FedInvent™ Patents
Patent Details for Tuesday, July 31, 2007
This page was updated on Sunday, March 26, 2023 at 08:43 PM GMT
Department of Defense (DOD)
US 07249463 | Anderson et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | William C. Anderson (Springdale, Ohio); Jesse Senyo (Williamstown, Kentucky); Michael J. Epstein (Mason, Ohio); Zhifeng Dong (Cincinnati, Ohio) |
ABSTRACT | A fastener shield for use in a fluid flow path within a gas turbine engine for reducing fluid drag and heating generated by fluid flow over a plurality of circumferentially spaced fasteners. The fastener shield has a radially-extending, downstream-facing mounting flange with a plurality of circumferentially spaced bolt holes positioned to receive respective engine mounting bolts therethrough and to attach the mounting flange to elements of the turbine engine. A curved, upstream-facing fastener shield cover is positioned in spaced-apart relation to the mounting flange for at least partially covering and separating an exposed, upstream-facing portion of the bolts from the fluid flow to thereby reduce drag and consequent heating of the bolts. |
FILED | Wednesday, September 15, 2004 |
APPL NO | 10/941213 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Power plants 060/798 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249567 | Wallin |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | C. Roger Wallin (Portsmouth, Rhode Island) |
ABSTRACT | Disclosed is a launch system of an affixed lower section of launch tubing and an upper section of launch tubing configured to telescope vertically from a stowed position within the hull of a submarine to a position just above the ocean surface for a launch operation of a projectile, with the upper section returning to a stowed position after the launch operation. The launch system is capable of launching a projectile to engage air contacts by the discharge of high pressure fluid air, through the length of the upper and lower sections to impact the projectile for launch. The launch system includes surveillance, command and control elements as well as operational connection to additional projectile stowage and a supply of high pressure fluid. The projectile in use with the launch system can support surveillance and communications operations. |
FILED | Monday, December 20, 2004 |
APPL NO | 11/015804 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ships 114/319 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249640 | Horchler et al. |
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INVENTOR(S) | Andrew D. Horchler (Cleveland, Ohio); Roger D. Quinn (Akron, Ohio); Bram Lambrecht (Cleveland Heights, Ohio); Jeremy M. Morrey (Denver, Colorado) |
ABSTRACT | The present invention relates to novel, highly mobile small robots called “Mini-WHEGS™” that can run and jump. They are derived from our larger WHEGS™(“wheel-like lecis”) series of robots, which benefit from abstracted cockroach locomotion principles. Part of their success is derived from the three spoked appendages, called “WHEGS™”, which combine the speed and simplicity of wheels with the climbing mobility of legs. To be more compact than the larger WHEGS™ vehicles, Mini-WHEGS™ uses four wheel-like legs in an alternating diagonal gait. These 9 cm long robots can run at sustained speeds of over 10 body lengths per second and climb obstacles that are taller than their leg length. They can run forward and backward, on either side. Their robust construction allows them to tumble down a flight of stairs with no damage and carry a payload equal to twice their weight. A jumping mechanism enables Mini-WHEGS™ to surmount much larger obstacles such as stair steps. |
FILED | Thursday, May 13, 2004 |
APPL NO | 10/845583 |
ART UNIT | 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Motor vehicles 180/8.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249711 | Steinbrecher |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Donald H. Steinbrecher (Brookline, Massachusetts) |
ABSTRACT | A plurality of remotely readable sensor apparatus and reader systems for collecting data frames from all apparatus within the reader field of view. Each sensor apparatus converts one or more environmental observable into information signals, converts the information signals into digital data and appends other discriminating digital data as desired to form a digital data frame. The state of a diode, connected to an antenna with the digital data frame, is modulated and a timing apparatus controls the digital-data-frame start times. The modulated states of the diode connected to a sensor-apparatus antenna are chosen so the angle of the antenna reflection coefficient is modulated between two values separated by approximately 180 degrees, so a carrier signal received by the antenna effects a bi-phase modulated signal containing the digital data frame that is reflected by the sensor-apparatus antenna toward the reader receiver antenna. |
FILED | Friday, February 25, 2005 |
APPL NO | 11/061164 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Registers 235/451 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249723 | He et al. |
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ASSIGNEE(S) | NGX, Inc. (Phoenixville, Pennsylvania) |
INVENTOR(S) | Jianhong He (Irwin, Pennsylvania); Qiping Zhong (Cupertino, California); Srikanth Raghunathan (Irwin, Pennsylvania) |
ABSTRACT | The invention provides high surface area talc compositions by a novel hybrid milling method or soaking method. The hybrid milling method comprises dry milling talc powder followed by mixing with water and wet milling to provide a nano-talc slurry with high surface area, also of the invention. The soaking method comprises dry milling talc powder followed by mixing with water and soaking to provide high surface area nano-talc slurry. The slurry may be dewatered and dried to provide dry nano-talc powder. The nano-talc powder provided by the invention is a novel hydrophilic talc composition. Further embodiments of the invention include organic solvent dispersed nano-talc slurries and methods for providing the same. These slurries can be used to provide polymer nano-talc composites in the form of coatings, sealing and gasketing materials, foams, extruded thermoplastic and thermoset sheets and films, thermoplastic pellets, thermoplastic and thermoset molded polymer composite articles. Another embodiment is a polyurethane nano-talc composite article derived from the organic solvent dispersed slurries. |
FILED | Tuesday, December 21, 2004 |
APPL NO | 11/018946 |
ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Solid material comminution or disintegration 241/21 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249730 | Flippen, Jr. |
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ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Luther D. Flippen, Jr. (Waldorf, Maryland) |
ABSTRACT | Disclosed are a system, method, and program storage device implementing the method, of data fusion, wherein the method comprises determining pre-launch data affecting a flight of a self-sensing air-bursting ballistic projectile, the projectile comprising a plurality of independent data sensors; predicting a trajectory path of the projectile based on a target location of the projectile; calculating trajectory path errors based on the predicted trajectory path; generating in-flight data from each of the data sensors; combining the in-flight data into a single time-series output using a fusion filter; tracking a trajectory position of the projectile based on the single time-series output, pre-launch data, and the trajectory path errors; comparing the tracked trajectory path with the predicted trajectory path; analyzing the in-flight data to gauge successful navigation of the projectile to the target location; and self-guiding the projectile to the target location based on the trajectory position. |
FILED | Thursday, September 23, 2004 |
APPL NO | 10/947128 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Aeronautics and astronautics 244/3.150 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249859 | Ptasinski et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Joanna Ptasinski (San Diego, California); Randy L. Shimabukuro (San Diego, California); Stephen D. Russell (San Diego, California) |
ABSTRACT | A sensing system comprises a corner-cube reflector that has three reflective surfaces wherein at least one of the reflective surfaces is a surface of a bimaterial cantilever. The reflective surface of the bimaterial cantilever undergoes a change between a substantially planar shape and a curved shape upon direct exposure to an agent of interest. Such a change is perceived by a suitable detector. |
FILED | Thursday, December 18, 2003 |
APPL NO | 10/750626 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/529 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249881 | Pipe et al. |
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ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Kevin P. Pipe (Coldwater, Michigan); Rajeev J. Ram (Boston, Massachusetts) |
ABSTRACT | A method and apparatus for performing characterization of devices is presented. The characteristic of the device are determined by obtaining a first temperature measurement in a first location of a device, obtaining a second temperature measurement, computing the difference between the temperature measurements and, using the temperatures and/or the temperature difference, a characteristic of the device is determined. |
FILED | Friday, April 29, 2005 |
APPL NO | 11/119093 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Thermal measuring and testing 374/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249964 | Hoffman et al. |
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ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Edward K. Hoffman (Anaheim, California); Brian J. Hupf (Garden Grove, California) |
ABSTRACT | A device for providing strain relief between an electrical connector and a wiring harness having wires or cables already joined to the contacts of the connector includes a T-shaped plate having axial and transverse members and a pair of opposing, inwardly facing, U-shaped structures disposed at opposite ends of the transverse member and extending at a right angle to the plate from a front edge thereof. The device is mounted on the connector with the U-shaped structures respectively straddling a corresponding mounting flange of the connector and a distal end portion of the axial member extending rearward over a portion of the harness extending rearward from the connector. The two rearward extending portions of the plate and harness are cinched together with a strap or the like. The device can be installed after the harness has been assembled without the need to remove the wires or contacts from the connector. |
FILED | Tuesday, January 31, 2006 |
APPL NO | 11/343577 |
ART UNIT | 2839 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Electrical connectors 439/471 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250134 | Kernan et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Brian D. Kernan (Arlington, Massachusetts); Emanuel M. Sachs (Newton, Massachusetts); Samuel M. Allen (Jamaica Plain, Massachusetts); Adam M. Lorenz (Somerville, Massachusetts) |
ABSTRACT | A steel powder metal skeleton is infiltrated with an infiltrant composition similar to the skeleton, with an additional agent that depresses the melting point of the infiltrant relative to the skeleton. Infiltration is driven primarily by capillary pressure. The powder and infiltrant compositions differ primarily only in a higher concentration of a melting point depressant agent “MPD” in the infiltrant. Carbon (C) and silicon (Si) and several other elements can be elements in an MPD, either alone or in combination. Certain steel target compositions are such that a complementary infiltrant, and skeleton can be chosen such that a skeleton will remain solid at an infiltration temperature at which the infiltrant can be melted and fully infiltrated, and further where there is a persistent two phase field, with a liquid phase that is large enough (greater than 7% vol, and typically between 20 and 40 vol %) so that flow can be maintained without choke off from diffusional solidification. The solid and the liquid phases remaining after any diffusional solidification have different compositions, with a bulk composition of the target. Typically the difference is slight, and the full part is substantially homogeneous. Heat treating, such as austenitizing, quenching, or slow cooling and tempering, can improve homogeneity and mechanical properties. The MPD can have a relatively high diffusivity and solubility in the skeleton. Methods of designing systems of target, skeleton and infiltrant compositions and infiltration temperature are disclosed. |
