
| FILED | Tuesday, August 03, 2004 |
| APPL NO | 10/710790 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/82 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139219 | Kollé et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Tempress Technologies, Inc. (Kent, Washington) |
| INVENTOR(S) | Jack J. Kollé (Seattle, Washington); Mark H. Marvin (Tacoma, Washington); Kenneth J. Theimer (Auburn, Washington) |
| ABSTRACT | This invention discloses a valve that generates a hydraulic negative pressure pulse and a frequency modulator for the creation of a powerful, broadband swept impulse seismic signal at the drill bit during drilling operations. The signal can be received at monitoring points on the surface or underground locations using geophones. The time required for the seismic signal to travel from the source to the receiver directly and via reflections is used to calculate seismic velocity and other formation properties near the source and between the source and receiver. This information can be used for vertical seismic profiling of formations drilled, to check the location of the bit, or to detect the presence of abnormal pore pressure ahead of the bit. The hydraulic negative pressure pulse can also be used to enhance drilling and production of wells. |
| FILED | Thursday, February 12, 2004 |
| APPL NO | 10/777484 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/85 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139349 | Leung |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ka-Ngo Leung (Hercules, California) |
| ABSTRACT | A spherical neutron generator is formed with a small spherical target and a spherical shell RF-driven plasma ion source surrounding the target. A deuterium (or deuterium and tritium) ion plasma is produced by RF excitation in the plasma ion source using an RF antenna. The plasma generation region is a spherical shell between an outer chamber and an inner extraction electrode. A spherical neutron generating target is at the center of the chamber and is biased negatively with respect to the extraction electrode which contains many holes. Ions passing through the holes in the extraction electrode are focused onto the target which produces neutrons by D-D or D-T reactions. |
| FILED | Monday, March 18, 2002 |
| APPL NO | 10/100955 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139677 | Hively |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Lee M. Hively (Philadelphia, Tennessee) |
| ABSTRACT | This invention teaches further method improvements to forewarn of critical events via phase-space dissimilarity analysis of data from biomedical equipment, mechanical devices, and other physical processes. One improvement involves conversion of time-serial data into equiprobable symbols. A second improvement is a method to maximize the channel-consistent total-true rate of forewarning from a plurality of data channels over multiple data sets from the same patient or process. This total-true rate requires resolution of the forewarning indications into true positives, true negatives, false positives and false negatives. A third improvement is the use of various objective functions, as derived from the phase-space dissimilarity measures, to give the best forewarning indication. A fourth improvement uses various search strategies over the phase-space analysis parameters to maximize said objective functions. A fifth improvement shows the usefulness of the method for various biomedical and machine applications. |
| FILED | Friday, July 12, 2002 |
| APPL NO | 10/195626 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07137300 | Aoyagi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Seiji Aoyagi (Suita, Japan); Yu-Chong Tai (Pasadena, California) |
| ABSTRACT | An accelerometer device comprises a dielectric seismic mass separated by a gap from an underlying comb-shaped planar capacitor. The principle for measuring acceleration detecting capacitance change according to movement of the dielectric mass in the fringe electrical field. This measuring principle is verified by FEM simulation. The simple structure of the accelerometer device allows the polymer Parylene to be used as the proof mass, greatly simplifying the technology by requiring only surface micromachining. Prototype accelerometers are fabricated and calibrated with the aid of off-chip capacitive readout IC. |
| FILED | Wednesday, March 10, 2004 |
| APPL NO | 10/798731 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/514.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07137574 | Grier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | David G. Grier (New York City, New York); Pamela T. Korda (Los Angeles, California) |
| ABSTRACT | A method and apparatus for laterally deflecting and/or separating a flow of particles using a static array of optical tweezers. In an array of optical tweezers with a lattice constant larger than the size of a particle of interest, particles driven past the array by an external force experience an additional interaction with the array of traps. By altering the angle of the array of traps relative to the external force, the particles' movement from trap to trap inside the array can be biased away from the direction of the external force, thereby enabling selective deflection and/or separation of particles. |
