FedInvent™ Patents

Patent Details for Tuesday, April 24, 2007 

This page was updated on Sunday, March 26, 2023 at 08:41 PM GMT

Department of Defense (DOD) 

US 07207252 Boyer, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Charles T. Boyer, Jr. (King George, Virginia);  Michael K. Oetjen (Alexandria, Virginia);  Din-chih Hwang (Fredericksburg, Virginia);  Robert V. Krueger (King George, Virginia);  Raymond D. Cooper (Bowling Green, Virginia)
ABSTRACT Determining cook-off time for a weapon is disclosed. A method determines a first barrel temperature next to a first energetic, such as a propellant charge, of ammunition within a gun barrel, and determines a second barrel temperature next to a second energetic, such as an explosive charge, of the ammunition. If the ammunition did not properly fire, the method determines a first cook-off time of the first energetic based on the first temperature next to the first energetic and the first energetic's type, and a second cook-off time of the second energetic based on the second temperature next to the second energetic and the second energetic's type. The first and second times may be determined by using one or more finite-difference heat transfer models. If either or both of the first and second times are less than a threshold, a warning-related action is performed to users of the weapon.
FILED Monday, May 08, 2006
APPL NO 11/434581
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207258 Scanlon
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Michael V. Scanlon (Laurel, Maryland)
ABSTRACT Silencers are provided for a weapon having a combustion chamber and a barrel. The weapon is configured to launch a projectile with combustion gases generated in the combustion chamber. An exemplary silencer includes a proximal end and a distal end, the proximal end being configured for mounting the silencer to the barrel, the distal end being configured to allow the projectile to pass therethrough, and at least one vortex chamber disposed between the proximal end and the distal end. The at least one vortex chamber includes a circular peripheral wall for inducing a vortex on a portion of the combustion gases expelled from the combustion chamber during launch of the projectile. The vortex impedes flow of the combustion gases from the barrel such that acoustic energy associated with the launch of the projectile is dissipated.
FILED Friday, December 10, 2004
APPL NO 11/009855
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/198
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207276 Dindl
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Frank Dindl (Newton, New Jersey)
ABSTRACT A non-lethal ammunition utilizes dense powder ballast and a two-stage firing sequence for launching non-lethal projectiles of a caliber range from approximately 5.56 mm through approximately 40 mm. The non-lethal ammunition comprises a non-lethal cartridge. The non-lethal cartridge comprises a dense powder ballast and one or more non-lethal projectiles. The dense powder ballast is more massive than the non-lethal projectile providing sufficient payload mass to operate the weapon mechanism while launching the non-lethal projectile at velocities compatible with non-lethal applications. A two-stage ignition system fires the non-lethal ammunition and subsequently fires the more massive dense powder ballast. The firing events are separated by a time delay of less than a second. The non-lethal ammunition provides non-lethal projectile capability for semi-automatic and automatic weapons. Rifling imparts sufficient spin to the ballast material to efficiently disperse the dense powder upon muzzle exit and decelerate the ballast cup and contents to an “eye safe” non-lethal velocity at the target. The cartridge case may be smooth bore for use in rifled barrels, or may be rifled for use in smooth bore barrels.
FILED Wednesday, August 25, 2004
APPL NO 10/711121
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/502
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207352 Sadil
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Andreas Sadil (Newington, Connecticut)
ABSTRACT A bypass air metering valve is provided with a stationary case flange having a plurality of slots, a bushing positioned within each of the slots, and a metering ring positioned so as to ride on a surface of each respective bushing. Each bushing creates a gap between the stationary case flange and the metering ring. Each bushing has an internal opening which is sized to create an open area flow for cooling or operating the nozzle and its attaching flap hardware. The metering ring covers and uncovers the internal opening of each bushing as required by the engine operating schedule.
FILED Monday, May 02, 2005
APPL NO 11/120700
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/625.310
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207725 Antonelli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lynn T. Antonelli (Cranston, Rhode Island);  Patrick J. Monahan (Gales Ferry, Connecticut)
ABSTRACT Optical fiber coupler for coupling fiber optic elements includes a first fiber optic element extending in a first direction to position a free end thereof in a selected zone, and a second fiber optic element extending into the selected zone from an opposite direction to position a free end of the second fiber optic element in the zone confronting the first fiber optic element free end. A cured optical grade epoxy resin body defines the zone and envelopes the free ends of the fiber optic elements, to effect physical and optical connection between the first and second fiber optic elements. Once cured, the housing material is removed leaving the completed coupler device. The free ends of the fiber optic elements are in close proximity, or in the case of coupling from one strand to a plurality of strands, in enough of a spaced relation, to permit required light diffusion.
FILED Tuesday, August 19, 2003
APPL NO 10/644549
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208094 Islam et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S) M. Saif Islam (Mountain View, California);  Theodore I. Kamins (Palo Alto, California);  Shashank Sharma (Mountain View, California)
ABSTRACT A semiconductor nanowire is grown laterally. A method of growing the nanowire forms a vertical surface on a substrate, and activates the vertical surface with a nanoparticle catalyst. A method of laterally bridging the nanowire grows the nanowire from the activated vertical surface to connect to an opposite vertical surface on the substrate. A method of connecting electrodes of a semiconductor device grows the nanowire from an activated device electrode to an opposing device electrode. A method of bridging semiconductor nanowires grows nanowires between an electrode pair in opposing lateral directions. A method of self-assembling the nanowire bridges the nanowire between an activated electrode pair. A method of controlling nanowire growth forms a surface irregularity in the vertical surface. An electronic device includes a laterally grown nano-scale interconnection.
FILED Wednesday, December 17, 2003
APPL NO 10/738176
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Etching a substrate: Processes
216/2
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US 07208120 Bitensky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Mark W. Bitensky (Waban, Massachusetts);  Tatsuro Yoshida (Newton, Massachusetts);  Michael G. Frank (East Lansing, Michigan);  Christopher V Gabel (Sumerville, Massachusetts);  Jure Derganc (Ljubljana, Slovenia)
ABSTRACT A cellular diagnostic array has been developed that provides accurate and reproducible measurements of the physical parameters of individual cells en masse, including cell membrane surface area, cell volume, and excess membrane. Three differing patterns are employed. In the first design, a gradient array having rectangular shaped channels is used to capture cells and readily show the ratio of volume to surface area for the captured cell. The second silicone rubber array provided by the present invention employs an array of wedge shaped pipettes, each of which captures an individual cell. The position of the cell within a wedge is enough to rapidly determine the cell's actual surface area and volume. A third type of cellular diagnostic array according to the present invention employs an array of channels designed to deform a cell to study how well the cell responds to repeated deformations.
FILED Thursday, September 27, 2001
APPL NO 09/965644
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/68.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208122 Swager et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Jye-Shane Yang (Ping-Chen, Taiwan);  Vance Williams (Somerville, Massachusetts);  Yi-Jun Miao (Chester, Virginia);  Claus G. Lugmair (San Jose, California);  Igor A. Levitsky (Fall River, Massachusetts);  Jinsang Kim (Cambridge, Massachusetts);  Robert Deans (Cambridge, Massachusetts)
ABSTRACT The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer.
FILED Wednesday, December 18, 2002
APPL NO 10/324064
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/82.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208133 Cho et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Kyung-Sang Cho (Kwacheon, South Korea);  Wolfgang Gaschler (Ludwigshafen, Germany);  Christopher B. Murray (Ossining, New York);  Dmitri Talapin (Ossining, New York)
ABSTRACT A high temperature non-aqueous synthetic procedure for the preparation of substantially monodisperse IV-VI semiconductor nanoparticles is provided. The procedure includes introducing a first precursor selected from the group consisting of a molecular precursor of a Group IV element and a molecular precursor of a Group VI element into a reaction vessel that comprises at least an organic solvent to form a mixture. Next, the mixture is heated and thereafter a second precursor of a molecular precursor of a Group IV element or a molecular precursor of a Group VI element that is different from the first is added. The reaction mixture is then mixed to initiate nucleation of IV-VI nanocrystals and the temperature of the reaction mixture is controlled to provide nanoparticles having a diameter of about 20 nm or less.
