FedInvent™ Patents
Patent Details for Tuesday, December 05, 2006
This page was updated on Sunday, March 26, 2023 at 08:06 PM GMT
Department of Defense (DOD)
| US 07143634 | Major et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William R. Major (Ventura, California); Leslie A. Karr (Oak View, California) |
| ABSTRACT | A portable fuel storage tank leak detection system for detecting fuel leaks from a fuel storage tank at a leak rate of 0.1 gallons per hour. The leak detection system provides for a probability of detection of at least 95% and a probability of false alarm of no more than 5%. |
| FILED | Wednesday, December 21, 2005 |
| APPL NO | 11/316542 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/49.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143635 | Major et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William R. Major (Ventura, California); Leslie A. Karr (Oak View, California) |
| ABSTRACT | A portable fuel storage tank leak detection system for detecting fuel leaks from a fuel storage tank at a leak rate of 0.1 gallons per hour. The leak detection system provides for a probability of detection of at least 95% and a probability of false alarm of no more than 5%. |
| FILED | Friday, February 03, 2006 |
| APPL NO | 11/357463 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/49.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143656 | Wan et al. |
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| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Hong Wan (Plymouth, Minnesota); Michael L. Freeman (Woodbury, Minnesota); Charles H. Von Beck (Mesa, Arizona) |
| ABSTRACT | An improved torque sensing arrangement includes a magnetoelastic ring on a rotatable shaft, along with two or more magnetic field sensors. The ring has at least two magnetic bands magnetized in opposite directions to produce at least two magnetic fields. Alternatively, the rotatable shaft could be magnetized into bands, eliminating the need for a magnetoelastic ring. The magnetic field sensors are positioned next to, but not contacting, the bands, and can be used to measure the field strength, which can be converted to torque. The sensors are preferably positioned to either side of the peak axial magnetic field strength areas of the bands, one offset from the center of one band in a first direction and the other offset from the center of the other band in a second direction opposite the first direction, thereby limiting the average change in the reading when the fields move under the shaft. |
| FILED | Monday, December 27, 2004 |
| APPL NO | 11/023075 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/862.331 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143709 | Brennan et al. |
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| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Anthony B. Brennan (Gainesville, Florida); Ronald H. Baney (Gainesville, Florida); Michelle L. Carman (Gainesville, Florida); Thomas G. Estes (Columbia, South Carolina); Adam W. Feinberg (Gainesville, Florida); Leslie H. Wilson (Gainesville, Florida); James F. Schumacher (Gainesville, Florida) |
| ABSTRACT | A coated surface for resisting or enhancing bioadhesion includes at least one patterned polymer including coating layer having a plurality of features attached to or projected into a base surface. The features each have at least one microscale (<1 mm) dimension and have at least one neighboring feature having a substantially different geometry. The patterned coating layer preferably provides an average roughness factor (R) of from 4 to 50. The coating layer resists or enhances bioadhesion as compared to the base surface. |
| FILED | Friday, August 12, 2005 |
| APPL NO | 11/202532 |
| ART UNIT | 3617 — Printing/Measuring and Testing |
| CURRENT CPC | Ships 114/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143785 | Maerkl et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sebastian J. Maerkl (Pasadena, California); Todd A. Thorsen (Arlington, Massachusetts); Xiaoyan Bao (Pasadena, California); Stephen R. Quake (San Marino, California); Vincent Studer (Paris, France) |
| ABSTRACT | High-density microfluidic chips contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large scale integration (LSI). A component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. These integrated microfluidic networks can be used to construct a variety of highly complex microfluidic devices, for example the microfluidic analog of a comparator array, and a microfluidic memory storage device resembling electronic random access memories. |
| FILED | Wednesday, September 24, 2003 |
| APPL NO | 10/670997 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/597 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143867 | Chopra |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kewal K. Chopra (Sterling Heights, Michigan) |
| ABSTRACT | An oil level monitoring and replenishment system for use with an internal combustion engine having an oil sump. The system as a sensor which continuously measures the sump level in the reservoir for holding a quantity of oil to be used in replenishment of the sump. A sensor monitors the oil level in the sump and causes replenishment from the reservoir when needed. The reservoir has warning circuit interactive with a reservoir sensor to signal from the reservoir has reached a lower level of oil and requires the filling. The sensor also provides means to signal when the reservoir has been filled to the desired level to prevent overfilling. |
| FILED | Monday, November 24, 2003 |
| APPL NO | 10/719848 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Lubrication 184/103.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143976 | Snediker et al. |
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| ASSIGNEE(S) | Lockheed Martin Corp. (Bethesda, Maryland) |
| INVENTOR(S) | John Snediker (Owings Mills, Maryland); Michael A. Watts (Bel Air, Maryland); Grant W. Corboy (Baltimore, Maryland) |
| ABSTRACT | A UAV arresting hook is disclosed. The arresting hook facilitates the capture of a UAV via a UAV recovery system. In the illustrative embodiment, the arresting hook has a rotation block, an arm, and a plurality of latches that are disposed on the arm. The arm is coupled to the UAV via the rotation block, which provides two rotational degrees of freedom to the arm. In a stowed position, the arm is flush against the surface of the UAV. To deploy the arm, a free end of the arm is rotated away from the surface of the UAV. The arm is additionally biased to rotate about its longitudinal axis as it rotates away from the surface of the UAV. This rotation positions the latches to capture an arresting line that is part of a UAV recovery system. |
| FILED | Friday, February 04, 2005 |
| APPL NO | 11/051842 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/110.G00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143979 | Wood et al. |
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| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey H. Wood (Eureka, Missouri); Terry A. Sewell (Ballwin, Missouri) |
| ABSTRACT | An injection molded windshield is provided for a vehicle. The injection molded acrylic or polycarbonate windshield enables vehicle shape design flexibility while achieving lower aerodynamic drag. The injection molded windshields offer additional benefits for the crew by increasing visibility area with larger windshields while reducing aero noise. The vehicle includes a body and an injection molded window attached to the body. The injection molded windshield is shaped to conform to the fuselage. The injection molded windshield is formed of at least one of an injection molded acrylic or polycarbonate material. The injection molded windshield is impact and ballistic tolerant. |
| FILED | Friday, May 30, 2003 |
| APPL NO | 10/452663 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/129.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07143998 | Hall |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secrectary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Corby Vincent Hall (Chula Vista, California) |
| ABSTRACT | A vibration absorber jack including a tripod type base, a jack, an absorber positioning mechanism, and a vibration absorber holder. The jack is attached to the base, the absorber positioning mechanism disposed on top of the jack; and, the vibration absorber holder attached to the absorber positioning mechanism such that the vibration absorber holder can be positioned and moved by the absorber positioning mechanism. |
| FILED | Friday, September 12, 2003 |
| APPL NO | 10/661858 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Implements or apparatus for applying pushing or pulling force 254/98 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144057 | Young et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Stuart Young (Burke, Virginia); Richard R. Gregory, Jr. (Mount Airy, Maryland) |
| ABSTRACT | Robot and remote controlled devices have been utilized for information gathering purposes. However these robotic vehicles lack efficiency because they are not capable of operating out of doors or where the sensors and apparatus located on the robots are subject to harsh environments. The present invention provides a new and unique manner of overcoming these problems by providing a platform system that is placed upon existing robots without requiring adjustments to these devices. The platform effectuates easy installation of a plurality of sensors and apparatus on its top surface while providing internal housing for its wires and components, thereby providing a water, dirt and dust resistant environment which leads to better equipment function and ease of maintenance and repair. |
| FILED | Friday, February 18, 2005 |
| APPL NO | 11/060653 |
| ART UNIT | 3612 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Land vehicles: Bodies and tops 296/24.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144119 | Seul et al. |
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| ASSIGNEE(S) | BioArray Solutions Ltd. (Warren, New Jersey) |
| INVENTOR(S) | Michael Seul (Ferwood, New Jersey); Chiu Wo Chau (Edison, New Jersey) |