FILED | Wednesday, November 26, 2003 |
APPL NO | 10/723989 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Powder metallurgy processes 419/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250138 | Wick |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as respresented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Charles Harold Wick (Darlington, Maryland) |
ABSTRACT | A system and method for detecting the presence of submicron sized particles in a sample taken from the environment includes a collecting a sample from the environment and purifying and concentrating the submicron particles in a sample based on the size of the particles. The purified and concentrated particles are detected with an apparatus which includes an electrospray assembly having an electrospray capillary, a differential mobility analyzer which receives the output from the capillary, and a condensation particle device for counting the number of particles that pass through the differential mobility analyzer. The system is intended to collect a sample containing submicron size particles having a size range of from greater than 350 nanometers to about 1000 nanometers and wherein the particles include viruses, prions, viral subunits, viral cores of delipidated viruses, plant viruses, standard particles used for calibrating equipment, coated particles, spherical particles, metallic-core shelled particles, polymers, fluorescent microspheres, powders, nanoclusters, particles produced as a result of manufacturing processes, and portions of bacteria. |
FILED | Monday, December 09, 2002 |
APPL NO | 10/314328 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250147 | Tour et al. |
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INVENTOR(S) | James M. Tour (Bellaire, Texas); Jeffrey L. Bahr (Houston, Texas); Jiping Yang (San Jose, California) |
ABSTRACT | The invention incorporates new processes for the chemical modification of carbon nanotubes. Such processes involve the derivatization of multi- and single-wall carbon nanotubes, including small diameter (ca. 0.7 nm) single-wall carbon nanotubes, with diazonium species. The method allows the chemical attachment of a variety of organic compounds to the side and ends of carbon nanotubes. These chemically modified nanotubes have applications in polymer composite materials, molecular electronic applications and sensor devices. The methods of derivatization include electrochemical induced reactions thermally induced reactions (via in-situ generation of diazonium compounds or pre-formed diazonium compounds), and photochemically induced reactions. The derivatization causes significant changes in the spectroscopic properties of the nanotubes. The estimated degree of functionality is ca. 1 out of every 20 to 30 carbons in a nanotube bearing a functionality moiety. Such electrochemical reduction processes can be adapted to apply site-selective chemical functionalization of nanotubes. Moreover, when modified with suitable chemical groups, the derivatized nanotubes are chemically compatible with a polymer matrix, allowing transfer of the properties of the nanotubes (such as, mechanical strength or electrical conductivity) to the properties of the composite material as a whole. Furthermore, when modified with suitable chemical groups, the groups can be polymerized to form a polymer that includes carbon nanotubes |
FILED | Tuesday, January 29, 2002 |
APPL NO | 10/470517 |
ART UNIT | 1754 — Printing/Measuring and Testing |
CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250225 | Hazel et al. |
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ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Brian Thomas Hazel (West Chester, Ohio); Ramgopal Darolia (West Chester, Ohio); Brett Allen Rohrer Boutwell (Liberty Township, Ohio); David John Wortman (Hamilton, Ohio) |
ABSTRACT | An intermetallic composition suitable for use as an environmentally-protective coating on surfaces of components used in hostile thermal environments, including the turbine, combustor and augmentor sections of a gas turbine engine. The coating contains the gamma-prime (Ni3Al) nickel aluminide intermetallic phase and either the beta (NiAl) nickel aluminide intermetallic phase or the gamma solid solution phase. The coating has an average aluminum content of 14 to 30 atomic percent and an average platinum-group metal content of at least 1 to less than 10 atomic percent, the balance of the coating being nickel, incidental impurities, and optionally hafnium. |
FILED | Monday, September 26, 2005 |
APPL NO | 11/162838 |
ART UNIT | 1775 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Stock material or miscellaneous articles 428/680 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250267 | Walt et al. |
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ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | David R. Walt (Lexington, Massachusetts); Caroline L. Schauer (Silver Spring, Maryland); Frank J. Steemers (San Diego, California) |
ABSTRACT | The present invention provides a novel cross-reactive sensor system utilizing cross-reactive recognition elements. In the inventive system, each of said one or more cross-reactive recognition elements is capable of interacting with more than one species of liquid analyte of interest, whereby each of said one or more cross-reactive recognition elements reacts in a different manner with each of said one or more species of liquid analytes of interest to produce a detectable agent of each analyte of interest, whereby said detectable agent is analyzed and the information is processed for data acquisition and interpretation. In certain preferred embodiments, the detectable agent and/or change is detected directly, while in certain other preferred embodiments, the detectable agent and/or change is detected with the help of a transducing agent capable of relaying information about each detectable agent generated for each of said species of liquid analyte of interest, whereby said information is processed for data acquisition and interpretation. The present invention also provides method for the analysis of analytes comprising contacting one or more analytes with the inventive system described above. |
FILED | Wednesday, March 14, 2001 |
APPL NO | 10/221815 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250360 | Shealy et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
INVENTOR(S) | James R. Shealy (Ithaca, New York); Joseph A. Smart (Mooresville, North Carolina) |
ABSTRACT | A single step process for nucleation and subsequent epitaxial growth on a lattice mismatched substrate is achieved by pre-treating the substrate surface with at least one group III reactant or at least one group II reactant prior to the introduction of a group V reactant or a group VI reactant. The group III reactant or the group II reactant is introduced into a growth chamber at an elevated growth temperature to wet a substrate surface prior to any actual crystal growth. Once the pre-treatment of the surface is complete, a group V reactant or a group VI reactant is introduced to the growth chamber to commence the deposition of a nucleation layer. A buffer layer is then grown on the nucleation layer providing a surface upon which the epitaxial layer is grown preferably without changing the temperature within the chamber. |
FILED | Wednesday, March 02, 2005 |
APPL NO | 11/069040 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/603 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250401 | Schloss |
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APPLICANT(S) | |
ASSIGNEE(S) | Advanced Therapeutics and Diagnostics, LC (Lawrence, Kansas) |
INVENTOR(S) | John V. Schloss (Valencia, California) |
ABSTRACT | A method is provided for the preparation of compounds of the formula (R1)(R2)NC(═X)S(O)nR3 or (R1)(R2)NC(═X)OS(O)nR3, wherein R1, R2 and R3, X and n have any of the meanings defined in the specification. A method is also provided for the detection and quantitation of compounds of the formula (R1)(R2)NC(═X)OS(O)nR3. A method to link a therapeutic agent to a compound that is conjugated to glutathione is also provided for the purpose of improving the therapeutic properties of the therapeutic agent. Novel compounds, intermediates, pharmaceutical compositions and methods of use are also provided. |
FILED | Friday, May 07, 2004 |
APPL NO | 10/841950 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250499 | Mirkin et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Nanosphere Inc. (Northbrook, Illinois) |
INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Robert L. Letsinger (Wilmette, Illinois); Zhi Li (Evanston, Illinois) |
ABSTRACT | The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids. |
FILED | Tuesday, November 18, 2003 |
APPL NO | 10/716829 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250523 | Odom et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Aaron L. Odom (Lansing, Michigan); James T. Ciszewski (East Lansing, Michigan) |
ABSTRACT | Compounds and processes for catalytic ring-opening cyclooligomerization metathesis and ring-closing metathesis of olefins are described. The compound is a molybdenum or tungsten metal (M) complex which comprises an imido ligand (N—R) bound to the M to provide an M=N—R site, an M=C reaction site wherein the C of the M=C reaction site is tethered to the R of the imido ligand via a carbon or carbon and heteroatom (NOS) chain containing 1 to 12 carbon atoms to form a ring structure, and two to four ligands (R′) bound to the M to provide two to four M-R′ sites. In particular embodiments, the M-R′ sites include each of the oxygens of a dialkoxide ligand or each of the nitrogens of an η1-pyrrolyl ligand bound to the M. |
FILED | Wednesday, October 22, 2003 |
APPL NO | 10/691328 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 556/32 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250568 | Dow et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Eric G. Dow (Barrington, Rhode Island); James D. Hrubes (Middletown, Rhode Island) |
ABSTRACT | An assembly for vehicle deceleration and buoyancy comprises a pair of doors enclosing flotation bags inflatable for buoyant recovery of the torpedo. In operation, the doors are controllably forced open to an initial angle off a longitudinal axis of the assembly to a fully-deployed position by hydrodynamic forces of the movement of the vehicle. From the doors blocking the hydrodynamic forces, the vehicle decelerates. The hydrodynamic braking action of the doors reduces the time required to reach terminal velocity, thus reducing the depth the vehicle sinks and enabling recovery with less gas required for inflation. |
FILED | Friday, June 30, 2006 |
APPL NO | 11/484147 |
ART UNIT | 3617 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Ships 114/20.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250624 | Freedman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Microsoft Corporation (Redmond, Washington) |
INVENTOR(S) | Michael H. Freedman (Redmond, Washington); Chetan V. Nayak (Santa Monica, California) |
ABSTRACT | A quantum computer can only function stably if it can execute gates with extreme accuracy. “Topological protection” is a road to such accuracies. Quasi-particle interferometry is a tool for constructing topologically protected gates. Assuming the corrections of the Moore-Read Model for v= 5/2's FQHE (Nucl. Phys. B 360, 362 (1991)) we show how to manipulate the collective state of two e/4-charge anti-dots in order to switch said collective state from one carrying trivial SU(2) charge, |1>, to one carrying a fermionic SU(2) charge |ε>. This is a NOT gate on the {|1>, |ε>} qubit and is effected by braiding of an electrically charged quasi particle σ which carries an additional SU(2)-charge. Read-out is accomplished by σ-particle interferometry. |
