FedInvent™ Patents
Patent Details for Tuesday, May 08, 2007
This page was updated on Sunday, March 26, 2023 at 08:42 PM GMT
Department of Health and Human Services (HHS)
| US 07214372 | Rao et al. |
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| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Mahendra S. Rao (Salt Lake City, Utah); Mark Noble (Brighton, New York); Margot Mayer-Proschel (Pittsford, New York) |
| ABSTRACT | A glial precursor cell population from mammalian central nervous system has been isolated. These A2B5+ E-NCAM− glial-restricted precursor (GRP) cells are capable of differentiating into oligodendrocytes, A2B5+ process-bearing astrocytes, and A2B5− fibroblast-like astrocytes, but not into neurons. GRP cells can be maintained by regeneration in culture. GRP cells differ from oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells in growth factor requirements, morphology, and progeny. Methods of use of GRP cells are also disclosed. |
| FILED | Monday, December 30, 2002 |
| APPL NO | 10/335354 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214373 | Elias et al. |
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| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Jack A. Elias (Woodbridge, Connecticut); Zhou Zhu (Woodbridge, Connecticut) |
| ABSTRACT | The present invention includes compositions and methods for the treatment of inflammatory disease (e.g., asthma, COPD, inflammatory bowel disease, atopic dermatitis, atopy, allergy, allergic rhinitis, scleroderma, and the like), relating to inhibiting a chitinase-like molecule. The invention further includes methods to identify new compounds for the treatment of inflammatory disease, including, but not limited to, asthma, COPD and the like. This is because the present invention demonstrates, for the first time, that expression of IL-13, and of a chitinase-like molecule, mediates and/or is associated with inflammatory disease and that inhibiting the chitinase-like molecule treats and even prevents, the disease. Thus, the invention relates to the novel discovery that inhibiting a chitinase-like molecule treats and prevents an inflammatory disease. |
| FILED | Tuesday, July 23, 2002 |
| APPL NO | 10/202436 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214375 | Border et al. |
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| ASSIGNEE(S) | La Jolla Cancer Research Foundation (La Jolla, California) |
| INVENTOR(S) | Wayne A. Border (Salt Lake City, Utah); Erkki I. Ruoslahti (Ranco Santa Fe, California) |
| ABSTRACT | The present invention provides a method for treating or arresting the progress of pathologies characterized by an accumulation of extracellular matrix components by providing an agent to suppress the activity of transforming growth factor β (TGF-β) a peptide growth factor which is anabolic and leads to fibrosis and angiogenesis. In one embodiment, such agent is anti-TGF-β antibody. Pathologies which can be so treated include, but are not limited to, glomerulonephritis, adult respiratory distress syndrome and cirrhosis of the liver. The invention further provides a method for the diagnosis of pathologies, or incipient pathologies, which are characterized by the accumulation of extracellular matrix components in tissues by determining the levels of TGF-β in the tissues, a high level being indicative of such pathologies. |
| FILED | Friday, December 02, 1994 |
| APPL NO | 08/349479 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/145.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214380 | DeKruyff et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Rosemarie H. DeKruyff (Stanford, California); Dale T. Umetsu (Stanford, California) |
| ABSTRACT | Methods are provided for the treatment of allergic and other immune disorders associated with overproduction of Th2 type cytokines by antigen specific T cells. Immunotherapy with adjuvants, as provided in the present invention, greatly inhibits the development of airway hyperreactivity and airway inflammation. Such immunotherapy is shown to reverse ongoing airway disease, and convert allergic inflammatory responses into protective immune responses. Conditions of particular interest include allergic conditions associated with production of Th2 cytokines and/or IgE antibodies, asthma, allergic rhinitis, and anaphylactic reactions. The addition of adjuvant induces a Th1-type immune response and can redirect an established Th2-type response to a Th1-type response for the selected antigen. Preferably, antigen-specific IgE production is reduced without altering the intensity of the antigen-specific proliferative response. One particularly preferred adjuvant for use in accordance with the present invention is a Listeria adjuvant. |
| FILED | Friday, April 28, 2000 |
| APPL NO | 09/561089 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/275.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214477 | Emmert-Buck |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michael R. Emmert-Buck (Silver Spring, Maryland) |
| ABSTRACT | The present invention involves methods, systems, and devices for analyzing a biological material, such as a cellular or other specimen. The method includes placing the specimen on a substrate having different capture regions, such as contiguous layers, wherein the different capture regions of the substrate contain different identification molecules, and transferring components of the specimen through the capture regions under conditions that allow the components to interact with different identification molecules in the different regions of the substrate. The components of the specimen can be transferred through the different layers (or other regions) of the substrate by capillary action of a solution moving through the cellular specimen or by electrophoresis. The transfer of components of the specimen through the substrate may occur while maintaining a geometric correspondence to the specimen, such as the cytoarchitecture of a cellular specimen, for example by moving the components through parallel layers having positions that correspond to positions within the specimen. When the cellular architecture of the specimen is maintained, a correlation between the different identification molecules and the components of the cellular specimens may be made. The analysis can occur with one or more different discrete (for example cellular) specimens on a surface of the substrate. Examples of cellular specimens include, but are not limited to tissue sections, particularly tumor tissue sections. The cellular specimen can also include cultured cells or a cytology sample. Cytostat tissue sections cut slightly thicker than usual, that is about 25 to about 50 μm, improves the ability to detect molecules of moderate and low level abundance. |
| FILED | Wednesday, July 26, 2000 |
| APPL NO | 10/048194 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214479 | Welch et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Rodney A. Welch (Madison, Wisconsin); Wyndham W. Lathem (St. Louis, Missouri); Thomas E. Grys (Madison, Wisconsin) |
| ABSTRACT | Disclosed is a pO157 plasmid-specified polypeptide found in E. coli EDL933 and other E. coli that binds to and cleaves C1-esterase inhibitor, and antibodies specific for the polypeptide. Also disclosed are methods employing the polypeptide for diagnosing enterohemorrhagic E. coli infection, identifying potential inhibitors of its activity, and reducing viscosity of material containing glycosylated polypeptides. |
| FILED | Wednesday, February 25, 2004 |
| APPL NO | 10/786445 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214482 | Evans et al. |
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| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Bruce Blumberg (Irvine, California) |
| ABSTRACT | A novel nuclear receptor, termed the steroid and xenobiotic receptor (SXR), a broad-specificity sensing receptor that is a novel branch of the nuclear receptor superfamily, has been discovered. SXR forms a heterodimer with RXR that can bind to and induce transcription from response elements present in steroid-inducible cytochrome P450 genes in response to hundreds of natural and synthetic compounds with biological activity, including therapeutic steroids as well as dietary steroids and lipids. Instead of hundreds of receptors, one for each inducing compound, the invention SXR receptors monitor aggregate levels of inducers to trigger production of metabolizing enzymes in a coordinated metabolic pathway. Agonists and antagonists of SXR are administered to subjects to achieve a variety of therapeutic goals dependent upon modulating metabolism of one or more endogenous steroids or xenobiotics to establish homeostasis. An assay is provided for identifying steroid drugs that are likely to cause drug interaction if administered to a subject in therapeutic amounts. Transgenic animals are also provided which express human SXR, thereby serving as useful models for human response to various agents which potentially impact P450-dependent metabolic processes. |
| FILED | Wednesday, February 20, 2002 |
| APPL NO | 10/081555 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214483 | Singh et al. |
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| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Nanda A. Singh (Heber City, Utah); Mark F. Leppert (Salt Lake City, Utah); Carole Charlier (Sprimont, Belgium) |