| ABSTRACT | An apparatus providing programmable illumination pattern generation for the manipulation of colloidal particulates and biomolecules in suspension between electrodes, is disclosed. The apparatus implements LEAPS (Light-controlled electrokinetic assembly of particles near surfaces), which relies on: AC electric field-induced assembly of particles the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The apparatus generates patterns of illumination and projects then onto planar surfaces, i.e., a LEAPS electrode. This enables the creation of patterns using graphical design or drawing software on a personal computer and the projection or said patterns, or sequences of patterns (“time-varying patterns”), onto the interface using a liquid crystal display (LCD) panel and an optical design which images the LCD panel onto the surface of interest, to provide for arrangements and assembly of particles in such patterns. |
| FILED | Wednesday, January 24, 2001 |
| APPL NO | 09/768413 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Optics: Image projectors 353/69 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144162 | Kumar et al. |
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| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Arun Kumar (Chandler, Arizona); Raymond J. Knorr (Tempe, Arizona) |
| ABSTRACT | A rolling element bearing anti-cavitation cage is a circular ring with a plurality of cage pockets at predetermined intervals along a circumference of the circular ring. Each of the cage pockets has at least one groove on the leading edge of the cage pocket and at least groove on the trailing edge of the cage pocket. An assembled rolling element bearing is also provided in which the rolling element bearing anti-cavitation cage has rolling elements within the cage pockets and in concentrically disposed between inner and outer races. A method for preventing cavitation during the operation of an assembled rolling element bearing using the cage is also provided. |
| FILED | Wednesday, September 15, 2004 |
| APPL NO | 10/942533 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Bearings 384/470 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144218 | Dube et al. |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | David P. Dube (Saco, Maine); Richard K. Hayford (Cape Neddick, Maine) |
| ABSTRACT | An anti-rotation lock for preventing circumferential movement of a stator segment in relation to a split case to which it is mounted is disclosed. A racetrack shaped pocket, disposed within the case and proximate the stator segment, is suitably sized to receive a lug and a spring pin. The lug is received in the pocket and protrudes radially inward from the case and is engagable by the stator segment, thus preventing circumferential movement with respect to the case. The spring pin is received adjacent to the lug and compressively retains the lug in the pocket. |
| FILED | Monday, April 19, 2004 |
| APPL NO | 10/827103 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144221 | Giffin |
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| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Rollin George Giffin (Cincinnati, Ohio) |
| ABSTRACT | A method for assembling a fan assembly for a gas turbine engine includes coupling a plurality of fan blades in a row to a rotor disk, wherein each fan blade includes an airfoil having a first sidewall and a second sidewall connected together at a leading edge and a trailing edge, and wherein each airfoil extends radially between a root and a tip. The method also includes coupling at least one shroud to at least one of the plurality of rows of fan blades, such that the shroud is coupled to at least one fan blade tip extending within the same row of fan blades, and coupling at least one row of rotor blades to the shroud, such that the rotor blades extend radially outward from the shroud. |
| FILED | Friday, July 30, 2004 |
| APPL NO | 10/903806 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144282 | Shen et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Young T. Shen (Potomac, Maryland); Edward S. Ammeen (Alexandria, Virginia) |
| ABSTRACT | The stern hull portion of a surface ship or underwater sea craft is provided with a waterjet propulsion unit having an outlet end from which a discharge propelling waterjet emerges underwater and undergoes flow beyond the stern end of the hull between a pair of twin contoured rudders normally positioned for straight forward propulsion of the hull. The contoured rudders pivotally mounted underwater on the hull are angularly displaced by maneuvering control in opposite directions from the normal positions to maneuvering positions with their lower end tips in contact with each other to form a bucket to directionally change flow of the emerging waterjet for steering, deceleration and backing purposes during hull propulsion between low and high speeds. The twin rudders are also angularly displaced by the maneuvering control in the same angular direction for a different directionally regulated change in waterjet flow to effect turning of the hull for propulsion in a reverse direction. |
| FILED | Monday, May 09, 2005 |
| APPL NO | 11/126511 |
| ART UNIT | 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Marine propulsion 440/43 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144307 | Schwartz et al. |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Brian J. Schwartz (West Hartford, Connecticut); Daniel F. Grady (Glastonbury, Connecticut); Daniel J. Wright (Glastonbury, Connecticut) |
| ABSTRACT | A process for point superabrasive machining of a nickel based material comprising the steps of providing a tool having a grinding surface coated with a superabrasive material, orienting the tool relative to a surface of the nickel based material to be machined so that there is point contact between the surface to be machined and the grinding surface, and forming a part by removing material at the point contract by rotating the tool. The tool comprises an enlarged portion, a tip portion, and a first shaft portion extending from the enlarged portion to the tip portion, the first shaft portion and the tip portion being coated with an abrasive material, and the first shaft portion having a constant diameter. |
| FILED | Thursday, March 27, 2003 |
| APPL NO | 10/400937 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Abrading 451/58 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144544 | Bulluck et al. |
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| ASSIGNEE(S) | Texas Research International, Inc. (Austin, Texas) |
| INVENTOR(S) | John W. Bulluck (Spicewood, Texas); Brad A. Rix (Spicewood, Texas) |
| ABSTRACT | An ultraviolet (UV) light curable formulation useful for repairing composite materials, comprising: an acrylic oligomer, an acrylic monomer, and a photoinitiator. This formulation may include fiberglass. The photoinitiator can be a combination of a bis-acylphosphine oxide and an alpha hydroxy ketone. The formulation can cure rapidly, such as in about 20 minutes. The cured formulation can have a Tg above 150° C. |
| FILED | Friday, February 20, 2004 |
| APPL NO | 10/784002 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144553 | Lewis et al. |
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| ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Nathan S. Lewis (La Canada, California); Erik J. Severin (Pasadena, California); Michael Freund (Altadena, California); Adam J. Matzger (Pasadena, California) |
| ABSTRACT | Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient. |
| FILED | Friday, August 29, 2003 |
| APPL NO | 10/651917 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144575 | June et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Genetics Institute, LLC (Cambridge, Massachusetts); The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Carl H. June (Merion Station, Pennsylvania); Craig B. Thompson (Merion, Pennsylvania); Gary J. Nabel (Washington, District of Columbia); Gary S. Gray (Brookline, Massachusetts); Paul D. Rennert (Millis, Massachusetts) |
| ABSTRACT | Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the absence of exogenous growth factors or accessory cells. T cell activation is accomplished by stimulating the T cell receptor (TCR)/CD3 complex or the CD2 surface protein. To induce proliferation of an activated population T cells, an accessory molecule on the surface of the T cells, such as CD28, is stimulated with a ligand which binds the accessory molecule. The T cell population expanded by the method of the invention can be genetically transduced and used for immunotherapy or can be used in methods of diagnosis. |
| FILED | Monday, March 17, 2003 |
| APPL NO | 10/390330 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.710 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144627 | Halas et al. |
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| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Nancy J. Halas (Houston, Texas); Corey J. Radloff (Houston, Texas) |
| ABSTRACT | Composite particles containing metallic shell layers are provided. The particles may include a coating layer, such as of a protective or electrically non-conducting material, over an outermost metallic shell layer. The particle preferably has a plasmon resonance associated with at least one metallic shell layer. The coating layer preferably imparts improved thermal stability to the plasmon resonance. Further, the present invention relates to particles that include at least two metallic shell layers, separated by a coating layer. The addition of a second metallic shell layer preferably allows the plasmon resonance of the shell layer to be more red-shifted with respect to a colloidal particle of the metal that the plasmon resonance of a particle of the same size but with only a single metallic shell. |
| FILED | Monday, November 05, 2001 |
| APPL NO | 10/013259 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144654 | LaFollette et al. |
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| ASSIGNEE(S) | Bipolar Technologies Corp. (Provo, Utah) |
| INVENTOR(S) | Rodney M. LaFollette (Provo, Utah); Linton G. Salmon (Shaker Heights, Ohio); John N. Harb (Orem, Utah) |
| ABSTRACT | Microscopic batteries, integratable or integrated with microelectromechanical systems or other microscopic circuits, including a MEMS microcircuit, and methods of microfabrication of such microscopic batteries are disclosed, among which comprise closed system microscopic batteries for internal storage of electricity using interval reactants only, which comprise microscopic electrodes, electrolyte and reservoir for the electrolyte. |
| FILED | Tuesday, December 10, 2002 |
| APPL NO | 10/317539 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/122 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144658 | Long et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey W. Long (Alexandria, Virginia); Debra R. Rolison (Arlington, Virginia) |