FILED | Friday, September 23, 2005 |
APPL NO | 11/233653 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250900 | Ohnishi |
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APPLICANT(S) | |
ASSIGNEE(S) | Information Systems Laboratories, Inc. (San Diego, California) |
INVENTOR(S) | Katsumi Ohnishi (Centreville, Virginia) |
ABSTRACT | A radar system and method for detecting targets using pulse-compressed signals is disclosed. In one application, the systems and methods can be used to detect one or more relatively small targets whose pulse-compressed signals are masked by the time-sidelobes of a larger target's return signal. The method includes an iterative, detect-and-subtract signal algorithm that processes the post-compressed signal to detect multiple targets. Specifically the processing algorithm operates on the post-compressed signal to identify a point spread function (PSF) that corresponds to the relatively large target. Once identified, the PSF corresponding to the largest target in the post-compressed signal is subtracted from the post-compressed signal to generate a residual signal. This residual signal, in turn, includes the PSFs for the other targets. This process of identifying and subtracting the PSF of the largest target in the residual signal is then repeated until all targets are detected. |
FILED | Friday, August 19, 2005 |
APPL NO | 11/207430 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/93 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250921 | Henry et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Willard I. Henry (San Diego, California); Thinh Q. Ho (Anaheim, California) |
ABSTRACT | A method and apparatus for a multiband frequency distributed circuit apparatus with FSS. The apparatus includes a circuit, a first dielectric layer, a first FSS layer, a second layer and a ground plane. The first dielectric layer is operatively coupled to the circuit. The first FSS layer is operatively coupled to the first dielectric layer and is capable of passing a first frequency band. The second layer is operatively coupled to the first FSS layer and includes a dielectric material. The ground plane is operatively coupled to the second layer. A method for implementing a multiband frequency distributed circuit is also disclosed. |
FILED | Thursday, December 18, 2003 |
APPL NO | 10/740297 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/909 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251195 | Reiff et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Christian G. Reiff (Arlington, Virginia); Harold Boesch, Jr. (Beltsville, Maryland); Bruce T. Benwell (Sumerduck, Virginia) |
ABSTRACT | An apparatus for generating an acoustic signal which has a dielectric substrate having opposed first and second sides. A pair of electrodes are mounted on the first surface of the substrate so that the electrodes are spaced apart from each other. A high voltage power source is electrically connected to the electrodes to produce a high voltage electric potential between the electrodes and this high voltage electric potential is less than a level sufficient to create a surface arc discharge along the first surface of the dielectric substrate. An electrical conductor strip is mounted to the second side of the substrate. A trigger signal circuit then applies a trigger voltage signal to either the electrical connector strip or one of the electrodes which varies the electric field between the electrodes in an amount sufficient to ionize air adjacent one of the electrodes and create a surface arc discharge along the first surface of the dielectric between the electrodes which generates the acoustic impulse as a byproduct of the discharge. |
FILED | Thursday, October 23, 2003 |
APPL NO | 10/693483 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/139 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251196 | Antonelli et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Lynn T. Antonelli (Cranston, Rhode Island); Fletcher A. Blackmon (Forestdale, Massachusetts) |
ABSTRACT | A passive acoustic sensor that may be employed to detect sounds emanating from under the surface of a body of water. The sensor uses optics to determine vibration on the surface of a water body to detect sound pressure waves from underwater sound sources. The sensor is deployed above the surface and has no direct interaction with anything under the surface that may be emanating sounds. This allows the invention to operate without interfering with potential sound sources as well as allows for numerous deployment methods. |
FILED | Tuesday, May 31, 2005 |
APPL NO | 11/151191 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/149 |
VIEW PATENT | @ USPTO: Full Text PDF |
07251563 — System and method for computing inorganic particle suspensions by wave and current action
US 07251563 | Keen |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Timothy R. Keen (Slidell, Louisiana) |
ABSTRACT | A method for estimating a suspended sediment distribution in an ocean region. The method includes receiving time-dependent variables including wave height, wave period, wave propagation direction, steady current magnitude, steady current direction, and water depth, and an estimate of bottom sediment distribution, calculating a new bottom sediment distribution using a sediment suspension and advection module, calculating a concentration of sediment by size at a plurality of depths using an ocean bottom boundary layer hydrodynamic module. A central module uses C++ language to transfer calculations from the sediment suspension and advection module and the ocean bottom boundary layer hydrodynamic module. |
FILED | Friday, September 16, 2005 |
APPL NO | 11/229430 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251564 | Posey et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Pamela Posey (Carriere, Mississippi); Ruth H Preller (Slidell, Louisiana); Gretchen Dawson (Slidell, Louisiana) |
ABSTRACT | A system and method for estimating ocean surface height and currents at points within a geographic grid. The method includes receiving bathymetric data from a global database, generating atmospheric forcing information based on a hurricane model, and estimating current and ocean height deviation for at least one grid point. In exemplary embodiments, the system is rapidly relocatable, has worldwide coverage, and can run on a PC at user selected frequencies and worldwide locations. |
FILED | Wednesday, November 02, 2005 |
APPL NO | 11/268397 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251605 | Belenger et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Robert V. Belenger (Raynham, Massachusetts); Gennaro R. Lopriore (Somerset, Massachusetts) |
ABSTRACT | A speech to touch translator assembly and method for converting spoken words directed to an operator into tactile sensations caused by combinations of pressure point exertions on the body of the operator, each combination of pressure points exerted signifying a phoneme of one of the spoken words, permitting comprehension of spoken words by persons that are deaf and blind. |
FILED | Monday, August 19, 2002 |
APPL NO | 10/224230 |
ART UNIT | 2626 — Selective Visual Display Systems |
CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/271 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251768 | Giannakis et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Georgios B. Giannakis (Minnetonka, Minnesota); Zhengdao Wang (Ames, Iowa); Shengli Zhou (Minneapolis, Minnesota) |
ABSTRACT | In general, joint error-control coding and linear precoding techniques are proposed for fading-resilient transmissions over frequency- at and frequency-selective fading channels encountered with high-rate wireless OFDM transmissions. For example, a wireless communication system includes a transmitter that applies non-linear codes and a linear precoder to a data stream to produce a joint coded-precoded waveform. A receiver receives the joint coded-precoded waveform from the transmitter via a wireless communication channel, and demodulates the joint-coded precoded waveform to produce estimated data. The combination offers a multiplicative benefit to the diversity achievable by the wireless communication system. |
FILED | Monday, April 21, 2003 |
APPL NO | 10/420361 |
ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/755 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 07250097 | Antal et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | József Antal (Bethesda, Maryland); Zsuzsanna Buzás (Godollo, Hungary); Andreas Chrambach (Bethesda, Maryland) |
ABSTRACT | An apparatus and method for the sequential electroelution of biomolecules is described, the apparatus comprising a separation medium having an outlet, and a collector having at least a first receptacle and a second receptacle that can be sequentially brought into contact with the outlet of the separation medium by translating the first receptacle and the second receptacle in relation to the outlet of the separation medium, and the method comprising the steps of receiving a first substantially separated molecule in the first receptacle and translating the first receptacle and the second receptacle such that the second receptacle is brought into in contact with the outlet of the separation medium, receiving a second substantially separated molecule in the second receptacle, and repeating said steps to sequentially receive a desired number of substantially separated molecules. |
FILED | Friday, July 09, 2004 |
APPL NO | 10/888075 |
ART UNIT | 1753 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical and wave energy 24/462 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250128 | Unger et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Marc A. Unger (South San Francisco, California); Hou-Pu Chou (Sunnyvale, California); Todd A. Thorsen (Pasadena, California); Axel Scherer (Laguna Beach, California); Stephen R. Quake (San Marino, California); Jian Liu (Pasadena, California); Mark L. Adams (Pasadena, California); Carl L. Hansen (Pasadena, California) |
ABSTRACT | A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate. |
FILED | Wednesday, April 20, 2005 |
APPL NO | 11/111264 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/155 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250154 | Kohn et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Rutgers, The State University (New Brunswick, New Jersey) |
INVENTOR(S) | Joachim B. Kohn (Plainfield, New Jersey); Durgadas Bolikal (Edison, New Jersey); Sanyong M. Pendharkar (Old Bridge, New Jersey) |
ABSTRACT | A radio-opaque dihydroxy compound substituted with at least one bromine or iodine atom. Radio-opaque medical implants and drug delivery devices and methods for therapeutic site-specific or systemic drug delivery comprising implanting in the body of a patient are also disclosed. |
FILED | Tuesday, December 28, 2004 |
APPL NO | 11/024355 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250171 | Tao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as Represented by the Dept. of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Tao Tao (Bethesda, Maryland); Mario H. Skiadopoulos (Potomac, Maryland); Peter L. Collins (Rockville, Maryland); Brian R. Murphy (Bethesda, Maryland) |
ABSTRACT | Chimeric parainfluenza viruses (PIVs) are provided that incorporate a PIV vector genome or antigenome modified to encode a chimeric glycoprotein incorporating one or more heterologous antigenic domains, fragments, or epitopes of a second, antigenically distinct HPIV. These chimeric viruses are infectious and attenuated in humans and other mammals and are useful in vaccine formulations for eliciting an immune responses against one or more PIVs, and, optionally against respiratory syncytial virus (RSV). Also provided are isolated polynucleotide molecules and vectors incorporating a chimeric PIV genome or antigenome which includes a HPIV vector genome or antigenome combined or integrated with one or more heterologous genome segment(s) encoding one or more antigenic determinant(s) of a heterologous PIV to encode a chimeric glycoprotein. In preferred aspects of the invention, the chimeric virus is attenuated for use as a vaccine agent by additional mutations or nucleotide modifications introduced into the chimeric genome or antigenome. |