| ABSTRACT | Generalized idiopathic epilepsies (IGE) cause 40% of all seizures and commonly have a genetic basis. One type of IGE is Benign Familial Neonatal Convulsions (BFNC), a dominantly inherited disorder of newborns. A submicroscopic deletion of chromosome 20q13.3 which co-segregates with seizures in a BFNC family has been identified. Characterization of cDNAs spanning the deleted region identified a novel voltage-gated potassium channel, KCNQ2, which belongs to a new KCNQ1-like class of potassium channels. Nine other BFNC probands were shown to have KCNQ2 mutations including three missense mutations, three frameshifts, two nonsense mutations, and one splice site mutation. A second gene, KCNQ3, was found in a separate BFNC family in which the mutation had been localized to chromosome 8. A missense mutation was found in this gene in perfect cosegregation with the BFNC phenotype in this latter family. This demonstrates that defects in potassium channels can cause epilepsy. Furthermore, some members of one of the BFNC families with a mutation in KCNQ2 also exhibited rolandic epilepsy and one individual with juvenile myoclonic epilepsy has a mutation in an alternative exon of KCNQ3. |
| FILED | Thursday, March 14, 2002 |
| APPL NO | 10/096578 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214485 | Belinsky et al. |
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| ASSIGNEE(S) | Lovelace Respiratory Research Institute (Albuquerque, New Mexico) |
| INVENTOR(S) | Steven A. Belinsky (Albuquerque, New Mexico); William A. Palmisano (Edgewood, New Mexico) |
| ABSTRACT | A molecular marker-based method for monitoring and detecting cancer in humans. Aberrant methylation of gene promoters is a marker for cancer risk in humans. A two-stage, or “nested” polymerase chain reaction method is disclosed for detecting methylated DNA sequences at sufficiently high levels of sensitivity to permit cancer screening in biological fluid samples, such as sputum, obtained non-invasively. The method is for detecting the aberrant methylation of the p16 gene, O 6-methylguanine-DNA methyltransferase gene, Death-associated protein kinase gene, RAS-associated family 1 gene, or other gene promoters. The method offers a potentially powerful approach to population-based screening for the detection of lung and other cancers. |
| FILED | Friday, August 24, 2001 |
| APPL NO | 10/344815 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214488 | Kaye et al. |
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| ASSIGNEE(S) | United States of America, Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Frederic J. Kaye (Potomac, Maryland); Giovanni Tonon (Watertown, Massachusetts) |
| ABSTRACT | The present invention provides methods and compositions for the diagnosis and treatment of cancer, including cancers involving the NOTCH pathway. In particular, the present invention provides methods and compositions for the diagnosis of mucoepidermoid carcinoma, the most common malignant salivary gland tumor. The present invention further provides methods and compositions for the diagnosis of other tumors associated with the t(11;19)(q14–21;12–13) translocation. |
| FILED | Wednesday, July 03, 2002 |
| APPL NO | 10/479546 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214489 | Bazan et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (Santa Barbara, California) |
| ABSTRACT | Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PNA complementary to the target polynucleotide. The sensor PNA comprises a signaling chromophore to absorb energy from the excited multichromophore and emit light in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided. |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600286 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214496 | Oakley et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Robert H. Oakley (Durham, North Carolina); Lawrence S. Barak (Durham, North Carolina); Stephane A. Laporte (Outremont, Canada); Marc G. Caron (Hillsborough, North Carolina) |
| ABSTRACT | The present invention relates to modified G-protein coupled receptors (GPCRs). The modified GPCRs of the present invention include GPCRs that have been modified to have carboxyl terminal tails comprising one or more sites of phosphorylation, preferably one or more clusters of phosphorylation sites. The modified GPCRs of the present invention may comprise a retained portion of a carboxyl-terminus region from a first GPCR fused to a polypeptide, wherein the polypeptide comprises the one or more clusters of phosphorylation. The present invention also relates to methods of screening compounds and sample solutions for GPCR activity using the modified GPCRs. |
| FILED | Thursday, December 30, 2004 |
| APPL NO | 11/026435 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214498 | Nelson et al. |
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| ASSIGNEE(S) | Benaroya Research Institute at Virginia Mason (Seattle, Washington) |
| INVENTOR(S) | Brad H. Nelson (Seattle, Washington); Bradley C. Stone (Seattle, Washington) |
| ABSTRACT | The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease. |
| FILED | Monday, March 25, 2002 |
| APPL NO | 10/106559 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214510 | Stallcup et al. |
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| ASSIGNEE(S) | Regents of the University of California (Oakland, California); The University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Michael R. Stallcup (Los Angeles, California); Dagang Chen (Hacienda Heights, California); Heng Hong (Carlmel, Indiana); Dana W. Aswad (Irvine, California) |
| ABSTRACT | The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine residues of histones, synthetic peptides, and other proteins. A method to use CARM1 to screen for drugs that inhibit its methyltransferase activity is also described, as is a method to screen for drugs that modulate CARM1's interactions with other proteins. |
| FILED | Thursday, April 22, 2004 |
| APPL NO | 10/830591 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/68 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214511 | Evans et al. |
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| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Ronald M. Evans (San Diego, California); Cary A. Weinberger (Silver Spring, Maryland); Stanley M. Hollenberg (San Kiego, California); Estelita S. Ong (San Diego, California) |
| ABSTRACT | In accordance with the present invention, there are provided expression systems for the production of function glucocorticoid receptor proteins, methods for the recombinant production of glucocorticoid receptor proteins as well as sequences encoding novel members of the steroid/thyroid hormone superfamily of receptors (e.g., glucocorticoid receptor). Invention expression systems comprise host cells containing DNA encoding functional glucocorticoid receptor proteins, wherein the DNA is operably linked to control sequences compatible with host cells, thereby enabling the expression of functional receptor proteins. The invention method is carried out by culturing such recombinant host cells, and recovering the functional glucocorticoid receptor proteins produced thereby. In accordance with the present invention, there are also provided substantially pure DNA's comprised of sequences which encode members of the steroid/thyroid hormone receptor superfamily having the hormone-binding and/or transcription-activating characteristics of a glucocorticoid receptor. The invention also provides various plasmids containing receptor sequences which exemplify the DNA's of the invention. The invention further provides receptor proteins, including modified functional forms thereof, expressed from the DNA's (or mRNA's) of the invention. |
| FILED | Monday, June 05, 1995 |
| APPL NO | 08/464262 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214515 | Chiocca et al. |
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| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | E. Antonio Chiocca (Wakefield, Massachusetts); Yoshinaga Saeki (Arlington, Massachusetts); Richard Wade-Martins (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to HSV-based amplicon vectors carrying a genomic DNA fragment, and methods of constructing and using the same. Included within the present invention is a method of converting any large capacity DNA cloning vector, such as a BAC or PAC, into an HSV amplicon or hybrid HSV amplicon using site-specific, or other types of recombination, so that genomic DNA inserts within the BAC or PAC clone can be delivered by infection to a cell, and efficiently expressed. The present invention also relates to a system for the rapid creation of viral vectors carrying transgenes of interest. This aspect of the invention is accomplished through recombination between: (a) a large-capacity cloning vector carrying a viral genome, and (b) a transfer vector containing the transgene of interest. Finally, an expression-ready genomic DNA library is disclosed. |
| FILED | Friday, January 04, 2002 |
| APPL NO | 10/035216 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214519 | Martin et al. |
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| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Emil Martin (Houston, Texas); Ferid Murad (Houston, Texas) |
| ABSTRACT | A method of screening a substance of interest for heme independent modulation of enzymatic activity of soluble guanylyl cyclase (sGC) is disclosed, comprising (a) obtaining αβCys105 mutant sGC enzyme; (b) determining activity of the mutant enzyme for forming cGMP from GTP in the presence of the substance of interest in a reaction medium; (c) determining activity as in step (b), except in the absence of the substance of interest; optionally, (d) including an activator other than the substance of interest in steps b) and c); e) comparing results of (b)–(d) to yield a comparison result; and f) from that value of that result, assessing activity of the substance of interest for modulating cGMP production by the mutant enzyme. Increased or decreased formation of cGMP in the presence of the substance of interest indicates activity of the substance for modulating heme independent cGMP production. |