| ABSTRACT | An electrode for use in energy storage comprising a nanostructured mesoporous electrically conductive metal oxide and an ultrathin, conformal polymer coating on the metal oxide wherein said electrode has a mesoporous structure. Also disclosed is the related method for making an electrode for use in energy storage. |
| FILED | Tuesday, June 24, 2003 |
| APPL NO | 10/601881 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/223 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144701 | Huang |
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| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Tim Hui-Ming Huang (Columbia, Missouri) |
| ABSTRACT | The present invention provides a method of hybridization, differential methylation hybridization (DMH) for high throughput methylation analysis of multiple CpG island loci. DMH utilizes nucleic acid probes prepared from a cell sample to screen numerous CpG dinucleotide rich fragments affixed on a screening array. Positive hybridization signals indicate the presence of methylated sites. Methods of preparing the hybridization probes and screening array are also provided. |
| FILED | Thursday, February 21, 2002 |
| APPL NO | 10/081327 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144797 | Chow et al. |
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| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Tat-Sing Paul Chow (Niskayuna, New York); Peter Losee (Clifton Park, New York); Santhosh Balachandran (Troy, New York) |
| ABSTRACT | A semiconductor device includes a graded junction termination extension. A method for fabricating the device includes providing a semiconductor layer having a pn junction, providing a mask layer adjacent to the semiconductor layer, etching the mask layer to form at least two laterally adjacent steps associated with different mask thicknesses and substantially planar step surfaces, and implanting a dopant species through the mask layer into a portion of the semiconductor layer adjacent to the termination of the pn junction. The semiconductor layer is annealed to activate at least a portion of the implanted dopant species to form the graded junction termination extension. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/949982 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/549 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144949 | Kaner et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California); Regents of the University of California (Los Angeles, California) |
| INVENTOR(S) | Richard B. Kaner (Pacific Palisades, California); Jiaxing Huang (Los Angeles, California); Bruce H. Weiller (Santa Monica, California); Shabnam Virji (Yorba Linda, California) |
| ABSTRACT | Polymer nanofibers, such as polyaniline nanofibers, with uniform diameters less than 500 nm can be made in bulk quantities through a facile aqueous and organic interfacial polymerization method at ambient conditions. The nanofibers have lengths varying from 500 nm to 10 μm and form interconnected networks in a thin film. Thin film nanofiber sensors can be made of the polyaniline nanofibers having superior performance in both sensitivity and time response to a variety of gas vapors including, acids, bases, redox active vapors, alcohols and volatile organic chemicals. |
| FILED | Thursday, December 11, 2003 |
| APPL NO | 10/735079 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 524/800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144950 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Goleta, California) |
| ABSTRACT | Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods. |
| FILED | Wednesday, September 17, 2003 |
| APPL NO | 10/666333 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/54.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144960 | Jen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Kwan-Yue Jen (Kenmore, Washington); Larry R. Dalton (Silverdale, Washington); Jingdong Luo (Seattle, Washington); Marnie A. Haller (Seattle, Washington) |
| ABSTRACT | A crosslinkable second-order nonlinear optical polymer having one or more polarizable chromophore moieties, one or more diene moieties, and one or more dienophile or dienophile precursor moieties, wherein the diene and dienophile moieties are reactive to form 4+2 cycloaddition products; a crosslinked second-order nonlinear optical polymer having aligned, polarizable chromophore moieties and one or more 4+2 cycloaddition moieties, wherein the 4+2 cycloaddition moieties are reversibly, thermally reactive to provide diene moieties and dienophile moieties; lattices and devices that include the crosslinkable second-order nonlinear optical polymer; lattices and devices that include the crosslinked second-order nonlinear optical polymer; and methods for making the crosslinked second-order nonlinear optical polymer. |
| FILED | Thursday, January 15, 2004 |
| APPL NO | 10/758292 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/276 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144989 | Acharya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Seetharama A. Acharya (Cresskill, New Jersey); Paul K. Smith (Roscoe, Illinois); Belur N. Manjula (Cresskill, New Jersey) |
| ABSTRACT | The present invention provides pegylated hemoglobins comprising a thiocarbamoyl-phenyl-polyethylene glycol (PEG) attached to hemoglobin, and comprising a polyethylene glycol (PEG) attached to hemoglobin by an acyl group. The invention also provides methods of preparing pegylated hemoglobins using isothiocyanato phenyl carbamate of PEG and using isothiocyanato phenyl di-PEG carbamate. The invention further provides compositions and blood substitutes comprising pegylated hemoglobins and methods of treating a subject which comprise administering to the subject blood substitutes comprising non-hypertensive pegylated hemoglobins. |
| FILED | Friday, October 01, 2004 |
| APPL NO | 10/957200 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/385 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145003 | Adolph et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secrectary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Horst G. Adolph (Warrenton, Virginia); Alfred G. Stern (Upper Marlboro, Maryland) |
| ABSTRACT | A process for synthesizing 1,5-Dinosyl-3,3,7,7-tetrakis(difluoramino) octahydro-1,5-diazocine (DNTDFD) by reacting tetrahydro-1,5-bis(4-nitrobenzenesulfonyl)-1,5-diazocine-3,7-(2H, 6H) dione with HNF2/oleum initially approximately between −5 and 0 degrees C., and allowing the temperature to rise to between 10 degrees C. and ambient temperature during said reaction to initiate difluoramination producing product DNTDFD. A 2:1 mixture of FREON® 11 refrigerant and pentane or cyclopentane, or pentane alone is used as a diluent and absorbent for the reagent difluoramine. The present invention reduces the time required to produce DNTDFD from about two weeks to one to three days and reduces the need to use relatively large quantities of FREON® 11, a compound which is damaging to the environment. |
| FILED | Monday, November 24, 2003 |
| APPL NO | 10/719856 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/470 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145016 | Fronabarger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John William Fronabarger (Sun Lakes, Arizona); Michael E. Sitzmann (Adelphi, Maryland) |
| ABSTRACT | A nitrobenzodifuroxan compound having the chemical structure of: wherein two of the R1, R2, R3 and R4 comprise oxygen or are absent, and only one of R1 or R2 is present, and only one of R3 and R4 is present, and wherein x is hydrolyzed or hydrolyzable. The salt of the hydroxynitrobenzodifuroxan of this compound is useful in explosive compositions. |
| FILED | Thursday, August 28, 2003 |
| APPL NO | 10/652080 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/126 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145212 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Kevin K. Chan (Staten Island, New York); Lijuan Huang (Mountain View, California); Fenton R. McFeely (Ossining, New York); Paul M. Solomon (Yorktown Heights, New York); Hon-Sum Philip Wong (Chappaqua, New York) |
| ABSTRACT | A method (and resultant structure) of forming a semiconductor device, includes forming a metal-back-gate over a substrate and a metal back-gate, forming a passivation layer on the metal back-gate to prevent the metal back-gate from reacting with radical species, and providing an intermediate gluing layer between the substrate and the metal back-gate to enhance adhesion. |
| FILED | Thursday, June 17, 2004 |
| APPL NO | 10/868791 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/412 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145213 | Ebel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | John L. Ebel (Beavercreek, Ohio); Rebecca Cortez (Xenia, Ohio); Richard E. Strawser (Greenville, Ohio); Kevin D. Leedy (Centerville, Ohio) |
| ABSTRACT | A capacitance coupled, transmission line-fed, radio frequency MEMS switch and its fabrication process using photoresist and other low temperature processing steps are described. The achieved switch is disposed in a low cost dielectric housing free of undesired electrical effects on the switch and on the transmission line(s) coupling the switch to an electrical circuit. The dielectric housing is provided with an array of sealable apertures useful for wet, but hydrofluoric acid-free, removal of switch fabrication employed materials and also useful during processing for controlling the operating atmosphere surrounding the switch—e.g. at a pressure above the high vacuum level for enhanced switch damping during operation. Alternative arrangements for sealing an array of dielectric housing apertures are included. Processing details including plan and profile drawing views, specific equipment and materials identifications, temperatures and times are also disclosed. |
| FILED | Tuesday, July 27, 2004 |
| APPL NO | 10/901314 |
| ART UNIT | 2823 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/414 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145345 | Sarkozi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Janos Gyorgy Sarkozi (Niskayuna, New York); Nicole Andrea Evers (Niskayuna, New York) |