| FILED | Monday, June 28, 2004 |
| APPL NO | 10/878797 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/461 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138098 | Bawendi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Moungi Bawendi (Boston, Massachusetts); Nathan E. Stott (Cambridge, Massachusetts) |
| ABSTRACT | A method of manufacturing a nanocrystallite from a M-containing salt forms a nanocrystallite. The nanocrystallite can be a member of a population of nanocrystallites having a narrow size distribution and can include one or more semiconductor materials. Semiconducting nanocrystallites can photoluminesce and can have high emission quantum efficiencies. |
| FILED | Friday, October 08, 2004 |
| APPL NO | 10/959992 |
| ART UNIT | 1754 — Organic Chemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/299 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138373 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland); University of Maryland Biotechnology Institute (Baltimore, Maryland); The United States of America as represented by the Secretary of the Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Tianhong Chen (Newark, Delaware); Heather D. Embree (Baltimore, Maryland); Eleanor M. Brown (Oreland, Pennsylvania); Maryann M. Taylor (Richboro, Pennsylvania); Gregory F. Payne (Hunt Valley, Maryland) |
| ABSTRACT | Gels and polymers comprising a polypeptide bound to a polysaccharide are disclosed. Specific polypeptides include, but are not limited to, polypeptides that comprise glutamine or tyrosine residues. Specific polysaccharides include, but are not limited to, chitosan. Gels and polymers of the invention can be used for the in vitro and in situ formation of protein-polysaccharide conjugates. Methods of making polypeptide/polysaccharide gels and polymers are also disclosed. |
| FILED | Friday, September 26, 2003 |
| APPL NO | 10/529012 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138468 | McCormick, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern Mississippi (Hattiesburg, Mississippi) |
| INVENTOR(S) | Charles L. McCormick, III (Hattiesburg, Mississippi); Andrew B. Lowe (Hattiesburg, Mississippi); Brent S. Sumerlin (Pittsburgh, Pennsylvania) |
| ABSTRACT | A new, facile, general one-phase method of generating thio-functionalized transition metal nanoparticles and surfaces modified by (co)polymers synthesized by the RAFT method is described. The method includes the stops of forming a (co)polymer in aqueous solution using the RAFT methodology, forming a colloidal transition metal precursor solution from an appropriate transition metal; adding the metal precursor solution or surface to the (co)polymer solution, adding a reducing agent into the solution to reduce the metal colloid in situ to produce the stabilized nanoparticles or surface, and isolating the stabilized nanoparticles or surface in a manner such that aggregation is minimized. The functionalized surfaces generated using these methods can further undergo planar surface modifications, such as functionalization with a variety of different chemical groups, expanding their utility and application. |
| FILED | Thursday, March 27, 2003 |
| APPL NO | 10/400346 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 526/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138569 | Collmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Kansas State University Research Foundation (Manhattan, Kansas); Boyce Thompson Institute for Plant Research, Inc. (Ithaca, New York); The Institute for Genomic Research (Rockville, Maryland); The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Alan Collmer (Ithaca, New York); James R. Alfano (Lincoln, Nebraska); Xiaoyan Tang (Manhattan, Kansas); C. Robin Buell (Olney, Maryland); Gregory B. Martin (Ithaca, New York) |
| ABSTRACT | The present invention relates to isolated nucleic acid molecules encoding a type III—secreted bacterial protein capable of modifying a cell death pathway in a plant cell. One aspect of the present invention involves an isolated nucleic acid molecule having a nucleotide sequence that encodes the HopPtoD2 protein of Pseudomonas syringae pv. syringae DC 3000. Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. The nucleic acid molecules of the present invention can be used to impart disease resistance to a plant and to make a plant hypersusceptible to colonization by nonpathogenic bacteria. |
| FILED | Tuesday, April 02, 2002 |
| APPL NO | 10/114828 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138599 | Petrenko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Victor F. Petrenko (Lebanon, New Hampshire) |