| FILED | Wednesday, February 11, 2004 |
| APPL NO | 10/777008 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214531 | Ladjevardi et al. |
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| ASSIGNEE(S) | Disan, Inc. (San Diego, California) |
| INVENTOR(S) | Mahmoud Ladjevardi (La Jolla, California); Theodore Sand (Poway, California) |
| ABSTRACT | An assay system has a chamber that receives a test strip onto which a sample comprising an analyte has been placed. The chamber is in gaseous communication with a piezoelectric material that generates an electrical signal in response to a pressure change in the chamber that is caused by a reaction between the analyte and a reagent. |
| FILED | Monday, April 15, 2002 |
| APPL NO | 10/479782 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214534 | Law et al. |
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| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Ping-yee Law (Vadnais Heights, Minnesota); Horace H. Loh (Little Canada, Minnesota); Wanling Yang (Charleston, South Carolina); Xiao-Hong Guo (St. Paul, Minnesota); Patricia A. Geppert (San Antonio, Texas) |
| ABSTRACT | The invention provides genetic approaches to inhibit or treat pain which employ mutant μ opioid receptors. |
| FILED | Wednesday, June 18, 2003 |
| APPL NO | 10/465172 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214545 | Meares et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Claude F. Meares (Davis, California); Paul A. Whetstone (Davis, California); Todd M. Corneillie (Berkeley, California); Nathaniel G. Butlin (Davis, California) |
| ABSTRACT | The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules. More particularly, the invention provides Element Coded Affinity Tags comprising a metal chelate and a metal ion and methods of using the tags to detect, analyze, and identify biomolecules including polypeptides, nucleic acids, lipids, and polysaccharides. |
| FILED | Wednesday, April 28, 2004 |
| APPL NO | 10/835533 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214661 | Carney |
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| ASSIGNEE(S) | OrthoLogic Corp. (Tempe, Arizona) |
| INVENTOR(S) | Darrell H. Carney (Dickinson, Texas) |
| ABSTRACT | The present invention relates to a method for promoting cardiac tissue repair comprising administering to the cardiac tissue a therapeutically effective amount of an angiogenic thrombin derivative peptide and/or inhibiting or reducing vascular occlusion or restenosis. The invention also relates to methods of stimulating revascularization. In yet another embodiment, the invention relates to the use of thrombin derivative peptides in the manufacture of a medicament for the methods described herein. |
| FILED | Friday, December 02, 2005 |
| APPL NO | 11/293495 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214665 | Linden et al. |
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| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Joel M. Linden (Charlottesville, Virginia); Jayson M. Rieger (Charlottesville, Virginia); Timothy L. Macdonald (Charlottesville, Virginia); Gail W. Sullivan (Charlottesville, Virginia); Lauren Jean Murphree (Earlysville, Virginia); Robert Alan Figler (Earlysville, Virginia) |
| ABSTRACT | The invention provides compounds having the following general formula (I): wherein X, R1, R2, R7 and Z are as described here. |
| FILED | Tuesday, October 01, 2002 |
| APPL NO | 10/263379 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214693 | Dalton et al. |
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| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | James T. Dalton (Upper Arlington, Ohio); Duane D. Miller (Germantown, Tennessee) |
| ABSTRACT | This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. The SARM compounds, either alone or as a composition, are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and/or prevention of acute and/or chronic muscular wasting conditions; e) preventing and/or treating dry eye conditions; f) oral androgen replacement therapy; g) decreasing the incidence of, halting or causing a regression of prostate cancer; and/or h) inducing apoptosis in a cancer cell. |
| FILED | Tuesday, October 14, 2003 |
| APPL NO | 10/683125 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/352 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214695 | Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Jeffery W. Kelly (La Jolla, California); Evan T. Powers (La Jolla, California); Hossein Razavi (Danbury, Connecticut) |
| ABSTRACT | Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed. |
| FILED | Friday, December 19, 2003 |
| APPL NO | 10/741649 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214696 | Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Jeffery W. Kelly (LaJolla, California); Yoshiki Sekijima (Matsumoto, Japan) |
| ABSTRACT | Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed. |
| FILED | Friday, October 21, 2005 |
| APPL NO | 11/256026 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214769 | Gutheil et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | William G. Gutheil (Kansas City, Missouri); Qingchai Xu (Sacramento, California) |
| ABSTRACT | The present invention provides a process for preparing a peptide of formula (I): Sub-[L]-[NH-A-C(O)]n+m—OH (I) comprising: (a) reacting an immobilized compound of formula (II): Sub-(L)-[NH-A-C(O)]n—OH (II) with an amino acid ester or peptide derivative of formula (III): H—[NH-A-C(O)]m—O(tBu) (III) in the presence of a coupling agent to yield a peptide compound of general formula (IV): Sub-[L]-[NH-A-C(O)]n+m—O(tBu); (IV) (b) removing the tBu (t-butyl) group to produce a solid-support bound carboxylic acid or peptide derivative of general formula (I); wherein n is a positive integer, e.g., 1-10, preferably 1-5; m is a positive integer. |
| FILED | Thursday, May 23, 2002 |
| APPL NO | 10/156669 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/333 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214779 | Cox, III |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Bolder Biotechnology Inc. (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox, III (Louisville, Colorado) |
| ABSTRACT | The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed herein are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby. |
| FILED | Thursday, February 05, 2004 |
| APPL NO | 10/773654 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/399 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214790 | Russell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); Janssen Pharmaceutica N.V. (Beerse, Belgium) |
| INVENTOR(S) | Paul R. Russell (San Diego, California); Jorge E. Vialard (Beerse, Belgium); Michael N. Boddy (San Diego, California); Paul A. Shanahan (San Diego, California); Antonia Lopez-Girona (San Diego, California); Cecile-Marie D. D. Denis (Beerse, Belgium); Clare H. McGowan (Del Mar, California) |
| ABSTRACT | The present invention encompasses novel mammalian cell cycle checkpoint genes/DNA repair genes, cDNA or genomic DNA, isolated nucleic acids corresponding thereto, expression vectors comprising said nucleic acids, host cells transformed with said expression vectors, pharmaceutical compositions and the formulation of such compositions comprising said nucleic acids or proteins expressed therefrom, methods for treating a cell using such nucleic acids, proteins or pharmaceutical compositions, and the use of such nucleic acids or proteins in formulating a pharmaceutical preparation. |
| FILED | Tuesday, August 27, 2002 |
| APPL NO | 10/229355 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214813 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Xumu Zhang (State College, Pennsylvania); Wenjun Tang (State College, Pennsylvania) |
| ABSTRACT | Cyclic β-(acylamino)acrylate derivatives were hydrogenated using Ru-chiral phosphine ligand catalysts and thereafter converted to the corresponding cyclic β-aminoacids in high yield and enantioselectivity according to the reaction scheme: |
| FILED | Thursday, May 27, 2004 |
| APPL NO | 10/855103 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 560/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215122 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Invivo Corporation (Gainsville, Florida) |
| INVENTOR(S) | Qun Zhao (Gainesville, Florida); G. Randy Duensing (Gainesville, Florida); Hu Cheng (Gainesville, Florida); William A. Edelstein (Schenectady, New York) |
| ABSTRACT | The subject invention relates to a method and apparatus for producing stimulated MRI data. In an embodiment, a remote-controlled “smart phantom” can produce simulated data. The simulated data can be acquired from a MRI system. The subject device can generate control signals and send the generated control signals to secondary coils/probes placed in the subject smart phantom. The control signals determine the current flow in the secondary coils/probes, which act as local spin magnetization amplifiers and thus produce regions of variable contrast to noise ratio. The control signals can be generated with various parameters, such as BOLD models, different levels of contrast-to-noise ratio (CNR), signal intensities, and physiological signals. Comparisons can be made with the widely-used simulated data by computers. Validation of the subject smart phantom can be performed with both theoretical analysis and data of human subjects. |
| FILED | Monday, October 04, 2004 |