| ABSTRACT | A technique for detecting defects in aircraft wiring, such as for detecting partial discharges or arcing in wiring or cables is disclosed. A high frequency current transformer (HFCT) is fixingly positioned in contact with a wire so that the wire is encircled by the HFCT. Partial discharges from a damaged wire so encircled will induce a current in the HFCT proportional to the current of the discharge. The HFCT includes a conductive coil-like pattern formed onto a flexible insulating material. The insulating material has slits between each coil-turn. The HFCT also includes a core of flexible material fitted between the coil-turns through the slits. |
| FILED | Tuesday, December 23, 2003 |
| APPL NO | 10/745141 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/543 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145496 | Cho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kwang M. Cho (Rancho Palos Verdes, California); Leo H. Hui (Alhambra, California) |
| ABSTRACT | A radar on a moving platform generates an initial synthetic aperture (SAR) image of a scene from a sequence of periodic pulse returns approximately motion compensated. The SAR image is formed from pixel intensities zn(x,y) within a x,y extent of the initial synthetic aperture image. Targets are selected from the initial synthetic aperture image using a sliding window, computing a first entropy for the selected targets, and sorting the targets using the first entropy to obtain a target list having target elements, then concatenating the target elements to form a data matrix compatible in the azimuth dimension with a Fast Fourier Transform. A phase correction for autofocus is iteratively computed and applied to the initial synthetic aperture image using an inner loop, a mid loop and an outer loop. The phase correction is expressed using an orthogonal polynomial having a plurality n consecutive terms an, a2 denoting a quadratic term, and aN denoting a last order term. The outer loop, using an L index, calculates an outer loop EL(a2) entropy for the quadratic term and an outer loop EL(aN) entropy for the last order term. Iterations within the outer loop continue until EL(a2)−EL(aN) is less than an outer loop tolerance. Similarly, the mid loop, and inner loop continue until the computation of their respective entropies meet a pre-set tolerance. The inner loop entropy uses a Golden Section search for computing the inner loop entropy. |
| FILED | Tuesday, November 23, 2004 |
| APPL NO | 10/996246 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145498 | Cho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kwang M. Cho (Los Angeles, California); Leo H. Hui (Alhambra, California) |
| ABSTRACT | A moving radar generates a search mode synthetic aperture image of a patch from periodic pulse returns reflected from the patch. The patch is imaged from radar returns derived from two or more overlapping arrays. A strong scatterer is located within each array, then the data from each array is motion compensated with respect to the motion of the radar and the strong scatterer. The motion compensated results for each array are autofocused to derive a phase error for each array. Using the phase error for each array, a connected phase error estimate is computed, added to the phase error of each array to minimize the differences between phases in the overlap between arrays insuring that there is no or minimal phase discontinuity in the overlap region between arrays. Avoiding phase discontinuity yields a clear SAR image of the combination of arrays rendering the patch. |
| FILED | Wednesday, August 10, 2005 |
| APPL NO | 11/200836 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145713 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Tiejun Chang (Bozeman, Montana); Mingzhen Tian (Bozeman, Montana); William R. Babbitt (Bozeman, Montana); Kristian Merkel (Bozeman, Montana) |
| ABSTRACT | Techniques for recovering optical spectral features include receiving a detected time series that represents a temporally varying intensity of an optical signal. The optical signal is formed in response to an interaction between a target optical spectrum and a chirped optical field. The chirped optical field is an optical field that has a monochromatic frequency that varies in time. The target optical spectrum is an optical frequency dependent optical property of a material or device. A phase correction factor is determined based only on one or more properties of the chirped optical field. The detected time series is corrected based on the phase correction factor to produce an output time series that reproduces in time a shape of the target spectrum in frequency. These techniques allow for fast measurement of spectral features and eliminate the need for prior knowledge of the target optical spectrum to adjust the chirp rate. |
| FILED | Tuesday, July 12, 2005 |
| APPL NO | 11/179765 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145798 | Witcraft et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | William F. Witcraft (Minneapolis, Minnesota); Lonny Berg (Elk River, Minnesota); Alan Hurst (Anoka, Minnesota); William Vavra (Maple Plain, Minnesota); Mark Jenson (Zimmerman, Minnesota) |
| ABSTRACT | An MRAM device comprising an array of MRAM elements, with each element having an MRAM bit influenced by a magnetic field from a current flowing through a conductor, also includes a magnetic keeper formed adjacent the conductor to advantageously alter the magnetic field. The magnetic keeper alters the magnetic field by concentrating the field within the keeper thereby reducing the extent in which fringe field exists, thus allowing the MRAM elements to be formed closer to increase the areal density of the MRAM device. Increase in magnetic field flux due to the magnetic keeper allows operation of the MRAM device with lowered power. Soft magnetic materials such as nickel iron, nickel iron cobalt, or cobalt iron may be used to form the magnetic keeper. |
| FILED | Thursday, May 19, 2005 |
| APPL NO | 11/132798 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145972 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Rajendra Kumar (Cerritos, California); Tien M. Nguyen (Fullerton, California) |
| ABSTRACT | A polyphase channelizer converts an intermediate frequency wideband signal into a complex signal that is sampled by parallel analog-to-digital converters having a bank of samplers respectively clocked by staggered clocking signals for respective converters for feeding I and Q quadrature samples to a polyphase filter bank of finite impulse response filters driving a fast Fourier transform processor for providing channelized digital signal outputs. The parallel analog-to-digital converters can operate at lower speeds but are parallel connected for effectively operating at required higher speeds. The channelizer channelizes the wideband signal using a polyphase clock for enabling high speed sampling and converting through low speed parallel analog to digital converters. |
| FILED | Thursday, October 18, 2001 |
| APPL NO | 09/982383 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/349 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07146282 | van der Weide et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Daniel W. van der Weide (Madison, Wisconsin); Charles A. Paulson (Clearlake, Minnesota); Thomas M. Grist (Madison, Wisconsin); Modhurin Banerjee (Madison, Wisconsin) |
| ABSTRACT | Localized magnetic fields are measured at frequencies into the microwave (GHz) regime using a conductive loop that is integrated on a vibratable member, such as a cantilever. Driving an alternating current at a first high frequency through the loop produces a high frequency alternating magnetic dipole at the same frequency as the current, with the alternating magnetic dipole normal to and centered within the loop. The alternating magnetic dipole at the center of the loop mixes with a sampled alternating magnetic field at a second high frequency at the center of the loop, resulting in application of a mechanical force to the loop and vibratable member. The vibratable member vibrates when the difference between the frequency of the loop current and the frequency of the sampled alternating magnetic field equals the resonant frequency of the vibratable member. |
| FILED | Friday, May 06, 2005 |
| APPL NO | 11/124599 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07146429 | Michel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Bartlett Scott Hudson Michel (Los Angeles, California) |
| ABSTRACT | Adaptive cooperative web caches construct and maintain routing and forwarding tables for efficient location of replicated web content data, thus reducing the time taken to fetch the requested web content data. The routing and forwarding tables in particular store decomposed web content identifiers and use compression techniques for efficient translation from a user request to the internet protocol address of the cache server where the replicated web content data can be retrieved. |
| FILED | Friday, March 16, 2001 |
| APPL NO | 09/810303 |
| ART UNIT | 2143 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/238 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 07144581 | Gaiger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Corixa Corporation (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Alexander Gaiger (Vienna, Austria); Martin A. Cheever (Mercer Island, Washington) |
| ABSTRACT | Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; or a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases. |
| FILED | Thursday, February 15, 2001 |
| APPL NO | 09/785019 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/277.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144616 | Unger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Marc A. Unger (South San Francisco, California); Hou-Pu Chou (Pasadena, California); Todd A. Thorsen (Pasadena, California); Axel Scherer (Laguna Beach, California); Stephen R. Quake (San Marino, California) |
| ABSTRACT | A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate. |
| FILED | Tuesday, November 28, 2000 |
| APPL NO | 09/724784 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144701 | Huang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Tim Hui-Ming Huang (Columbia, Missouri) |
| ABSTRACT | The present invention provides a method of hybridization, differential methylation hybridization (DMH) for high throughput methylation analysis of multiple CpG island loci. DMH utilizes nucleic acid probes prepared from a cell sample to screen numerous CpG dinucleotide rich fragments affixed on a screening array. Positive hybridization signals indicate the presence of methylated sites. Methods of preparing the hybridization probes and screening array are also provided. |
| FILED | Thursday, February 21, 2002 |