FILED Monday, November 22, 2004
APPL NO 10/994944
ART UNIT 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry of inorganic compounds
423/508
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US 07208136 Holladay et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jamelyn D. Holladay (Kennewick, Washington);  Yong Wang (Richland, Washington);  Jianli Hu (Kennewick, Washington);  Ya-Huei Chin (Richland, Washington);  Robert A. Dagle (Richland, Washington);  Guanguang Xia (Pasco, Washington);  Eddie G. Baker (Pasco, Washington);  Daniel R. Palo (Kennewick, Washington);  Max R. Phelps (Richland, Washington);  Heon Jung (Taejon, South Korea)
ABSTRACT The present invention provides steam reforming catalyst compositions containing Pd and Zn, and methods of steam reforming alcohols over a catalyst. Surprisingly superior results and properties of the present invention, including low temperature activity and/or low carbon monoxide output, are also described. Methods of making a steam reforming catalyst are also provided.
FILED Friday, May 16, 2003
APPL NO 10/440448
ART UNIT 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry of inorganic compounds
423/652
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208179 Drohan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The American National Red Cross (Rockville, Maryland)
INVENTOR(S) William N. Drohan (Springfield, Virginia);  Martin James MacPhee (Gaithersburg, Maryland);  Jeffrey O. Hollinger (Gibsonia, Pennsylvania)
ABSTRACT This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one oligonucleotide. The composition may be further supplemented with, for example, one or more analgesics, antimicrobial compositions, anticoagulants, antiproliferatives, anti-inflammatory compounds, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like.
FILED Wednesday, June 07, 1995
APPL NO 08/485898
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/549
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208193 Gambino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Research Foundation of the State University of New York (Stony Brook, New York)
INVENTOR(S) Richard Gambino (Stony Brook, New York);  Robert Greenlaw (Huntington Beach, California);  Shaun Kubik (Rocky Point, New York);  Jon Longtin (Port Jefferson, New York);  Joshua Margolies (Niskayuna, New York);  Sanjay Sampath (Setauket, New York)
ABSTRACT A method for direct writing an electrically conductive metallic feature on an insulating substrate comprises creating a gas jet comprising metallic particles (301), ejecting the gas jet comprising metallic particles through a straight bore tube (302), and impacting the gas jet comprising metallic particles onto a substrate to impinge the metallic particles on the substrate to form the electrically conductive metallic feature (303).
FILED Friday, September 26, 2003
APPL NO 10/504343
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating processes
427/98.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208286 Simpson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) UT-Battelle LLC (Oakridge, Tennessee)
INVENTOR(S) Michael L. Simpson (Knoxville, Tennessee);  Michael J. Paulus (Knoxville, Tennessee);  Gary S. Sayler (Blaine, Tennessee);  Bruce M. Applegate (West Lafayette, Indiana);  Steven A. Ripp (Knoxville, Tennessee)
ABSTRACT Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Application Specific Integrated Circuit (OASIC). The microorganism is generally a bacterium.
FILED Tuesday, June 14, 2005
APPL NO 11/152139
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208551 Dang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) University of Dayton (Dayton, Ohio)
INVENTOR(S) Thuy D. Dang (Centerville, Ohio);  Matthew J. Dalton (Xenia, Ohio);  Narayanan Venkatasubramanian (Beavercreek, Ohio);  Joel A. Johnson (Xenia, Ohio);  William A. Feld (Beavercreek, Ohio)
ABSTRACT Polyaryleneetherketone triphenylphosphine oxide compositions incorporating cycloaliphatic units are provided which may be used as a polymeric binders in thermal control coatings for use in space environments. A method is also provided for synthesizing the polyaryleneetherketone triphenylphosphine oxide compositions. A method is also provided for synthesizing the monomeric compositions used to make the polyaryleneetherketone triphenylphosphine oxide compositions.
FILED Wednesday, August 18, 2004
APPL NO 10/920669
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Synthetic resins or natural rubbers
525/216
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US 07208587 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Nanosphere, Inc. (Northbrook, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Robert L. Letsinger (Bloomington, Indiana);  So-Jung Park (Austin, Texas)
ABSTRACT The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids.
FILED Wednesday, August 13, 2003
APPL NO 10/640618
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208612 Bassler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Princeton University (Princeton, New Jersey)
INVENTOR(S) Bonnie L. Bassler (Princeton, New Jersey);  Stephan Schauder (Lyons, France);  Xin Chen (Edison, New Jersey);  Frederick M. Hughson (Princeton, New Jersey);  Stephen R. Cooper (Carlsbad, California)
ABSTRACT A crystal comprising LuxP is obtained, and a binding site for autoinducer-2 (AI-2) identified. The X-ray crystallographic data for LuxP and a LuxP-AI-2 complex is determined and used in a drug discovery method. Pharmaceutical compositions comprising ligands identified by such drug discovery methods are used to treat bacterial infections.
FILED Thursday, August 22, 2002
APPL NO 10/227400
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/213
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US 07208753 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ming Yang (Silver Spring, Maryland);  Chia-Hung Yang (Silver Spring, Maryland);  Yuli Lyanda-Geller (West Lafayette, Indiana)
ABSTRACT A transistor having a bottom dielectric layer, a first layer, a second layer, a top dielectric layer, and a gate electrode. The first layer and the second layer form a composite quantum well between the bottom dielectric layer and the top dielectric layer. The first layer, the second layer, and the top dielectric layer are configured to form a hole wire in the first layer. The gate electrode is over a portion of the hole wire and divides the top dielectric layer into a source contact and a drain contact.
FILED Friday, February 24, 2006
APPL NO 11/307830
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208836 Manning
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Monte Manning (Kuna, Idaho)
ABSTRACT A semiconductor processing method of forming a plurality of conductive lines includes, a) providing a substrate; b) providing a first conductive material layer over the substrate; c) providing a first insulating material layer over the first conductive layer; d) etching through the first insulating layer and the first conductive layer to the substrate to both form a plurality of first conductive lines from the first conductive layer and provide a plurality of grooves between the first lines, the first lines being capped by first insulating layer material, the first lines having respective sidewalls; e) electrically insulating the first line sidewalls; and f) after insulating the sidewalls, providing the grooves with a second conductive material to form a plurality of second lines within the grooves which alternate with the first lines. Integrated circuitry formed according to the method, and other methods, is also disclosed.
FILED Tuesday, August 26, 2003
APPL NO 10/648886
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/758
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209094 Hunter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) James R. Hunter (Waltham, Massachusetts);  Richard J. Barton (Arlington, Massachusetts);  Teresa H. O'Donnell (Billerica, Massachusetts);  Terence W. Bullett (Berthoud, Colorado);  Steven R. Best (Townsend, Massachusetts)
ABSTRACT The Genetically Optimized Digital Ionospheric Sounding System (DISS) Transmit Antenna is a low-cost modification to the TCI 613F HF communications antenna that increases and stabilizes vertical gain from 4 to 30 MHz. Genetic algorithm and local search techniques were used in the design of the modification in order to take into account both electrical design and mechanical simplicity in this design. The novelty lies in the specific placement of conducting wires with respect to the original TCI antenna. This placement both increases the vertical gain of the antenna as a whole and adds to its stability as each wire also acts as a guy cable.