| APPL NO | 10/957822 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/318 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07213409 | Nuckols |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marshall L. Nuckols (Panama City, Florida) |
| ABSTRACT | A reconfigurable system is provided for effecting temperature changes. A first thermally-conductive container stores a metal hydride while a second thermally-conductive container stores a metal alloy that is capable of absorbing hydrogen atoms at a pressure that is less than the storage pressure of the metal hydride. A valved conduit links the metal hydride and the metal alloy. A thermal insulator is disposed about one of the containers depending on whether the system is to be used for cooling or heating. A circulating fluid is placed in thermal communication with the insulated container and with an environment requiring temperature changes. When the conduit's valve is opened, hydrogen atoms desorbed from the metal hydride are transported through the conduit and are absorbed by the metal alloy. Desorption of the hydrogen generates a cooling effect while absorption of the hydrogen generates heat. |
| FILED | Thursday, July 14, 2005 |
| APPL NO | 11/183309 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Refrigeration 062/408 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07213497 | Garcia et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Felipe Garcia (Panama City, Florida); Robert Woodall (Panama City Beach, Florida); Christopher Doyle (Panama City Beach, Florida); Greg Reitmeyer (Pamana City, Florida) |
| ABSTRACT | An inflatable trajectory altering and blast energy absorption system has a plenum with walls that are spaced apart from one another when the plenum is inflated. Flexible members, dispersed in the plenum and coupled thereto, are placed in tension when the plenum is inflated. Means for altering the trajectory of a projectile entering said plenum are dispersed within the plenum. |
| FILED | Monday, November 14, 2005 |
| APPL NO | 11/274708 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/36.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214000 | Marsh et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charles P. Marsh (Urbana, Illinois); Julie L. Webster (Peoria, Illinois); Gordon L. Cohen (Champaign, Illinois) |
| ABSTRACT | An unobtrusive on-grade barrier. One embodiment comprises a concrete-lined trench over which a biased hinged plate is affixed to an end wall of the trench. The biased hinge holds the free end of the plate against a tab affixed to the other end wall, assuring the plate does not rise above grade. The plate is supported for vehicle passage by a sliding mechanism energized by an actuator controlled by a controller that may be automated or operated by security personnel. The barrier may be configured so that vehicles may approach from either end. Upon authorizing access to the driver, the vehicle is permitted to pass over the supported plate. If the driver is not authorized access, the support is slid out of the way and any vehicle attempting to pass slides into the trench. Embodiments may include means for clearing the trench of a trapped vehicle. |
| FILED | Wednesday, November 03, 2004 |
| APPL NO | 10/979852 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Road structure, process, or apparatus 44/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214298 | Spence et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Charles F. Spence (Arcadia, California); Anne Y. Fu (Hacienda Heights, California); Stephen R. Quake (San Marino, California); Frances H. Arnold (Pasadena, California) |
| ABSTRACT | The invention provides a microfabricated device for sorting cells based on a desired characteristic, for example, reporter-labeled cells can be sorted by the presence or level of reporter on the cells. The device includes a chip having a substrate into which is microfabricated at least one analysis unit. Each analysis unit includes a main channel, having a sample inlet channel, typically at one end, and a detection region along a portion of its length. Adjacent and downstream from the detection region, the main channel has a discrimination region or branch point leading to at least two branch channels. The analysis unit may further include additional inlet channels, detection points, branch points, and branch channels as desired. A stream containing cells is passed through the detection region, such that on average one cell occupies the detection region at a given time. The cells can be sorted into an appropriate branch channel based on the presence or amount of a detectable signal such as an optical signal, with or without stimulation, such as exposure to light in order to promote fluorescence. |
| FILED | Monday, August 13, 2001 |
| APPL NO | 09/928590 |
| ART UNIT | 1753 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07214306 — Elevated potential deposition of rhenium on graphite substrates from a ReO2/H2O2 solution
| US 07214306 | Ferrando |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William A. Ferrando (Arlington, Virginia) |
| ABSTRACT | A method of depositing rhenium onto a substrate comprising dissolving rhenium oxide in a hydrogen peroxide solution, immersing a negative and a positive electrode into the solution, immersing a substrate to be coated with rhenium into the solution next to the negative electrode or, alternatively, using the substrate to be coated as the negative electrode, and applying a current between the two electrodes. |
| FILED | Monday, April 18, 2005 |
| APPL NO | 11/108406 |
| ART UNIT | 1753 — Printing/Measuring and Testing |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214346 | Harper et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James Douglas Harper (Boston, Massachusetts); Richard Hart Mathews (Chelmsford, Massachusetts); Bernadette Johnson (Hollis, New Hampshire); Martha Susan Petrovick (Barre, Massachusetts); Ann Rundell (West Lafayette, Indiana); Frances Ellen Nargi (Concord, Massachusetts); Timothy Stephens (Lexington, Massachusetts); Linda Marie Mendenhall (Acton, Massachusetts); Mark Alexander Hollis (Concord, Massachusetts); Albert M. Young (Fishkill, New York); Todd H. Rider (Littleton, Massachusetts); Eric David Schwoebel (Belmont, Massachusetts); Trina Rae Vian (Groton, Massachusetts) |
| ABSTRACT | The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal. |
| FILED | Wednesday, February 06, 2002 |
| APPL NO | 10/467242 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214428 | Naasani |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Invitrogen Corporation (Carlsbad, California) |
| INVENTOR(S) | Imad Naasani (Columbus, Ohio) |
| ABSTRACT | The present invention provides for detection apparatus with functionalized fluorescent nanocrystal compositions and methods for making and using these compositions in biological detection applications, material separations, and in the production of biosensors. The compositions are fluorescent nanocrystals coated with at least one coating material comprising ligands with functional groups or moieties with conjugated electrons and moieties for imparting solubility to fluorescent nanocrystals in aqueous solutions. The coating material provides for functionalized fluorescent nanocrystal compositions which are water soluble, chemically stable, and emit light with a high quantum yield and/or luminescence efficiency when excited with light. The coating material may also have chemical compounds or ligands with moieties for bonding to target molecules and cells as well as moieties for cross-linking the coating. |
| FILED | Wednesday, April 09, 2003 |
| APPL NO | 10/410108 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214432 | Merfeld et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Glen David Merfeld (Loudonville, New York); Rainer Koeniger (Clifton Park, New York); Ali Ersin Acar (Clifton Park, New York); Paul Dean Sybert (Evansville, Indiana); Zhaohui Su (Jilin, China PRC) |
| ABSTRACT | A coating composition comprising components A, B and optionally C, wherein component A comprises at least one hydroxy-terminated polyarylate. Component B is an organic species which can react with the hydroxy terminal groups of component A, and component C is a catalyst or mixture of catalysts. The hydroxy-terminated polyarylates are prepared by a solution polymerization method. |
| FILED | Tuesday, September 30, 2003 |
| APPL NO | 10/676892 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/412 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214489 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (Santa Barbara, California) |
| ABSTRACT | Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PNA complementary to the target polynucleotide. The sensor PNA comprises a signaling chromophore to absorb energy from the excited multichromophore and emit light in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided. |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600286 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214498 | Nelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Benaroya Research Institute at Virginia Mason (Seattle, Washington) |
| INVENTOR(S) | Brad H. Nelson (Seattle, Washington); Bradley C. Stone (Seattle, Washington) |
| ABSTRACT | The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease. |
| FILED | Monday, March 25, 2002 |
| APPL NO | 10/106559 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214519 | Martin et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Emil Martin (Houston, Texas); Ferid Murad (Houston, Texas) |
