FedInvent™ Patents

Patent Details for Tuesday, February 20, 2007 

This page was updated on Sunday, March 26, 2023 at 08:40 PM GMT

Department of Defense (DOD) 

US 07178384 Bujas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) General Atomics (San Diego, California)
INVENTOR(S) Roko S. Bujas (Leucadia, California);  Ralf Dunkel (San Diego, California)
ABSTRACT Method and apparatus for testing ultralow moisture permeation through a sample such as a thin barrier film by exposing one surface of a sample to be tested for moisture permeation to a predetermined humidity of HTO. The HTO permeating therethrough is collected in a stream of dry gas, preferably methane, at a known very slow flow rate, and monitored for its radioactivity content. By very carefully sizing the respective chambers, continuously monitoring using a particularly sensitive device and appropriately converting the signals, accurate assessment of permeation rates even as low as very small fractions of a gram of water per square meter per day can be obtained. Ultralow oxygen permeation is alternatively measured using 14CO. Methods are also shown for measuring permeation that would occur through a perimeter seal and for measuring permeation which would result from gaseous entry into edge surfaces of a composite film.
FILED Wednesday, February 04, 2004
APPL NO 10/772765
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/38
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US 07178782 York
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Matthew E. York (Sewell, New Jersey)
ABSTRACT A valve uniquely integrates ball valve and throttling valve principals, thus affording quieter stop-and-start operation. A ball held by two seat rings is rotatable ninety degrees and has a diametric bore adjustable between fully closed (0°) and fully open (90°) positions. Oppositely disposed, relative to both the ball and the valve's longitudinal axis, are two plate assemblies each describing a tortuous fluid path. Each ring has conduits communicating with an assembly's tortuous path and communicable with the bore so that, sequentially during the ball's 0° to 90° rotation: the ball seals off the conduits, no fluid passing through the valve; all fluid passing through the valve flows through the plate assemblies and conduits; some fluid passing through the valve flows through the plate assemblies and conduits, some fluid passing through the valve flowing freely; the ball seals off the conduits, all fluid passing through the valve flowing freely.
FILED Friday, May 23, 2003
APPL NO 10/443825
ART UNIT 3751 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Valves and valve actuation
251/127
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US 07179054 Borges
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Guy F. Borges (Somerset, Massachusetts)
ABSTRACT An axial fan has a blade support wheel coupled to a drive shaft. A disk is positioned about the drive shaft adjacent the wheel. A torsion spring is coupled to the wheel and to the disk. When the torsion spring is in tension, the disk is poised for a relative rotation about the drive shaft. A lock couples the disk to the wheel when the torsion spring is in tension. Fan blades are supported by the wheel, and are coupled to the disk. Rotation of the drive shaft rotates the fan blades generating a specific flow direction. To reverse the flow direction, a release mechanism uncouples the lock from the disk and wheel causing the disk to experience rotation about the drive shaft as tension in the torsion spring is released. The disk's relative rotation re-positions the fan blades reversing the flow direction as the drive shaft continues to rotate.
FILED Friday, May 14, 2004
APPL NO 10/847681
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/31
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US 07179090 Lynch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) William A. Lynch (Philadelphia, Pennsylvania);  Neal A. Sondergaard (Severna Park, Maryland)
ABSTRACT A dual-nature, uni-constructed device, suitable for conducting electricity between two objects in relative motion, comprises two compatible elements each having a straight section and a sinuous section. The two elements are combined to form a unified whole whereby the two straight sections are mutually servable as a brush component and the two sinuous sections are mutually servable as a spring component. The inventive device is associable with an electrical or electromechanical machine so that, during machine operation, the brush component slidingly contacts a first machine part, the spring component is affixed to a second machine part and exerts a bias against the brush component, and the inventive device conducts electrical current from one machine part to the other machine part. Each element includes an electrically conductive main layer (including one or more wire fabric sheets) and two elastomeric outside layers (on opposite sides of the sinuous section).
FILED Thursday, December 08, 2005
APPL NO 11/311576
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrical connectors
439/13
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US 07179145 Driscoll et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Florida Atlantic Avenue (Boca Raton, Florida)
INVENTOR(S) Frederick R. Driscoll (Pembroke Pines, Florida);  Thomas A. Pantelakis (Coral Springs, Florida);  Christophe Castanier (Corbeil Essonnes, France);  William A. Venezia (Boca Raton, Florida)
ABSTRACT A self-mooring module. In particular, a self-mooring module that may be deployed by air, surface or underwater. The module includes a combination anchor/air brake, a buoy, and a mooring line. The module may also include a sensor module. The anchor, combination anchor/air brake and buoy may be used in combination as part of the module or may be used alone in different aspects. The anchor and combination anchor/air brake are foldable to conserve space. The buoy has reduced drag and increased stability versus regular buoys. The self-mooring module may also include an intelligent mooring line module that determines the amount of mooring line to be released for a particular mooring depth and does not release a substantive amount of extra or insufficient mooring line, thereby helping ensure proper placement of an sensor module. Other features include a release mechanism for releasing the anchor from the module and a mechanism for inflating the buoy.
FILED Thursday, February 05, 2004
APPL NO 10/772479
ART UNIT 3617 — Electrical Circuits and Systems
CURRENT CPC
Buoys, rafts, and aquatic devices
441/7
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US 07179356 Aksay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Ilhan A. Aksay (Princeton, New Jersey);  Mathias Trau (Balmosal, Australia);  Srinivas Manne (Tucson, Arizona);  Itaru Honma (Chiba, Japan);  George Whitesides (Newton, Massachusetts)
ABSTRACT A process directed to preparing surfactant-polycrystalline inorganic nanostructured materials having designed microscopic patterns. The process includes forming a polycrystalline inorganic substrate having a flat surface and placing in contact with the flat surface of the substrate a surface having a predetermined microscopic pattern. An acidified aqueous reacting solution is then placed in contact with an edge of the surface having the predetermined microscopic pattern. The solution wicks into the microscopic pattern by capillary action. The reacting solution has an effective amount of a silica source and an effective amount of a surfactant to produce a mesoscopic silica film upon contact of the reacting solution with the flat surface of the polycrystalline inorganic substrate and absorption of the surfactant into the surface. Subsequently an electric field is applied tangentially directed to the surface within the microscopic pattern. The electric field is sufficient to cause electro-osmotic fluid motion and enhanced rates of fossilization by localized Joule heating.
FILED Friday, April 11, 2003
APPL NO 10/411641
ART UNIT 1753 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical and wave energy
24/450
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US 07179509 Kornfield et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Julia A. Kornfield (Pasadena, California);  Michael D. Kempe (Pasadena, California)
ABSTRACT An electro-optically active polymer gel material comprising a high molecular weight alignment polymer adapted to be homogeneously dispersed throughout a liquid crystal to control the alignment of the liquid crystal molecules and/or confer mechanical stability is provided. The electro-optically active polymer gel comprises a homogenous gel in which the polymer strands of the gel are provided in low concentration and are well solvated by the small molecule liquid crystal without producing unacceptable slowing of its electrooptic response. During formation of the gel, a desired orientation is locked into the gel by physical or chemical cross-linking of the polymer chains. The electro-optically active polymer is then utilized to direct the orientation in the liquid crystal gel in the “field off” state of a liquid crystal display. The electro-optically active polymer also provides a memory of the mesostructural arrangement of the liquid crystal and acts to suppress the formation of large scale deviations, such as, for example, fan-type defects in a FLC when subjected to a mechanical shock. A method of making an electro-optically active polymer gel material and an electrooptic device utilizing the electro-optically active polymer gel of the present invention is also provided.
FILED Monday, January 12, 2004
APPL NO 10/755906
ART UNIT 1756 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Stock material or miscellaneous articles
428/1.100
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US 07179543 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey);  Universal Display Corporation (Ewing, New Jersey)
INVENTOR(S) Stephen R. Forrest (Princeton, New Jersey);  Brian Wendell D'Andrade (Princeton, New Jersey);  Anna Chwang (Princeton, New Jersey)
ABSTRACT The present invention is directed to multi-layer organic devices having improved stability, wherein at least one layer of the device comprises a host material that is morphologically unstable and a dopant material that provides improved morphological properties to the layer. The layer may be incorporated into, for example, OLEDs, organic phototransistors, organic photovoltaic cells, and organic photodetectors.
FILED Monday, October 06, 2003
APPL NO 10/680065
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Stock material or miscellaneous articles
428/690
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US 07179587 van der Weide
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Daniel W. van der Weide (Madison, Wisconsin)
ABSTRACT High frequency interfacing to biochemical membranes, such as supported bilayers and cell membranes, is carried out by supporting a biochemical membrane on a support surface while allowing access to the surface of the membrane through an opening in the support. A sharp tipped probe is positioned adjacent to the exposed surface of the membrane. The probe may have an inner core tip and a coaxial shield around the core tip that is electrically insulated therefrom. Radio frequency power is supplied to the probe to apply a localized radio frequency field to the membrane adjacent to the probe. Transport and binding events at the membrane are detected by changes in the field transmitted through the membrane and received by a receiving probe, or reflected from the membrane and received by the transmitting probe, and coupled therefrom to a detector for detection.
FILED Wednesday, November 27, 2002
APPL NO 10/306849
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
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US 07179797 McNeel
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Douglas McNeel (Madison, Wisconsin)
ABSTRACT A DNA vaccine for the treatment of prostate cancer, comprising a plasmid vector comprising a nucleotide sequence encoding prostatic acid phosphatase (PAP) operably linked to a transcription regulatory element, wherein upon administration to a mammal a cytotoxic immune reaction against cells expressing PAP is induced. In preferred embodiment, the PAP encoded is a xenoantigen highly homologous to the autoantigen PAP of the mammal. Also disclosed are methods for inducing prostatitis, or inducing immune reaction to PAP, or treating prostate cancer in a mammal, using the DNA vaccine and pharmaceutical compositions comprising the vaccine. Preferably, xenoantigen vaccination is followed by boosting with autoantigen PAP from the same animal species as the mammal being treated.
FILED Thursday, September 25, 2003
APPL NO 10/669474
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07179894 Gorenstein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) David G. Gorenstein (Houston, Texas);  David J. King (Galveston, Texas);  Daniel A. Ventura (Galveston, Texas);  Allan R. Brasier (Galveston, Texas)
ABSTRACT A random combinatorial selection method is disclosed for the construction of oligonucleotide aptamers in which nuclease resistance is conferred by the inclusion of modified nucleotides. The modified nucleotides are incorporated during PCR amplification to form achiral modified oligonucleotides. Thio-substituted aptamers are provided that bind tightly to the nuclear factor for human IL6 (NF-IL6).