FILED Friday, August 05, 2005
APPL NO 11/198413
ART UNIT 2821 — Electrical Circuits and Systems
CURRENT CPC
Communications: Radio wave antennas
343/874
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209240 Carreiro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Louis G. Carreiro (Westport, Massachusetts);  Lawrence J. Reinhart (Wilmington, Massachusetts)
ABSTRACT A specialized containment cell with optically transparent apertures, in conjunction with a laser interferometer system provides the means for non-contact displacement measurements of electro-active (piezoelectric and electrostrictive) materials to be performed under controlled conditions of pressure, temperature and applied voltage. A sample of electro-active material is placed inside the cell. Electrical connections are made from a high voltage power source to the sample through the cell. Thermoelectric heaters/coolers and a cooling water heat sink built into the cell control the temperature of the sample. The cell is flooded with a dielectric oil pressurizing the interior of the cell to a desired pressure. The cell is optically aligned to the interferometer, and with the cell heated to the proper temperature, a voltage is applied to the sample as the interferometer measures the displacement of the sample.
FILED Thursday, August 05, 2004
APPL NO 10/914777
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/498
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209408 Stottlemyer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) United States of America represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thomas R. Stottlemyer (Mystic, Connecticut);  Tracey Acquaro-Paes (Exeter, Rhode Island);  Michael P. Rousseau (Portsmouth, Rhode Island)
ABSTRACT A towed active acoustic system includes a plurality of soft-bodied, towable, active acoustic modules. The plurality of active acoustic modules are suspended at various depths within the water column, and allow each active acoustic module to be much smaller than known soft-bodied systems and to operate at a much lower source level while still ensuring that the entire water column is ensonified. Each active acoustic module may include different numbers of transducers depending on the intended location of the active acoustic module relative to the water column. The tow cable preferably includes a faired body designed to minimize hydrodynamic drag and turbulence. The present system can be deployed and recovered through shipboard undersurface deployment tubes.
FILED Thursday, October 07, 2004
APPL NO 10/963003
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/154
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209454 Beshai
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Nortel Networks Limited (, Canada)
INVENTOR(S) Maged E. Beshai (Stittsville, Canada)
ABSTRACT An optical channel switch comprising independent optical space switches interconnects electronic data-switch modules to form a high-capacity wide-coverage network. The optical channel switch connects incoming wavelength-division-multiplexed (WDM) links each originating from a data-switch module to outgoing WDM links each terminating in a data-switch module. The optical space switches are of equal dimension, each having the same number of dual ports (input-output ports). The channels of incoming WDM links are assigned to the input ports of the space switches and the output ports of the space switches are assigned to channels of the outgoing WDM links in a manner which permits a switched path from any data-switch module to any other data-switch module even when the number of data-switch modules substantially exceeds the number of dual ports per space switch. A method of reconfiguring the channel switch in response to varying traffic demand is also disclosed.
FILED Wednesday, April 09, 2003
APPL NO 10/409197
ART UNIT 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Multiplex communications
370/254
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209788 Nicolelis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Miguel A. L. Nicolelis (Chapel Hill, North Carolina);  John K. Chapin (Atlantic Beach, New York);  Johan Wessberg (Gothenburg, Sweden)
ABSTRACT A closed loop brain-machine interface is disclosed. The closed loop brain-machine interface translates one or more neural signals into a movement, or a series of movements, performed by a machine. The close-loop brain-machine interface also provides sensory feedback to the subject. Methods of employing the closed loop brain-machine interface are also disclosed.
FILED Monday, October 29, 2001
APPL NO 10/012012
ART UNIT 3766 — Selective Visual Display Systems
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/48
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209831 Hilliard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Donald P. Hilliard (Camarillo, California);  Glenda E. Hilliard (Camarillo, California);  Michael P. Hilliard (Camarillo, California);  Christina A. Hilliard (Camarillo, California)
ABSTRACT A GPS collision avoidance apparatus which uses Global Positioning System (GPS) information and computer processing to determine the location of man made and natural occurring obstacles to allow a user to avoid a collision with these obstacles. The collision avoidance apparatus has a collision decision processor which analyzes position and motion dynamics data including a direction of motion, a velocity and an acceleration for a user utilizing collision avoidance apparatus to determine whether a collision will occur and then to provide protection for the user in the event a collision is likely to occur.
FILED Monday, December 29, 2003
APPL NO 10/746893
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/301
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07210112 DeHon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) André  DeHon (Pasadena, California);  Michael Wrighton (Pasadena, California)
ABSTRACT A method and a device for performing placement of a plurality of elements for circuit design. A potential location is assigned to each element and a placement engine is assigned to each potential location. Pairing operations are performed, in parallel, between placement engines to determine whether to perform exchange of the elements associated with the engines. Exchange determination is based both on a cost function and on randomness considerations. Also self-placement is allowed, where the placement engines are implemented on the same hardware system on which the elements are to be placed.
FILED Monday, August 18, 2003
APPL NO 10/643772
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/9
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07208121 Peper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Auburn University (Auburn, Alabama)
INVENTOR(S) Shane Peper (Los Alamos, New Mexico);  Yu Qin (Auburn, Alabama);  Eric Bakker (Auburn, Alabama)
ABSTRACT A plasticizer-free ion detective sensor for detecting a target ion in a sample is provided. The sensor comprises a copolymer of methacrylate monomers with pendant alkyl groups of different length, and an ionophore for detecting the target ion. The copolymer matrix of the present invention may be in a form of membrane or particles. The sensors of the present invention may be Carrier-based ion-selective electrodes (ISEs) or optodes such as thin film ion-specific optodes or particle-based optodes. The ionophore may be a target ionophore selective for a target ion H+, Li+, Na+, K+, Ca2+, or Mg2+. The ion detective sensor of the present invention may further include an ion exchanger such as halogenated carboranes. Also provided is an ion detective sensor comprising halogenated carboranes as ion exchangers. Particularly, trimethylammonium-2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 undecabromocarborane (TMAUBC) is used as ion exchangers.
FILED Thursday, December 05, 2002
APPL NO 10/313090
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/82.30
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208132 Bolskar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) TDA Research, Inc. (Wheat Ridge, Colorado)
INVENTOR(S) Robert D. Bolskar (Boulder, Colorado);  J. Michael Alford (Lakewood, Colorado)
ABSTRACT The invention provides a method of separating a first and a second set of fullerenes in a fullerene mixture. In the method of the invention, a stable fullerene cation is formed of one of the first or the second set of fullerenes. The fullerene cation is then separated from the other set of fullerenes. Optionally, the fullerene cation may be returned to its neutral state. The method of the invention is particularly useful for the purification and separation of endohedral fullerenes from empty fullerenes. However, the method may be applied to the purification of a broad range of endohedral and empty fullerene materials.
FILED Tuesday, October 01, 2002
APPL NO 10/263374
ART UNIT 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry of inorganic compounds
423/461
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US 07208149 Center et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) David M. Center (Wellesley Hills, Massachusetts);  William W. Cruikshank (Westford, Massachusetts);  Hardy Kornfeld (Wellesley Hills, Massachusetts)
ABSTRACT The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The present invention has demonstrated that such IL-16-inhibiting peptides can be as short as 4 amino acids in length. Based on these discoveries, the present invention provides IL-16 antagonist peptides and the use thereof for the treatment of IL-16 mediated disorders such as certain inflammatory diseases.
FILED Wednesday, February 05, 2003
APPL NO 10/358627
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/85.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208154 Holoshitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Joseph Holoshitz (Ann Arbor, Michigan);  Song Ling (Ypsilanti, Michigan)
ABSTRACT The present invention relates to methods and compositions for counteracting and reversing disease-causing signaling defects in disorders with underlying signal transduction aberrations, including but not limited to rheumatoid arthritis.