| ABSTRACT | A method of screening a substance of interest for heme independent modulation of enzymatic activity of soluble guanylyl cyclase (sGC) is disclosed, comprising (a) obtaining αβCys105 mutant sGC enzyme; (b) determining activity of the mutant enzyme for forming cGMP from GTP in the presence of the substance of interest in a reaction medium; (c) determining activity as in step (b), except in the absence of the substance of interest; optionally, (d) including an activator other than the substance of interest in steps b) and c); e) comparing results of (b)–(d) to yield a comparison result; and f) from that value of that result, assessing activity of the substance of interest for modulating cGMP production by the mutant enzyme. Increased or decreased formation of cGMP in the presence of the substance of interest indicates activity of the substance for modulating heme independent cGMP production. |
| FILED | Wednesday, February 11, 2004 |
| APPL NO | 10/777008 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214543 | Schanze et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Kirk S. Schanze (Gainesville, Florida); James M. Boncella (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to a method and apparatus for sensing nitroaromatics. The subject invention can utilize luminescent, for example fluorescent and/or electroluminescent, aryl substituted polyacetylenes and/or other substituted polyacetylenes which are luminescent for sensing nitroaromatics. In a specific embodiment, the subject invention can utilize thin films of fluorescent and/or electroluminescent aryl substituted polyacetylenes and/or other substituted polyacetylenes which are fluorescent and/or electroluminescent. In a specific embodiment, the fluorescence from thin films of fluorescent, substituted polyacetylene, such as—poly-[1-phenyl-2-(4-trimethylsilylphenyl)ethyne] (PTMSDPA) is strongly quenched by the vapors of a variety of nitroaromatic compounds present at levels ranging from parts-per-million to parts-per-billion in air. |
| FILED | Tuesday, October 15, 2002 |
| APPL NO | 10/271671 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214787 | Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Leonard A. Smith (Clarksburg, Maryland); Michael P. Byrne (New Market, Maryland); John L. Middlebrook (Middletown, Maryland); Hugh Lapenotiere (Charlestown, West Virginia); Michael A. Clayton (Mt. Airy, Maryland); Douglas R. Brown (Gaithersburg, Maryland) |
| ABSTRACT | This invention is directed to preparation and expression of synthetic genes encoding polypeptides containing protective epitopes of botulinum neurotoxin (BoNT). The invention is also directed to production of immunogenic peptides encoded by the synthetic genes, as weel as recovery and purification of the immunogenic peptides from recombinant organisms. The invention is also directed to methods of vaccination against botulism using the expressed peptides. |
| FILED | Thursday, July 06, 2000 |
| APPL NO | 09/611419 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215045 | Myrick |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeybee Robotics, Ltd. (New York, New York) |
| INVENTOR(S) | Thomas M. Myrick (Warren, New Jersey) |
| ABSTRACT | A roll-ring conductive wheel is used to conduct electricity between the inner and outer races of rotating or moving parts. The conductive wheel is a thin-walled metal cylinder with a plurality of spokes connecting the outer cylindrical wall to a central hub. The preferred spokes are arcuate and the wheel is made flexible so that it can be compressed to an elliptical shape between the inner and outer conductive races for good electrical contact and to absorb slight deflections or gap variations between the races. The conductive wheel can have other shapes depending on the configuration of moving parts, such as a truncated cone shape for conical or wedge-shaped races. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/966362 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical transmission or interconnection systems 37/147 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215142 | Fairbanks |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Scott Fairbanks (Mountain View, California) |
| ABSTRACT | An inverse toggle circuit includes a pair of input connections for receiving each of four possible input signal combinations in a sequential rotational manner. Each of four data paths are defined to be exercised in accordance with a respective input signal combination. A first output connection is controlled by first and third data paths. A second output connection is controlled by second and fourth data paths. Each data path is defined such that a currently exercised data path generates an output signal having an asserted state on the output connection that is controlled by the currently exercised data path. The currently exercised data path is also defined to cause a next data path in the sequence to generate an output signal having a non-asserted state on the output connection that is controlled by the next data path. |
| FILED | Tuesday, December 13, 2005 |
| APPL NO | 11/304002 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Electronic digital logic circuitry 326/55 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215213 | Mescher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Charles Stark Draper Laboratory, Inc., The (Cambridge, Massachusetts) |
| INVENTOR(S) | Mark J. Mescher (West Newton, Massachusetts); Mathew Varghese (Arlington, Massachusetts); Marc Steven Weinberg (Needham, Massachusetts); Thomas Marinis (Haverhill, Massachusetts); Joseph W. Soucy (Winchester, Massachusetts) |
| ABSTRACT | A suspension of a chip-scale device is accomplished using a suspension frame and at least one first tether. The chip-scale suspension frame defines a first plane and an opening through the suspension frame. At least one first tether crosses the opening at a first angle relative to the first plane and can be used to position the chip-scale device at least partially within the opening. |
| FILED | Wednesday, July 13, 2005 |
| APPL NO | 11/181035 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Oscillators 331/94.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215221 | Ellis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Grant Andrew Ellis (Los Angeles, California); Jeong-Sun Moon (Moorpark, California); Ara K. Kurdoghlian (La Crescenta, California) |
| ABSTRACT | A compact amplifier output bias circuit is used as a broadband harmonic termination. The bias circuit is adapted as a harmonic termination circuit to produce an effective low impedance or act as a load at the signal harmonic frequencies while having the capability of supplying DC power to the amplifier stage, optionally, if needed. A pi network is coupled to an active device output and provides a low impedance at frequency bands above a frequency band of operation while allowing DC bias to be appliable to the active device output. |
| FILED | Monday, August 30, 2004 |
| APPL NO | 10/929619 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/125 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215252 | Schenck |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| INVENTOR(S) | Robert A. Schenck (Hebron, Connecticut) |
| ABSTRACT | A proximity sensor includes an antenna having a resonant frequency selected to correspond to a resonant frequency associated with a selected dimension of an item of interest. In one example, the antenna is selected to have a resonant frequency corresponding to a resonant frequency associated with the width of a turbine blade. The amount of electromagnetic coupling between the item of interest and the antenna provides an indication of the proximity or distance between them. Several embodiments for incorporating such a structure into a gas turbine air seal are disclosed. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/869170 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/686.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215545 | Moghaddam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saeed Moghaddam (Columbia, Maryland); John Lawler (N. Potomac, Maryland); Michael Ohadi (Clarksville, Maryland) |
| ABSTRACT | A liquid cooled heat sink for cooling integrated and power modules. The heat sink is formed of a Diamond, Silicon Carbide composite and is provided with heat transfer facilitating fins and an enclosure for routing the cooling liquid into heat transfer contact with the heat sink and its fins. |
| FILED | Tuesday, April 27, 2004 |
| APPL NO | 10/832895 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/699 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215826 | Nevis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew J. Nevis (Panama City, Florida); James F. Bryan (Lynn Haven, Florida); Brett W. Cordes (Panama City Beach, Florida); James S. Taylor (Panama City Beach, Florida); Mary C. Hulgan (Lynn Haven, Florida) |
| ABSTRACT | A rendering method converts three-dimensional streak tube imaging lidar (STIL) data to two-dimensional contrast and range maps thereof. A temporal portion of the STIL data is processed for each pixel of the three-dimensional image. Each temporal portion includes a Gaussian-like portion and non-Gaussian-like portions. Processing for each pixel includes: (i) removing noise from the temporal portion using the non-Gaussian-like portions wherein a filtered form of the Gaussian-like portion is formed, (ii) determining a non-integer center of mass of the filtered form of the Gaussian-like portion with the non-integer center of mass being indicative of a range value, and (iii) applying a mathematical interpolation function to determine amplitude of the filtered form of the Gaussian-like portion at the range value defined by the non-integer center of mass. The amplitude so-determined is indicative of a contrast value. The process is repeated for all pixels to thereby produce range and contrast maps. |