FILED Thursday, April 11, 2002
APPL NO 10/120815
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
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US 07179923 Benson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) Karl E. Benson (St. Paul, Minnesota);  Moses M. David (Woodbury, Minnesota);  Cary A. Kipke (Woodbury, Minnesota);  Brinda B. Lakshmi (Woodbury, Minnesota);  Charles M. Leir (Falcon Heights, Minnesota);  George G. I. Moore (Afton, Minnesota);  Rahul R. Shah (Woodbury, Minnesota)
ABSTRACT Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonylaminocarbonyl group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a carbonylimino-containing connector group. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.
FILED Friday, November 12, 2004
APPL NO 10/987522
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/210
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US 07179986 Harman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Theodore C. Harman (Lexington, Massachusetts);  Patrick J. Taylor (Woburn, Massachusetts);  Michael P. Walsh (Lunenburg, Massachusetts);  Brian E. LaForge (Tyngsboro, Massachusetts)
ABSTRACT A thermoelectric (TE) device includes a first leg of TE material (a pseudobinary or pseudoternary alloy) and a second leg comprising a metal wire. The second leg is in thermal and electrical communication with the first leg. The TE device has a ZT value of approximately 2.0 at a temperature of approximately 300K.
FILED Thursday, May 08, 2003
APPL NO 10/431747
ART UNIT 1753 — Organic Chemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/200
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US 07180066 Qiu
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Chang-Hua Qiu (Plainsboro, New Jersey)
ABSTRACT A quantum-well infrared photodetector (QWIP) is presented. The photodetector includes a substrate, a buffer layer, a first conductive layer, a multiple quantum well, an optional blocking layer, and a second conductive layer. Substrate is composed of a monocrystal which may be removed after fabrication. Remaining layers are composed of group III-V nitrides, including binary, ternary, and quaternary compositions. Alternate embodiments of the present invention include a doped binary alloy along first and second conductive layers, a binary alloy along buffer and blocking layers, and alternating alloys of binary, ternary and quaternary compositions within the multiple quantum well. The present invention responds to infrared light at normal and oblique incidences, from near infrared to very far infrared.
FILED Wednesday, November 24, 2004
APPL NO 10/996766
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/338.400
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US 07180242 Rostoker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Norman Rostoker (Irvine, California);  Michl Binderbauer (Irvine, California);  Artan Qerushi (Irvine, California);  Hooshang Tahsiri (Irvine, California)
ABSTRACT A system and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions they are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels.
FILED Thursday, May 19, 2005
APPL NO 11/134776
ART UNIT 2821 — Electrical Circuits and Systems
CURRENT CPC
Electric lamp and discharge devices: Systems
315/111.210
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US 07180301 Hynes
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The Untied States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Mark W. Hynes (Sierra Vista, Arizona)
ABSTRACT A device for sensing and capturing the state of a direct current electrical power line comprising a voltage comparator having a pair of inputs, one of the inputs adapted to be connected to the power line, the other input connected to an analog and digital I/O module for supplying a threshold voltage to the voltage comparator, a plurality of latches, an equal plurality of integrators having different time constants, each integrator connected between the output of the voltage comparator and one of the plurality of latches for supplying an integrated replica of the output from the comparator to the latch, the analog and digital I/O module also being connected to the plurality of latches for reading the states of the respective latches and for resetting any set latch, and a programmed computer connected to the analog and digital I/O module for controlling the operation of the analog and digital module and for logging the occurrence of the setting of a latch.
FILED Wednesday, November 30, 2005
APPL NO 11/296709
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/522
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US 07180416 Amidon
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Charles Philip Amidon (Portsmouth, Rhode Island)
ABSTRACT A method and apparatus is described for enabling a single sensor to indicate a greater quantity of information about a sensed event, or the occurrence of many different types of events. A sensor system employs a number of individual sensors with single-use indication means (such as an explosive charge). Each individual sensor is equipped with a chronometer. The sensors are programmed to transmit information through their single-use indication means at specific times with each specific time being indicative of a particular type of event or of specific information about an event. A central monitor chronologically records all sensor indications and compares indication times to a schedule of time keyed information to determine the nature of each sensor indication.
FILED Wednesday, March 02, 2005
APPL NO 11/076831
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/539.220
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US 07180442 Nguyen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thach N. Nguyen (Waldorf, Maryland)
ABSTRACT A method of identifying an unknown target comprising creating a density function of cepstral coefficients for a known target; receiving a signal from the unknown target; transforming the signal from a time spectrum to a frequency spectrum using a Fourier transform; transforming the frequency spectrum to a cepstrum; creating a density function of cepstral coefficients for the unknown target; and comparing the density function of the unknown target with the density function of the known target.
FILED Wednesday, May 03, 2006
APPL NO 11/434573
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/90
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US 07180457 Trott et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Keith D. Trott (Shrewsbury, Massachusetts);  Joseph P. Biondi (Townsend, Massachusetts);  Ronni J. Cavener (Andover, Massachusetts);  Robert V. Cummings (Marlborough, Massachusetts);  James M. McGuinnis (Salem, New Hampshire);  Thomas V. Sikina (Acton, Massachusetts);  Erdem A. Yurteri (Lawrence, Massachusetts);  Fernando Beltran (Mashpee, Massachusetts)
ABSTRACT A radiator element includes a pair of substrates each having a transition section and a feed surface, each of the substrates is spaced apart from one another. The radiator element further includes a balanced symmetrical feed having a pair of radio frequency (RF) feed lines disposed adjacent to and electromagnetically coupled to the feed surface of one of a corresponding one of the pair of transition sections, and the pair of radio frequency feed lines forms a signal null point adjacent the transition sections.
FILED Friday, July 11, 2003
APPL NO 10/617620
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/770
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US 07180581 Shan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jerry W. Shan (Raritan, New Jersey);  Paisan Atsavapranee (Cabin John, Maryland)
ABSTRACT An illuminator (e.g., laser) produces a light beam that partially passes through, and is partially blocked by, a mask contrastingly patterned via non-transparent and transparent portions. The mask-conformed light passes through a lens so that the mask's pattern is projected into fluid seeded with a luminescent substance, which illuminatively reveals an image of the mask's pattern. The light beam can also be expanded and/or diffused prior to reaching the mask. Instead of or in addition to transmissive properties, the mask can have reflective properties wherein the illuminator-produced light beam partially bounces off of, and is partially absorbed by, a mask contrastingly patterned via non-reflective and reflective portions. Reflective optics can supplement or replace refractive optics for projecting the mask's pattern into the fluid. Indication of fluid flow and/or fluid concentration change is afforded through perceived distinctions between the illuminatively revealed images obtained at the same location at different times.
FILED Thursday, September 02, 2004
APPL NO 10/932647
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/28.500
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US 07180598 Willig et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Reinhardt L. Willig (Maynard, Massachusetts);  William P. Kelleher (Acton, Massachusetts);  Stephen P. Smith (Medford, Massachusetts)
ABSTRACT A photonic crystal interferometric optical gyroscope system including a light source for providing a primary beam of light, a photonic crystal sensing coil having a rotational axis, and a beam controlling device configured to split the primary beam into first and second counter-propagating beams in the photonic crystal sensing coil and configured to direct return of the counter-propagating beams wherein the power of the returning counter-propagating beams represents the phase shift between the counter-propagating beams and is indicative of the rate of rotation of the coil about the rotational axis.
FILED Thursday, November 13, 2003
APPL NO 10/712702
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/460
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US 07180751 Geschke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) Isothermal Systems Research, Inc. (Liberty Lake, Washington)
INVENTOR(S) Gregory S. Geschke (Spokane, Washington);  William C. Gustafson (Moscow, Idaho);  Alan B. Roberts (Moscow, Idaho)
ABSTRACT An input/output transition board system for collecting and distributing input/output signals between a backplane board and an I/O board while allowing for additional electronic devices. The input/output transition board system includes a transition board having at least one front connector and at least one rear connector. The front connector is connectable to a corresponding rear panel connector within a backplane board. The rear connector is connectable to a corresponding front I/O connector of an I/O board. The transition board collects and passes the signals between the I/O board and the backplane board. The transition board is also preferably active with additional electronic devices connected to the transition board.
FILED Thursday, February 19, 2004
APPL NO 10/783397
ART UNIT 2841 — Optics
CURRENT CPC
Electricity: Electrical systems and devices
361/788
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US 07180828 Sommer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Keith E. Sommer (Satellite Beach, Florida);  Henry P. Stottmeister (Rockville, Maryland)
ABSTRACT A hydrophone stave comprises a tubular member, a braided cord (or similar flexible structure), cylindrical hydrophones, pins, two plugs and two couplings. The hose (made of a thermoplastic material) is corrugated or convoluted, and is cuffed at both ends to permit a plug to engage at each end. Each coupling includes a wire rope (or similar flexible structure). Each hydrophone has a longitudinal through-aperture (through which the braided cord passes) and a perpendicularly transverse through-aperture (through which a pin passes while also passing through a void created between strands of the braided cord). The stave is suitable for incorporation into a hydrophone array assembly providing for a selected arrayal of hydrophones, e.g., an assembly including two opposite frames united therebetween by numerous congruous parallel staves, each stave including equally spaced hydrophones, each coupling linking a plug with a frame so that the staves are selectively arranged.
FILED Thursday, April 22, 2004
APPL NO 10/829615
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/154
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181015 Matt
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) McAfee, Inc. (Santa Clara, California)
INVENTOR(S) Brian J. Matt (Riva, Maryland)
ABSTRACT One embodiment of the present invention provides a system for establishing a shared cryptographic key between participating nodes in a network. The system operates by sending a first message from the first node to the second node requesting establishment of a shared key. The second node sends a second message containing identifiers and a message authentication code to a key distribution center (KDC). The authentication code is generated using a second node key belonging to the second node. The KDC recreates the previously created second node key using the second node identifier and a secret key known only to the key distribution center. The KDC then verifies the message authentication code using the second node key. If the message authentication code is verified, the KDC creates a shared key for the nodes to use while communicating with each other. The KDC securely communicates this shared key to the participating nodes
FILED Tuesday, July 31, 2001
APPL NO 09/921231
ART UNIT 2137 — Memory Access and Control
CURRENT CPC
Cryptography
380/279
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181097 Caplan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David O. Caplan (Billerica, Massachusetts);  Walid A. Atia (Lexington, Massachusetts)
ABSTRACT A system includes an optical transmitter that outputs an optical signal having a substantially Gaussian waveform and an optical receiver that is optically coupled to the optical transmitter and has an impulse response essentially matching the waveform. The impulse response and waveform preferably match in the time domain. The transmitter and receiver may be average-power-limited, using, for example, an erbium-doped fiber amplifier. To achieve a high signal-to-noise ratio, the waveform may be designed to minimize jitter, sample duration, matching parasitics, and inter-symbol interference (ISI). Such a waveform may be a return-to-zero (RZ) Gaussian or Gaussian-like waveform and may be transmitted in a variety of modulation formats. Further, the system may be used in WDM or TDM systems. A method for characterizing the time domain impulse response of an optical element used in the optical receiver is provided, where the method is optionally optimized using deconvolution and/or cross-correlation techniques.