| APPL NO | 10/081327 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144708 | Janigro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Damir Janigro (Cleveland Heights, Ohio); Nicola Marchi (Cleveland, Ohio) |
| ABSTRACT | The present invention relates generally to a peripheral marker or markers of blood barrier integrity and methods of using same in the diagnosis, prognosis, and treatment of a variety of diseases. The peripheral marker(s) of the present invention are particularly useful in the differential diagnosis of diseased states. The preferred embodiments of the present invention relate to methods, compositions, kits, and assays useful in determining the integrity or permeability of either a blood CSF barrier or a blood brain barrier. The various embodiments of the present invention can be used to identify subjects at risk for developing a disease associated with increased permeability of the blood brain barrier, as well as to provide insight on the ability of an agent or agents to pass through the blood brain barrier. Embodiments of the present invention preferably involve the use of subject derived blood samples to determine the occurrence and level of circulating proteins indicative of blood brain barrier permeability or integrity. The embodiments of the present invention also provides screening methods for diagnosis, prognosis, susceptibility, or degree of permeability of penetration of the blood brain barrier by detecting the presence of serum Transthyretin either directly or through the use of antibodies. |
| FILED | Thursday, June 12, 2003 |
| APPL NO | 10/462222 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144710 | Guyre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Paul M. Guyre (Hanover, New Hampshire); Peter M. Morganelli (Sharon, Vermont); Nicholas J. Goulding (Harpenden, United Kingdom) |
| ABSTRACT | Methods for detecting the inflammatory biomarkers molecule CD 163 in biological samples are provided. Also provided are methods for monitoring the course of an inflammatory process or condition in a patient and compositions and methods for preventing and treating inflammation and inflammatory processes. |
| FILED | Tuesday, March 27, 2001 |
| APPL NO | 10/240382 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.940 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144712 | Milich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Vaccine Research Institute of San Diego (San Diego, California) |
| INVENTOR(S) | David R. Milich (Escondido, California); Jean-Noel Billaud (San Diego, California) |
| ABSTRACT | The present invention relates to hepatitis virus core proteins and nucleic acids. In particular, the present invention provides compositions and methods comprising recombinant hepatitis virus core proteins or nucleic acids for use in vaccine formulations. |
| FILED | Wednesday, July 30, 2003 |
| APPL NO | 10/630074 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144714 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Xiaodong Wang (Dallas, Texas); Qinghua Liu (Dallas, Texas) |
| ABSTRACT | Methods for making siRNA comprise recombinantly coexpressing a Dicer protein with an R2D2 protein to form a complex comprising the R2D2 protein and the Dicer protein, and contacting the complex with a double-stranded (ds) RNA under conditions wherein the complex cleaves the dsRNA into siRNA. The R2D2 protein may be a Drosophila R2D2 protein and the Dicer protein may be a Drosophila Dicer-2 protein. The Dicer protein and the R2D2 protein may be coexpressed in insect cells, such as S2, Sf9 or Hi5 cells, using a baculovirus expression system. |
| FILED | Thursday, September 25, 2003 |
| APPL NO | 10/670626 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144728 | Suciu-Foca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Nicole Suciu-Foca (New York, New York); Raffaello Cortesini (New York, New York); Zhuoru Liu (New York, New York); Chih-Chao Chang (Scarsdale, New York) |
| ABSTRACT | This invention also provides a method of generating antigen specific human suppressor CD8+CD28− T cells. This invention further provides a method of generating allopeptide antigen specific human suppressor CD8+CD28− T cells. Methods of tent for reduction of risk of rejection of allografts and xenografts and autoimmune diseases using the human suppressor CD8+CD28− T cells so produced are also provided, as are methods of preventing rejection and autoimmune diseases, and vaccines comprising the produced suppressor T cells. Methods of diagnosis to determine whether a level of immuno-suppressant therapy requires a reduction are provided. |
| FILED | Thursday, June 15, 2000 |
| APPL NO | 10/018677 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144732 | Ingham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Imperial Cancer Research Technology Institute (London, United Kingdom) |
| INVENTOR(S) | Philip W. Ingham (Oxford, United Kingdom); Andrew P. McMahon (Lexington, Massachusetts); Clifford J. Tabin (Cambridge, Massachusetts) |
| ABSTRACT | The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo. |
| FILED | Wednesday, April 28, 2004 |
| APPL NO | 10/835517 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144733 | Miesenböck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Gero Miesenböck (New York, New York); Boris V. Zemelman (New York, New York) |
| ABSTRACT | Cells are rendered sensitive to stimulation by introducing into a non-photoreceptor cell nucleic acid sequences encoding at least an opsin gene product, an arrestin gene product, and the alpha subunit of the heterotrimeric G protein of the Gq family. The introduced sequences are expressed by the cell to yield at least the opsin gene product, the arrestin gene product, and the alpha subunit of the heterotrimeric G protein of the Gq family. Retinal or a derivative thereof capable of bonding with the opsin gene product to form a rhodopsin is provided to the cell. The cell is then irradiated with light having a wavelength capable of converting the rhodopsin to metarhodopsin. The conversion of rhodopsin to metarhodopsin triggers a cascade of intracellular responses within the cell resulting in an increased intracellular concentration of IP3 and calcium ions. |
| FILED | Friday, August 16, 2002 |
| APPL NO | 10/222675 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144734 | Court et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Donald L. Court (Frederick, Maryland); Daiguan Yu (The Woodlands, Texas); E-Chiang Lee (The Woodlands, Texas); Hilary M. Ellis (San Ramon, California); Nancy A. Jenkins (Ijamsville, Maryland); Neal G. Copeland (Ijamsville, Maryland) |
| ABSTRACT | Disclosed herein are methods for generating recombinant DNA molecules in cells using homologous recombination mediated by recombinases and similar proteins. The methods promote high efficiency homologous recombination in bacterial cells, and in eukaryotic cells such as mammalian cells. The methods are useful for cloning, the generation of transgenic and knockout animals, and gene replacement. The methods are also useful for subcloning large DNA fragments without the need for restriction enzymes. The methods are also useful for repairing single or multiple base mutations to wild type or creating specific mutations in the genome. Also disclosed are bacterial strains and vectors which are useful for high-efficiency homologous recombination. |
| FILED | Wednesday, February 12, 2003 |
| APPL NO | 10/366044 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/471 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144858 | McCafferty |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Dewey G. McCafferty (Plymouth Meeting, Pennsylvania) |
| ABSTRACT | The present inventive subject matter relates to novel antibacterial compounds that are capable of inhibiting bacterial multiplication and killing living bacteria. The present inventive subject matter further relates to methods for treating Gram positive bacterial infections using the inventive compounds. |
| FILED | Monday, June 02, 2003 |
| APPL NO | 10/516012 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144860 | Ruoslahti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Erkki Ruoslahti (Rancho Santa Fe, California); Deidre A MacKenna (San Diego, California) |
| ABSTRACT | The present invention provides a heart homing peptide that contains the amino acid sequence GGGVFWQ (SEQ ID NO: 2); HGRVRPH (SEQ ID NO: 3); VVLVTSS (SEQ ID NO: 4); CLHRGNSC (SEQ ID NO: 9); or CRSWNKADNRSC (SEQ ID NO: 10) and further provides conjugates in which a heart homing peptide is linked to a moiety such as a therapeutic agent. The conjugates of the invention are useful for treating cardiovascular diseases such as atherosclerosis and restenosis. |
| FILED | Friday, July 20, 2001 |
| APPL NO | 09/910582 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144862 | Fogelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The University of Alabama Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Alan M. Fogelman (Beverly Hills, California); Gattadahalli M. Anantharamaiah (Birmingham, Alabama); Mohamad Navab (Los Angles, California) |
| ABSTRACT | This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. In certain embodiments, the peptide comprises an amino acid sequence that ranges in length from about 10 up to about 30 amino acids, that comprises at least one class A amphipathic helix, that bears at least one protecting group, that protects a phospholipid against oxidation by an oxidizing agent; and that is not the D-18A peptide. The peptides are highly stable and readily administered via an oral route. |
| FILED | Friday, June 28, 2002 |
| APPL NO | 10/187215 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144880 | Glick |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Gary D. Glick (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like. |
| FILED | Thursday, May 01, 2003 |
| APPL NO | 10/427212 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/212.70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144904 | Bergeron, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Raymond J. Bergeron, Jr. (Gainesville, Florida) |
| ABSTRACT | Composition, article of manufacture for and method of treating malaria in a human having an infestation of Plasmodium protozoans are described. The method comprises administering a therapeutically-effective amount of a compound of formula (I) or (IV), i.e. sufficient quantity to reduce the population of Plasmodium. The composition of the invention is a compound of formula (I) or (IV) with a pharmaceutical excipient. The article of manufacture is the composition in combination with labeling for treating malaria. The substituents are detailed in the specification. |