| FILED | Monday, April 28, 2003 |
| APPL NO | 10/429330 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/275 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215864 | Qian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | All Optronics, Inc. (, None) |
| INVENTOR(S) | Charles Qian (Gilbert, Arizona); Katherine X. Liu (Tucson, Arizona) |
| ABSTRACT | A method and a system for cleaning fiber-optic connectors utilizing compressed-gas cans are disclosed. In one preferred embodiment, a solvent delivery sub-system (200) consisting of a fiber-optic connector interfacing unit (250) and a solvent spraying device (260) is reviewed. In another preferred embodiment, a solvent/contaminant removal sub-system (300) comprising of a compressed-gas can (340), a pressure regulator (345), a particle filter (347), a heating element (349), and a fiber-optic connector interfacing unit (310) is detailed. An additional preferred embodiment (400) is disclosed wherein the solvent delivery and removal sub-systems being integrated. For both the solvent delivery and the solvent/contaminant removal sub-systems, the compressed-gas cans may be obtained commercially. The improved art disclosed herein offers an effective and low cost solution to cleaning fiber-optic connectors. |
| FILED | Monday, July 24, 2006 |
| APPL NO | 11/492362 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07216214 | Dally et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Massachusetts Institute of Technology (Cambridge, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Pala Alto, California) |
| INVENTOR(S) | William J. Dally (Stanford, California); Scott W. Rixner (Mountain View, California) |
| ABSTRACT | A memory processing approach involves implementation of memory status-driven access. According to an example embodiment, addresses received at an address buffer are processed for access to a memory relative to an active location in the memory. Addresses corresponding to an active location in the memory array are processed prior to addresses that do not correspond to an active location. Data is read from the memory to a read buffer and ordered in a manner commensurate with the order of received addresses at the address buffer (e.g., thus facilitating access to the memory in an order different from that received at the address buffer while maintaining the order from the read buffer). |
| FILED | Monday, May 15, 2006 |
| APPL NO | 11/434392 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/217 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE39620 | Smith |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Patrick Lawrence Smith (Manhattan Beach, California) |
| ABSTRACT | A geolocation method is applied for accurate targeting of a target using an airborne beacon as a pseudo star generated by a high altitude vehicle, and using optical sensors by a low altitude vehicle for imaging the beacon and target for generating accurate relative GPS positioning of the target for improved the geolocation of the target preferably for precise delivery of a payload to the target. The method is applicable to military and civilian needs for accurate delivery of a payload to a target, such as for precise delivery of humanitarian aid or weapon munitions. |
| FILED | Friday, March 18, 2005 |
| APPL NO | 11/084867 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/213 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07213473 | Mosier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia National Laboratories (Livermore, California) |
| INVENTOR(S) | Bruce P. Mosier (San Francisco, California); Robert W. Crocker (Fremont, California); Kamlesh D. Patel (Dublin, California); Cindy K. Harnett (Livermore, California) |
| ABSTRACT | An apparatus that couples automated injection with flow feedback to provide nanoliter accuracy in controlling microliter volumes. The apparatus comprises generally a source of hydraulic fluid pressure, a fluid isolator joined to the outlet of the hydraulic pressure source and a flow sensor to provide pressure-driven analyte metering. For operation generally and particularly in microfluidic systems the hydraulic pressure source is typically an electrokinetic (EK) pump that incorporates gasless electrodes. The apparatus is capable of metering sub-microliter volumes at flowrates of 1–100 μL/min into microsystem load pressures of up to 1000–50 psi, respectively. Flowrates can be specified within 0.5 μL/min and volumes as small as 80 nL can be metered. |
| FILED | Wednesday, December 15, 2004 |
| APPL NO | 11/016310 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/861.520 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07213476 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Meng-Dawn Cheng (Oak Ridge, Tennessee); Da-Ren Chen (Creve Coeur, Missouri) |
| ABSTRACT | A multi-stage differential mobility analyzer (MDMA) for aerosol measurements includes a first electrode or grid including at least one inlet or injection slit for receiving an aerosol including charged particles for analysis. A second electrode or grid is spaced apart from the first electrode. The second electrode has at least one sampling outlet disposed at a plurality different distances along its length. A volume between the first and the second electrode or grid between the inlet or injection slit and a distal one of the plurality of sampling outlets forms a classifying region, the first and second electrodes for charging to suitable potentials to create an electric field within the classifying region. At least one inlet or injection slit in the second electrode receives a sheath gas flow into an upstream end of the classifying region, wherein each sampling outlet functions as an independent DMA stage and classifies different size ranges of charged particles based on electric mobility simultaneously. |
| FILED | Friday, September 30, 2005 |
| APPL NO | 11/240161 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/865.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214333 | Mukundan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Rangachary Mukundan (Santa Fe, New Mexico); Eric L. Brosha (Los Alamos, New Mexico); Fernando Garzon (Santa Fe, New Mexico) |
| ABSTRACT | A mixed potential electrochemical sensor for the detection of gases has a ceria-based electrolyte with a surface for exposing to the gases to be detected, and with a reference wire electrode and a sensing wire electrode extending through the surface and fixed within the electrolyte as the electrolyte is compressed and sintered. The electrochemical sensor is formed by placing a wire reference electrode and a wire sensing electrode in a die, where each electrode has a first compressed planar section and a second section depending from the first section with the second section of each electrode extending axially within the die. The die is filled with an oxide-electrolyte powder and the powder is pressed within the die with the wire electrodes. The wire-electrodes and the pressed oxide-electrolyte powder are sintered to form a ceramic electrolyte base with a reference wire electrode and a sensing wire electrode depending therefrom. |
| FILED | Friday, July 18, 2003 |
| APPL NO | 10/623416 |
| ART UNIT | 1753 — Printing/Measuring and Testing |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/118 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214442 | Ramsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | John C. Ramsey (Los Alamos, New Mexico); Mahlon S. Wilson (Los Alamos, New Mexico) |
| ABSTRACT | The present invention is a fuel cell stack including at least one direct methanol fuel cell. A cathode manifold is used to convey ambient air to each fuel cell, and an anode manifold is used to convey liquid methanol fuel to each fuel cell. Tie-bolt penetrations and tie-bolts are spaced evenly around the perimeter to hold the fuel cell stack together. Each fuel cell uses two graphite-based plates. One plate includes a cathode active area that is defined by serpentine channels connecting the inlet manifold with an integral flow restrictor to the outlet manifold. The other plate includes an anode active area defined by serpentine channels connecting the inlet and outlet of the anode manifold. Located between the two plates is the fuel cell active region. |
| FILED | Thursday, June 17, 2004 |
| APPL NO | 10/871295 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/39 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214485 | Belinsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lovelace Respiratory Research Institute (Albuquerque, New Mexico) |
| INVENTOR(S) | Steven A. Belinsky (Albuquerque, New Mexico); William A. Palmisano (Edgewood, New Mexico) |
| ABSTRACT | A molecular marker-based method for monitoring and detecting cancer in humans. Aberrant methylation of gene promoters is a marker for cancer risk in humans. A two-stage, or “nested” polymerase chain reaction method is disclosed for detecting methylated DNA sequences at sufficiently high levels of sensitivity to permit cancer screening in biological fluid samples, such as sputum, obtained non-invasively. The method is for detecting the aberrant methylation of the p16 gene, O 6-methylguanine-DNA methyltransferase gene, Death-associated protein kinase gene, RAS-associated family 1 gene, or other gene promoters. The method offers a potentially powerful approach to population-based screening for the detection of lung and other cancers. |
| FILED | Friday, August 24, 2001 |
| APPL NO | 10/344815 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214734 | Chaiko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | David J. Chaiko (Naperville, Illinois) |