| ABSTRACT | An electrical conductor and a gas-filled layer are located at or near the surface of an object being deiced. The conductor carries an AC voltage that generates an alternating electric field in the gas-filled layer. A conductive layer increases the electric field strength in the gas-filled layer between the electrical conductor and the conductive layer. The alternating electric field causes electric breakdown of gas and plasma-formation in the gas-filled layer. The plasma absorbs energy released during electric discharge through the plasma, which heats ice, causing it to melt. The alternating electric field typically has a field strength in a range of about from 1 to 100 kV/cm. The AC voltage typically has an amplitude in a range of about from 10 kV to 1300 kV, and a frequency in a range of about from 50 Hz to 1 MHz. The gas-filled layer includes a plasma-forming gas selected from, among others, air, nitrogen and argon. |
| FILED | Wednesday, January 09, 2002 |
| APPL NO | 10/043752 |
| ART UNIT | 3742 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Electric heating 219/121.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139321 | Giannakis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Georgios B. Giannakis (Minneapolis, Minnesota); Shengli Zhou (St. Paul, Minnesota) |
| ABSTRACT | Techniques are described for efficiently estimating and compensating for the effects of a communication channel in a multi-carrier wireless communication system. The techniques exploit the fact that the transmitted symbols are drawn from a finite-alphabet to efficiently estimate the propagation channel for multi-carrier communication systems, such systems using OFDM modulation. A transmitter transmits data through a communication channel according to the modulation format. A receiver includes a demodulator to demodulate the data and an estimator to estimate the channel based on the demodulated data. The channel estimator applies a power-law operation to the demodulated data to identify the channel. The techniques can be used in both blind and semi-blind modes of channel estimation. |
| FILED | Thursday, March 07, 2002 |
| APPL NO | 10/094946 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139665 | Datta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Deepshikha Datta (South Pasadena, California); Pin Wang (Pasadena, California); Isaac Carrico (Pasadena, California); Stephen L. Mayo (Pasadena, California); David Tirrell (Pasadena, California) |
| ABSTRACT | The instant invention provides methods, reagents, and computational tools for designing non-natural substrate analogs for enzymes, especially for designing unnatural amino acid analogs for aminoacyl tRNA Synthetases (AARSs), such as the Phe tRNA Synthetase. The instant invention also provides methods to incorporate unnatural amino acid analogs, especially those with interesting functional groups, into protein products to generate proteins of modified or novel functions. |
| FILED | Thursday, February 27, 2003 |
| APPL NO | 10/375298 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07138100 | Smalley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice Univesity (Houston, Texas) |
| INVENTOR(S) | Richard E. Smalley (Houston, Texas); Robert H. Hauge (Houston, Texas) |
| ABSTRACT | A continuous gas-phase method for producing single-wall carbon nanotubes at high catalyst productivity and high yield is disclosed. The method involves the use of a novel in-situ formed catalyst to initiate and grow single-wall carbon nanotubes using a carbon-containing feedstock in a high temperature and pressure process. The catalyst comprises in-situ-generated transition metal particles in contact with in-situ-generated refractory particles. The population of nucleating sites for single-wall carbon nanotubes is enhanced due to the ease of formation of a population of refractory particles. These, in turn, improve the nucleation and stability of the transition metal particles that grow on them. The larger number of transition metal particles translate into a larger number of sites for single-wall carbon nanotube production. The higher catalyst yields provide a means for obtaining higher purity single-wall carbon nanotubes. |
| FILED | Wednesday, November 20, 2002 |
| APPL NO | 10/300135 |
| ART UNIT | 1754 — Organic Chemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138253 | Szostak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jack W. Szostak (Boston, Massachusetts); David S. Wilson (Hayward, California); Anthony D. Keefe (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest. |
| FILED | Thursday, October 28, 2004 |
| APPL NO | 10/975582 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07139567 | Bokulic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Robert Steven Bokulic (Columbia, Maryland); James Robert Jensen (Columbia, Maryland) |
| ABSTRACT | This disclosure presents a communication receiver system for spacecraft that includes an open loop receiver adapted to receive a communication signal. An ultrastable oscillator (USO) and a tone detector are connected to the open loop receiver. The open loop receiver translates the communication signal to an intermediate frequency signal using a highly stable reference frequency from the USO. The tone detector extracts commands from the communication signal by evaluating the difference between tones of the communication signal. |
| FILED | Tuesday, May 18, 2004 |