FILED | Friday, December 10, 1999 |
APPL NO | 09/459062 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/211.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250172 | Apicella et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Michael A. Apicella (Solon, Iowa); Jennifer L. Edwards (Iowa City, Iowa); Bradford W. Gibson (Berkeley, California); Karoline Scheffler (Munich, Germany) |
ABSTRACT | The present invention is directed to novel polypeptides, polynucleotides and vaccines for use against Neisseria gonorrhoeae colonization or infection. The vaccines contain an immunogenic amount of a neisserial protein. |
FILED | Thursday, January 31, 2002 |
APPL NO | 10/066551 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/249.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250251 | Greene et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
INVENTOR(S) | Warner C. Greene (Hillsborough, California); Marielle Cavrois (San Francisco, California); Carlos de Noronha (San Francisco, California) |
ABSTRACT | The present invention features methods and compositions relating to a virion-based fusion assay for detection of infection of a target cell by an enveloped retroviral virion such as HIV. The assay uses virions containing a chimeric viral protein comprising a viral accessory polypeptide (such as Vpr) fused to a reporter polypeptide (such as beta-lactamase). Fusion of the virion with a target cell membrane results in intracellular delivery of the chimeric protein to the target cell, which in turn provides for detection of a detectable signal mediated by the reporter polypeptide portion of the chimeric polypeptide. Significant detectable signal is only detected following intracellular delivery of the chimeric viral protein, thus providing for detection of productive viral entry to the exclusion of non-productive, endocytic entry of virions into the cell. |
FILED | Thursday, September 04, 2003 |
APPL NO | 10/656803 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250261 | Leong et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | John M. Leong (Newton, Massachusetts); Kenneth G. Campellone (Worcester, Massachusetts) |
ABSTRACT | Disclosed are EspFU (EspF-like polypeptide encoded by a gene of the cryptic prophage CP-933U of enterohemorrhagic E. coli) polypeptides, fragments thereof, nucleic acids that encode EspFU polypeptides, or fragments thereof, and cells including the polypeptides, fragments, and/or nucleic acids. Also disclosed are model systems, kits, and methods for screening that use, for example, EspFU polypeptides and nucleic acids. Also included are pharmaceutical and diagnostic compositions and methods of diagnosis and treatment of EHEC infections. |
FILED | Friday, May 20, 2005 |
APPL NO | 11/134563 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250267 | Walt et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | David R. Walt (Lexington, Massachusetts); Caroline L. Schauer (Silver Spring, Maryland); Frank J. Steemers (San Diego, California) |
ABSTRACT | The present invention provides a novel cross-reactive sensor system utilizing cross-reactive recognition elements. In the inventive system, each of said one or more cross-reactive recognition elements is capable of interacting with more than one species of liquid analyte of interest, whereby each of said one or more cross-reactive recognition elements reacts in a different manner with each of said one or more species of liquid analytes of interest to produce a detectable agent of each analyte of interest, whereby said detectable agent is analyzed and the information is processed for data acquisition and interpretation. In certain preferred embodiments, the detectable agent and/or change is detected directly, while in certain other preferred embodiments, the detectable agent and/or change is detected with the help of a transducing agent capable of relaying information about each detectable agent generated for each of said species of liquid analyte of interest, whereby said information is processed for data acquisition and interpretation. The present invention also provides method for the analysis of analytes comprising contacting one or more analytes with the inventive system described above. |
FILED | Wednesday, March 14, 2001 |
APPL NO | 10/221815 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250270 | Goldrick et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Ambion, Inc. (Austin, Texas) |
INVENTOR(S) | Marianna Goldrick (Austin, Texas); Juanita C. Gonzales (Austin, Texas) |
ABSTRACT | The present invention concerns the methods and compositions for preparing a tissue section or biological sample, particularly to preserve RNA in the section or sample, by not exposing or contacting the sample or section to a solution that is composed of mostly water. Tissue sections can be fixed, stained, and dehydrated for subsequent manipulation, including laser capture microdissection (LCM) for further analysis using methods and/or compositions of the invention. |
FILED | Friday, June 13, 2003 |
APPL NO | 10/462091 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/40.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250271 | Waisman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | David Waisman (Calgary, Alberta, Canada); Mijung Kwon (Calgary, Alberta, Canada) |
ABSTRACT | This invention relates generally to methods of producing peptide-based anti-angiogenesis compounds using plasmin reductases, and specifically to methods of producing an A61 anti-angiogenic plasmin fragment using an annexin II heterotetramer or subunit thereof. This invention also relates to anti-angiogenesis methods and compositions comprising a plasmin reductase or polynucleotides encoding subunits thereof. Compositions useful for the inhibition or promotion of angiogenesis are also disclosed. |
FILED | Tuesday, November 26, 2002 |
APPL NO | 10/304287 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250283 | Spiegelman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Dana-Farber Cancer Institute (Boston, Massachusetts) |
INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Guillaume Adelmant (Boston, Massachusetts); Pere Puigserver (Brookline, Massachusetts) |
ABSTRACT | The invention provides isolated nucleic acid molecules, designated PGC-1b and PGC-1c nucleic acid molecules, which encode novel isoforms of PGC-1 family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1 gene has been introduced or disrupted. The invention still further provides isolated PGC-1 proteins, fusion proteins, antigenic peptides and anti-PGC-1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |
FILED | Wednesday, July 03, 2002 |
APPL NO | 10/482094 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250295 | Hart et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Lynn Patrick Hart (Lansing, Michigan); James J. Pestka (East Lansing, Michigan); Qiaoping Yuan (Frederick, Maryland) |
ABSTRACT | The present invention provides transgenic plants cells that express a peptide mimotope of the non-peptide mycotoxin deoxynivalenol. In particular, the peptide mimotope competes with deoxynivalenol for binding to a monoclonal antibody and is antagonistic to the inhibitory effects of deoxynivalenol on in vitro protein synthesis. ransgenic plants expressing the peptide mimotype are resistant to deoxynivalenol. |
FILED | Tuesday, April 09, 2002 |
APPL NO | 10/118708 |
ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/418 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250304 | Fogelman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alan M Fogelman (Beverly Hills, California); Mohamad Navab (Los Angeles, California); Susan Hama (Torrance, California) |
ABSTRACT | This invention provides novel assays that are prognostic and/or diagnostic for atherosclerosis or risk of atherosclerosis. It was discovered that high density lipoprotein (HDL) or components thereof can prevent the oxidation of lipids (e.g., lipids present in LDLs) and can also repair (reduce) already oxidized lipids and thereby reduce the inflammatory response associated with and characteristic of atherosclerotic plaque formation. Moreover it was a discovery of this invention that individuals vary in the ability of their HDL to afford such protection. Thus an assay of HDL protective and/or repair activity provides a highly effective assay for risk of atherosclerosis and its associated pathologies and such assays are provided herein. |
FILED | Monday, February 07, 2005 |
APPL NO | 11/053123 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/71 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250409 | Boger |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Dale L. Boger (La Jolla, California) |
ABSTRACT | Anlogs of ningalin B lacking inherent cytotoxic activity may be employed to reverse multi-drug resistant (MDR) phenotype and to resensitize transformed cells, including a human colon cancer cell line (HCT116/VM46), with respect to a variety of cytotoxic agents, e.g., vinblastine and doxorubicin. In many instances, resensitization is achieved at lower doses than the prototypical agent verapamil. Total synthesis of ningalin B and its analogs was achieved using a concise, efficient approach based on a heterocyclic azadiene Diels-Alder strategy (1,2,4,5-tetrazine→1,2-diazine→pyrrole) ideally suited for construction of the densely functionalized pyrrole core found in the natural product is detailed. |
FILED | Thursday, March 01, 2001 |
APPL NO | 10/204787 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/214.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250437 | Zembower et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Angion Biomedica Corp. (Garden City, New York) |
INVENTOR(S) | David E. Zembower (La Grange, Illinois); David A. Eiznhamer (Bloomingdale, Illinois) |
ABSTRACT | The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role. |
FILED | Wednesday, December 29, 2004 |
APPL NO | 11/024615 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/408 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250492 | Chen |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation at State University of New York (Stony Brook, New York) |
INVENTOR(S) | Wen-Tien Chen (Stony Brook, New York) |
ABSTRACT | The invention provides antibodies that specifically bind a membrane protease complex, the complex consisting of two homodimers of seprase and dipeptidyl peptidase IV (DPPIV), obtained from mammalian, preferably human cell membranes. The antibodies specifically bind the DPPIV protease of the seprase-DPPIV complex. This membrane protease complex resides on cell surface invadopodia at the leading edge of angiogenic endothelia, migratory fibroblasts, and invading cancer cells. The antibodies and immunoconjugates of the invention specifically bind the membrane protease complex at the cell surface invadopodia, yet fail to react with resting cells in adjacent human tissues and blood vessels. These antibodies and immunoconjugates block interaction of collagen matrix with the seprase-DPPIV complex in the invasive cells during angiogenesis and cancer spreading but not that with other endothelia or tumor cells. The invention further provides methods for identifying and of using DPPIV antagonists to inhibit capillary sprouting, angiogenesis and cancer invasion in tumor tissues and metastases. Also provided are therapeutic compositions comprising DPPIV antagonists. |
FILED | Wednesday, December 03, 2003 |
APPL NO | 10/727211 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250499 | Mirkin et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Nanosphere Inc. (Northbrook, Illinois) |
INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Robert L. Letsinger (Wilmette, Illinois); Zhi Li (Evanston, Illinois) |
ABSTRACT | The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids. |
FILED | Tuesday, November 18, 2003 |
APPL NO | 10/716829 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250502 | Cregg |
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APPLICANT(S) | |