FILED Wednesday, March 13, 2002
APPL NO 10/097187
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181109 Kwakernaak
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Sernoff Corporation (Princeton, New Jersey)
INVENTOR(S) Martin H. Kwakernaak (New Brunswick, New Jersey)
ABSTRACT A monolithic device for photonically coupling a first optical waveguide to a second optical waveguide, including: an input being optically coupled to the first waveguide; a first portion being optically coupled to the input; a second portion being optically coupled to the first portion; and, an output being optically coupled to the second portion and the second waveguide; wherein, when an optical signal is provided on the first waveguide, a given part of the signal is provided to the second waveguide dependently upon an angle between the first and second portions. At least one of the waveguides may have an amorphous silicon material coating.
FILED Monday, February 28, 2005
APPL NO 11/068477
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/39
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181381 Akkaram et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Srikanth Akkaram (Troy, New York);  Dongming Gao (Clifton Park, New York);  Youdong Zhou (Niskayuna, New York)
ABSTRACT A method for performing new material development. The method comprises receiving a user simulation scenario from a user wherein the user simulation scenario is in a-cyclic graph format and includes a plurality of material development modules represented as vertices. The user simulation scenario also includes a starting module. Each vertex includes data information including at least one input file source and at least one output file destination. Relationships between the modules are represented as edges and each edge includes at least one of previous module and subsequent module. Each edge also includes data flow information between the previous module and the subsequent module. The method further comprises receiving a request to invoke the user simulation scenario and the request includes the input file source for the starting module. Traversing the vertices along the edges is performed in response to receiving the request and to the data flow information. The traversing includes executing the modules associated with each vertex beginning with the starting module in an order specified by the edges and the executing results in data being written to the output file destination for each vertex.
FILED Thursday, November 14, 2002
APPL NO 10/065740
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181743 Werme et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Paul V. Werme (Kinge George, Virginia);  Michael W. Masters (Fredericksburg, Virginia);  Larry A. Fontenot (King George, Virginia);  Lonnie R. Welch (Athens, Ohio)
ABSTRACT A resource manager for a distributed environment including hosts instantiating copies of a scalable application, generates signals which start up, shutdown or move a selected one of the copies responsive to first information regarding performance of all copies of the scalable application and second information regarding performance of the hosts.
FILED Thursday, May 24, 2001
APPL NO 09/864825
ART UNIT 2195 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Virtual machine task or process management or task management/control
718/104
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181768 Ghosh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Cigital (Dulles, Virginia)
INVENTOR(S) Anup K. Ghosh (Fairfax, Virginia);  Michael Schatz (Sterling, Virginia);  Christoph C. Michael (Reston, Virginia);  Aaron Schwartzbard (Reston, Virginia)
ABSTRACT An intrusion detection system (IDS) that uses application monitors for detecting application-based attacks against computer systems. The IDS implements application monitors in the form of a software program to learn and monitor the behavior of system programs in order to detect attacks against computer hosts. The application monitors implement machine learning algorithms to provide a mechanism for learning from previously observed behavior in order to recognize future attacks that it has not seen before. The application monitors include temporal locality algorithms to increased the accuracy of the IDS. The IDS of the present invention may comprise a string-matching program, a neural network, or a time series prediction algorithm for learning normal application behavior and for detecting anomalies.
FILED Monday, October 30, 2000
APPL NO 09/698159
ART UNIT 2134 — Interprocess Communication and Software Development
CURRENT CPC
Information security
726/23
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07178295 Dinwoodie
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) PowerLight Corporation (Berkeley, California)
INVENTOR(S) Thomas L. Dinwoodie (Piedmont, California)
ABSTRACT A barrier, such as a PV module, is secured to a base by a support to create a shingle assembly with a venting region defined between the barrier and base for temperature regulation. The first edge of one base may be interengageable with the second edge of an adjacent base to be capable of resisting first and second disengaging forces oriented perpendicular to the edges and along planes oriented parallel to and perpendicular to the base. A deflector may be used to help reduce wind uplift forces.
FILED Wednesday, February 20, 2002
APPL NO 10/078918
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/173.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07178391 Casper, legal representative et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Chris Casper, legal representative (Rigby, Idaho);  Don T. Clark (Idaho Falls, Idaho);  Blair K. Grover (Idaho Falls, Idaho);  Rodney O. Mathewson (Idaho Falls, Idaho);  Craig A. Seymour (Idaho Falls, Idaho)
ABSTRACT A drill string comprises a first drill string member having a male end; and a second drill string member having a female end configured to be joined to the male end of the first drill string member, the male end having a threaded portion including generally square threads, the male end having a non-threaded extension portion coaxial with the threaded portion, and the male end further having a bearing surface, the female end having a female threaded portion having corresponding female threads, the female end having a non-threaded extension portion coaxial with the female threaded portion, and the female end having a bearing surface. Installation methods, including methods of installing instrumented probes are also provided.
FILED Tuesday, August 09, 2005
APPL NO 11/200752
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/152.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07178608 Mayes et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Schlumberger Technology Corporation (Sugar Land, Texas)
INVENTOR(S) James C. Mayes (Sugar Land, Texas);  Mario A. Araya (Sugar Land, Texas);  Richard Edward Thorp (Richmond, Texas)
ABSTRACT A while drilling system and method for determining downhole parameters is provided. The system includes a retrievable while drilling tool positionable in a downhole drilling tool, a sensor chassis and at least one sensor. The while drilling tool is positionable in the downhole drilling tool and has a first communication coupler at an end thereof. The sensor chassis is supported in the drilling tool. The sensor chassis has a second communication coupler at an end thereof for operative connection with the first communication coupler. The sensor is positioned in the chassis and is adapted to measure internal and/or external parameters of the drilling tool. The sensor is operatively connected to the while drilling tool via the communication coupler for communication therebetween. The sensor may be positioned in the while drilling tool and retrievable with the drilling tool. Preferably, the system is operable in high temperature and high pressure conditions.
FILED Friday, May 28, 2004
APPL NO 10/709802
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Boring or penetrating the earth
175/48
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07178627 West et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Phillip B. West (Idaho Falls, Idaho);  James R. Fincke (Los Alamos, New Mexico);  Teddy R. Reed (Idaho Falls, Idaho)
ABSTRACT The invention provides methods and apparatus for detecting seismic waves propagating through a subterranean formation surrounding a borehole. In a first embodiment, a sensor module uses the rotation of bogey wheels to extend and retract a sensor package for selective contact and magnetic coupling to casing lining the borehole. In a second embodiment, a sensor module is magnetically coupled to the casing wall during its travel and dragged therealong while maintaining contact therewith. In a third embodiment, a sensor module is interfaced with the borehole environment to detect seismic waves using coupling through liquid in the borehole. Two or more of the above embodiments may be combined within a single sensor array to provide a resulting seismic survey combining the optimum of the outputs of each embodiment into a single data set.
FILED Thursday, March 16, 2006
APPL NO 11/378565
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Acoustics
181/122
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07178750 Thiry
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Califfornia (Oakland, California)
INVENTOR(S) Michael J. Thiry (Oakdale, California)
ABSTRACT An apparatus for reducing clogs in a pneumatic material feed line, such as employed in abrasive waterjet machining systems, by providing an evenflow feed of material therethrough. The apparatus preferably includes a hollow housing defining a housing volume and having an inlet capable of connecting to an upstream portion of the pneumatic material feed line, an outlet capable of connecting to a downstream portion of the pneumatic material feed line, and an air vent located between the inlet and outlet for venting excess air pressure out from the housing volume. A diverter, i.e. an impingement object, is located at the inlet and in a path of incoming material from the upstream portion of the pneumatic material feed line, to break up clumps of ambient moisture-ridden material impinging on the diverter. And one or more filter screens is also preferably located in the housing volume to further break up clumps and provide filtering.
FILED Thursday, April 01, 2004
APPL NO 10/817489
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Solid material comminution or disintegration
241/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179323 Stein et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Air Products and Chemicals, Inc. (Allentown, Pennsylvania)
INVENTOR(S) VanEric Edward Stein (Allentown, Pennsylvania);  Michael Francis Carolan (Allentown, Pennsylvania);  Christopher M. Chen (Allentown, Pennsylvania);  Phillip Andrew Armstrong (Orefield, Pennsylvania);  Harold W. Wahle (North Canton, Ohio);  Theodore R. Ohrn (Alliance, Ohio);  Kurt E. Kneidel (Alliance, Ohio);  Keith Gerard Rackers (Louisville, Ohio);  James Erik Blake (Uniontown, Ohio);  Shankar Nataraj (Allentown, Pennsylvania);  Rene Hendrik Elias van Doorn (Obersulm-Willsbach, Germany);  Merrill Anderson Wilson (West Jordan, Utah)
ABSTRACT An ion transport membrane system comprising (a) a pressure vessel having an interior, an exterior, an inlet, and an outlet; (b) a plurality of planar ion transport membrane modules disposed in the interior of the pressure vessel and arranged in series, each membrane module comprising mixed metal oxide ceramic material and having an interior region and an exterior region, wherein any inlet and any outlet of the pressure vessel are in flow communication with exterior regions of the membrane modules; and (c) one or more gas manifolds in flow communication with interior regions of the membrane modules and with the exterior of the pressure vessel. The ion transport membrane system may be utilized in a gas separation device to recover oxygen from an oxygen-containing gas or as an oxidation reactor to oxidize compounds in a feed gas stream by oxygen permeated through the mixed metal oxide ceramic material of the membrane modules.
FILED Wednesday, August 06, 2003
APPL NO 10/635695
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Gas separation: Processes
095/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179405 Ebbers et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Christopher A. Ebbers (Livermore, California);  Kathleen I. Schaffers (Pleasanton, California)
ABSTRACT A material for harmonic generation has been made by substitutional changes to the crystal LaCa4 (BO3)3 also known as LaCOB in the form Re1xRe2yRe3zCa4(BO3)3O where Re1 and Re2, (rare earth ion 1 and rare earth ion 2) are selected from the group consisting of Sc, Yttrium, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu; Re3 is Lanthanum; and x+y+z=1.
FILED Tuesday, October 01, 2002
APPL NO 10/261902
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Compositions
252/584
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179421 Ho
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Hampshire)
INVENTOR(S) Clifford K. Ho (Albuquerque, New Mexico)
ABSTRACT A multi-pin chemiresistor for use in microchemical sensors. A pair of free-standing, bare wires is supported by an electrically insulating support, and are oriented parallel to each other and spaced closely together. A free-standing film of a chemically sensitive polymer that swells when exposed to vapors of a volatile chemical is formed in-between the pair of closely-spaced wires by capillary action. Similar in construction to a thermocouple, this “chemicouple” is relatively inexpensive and easy to fabricate by dipping the pair of bare wires into a bath of well-mixed chemiresistor ink. Also, a chemiresistor “stick” is formed by dipping an electrically insulating rod with two or more linear or spiral-wrapped electrical traces into the bath of well-mixed chemiresistor ink, which deposits a uniform coating of the chemically sensitive polymer on the rod and the electrical traces. These “sticks” can be easily removed and replaced from a multi-chemiresistor plug.