| APPL NO | 10/847942 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/427 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07138180 | Denes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ferencz Denes (Madison, Wisconsin); Sorin Manolache (Madison, Wisconsin); Luis Cruz-Barba (Madison, Wisconsin) |
| ABSTRACT | Hard-carbon films with unique structures, methods for producing the films, and articles coated by the films are provided. These hard-carbon films are synthesized by the plasma surface treatment of a polymer substrate or a polymer-coated substrate in a plasma containing SFx species, where x is less than 6, and may be produced under room temperature, low pressure environments. |
| FILED | Thursday, October 16, 2003 |
| APPL NO | 10/686790 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Stock material or miscellaneous articles 428/411.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138569 | Collmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Kansas State University Research Foundation (Manhattan, Kansas); Boyce Thompson Institute for Plant Research, Inc. (Ithaca, New York); The Institute for Genomic Research (Rockville, Maryland); The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Alan Collmer (Ithaca, New York); James R. Alfano (Lincoln, Nebraska); Xiaoyan Tang (Manhattan, Kansas); C. Robin Buell (Olney, Maryland); Gregory B. Martin (Ithaca, New York) |
| ABSTRACT | The present invention relates to isolated nucleic acid molecules encoding a type III—secreted bacterial protein capable of modifying a cell death pathway in a plant cell. One aspect of the present invention involves an isolated nucleic acid molecule having a nucleotide sequence that encodes the HopPtoD2 protein of Pseudomonas syringae pv. syringae DC 3000. Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. The nucleic acid molecules of the present invention can be used to impart disease resistance to a plant and to make a plant hypersusceptible to colonization by nonpathogenic bacteria. |
| FILED | Tuesday, April 02, 2002 |
| APPL NO | 10/114828 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07138159 | Hampden-Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark J. Hampden-Smith (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); Plamen Atanassov (Albuquerque, New Mexico); Klaus Kunze (Albuquerque, New Mexico); Paul Napolitano (Albuquerque, New Mexico); Rimple Bhatia (Placitas, New Mexico); David E. Dericotte (Albuquerque, New Mexico); Paolina Atanassova (Albuquerque, New Mexico) |
| ABSTRACT | Electrocatalyst powders and methods for producing electrocatalyst powders, such as carbon composite electrocatalyst powders. The powders have a well-controlled microstructure and morphology. The method includes forming the particles from an aerosol of precursors by heating the aerosol to a relatively low temperature, such as not greater than about 400° C. |
| FILED | Monday, August 05, 2002 |
| APPL NO | 10/212991 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/376.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07138354 | Hampden-Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark J. Hampden-Smith (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); Plamen Atanassov (Albuquerque, New Mexico); Paolina Atanassova (Albuquerque, New Mexico); Klaus Kunze (Albuquerque, New Mexico); Paul Napolitano (Albuquerque, New Mexico); David Dericotte (Albuquerque, New Mexico) |
| ABSTRACT | Electrocatalyst powders and methods for producing electrocatalyst powders, such as carbon composite electrocatalyst powders. The powders have a well-controlled microstructure and morphology. The method includes forming the particles from an aerosol of precursors by heating the aerosol to a relatively low temperature, such as not greater than about 400° C. |
| FILED | Thursday, August 01, 2002 |
| APPL NO | 10/210816 |
| ART UNIT | 1755 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07138254 | Jovanovich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | GE Healthcare (SV) Corp. (Sunnyvale, California) |
| INVENTOR(S) | Stevan Bogdan Jovanovich (Livermore, California); Oscar Salas-Solano (San Francisco, California); Jeng-Thun Li (Pleasanton, California) |
| ABSTRACT | Methods for preparing nanoscale reactions using nucleic acids or proteins are presented. Nucleic acids are captured saturably, yet reversibly, on the internal surface of the reaction chamber, typically a capillary. Excess nucleic acid is removed and the reaction is performed directly within the capillary. Proteins are captured specifically and saturably on the modified inner surface of the reaction chamber, typically a capillary. Excess protein is removed and the reaction is performed directly within the capillary. Devices for effecting the methods of the invention and a system designed advantageously to utilize the methods for high throughput reactions involving nucleic acids or proteins are also provided. |
| FILED | Friday, February 07, 2003 |
| APPL NO | 10/361481 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 21, 2006.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20061121.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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