ASSIGNEE(S) | Research Corporation Technologies, Inc. (Tucson, Arizona) |
INVENTOR(S) | James M. Cregg (Claremont, California) |
ABSTRACT | The present invention provides formaldehyde dehydrogenase genes (FLD) from methylotrophic yeasts. The FLD structural genes confer resistance to formaldehyde and are therefore useful as a selectable marker in methylotrophic yeasts. The FLD promoter sequences are strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source). Induction under either methanol, methylamine or both provides levels of heterologous gene expression comparable to those obtained with the commonly used alcohol oxidase I gene promoter (PAOX1). The FLD promoter of Pichia pastoris (PFLD1) is an attractive alternative to PAOX1 for expression of foreign genes in P. pastoris, allowing regulation by carbon (methanol) or nitrogen (methylamine) source within the same expression strain. Yeast strains, expression cassettes, expression vectors, and host cells comprising an FLD gene promoter and 3′ termination sequence are also provided. |
FILED | Thursday, June 12, 2003 |
APPL NO | 10/459970 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250504 | Grozinger et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Christina M. Grozinger (Cambridge, Massachusetts); Christian A. Hassig (Berkeley, California); Stuart L. Schreiber (Boston, Massachusetts) |
ABSTRACT | The invention provides histone deacetylase class II nucleic acids and polypeptides, methods and reagents for their use, and related compounds including small molecule libraries containing class II histone deacetylase inhibitors. |
FILED | Wednesday, October 13, 2004 |
APPL NO | 10/964313 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250505 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
INVENTOR(S) | Jonathan A. Cooper (Seattle, Washington); Brian W. Howell (Rockville, Maryland) |
ABSTRACT | A mammalian homology of Drosophila Disabled protein has been identified and cloned. In particular, the murine homolog designated mDab1 has been cloned and expressed. mDab1, when tyrosine phosphorylated, binds to the SH2 domain of Src, Abl and Fyn. Antibodies specific for mDab1 are provided as are methods for the screening of agents for their ability to modulate mDab1 activity. Methods for diagnosing Disabled protein associated disease are also provided. |
FILED | Friday, August 21, 1998 |
APPL NO | 09/486293 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250507 | Bird et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Immunex Corporation (Thousand Oaks, California) |
INVENTOR(S) | Timothy A. Bird (Bainbridge Island, Washington); David J. Cosman (Bainbridge Island, Washington); Xiaoxia Li (Solon, Ohio) |
ABSTRACT | There are disclosed novel polypeptides referred to as Pellino polypeptides, as well as fragments thereof, including immunogenic peptides. DNAs encoding such polypeptides as well as methods of using such DNAs and polypeptides are also disclosed. |
FILED | Wednesday, December 11, 2002 |
APPL NO | 10/317250 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/24.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250551 | Tsai et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Li-Huei Tsai (Cambridge, Massachusetts); Ming-Sum Lee (New York, New York); Jonathan C. Cruz (Boston, Massachusetts) |
ABSTRACT | Disclosed are improved methods of treating individuals with Alzheimer's disease (AD) as well as methods to diagnose AD in an individual. Also included are compounds and methods of identifying compounds to treat AD. The present invention also discloses methods for decreasing the phosphorylation of amyloid precursor protein (APP), including inhibiting phosphorylation of amino acid residue tyrosine 668 of APP and for reducing cleavage of APP. The present invention further discloses transgenic (Tg), non-human animals and cells expressing a p25 transgene that are models of neurodegenerative diseases. Embodiments of the present invention are directed to methods wherein the Tg animals and Tg cells of the invention are used to screen for modulators of neurodegenerative disorders. The Tg animals and cells of the present invention are useful for elucidating the mechanisms of neurodegenerative disorders. |
FILED | Thursday, July 24, 2003 |
APPL NO | 10/625986 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250555 | Pandey et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Girdhar K. Pandey (El Cerrito, California); Rajeev Gupta (Berkeley, California); Kyung-Nam Kim (Seoul, South Korea); Sheng Luan (Kensington, California) |
ABSTRACT | The invention provides novel methods useful for enhancing a stress response in plants. Specifically, the methods of the present invention are useful for increasing the tolerance of a plant to stresses such as hyperthermia, hypothermia, hyperosmolarity, hypoosmolarity, and wounds. |
FILED | Friday, March 15, 2002 |
APPL NO | 10/098306 |
ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/289 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251258 | Wise et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
INVENTOR(S) | Frank W. Wise (Ithaca, New York); Fatih Omer Ilday (Ithaca, New York); Hyungsik Lim (Ithaca, New York) |
ABSTRACT | A photonic-crystal fiber provides dispersion compensation in a soliton fiber laser. The anomalous dispersion provided by the photonic-crystal fiber permits construction of a femtosecond fiber laser at 1 μm wavelength without prisms or diffraction gratings. The laser produces ˜100-fs pulses with 1 nJ energy, and is a major step toward environmentally-stable all-fiber devices at 1 μm. |
FILED | Monday, April 28, 2003 |
APPL NO | 10/423932 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251307 | Chen |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Guang-Hong Chen (Madison, Wisconsin) |
ABSTRACT | A tomographic image reconstruction method produces either 2D or 3D images from fan beam or cone beam projection data by filtering the backprojection image of differentiated projection data. The reconstruction is mathematically exact if sufficient projection data is acquired. A cone beam embodiment and both a symmetric and asymmetric fan beam embodiment are described. |
FILED | Tuesday, November 22, 2005 |
APPL NO | 11/284500 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251353 | Doi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Kunio Doi (Chicago, Illinois); Junji Morishita (Chicago, Illinois); Shigehiko Katsuagawa (Chicago, Illinois) |
ABSTRACT | A method for determining whether a first medical image and a second medical image are medical images of the same patient, comprising selecting a first region in the first medical image; selecting a second region in the second medical image; determining a common region based on a boundary of the first region and a boundary of the second region; calculating a correlation coefficient based on image data from the first medical image in the common region and image data from the second medical image in the common region; and determining whether the first medical image and the second medical image are medical images of the same patient based on the correlation coefficient. Biological fingerprints from parts of chest radiographs such as thoracic fields, cardiac shadows, lung apices, superior mediastinum, and the right lower lung that includes the costophrenic angle, are used for the purpose of patient recognition and identification. |
FILED | Wednesday, February 05, 2003 |
APPL NO | 10/358337 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251609 | McAlindon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Boston University (Boston, Massachusetts) |
INVENTOR(S) | Timothy E. McAlindon (Belmont, Massachusetts); Karim A. N. Kabbara (Weymouth, Massachusetts) |
ABSTRACT | The invention encompasses a method of conducting a clinical trial of a test substance from a primary site, via the internet. The internet is used in various phases of a clinical trial, including: recruiting and screening for candidates who are eligible to participate in a clinical trial of a test substance using the internet; obtaining, directly from a participant at a remote site, personal information as well as information allowing a determination of any effect(s) of the test substance on the participant after use (e.g., by evaluation forms completed and transmitted over the internet); compiling data from multiple participants. |
FILED | Friday, April 28, 2000 |
APPL NO | 09/560597 |
ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07250139 | Espinosa et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Horacio D. Espinosa (Winnetka, Illinois); Nicolaie A. Moldovan (Chicago, Illinois); Keun-Ho Kim (Evanston, Illinois) |
ABSTRACT | A dispensing device has a cantilever comprising a plurality of thin films arranged relative to one another to define a microchannel in the cantilever and to define at least portions of a dispensing microtip proximate an end of the cantilever and communicated to the microchannel to receive material therefrom. The microchannel is communicated to a reservoir that supplies material to the microchannel. One or more reservoir-fed cantilevers may be formed on a semiconductor chip substrate. A sealing layer preferably is disposed on one of the first and second thin films and overlies outermost edges of the first and second thin films to seal the outermost edges against material leakage. Each cantilever includes an actuator, such as for example a piezoelectric actuator, to impart bending motion thereto. The microtip includes a pointed pyramidal or conical shaped microtip body and an annular shell spaced about the pointed microtip body to define a material-dispensing annulus thereabout. The working microtip may be used to dispense material onto a substrate, to probe a surface in scanning probe microscopy, to apply an electrical stimulus or record an electrical response on a surface in the presence of a local environment created around the tip by the material dispensed from the tip or to achieve other functions. |
FILED | Tuesday, March 16, 2004 |
APPL NO | 10/801928 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250147 | Tour et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | James M. Tour (Bellaire, Texas); Jeffrey L. Bahr (Houston, Texas); Jiping Yang (San Jose, California) |
ABSTRACT | The invention incorporates new processes for the chemical modification of carbon nanotubes. Such processes involve the derivatization of multi- and single-wall carbon nanotubes, including small diameter (ca. 0.7 nm) single-wall carbon nanotubes, with diazonium species. The method allows the chemical attachment of a variety of organic compounds to the side and ends of carbon nanotubes. These chemically modified nanotubes have applications in polymer composite materials, molecular electronic applications and sensor devices. The methods of derivatization include electrochemical induced reactions thermally induced reactions (via in-situ generation of diazonium compounds or pre-formed diazonium compounds), and photochemically induced reactions. The derivatization causes significant changes in the spectroscopic properties of the nanotubes. The estimated degree of functionality is ca. 1 out of every 20 to 30 carbons in a nanotube bearing a functionality moiety. Such electrochemical reduction processes can be adapted to apply site-selective chemical functionalization of nanotubes. Moreover, when modified with suitable chemical groups, the derivatized nanotubes are chemically compatible with a polymer matrix, allowing transfer of the properties of the nanotubes (such as, mechanical strength or electrical conductivity) to the properties of the composite material as a whole. Furthermore, when modified with suitable chemical groups, the groups can be polymerized to form a polymer that includes carbon nanotubes |
FILED | Tuesday, January 29, 2002 |
APPL NO | 10/470517 |
ART UNIT | 1754 — Printing/Measuring and Testing |
CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250298 | Glick et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); The University of Washington (Seattle, Washington) |
INVENTOR(S) | Benjamin S. Glick (Chicago, Illinois); Brooke Bevis (Somerville, Massachusetts); Daniel E. Strongin (Chicago, Illinois); David Baker (Seattle, Washington); Michelle Scalley-Kim (Seattle, Washington) |