FILED Thursday, January 23, 2003
APPL NO 10/349689
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/82.20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179591 Foote
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Robert S. Foote (Oak Ridge, Tennessee)
INVENTOR(S) Robert S. Foote (Oak Ridge, Tennessee)
ABSTRACT A method and apparatus are provided for performing light-directed reactions in spatially addressable channels within a plurality of channels. One aspect of the invention employs photoactivatable reagents in solutions disposed into spatially addressable flow streams to control the parallel synthesis of molecules immobilized within the channels. The reagents may be photoactivated within a subset of channels at the site of immobilized substrate molecules or at a light-addressable site upstream from the substrate molecules. The method and apparatus of the invention find particularly utility in the synthesis of biopolymer arrays, e.g., oligonucleotides, peptides and carbohydrates, and in the combinatorial synthesis of small molecule arrays for drug discovery.
FILED Wednesday, May 16, 2001
APPL NO 09/859028
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179598 Nolan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) John P. Nolan (Santa Fe, New Mexico);  Feng Zhou (Los Alamos, New Mexico)
ABSTRACT The present invention provides methods and kits for detecting chromosome translocations. The present invention further provides methods for diagnosing cancer.
FILED Wednesday, November 20, 2002
APPL NO 10/301300
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179602 Robinson
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Donna L. Robinson (Los Alamos, New Mexico)
ABSTRACT The present invention is directed to a PCR-based method of cycle sequencing DNA and other polynucleotide sequences having high CG content and regions of high GC content, and includes for example DNA strands with a high Cytosine and/or Guanosine content and repeated motifs such as CCT repeats.
FILED Thursday, September 04, 2003
APPL NO 10/656358
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179677 Ramanathan et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Midwest Research Institute (Kansas City, Missouri)
INVENTOR(S) Kannan Ramanathan (Golden, Colorado);  Falah S. Hasoon (Golden, Colorado);  Sarah E. Asher (Wheat Ridge, Colorado);  James Dolan (Arvada, Colorado);  James C. Keane (Lakewood, Colorado)
ABSTRACT A process for making a thin film ZnO/Cu(InGa)Se2 solar cell without depositing a buffer layer and by Zn doping from a vapor phase, comprising: depositing Cu(InGa)Se2 layer on a metal back contact deposited on a glass substrate; heating the Cu(InGa)Se2 layer on the metal back contact on the glass substrate to a temperature range between about 100° C. to about 250° C.; subjecting the heated layer of Cu(InGa)Se2 to an evaporant species from a Zn compound; and sputter depositing ZnO on the Zn compound evaporant species treated layer of Cu(InGa)Se2.
FILED Wednesday, September 03, 2003
APPL NO 10/534217
ART UNIT 1753 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Semiconductor device manufacturing: Process
438/95
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179679 Chiarelli et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Los Alamos, New Mexico)
INVENTOR(S) Peter A. Chiarelli (Scottsdale, Arizona);  Jeanne M. Robinson (Los Alamos, New Mexico);  Joanna L. Casson (Los Alamos, New Mexico);  Malkiat S. Johal (Bradenton, Florida);  Hsing-Lin Wang (Los Alamos, New Mexico)
ABSTRACT An process of forming multilayer thin film heterostructures is disclosed and includes applying a solution including a first water-soluble polymer from the group of polyanionic species, polycationic species and uncharged polymer species onto a substrate to form a first coating layer on the substrate, drying the first coating layer on the substrate, applying a solution including a second water-soluble polymer from the group of polyanionic species, polycationic species and uncharged polymer species onto the substrate having the first coating layer to form a second coating layer on the first coating layer wherein the second water-soluble polymer is of a different material than the first water-soluble polymer, and drying the second coating layer on the first coating layer so as to form a bilayer structure on the substrate. Optionally, one or more additional applying and drying sequences can be repeated with a water-soluble polymer from the group of polyanionic species, polycationic species and uncharged polymer species, so that a predetermined plurality of layers are built up upon the substrate.
FILED Friday, July 11, 2003
APPL NO 10/618517
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180055 Kallenbach et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Gene A. Kallenbach (Bosque Farms, New Mexico);  Frank T. Noda (Albuquerque, New Mexico);  Dean J. Mitchell (Tijeras, New Mexico);  Joshua L. Etzkin (Albuquerque, New Mexico)
ABSTRACT An apparatus and method are disclosed for a compact and temperature-insensitive nuclear sensor that can be calibrated with a non-hazardous radioactive sample. The nuclear sensor includes a gamma ray sensor that generates tail pulses from radioactive samples. An analog conditioning circuit conditions the tail-pulse signals from the gamma ray sensor, and a tail-pulse simulator circuit generates a plurality of simulated tail-pulse signals. A computer system processes the tail pulses from the gamma ray sensor and the simulated tail pulses from the tail-pulse simulator circuit. The nuclear sensor is calibrated under the control of the computer. The offset is adjusted using the simulated tail pulses. Since the offset is set to zero or near zero, the sensor gain can be adjusted with a non-hazardous radioactive source such as, for example, naturally occurring radiation and potassium chloride.
FILED Tuesday, August 09, 2005
APPL NO 11/199893
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/252.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180065 Craig et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Richard A. Craig (Richland, Washington);  Jeffrey W. Griffin (Kennewick, Washington)
ABSTRACT A low-cost infra-red detector is disclosed including a method of making and using the same. The detector employs a substrate, a filtering layer, a converting layer, and a diverter to be responsive to wavelengths up to about 1600 nm. The detector is useful for a variety of applications including spectroscopy, imaging, and defect detection.
FILED Thursday, September 30, 2004
APPL NO 10/957091
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/338.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180082 Hassanein et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) Ahmed Hassanein (Naperville, Illinois);  Isak Konkashbaev (Bolingbrook, Illinois);  Bryan Rice (Hillsboro, Oregon)
ABSTRACT A device and method for generating extremely short-wave ultraviolet electromagnetic wave, utilizing a theta pinch plasma generator to produce electromagnetic radiation in the range of 10 to 20 nm. The device comprises an axially aligned open-ended pinch chamber defining a plasma zone adapted to contain a plasma generating gas within the plasma zone; a means for generating a magnetic field radially outward of the open-ended pinch chamber to produce a discharge plasma from the plasma generating gas, thereby producing a electromagnetic wave in the extreme ultraviolet range; a collecting means in optical communication with the pinch chamber to collect the electromagnetic radiation; and focusing means in optical communication with the collecting means to concentrate the electromagnetic radiation.
FILED Tuesday, February 22, 2005
APPL NO 11/066655
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/504.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180204 Grant et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) James Jonathan Grant (Niskayuna, New York);  Bharat Sampathkumaran Bagepalli (Niskayuna, New York);  Patrick Lee Jansen (Scotia, New York);  Paul Stephen DiMascio (Greer, South Carolina);  Aniruddha Dattatraya Gadre (Rexford, New York);  Ronghai Qu (Clifton Park, New York)
ABSTRACT Methods and apparatus for assembling a wind turbine generator are provided. The wind turbine generator includes a core and a plurality of stator windings circumferentially spaced about a generator longitudinal axis, a rotor rotatable about the generator longitudinal axis wherein the rotor includes a plurality of magnetic elements coupled to a radially outer periphery of the rotor such that an airgap is defined between the stator windings and the magnetic elements and the plurality of magnetic elements including a radially inner periphery having a first diameter. The wind turbine generator also includes a bearing including a first member in rotatable engagement with a radially inner second member, the first member including a radially outer periphery, a diameter of the radially outer periphery of the first member being substantially equal to the first diameter, the rotor coupled to the stator through the bearing such that a substantially uniform airgap is maintained.
FILED Friday, January 07, 2005
APPL NO 11/031259
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Prime-mover dynamo plants
290/55
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180242 Rostoker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Norman Rostoker (Irvine, California);  Michl Binderbauer (Irvine, California);  Artan Qerushi (Irvine, California);  Hooshang Tahsiri (Irvine, California)
ABSTRACT A system and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions they are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels.
FILED Thursday, May 19, 2005
APPL NO 11/134776
ART UNIT 2821 — Electrical Circuits and Systems
CURRENT CPC
Electric lamp and discharge devices: Systems
315/111.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180402 Carrender et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute K1-53 (Richland, Washington)
INVENTOR(S) Curtis Lee Carrender (Morgan Hill, California);  Ronald W. Gilbert (Gilroy, California)
ABSTRACT A radio frequency (RF) communication system employs phase-modulated backscatter signals for RF communication from an RF tag to an interrogator. The interrogator transmits a continuous wave interrogation signal to the RF tag, which based on an information code stored in a memory, phase-modulates the interrogation signal to produce a backscatter response signal that is transmitted back to the interrogator. A phase modulator structure in the RF tag may include a switch coupled between an antenna and a quarter-wavelength stub; and a driver coupled between the memory and a control terminal of the switch. The driver is structured to produce a modulating signal corresponding to the information code, the modulating signal alternately opening and closing the switch to respectively decrease and increase the transmission path taken by the interrogation signal and thereby modulate the phase of the response signal. Alternatively, the phase modulator may include a diode coupled between the antenna and driver. The modulating signal from the driver modulates the capacitance of the diode, which modulates the phase of the response signal reflected by the diode and antenna.
FILED Friday, August 27, 2004
APPL NO 10/928712
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/10.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180404 Kunerth et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Dennis C. Kunerth (Idaho Falls, Idaho);  John M. Svoboda (Idaho Falls, Idaho);  James T. Johnson (Idaho Falls, Idaho);  L. Dean Harding (Chubbuck, Idaho);  Kerry M. Klingler (Idaho Falls, Idaho)
ABSTRACT A wireless sensor system includes a passive sensor apparatus configured to be embedded within a concrete structure to monitor infiltration of contaminants into the structure. The sensor apparatus includes charging circuitry and a plurality of sensors respectively configured to measure environmental parameters of the structure which include information related to the infiltration of contaminants into the structure. A reader apparatus is communicatively coupled to the sensor apparatus, the reader apparatus being configured to provide power to the charging circuitry during measurements of the environmental parameters by the sensors. The reader apparatus is configured to independently interrogate individual ones of the sensors to obtain information measured by the individual sensors. The reader apparatus is configured to generate an induction field to energize the sensor apparatus. Information measured by the sensor apparatus is transmitted to the reader apparatus via a response signal that is superimposed on a return induction field generated by the sensor apparatus. Methods of monitoring structural integrity of the structure are also provided.