| FILED | Friday, November 19, 2004 |
| APPL NO | 10/993417 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/365 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144918 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michael R. Boyd (Mobile, Alabama); Kirk R. Gustafson (Frederick, Maryland); Charles L. Cantrell (Longmont, Colorado) |
| ABSTRACT | The present invention provides a compound of the formula (I). The present invention further provides a composition comprising at least one compound of the present invention and a pharmaceutically acceptable carrier, alone or in combination with at least one additional active agent. The present invention further provides a method of treating a condition treatable by the inhibition of vacuolar-type (H+)-ATPase and a method of treating cancer. |
| FILED | Tuesday, July 24, 2001 |
| APPL NO | 10/333710 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/449 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144950 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Goleta, California) |
| ABSTRACT | Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods. |
| FILED | Wednesday, September 17, 2003 |
| APPL NO | 10/666333 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/54.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144984 | Schimmel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Paul Schimmel (La Jolla, California); Keisuke Wakasugi (Shizuoka, Japan) |
| ABSTRACT | Compositions comprising tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed. |
| FILED | Wednesday, March 21, 2001 |
| APPL NO | 10/240527 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144986 | Saxinger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Carl Saxinger (Bethesda, Maryland) |
| ABSTRACT | The present invention provides, among other things, a polypeptide, and a pharmaceutically acceptable salt thereof, that inhibits the binding of IL-6 ligand with IL-6 receptor under physiological conditions, a nucleic acid that encodes such a polypeptide and can be expressed in a cell, a nucleic acid that comprises or encodes an antisense nucleic acid molecule or a ribozyme that is specific for such a polypeptide, an antibody that is specific to such a polypeptide, an anti-antibody thereto, a composition comprising such a polypeptide, nucleic acid, antibody or an anti-body and a carrier therefor, a composition comprising a solid support matrix to which is attached an above-described polypeptide or an anti-antibody to a specified polypeptide sequence, a method of prophylactically or therapeutically inhibiting IL-6 signaling in a mammal in need thereof, a mammal in need thereof, and a method of removing IL-6 ligand from a bodily fluid of an animal. |
| FILED | Wednesday, November 05, 2003 |
| APPL NO | 10/702765 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144989 | Acharya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Seetharama A. Acharya (Cresskill, New Jersey); Paul K. Smith (Roscoe, Illinois); Belur N. Manjula (Cresskill, New Jersey) |
| ABSTRACT | The present invention provides pegylated hemoglobins comprising a thiocarbamoyl-phenyl-polyethylene glycol (PEG) attached to hemoglobin, and comprising a polyethylene glycol (PEG) attached to hemoglobin by an acyl group. The invention also provides methods of preparing pegylated hemoglobins using isothiocyanato phenyl carbamate of PEG and using isothiocyanato phenyl di-PEG carbamate. The invention further provides compositions and blood substitutes comprising pegylated hemoglobins and methods of treating a subject which comprise administering to the subject blood substitutes comprising non-hypertensive pegylated hemoglobins. |
| FILED | Friday, October 01, 2004 |
| APPL NO | 10/957200 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/385 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145018 | White et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and through the State Board of Higher Education on behalf of the Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | James David White (Philomath, Oregon); Rich Garrett Carter (Oxford, Mississippi); Kurt Frederick Sundermann (Corvallis, Oregon) |
| ABSTRACT | A method for making epothilones and epothilone analogs is described, as are novel compounds made by the method. One embodiment of the method was used to synthesize epothilone B by a convergent approach that entailed Wittig coupling of an ylide derived from phosphonium bromide with an aldehyde. The former was prepared from propargyl alcohol by a nine-step pathway which installed both trisubstituted double bonds with clean Z configuration. Macrolactonization of a resulting seco acid provided the following intermediate diene epothilone analog. Selective saturation of the 9,10-olefin and subsequent epoxidation provided epothilone B |
| FILED | Thursday, May 05, 2005 |
| APPL NO | 11/123530 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/203 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145057 | Van de Lavoir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Origen Therapeutics, Inc. (Burlingame, California) |
| INVENTOR(S) | Marie-Cecile Van de Lavoir (San Francisco, California); Robert J. Etches (San Mateo, California); Babette Heyer (Menlo Park, California); Jennifer Diamond (Millbrae, California); Christine Mather (Millbrae, California); Kathleen Beemer (Pacifica, California); Heather Myers (Danville, California) |
| ABSTRACT | Sustained cultures of avian embryonic stem cells are provided. Injection of avian embryonic stem cells into recipient embryos yields chimeras with a significant contribution from the embryonic stem cell phenotype. Transgene encoding exogenous proteins are stably integrated in the embryonic stem cells and are present in the somatic tissue of the resulting chimeras. The transgenes may encode exogenous proteins expressed in endodermal, ectodermal, mesodermal, or extra embryonic tissue. Breeding the resulting chimera yields transgenic birds whose genome is comprised of exogenous DNA. |
| FILED | Friday, February 01, 2002 |
| APPL NO | 10/067148 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07146277 | Prestegard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | James H. Prestegard (Athens, Georgia) |
| INVENTOR(S) | James H. Prestegard (Watkinsville, Georgia); Nitin U. Jain (Athens, Georgia); Hashim M. Al-Hashimi (Athens, Georgia); Laura C. Morris (Auburn, Georgia); Andre P. Venot (Athens, Georgia) |
| ABSTRACT | Methods of using NMR spectroscopy for identifying ligands that bind to structurally uncharacterized proteins, and improving the binding affinity of ligands for biological targets are disclosed. One aspect of the method includes preparing first NMR spectra of a first complex comprising the biological target and a paramagnetically labeled derivative of a first ligand, preparing a second NMR spectra of a second complex comprising the biological target and a second ligand, and analyzing the spectra to determine whether the second ligand binds to the biological target within the paramagnetic zone of the paramagnetically labeled derivative. The first and second steps may be performed simultaneously, consecutively, or in any order. |
| FILED | Wednesday, June 13, 2001 |
| APPL NO | 09/880648 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07143785 | Maerkl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sebastian J. Maerkl (Pasadena, California); Todd A. Thorsen (Arlington, Massachusetts); Xiaoyan Bao (Pasadena, California); Stephen R. Quake (San Marino, California); Vincent Studer (Paris, France) |
| ABSTRACT | High-density microfluidic chips contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large scale integration (LSI). A component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. These integrated microfluidic networks can be used to construct a variety of highly complex microfluidic devices, for example the microfluidic analog of a comparator array, and a microfluidic memory storage device resembling electronic random access memories. |
| FILED | Wednesday, September 24, 2003 |
| APPL NO | 10/670997 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/597 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144563 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | Apparao M. Rao (Anderson, South Carolina); Nicholas W. Gothard (Central, South Carolina); Jay B. Gaillard (Clemson, South Carolina) |
| ABSTRACT | The present invention discloses a relatively simple CVD method for forming branched carbon nanotubes. In general, the method includes adding a dopant to the precursor materials. The dopant can be a material that has a thermodynamically more favorable carbide-forming reaction at the reactor conditions than does the catalyst that is provided to the reactor by a second precursor material. The doped nanoparticles formed in the reactor can adhere to the walls of the developing nanotubes and provide a nucleation site for the development of one or more branches on the nanotube. The nanotubes formed according to the invention can be recognized as such due to the presence of the doped nanoparticles adhered along the walls of the branched nanotubes. |
| FILED | Thursday, April 22, 2004 |
| APPL NO | 10/829660 |
| ART UNIT | 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144723 | Fenical et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William Fenical (Del Mar, California); Paul R. Jensen (San Diego, California); Tracy J. Mincer (San Diego, California) |
| ABSTRACT | The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors. |
| FILED | Friday, November 16, 2001 |
| APPL NO | 09/991518 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144753 | Swain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Greg M. Swain (East Lansing, Michigan); Yoshiyuki Show (East Lansing, Michigan); Prerna Sonthalia (East Lansing, Michigan); Malgorzata Witek (Baton Rouge, Louisiana) |
| ABSTRACT | A conductive boron doped nanocrystalline diamond is described. The boron doped diamond has a conductivity which uses the boron in the crystals as a charge carrier. The diamond is particularly useful for electrochemical electrodes in oxidation-reduction reactions and decontamination of aqueous solutions. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/991272 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144797 | Chow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Tat-Sing Paul Chow (Niskayuna, New York); Peter Losee (Clifton Park, New York); Santhosh Balachandran (Troy, New York) |