ABSTRACT | Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use. |
FILED | Thursday, April 07, 2005 |
APPL NO | 11/100988 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/440 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250323 | Gadeken et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York); University of Rochester (Rochester, New York); BetaBatt Inc. (Houston, Texas) |
INVENTOR(S) | Larry L. Gadeken (Houston, Texas); Wei Sun (Rochester, New York); Nazir P. Kherani (Ontario, Canada); Philippe M. Fauchet (Pittsford, New York); Karl D. Hirschman (Henrietta, New York) |
ABSTRACT | A method of making an energy conversion device includes forming a plurality of pores within a substrate and forming a junction region within each of the plurality of pores. Each of the junction regions has a depletion region and each of the plurality of pores defines an opening size in the substrate and a spacing from adjacent pores so that the depletion regions of each of the pores is at least substantially in contact with the depletion region of the pores which are adjacent. |
FILED | Tuesday, October 25, 2005 |
APPL NO | 11/257520 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/56 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250406 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Shiu-Cheng Tang (Atlanta, Georgia); Athanassios Sambanis (Atlanta, Georgia) |
ABSTRACT | The present invention provides compositions and methods for modulating the secretion of transcriptionally regulated proteins from recombinant cells. More particularly, the present invention provides compositions and methods for accelerating the secretion dynamics of human insulin from recombinant cells using nonsense mediated mRNA decay of the preproinsulin mRNA transcript. |
FILED | Monday, April 21, 2003 |
APPL NO | 10/419539 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
07250423 — Methods for synthesizing heterocycles and therapeutic use of the heterocycles for cancers
US 07250423 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Chao-Jun Li (Metairie, Louisiana); Jianheng Zhang (Sunnyvale, California) |
ABSTRACT | The present invention provides methods for synthesizing novel tetrahydroquinoline derivatives that are useful for cancer chemotherapy and anti-viral applications. The present invention provides compounds useful for cancer chemotherapy and methods for the preparation of these compounds. The present invention also includes cancer chemotherapy methods. |
FILED | Tuesday, September 24, 2002 |
APPL NO | 10/254033 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250502 | Cregg |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Research Corporation Technologies, Inc. (Tucson, Arizona) |
INVENTOR(S) | James M. Cregg (Claremont, California) |
ABSTRACT | The present invention provides formaldehyde dehydrogenase genes (FLD) from methylotrophic yeasts. The FLD structural genes confer resistance to formaldehyde and are therefore useful as a selectable marker in methylotrophic yeasts. The FLD promoter sequences are strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source). Induction under either methanol, methylamine or both provides levels of heterologous gene expression comparable to those obtained with the commonly used alcohol oxidase I gene promoter (PAOX1). The FLD promoter of Pichia pastoris (PFLD1) is an attractive alternative to PAOX1 for expression of foreign genes in P. pastoris, allowing regulation by carbon (methanol) or nitrogen (methylamine) source within the same expression strain. Yeast strains, expression cassettes, expression vectors, and host cells comprising an FLD gene promoter and 3′ termination sequence are also provided. |
FILED | Thursday, June 12, 2003 |
APPL NO | 10/459970 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250556 | Wessler et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Washington University (St. Louis, Missouri) |
INVENTOR(S) | Susan R. Wessler (Athens, Georgia); Ning Jiang (Athens, Georgia); Zhirong Bao (Seattle, Washington); Xiaoyu Zhang (Athens, Georgia); Sean R. Eddy (Saint Louis, Missouri) |
ABSTRACT | Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein or a portion of a transposase protein. The isolated transposable elements or the isolated DNA sequences are members of the mPing/Pong family of transposable elements. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable elements are useful in applications such as the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the mPing/Pong family of transposable elements, or for the detection of transpositions of the transposable elements. |
FILED | Thursday, January 16, 2003 |
APPL NO | 10/346198 |
ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250624 | Freedman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Microsoft Corporation (Redmond, Washington) |
INVENTOR(S) | Michael H. Freedman (Redmond, Washington); Chetan V. Nayak (Santa Monica, California) |
ABSTRACT | A quantum computer can only function stably if it can execute gates with extreme accuracy. “Topological protection” is a road to such accuracies. Quasi-particle interferometry is a tool for constructing topologically protected gates. Assuming the corrections of the Moore-Read Model for v= 5/2's FQHE (Nucl. Phys. B 360, 362 (1991)) we show how to manipulate the collective state of two e/4-charge anti-dots in order to switch said collective state from one carrying trivial SU(2) charge, |1>, to one carrying a fermionic SU(2) charge |ε>. This is a NOT gate on the {|1>, |ε>} qubit and is effected by braiding of an electrically charged quasi particle σ which carries an additional SU(2)-charge. Read-out is accomplished by σ-particle interferometry. |
FILED | Friday, September 23, 2005 |
APPL NO | 11/233653 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250729 | Shepherd et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Nigel D. Shepherd (Gainesville, Florida); Rolf E. Hummel (Gainesville, Florida) |
ABSTRACT | The subject invention pertains to a method of spark processing silicon and resulting materials. The subject invention also relates to electroluminescent devices incorporating the materials produced by the subject method. The subject method for spark-processing can enhance the EL output, as compared with conventional spark-processed (sp) silicon. The enhancement of EL output can be due, at least in part, to increasing the light emitting area. The subject method can smooth the sp surface, so as to allow more complete coverage of the sp area with a continuous, semitransparent, conducting film. The smoothening of the sp surface can be accomplished by, for example, introducing into the spark plasma a volatile liquid, such as methanol, ethanol, acetone, in which particles can be suspended and/or in which a heavy ion salt is dissolved. The particles preferably float in the volatile liquid, rather than settle quickly. In a specific embodiment, silicon particles in the range of about 0.2 μm to about 20 μm in size can be suspended in the volatile liquid, such as methanol. The volatile liquid/silicon-particle suspension or volatile liquid/heavy ion salt solution, can then be inserted into a means for applying the mixture to the surface of a silicon wafer during spark-processing. |
FILED | Friday, July 15, 2005 |
APPL NO | 11/182372 |
ART UNIT | 2821 — Optics |
CURRENT CPC | Electric lamp and discharge devices: Systems 315/169.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251263 | Rocca |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
INVENTOR(S) | Jorge J. Rocca (Fort Collins, Colorado) |
ABSTRACT | A compact, high repetition rate, extreme ultraviolet/soft x-ray laser and method for generating such radiation are described. Excitation of the gaseous or vaporous lasing medium is achieved by discharging energy stored in a solid-dielectric capacitive device through a capillary channel containing the medium. By reducing the inductance of the discharge apparatus, excitation of the laser medium can be achieved without the use of Marx generators. Neon-like Ar atom laser pulses at 46.9 nm having energies of about 13 μJ are generated at repetition rates up to 12 Hz. Between 2 and 3×104 laser shots can be generated using a single capillary. Such a source of intense, short-wavelength radiation can be used for applications which include surface characterization of materials, high resolution imaging and printing, photochemistry and photophysics, laser ablation, characterization of x-ray optics, and dense plasma diagnostics. |
FILED | Monday, May 23, 2005 |
APPL NO | 11/136617 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/61 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251768 | Giannakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Georgios B. Giannakis (Minnetonka, Minnesota); Zhengdao Wang (Ames, Iowa); Shengli Zhou (Minneapolis, Minnesota) |
ABSTRACT | In general, joint error-control coding and linear precoding techniques are proposed for fading-resilient transmissions over frequency- at and frequency-selective fading channels encountered with high-rate wireless OFDM transmissions. For example, a wireless communication system includes a transmitter that applies non-linear codes and a linear precoder to a data stream to produce a joint coded-precoded waveform. A receiver receives the joint coded-precoded waveform from the transmitter via a wireless communication channel, and demodulates the joint-coded precoded waveform to produce estimated data. The combination offers a multiplicative benefit to the diversity achievable by the wireless communication system. |
FILED | Monday, April 21, 2003 |
APPL NO | 10/420361 |
ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/755 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251791 | Wang |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Sheng-Guo Wang (Charlotte, North Carolina) |
ABSTRACT | There is provided a set of methods with the exact accuracy to effectively calculate the 2n-th order state space models of RLC distributed interconnect and transmission line in closed forms in time domain and transfer functions by recursive algorithms in frequency domain, where their RLC components can be evenly distributed or variously valued. The main features include simplicity and accuracy of the said closed forms of the state space models {A,B,C,D} without involving matrix inverse and matrix multiplication operations, effectiveness and accuracy of the said recursive algorithms of the transfer functions, dramatic reduction of the calculation complexity to O(n2) for the state space models, simulation methodology, and practice of various model reductions and their optimization. For evenly distributed RLC interconnect and transmission line, the said closed form of state space model has its computation complexity of only a fixed constant, i.e., O(1). |
FILED | Tuesday, January 18, 2005 |
APPL NO | 11/037636 |
ART UNIT | 2825 — Semiconductors/Memory |
CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/1 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07249540 | Hacker et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Scott C. Hacker (League City, Texas); Richard J. Dean (Friendswood, Texas); Scott W. Burge (Friendswood, Texas); Toby W. Dartez (Alvin, Texas) |
ABSTRACT | An adapter for installing a connector to a terminal post, wherein the connector is attached to a cable, is presented. In an embodiment, the adapter is comprised of an elongated collet member having a longitudinal axis comprised of a first collet member end, a second collet member end, an outer collet member surface, and an inner collet member surface. The inner collet member surface at the first collet member end is used to engage the connector. The outer collet member surface at the first collet member end is tapered for a predetermined first length at a predetermined taper angle. The collet includes a longitudinal slot that extends along the longitudinal axis initiating at the first collet member end for a predetermined second length. The first collet member end is formed of a predetermined number of sections segregated by a predetermined number of channels and the longitudinal slot. |
FILED | Friday, July 01, 2005 |
APPL NO | 11/177652 |
ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Tools 081/124.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249768 | Keba |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | John E. Keba (Oak Park, California) |
ABSTRACT | A pressure-actuated shaft seal assembly and associated method for controlling the flow of fluid adjacent a rotatable shaft are provided. The seal assembly includes one or more seal members that can be adjusted between open and closed positions, for example, according to the rotational speed of the shaft. For example, the seal member can be configured to be adjusted according to a radial pressure differential in a fluid that varies with the rotational speed of the shaft. In addition, in the closed position, each seal member can contact a rotatable member connected to the shaft to form a seal with the rotatable member and prevent fluid from flowing through the assembly. Thus, the seal can be closed at low speeds of operation and opened at high speeds of operation, thereby reducing the heat and wear in the seal assembly while maintaining a sufficient seal during all speeds of operation. |
FILED | Friday, May 07, 2004 |
APPL NO | 10/841652 |
ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Seal for a joint or juncture 277/408 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07249928 | Klasing et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Kevin Samuel Klasing (Springboro, Ohio); Scott Michael Carson (Mason, Ohio) |
ABSTRACT | A turbine nozzle for a gas turbine engine includes a nozzle segment having an airfoil-shaped vane with a root, a tip, a leading edge, a trailing edge and opposed curved pressure and suction sides. An arcuate inner band segment is attached to the root of the vane. The inner band segment includes an inner flowpath surface bounded at forward and aft ends thereof by a forward-facing surface and an aft-facing surface, respectively. A convex curved blended corner is formed between the inner flowpath surface and the aft-facing surface. |
FILED | Friday, April 01, 2005 |
APPL NO | 10/907476 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250075 | Vasquez et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Arturo Vasquez (Pasadena, Texas); Kerri L. McCurdy (Pearland, Texas); Karla F. Bradley (Houston, Texas) |
ABSTRACT | A self-regulated water separator provides centrifugal separation of fuel cell product water from oxidant gas. The system uses the flow energy of the fuel cell's two-phase water and oxidant flow stream and a regulated ejector or other reactant circulation pump providing the two-phase fluid flow. The system further uses a means of controlling the water outlet flow rate away from the water separator that uses both the ejector's or reactant pump's supply pressure and a compressibility sensor to provide overall control of separated water flow either back to the separator or away from the separator. |
FILED | Wednesday, June 16, 2004 |
APPL NO | 10/874004 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Gas separation: Processes 095/241 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250147 | Tour et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | James M. Tour (Bellaire, Texas); Jeffrey L. Bahr (Houston, Texas); Jiping Yang (San Jose, California) |
ABSTRACT | The invention incorporates new processes for the chemical modification of carbon nanotubes. Such processes involve the derivatization of multi- and single-wall carbon nanotubes, including small diameter (ca. 0.7 nm) single-wall carbon nanotubes, with diazonium species. The method allows the chemical attachment of a variety of organic compounds to the side and ends of carbon nanotubes. These chemically modified nanotubes have applications in polymer composite materials, molecular electronic applications and sensor devices. The methods of derivatization include electrochemical induced reactions thermally induced reactions (via in-situ generation of diazonium compounds or pre-formed diazonium compounds), and photochemically induced reactions. The derivatization causes significant changes in the spectroscopic properties of the nanotubes. The estimated degree of functionality is ca. 1 out of every 20 to 30 carbons in a nanotube bearing a functionality moiety. Such electrochemical reduction processes can be adapted to apply site-selective chemical functionalization of nanotubes. Moreover, when modified with suitable chemical groups, the derivatized nanotubes are chemically compatible with a polymer matrix, allowing transfer of the properties of the nanotubes (such as, mechanical strength or electrical conductivity) to the properties of the composite material as a whole. Furthermore, when modified with suitable chemical groups, the groups can be polymerized to form a polymer that includes carbon nanotubes |
FILED | Tuesday, January 29, 2002 |
APPL NO | 10/470517 |
ART UNIT | 1754 — Printing/Measuring and Testing |
CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
07250305 — Use of dye to distinguish salt and protein crystals under microcrystallization conditions
US 07250305 | Cosenza et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | UAB Research Foundation (Birmingham, Alabama) |
INVENTOR(S) | Larry Cosenza (Birmingham, Alabama); Terry L. Bray (Birmingham, Alabama); Lawrence J. DeLucas (Birmingham, Alabama); Thomas E. Gester (Birmingham, Alabama); David T. Hamrick (Glencoe, Alabama) |
ABSTRACT | An improved method of screening crystal growth conditions is provided wherein molecules are crystallized from solutions containing dyes. These dyes are selectively incorporated or associated with crystals of particular character thereby rendering crystals of particular character colored and improving detection of the dyed crystals. A preferred method involves use of dyes in protein solutions overlayed by oil. Use of oil allows the use of small volumes of solution and facilitates the screening of large numbers of crystallization conditions in arrays using automated devices that dispense appropriate solutions to generate crystallization trials, overlay crystallization trials with an oil, provide appropriate conditions conducive to crystallization and enhance detection of dyed (colored) or undyed (uncolored) crystals that result. |
FILED | Tuesday, July 30, 2002 |
APPL NO | 10/208576 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/86 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250723 | Foster |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | John E. Foster (Strongsville, Ohio) |
ABSTRACT | A device and method for generating cathode luminescence is provided. The device and method generate broad spectrum electromagnetic radiation in the visible. A layer of particles, such as quartz or alumina powder, is exposed to electrons in a plasma discharge. Surface excitation of these particles or the generations/excitation of F-center sites give rise to luminescence. |
FILED | Tuesday, December 21, 2004 |
APPL NO | 11/016735 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Electric lamp and discharge devices 313/582 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251066 | Chao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Tien-Hsin Chao (Valencia, California); Jay C. Hanan (Monrovia, California); George F. Reyes (Fontana, California); Hanying Zhou (Arcadia, California) |
ABSTRACT | A method, apparatus, and system provide the ability for storing holograms at high speed. A single laser diode emits a collimated laser beam to both write to and read from a photorefractice crystal. One or more liquid crystal beam steering spatial light modulators (BSSLMs) steer a reference beam, split from the collimated laser beam, at high speed to the photorefractive crystal. |
FILED | Friday, August 04, 2006 |
APPL NO | 11/462495 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07250074 | Tonkovich et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Velocys, Inc. (Plain City, Ohio) |
INVENTOR(S) | Anna Lee Tonkovich (Marysville, Ohio); Dongming Qiu (Dublin, Ohio); Terence Andrew Dritz (Worthington, Ohio); Paul Neagle (Westerville, Ohio); Robert Dwayne Litt (Westerville, Ohio); Ravi Arora (Dublin, Ohio); Michael Jay Lamont (Hilliard, Ohio); Kristina M. Pagnotto (Cincinnati, Ohio) |
ABSTRACT | The disclosed invention relates to a process for separating methane or nitrogen from a fluid mixture comprising methane and nitrogen, the process comprising: (A) flowing the fluid mixture into a microchannel separator, the microchannel separator comprising a plurality of process microchannels containing a sorption medium, the fluid mixture being maintained in the microchannel separator until at least part of the methane or nitrogen is sorbed by the sorption medium, and removing non-sorbed parts of the fluid mixture from the microchannel separator; and (B) desorbing the methane or nitrogen from the sorption medium and removing the desorbed methane or nitrogen from the microchannel separator. The process is suitable for upgrading methane from coal mines, landfills, and other sub-quality sources. |
FILED | Thursday, August 26, 2004 |
APPL NO | 10/927370 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Gas separation: Processes 095/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250284 | Allen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Michael S. Allen (Knoxville, Tennessee); Gupta Rakesh (New Delhi, India); Sayler S. Gary (Blaine, Tennessee) |
ABSTRACT | Purified nucleic acids, vectors and cells containing a gene cassette encoding at least one modified bioluminescent protein, wherein the modification includes the addition of a peptide sequence. The duration of bioluminescence emitted by the modified bioluminescent protein is shorter than the duration of bioluminescence emitted by an unmodified form of the bioluminescent protein. |
FILED | Monday, April 19, 2004 |
APPL NO | 10/827133 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250727 | Lewellen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicago Argonne LLC (Chicago, Illinois) |
INVENTOR(S) | John W. Lewellen (Plainfield, Illinois); John Noonan (Naperville, Illinois) |
ABSTRACT | Beam processing methods including e-beam welding and e-beam evaporation for thin film deposition are implemented with a novel high power, long focus electron source. The high power, long focus electron source generates an e-beam. The e-beam is transported through a series of steering magnets to steer the beam. At least one refocusing magnet is provided to refocus the e-beam. A final steering magnet bends the e-beam to focus on a target, such as a weld joint or a deposition target. |
FILED | Thursday, June 02, 2005 |
APPL NO | 11/143417 |
ART UNIT | 2821 — Optics |
CURRENT CPC | Electric lamp and discharge devices: Systems 315/111.410 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251022 | Martin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Rodger C. Martin (Powell, Tennessee); Madhavi Z. Martin (Powell, Tennessee) |
ABSTRACT | Laser-induced breakdown spectroscopy (LIBS) is applied on a microscale for in situ elemental analysis and spatial mapping in biological cells. A high power laser beam is focused onto a cell surface using a dual branching optical fiber probe for optical excitation of the cell constituents. Dual spectrometers and ICCD detectors capture the emission spectra from the excited cell(s). Repeated probing or repositioning of the laser beam with respect to the cell can provide 2-D or 3-D mapping of the cell. |
FILED | Friday, September 30, 2005 |
APPL NO | 11/240264 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/72 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251040 | Eah et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicago Argonne LLC (Chicago, Illinois) |
INVENTOR(S) | Sang-Kee Eah (Darien, Illinois); Xiao-Min Lin (Naperville, Illinois); Gary Wiederrecht (Elmhurst, Illinois) |
ABSTRACT | An interferometer and a method for generating scattered light interference are provided. A beam splitter is provided by a single metal nanoparticle to split an incoming excitation light. Scattered light from the single metal nanoparticle and its mirror image shows interference in both spatial and spectral domains. A mirror modifies the spatial distribution of elastic light scattering of the single metal nanoparticle. A large spectral width of the scattered light enables a distance measurement without scanning the mirror. |