FILED Thursday, May 13, 2004
APPL NO 10/845407
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/178.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208161 Murphy et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Brian R. Murphy (Bethesda, Maryland);  Peter L. Collins (Rockville, Maryland);  Anna P. Durbin (Germantown, Maryland);  Mario H. Skiadopoulos (Potomac, Maryland);  Tao Tao (Bethesda, Maryland)
ABSTRACT Isolated polynucleotide molecules provide recombinant PIV genomes and antigenomes for production of recombinant PIV vaccines. The recombinant genome or antigenome can be expressed with a nucleoprotein (N), phosphoprotein (P), and a large (L) polymerase protein to produce isolated infectious PIV particles. The recombinant PIV genome and antigenome can be modified to produce desired changes, for example to incorporate attenuating mutations from biologically derived PIV mutants or to create chimeric PIV clones, to generate attenuated, immunogenic viruses for vaccine use.
FILED Friday, May 22, 1998
APPL NO 09/083793
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/211.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208171 Messersmith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Phillip B. Messersmith (Clarendon Hills, Illinois);  Bi-Huang Hu (Chicago, Illinois);  Marsha Ritter Jones (Chicago, Illinois)
ABSTRACT The invention is related to biomimetic gels that are prepared enzymatically, using a transglutaminase to cross-link polymer-peptide conjugates of rational design.
FILED Friday, October 31, 2003
APPL NO 10/699584
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/422
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208288 Broderick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Joseph P. Broderick (Cincinnati, Ohio);  Joseph F. Clark (Cincinnati, Ohio);  Daniel Woo (Cincinnati, Ohio)
ABSTRACT Methods for enhancing the lysis of coagulated blood comprise administering to coagulated blood a combination of clot clysis agent and a lysis enhancing amount of apolipoprotein E2 (Apo E2) or a therapeutic derivative thereof. Methods for reducing the risk of blood coagulation comprise administering to blood a combination of a clot lysis agent and a lysis enhancing amount of Apo E2 or a therapeutic derivative thereof. Additional methods for enhancing the lysis of coagulated blood comprise administering to an individual a specific level of clot lysis agent wherein the specific level is based upon the apolipoprotein phenotype of the individual. Further methods for reducing the risks of blood coagulation comprise administering to blood a specific level of a clot lysis agent wherein the specific level is based upon the apolipoprotein phenotype of the individual.
FILED Friday, October 12, 2001
APPL NO 10/398880
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208313 McCart et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) J. Andrea McCart (Toronto, Canada);  David L. Bartlett (Pittsburgh, Pennsylvania);  Bernard Moss (Bethesda, Maryland)
ABSTRACT A composition of matter comprising a vaccinia virus expression vector with a negative thymidine kinase phenotype and a negative vaccinia virus growth factor phenotype.
FILED Tuesday, November 13, 2001
APPL NO 09/991721
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208315 Miller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S) Arthur Dusty Miller (Seattle, Washington);  James M. Allen (Seattle, Washington);  Christine L. Halbert (Bothell, Washington)
ABSTRACT The present invention provides packaging cell lines for the efficient production of an Adeno-associated virus (AAV) vector which does not require “helper” virus function for the replication and encapsidation of the AAV vector particles. Packaging cells, methods for their production and methods for producing recombinant AAV vector particles useful for human gene therapy are provided.
FILED Friday, January 05, 2001
APPL NO 10/169785
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208317 Threadgill et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) David W. Threadgill (Chapel Hill, North Carolina);  Daekee Lee (Chapel Hill, North Carolina)
ABSTRACT Cellular libraries useful for in vitro phenotyping and gene mapping. In a representative approach, a method for preparing a homozygous cellular library includes the steps of providing a heterozygous cellular library comprising a plurality of isolated parent cells; inducing site-specific mitotic recombination in the plurality of isolated parent cells; culturing the plurality of isolated parent cells, whereby a population of daughter cells is produced; and selecting daughter cells comprising a homozygous genetic modification, whereby a homozygous cellular library is prepared.
FILED Friday, May 02, 2003
APPL NO 10/428977
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208475 Castillo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Gerardo Castillo (Bothell, Washington);  Alan D. Snow (Lynnwood, Washington)
ABSTRACT A pharmaceutical composition comprising peptide HA3G76 Tyr-Leu-Ser-Lys-Gly-Arg-Leu-Val-Phe-Ala-Leu-Gly (SEQ ID NO:8).
FILED Thursday, September 02, 2004
APPL NO 10/933206
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208478 Carson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dennis A. Carson (Del Mar, California);  Eyal Raz (Del Mar, California);  Mark Roman (San Diego, California)
ABSTRACT Immunostimulatory polynucleotide-immunomodulatory molecule conjugate compositions are disclosed. These compositions include a polynucleotide that is linked to an immunomodulatory molecule, which molecule comprises an antigen and may further comprise immunomodulators such as cytokines and adjuvants. The polynucleotide portion of the conjugate includes at least one immunostimulatory oligonucleotide nucleotide sequence (ISS). Methods of modulating an immune response upon administration of the polynucleotide-immunomodulatory conjugate preparation to a vertebrate host are also disclosed.
FILED Thursday, March 20, 2003
APPL NO 10/394387
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208581 Zapata et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Burnham Institute (La Jolla, California)
INVENTOR(S) Juan M. Zapata (San Diego, California);  John C. Reed (Rancho Santa Fe, California)
ABSTRACT In accordance with the present invention, there are provided novel TRAF-Protein-Binding-Domain polypeptides (TPBDs). The invention also provides nucleic acid molecules encoding TPBDs, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention TPBDs. Such TPBDs and/or anti-TPBD antibodies are useful for discovery of drugs that suppress autoimmunity, inflammation, allergy, allograph rejection, sepsis, and other diseases.
FILED Friday, November 03, 2000
APPL NO 09/706325
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208587 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Nanosphere, Inc. (Northbrook, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Robert L. Letsinger (Bloomington, Indiana);  So-Jung Park (Austin, Texas)
ABSTRACT The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids.
FILED Wednesday, August 13, 2003
APPL NO 10/640618
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208595 Pei
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S) Dehua Pei (Columbus, Ohio)
ABSTRACT A macrocyclic peptide deformylase (PDF) inhibitor comprising a peptide or peptide mimetic having three residues, P1′, P2′, and P3′, wherein P2′ connects P1′ and P3′, wherein P1′ and P3′ each have a side chain, and wherein the side chains on P1′ and P3′ are crosslinked to form the macrocyclic PDF inhibitor. The side chains of P1′ and P3′ interact with the PDF active site, and preferably, P2′ has a side chain that interacts with a solvent. Also provided are methods of inhibiting the growth of a bacterium, the methods comprising contacting the bacterium with an anti-bacterial effective amount of the inventive macrocyclic PDF inhibitor. Additionally, a method of treating a bacterial infection in a subject comprising administering an effective amount of a macrocyclic PDF inhibitor to a subject in need of treatment. Additionally, methods of preparing macrocyclic PDF inhibitors comprising a) choosing an acyclic base molecule, having at least some PDF inhibitory activity, the acyclic base molecule having a first residue having a first side chain that interacts with the PDF active site and a second residue having a second that interacts with the PDF active site; and b) crosslinking the first side chain and the second side chain to form a macrocyclic PDF inhibitor.
FILED Monday, July 26, 2004
APPL NO 10/899207
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
540/460
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208612 Bassler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Princeton University (Princeton, New Jersey)
INVENTOR(S) Bonnie L. Bassler (Princeton, New Jersey);  Stephan Schauder (Lyons, France);  Xin Chen (Edison, New Jersey);  Frederick M. Hughson (Princeton, New Jersey);  Stephen R. Cooper (Carlsbad, California)
ABSTRACT A crystal comprising LuxP is obtained, and a binding site for autoinducer-2 (AI-2) identified. The X-ray crystallographic data for LuxP and a LuxP-AI-2 complex is determined and used in a drug discovery method. Pharmaceutical compositions comprising ligands identified by such drug discovery methods are used to treat bacterial infections.