FILED Wednesday, March 17, 2004
APPL NO 10/803517
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/10.410
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180918 Dane et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Metal Improvement Company, LLC (Paramus, New Jersey)
INVENTOR(S) C. Brent Dane (Livermore, California);  Lloyd Hackel (Livermore, California);  Fritz B. Harris (Rocklin, California)
ABSTRACT A method of operating a laser to obtain an output pulse having a single wavelength, comprises inducing an intracavity loss into a laser resonator having an amount that prevents oscillation during a time that energy from the pump source is being stored in the gain medium. Gain is built up in the gain medium with energy from the pump source until formation of a single-frequency relaxation oscillation pulse in the resonator. Upon detection of the onset of the relaxation oscillation pulse, the intracavity loss is reduced, such as by Q-switching, so that the built-up gain stored in the gain medium is output from the resonator in the form of an output pulse at a single frequency. An electronically controllable output coupler is controlled to affect output pulse characteristics. The laser acts a master oscillator in a master oscillator power amplifier configuration. The laser is used for laser peening.
FILED Thursday, October 30, 2003
APPL NO 10/696989
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180931 Melgaard et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David K. Melgaard (Albuquerque, New Mexico);  Joseph J. Beaman (Austin, Texas);  Gregory J. Shelmidine (Tijeras, New Mexico)
ABSTRACT An apparatus and method for controlling an electroslag remelting furnace comprising adjusting electrode drive speed by an amount proportional to a difference between a metric of electrode immersion and a set point, monitoring impedance or voltage, and calculating the metric of electrode immersion depth based upon a predetermined characterization of electrode immersion depth as a function of impedance or voltage.
FILED Tuesday, May 25, 2004
APPL NO 10/853477
ART UNIT 2832 — Semiconductors/Memory
CURRENT CPC
Industrial electric heating furnaces
373/49
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181110 Klingsporn
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Paul Edward Klingsporn (Lee's Summit, Missouri)
ABSTRACT An apparatus and method for combining light signals carried on a plurality of input fibers onto a single receiving fiber with a high degree of efficiency. The apparatus broadly comprises the receiving fiber and a plurality of input fiber-lens assemblies, with each fiber lens assembly including an input fiber; a collimating lens interposed between the input fiber and the receiving fiber and adapted to collimate the light signal; and a focusing lens interposed between the collimating lens and the receiving fiber and adapted to focus the collimated light signal onto the face of the receiving fiber. The components of each fiber-lens assembly are oriented along an optic axis that is inclined relative to the receiving fiber, with the inclination angle depending at least in part on the input fiber's numerical aperture and the focal lengths and diameters of the collimating and focusing lenses.
FILED Friday, December 30, 2005
APPL NO 11/323949
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/45
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181122 Levene et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Michael J. Levene (Ithaca, New York);  Jonas Korlach (Ithaca, New York);  Stephen W. Turner (Ithaca, New York);  Harold G. Craighead (Ithaca, New York);  Watt W. Webb (Ithaca, New York)
ABSTRACT The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.
FILED Tuesday, December 20, 2005
APPL NO 11/313971
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/132
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181377 Borden et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Michael J. Borden (Albuquerque, New Mexico);  Jason F. Shepherd (Albuquerque, New Mexico)
ABSTRACT A method and machine-readable medium provide a technique to modify a hexahedral finite element volume mesh using dual generation and sheet extraction. After generating a dual of a volume stack (mesh), a predetermined algorithm may be followed to modify the volume mesh of hexahedral elements. The predetermined algorithm may include the steps of determining a sheet of hexahedral mesh elements, generating nodes for merging, and merging the nodes to delete the sheet of hexahedral mesh elements and modify the volume mesh.
FILED Monday, June 23, 2003
APPL NO 10/601370
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/2
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07179448 Dattwyler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
U.S. State Government
State of New York
APPLICANT(S)
ASSIGNEE(S) Research Foundation of the State of New York (Stony Brook, New York);  Brookhaven Sciences Associates, LLC (Upton, New York)
INVENTOR(S) Raymond J. Dattwyler (Setauket, New York);  Maria J. C. Gomes-Solecki (New York, New York);  Benjamin J. Luft (East Setauket, New York);  John J. Dunn (Bellport, New York)
ABSTRACT Novel chimeric nucleic acids, encoding chimeric Borrelia proteins comprising OspC or an antigenic fragment thereof and OspA or an antigenic fragment thereof, are disclosed. Chimeric proteins encoded by the nucleic acid sequences are also disclosed. The chimeric proteins are useful as vaccine immunogens against Lyme borreliosis, as well as for immunodiagnostic reagents.
FILED Wednesday, August 03, 2005
APPL NO 11/196475
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179462 Srivastava et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Connecticut Health Center (Farmington, Connecticut)
INVENTOR(S) Pramod K. Srivastava (Avon, Connecticut);  Robert J. Binder (Farmington, Connecticut)
ABSTRACT The present invention relates to the use of alpha (2) macroglobulin (“α2M”) receptor as a heat shock protein receptor, cells that express the α2M receptor bound to an HSP, and antibodies and other molecules that bind the α2M receptor-HSP complex. The invention also relates to screening assays to identify compounds that interact with the α2M receptor, and modulate the interaction of the α2M receptor with its ligand, such as HSPs, and methods for using compositions comprising α2M-receptor sequences for the diagnosis and treatment of immune disorders, proliferative disorders, and infectious diseases.
FILED Thursday, December 28, 2000
APPL NO 09/750972
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179468 Lu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Min Lu (New York, New York);  Hong Ji (New York, New York)
ABSTRACT The present invention provides polypeptides comprising a stabilized trimer of the carboxyl-terminal core region of the ectodomain of an enveloped virus, such as HIV. A subject polypeptide comprises three monomers that form a trimeric coiled coil in a prefusogenic conformation of an enveloped virus such as HIV. The subject polypeptides are useful as vacciness against enveloped virus, such as HIV, which vaccines are also provided. The present invention also provides methods of vaccinating an individual to prevent or treat HIV infection or prevent or treat infection by another enveloped virus, using a subject vaccine. Antibodies or binding portions thereof raised against a C-terminus trimeric coiled coil motif of an HIV gp41 ectodomain, or carboxyl-terminal core region of the ectodomain of another enveloped virus, are also provided as are methods of making such antibodies. Methods for detecting HIV or other enveloped viruses in a sample, as well as methods of screening for drugs which can inhibit HIV infection or other enveloped virus infection, are also provided by the present invention.
FILED Friday, June 08, 2001
APPL NO 09/877606
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/188.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179588 Cabral
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Fernando Cabral (Houston, Texas)
ABSTRACT Tubulin mutations commonly associated with resistance to paclitaxel are defined, and PCR allele-specific primers capable of detecting the mutations in DNA from tumor cells are described as well as method for treating paclitaxel-resistant cells in tumors. A simple, rapid, and cost effective means for detecting paclitaxel-resistant cells in tumor biopsies from patients receiving paclitaxel therapy is disclosed.
FILED Thursday, May 18, 2000
APPL NO 09/574099
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179593 Roy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Arun K. Roy (San Antonio, Texas);  Yan Lavrovsky (Geneva, Switzerland);  Rakesh K. Tyagi (New Delhi, India);  Chung S. Song (San Antonio, Texas);  Bandana Chatterjee (San Antonio, Texas);  Shuo Chen (San Antonio, Texas)
ABSTRACT Highly specific hammerhead ribozymes are provided that human target estrogen receptor mRNA. These ribozymes, designated RZ1 through RZ7 provide predictable mRNA cleavage products. Methods for inhibiting estrogen-dependent tumor growth, such as that characteristic of breast cancer, are also provided employing these ribozymes. One or both of the ribozymes may be used together or separately with equal efficiency. The ribozymes possess a sequence region with a catalytic core that provides the attributed catalytic activity to these ribozymes.
FILED Friday, June 02, 2000
APPL NO 10/009420
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179613 Rizzo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Mark A. Rizzo (Nashville, Tennessee);  David W. Piston (Nashville, Tennessee)
ABSTRACT The present invention relates to providing novel therapeutics for treating diabetes other glycemic disorders. Such therapeutics involve the signaling pathways that contribute to regulation of glucose-stimulated insulin secretion. Of particular interest are modulators of a key component in the glucokinase pathway. Thus, the present provides methods of screening for modulators of glucokinase activity, expression, translocation, conformation, nitrosylation and interaction with other molecules as useful target for pharmacological manipulation in the treatment of diabetes and other glycemic disorders.
FILED Monday, May 03, 2004
APPL NO 10/838167
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/15
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179614 Margolskee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Mount Sinai School of Medicine (New York, New York);  University of Washington (Seattle, Washington)
INVENTOR(S) Robert Margolskee (Upper Montclair, New Jersey);  Joseph Beavo (Seattle, Washington)
ABSTRACT The present invention relates to novel methods of signal transduction in cells. In particular, the invention relates to signal transduction via a class of enzymes known as phosphodiesterase enzymes or PDEs. The invention also relates to a class of signaling molecules known as G-coupled protein receptors (GCPRs) and G-proteins. The invention provides novel methods to screen for and identify G-proteins and other compounds which modulate signaling by these two classes of proteins. In particular, the relates to novel assays which identify compounds that modulate (e.g., enhance or inhibit) binding between a PDE polypeptide and an effector activation domain of a G-protein.
FILED Friday, September 14, 2001
APPL NO 10/380393
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179615 Anstey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Menzies School of Health Research (Tiwi, Australia);  Duke University (Durham, North Carolina)
INVENTOR(S) Nicholas Mark Anstey (Jingili, Australia);  Joseph Brice Weinberg (Durham, North Carolina);  Donald L. Granger (Holladay, Utah)
ABSTRACT The present invention relates generally to a method for the prophylaxis and treatment of parasitic infections in animals and birds. More particularly, the present invention contemplates a method for the prophylaxis and treatment of Plasmodium infection in mammals and the prophylaxis and treatment of disease conditions caused or exacerbated by Plasmodium. Even more particularly, the present invention is directed to a method for the prophylaxis and treatment of malaria including ameliorating the clinical effects of malaria and agents useful for same.
FILED Wednesday, July 29, 1998
APPL NO 09/124485
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/32
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179618 Sano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of California (Oakland, California)
INVENTOR(S) Takeshi Sano (Albany, California);  Alexander N. Glazer (Orinda, California);  Charles R. Cantor (Berkeley, California)
ABSTRACT Streptavidin-metallothionein chimeric proteins with biological recognition specificity in which the streptavidin moiety provides high affinity biotin binding and the metallothionein moiety provides a high affinity metal binding. The binding affinity of the streptavidin-metallothionein chimeric protein both for biotin and heavy metal ions allows specific incorporation into, conjugation with, or labelling of any biological material containing biotin with various heavy metal ions.