FILED | Friday, January 21, 2005 |
APPL NO | 11/040914 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/498 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07249569 | Mendu et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Embrex, Inc. (Research Triangle Park, North Carolina) |
INVENTOR(S) | Nandini Mendu (Chapel Hill, North Carolina); Molly Bland (Cary, North Carolina); Stephen Wolfe (Chapel Hill, North Carolina); John Hebrank (Durham, North Carolina); Dipak Mahato (Raleigh, North Carolina) |
ABSTRACT | The present invention provides improved methods of injecting an avian egg containing an embryo, preferably an early embryo (e.g., a blastoderm). The methods of the invention may be used to deliver a substance to an egg, remove a sample from an egg, and/or to insert a detector device into an egg to collect information therefrom. In preferred embodiments, the invention is used to deliver a substance to the embryo in ovo. In other preferred embodiments, the invention is used to produce chimeric or transgenic avian embryos in ovo. |
FILED | Friday, August 09, 2002 |
APPL NO | 10/216427 |
ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Animal husbandry 119/6.800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250625 | Ong et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xerox Corporation (Stamford, Connecticut) |
INVENTOR(S) | Beng S. Ong (Mississauga, Canada); Ping Liu (Mississauga, Canada); Yu Qi (Oakville, Canada); Yiliang Wu (Mississauga, Canada) |
ABSTRACT | An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization. |
FILED | Friday, August 20, 2004 |
APPL NO | 10/922662 |
ART UNIT | 2813 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/40 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251089 | Peng |
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APPLICANT(S) | |
ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
INVENTOR(S) | Chubing Peng (Pittsburgh, Pennsylvania) |
ABSTRACT | A data storage system includes a magnetic storage medium and a write head configured to be positioned adjacent the storage medium and. The write head includes a magnetic field source configured to apply a magnetic field to the storage medium and an optical near field coupling structure configured to locally heat the magnetic storage medium with an optical near field proximate the magnetic field applied by the magnetic field source. An overcoat layer on the magnetic storage medium enhances absorption of the optical near field. |
FILED | Friday, January 07, 2005 |
APPL NO | 11/031849 |
ART UNIT | 2627 — Selective Visual Display Systems |
CURRENT CPC | Dynamic magnetic information storage or retrieval 360/59 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07251745 | Koch et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Availigent, Inc. (San Jose, California) |
INVENTOR(S) | Ruppert Koch (Santa Barbara, California); Sanjay Hortikar (Goleta, California); Louise E. Moser (Santa Barbara, California); Peter M. Melliar-Smith (Santa Barbara, California) |
ABSTRACT | Methods of transparent connection failover allowing a remote computer (i.e., a client), to continue to use a network connection to communicate with one of at least two or more other computers (i.e., the backup servers) over a network, when one of the other computers (i.e., the primary server) fails. With the mechanisms of this invention, there is no need for the client to establish a new connection to a backup server when the primary server fails. The failover is preferably executed within a bridge layer between the TCP layer and the IP layer of the server's TCP/IP stack. No modifications are required to the network infrastructure, the client's TCP/IP stack, the client application or the server application. The methods support active or semi-active replication of the server application, and do not require rollback of the application during failover. The invention also provides mechanisms for bringing up new backup servers. |
FILED | Wednesday, June 11, 2003 |
APPL NO | 10/460761 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/11 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07250295 | Hart et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Lynn Patrick Hart (Lansing, Michigan); James J. Pestka (East Lansing, Michigan); Qiaoping Yuan (Frederick, Maryland) |
ABSTRACT | The present invention provides transgenic plants cells that express a peptide mimotope of the non-peptide mycotoxin deoxynivalenol. In particular, the peptide mimotope competes with deoxynivalenol for binding to a monoclonal antibody and is antagonistic to the inhibitory effects of deoxynivalenol on in vitro protein synthesis. ransgenic plants expressing the peptide mimotype are resistant to deoxynivalenol. |
FILED | Tuesday, April 09, 2002 |
APPL NO | 10/118708 |
ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/418 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250559 | Quiros et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
INVENTOR(S) | Carlos Quiros (Davis, California); Genyi Li (Winnipeg, Canada) |
ABSTRACT | Provided are nucleic acid sequences from Brassica oleracea plants that encode enzymes involved in the synthesis of a glucosinolate molecule, including BoGSL-ALK, and BoGSL-ELONG, and methods of their use. The sequences find particular use in modifying the glucosinolate content of a plant. Also provided are primers for these two genes and a third key gene in the glucosinolate pathway, BoGSL-PRO, that can be used for developing molecular markers for assisted selection of plants with specific glucosinolate compositions. Additionally, compositions and methods for a simple, reliable and efficient PCR-based marker system, named sequence-related amplification polymorphism (SRAP), that finds use in the identification of coding sequences in the genome of a plant are provided. |
FILED | Friday, July 05, 2002 |
APPL NO | 10/482951 |
ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/298 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
US 07249881 | Pipe et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Kevin P. Pipe (Coldwater, Michigan); Rajeev J. Ram (Boston, Massachusetts) |
ABSTRACT | A method and apparatus for performing characterization of devices is presented. The characteristic of the device are determined by obtaining a first temperature measurement in a first location of a device, obtaining a second temperature measurement, computing the difference between the temperature measurements and, using the temperatures and/or the temperature difference, a characteristic of the device is determined. |
FILED | Friday, April 29, 2005 |
APPL NO | 11/119093 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Thermal measuring and testing 374/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 07250323 | Gadeken et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York); University of Rochester (Rochester, New York); BetaBatt Inc. (Houston, Texas) |
INVENTOR(S) | Larry L. Gadeken (Houston, Texas); Wei Sun (Rochester, New York); Nazir P. Kherani (Ontario, Canada); Philippe M. Fauchet (Pittsford, New York); Karl D. Hirschman (Henrietta, New York) |
ABSTRACT | A method of making an energy conversion device includes forming a plurality of pores within a substrate and forming a junction region within each of the plurality of pores. Each of the junction regions has a depletion region and each of the plurality of pores defines an opening size in the substrate and a spacing from adjacent pores so that the depletion regions of each of the pores is at least substantially in contact with the depletion region of the pores which are adjacent. |
FILED | Tuesday, October 25, 2005 |
APPL NO | 11/257520 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/56 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07250290 | Thomae et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Bianca A. Thomae (Bay Village, Ohio); Eric D. Wieben (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota); Thomas C. Wood (Rochester, Minnesota) |
ABSTRACT | Isolated ASMT nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as ASMT allozymes. Methods for determining if a mammal is at risk for toxicity from acute or chronic arsenic exposure also are described. |
FILED | Thursday, April 15, 2004 |
APPL NO | 10/824828 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250325 | Janesick et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sarnoff Corporation (Princeton, New Jersey) |
INVENTOR(S) | James Robert Janesick (Huntington Beach, California); Eugene L. Dines (Aliso Viejo, California); Mark S. Muzilla (Riverside, California); Maryn G. Stapelbroek (Santa Ana, California) |
ABSTRACT | An imager, an image sensor included in the imager and a method of fabricating the image sensor are provided. The image sensor having a substrate with front and back sides to produce image data, includes a transparent conductive coating arranged on the back side of the substrate, a first well region of a first conductive type having first and second opposite sides, the first side being arranged adjacent with the front side of the image sensor; and a second well region of a second conductive type, different from the first conductive type and having a deep well region provided adjacent with the second side of the first well region, the transparent conductive coating configured to develop or to receive a first potential and the first well region configured to receive a second potential to substantially deplete a region between the transparent conductive coating and the first well region. |
FILED | Tuesday, June 14, 2005 |
APPL NO | 11/152364 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/73 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250394 | Nedergaard |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Maiken Nedergaard (South Salem, New York) |
ABSTRACT | The present invention relates to a method of treating glial tumors in a subject, which includes providing a glutamate antagonist or a NMDA receptor antagonist and administering the glutamate antagonist or NMDA receptor antagonist to a subject with a glial tumor of the brain or spinal cord under conditions effective to treat the glial tumor. |
FILED | Tuesday, August 20, 2002 |
APPL NO | 10/225396 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250525 | Kung et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Hank F. Kung (Wynnewood, Pennsylvania); Mei-Ping Kung (Wynnewood, Pennsylvania); Zhi-Ping Zhuang (Lansdale, Pennsylvania) |
ABSTRACT | This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits. |
FILED | Tuesday, August 27, 2002 |
APPL NO | 10/228275 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 556/81 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07250920 | Steinbrecher |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secrtary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Donald H. Steinbrecher (Brookline, Massachusetts) |
ABSTRACT | An electromagnetic radiation interface is provided that is suitable for use with radio wave frequencies. A surface is provided with a plurality of electrically conductive bristles. A corresponding plurality of termination sections are provided so that each bristle is terminated with a termination section. The termination section may comprise one or more different termination packages for operating on received electromagnetic radiation and/or producing desired reflections and transmissions. In one embodiment, switches and termination packages may be implemented within integrated circuits wherein the switches may be utilized to switch between different termination packages. The termination packages may include selected fixed reactances and/or modulators designed to produce desired reflections, e.g., Doppler effects to make it appear the surface of the interface is moving a speed different than the actual speed. |
FILED | Wednesday, September 29, 2004 |
APPL NO | 10/956527 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/853 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 31, 2007.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2007/fedinvent-patents-20070731.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page