| ABSTRACT | A semiconductor device includes a graded junction termination extension. A method for fabricating the device includes providing a semiconductor layer having a pn junction, providing a mask layer adjacent to the semiconductor layer, etching the mask layer to form at least two laterally adjacent steps associated with different mask thicknesses and substantially planar step surfaces, and implanting a dopant species through the mask layer into a portion of the semiconductor layer adjacent to the termination of the pn junction. The semiconductor layer is annealed to activate at least a portion of the implanted dopant species to form the graded junction termination extension. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/949982 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/549 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144950 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Goleta, California) |
| ABSTRACT | Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods. |
| FILED | Wednesday, September 17, 2003 |
| APPL NO | 10/666333 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/54.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07146059 | Durand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Frédéric Durand (Boston, Massachusetts); Julie Dorsey (Arlington, Massachusetts) |
| ABSTRACT | A method of performing bilateral filtering and using the method for displaying high-dynamic-range images is presented. The method reduces the contrast of the image while preserving detail of the image. The presently disclosed method incorporates a two-scale decomposition of the image into a base layer encoding large-scale variations, and a detail layer. The base layer has its contrast reduced, thereby preserving detail. The base layer is obtained using an edge-preserving bilateral filter. The bilateral filter is a non-linear filter, where the weight of each pixel is computed using a Gaussian in the spatial domain multiplied by an influence function in the intensity domain that decreases the weight of pixels with large intensity differences. The bilateral filtering is accelerated by using a piecewise-linear approximation in the intensity domain and appropriate subsampling. |
| FILED | Wednesday, March 05, 2003 |
| APPL NO | 10/382174 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07145137 | Montaser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Akbar Montaser (Potomac, Maryland); Craig S. Westphal (Landenberg, Pennsylvania); Kaveh Kahen (Montgomery Village, Maryland); William F. Rutkowski (Arlington, Virginia); Billy W. Acon (Arlington, Virginia) |
| ABSTRACT | A nebulizer adapted for adjusting a position of a capillary tube contained within the nebulizer is provided. The nebulizer includes an elongated tubular shell having a gas input port and a gas output port, a capillary adjustment adapter for displacing the capillary tube in a lateral direction via a rotational force, and a connector for connecting the elongated tubular shell, the capillary adjustment adapter and the capillary tube. |
| FILED | Wednesday, December 22, 2004 |
| APPL NO | 11/019098 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145148 | Alfano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert R. Alfano (Bronx, New York); Baolong Yu (Bronx, New York) |
| ABSTRACT | The present invention provides systems and methods for non-destructively detecting material abnormalities beneath a coated surface. A terahertz (THz) illumination unit illuminates an area of the coated surface. A detection unit detects light reflected from the illuminated area of the coated surface, and a processing unit images the illuminated area of the coated surface from optical characteristics received from the detection unit. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/949571 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145149 | Cooke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | D. Wayne Cooke (Santa Fe, New Mexico); Bryan L. Bennett (Los Alamos, New Mexico); Ross E. Muenchausen (Los Alamos, New Mexico); Debra A. Wrobleski (Los Alamos, New Mexico); Edward B. Orler (Los Alamos, New Mexico) |
| ABSTRACT | A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. The binder is transparent to the scintillator emission. The composite is seamless and can be made large and in a wide variety of shapes. Importantly, the composite can be tailored to emit light in a spectral region that matches the optimum response of photomultipliers (about 400 nanometers) or photodiodes (about 600 nanometers), which maximizes the overall detector efficiency. |
| FILED | Tuesday, September 21, 2004 |
| APPL NO | 10/946025 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/361.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145229 | Maghribi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mariam N. Maghribi (Livermore, California); Peter Krulevitch (Pleasanton, California); Julie Hamilton (Tracy, California) |
| ABSTRACT | A system for providing metal features on silicone comprising providing a silicone layer on a matrix and providing a metal layer on the silicone layer. An electronic apparatus can be produced by the system. The electronic apparatus comprises a silicone body and metal features on the silicone body that provide an electronic device. |
| FILED | Thursday, November 14, 2002 |
| APPL NO | 10/295096 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/702 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145268 | Edwards et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | John Edwards (Kent, Washington); Longya Xu (Columbus, Ohio); Brij B. Bhargava (Santa Barbara, California) |
| ABSTRACT | A method for driving a neutral point clamped three-level inverter is provided. In one exemplary embodiment, DC current is received at a neutral point-clamped three-level inverter. The inverter has a plurality of nodes including first, second and third output nodes. The inverter also has a plurality of switches. Faults are checked for in the inverter and predetermined switches are automatically activated responsive to a detected fault such that three-phase electrical power is provided at the output nodes. |
| FILED | Tuesday, December 31, 2002 |
| APPL NO | 10/335683 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical transmission or interconnection systems 37/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07146221 | Krulevitch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter Krulevitch (Pleasanton, California); Dennis L. Polla (Roseville, Minnesota); Mariam N. Maghribi (Davis, California); Julie Hamilton (Tracy, California) |
| ABSTRACT | An image is captured or otherwise converted into a signal in an artificial vision system. The signal is transmitted to the retina utilizing an implant. The implant consists of a polymer substrate made of a compliant material such as poly(dimethylsiloxane) or PDMS. The polymer substrate is conformable to the shape of the retina. Electrodes and conductive leads are embedded in the polymer substrate. The conductive leads and the electrodes transmit the signal representing the image to the cells in the retina. The signal representing the image stimulates cells in the retina. |
| FILED | Friday, November 16, 2001 |
| APPL NO | 09/992248 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07144580 | Confer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| INVENTOR(S) | Anthony W. Confer (Stillwater, Oklahoma); Sahlu Ayalew (Stillwater, Oklahoma); George L. Murphy (Austin, Texas); Karamjeet Pandher (Ft. Collins, Colorado) |
| ABSTRACT | Vaccines and methods against M. haemolytica infections in cattle. The vaccine compositions include a recombinant outer membrane protein of M. haemolytica designated PlpE and/or subunits thereof, alone or in combination with other antigenic components, and a carrier or diluent. The methods involve administering an effective immunizing amount of the vaccines to susceptible bovine. |
| FILED | Tuesday, September 27, 2005 |
| APPL NO | 11/235982 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/255.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144753 | Swain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Greg M. Swain (East Lansing, Michigan); Yoshiyuki Show (East Lansing, Michigan); Prerna Sonthalia (East Lansing, Michigan); Malgorzata Witek (Baton Rouge, Louisiana) |
| ABSTRACT | A conductive boron doped nanocrystalline diamond is described. The boron doped diamond has a conductivity which uses the boron in the crystals as a charge carrier. The diamond is particularly useful for electrochemical electrodes in oxidation-reduction reactions and decontamination of aqueous solutions. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/991272 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07145611 | Dubin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Matthew B. Dubin (Scottsdale, Arizona); Brent D. Larson (Cave Creek, Arizona); Aleksandra Kolosowsky (Phoenix, Arizona) |
| ABSTRACT | A modular and scalable seamless tiled display apparatus includes multiple display devices, a screen, and multiple lens assemblies. Each display device is subdivided into multiple sections, and each section is configured to display a sectional image. One of the lens assemblies is optically coupled to each of the sections of each of the display devices to project the sectional image displayed on that section onto the screen. The multiple lens assemblies are configured to merge the projected sectional images to form a single tiled image. The projected sectional images may be merged on the screen by magnifying and shifting the images in an appropriate manner. The magnification and shifting of these images eliminates any visual effect on the tiled display that may result from dead-band regions defined between each pair of adjacent sections on each display device, and due to gaps between multiple display devices. |
| FILED | Friday, December 22, 2000 |
| APPL NO | 09/746739 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Liquid crystal cells, elements and systems 349/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145739 | Bly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Vincent T. Bly (Springfield, Virginia) |
| ABSTRACT | This invention is directed to a process for manufacturing a lightweight mirror from a single crystal material, such as single crystal silicon. As a near perfect single crystal material, single crystal silicon has much lower internal stress than a conventional material. This means much less distortion of the optical surface during the light weighting process. After being ground and polished, a single crystal silicon mirror is light weighted by removing material from the back side using ultrasonic machining. After the light weighting process, the single crystal silicon mirror may be used as-is or further figured by conventional polishing or ion milling, depending on the application and the operating wavelength. |