| ABSTRACT | The present invention provides barrier films having reduced gas permeability for use in packaging and coating applications. The barrier films comprise an anisotropic liquid crystalline composite layer formed from phyllosilicate-polymer compositions. Phyllosilicate-polymer liquid crystalline compositions of the present invention can contain a high percentage of phyllosilicate while remaining transparent. Because of the ordering of the particles in the liquid crystalline composite, barrier films comprising liquid crystalline composites are particularly useful as barriers to gas transport. |
| FILED | Tuesday, June 08, 2004 |
| APPL NO | 10/863617 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 524/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP17710 | Abrahamson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York) |
| INVENTOR(S) | Lawrence P. Abrahamson (Marcellus, New York); Richard F. Kopp (Marietta, New York); Lawrence B. Smart (Geneva, New York); Timothy A. Volk (Syracuse, New York) |
| ABSTRACT | A distinct male cultivar of Salix purpurea named ‘Fish Creek’, characterized by rapid stem growth producing greater than 30% more woody biomass than either of its parents (‘94001’ and ‘94006’) and 20% more biomass than a current production cultivar (‘SV1’). ‘Fish Creek’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Fish Creek’ displays a low incidence of rust disease or damage by beetles or sawflies. |
| FILED | Thursday, October 06, 2005 |
| APPL NO | 11/244988 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07214599 | Kauzlarich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Evergreen Solar Inc. (Marlborough, Massachusetts) |
| INVENTOR(S) | Susan M. Kauzlarich (Davis, California); Richard K. Baldwin (San Diego, California) |
| ABSTRACT | Silicon nanocrystals with chemically accessible surfaces are produced in solution in high yield. Silicon tetrahalide such as silicon tetrachloride (SiCl4) can be reduced in organic solvents, such as 1,2-dimethoxyethane(glyme), with soluble reducing agents, such as sodium naphthalenide, to give halide-terminated (e.g., chloride-terminated) silicon nanocrystals, which can then be easily functionalized with alkyl lithium, Grignard or other reagents to give easily processed silicon nanocrystals with an air and moisture stable surface. The synthesis can be used to prepare alkyl-terminated nanocrystals at ambient temperature and pressure in high yield. The two-step process allows a wide range of surface functionality. |
| FILED | Friday, July 23, 2004 |
| APPL NO | 10/897476 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214749 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Texas A and M University Systems (College Station, Texas) |
| INVENTOR(S) | Stephen A. Miller (College Station, Texas); Levi J. Irwin (College Station, Texas) |
| ABSTRACT | The present invention is directed to a novel composition, and to a method of making the composition, the composition being useful in catalyst systems for the homopolymerization and/or copolymerization of olefins, wherein such catalyst systems display a higher level of activity and stereoselectivity than previously reported. The present invention is also directed to novel polymeric compositions made with such catalyst systems, such as a novel syndiotactic polypropylene that melts at temperatures higher than previously reported. |
| FILED | Thursday, July 07, 2005 |
| APPL NO | 11/176723 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 526/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215337 | Heer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Jeffrey M. Heer (Berkeley, California); Stuart K. Card (Los Altos, California) |
| ABSTRACT | Techniques for estimating user interest in graph structures are provided. A graph structure containing at least two nodes, a threshold disinterest value and at least one interesting node within the graph structure are determined. Each determined interesting node is added to a set of active nodes. Adjacent nodes connected to the set of active nodes and associated with Degree-Of-Interest values more interesting than the threshold disinterest value are in turn added to the set of active nodes until no additional adjacent connected nodes have a Degree-Of-Interest value more interesting than the threshold value. A new visualization of the graph structure is determined based on the nodes in the set of active nodes. The interesting nodes may be determined based on specific indications of interest in a node, such as a mouse selections, or may be based on the user's focus of attention within the graph based information structure. |
| FILED | Thursday, December 18, 2003 |
| APPL NO | 10/737849 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/440 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215629 | Eppler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
| INVENTOR(S) | Walter Richard Eppler (Cranberry Township, Pennsylvania) |
| ABSTRACT | A magnetic recording device is provided according to the present invention for magnetic recording on a recording medium. The magnetic recording device includes a planar waveguide having a propagation axis. The planar waveguide allows light received thereby to propagate along the propagation axis. The magnetic recording device further includes a magnetic pole having a yoke disposed adjacent the planar waveguide and a pole tip extending into the planar waveguide along the propagation axis. By extending the pole tip into, and incorporating it with, the planar waveguide, the light propagating through the planar waveguide and a magnetic flux flowing through the magnetic pole are co-locatable on a recording medium disposed adjacent the magnetic recording device. |
| FILED | Wednesday, February 26, 2003 |
| APPL NO | 10/374451 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Dynamic information storage or retrieval 369/112.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07213967 | Simunovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Josip Simunovic (Raleigh, North Carolina); Kenneth R. Swartzel (Raleigh, North Carolina); Eric Adles (Raleigh, North Carolina) |
| ABSTRACT | A method of generating a temperature measurement for a batch or a continuous stream of material. The method includes providing a particle having a signal that changes at a pre-determined temperature; inserting the particle into the batch or continuous stream; and detecting a signal change from the particle to thereby generate a temperature measurement for the batch or continuous stream. A suitable system for use in carrying out the method is also described. |
| FILED | Tuesday, December 13, 2005 |
| APPL NO | 11/301933 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/102 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214303 | Naughton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Michael J. Naughton (Norwood, Massachusetts) |
| ABSTRACT | The various embodiments discloses a cantilever probe comprising a first electrode and a second electrode engaged to a substrate and a branched cantilever wherein the cantilever comprises a nanostruture. Furthermore, the probe comprises a first arm of the cantilever engaged to the first electrode and a second arm of the cantilever engaged to the second electrode. Additionally, the cantilever probe comprises an electrical circuit coupled to the cantilever wherein the electrical circuit is capable of measuring a change in piezoresistance of the cantilever resulting from an atomic force and/or a magnetic force applied to the cantilever. Additionally, the invention discloses a method of performing atomic force microscopy, magnetic force microscopy, or magnetic resonance force microscopy. The nanostructures may comprise carbon or non-carbon materials. Additionally, the nanostructures may include nanotubes, nanowire, nanofibers and various other types of nanostructures. |
| FILED | Monday, May 02, 2005 |
| APPL NO | 11/119859 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214489 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (Santa Barbara, California) |
| ABSTRACT | Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PNA complementary to the target polynucleotide. The sensor PNA comprises a signaling chromophore to absorb energy from the excited multichromophore and emit light in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided. |
| FILED | Friday, June 20, 2003 |
| APPL NO | 10/600286 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07216123 | Kamvar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of the LeLand Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Sepandar D. Kamvar (Palo Alto, California); Taher H. Haveliwala (Mountain View, California); Glen Jeh (San Francisco, California); Gene Golub (Stanford, California) |
| ABSTRACT | Techniques for assigning ranks to nodes in a large linked database, such as world wide web or any other hypermedia database, partition the nodes so that the link matrix has a predominantly block-diagonal form. Within each block, a local rank is computed for nodes in the block, possibly by different computer in a distributed computing environment. A block rank is then estimated for each block as a whole, and may optionally include block-level weights to implement customized ranking. The local ranks and block ranks are then combined to form a global rank, which may be used to rank the nodes. Alternatively, a global rank vector for the database may be used as an initial vector in an iterative link-based ranking scheme to obtain more accurate global ranks for the nodes. The global rank vector may be divided to provide local rank vectors for use in subsequent applications of the method. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646331 |