FILED Friday, November 01, 2002
APPL NO 10/285876
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179621 Chader et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Gerald J. Chader (Bethesda, Maryland);  Ignacio R. Rodriguez (Rockville, Maryland);  Joyce Tombran-Tink (Derwood, Maryland);  Sofia Patricia Becerra (Bethesda, Maryland);  Fintan R. Steele (Washington, District of Columbia);  Lincoln V. Johnson (Pasadena, California)
ABSTRACT Nucleic acids encoding the neurotrophic protein known as pigment epithelium derived factor (PEDF), a truncated version of PEDF referred to as rPEDF, and equivalent proteins, vectors comprising such nucleic acids, host cells into which such vectors have been introduced, recombinant methods for producing PEDF, rPEDF, and equivalent proteins, the rPEDF protein and equivalent proteins of rPEDF and PEDF-BP, -BX and BA, and the PEDF protein produced by recombinant methods. Effects and uses of these variants on 1) neuronal differentiation (neurotrophic effect) 2) neuron survival (neuronotrophic effect) and 3) glial inhibition (gliastatic effect) are described.
FILED Tuesday, August 01, 2000
APPL NO 09/630629
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179627 Simmons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Brigham Young University (Provo, Utah)
INVENTOR(S) Daniel Simmons (Provo, Utah);  N. Vishvanath Chandrasekharan (Provo, Utah)
ABSTRACT The invention relates to the isolation of novel cyclooxygenase type 1 (COX-1) variant enzymes. More specifically, the invention relates to the identification of cyclooxygenase transcripts harboring inton 1, or fragment thereof, of cyclooxygenase 1. The invention further relates to the diagnosis of aberrant cyclooxygenase type 1 variant gene or gene product; the identification, production, and use of compounds which modulate cyclooxygenase type 1 variant gene expression or the activity of the cyclooxygenase type 1 variant gene product including but not limited to nucleic acid encoding cyclooxygenase type 1 variants and homologues, analogues, and deletions thereof, as well as antisense, ribozyme, triple helix, antibody, and polypeptide molecules as well as small inorganic molecules; and pharmaceutical formulations and routes of administration for such compounds.
FILED Saturday, September 28, 2002
APPL NO 10/260937
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/189
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179650 Yeh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, the University of Texas System (Austin, Texas)
INVENTOR(S) Edward T. H. Yeh (Houston, Texas)
ABSTRACT Disclosed are compositions comprising a novel cell-death protecting protein, sentrin-1, and the gene which encodes it. Also disclosed are methods of making and using sentrin polypeptides and nucleic acid segments in various diagnostic and pharmaceutical applications. In a preferred embodiment, overexpression of sentrin-1 confers protection against both anti-Fas/APO-1 and TNF-induced apoptosis.
FILED Tuesday, January 18, 2000
APPL NO 09/484964
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
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US 07179784 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Shuguang Zhang (Lexington, Massachusetts);  Sylvain Vauthey (Morges, Switzerland)
ABSTRACT This work describes a new class of short polypeptides that can self-assemble to form regular nanotubes with an average diameters of about 50 nm. These peptides (7 to 8 amino acids) have a structure very similar to those observed in surfactant molecules with a defined hydrophilic head group constituting of charged amino acids and a lipophilic tail made out of hydrophobic amino acids such as alanine, valine or leucine. Cryo-TEM micrographs show numerous three-fold junctions connecting the self-assembling nanostructures and thus leading to the formation of a rather dense network of entangled nanotubes. Additionally, the observation of clear openings at the end of the supramolecular structures confirms the presence of tubular organization.
FILED Wednesday, July 10, 2002
APPL NO 10/192832
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 07179797 McNeel
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Douglas McNeel (Madison, Wisconsin)
ABSTRACT A DNA vaccine for the treatment of prostate cancer, comprising a plasmid vector comprising a nucleotide sequence encoding prostatic acid phosphatase (PAP) operably linked to a transcription regulatory element, wherein upon administration to a mammal a cytotoxic immune reaction against cells expressing PAP is induced. In preferred embodiment, the PAP encoded is a xenoantigen highly homologous to the autoantigen PAP of the mammal. Also disclosed are methods for inducing prostatitis, or inducing immune reaction to PAP, or treating prostate cancer in a mammal, using the DNA vaccine and pharmaceutical compositions comprising the vaccine. Preferably, xenoantigen vaccination is followed by boosting with autoantigen PAP from the same animal species as the mammal being treated.
FILED Thursday, September 25, 2003
APPL NO 10/669474
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07179815 Zhu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Neurocrine Biosciences, Inc. (San Diego, California)
INVENTOR(S) Yun-Fei Zhu (San Diego, California);  Chen Chen (San Diego, California);  Fabio C. Tucci (San Diego, California);  Zhiqiang Guo (San Diego, California);  Timothy D. Gross (San Diego, California);  Martin Rowbottom (La Jolla, California);  R. Scott Struthers (Encinitas, California)
ABSTRACT GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure:
wherein A, Q, R1, R2, R3a, R3b, R4, R5, R6 and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
FILED Friday, December 17, 2004
APPL NO 11/016551
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/269
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US 07179834 Fenical et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) William Fenical (Del Mar, California);  Paul Jensen (San Diego, California);  Tracy Mincer (San Diego, California);  Robert H. R. Feling (La Jolla, California)
ABSTRACT The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi.
FILED Friday, June 20, 2003
APPL NO 10/600854
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/421
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US 07179888 Tweten et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Rodney K. Tweten (Edmond, Oklahoma);  Jody Melton (Alva, Oklahoma)
ABSTRACT A vaccine utilizing purified mutant alpha toxins from Clostridium septicum for humans and animals against infections caused by C septicum. Persons potentially affected by C. septicum infections include colonic cancer patients, diabetics, leukemia patients, and neutropenics. The alpha toxin mutant of the vaccine lacks the toxicity of a native C. septicum alpha toxin. A serum comprising antibodies raised to the alpha toxin mutant is also available for treating humans or animals against C. septicum infections. The serum may be used in a method for conferring passive immunity against C. septicum. Antibodies to the alpha toxin mutant may be used in diagnostic tests or in treatments to clear alpha toxin from bodily fluids. The mutant alpha toxin may be produced by recombinant methods using cDNA encoding the toxin, the cDNA contained for example in a plasmid or host cell.
FILED Wednesday, July 10, 2002
APPL NO 10/194489
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
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US 07179894 Gorenstein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) David G. Gorenstein (Houston, Texas);  David J. King (Galveston, Texas);  Daniel A. Ventura (Galveston, Texas);  Allan R. Brasier (Galveston, Texas)
ABSTRACT A random combinatorial selection method is disclosed for the construction of oligonucleotide aptamers in which nuclease resistance is conferred by the inclusion of modified nucleotides. The modified nucleotides are incorporated during PCR amplification to form achiral modified oligonucleotides. Thio-substituted aptamers are provided that bind tightly to the nuclear factor for human IL6 (NF-IL6).
FILED Thursday, April 11, 2002
APPL NO 10/120815
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
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US 07179897 Housman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David E. Housman (Newton, Massachusetts);  Elizabeth A. Preisinger (Roslindale, Massachusetts);  Aleksey G. Kazantsev (Boston, Massachusetts)
ABSTRACT Methods of identifying compounds that disrupt aggregation of aggregation-disposed polypeptides, such as huntingtin or beta-amyloid protein, are disclosed. Furthermore, an artificial polypeptide that contains an extended polyglutamine region and DNA that encodes the polypeptide are also disclosed.
FILED Friday, July 12, 2002
APPL NO 10/194584
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.400
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US 07179899 Mezes et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Peter S. Mezes (Old Lyme, Connecticut);  Ruth A. Richard (Midland, Michigan);  Kimberly S. Johnson (Gales Ferry, Connecticut);  Jeffrey Schlom (Potomac, Maryland);  Syed V. S. Kashmiri (Gaithersburg, Maryland);  Liming Shu (Gaithersburg, Maryland);  Eduardo A. Padlan (Kensington, Maryland)
ABSTRACT Novel composite and humanized anti-TAG-72 monoclonal antibodies, antibody fragments, and derivatives thereof using human subgroup IV kappa light chain framework regions.
FILED Wednesday, September 25, 2002
APPL NO 10/255478
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.530
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US 07180068 Brecher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Radiation Monitoring Devices, Inc. (Watertown, Massachusetts)
INVENTOR(S) Charles Brecher (Lexington, Massachusetts);  Vivek Nagarkar (Newton, Massachusetts)
ABSTRACT Scintillation materials of this invention have an alkali halide host material, a (first) scintillation dopant of various types, and a variety of second dopants (co-dopants). In another embodiment, the scintillation materials of this invention have an alkali halide host material, a (first) scintillation dopant of various types, a variety of second dopants (co-dopants), and a variety of third dopants (co-dopants). Co-dopants of this invention are capable of providing a second auxiliary luminescent cation dopant, capable of introducing an anion size and electronegativity mismatch, capable of introducing a mismatch of anion charge, or introducing a mismatch of cation charge in the host material.
FILED Wednesday, June 09, 2004
APPL NO 10/864063
ART UNIT 2875 — Optics
CURRENT CPC
Radiant energy
250/361.R00
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US 07181122 Levene et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Michael J. Levene (Ithaca, New York);  Jonas Korlach (Ithaca, New York);  Stephen W. Turner (Ithaca, New York);  Harold G. Craighead (Ithaca, New York);  Watt W. Webb (Ithaca, New York)
ABSTRACT The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.
FILED Tuesday, December 20, 2005
APPL NO 11/313971
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/132
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US 07181266 Frangioni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Beth Isreal Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) John V. Frangioni (Wayland, Massachusetts);  Moungi G. Bawendi (Cambridge, Massachusetts);  Sungjee Kim (Pasadena, California);  Yong Taik Lim (Duckjin-Gu, South Korea)
ABSTRACT A lymphatic system can be imaged with emissive semiconductor nanocrystals, for example, in the near infrared.
FILED Friday, February 06, 2004
APPL NO 10/772425
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Surgery
6/476
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US 07181287 Greenberg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert Greenberg (Los Angeles, California)
ABSTRACT The invention is directed to an implantable device to enable delivery of drugs to the retina. The device minimizes stress to the retina by virtue of its softness and smooth shape that conform to the retina. Drugs are delivered by osmosis or by the device dissolving. It may be connected to an externally mounted pump and drug reservoir that control the amount of drug. It contains one or more holes that are positioned to deliver drugs to the desired location. Drugs may stimulate the retina to enable vision in blind patients. Drugs may be injected directly inside the eye by a trans-scleral pump and valve drug delivery device.