| FILED | Thursday, March 06, 2003 |
| APPL NO | 10/385166 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 07145496 | Cho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kwang M. Cho (Rancho Palos Verdes, California); Leo H. Hui (Alhambra, California) |
| ABSTRACT | A radar on a moving platform generates an initial synthetic aperture (SAR) image of a scene from a sequence of periodic pulse returns approximately motion compensated. The SAR image is formed from pixel intensities zn(x,y) within a x,y extent of the initial synthetic aperture image. Targets are selected from the initial synthetic aperture image using a sliding window, computing a first entropy for the selected targets, and sorting the targets using the first entropy to obtain a target list having target elements, then concatenating the target elements to form a data matrix compatible in the azimuth dimension with a Fast Fourier Transform. A phase correction for autofocus is iteratively computed and applied to the initial synthetic aperture image using an inner loop, a mid loop and an outer loop. The phase correction is expressed using an orthogonal polynomial having a plurality n consecutive terms an, a2 denoting a quadratic term, and aN denoting a last order term. The outer loop, using an L index, calculates an outer loop EL(a2) entropy for the quadratic term and an outer loop EL(aN) entropy for the last order term. Iterations within the outer loop continue until EL(a2)−EL(aN) is less than an outer loop tolerance. Similarly, the mid loop, and inner loop continue until the computation of their respective entropies meet a pre-set tolerance. The inner loop entropy uses a Golden Section search for computing the inner loop entropy. |
| FILED | Tuesday, November 23, 2004 |
| APPL NO | 10/996246 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07145498 | Cho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kwang M. Cho (Los Angeles, California); Leo H. Hui (Alhambra, California) |
| ABSTRACT | A moving radar generates a search mode synthetic aperture image of a patch from periodic pulse returns reflected from the patch. The patch is imaged from radar returns derived from two or more overlapping arrays. A strong scatterer is located within each array, then the data from each array is motion compensated with respect to the motion of the radar and the strong scatterer. The motion compensated results for each array are autofocused to derive a phase error for each array. Using the phase error for each array, a connected phase error estimate is computed, added to the phase error of each array to minimize the differences between phases in the overlap between arrays insuring that there is no or minimal phase discontinuity in the overlap region between arrays. Avoiding phase discontinuity yields a clear SAR image of the combination of arrays rendering the patch. |
| FILED | Wednesday, August 10, 2005 |
| APPL NO | 11/200836 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07144544 | Bulluck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Texas Research International, Inc. (Austin, Texas) |
| INVENTOR(S) | John W. Bulluck (Spicewood, Texas); Brad A. Rix (Spicewood, Texas) |
| ABSTRACT | An ultraviolet (UV) light curable formulation useful for repairing composite materials, comprising: an acrylic oligomer, an acrylic monomer, and a photoinitiator. This formulation may include fiberglass. The photoinitiator can be a combination of a bis-acylphosphine oxide and an alpha hydroxy ketone. The formulation can cure rapidly, such as in about 20 minutes. The cured formulation can have a Tg above 150° C. |
| FILED | Friday, February 20, 2004 |
| APPL NO | 10/784002 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07144581 | Gaiger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Corixa Corporation (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Alexander Gaiger (Vienna, Austria); Martin A. Cheever (Mercer Island, Washington) |
| ABSTRACT | Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; or a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases. |
| FILED | Thursday, February 15, 2001 |
| APPL NO | 09/785019 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/277.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07143637 | McBrearty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael McBrearty (Hockessin, Delaware); Anthony J. Bur (Rockville, Maryland) |
| ABSTRACT | The dielectric slit die is an instrument that is designed to measure electrical, rheological, ultrasonics, optical and other properties of a flowing liquid. In one application, it is connected to the exit of an extruder, pump or mixing machine that passes liquefied material such as molten plastic, solvents, slurries, colloidal suspensions, and foodstuffs into the sensing region of the slit shaped die. Dielectric sensing is the primary element of the slit die, but in addition to the dielectric sensor, the die contains other sensing devices such as pressure, optical fiber, and ultrasonic sensors that simultaneously yield an array of materials property data. The slit die has a flexible design that permits interchangeability among sensors and sensor positions. The design also allows for the placement of additional sensors and instrumentation ports that expand the potential data package obtained. |
| FILED | Thursday, April 08, 2004 |
| APPL NO | 10/820956 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/53.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07144865 | Song |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Moon K. Song (Northridge, California) |
| ABSTRACT | The present invention relates to dietary supplementing methods useful for controlling obesity. More particularly, the invention relates to methods of administration of compositions containing defined chemical species useful for prevention and treatment of obesity. In a preferred embodiment, pharmaceutical compositions used in connection with the present invention comprise: (1) a zinc salt, (2) cyclo-Hispro and/or (3) arachidonic acid, and (4) at least one pharmaceutically acceptable excipient. More particularly, the invention relates to methods of manufacturing of preparing a soybean protein hydrolysate (SPH) comprising cyclo-Hispro. |
| FILED | Friday, January 30, 2004 |
| APPL NO | 10/768200 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07145018 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and through the State Board of Higher Education on behalf of the Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | James David White (Philomath, Oregon); Rich Garrett Carter (Oxford, Mississippi); Kurt Frederick Sundermann (Corvallis, Oregon) |
| ABSTRACT | A method for making epothilones and epothilone analogs is described, as are novel compounds made by the method. One embodiment of the method was used to synthesize epothilone B by a convergent approach that entailed Wittig coupling of an ylide derived from phosphonium bromide with an aldehyde. The former was prepared from propargyl alcohol by a nine-step pathway which installed both trisubstituted double bonds with clean Z configuration. Macrolactonization of a resulting seco acid provided the following intermediate diene epothilone analog. Selective saturation of the 9,10-olefin and subsequent epoxidation provided epothilone B |
| FILED | Thursday, May 05, 2005 |
| APPL NO | 11/123530 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/203 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07143937 | Rainey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Brent A. Rainey (Sterling, Virginia); Daryl S. Hamilton (Hyattsville, Maryland); Anthony M. Ferlaino (Fairfax, Virginia) |
| ABSTRACT | Collecting a label in an item delivery system (100) comprises reading a label on a unit load when the unit load is terminated, defacing the label if the quality of the label meets a predefined quality level, depositing the label in a read bin holder if the quality of the label meets a predetermined quality level, and depositing the label in a no-read bin holder if the quality of the label does not meet a predefined quality level. The item delivery system includes a network (160) facilitating communication between an information system (110), a label collection system (120), legacy systems (130), customer systems (140), and delivery systems (150). |
| FILED | Thursday, February 21, 2002 |
| APPL NO | 10/468482 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Registers 235/383 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07145333 | Romalis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Michael Romalis (Princeton, New Jersey); Tom Kornack (Princeton Junction, New Jersey); Joel Allred (Seattle, Washington); Rob Lyman (Charlottesville, Virginia) |
| ABSTRACT | The present invention provides a high sensitivity atomic magnetometer and methods of measuring low intensity magnetic fields that relate to the use of an alkali metal vapor and a buffer gas; increasing the magnetic polarization of the alkali metal vapor thereby increasing the sensitivity of the alkali metal vapor to a low intensity magnetic field; probing the magnetic polarization of the alkali metal vapor, the probing means providing an output from the alkali metal vapor, the output including characteristics related to the low intensity magnetic field; and measuring means that receives the output, determines the characteristics of the low intensity magnetic field, and provides a representation of the low intensity magnetic field. In addition, the invention relates to a magnetometer and methods that provide a representation of a first magnetic field originating within a sample volume. The sample volume may be part or all of a subject, such as a human subject. The representation includes a representation of a source of a magnetic field occurring within the sample volume displayed in one, two, or three of three orthogonal Cartesian coordinates, referenced to the sample volume. |
| FILED | Monday, May 23, 2005 |
| APPL NO | 11/135853 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/304 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 05, 2006.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20061205.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page