| ART UNIT | 2162 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07214519 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Emil Martin (Houston, Texas); Ferid Murad (Houston, Texas) |
| ABSTRACT | A method of screening a substance of interest for heme independent modulation of enzymatic activity of soluble guanylyl cyclase (sGC) is disclosed, comprising (a) obtaining αβCys105 mutant sGC enzyme; (b) determining activity of the mutant enzyme for forming cGMP from GTP in the presence of the substance of interest in a reaction medium; (c) determining activity as in step (b), except in the absence of the substance of interest; optionally, (d) including an activator other than the substance of interest in steps b) and c); e) comparing results of (b)–(d) to yield a comparison result; and f) from that value of that result, assessing activity of the substance of interest for modulating cGMP production by the mutant enzyme. Increased or decreased formation of cGMP in the presence of the substance of interest indicates activity of the substance for modulating heme independent cGMP production. |
| FILED | Wednesday, February 11, 2004 |
| APPL NO | 10/777008 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214627 | Merrett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
| INVENTOR(S) | J. Neil Merrett (Starkville, Mississippi); Tamara Isaacs-Smith (Auburn, Alabama); David C. Sheridan (South Burlington, Vermont); John R. Williams (Opelika, Alabama) |
| ABSTRACT | A graded junction termination extension in a silicon carbide (SiC) semiconductor device and method of its fabrication using ion implementation techniques is provided for high power devices. The properties of silicon carbide (SiC) make this wide band gap semiconductor a promising material for high power devices. This potential is demonstrated in various devices such as p-n diodes, Schottky diodes, bipolar junction transistors, thyristors, etc. These devices require adequate and affordable termination techniques to reduce leakage current and increase breakdown voltage in order to maximize power handling capabilities. The graded junction termination extension disclosed is effective, self-aligned, and simplifies the implementation process. |
| FILED | Tuesday, August 09, 2005 |
| APPL NO | 11/201066 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/745 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07216036 | Brady et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Tye M. Brady (Southborough, Massachusetts); Anthony S. Kourepenis (Acton, Massachusetts); William F. Wyman, Jr. (North Falmouth, Massachusetts) |
| ABSTRACT | An integrated inertial stellar attitude sensor for an aerospace vehicle includes a star camera system, a gyroscope system, a controller system for synchronously integrating an output of said star camera system and an output of said gyroscope system into a stream of data, and a flight computer responsive to said stream of data for determining from the star camera system output and the gyroscope system output the attitude of the aerospace vehicle. |
| FILED | Wednesday, July 16, 2003 |
| APPL NO | 10/621097 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/213 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 07214492 | Rublee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Greensboro (Greensboro, North Carolina) |
| INVENTOR(S) | Parke A. Rublee (Greensboro, North Carolina); Vincent C. Henrich, III (Greensboro, North Carolina) |
| ABSTRACT | Disclosed are arrays for monitoring ecosystems, such as bodies of water, and methods and systems for making such arrays. In one embodiment, the array may include a plurality of oligonucleotides immobilized at known locations on a substrate, such that each location on the array is an oligonucleotide having a sequence derived from a single, predetermined operational taxonomic unit (OTU). The sequences immobilized on the array may be from known, or unknown organisms. Also disclosed are methods for identifying and isolating bioindicators diagnostic of specific ecosystems. The arrays and bioindicators of the invention may be used for rapid, and continual monitoring of ecosystems. |
| FILED | Thursday, March 03, 2005 |
| APPL NO | 11/071849 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07214531 | Ladjevardi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Disan, Inc. (San Diego, California) |
| INVENTOR(S) | Mahmoud Ladjevardi (La Jolla, California); Theodore Sand (Poway, California) |
| ABSTRACT | An assay system has a chamber that receives a test strip onto which a sample comprising an analyte has been placed. The chamber is in gaseous communication with a piezoelectric material that generates an electrical signal in response to a pressure change in the chamber that is caused by a reaction between the analyte and a reagent. |
| FILED | Monday, April 15, 2002 |
| APPL NO | 10/479782 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07214524 | Reddy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as reprsented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Sanjay M. Reddy (College Station, Texas); Blanca M. Lupiani (College Station, Texas) |
| ABSTRACT | An effective vaccine for Marek's disease may be prepared using a viral agent which is a Marek's disease virus unable to express a functional meq protein. This viral agent is effective to elicit an immune response in a chicken to very virulent strains of Marek's disease virus without causing a significant degree of pathogenicity in the inoculated bird. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent with a pharmaceutically acceptable carrier or diluent. |
| FILED | Tuesday, May 06, 2003 |
| APPL NO | 10/430773 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 07214346 | Harper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James Douglas Harper (Boston, Massachusetts); Richard Hart Mathews (Chelmsford, Massachusetts); Bernadette Johnson (Hollis, New Hampshire); Martha Susan Petrovick (Barre, Massachusetts); Ann Rundell (West Lafayette, Indiana); Frances Ellen Nargi (Concord, Massachusetts); Timothy Stephens (Lexington, Massachusetts); Linda Marie Mendenhall (Acton, Massachusetts); Mark Alexander Hollis (Concord, Massachusetts); Albert M. Young (Fishkill, New York); Todd H. Rider (Littleton, Massachusetts); Eric David Schwoebel (Belmont, Massachusetts); Trina Rae Vian (Groton, Massachusetts) |
| ABSTRACT | The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal. |
| FILED | Wednesday, February 06, 2002 |
| APPL NO | 10/467242 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07214749 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Texas A and M University Systems (College Station, Texas) |
| INVENTOR(S) | Stephen A. Miller (College Station, Texas); Levi J. Irwin (College Station, Texas) |
| ABSTRACT | The present invention is directed to a novel composition, and to a method of making the composition, the composition being useful in catalyst systems for the homopolymerization and/or copolymerization of olefins, wherein such catalyst systems display a higher level of activity and stereoselectivity than previously reported. The present invention is also directed to novel polymeric compositions made with such catalyst systems, such as a novel syndiotactic polypropylene that melts at temperatures higher than previously reported. |
| FILED | Thursday, July 07, 2005 |
| APPL NO | 11/176723 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 526/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07215298 | Fraschilla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | John Fraschilla (Hainesport, New Jersey); Robert M. Reese (Mt. Laurel, New Jersey) |
| ABSTRACT | An antenna array coacts with a ground plane for radiation. Calibration of the array is accomplished with the aid of one or more extensible calibration antenna elements, such as monopole antenna elements. Each calibration monopole is ordinarily retracted below the ground plane and is not “energized.” When calibration is desired, it is extended to protrude above the ground plane so as to achieve mutual coupling with one or more of the elements of the array antenna. Calibration signals may be passed in either direction. The calibration antenna may be extended/retracted by vacuum, mechanical device, or electrical motor. |
| FILED | Tuesday, September 06, 2005 |
| APPL NO | 11/219978 |
| ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/853 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07215860 | Engelberth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Jon W. Engelberth (Denville, New Jersey); Douglas P. Holcomb (Morris Plains, New Jersey); Paul F. Wysocki (Flemington, New Jersey) |
| ABSTRACT | The present invention provides an apparatus comprising a passive optical transmission fiber. The passive optical transmission fiber comprises a passive glass fiber core, a glass optical inner cladding surrounding the core and a glass optical outer cladding surrounding the inner cladding. The inner cladding has a lower index of refraction than the passive glass fiber core and the outer cladding has a lower index of refraction than the inner cladding. The passive optical transmission fiber also comprises a second optical segment coupled to the optical fiber. The second optical segment is configured to dissipate light in the inner cladding. |
| FILED | Monday, May 02, 2005 |
| APPL NO | 11/120212 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 08, 2007.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2007/fedinvent-patents-20070508.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page