FILED Thursday, August 22, 2002
APPL NO 10/227400
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/213
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208628 Todd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Kansas State University Research Foundation (Manhattan, Kansas)
INVENTOR(S) Scott C. Todd (Manhattan, Kansas);  Paul W. Baures (Manhattan, Kansas)
ABSTRACT This invention relates to methods and compositions directed towards the diagnosis and treatment of Hepatitis C virus infection and the screening of potential therapeutic compounds using novel small molecules based on imidazole-4,5-dicarboxylic acids scaffolds.
FILED Monday, May 13, 2002
APPL NO 10/144294
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
564/123
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208630 Blagg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Brian Blagg (Lawrence, Kansas);  Gang Shen (Lawrence, Kansas);  Randell C. Clevenger (Eudora, Kansas)
ABSTRACT Novel compounds useful for inhibiting the 90 kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.
FILED Wednesday, October 27, 2004
APPL NO 10/976082
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
564/161
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209535 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Guang-Hong Chen (Madison, Wisconsin);  Charles A. Mistretta (Madison, Wisconsin)
ABSTRACT A generalized projection-slice theorem for divergent beam projections is disclosed. The theorem results in a method for processing the Fourier transform of the divergent beam projections at each view acquired by a CT system to the Fourier transform of the object function. Using this method, an inverse Fourier transform may be used to reconstruct tomographic images from the acquired divergent beam projections.
FILED Friday, June 04, 2004
APPL NO 10/861579
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209588 Liang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
APPLICANT(S)
ASSIGNEE(S) Clever Sys, Inc. (Reston, Virginia)
INVENTOR(S) Yiqing Liang (Vienna, Virginia);  Vikrant Kobla (Ashburn, Virginia);  Xuesheng Bai (Reston, Virginia);  Yi Zhang (Fairfax, Virginia)
ABSTRACT In general, the present invention is directed to systems and methods for finding the position and shape of an animal using video. The invention includes a system with a video camera coupled to a computer in which the computer is configured to automatically provide animal segmentation and identification, animal motion tracking (for moving animals), animal-posture classification, and behavior identification. In a preferred embodiment, the present invention may use background subtraction for animal identification and tracking, and a combination of decision tree classification and rule-based classification for posture and behavior identification. Thus, the present invention is capable of automatically monitoring a video image to identify, track and classify the actions of various animals and the animal's movements within the image. The image may be provided in real time or from storage. The invention is particularly useful for monitoring and classifying animal behavior for testing drugs and genetic mutations, but may be used in any of a number of other surveillance applications.
FILED Thursday, October 30, 2003
APPL NO 10/698044
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/181
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209788 Nicolelis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Miguel A. L. Nicolelis (Chapel Hill, North Carolina);  John K. Chapin (Atlantic Beach, New York);  Johan Wessberg (Gothenburg, Sweden)
ABSTRACT A closed loop brain-machine interface is disclosed. The closed loop brain-machine interface translates one or more neural signals into a movement, or a series of movements, performed by a machine. The close-loop brain-machine interface also provides sensory feedback to the subject. Methods of employing the closed loop brain-machine interface are also disclosed.
FILED Monday, October 29, 2001
APPL NO 10/012012
ART UNIT 3766 — Selective Visual Display Systems
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/48
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209796 McKinney et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
INVENTOR(S) Walter G. McKinney (Morgantown, West Virginia);  Jeff S. Reynolds (Morgantown, West Virginia);  Kimberly A. Friend (Leesburg, Virginia);  William T. Goldsmith (Masontown, West Virginia);  David G. Frazer (Fairmont, West Virginia)
ABSTRACT According to a disclosed embodiment, an auscultatory training apparatus includes a database of pre-recorded physiological sounds stored on a computer for playing on a playback system. A user-friendly, graphical user interface software program is stored on the computer for use with a conventional computer mouse. The program allows a user to select one of the pre-recorded sounds for playback. In addition, the program is operable to generate an inverse model of the playback system in the form of a digital filter. If employed by the user, the inverse model processes the selected sound to cancel the distortions of the playback system so that the sound is accurately reproduced in the playback system. The program also permits the extraction of a specific sound component from a pre-recorded sound so that only the extracted sound component is audible during playback.
FILED Monday, April 29, 2002
APPL NO 10/135964
ART UNIT 2615 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Data processing: Generic control systems or specific applications
7/94
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07207102 Roesler et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Alexander W. Roesler (Tijeras, New Mexico);  Todd R. Christenson (Albuquerque, New Mexico)
ABSTRACT Methods are provided for forming a plurality of permanent magnets with two different north-south magnetic pole alignments for use in microelectromechanical (MEM) devices. These methods are based on initially magnetizing the permanent magnets all in the same direction, and then utilizing a combination of heating and a magnetic field to switch the polarity of a portion of the permanent magnets while not switching the remaining permanent magnets. The permanent magnets, in some instances, can all have the same rare-earth composition (e.g. NdFeB) or can be formed of two different rare-earth materials (e.g. NdFeB and SmCo). The methods can be used to form a plurality of permanent magnets side-by-side on or within a substrate with an alternating polarity, or to form a two-dimensional array of permanent magnets in which the polarity of every other row of the array is alternated.
FILED Thursday, April 01, 2004
APPL NO 10/817007
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/607
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207206 Pinnaduwage et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Lal A. Pinnaduwage (Knoxville, Tennessee);  Thomas G. Thundat (Knoxville, Tennessee);  Gilbert M. Brown (Knoxville, Tennessee);  John Eric Hawk (Olive Branch, Mississippi);  Vassil I. Boiadjiev (Knoxville, Tennessee)
ABSTRACT A chemically functionalized cantilever system has a cantilever coated on one side thereof with a reagent or biological species which binds to an analyte. The system is of particular value when the analyte is a toxic chemical biological warfare agent or an explosive.
FILED Wednesday, February 16, 2005
APPL NO 11/059170
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/23.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207228 Wang
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Duo Wang (Albany, California)
ABSTRACT A method and apparatus for measuring fluid flow in a duct is disclosed. The invention uses a novel high velocity tracer injector system, an optional insertable folding mixing fan for homogenizing the tracer within the duct bulk fluid flow, and a perforated hose sampling system. A preferred embodiment uses CO2 as a tracer gas for measuring air flow in commercial and/or residential ducts. In extant commercial buildings, ducts not readily accessible by hanging ceilings may be drilled with readily plugged small diameter holes to allow for injection, optional mixing where desired using a novel insertable foldable mixing fan, and sampling hose.
FILED Wednesday, August 11, 2004
APPL NO 10/917161
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/861.70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07207396 Hall et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) IntelliServ, Inc. (Provo, Utah)
INVENTOR(S) David R. Hall (Provo, Utah);  David S. Pixton (Lehl, Utah);  Monte L. Johnson (Orem, Utah);  David B. Bartholomew (Springville, Utah);  Joe Fox (Spanish Fork, Utah)
ABSTRACT A method and apparatus for use in assessing down-hole drilling conditions are disclosed. The apparatus includes a drill string, a plurality of sensors, a computing device, and a down-hole network. The sensors are distributed along the length of the drill string and are capable of sensing localized down-hole conditions while drilling. The computing device is coupled to at least one sensor of the plurality of sensors. The data is transmitted from the sensors to the computing device over the down-hole network. The computing device analyzes data output by the sensors and representative of the sensed localized conditions to assess the down-hole drilling conditions. The method includes sensing localized drilling conditions at a plurality of points distributed along the length of a drill string during drilling operations; transmitting data representative of the sensed localized conditions to a predetermined location; and analyzing the transmitted data to assess the down-hole drilling conditions.