FILED Wednesday, July 24, 2002
APPL NO 10/202248
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/116
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National Science Foundation (NSF) 

US 07179231 Ezenwa
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisys Technology Foundation, Inc., (Madison, Wisconsin)
INVENTOR(S) Bertram N. Ezenwa (Mequon, Wisconsin)
ABSTRACT An apparatus for and method of conducting a nerve conduction study is provided. In response to predetermined stimulation from an excitation device, a signal is generated that travels through a human body. The apparatus includes a sensing electrode operatively engagable with the human body downstream of the excitation device for sensing the signal. The apparatus further includes a pressure mounting structure operatively connected to the sensing electrode for controlling the pressure at which the sensing electrode engages the body. The pressure mounting structure includes a pressure source and a pressure sensor. A controller receives a pressure signal from the pressure sensor and the signal from the sensor electrode. The controller includes software to normalize the amplitude of the signal based on the pressure at which the sensing electrode engages the body.
FILED Monday, August 25, 2003
APPL NO 10/647495
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/554
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US 07179356 Aksay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Ilhan A. Aksay (Princeton, New Jersey);  Mathias Trau (Balmosal, Australia);  Srinivas Manne (Tucson, Arizona);  Itaru Honma (Chiba, Japan);  George Whitesides (Newton, Massachusetts)
ABSTRACT A process directed to preparing surfactant-polycrystalline inorganic nanostructured materials having designed microscopic patterns. The process includes forming a polycrystalline inorganic substrate having a flat surface and placing in contact with the flat surface of the substrate a surface having a predetermined microscopic pattern. An acidified aqueous reacting solution is then placed in contact with an edge of the surface having the predetermined microscopic pattern. The solution wicks into the microscopic pattern by capillary action. The reacting solution has an effective amount of a silica source and an effective amount of a surfactant to produce a mesoscopic silica film upon contact of the reacting solution with the flat surface of the polycrystalline inorganic substrate and absorption of the surfactant into the surface. Subsequently an electric field is applied tangentially directed to the surface within the microscopic pattern. The electric field is sufficient to cause electro-osmotic fluid motion and enhanced rates of fossilization by localized Joule heating.
FILED Friday, April 11, 2003
APPL NO 10/411641
ART UNIT 1753 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical and wave energy
24/450
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US 07179381 Sorenson, Jr.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) SRP Technologies, Inc. (Idaho Falls, Idaho)
INVENTOR(S) Kent S. Sorenson, Jr. (Idaho Falls, Idaho)
ABSTRACT A method for treating contamination in subsurface formations includes fracturing the soil to produce a network of fractures in the formation and simultaneously injecting a slurry containing an optional proppant and a solid-phase or nonaqueous-phase treatment agent into the network of fractures. The proppant is for keeping the fractures open, and the treatment agent accelerates conversion of the contaminants into immobile or less toxic forms. Chitin is an illustrative solid-phase treatment agent, which functions as an electron donor for anaerobic reductive dechlorination mediated by dechlorinating bacteria.
FILED Thursday, April 01, 2004
APPL NO 10/817163
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/610
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US 07179383 Porter et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Iowa State University Research Foundation (Ames, Iowa)
INVENTOR(S) Marc D Porter (Ames, Iowa);  Jing Ni (San Jose, California);  G Brent Dawson (San Jose, California);  Ruth Shinar (Ames, Iowa);  Robert J Lipert (Ames, Iowa);  Michael C Granger (Gilbert, Iowa);  Mark Tondra (Minneapolis, Minnesota)
ABSTRACT Method and apparatus for manipulating and monitoring analyte flowing in fluid streams. A giant magnetoresistive sensor has an array of sensing elements that produce electrical output signals which vary in dependence on changes in the magnetic field proximate the sensing elements. The analyte is included in a stream, such that the stream has a magnetic property which is dependent on the concentration and distribution on the analyte therein. The stream is flowed past the giant magnetoresistive sensor and in sufficiently close proximity to cause the magnetic properties of the stream to produce electrical output signals. The electrical output signals are monitored as an indicator of analyte concentration or distribution in the stream flowing past the GMR sensor. Changes in the magnetic field produced by the background stream are introduced by analyte molecules, whose presence in the flow past the GMR will effect the output reading.
FILED Thursday, March 04, 2004
APPL NO 10/793058
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/695
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US 07179508 Hanley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Luke Hanley (Chicago, Illinois);  Sanja Tepavcevic (Chicago, Illinois);  Yongsoo Choi (Chicago, Illinois)
ABSTRACT Conducting polymers having improved optical properties, and a method of manufacturing the conducting polymers, are disclosed. The conducting polymers are prepared by a process wherein organic ions and neutral oligomers are deposited simultaneously on a substrate surface to provide a conducting polymer film.
FILED Monday, May 17, 2004
APPL NO 10/847503
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/525
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US 07179614 Margolskee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Mount Sinai School of Medicine (New York, New York);  University of Washington (Seattle, Washington)
INVENTOR(S) Robert Margolskee (Upper Montclair, New Jersey);  Joseph Beavo (Seattle, Washington)
ABSTRACT The present invention relates to novel methods of signal transduction in cells. In particular, the invention relates to signal transduction via a class of enzymes known as phosphodiesterase enzymes or PDEs. The invention also relates to a class of signaling molecules known as G-coupled protein receptors (GCPRs) and G-proteins. The invention provides novel methods to screen for and identify G-proteins and other compounds which modulate signaling by these two classes of proteins. In particular, the relates to novel assays which identify compounds that modulate (e.g., enhance or inhibit) binding between a PDE polypeptide and an effector activation domain of a G-protein.
FILED Friday, September 14, 2001
APPL NO 10/380393
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/19
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US 07180066 Qiu
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Chang-Hua Qiu (Plainsboro, New Jersey)
ABSTRACT A quantum-well infrared photodetector (QWIP) is presented. The photodetector includes a substrate, a buffer layer, a first conductive layer, a multiple quantum well, an optional blocking layer, and a second conductive layer. Substrate is composed of a monocrystal which may be removed after fabrication. Remaining layers are composed of group III-V nitrides, including binary, ternary, and quaternary compositions. Alternate embodiments of the present invention include a doped binary alloy along first and second conductive layers, a binary alloy along buffer and blocking layers, and alternating alloys of binary, ternary and quaternary compositions within the multiple quantum well. The present invention responds to infrared light at normal and oblique incidences, from near infrared to very far infrared.
FILED Wednesday, November 24, 2004
APPL NO 10/996766
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/338.400
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US 07180135 Ioannou et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) George Mason Intellectual Properties, Inc. (Fairfax, Virginia)
INVENTOR(S) Dimitris E. Ioannou (Fairfax, Virginia);  Souvick Mitra (Burlington, Vermont);  Akram Salman (Sunnyvale, California)
ABSTRACT Disclosed is a Silicon-On-Insulator (SOI) Metal-Oxide Semiconductor Field-Effect Transistor (MOSFET) logic family composed of ratioed logic with intrinsically “on” symmetric fully depleted double-gate (DG) SOI MOSFET load(s) and asymmetric fully depleted double gate MOSFET driver(s).
FILED Wednesday, September 29, 2004
APPL NO 10/951695
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/347
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US 07180389 Wang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S) Shuo Wang (Blacksburg, Virginia);  Fred C. Lee (Blacksburg, Virginia);  Williem Gerhardus Odendaal (Blacksburg, Virginia)
ABSTRACT An electromagnetic interference (EMI) filter or frequency filters (e.g. bandpass or band reject filters) in which a capacitor has an inductance cancellation loop. Inductive coupling between capacitors can allow undesired high frequencies to propagate across a filter. This is particularly a concern when the capacitors are oriented in parallel. In the present invention, the inductance cancellation loop is disposed adjacent to one capacitor so that mutual inductance between the capacitors is reduced. The attenuation of the filter at high frequencies is thereby increased. The loop can increase voltage attenuation of an EMI filter by about 20 dB. In another aspect, inductors in the filter are oriented horizontally relative to a circuitboard. Horizontal orientation reduces leakage inductance coupling between the inductors and circuitboard traces, and between the inductor and capacitors, thereby preventing unwanted propagation of high frequencies. Both measures in combination can provide a voltage attenuation increase of 30 dB.
FILED Friday, December 17, 2004
APPL NO 11/013930
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/181
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US 07181122 Levene et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Michael J. Levene (Ithaca, New York);  Jonas Korlach (Ithaca, New York);  Stephen W. Turner (Ithaca, New York);  Harold G. Craighead (Ithaca, New York);  Watt W. Webb (Ithaca, New York)
ABSTRACT The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.
FILED Tuesday, December 20, 2005
APPL NO 11/313971
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/132
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181221 Mark et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) George Mason Intellectual Properties, Inc. (Fairfax, Virginia)
INVENTOR(S) Brian L. Mark (Fairfax, Virginia);  Alexe E. Leu (Arlington, Virginia)
ABSTRACT Disclosed is a system for evaluating the performance of cellular network handoff decisions. One embodiment of this system includes the steps of: creating a reference cellular network description; creating reduced geometric structures from the reference cellular network description; representing a general trajectory for a mobile unit in the reference cellular network description; approximating the general trajectory with a piecewise path having a multitude of handoff decision points; selecting a handoff mechanism; selecting handoff parameters; creating a discrete-time formulation characterizing handoff behaviors; and calculating at least one handoff performance metric. The handoff performance metrics may include assignment probabilities; handoff probabilities; a mean number of handoff value; a crossover point; and overall signaling load incurred by a handoff mechanism.
FILED Friday, September 26, 2003
APPL NO 10/670467
ART UNIT 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Telecommunications
455/436
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181266 Frangioni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Beth Isreal Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) John V. Frangioni (Wayland, Massachusetts);  Moungi G. Bawendi (Cambridge, Massachusetts);  Sungjee Kim (Pasadena, California);  Yong Taik Lim (Duckjin-Gu, South Korea)
ABSTRACT A lymphatic system can be imaged with emissive semiconductor nanocrystals, for example, in the near infrared.
FILED Friday, February 06, 2004
APPL NO 10/772425
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Surgery
6/476
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07179217 Goodwin et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Regenetech, Inc. (Sugar Land, Texas);  The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Thomas J. Goodwin (Kemah, Texas);  Clayton R. Parker (Safety Harbor, Florida)
ABSTRACT An apparatus is disclosed for enhancing tissue repair in mammals, with the apparatus comprising: a sleeve for encircling a portion of a mammalian body part, said sleeve comprising an electrically conductive coil capable of generating an electromagnetic field when an electrical current is applied thereto, means for supporting the sleeve on the mammalian body part; and means for supplying the electrically conductive coil with a square wave time varying electrical current sufficient to create a time varying electromagnetic force of from approximately 0.05 gauss to 0.05 gauss within the interior of the coil in order that when the sleeve is placed on a mammalian body part and the time varying electromagnetic force of from approximately 0.05 gauss to 0.05 gauss is generated on the mammalian body part for an extended period of time, tissue regeneration within the mammalian body part is increased to a rate in excess of the normal tissue regeneration rate that would occur without application of the time varying electromagnetic force.