FILED Monday, June 28, 2004
APPL NO 10/878243
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Boring or penetrating the earth
175/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208269 Bavykin et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) U Chicago Argonne LLC (Chicago, Illinois)
INVENTOR(S) Sergei Bavykin (Darien, Illinois);  Andrei D. Mirzabekov (Moscow, Russian Federation)
ABSTRACT A method for fragmenting and labeling nucleic acids is provided. The method comprises maintaining double- and single-stranded nucleic acid molecules in an aerobic or an anaerobic atmosphere, contacting the molecules with hydrogen peroxide and radical generating coordination complexes for a time and at concentrations sufficient to produce aldehyde moieties on the molecules, reacting the aldehyde moieties with amine to produce a condensation product, and labeling the condensation product.
FILED Wednesday, January 23, 2002
APPL NO 10/057753
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208286 Simpson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) UT-Battelle LLC (Oakridge, Tennessee)
INVENTOR(S) Michael L. Simpson (Knoxville, Tennessee);  Michael J. Paulus (Knoxville, Tennessee);  Gary S. Sayler (Blaine, Tennessee);  Bruce M. Applegate (West Lafayette, Indiana);  Steven A. Ripp (Knoxville, Tennessee)
ABSTRACT Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Application Specific Integrated Circuit (OASIC). The microorganism is generally a bacterium.
FILED Tuesday, June 14, 2005
APPL NO 11/152139
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209500 Dane et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Metal Improvement Company, LLC (Paramus, New Jersey)
INVENTOR(S) C. Brent Dane (Livermore, California);  Lloyd Hackel (Livermore, California);  Fritz B. Harris (Rocklin, California)
ABSTRACT A laser system, such as a master oscillator/power amplifier system, comprises a gain medium and a stimulated Brillouin scattering SBS mirror system. The SBS mirror system includes an in situ filtered SBS medium that comprises a compound having a small negative non-linear index of refraction, such as a perfluoro compound. An SBS relay telescope having a telescope focal point includes a baffle at the telescope focal point which blocks off angle beams. A beam splitter is placed between the SBS mirror system and the SBS relay telescope, directing a fraction of the beam to an alternate beam path for an alignment fiducial. The SBS mirror system has a collimated SBS cell and a focused SBS cell. An adjustable attenuator is placed between the collimated SBS cell and the focused SBS cell, by which pulse width of the reflected beam can be adjusted.
FILED Wednesday, January 28, 2004
APPL NO 10/766635
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/21
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209545 Radley et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) X-Ray Optical Systems, Inc. (East Greenbush, New York)
INVENTOR(S) Ian Radley (Glenmont, New York);  Thomas J. Bievenue (Delmar, New York);  John H. Burdett, Jr. (Charlton, New York);  Brian W. Gallagher (Guilderland, New York);  Stuart M. Shakshober (Hudson, New York);  Zewu Chen (Schenectady, New York);  Michael D. Moore (Alplaus, New York)
ABSTRACT An x-ray source assembly (2700) and method of operation are provided having enhanced output stability. The assembly includes an anode (2125) having a source spot upon which electrons (2120) impinge and a control system (2715/2720) for controlling position of the anode source spot relative to an output structure. The control system can maintain the anode source spot location relative to the output structure (2710) notwithstanding a change in one or more operating conditions of the x-ray source assembly. One aspect of the disclosed invention is most amenable to the analysis of sulfur in petroleum-based fuels.
FILED Thursday, June 03, 2004
APPL NO 10/859901
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/137
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209579 Weisenberger et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Jefferson Solence Ass. LLC (Newport News, Virginia)
INVENTOR(S) Andrew G. Weisenberger (Yorktown, Virginia);  Stanislaw Majewski (Grafton, Virginia);  Michael J. Paulus (Knoxville, Tennessee);  Shaun S. Gleason (Knoxville, Virginia)
ABSTRACT A novel functional imaging system for use in the imaging of unrestrained and non-anesthetized small animals or other subjects and a method for acquiring such images and further registering them with anatomical X-ray images previously or subsequently acquired. The apparatus comprises a combination of an IR laser profilometry system and gamma, PET and/or SPECT, imaging system, all mounted on a rotating gantry, that permits simultaneous acquisition of positional and orientational information and functional images of an unrestrained subject that are registered, i.e. integrated, using image processing software to produce a functional image of the subject without the use of restraints or anesthesia. The functional image thus obtained can be registered with a previously or subsequently obtained X-ray CT image of the subject. The use of the system described herein permits functional imaging of a subject in an unrestrained/non-anesthetized condition thereby reducing the stress on the subject and eliminating any potential interference with the functional testing that such stress might induce.
FILED Tuesday, January 14, 2003
APPL NO 10/341715
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209861 Hively
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle LLC (Oak Ridge, Tennessee)
INVENTOR(S) Lee M. Hively (Philadelphia, Tennessee)
ABSTRACT This disclosed invention concerns improvements in forewarning of critical events via phase-space dissimilarity analysis of data from mechanical devices, electrical devices, biomedical data, and other physical processes. First, a single channel of process-indicative data is selected that can be used in place of multiple data channels without sacrificing consistent forewarning of critical events. Second, the method discards data of inadequate quality via statistical analysis of the raw data, because the analysis of poor quality data always yields inferior results. Third, two separate filtering operations are used in sequence to remove both high-frequency and low-frequency artifacts using a zero-phase quadratic filter. Fourth, the method constructs phase-space dissimilarity measures (PSDM) by combining of multi-channel time-serial data into a multi-channel time-delay phase-space reconstruction. Fifth, the method uses a composite measure of dissimilarity (Ci) to provide a forewarning of failure and an indicator of failure onset.
FILED Monday, September 22, 2003
APPL NO 10/667045
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/183
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP17646 Abrahamson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Albany, New York)
INVENTOR(S) Lawrence P. Abrahamson (Marcellus, New York);  Richard F. Kopp (Marietta, New York);  Lawrence B. Smart (Geneva, New York);  Timothy A. Volk (Syracuse, New York)
ABSTRACT A distinct female cultivar of Salix purpurea×Salix miyabeana named ‘Millbrook’, characterized by rapid stem growth producing 9% more woody biomass than one of its parents (‘SX64’) and 2% more biomass than a current production cultivar (‘SV1’). ‘Millbrook’ produced greater than 2-fold more stem biomass than two other current production cultivars, ‘SX67’ and ‘SX61’. ‘Millbrook’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Millbrook’ displays a low incidence of rust disease.
FILED Thursday, October 06, 2005
APPL NO 11/244636
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/216
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07208437 Renock et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) T/J Technologies, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Devon Renock (Saline, Michigan);  Intae Bae (Wrentham, Massachusetts);  Pu Zhang (Ann Arbor, Michigan);  Timothy K. Sendek (Huntington Woods, Michigan);  Elizabeth Mueller (Westland, Michigan);  Hanwei Lei (Albuquerque, New Mexico)
ABSTRACT A catalyst is synthesized by a method in which a catalytic metal such as platinum or another noble metal is dispersed onto a support member. A transition metal macrocycle is also adsorbed onto the support, and the support is heat treated so as to at least partially pyrolyze the macrocycle and anchor the transition metal to the support. The catalytic metal is alloyed with the transition metal either during the pyrolysis step, or in a separate step. The catalyst has significant utility in a variety of applications including use as an oxygen reduction catalyst in fuel cells.
FILED Thursday, January 13, 2005
APPL NO 11/035172
ART UNIT 1755 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/117
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208612 Bassler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Princeton University (Princeton, New Jersey)
INVENTOR(S) Bonnie L. Bassler (Princeton, New Jersey);  Stephan Schauder (Lyons, France);  Xin Chen (Edison, New Jersey);  Frederick M. Hughson (Princeton, New Jersey);  Stephen R. Cooper (Carlsbad, California)
ABSTRACT A crystal comprising LuxP is obtained, and a binding site for autoinducer-2 (AI-2) identified. The X-ray crystallographic data for LuxP and a LuxP-AI-2 complex is determined and used in a drug discovery method. Pharmaceutical compositions comprising ligands identified by such drug discovery methods are used to treat bacterial infections.
FILED Thursday, August 22, 2002
APPL NO 10/227400
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/213
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208898 Stoecker et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents for Oklahoma State University (Stillwater, Oklahoma)
INVENTOR(S) Chad Andrew Stoecker (Downers Grove, Illinois);  Eduardo Akira Misawa (Stillwater, Oklahoma);  Clyde Everett Goodner, III (Lakeville, Minnesota)
ABSTRACT Method and apparatus for control object manipulation from an initial position to a final position. A jerk control profile describes a near time-optimal jerk trajectory for the control object and includes a sequence of first, second and third sinusoidal pulses of respectively alternating polarity and common absolute magnitude. The area of the second pulse is nominally equal to the combined area of the first and third pulses, and the pulses are preferably symmetric about the respective maximum pulse values. Associated control profiles (control voltage, current, velocity, displacement, etc.) are derived from the jerk control profile. For longer seeks, constant, non-zero jerk segments are inserted into the profile between the pulses, during which control voltage is maintained near saturation. The control object preferably comprises a transducer in a data storage device and the jerk control profile is stored in a memory location of the device.
FILED Wednesday, June 22, 2005
APPL NO 11/158438
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Motive power systems
318/561
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07210025 Uht et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Education and Human Resources (EHR)
Division of Undergraduate Education (DUE)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Augustus K. Uht (Cumberland, Rhode Island);  David Morano (Malden, Massachusetts);  David Kaeli (Medway, Massachusetts)
ABSTRACT A computing device that provides hardware conversion of flow control predicates associated with program instructions executable within the computing device, detects the beginning and the end of a branch domain of the program instructions, and realizes the beginning and the end of the branch domain at execution time, for selectively enabling and disabling instructions within said branch domain.
FILED Thursday, April 19, 2001
APPL NO 09/838678
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/226
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07210112 DeHon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) André  DeHon (Pasadena, California);  Michael Wrighton (Pasadena, California)
ABSTRACT A method and a device for performing placement of a plurality of elements for circuit design. A potential location is assigned to each element and a placement engine is assigned to each potential location. Pairing operations are performed, in parallel, between placement engines to determine whether to perform exchange of the elements associated with the engines. Exchange determination is based both on a cost function and on randomness considerations. Also self-placement is allowed, where the placement engines are implemented on the same hardware system on which the elements are to be placed.
FILED Monday, August 18, 2003
APPL NO 10/643772
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/9
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07207140 Decker
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S) Buckeye Bluegrass Farms, Inc. (Lewis Center, Ohio)
INVENTOR(S) Henry F. Decker (Ostrander, Ohio)
ABSTRACT The invention provides a new form of vegetative propagating material, referred to as “the grass plantlet”, as well as a method for producing it. The new vegetative planting material and the method by which it is obtained make it possible to replicate and increase both warm and cool season grasses more rapidly than by the conventional methods of seeding, sprigging, or plugging. Three to five new, clean, and pure generations of a newly developed seeded or vegetative cultivar can be obtained each year. Outcrossing, the need for burning and possibly for herbicide use are eliminated by the present invention. The present methodology embodies a sterile production system resulting in grass plantlets that are free of nematodes, pathogenic fungi, and damaging insects. The method of the invention has the capacity to rapidly reproduce and to maintain the genetic purity of promising new cultivars that would otherwise be discarded because they are sterile hybrids, low seed producers, sterile direct DNA transfers, or cross pollinated non-apomicts.
FILED Monday, December 29, 2003
APPL NO 10/745516
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Plant husbandry
047/58.1SE
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208181 King et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Jerry W. King (Peoria, Illinois);  Richard D. Grabiel (Decatur, Illinois)
ABSTRACT Anthocyanins, other flavonoids and related polyphenolic compounds are extracted from fruits or highly pigmented garden vegetables and their by-products using subcritical water with or without a secondary cosolvent. This method has the advantages of being relatively inexpensive, minimizes or totally avoids the use of objectionable solvents, and provides a facile means for supplying an ample source of concentrated phytochemicals for use in food formulation, dietary supplements and phyto-pharmaceutical applications.
FILED Wednesday, June 12, 2002
APPL NO 10/171258
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/725
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208303 Loria et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York);  United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Rosemary Loria (Ithaca, New York);  Brian Crane (Ithaca, New York);  Johan Kers (Ithaca, New York);  Donna M. Gibson (Ithaca, New York);  Michael J. Wach (Ithaca, New York)
ABSTRACT The present invention relates to isolated nucleic acid molecules encoding nitric oxide synthases. The isolated nucleic acid molecules and their encoded protein or polypeptides are useful in methods for attaching a nitrogen group to a target moiety of a compound and for synthesizing a nitrogen-modified compound in a transgenic host cell. The present invention also relates to expression systems and host cells containing the nucleic acids of the present invention, as well as a method of recombinantly producing the nitric oxide synthases of the present invention.
FILED Wednesday, June 02, 2004
APPL NO 10/858706
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/191
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208476 Nachman et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Ronald J. Nachman (Willis, Texas);  Peter E. A. Teal (Gainesville, Florida);  Christopher S. Garside (Toronto, Canada);  Stephen S. Tobe (Virgil, Canada)
ABSTRACT Novel pseudopeptide analogs of the insect allatostatin neuropeptide family which possess biological activity mimicking that of the naturally occurring neuropeptides are disclosed. By addition of a hydrophobic moiety to an active portion of the allatostatin peptides, analogs are produced which exhibit an overall amphiphilic nature and which are capable of penetrating the insect cuticle while still retaining biological activity. Furthermore, by substituting sterically hindered amino acids or aromatic acids for any or all of the first, third or fifth amino acid residues of the allatostatin C-terminal pentapeptide, analogs may be produced which are resistant to degradation by insect peptidases while still retaining biological activity. The analogs may be used for insect control by disrupting critical reproductive and/or developmental processes normally regulated by allatostatins in insects.
FILED Wednesday, September 10, 2003
APPL NO 10/659233
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/18
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07208271 Bost et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Applera Corporation (Foster City, California)
INVENTOR(S) Douglas A. Bost (San Mateo, California);  Lawrence Greenfield (San Mateo, California)
ABSTRACT The invention relates to methods for isolating and/or identifying nucleic acids. The invention also provides kits for isolating and/or identifying nucleic acids.
FILED Wednesday, November 27, 2002
APPL NO 10/306347
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208320 Manz et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S)
ASSIGNEE(S) Caliper Life Sciences, Inc. (Mountain View, California)
INVENTOR(S) Andreas Manz (East Molesey, United Kingdom);  Luc J. Bousse (Los Altos, California)
ABSTRACT Microfluidic devices and systems for affecting the serial to parallel conversion of materials introduced into the device or system. Material or materials to be converted from a serial orientation, e.g., a single channel, into a parallel orientation, e.g., multiple channels, are introduced into an open chamber or field in which containing flows of materials maintain the cohesiveness of the sample material plugs serially introduced into the open chamber. The sample material or materials are then redirected in the chamber toward and into a plurality of parallel channels that also communicate with the chamber.
FILED Friday, December 13, 2002
APPL NO 10/318979
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Analytical and immunological testing
436/180
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208437 Renock et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) T/J Technologies, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Devon Renock (Saline, Michigan);  Intae Bae (Wrentham, Massachusetts);  Pu Zhang (Ann Arbor, Michigan);  Timothy K. Sendek (Huntington Woods, Michigan);  Elizabeth Mueller (Westland, Michigan);  Hanwei Lei (Albuquerque, New Mexico)
ABSTRACT A catalyst is synthesized by a method in which a catalytic metal such as platinum or another noble metal is dispersed onto a support member. A transition metal macrocycle is also adsorbed onto the support, and the support is heat treated so as to at least partially pyrolyze the macrocycle and anchor the transition metal to the support. The catalytic metal is alloyed with the transition metal either during the pyrolysis step, or in a separate step. The catalyst has significant utility in a variety of applications including use as an oxygen reduction catalyst in fuel cells.