FILED Wednesday, June 29, 2005
APPL NO 11/169614
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179404 Viswanathan
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Tito Viswanathan (Little Rock, Arkansas)
ABSTRACT The invention provides coatings useful for preventing corrosion of metals. The coatings comprise a film-forming resin and conductive polymers comprising linearly conjugated π-systems and residues of sulfonated lignin or a sulfonated polyflavonoid or derivatives of solfonated lignin or a sulfonated polyflavonoid. The invention also provides a latex formulation of the coatings, and articles of manufacture comprising a metal substrate and a coating in contact with the metal substrate.
FILED Friday, August 26, 2005
APPL NO 11/215205
ART UNIT 1751 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compositions
252/500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180943 Arlid et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Bertelrud Arlid (Hampton, Virginia);  Franz Russell (Lancaster, California)
ABSTRACT A stream of raw data is compressed prior to transmission in a communication channel by a system which includes modules for choosing a current segment of the raw data stream for processing and defining a set of operators for representing data segments by a mathematical operation and parameters thereof. The system performs a competitive evaluation of different tools comprising different combinations of one or more of the operators and the parameters thereof with respect to the current data segment in order to determine relative abilities among the different tools to reduce the number of bits required to represent the current data segment. The system then selects a tool and a set of parameters thereof found in the competitive evaluation to have a superior ability relative to others of the different tools to reduce a number of bits required to represent the current data segment.
FILED Tuesday, March 26, 2002
APPL NO 10/113637
ART UNIT 2621 — Selective Visual Display Systems
CURRENT CPC
Pulse or digital communications
375/240.60
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07178295 Dinwoodie
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) PowerLight Corporation (Berkeley, California)
INVENTOR(S) Thomas L. Dinwoodie (Piedmont, California)
ABSTRACT A barrier, such as a PV module, is secured to a base by a support to create a shingle assembly with a venting region defined between the barrier and base for temperature regulation. The first edge of one base may be interengageable with the second edge of an adjacent base to be capable of resisting first and second disengaging forces oriented perpendicular to the edges and along planes oriented parallel to and perpendicular to the base. A deflector may be used to help reduce wind uplift forces.
FILED Wednesday, February 20, 2002
APPL NO 10/078918
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/173.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179381 Sorenson, Jr.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) SRP Technologies, Inc. (Idaho Falls, Idaho)
INVENTOR(S) Kent S. Sorenson, Jr. (Idaho Falls, Idaho)
ABSTRACT A method for treating contamination in subsurface formations includes fracturing the soil to produce a network of fractures in the formation and simultaneously injecting a slurry containing an optional proppant and a solid-phase or nonaqueous-phase treatment agent into the network of fractures. The proppant is for keeping the fractures open, and the treatment agent accelerates conversion of the contaminants into immobile or less toxic forms. Chitin is an illustrative solid-phase treatment agent, which functions as an electron donor for anaerobic reductive dechlorination mediated by dechlorinating bacteria.
FILED Thursday, April 01, 2004
APPL NO 10/817163
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/610
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07179458 Chang et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Osel, Inc. (Santa Clara, California)
INVENTOR(S) Chia-Hwa Chang (Mountain View, California);  David A. Simpson (Redwood City, California);  Theresa Li-Yun Chang (Los Gatos, California);  Qiang Xu (Cupertino, California);  John A. Lewicki (Los Gatos, California)
ABSTRACT The present invention relates to Lactobacillus species recombinantly altered to express a biologically active protein. The invention also related to methods of providing the bacteria to the vagina.
FILED Thursday, March 06, 2003
APPL NO 10/383834
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07179905 McGall et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S)
ASSIGNEE(S) Affymetrix, Inc. (Santa Clara, California)
INVENTOR(S) Glenn McGall (Mountain View, California);  Anthony D. Barone (San Jose, California)
ABSTRACT Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.
FILED Monday, June 02, 2003
APPL NO 10/452519
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/25.320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181259 Tsuzuki et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Conductus, Inc. (Sunnyvale, California)
INVENTOR(S) Genichi Tsuzuki (Ventura, California);  Shen Ye (Cupertino, California)
ABSTRACT A resonator and filter including the resonator is disclosed. The resonator (100) includes an open conductive loop (100) with folded transmission line segments (124, 134) extending from the adjacent ends of the loop. Of each transmission line segment, the portion emanating from the respective end of the loop is positioned generally along-side the corresponding portion of the other transmission line segment. That is, the two transmission line segments are folded away from each other. The resonator can be generally elongated in shape, with the loop at one end of the long axis and the transmission line segments at the other. The transmission line segments occupy a footprint (W2) that is not substantially greater than the width of the loop (W1). The filter includes multiple resonators of the invention, each resonator being coupled to at least another or the resonators. The resonators can be positioned in a side-by-side fashion, with the long axes of the resonators parallel or anti-parallel to one another.
FILED Thursday, June 13, 2002
APPL NO 10/480743
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Superconductor technology: Apparatus, material, process
55/210
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 07179986 Harman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Theodore C. Harman (Lexington, Massachusetts);  Patrick J. Taylor (Woburn, Massachusetts);  Michael P. Walsh (Lunenburg, Massachusetts);  Brian E. LaForge (Tyngsboro, Massachusetts)
ABSTRACT A thermoelectric (TE) device includes a first leg of TE material (a pseudobinary or pseudoternary alloy) and a second leg comprising a metal wire. The second leg is in thermal and electrical communication with the first leg. The TE device has a ZT value of approximately 2.0 at a temperature of approximately 300K.
FILED Thursday, May 08, 2003
APPL NO 10/431747
ART UNIT 1753 — Organic Chemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07181097 Caplan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David O. Caplan (Billerica, Massachusetts);  Walid A. Atia (Lexington, Massachusetts)
ABSTRACT A system includes an optical transmitter that outputs an optical signal having a substantially Gaussian waveform and an optical receiver that is optically coupled to the optical transmitter and has an impulse response essentially matching the waveform. The impulse response and waveform preferably match in the time domain. The transmitter and receiver may be average-power-limited, using, for example, an erbium-doped fiber amplifier. To achieve a high signal-to-noise ratio, the waveform may be designed to minimize jitter, sample duration, matching parasitics, and inter-symbol interference (ISI). Such a waveform may be a return-to-zero (RZ) Gaussian or Gaussian-like waveform and may be transmitted in a variety of modulation formats. Further, the system may be used in WDM or TDM systems. A method for characterizing the time domain impulse response of an optical element used in the optical receiver is provided, where the method is optionally optimized using deconvolution and/or cross-correlation techniques.
FILED Wednesday, March 13, 2002
APPL NO 10/097187
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 07180920 Denney et al.
FUNDED BY
Department of Homeland Security (DHS)
Federal Emergency Management Agency (FEMA)
APPLICANT(S)
ASSIGNEE(S) Loma Linda University Medical Center (Loma Linda, California)
INVENTOR(S) Paul E. Denney (Columbus, Ohio);  Jay R. Eastman (Westerville, Ohio);  Paul M. Fallara (Columbus, Ohio);  Andrew P. Joseph (Johnstown, Ohio);  John S. Phillips (Powell, Ohio);  Ta-Chieh Huang (Dublin, Ohio);  Michael N. Patena (Pataskala, Ohio);  Tim Burnham (Reynoldsburg, Ohio);  Paul Coleman (Murfreesboro, Tennessee)
ABSTRACT An apparatus processes a surface of an inhabitable structure. The apparatus includes a laser base unit adapted to provide laser light to an interaction region, the laser light removing material from the structure. The laser base unit includes a laser generator and a laser head coupled to the laser generator. The laser head is adapted to remove the material from the interaction region, thereby providing reduced disruption to activities within the structure. The apparatus further includes an anchoring mechanism adapted to be releasably coupled to the structure and releasably coupled to the laser head. The apparatus further includes a controller electrically coupled to the laser base unit. The controller is adapted to transmit control signals to the laser base unit in response to user input.
FILED Thursday, March 18, 2004
APPL NO 10/803272
ART UNIT 2821 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/38.20
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07179381 Sorenson, Jr.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) SRP Technologies, Inc. (Idaho Falls, Idaho)
INVENTOR(S) Kent S. Sorenson, Jr. (Idaho Falls, Idaho)
ABSTRACT A method for treating contamination in subsurface formations includes fracturing the soil to produce a network of fractures in the formation and simultaneously injecting a slurry containing an optional proppant and a solid-phase or nonaqueous-phase treatment agent into the network of fractures. The proppant is for keeping the fractures open, and the treatment agent accelerates conversion of the contaminants into immobile or less toxic forms. Chitin is an illustrative solid-phase treatment agent, which functions as an electron donor for anaerobic reductive dechlorination mediated by dechlorinating bacteria.
FILED Thursday, April 01, 2004
APPL NO 10/817163
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Liquid purification or separation
210/610
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 07179448 Dattwyler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
U.S. State Government
State of New York
APPLICANT(S)
ASSIGNEE(S) Research Foundation of the State of New York (Stony Brook, New York);  Brookhaven Sciences Associates, LLC (Upton, New York)
INVENTOR(S) Raymond J. Dattwyler (Setauket, New York);  Maria J. C. Gomes-Solecki (New York, New York);  Benjamin J. Luft (East Setauket, New York);  John J. Dunn (Bellport, New York)
ABSTRACT Novel chimeric nucleic acids, encoding chimeric Borrelia proteins comprising OspC or an antigenic fragment thereof and OspA or an antigenic fragment thereof, are disclosed. Chimeric proteins encoded by the nucleic acid sequences are also disclosed. The chimeric proteins are useful as vaccine immunogens against Lyme borreliosis, as well as for immunodiagnostic reagents.
FILED Wednesday, August 03, 2005
APPL NO 11/196475
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07179901 Sanicola-Nadel et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Biogen Idec MA Inc. (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Michele Sanicola-Nadel (Winchester, Massachusetts);  Catherine Hession (Hingham, Massachusetts);  Richard Tizard, Jr. (Framingham, Massachusetts);  Joseph Bonventre (Wayland, Massachusetts)
ABSTRACT Disclosed are cis-acting regulatory elements from a KIM-1 gene. The elements can be used to direct the expression of operably linked sequences in renal tissue.
FILED Friday, June 15, 2001
APPL NO 10/311388
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07180067 Wolske
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Jeff S. Wolske (Tucson, Arizona)
ABSTRACT An infrared imaging system uses an uncooled elliptical surface section between reflective surfaces to allow a detector to perceive a cold interior of a vacuum chamber rather than a warmer surface of a structure or housing. In this way, background infrared radiation from within the system may be minimized.
FILED Tuesday, February 15, 2005
APPL NO 11/059159
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/353
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, February 20, 2007.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2007/fedinvent-patents-20070220.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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