FILED Thursday, January 13, 2005
APPL NO 11/035172
ART UNIT 1755 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/117
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209223 Hull et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S)
ASSIGNEE(S) Luna Innovations Incorporated (Blacksburg, Virginia)
INVENTOR(S) Matthew S Hull (Dublin, Virginia);  Joshua P Averett (Radford, Virginia);  Mark E Jones (Sequim, Washington);  Daniel R Klemer (Lexington, Kentucky)
ABSTRACT A device and method for measuring optical properties of a sample are provided. The device comprises a housing surrounding a flow-through flow-cell having a sample inlet positioned proximate to a first end of the flow-cell and a sample outlet positioned proximate to a second end of the flow-cell and a sample chamber positioned between the sample inlet and the sample outlet. A plurality of excitation sources are positioned on the housing and are incident on a sample in the flow-cell. At least one excitation source has a wavelength that is different from the other excitation sources. At least one fluorescence emission detector, which detects a continuous broadband spectrum of emission wavelengths, is positioned in an operable relationship to the flow-cell. At least one signal interrogation system, which interprets a continuous fluorescence emission spectrum, is positioned in an operable relationship with each detector.
FILED Monday, November 14, 2005
APPL NO 11/272624
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/73
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07207245 Vranish
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) John M. Vranish (Crofton, Maryland)
ABSTRACT A tool comprises a first handle and a second handle, each handle extending from a gripping end portion to a working end portion, the first handle having first screw threads disposed circumferentially about an inner portion of a first through-hole at the working end portion thereof, the second handle having second screw threads disposed circumferentially about an inner portion of a second through-hole at the working end portion thereof, the first and second respective through-holes being disposed concentrically about a common axis of the working end portions. First and second screw locks preferably are disposed concentrically with the first and second respective through-holes, the first screw lock having a plurality of locking/unlocking screw threads for engaging the first screw threads of the first handle, the second screw lock having a plurality of locking/unlocking screw threads for engaging the second screw threads of the second handle. A locking clutch drive, disposed concentrically with the first and second respective through-holes, engages the first screw lock and the second screw lock. The first handle and the second handle are selectively operable at their gripping end portions by a user using a single hand to activate the first and second screw locks to lock the locking clutch drive for either clockwise rotation about the common axis, or counter-clockwise rotation about the common axis, or to release the locking clutch drive so that the handles can be rotated together about the common axis either the clockwise or counter-clockwise direction without rotation of the locking clutch drive.
FILED Thursday, June 30, 2005
APPL NO 11/174454
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Tools
081/121.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208240 Hartley
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Ionfinity LLC (Pasadena, California)
INVENTOR(S) Frank T. Hartley (Arcadia, California)
ABSTRACT A fuel cell is disclosed comprising an ionization membrane having at least one area through which gas is passed, and which ionizes the gas passing therethrough, and a cathode for receiving the ions generated by the ionization membrane. The ionization membrane may include one or more openings in the membrane with electrodes that are located closer than a mean free path of molecules within the gas to be ionized. Methods of manufacture are also provided.
FILED Thursday, February 26, 2004
APPL NO 10/786232
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07209567 Kozel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) David Kozel (Crown Point, Indiana);  James A. Devault (Pensacola, Florida);  Richard B. Birr (Oviedo, Florida)
ABSTRACT A signal-to-noise ratio dependent adaptive spectral subtraction process eliminates noise from noise-corrupted speech signals. The process first pre-emphasizes the frequency components of the input sound signal which contain the consonant information in human speech. Next, a signal-to-noise ratio is determined and a spectral subtraction proportion adjusted appropriately. After spectral subtraction, low amplitude signals can be squelched. A single microphone is used to obtain both the noise-corrupted speech and the average noise estimate. This is done by determining if the frame of data being sampled is a voiced or unvoiced frame. During unvoiced frames an estimate of the noise is obtained. A running average of the noise is used to approximate the expected value of the noise. Spectral subtraction may be performed on a composite noise-corrupted signal, or upon individual sub-bands of the noise-corrupted signal. Pre-averaging of the input signal's magnitude spectrum over multiple time frames may be performed to reduce musical noise.
FILED Monday, March 10, 2003
APPL NO 10/390259
ART UNIT 2615 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Electrical audio signal processing systems and devices
381/94.300
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07207140 Decker
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S) Buckeye Bluegrass Farms, Inc. (Lewis Center, Ohio)
INVENTOR(S) Henry F. Decker (Ostrander, Ohio)
ABSTRACT The invention provides a new form of vegetative propagating material, referred to as “the grass plantlet”, as well as a method for producing it. The new vegetative planting material and the method by which it is obtained make it possible to replicate and increase both warm and cool season grasses more rapidly than by the conventional methods of seeding, sprigging, or plugging. Three to five new, clean, and pure generations of a newly developed seeded or vegetative cultivar can be obtained each year. Outcrossing, the need for burning and possibly for herbicide use are eliminated by the present invention. The present methodology embodies a sterile production system resulting in grass plantlets that are free of nematodes, pathogenic fungi, and damaging insects. The method of the invention has the capacity to rapidly reproduce and to maintain the genetic purity of promising new cultivars that would otherwise be discarded because they are sterile hybrids, low seed producers, sterile direct DNA transfers, or cross pollinated non-apomicts.
FILED Monday, December 29, 2003
APPL NO 10/745516
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Plant husbandry
047/58.1SE
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07208221 Drzal et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Lawrence T. Drzal (Okemos, Michigan);  Geeta Mehta (Ann Arbor, Michigan);  Manjusri Misra (Lansing, Michigan);  Amar K. Mohanty (Lansing, Michigan);  Kelby Thayer (Leslie, Michigan)
ABSTRACT A Sheet Molding Compound (SMC) as prepregs and cured compositions with naturally derived fibers which have been dried for at least three hours is described. The SMC process combines polyester polymer or resin with the fibers preferably continuously. The molded products are useful for a variety a purposes where glass fiber filled polyester polymers are conventionally used.
FILED Friday, October 15, 2004
APPL NO 10/966988
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Stock material or miscellaneous articles
428/297.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07208467 Krieger et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Monty Krieger (Needham, Massachusetts);  Helena E. Miettinen (Helsinki 96, Finland)
ABSTRACT SR-BI is present at relatively high levels on the membranes of hepatocytes and steroidogenic tissues, including the adrenal gland, testes, and ovaries, where it mediates the uptake and transport of cholesteryl ester from high density lipoproteins. It has been demonstrated that transgenic animals which do not produce SR-BI are healthy, with the exception that the females are infertile. SR-BI KO females have abnormal HDLs, ovulate dysfunctional oocytes and are infertile. Surgical, genetic and pharmacologic methods were used to show that the fertility of SR-BI KO females (or their transplanted oocytes) can be restored in the absence of ovarian and/or extraovarian SR-BI expression by manipulations that modify the structure, composition and/or abundance of their abnormal plasma lipoproteins. These manipulations included inactivation of the apolipoprotein A-I gene and administration of the cholesterol-lowering drug PROBUCOL™. In the absence of treatment, female animals which do not express SR-BI have dramatically reduced levels of offspring, even though they are otherwise healthy and the males normal. Studies demonstrate that they do not produce viable eggs and have a defect involving implantation of normal eggs.
FILED Friday, June 07, 2002
APPL NO 10/164863
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 24, 2007.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2007/fedinvent-patents-20070424.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital