FedInvent™ Patents
Patent Details for Tuesday, December 25, 2007
This page was updated on Sunday, March 26, 2023 at 08:46 PM GMT
Department of Health and Human Services (HHS)
| US 07311911 | Varner |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judith A. Varner (Encinitas, California) |
| ABSTRACT | The present invention provides methods for reducing or inhibiting angiogenesis in a tissue, by contacting α5β1 integrin in the tissue with an agent that interferes with the specific binding of α5β1 integrin to a ligand expressed in the tissue; and methods of identifying angiogenesis in a tissue, by contacting the tissue with an agent that specifically binds α5β1 integrin, and detecting specific binding of the agent to α5β1 integrin associated with a blood vessel in the tissue. Also provided are methods of diagnosing a pathological condition characterized by angiogenesis in a tissue in an individual; methods of reducing or inhibiting angio genesis in a tissue in an individual; and methods of reducing the severity of a pathological condition associated with angiogenesis in an individual, by administering to the individual an agent that interferes with specific binding of α5β1 integrin to a ligand in a tissue associated with the pathological condition. |
| FILED | Tuesday, October 14, 2003 |
| APPL NO | 10/685665 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311916 | Wild et al. |
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| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Panacos Pharmaceuticals, Inc. (Gaitherburg, Maryland) |
| INVENTOR(S) | Carl T. Wild (Gaithersburg, Maryland); Carol D. Weiss (Bethesda, Maryland) |
| ABSTRACT | The present invention is directed to the induction and characterization of a humoral immune response targeting “entry-relevant” gp41 structures. In its broadest aspect, the present invention is directed to methods of raising a neutralizing antibody response to a broad spectrum of HIV strains and isolates. The present invention targets particular molecular conformations or structures that occur at the cell surface of HIV during viral entry into host cells. Such a humoral response can be generated in vivo as a prophylactic measure in individuals to reduce or inhibit the ability of HIV to infect uninfected cells in the individual's body. Such a response can also be employed to raise antibodies against “entry relevant” gp41 structures. These antibodies can be employed for therapeutic uses, and as tools for further illuminating the mechanism of HIV cell entry. |
| FILED | Wednesday, September 10, 2003 |
| APPL NO | 10/660206 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/188.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311920 | Devico et al. |
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| ASSIGNEE(S) | University of Maryland Biotechnology Institute (Baltimore, Maryland) |
| INVENTOR(S) | Anthony Louis Devico (Alexandria, Virginia); Timothy R. Fouts (Columbia, Maryland); Robert G. Tuskan (Keymar, Maryland) |
| ABSTRACT | The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can interact with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties characteristic of a receptor-coat protein complex and are useful as agents that inhibit virus infection of cells due to occupancy of co-receptor present on the cell, for example. In particular aspects, the chimeric polypeptide includes an immunodeficiency virus envelope polypeptide, such as that of HIV, SIV, FIV, FeLV, FPV and herpes virus. Receptor sequences suitable for use in a chimeric polypeptide include, for example, CCR5 and CXCR4 sequences. |
| FILED | Friday, October 06, 2000 |
| APPL NO | 09/684026 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311921 | Yamamoto |
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| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Janet K. Yamamoto (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to novel methods and compositions for protecting cats from infection by a broad range of FIV strains using a multi-subtype FIV vaccine. Multi-subtype FIV vaccines comprising either cell free whole virus or cell lines infected with viruses are described. Methods for vaccinating cats with the subject vaccine compositions are also described. Cats vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with homologous or heterologous strains of FIV. The subject invention also pertains to novel feline cell lines that are susceptible to infection by FIV and their methods of use. |
| FILED | Wednesday, August 06, 2003 |
| APPL NO | 10/636079 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312026 | Kruh et al. |
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| ASSIGNEE(S) | Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gary Kruh (Philadelphia, Pennsylvania); Kun Lee (Cranbury, New Jersey); Martin Belinsky (Warminster, Pennsylvania); Lisa Bain (Townville, South Carolina) |
| ABSTRACT | Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells. |
| FILED | Monday, July 12, 2004 |
| APPL NO | 10/889503 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312031 | Muenk et al. |
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| ASSIGNEE(S) | The Salk Institute for Biological Studies (San Diego, California) |
| INVENTOR(S) | Carsten Muenk (Frankfurt, Germany); Anne Holland (San Diego, California); Nathaniel Landau (San Diego, California) |
| ABSTRACT | The present invention relates to the use of an alpha complementation assay as a quick, effective, and safe method for the detection of cell fusion mediated by viral proteins. Additionally, the method disclosed herein permits the identification of inhibitors of cell fusion using an alpha complementation assay. |
| FILED | Thursday, December 04, 2003 |
| APPL NO | 10/729069 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312032 | Htun et al. |
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| ASSIGNEE(S) | Han Htun (Los Angeles, California); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Han Htun (Los Angeles, California); Gordon Hager (Garrett Park, Maryland) |
| ABSTRACT | The present invention provides a method of screening for a compound that binds to a selected nucleic acid comprising contacting compound fluorescently labeled by a fluorescent protein with a cell having a plurality of copies of the nucleic acid in an array such that the nucleic acid can be directly detected when bound by fluorescently labeled compound; and directly detecting the location of fluorescence within the cell, fluorescence aggregated at the site of the nucleic acid array indicating a compound that binds to the selected nucleic acid. In particular compounds such a transcription factors can be screened. Reagents for such method are provided including a mammalian cell having a plurality of steroid receptor response elements in an array such that the response element can be directly detected when bound by fluorescently labeled steroid receptor and a chimeric protein comprising a fluorescent protein fused to a steroid receptor. |
| FILED | Thursday, November 15, 2001 |
| APPL NO | 10/001486 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312037 | Aguirre et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Gustavo Aguirre (Philadelphia, Pennsylvania); Gregory M. Acland (Kennett Square, Pennsylvania); Barbara Zangerl (Philadelphia, Pennsylvania); Orly Goldstein (Ithaca, New York); Susan Pearce-Kelling (Berkshire, New York); Jeanette S. Felix (Horseheads, New York); Duska J. Sidjanin (Brookfield, Wisconsin) |
| ABSTRACT | Tools and methods are provided for determining whether or not a dog is genetically normal, is a carrier of, or is affected with or predisposed to progressive rod-cone degeneration. The method is based on the detection of a transversion from G to A at position corresponding to nucleotide position 1298 of SEQ ID NO: 1. |
| FILED | Tuesday, June 21, 2005 |
| APPL NO | 11/157743 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312038 | Rothschild et al. |
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| ASSIGNEE(S) | The Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth J. Rothschild (Newton, Massachusetts); Sanjay M. Sonar (Boston, Massachusetts); Jerzy Olejnik (Allston, Massachusetts) |
| ABSTRACT | This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates, label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. Useful compositions include biological agents such as nucleic acids, proteins, lipids and cytokines. Conjugates can also be used to monitor the pathway and half-life of pharmaceutical composition in vivo and for diagnostic, therapeutic and prophylactic purposes. The invention also relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and nearly any individual substance in a complex background of substances. |
| FILED | Thursday, January 05, 2006 |
| APPL NO | 11/326021 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312039 | Barany et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Regents of the University of Minnesota (Minneapolis, Minnesota); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Francis Barany (New York, New York); Matthew Lubin (Rye Brook, New York); George Barany (Falcon Heights, Minnesota); Robert P. Hammer (Baton Rouge, Louisiana) |
| ABSTRACT | The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain reaction (PCR) mixture, detecting the amplified ligation product, and identifying the target nucleotide sequence. Such coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence differences. |
| FILED | Tuesday, October 31, 2006 |
| APPL NO | 11/590056 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312041 | Lu et al. |
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| ASSIGNEE(S) | Arbor Vita Corporation (Sunnyvale, California) |
| INVENTOR(S) | Peter S. Lu (Mountain View, California); Johannes Schweizer (Mountain View, California); Chamorro Somoza Diaz-Sarmiento (Palo Alto, California); Michael P. Belmares (San Jose, California) |
| ABSTRACT | The invention provides reagents and methods for detecting pathogen infections in human samples. This detection utilizes specific proteins to detect the presence of pathogen proteins or abnormal expression of human proteins resulting from pathogen infections. Specific methods, compositions and kits are disclosed herein for the detection of oncogenic Human papillomavirus E6 proteins in clinical samples. |
| FILED | Tuesday, July 29, 2003 |
| APPL NO | 10/630590 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312044 | Marks |
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| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Andrew R. Marks (Larchmont, New York) |
| ABSTRACT | This invention provides methods of treating defective skeletal muscle function during heart failure and methods for identifying compounds useful in such treatments. |
| FILED | Friday, March 05, 2004 |
| APPL NO | 10/794218 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312050 | Hageman et al. |
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| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Gregory S. Hageman (Coralville, Iowa); Markus H. Kuehn (Amana, Iowa) |
| ABSTRACT | Methods and compositions for treating ocular disorders such as retinal detachment and macular degeneration and methods and compositions for prognosing or diagnosing retinal detachment or macular degeneration in a subject are disclosed. |
| FILED | Thursday, November 08, 2001 |
| APPL NO | 10/007270 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312059 | Loeb et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Lawrence A. Loeb (Bellevue, Washington); Leroy Hood (Seattle, Washington); Motoshi Suzuki (Nogoya, Japan) |
| ABSTRACT | The present invention provides a method for identifying a thermostable polymerase having altered fidelity. The method consists of generating a random population of polymerase mutants by mutating at least one amino acid residue of a thermostable polymerase and screening the population for one or more active polymerase mutants by genetic selection. For example, the invention provides a method for identifying a thermostable polymerase having altered fidelity by mutating at least one amino acid residue in an active site O-helix of a thermostable polymerase. The invention also provides thermostable polymerases and nucleic acids encoding thermostable polymerases having altered fidelity, for example, high fidelity polymerases and low fidelity polymerases. The invention additionally provides a method for identifying one or more mutations in a gene by amplifying the gene with a high fidelity polymerase. The invention further provides a method for accurately copying repetitive nucleotide sequences using a high fidelity polymerase mutant. The invention also provides a method for diagnosing a genetic disease using a high fidelity polymerase mutant. The invention further provides a method for randomly mutagenizing a gene by amplifying the gene using a low fidelity polymerase mutant. |
| FILED | Thursday, March 31, 2005 |
| APPL NO | 11/096645 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312064 | Hoffmann |
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| ASSIGNEE(S) | St. Jude Children's Research Hosptal (Memphis, Tennessee) |
| INVENTOR(S) | Erich Hoffmann (Memphis, Tennessee) |
| ABSTRACT | The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus. Attenuated or inactivated RNA viruses produced by the present invention may be administered to a patient in need of vaccination by any of several routes including intranasally or intramuscularly. |
| FILED | Tuesday, March 29, 2005 |
| APPL NO | 11/093430 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312066 | Mahajan et al. |
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| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Muktar A. Mahajan (New York, New York); Herbert H. Samuels (New Rochelle, New York) |
| ABSTRACT | The present invention relates to isolated human and rat nucleic acid molecules encoding a protein or polypeptide that modulates transcriptional activation in a cell with or without collaboration with a nuclear hormone receptor transcriptional co-activator. The present invention also relates to the proteins or polypeptides encoded by those nucleic acid molecules, and antibodies against such proteins or polypeptides. The present invention also relates to a variety of uses for the nucleic acid molecules, proteins or polypeptides, and the related antibodies of the present invention, including methods of: regulating cellular proliferation, differentiation, and development; modulating the activity of a transcriptional co-activator complex and a transcription factor in cells; regulating hormone receptor activity and endocrine function in cells; and treating diabetes and insulin resistance in a subject. |
| FILED | Wednesday, August 20, 2003 |
| APPL NO | 10/645250 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312081 | Jessell et al. |
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| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); The Regents of the University of California (Alameda, California) |
| INVENTOR(S) | Thomas M. Jessell (Bronx, New York); James Briscoe (London, United Kingdom); Johan Ericson (Hasselby, Sweden); John L. R. Rubenstein (San Francisco, California); Maike Sander (Hamburg, Germany) |
| ABSTRACT | This invention provides a method of converting a stem cell into a ventral neuron which comprises introducing into the stem cell a nucleic acid which expresses homeodomain transcription factor Nkx6.1 or Nkx6.2 protein in the stem cell so as to thereby convert the stem cell into the ventral neuron. Provided are methods of diagnosing a motor neuron degenerative disease in a subject. Also provides is a method of treating neuronal degeneration in a subject which comprises implanting in diseased neural tissue of the subject a neural stem cell which is capable of expressing homeodomain Nkx6.1 or Nkx6.2 protein under conditions such that the stem cell is converted into a motor neuron after implantation, thereby treating neuronal degeneration in the subject. |
| FILED | Friday, August 31, 2001 |
| APPL NO | 10/362437 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312088 | Farquharson |
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| ASSIGNEE(S) | Real-Time Analyzers, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Stuart Farquharson (Meriden, Connecticut) |
| ABSTRACT | Apparatus for use in effecting surface-enhanced Raman spectroscopy comprises first and second containment means, the first containment means containing a known quantity of a reference chemical having an effective surface-enhanced Raman factor, and the second containment means containing a surface-enhanced Raman-active medium and being sufficiently transparent, at least at one optical access location, to permit both the excitation irradiation of, and also the collection of surface-enhanced Raman scattered radiation from, a common field of view of the surface-enhanced Raman-active medium. The apparatus is constructed for carrying out the method of the invention; i.e., for effecting intimate mixing, substantially prior to introduction to the surface-enhanced Raman-active medium contained in the second containment means, of the reference chemical with an analyte chemical-containing solution introduced through an entrance into the first containment means. The homogeneous test solution so formed permeates the SER-active material in the second containment means, which is irradiated at the common field of view so as to produce SER scattered radiation for collection and quantitative analysis. |
| FILED | Thursday, July 29, 2004 |
| APPL NO | 10/902511 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312197 | Gong et al. |
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| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Da-Wei Gong (Olney, Maryland); John McLenithan (Baltimore, Maryland); Alan Shuldiner (Columbia, Maryland); Rongze Yang (Baltimore, Maryland) |
| ABSTRACT | Isolated omentin polypeptides that selectively express in omental fat tissue and methods for the use of the polypeptides. The polypeptides can be used in a method for modifying insulin action and/or glucose metabolism in an animal. The polypeptides can be used to promote glucose uptake by animal adipocytes and other cells, tissues, and/or organs. The polypeptides can also used to provide a therapeutic treatment for diseases of or related to glucose metabolism and adipose tissues. The polypeptides are also incorporated into diagnostic tests and testing kits for diagnosing or detecting a disease or condition involving animal tissue that contains, uses, or expresses the polypeptide in an animal suspected of having the disease or condition. |
| FILED | Tuesday, February 24, 2004 |
| APPL NO | 10/785720 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312226 | Hurley et al. |
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| ASSIGNEE(S) | Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona); Montigen Pharmaceuticals, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Laurence H. Hurley (Tucson, Arizona); Daruka Mahadevan (Tucson, Arizona); David J. Bearss (Cedar Hills, Utah); Hariprasad Vankayalapati (Salt Lake City, Utah); Sridevi Bashyam (Tucson, Arizona); Steven L. Warner (Tucson, Arizona) |
| ABSTRACT | Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof. |
| FILED | Tuesday, March 29, 2005 |
| APPL NO | 11/092168 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/267 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312228 | Cushman et al. |
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| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mark S. Cushman (West Lafayette, Indiana); Yves G. Pommier (Bethesda, Maryland) |
| ABSTRACT | The synthesis and biological activity of benzoisoindoloisoquinolone compounds are described. The synthesis and biological activity of C-11-substituted indenoisoquinolones are also described. Indenoisoquinolones substituted at C-11 are prepared by McMurry reactions of 11-ketoindenoisoquinolones with aldehydes. |
| FILED | Tuesday, May 11, 2004 |
| APPL NO | 10/553532 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312240 | Kingston et al. |
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| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia); Binghamton University (Binghamton, New York); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | David George Ian Kingston (Blacksburg, Virginia); Thota Ganesh (Blacksburg, Virginia); James Patrick Synder (Atlanta, Georgia); Ami S. Lakdawala (Philadelphia, Pennsylvania); Susan Lynn Bane (Vestal, New York) |
| ABSTRACT | Constrained paclitaxel derivatives include a bridge extending from the C-3′ phenyl to either the C4 or -3 positions. Many of the constrained paclitaxel derivatives provide activity comparable or superior to the natural product paclitaxel. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/035037 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/449 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312246 | Hamilton et al. |
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| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Andrew D. Hamilton (Guilford, Connecticut); Justin Ernst (San Diego, California); Brendan Orner (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to compounds and pharmaceutical compositions which are proteonaimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention. In particular, the invention relates to treatment of viral infections using terphenyl derivatives. |
| FILED | Tuesday, January 25, 2005 |
| APPL NO | 11/043697 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/533 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312325 | Sullenger et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Christopher P. Rusconi (Durham, North Carolina) |
| ABSTRACT | RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed. |
| FILED | Wednesday, September 26, 2001 |
| APPL NO | 09/963827 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312335 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Li Deng (Newton, Massachusetts); Hongming Li (Waltham, Massachusetts) |
| ABSTRACT | One aspect of the present invention relates to quinine-based and quinidine-based catalysts. Another aspect of the invention relates to a method of preparing a derivatized quinine-based or quinidine-based catalyst comprising 1) reacting quinine or quinidine with base and a compound that has a suitable leaving group, and 2) converting the ring methoxy group to a hydroxy group. Another aspect of the present invention relates to a method of preparing a chiral, non-racemic compound from a prochiral electron-deficient alkene or azo compound or prochiral aldehyde or prochiral ketone, comprising the step of: reacting a prochiral electron-deficient alkene or azo compound or prochiral aldehyde or prochiral ketone with a nucleophile in the presence of a catalyst; thereby producing a chiral, non-racemic compound; wherein said catalyst is a derivatized quinine or quinidine. Another aspect of the present invention relates to a method of kinetic resolution, comprising the step of: reacting racemic chiral alkene with a nucleophile in the presence of a derivatized quinine or quinidine. |
| FILED | Friday, May 27, 2005 |
| APPL NO | 11/140574 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/135 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312361 | Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Jeffery W. Kelly (La Jolla, California); Steven M. Johnson (San Diego, California); H. Michael Petrassi (Cardiff, California) |
| ABSTRACT | Bisaryloxime ethers and bisarylhydroazones are shown to be effective for inhibiting formation of amyloid fibrils of transthyretin. |
| FILED | Wednesday, February 08, 2006 |
| APPL NO | 11/350664 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312444 | Willougbhy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Chem - Space Associates, Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Ross Clark Willougbhy (Pittsbugh, Pennsylvania); Edward William Sheehan (Pittsbugh, Pennsylvania) |
| ABSTRACT | The present invention relates to an apparatus and method for focusing, separating, and detecting gas-phase ions using the principles of electrohydrodynamic quadrupole fields at high pressures, at or near atmospheric pressure. Ions are entrained in a concentric flow of gas and travel through a high-transmission element into a RF/DC quadrupole, exiting out of the RF/DC quadrupole, and then impacting on an ion detector, such as a faraday plate; or through an aperture or capillary tube with subsequent identification by a mass spectrometer. Ions with stable trajectories pass through the RF/DC quadrupole while ions with unstable trajectories drift off-axis collide with the rods and are lost. Alternatively, detection of ions with unstable trajectories can be accomplished by allowing the ions to pass through the rods and be detected by an off-axis detector. Embodiments of this invention are devices and methods for focusing, separating, and detecting gas-phase ions at or near atmospheric pressure, when coupled to mass spectrometers. |
| FILED | Tuesday, May 24, 2005 |
| APPL NO | 11/135769 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/293 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313427 | Benni |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CAS Medical Systems, Inc. (Branford, Connecticut) |
| INVENTOR(S) | Paul Benni (Middletown, Connecticut) |
| ABSTRACT | A non-invasive near infrared spectrophotometric monitoring transducer assembly includes a housing member, which is adhered directly on a patient's skin. The housing member contains a prism coupled to a flexible and lightweight single core optical light guide, which provides a means of transferring narrow spectral bandwidth light from multiple distant laser diodes of different wavelengths by use of a multi-fiber optic light combining assembly. Different wavelengths are needed to monitor the level of blood oxygenation in the patient. The assembly also contains a planar light guide mounted on the prism located in the housing member, which light guide contacts the patient's skin when the housing member is adhered to the patient's skin. The light guide controls the spacing between the prism and the patient's skin, and therefore controls the intensity of the area on the patient's skin which is illuminated by the laser light. The housing member contains a photodiode assembly, which detects the infrared light at a second location on the skin to determine light absorption. The photodiode assembly is preferably shielded from ambient electromagnetic interference (EMI) by an optically transparent EMI attenuating window. This rigid window placed over the photodiode also provides a planar interface between the assembly and the skin, improving optical coupling and stability as well as reducing the capacitive coupling between skin and the photodiode resulting in further EMI attenuation. The housing may be associated with a disposable sterile hydrogel coated adhesive envelope, or pad, which when applied to the patient's skin will adhere the housing to the patient's skin. The transducer assembly will thus be reusable, and skin-contacting part of the device, i.e., the envelope or pad can be discarded after a single use. The assembly also includes a laser safety interlock means, which is operable to turn off the laser light output in the event that the assembly accidentally becomes detached from the patient's skin. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/384615 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/344 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313482 | Drlica et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Public Health Research Institute of the city of New York, Inc. (Newark, New Jersey) |
| INVENTOR(S) | Karl Drlica (New York, New York); Jian-Ying Wang (Piscataway, New Jersey) |
| ABSTRACT | Nucleic acid hybridization under steady-state conditions is described by a kinetic model in which the intermediate state is assumed to be locally single stranded. An expression was derived that relates nucleic acid secondary structure to the rate of oligonucleotide-RNA hybridization. The model allows the calculation of a rate factor that is proportional to the rate constant for hybridization between complementary nucleic acids and is generally applicable to any RNA molecule with potential utility for rapid identification of sites for antisense attack of mRNA. |
| FILED | Wednesday, May 15, 2002 |
| APPL NO | 10/478049 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07310952 | Howell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Stephen John Howell (West Newbury, Massachusetts); John Carl Jacobson (Melrose, Massachusetts); Timothy P. McCaffrey (Swampscott, Massachusetts); Barry Francis Barnes (Malden, Massachusetts) |
| ABSTRACT | A method facilitates assembling a combustor for a gas turbine engine, wherein the combustor includes a swirler assembly. The method comprises machining material to form a domeplate, positioning a sealplate including an overhanging portion against the domeplate, securing the sealplate in position relative to the domeplate with a welding process, and welding the swirler assembly to the domeplate. |
| FILED | Friday, October 17, 2003 |
| APPL NO | 10/688754 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/796 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311175 | Proscia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | William Proscia (Marlborough, Connecticut); Christopher D. Jones (Thomaston, Connecticut) |
| ABSTRACT | An acoustic liner 20 includes a remote panel 26, a proximate panel 28 transversely spaced from the remote panel and a resonator chamber 34b residing between the panels. Perforations 38 penetrate the proximate panel in registration with the resonator chamber 34b. A neck 56 with an inlet 58 recessed from the proximate panel establishes communication between the chamber and a fluid stream G flowing past the proximate panel. A bypass coolant passage 66 guides coolant through the perforations without guiding it through the resonator chamber. |
| FILED | Wednesday, August 10, 2005 |
| APPL NO | 11/200617 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Acoustics 181/290 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311496 | Steinbrecher |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Donald H Steinbrecher (Brookline, Massachusetts) |
| ABSTRACT | Apparatus for generating electrical energy in a fluid environment, the apparatus including a wing member for disposition in the fluid and pivotally movable about an axis in response to flow of the fluid thereabout, connector rods each pivotally mounted at a first end thereof on the wing on opposite sides of the axis, a crank member attached to a second end of each of the connector rods and rotatable about a pivot axis by movement of the attached connector rod, a housing supporting the wing member, a gear system disposed in the housing, an axle interconnecting each of the crank members and the gear system, and an electrical generator disposed in the housing and driven by the gear system. |
| FILED | Monday, March 14, 2005 |
| APPL NO | 11/081895 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311752 | Tepper et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Argonide Corporation (Sanford, Florida) |
| INVENTOR(S) | Frederick Tepper (Sanford, Florida); Leonid A. Kaledin (Port Orange, Florida) |
| ABSTRACT | The invention is a filter for gaseous media in which nano alumina fibers and second fibers are arranged in a matrix to create asymmetrical pores. The filter is a high efficiency, high capacity particulate filter that intercepts pathogens and other particulate matter from gaseous media, including vapor-suspended particles. The new filter has an improved retention of water-aerosolized particles as compared to conventional HEPA filters and may be used as a pre-filter that extends the life of HEPA filters by about five to ten times. The invention is also a method of manufacturing and using the filter. |
| FILED | Tuesday, September 12, 2006 |
| APPL NO | 11/531107 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas separation 055/528 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311764 | Friday et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Avon Protection Systems, Inc. (Cadillac, Michigan) |
| INVENTOR(S) | David K. Friday (Cockeysville, Maryland); John Schlaechter (Columbus, Ohio); Wayne E. Ballantyne (Columbus, Ohio); Robert J. Puhala (Frederick, Maryland); David W. Pike (Salisbury, United Kingdom) |
| ABSTRACT | A filter for a gas mask has an elliptical or circular, convex shape to conform to the curvature of the wearer's face, or a planar shape. The filter comprises a double particulate filter element and a double adsorption filter element configured for axial airflow therethrough with a bifurcated flow pattern. The adsorption filter element comprises a granulated charcoal, a composite material having carbon particles combined with binder particles, or an immobilized bed of charcoal granules and EVA-coated fibers. |
| FILED | Friday, April 25, 2003 |
| APPL NO | 10/512540 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas separation: Apparatus 096/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311944 | Sambasivan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Applied Thin Films, Inc. (Evanston, Illinois) |
| INVENTOR(S) | Sankar Sambasivan (Chicago, Illinois); Kimberly A. Steiner (Chicago, Illinois); Krishnaswamy K. Rangan (Evanston, Illinois) |
| ABSTRACT | Aluminophosphate compounds and compositions as can be used for substrate or composite films and coating to provide or enhance, without limitation, planarization, anti-biofouling and/or anti-microbial properties. |
| FILED | Tuesday, December 23, 2003 |
| APPL NO | 10/745955 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311962 | Fink et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yoel Fink (Cambridge, Massachusetts); Shandon Hart (Cambridge, Massachusetts); Garry Maskaly (North Quincy, Massachusetts); Burak Temelkuran (Boston, Massachusetts) |
| ABSTRACT | A mirror structure includes a plurality of features of a defined size. The features include alternating spatial units of a chalcogenide glass and a thermoplastic polymer, and are specifically arranged in an ordered form so that the structure is highly reflective. Thermally-assisted methods are introduced for forming such structures. |
| FILED | Tuesday, July 16, 2002 |
| APPL NO | 10/196403 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312036 | Sampath et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ISIS Pharmaceuticals, Inc. (Carlsbad, California) |
| INVENTOR(S) | Rangarajan Sampath (San Diego, California); Thomas A. Hall (Oceanside, California); Mark W. Eshoo (Solana Beach, California) |
| ABSTRACT | The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses that cause viral hemorrhagic fevers by amplification of a segment of viral nucleic acid followed by molecular mass analysis. |
| FILED | Monday, March 21, 2005 |
| APPL NO | 11/085320 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312038 | Rothschild et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth J. Rothschild (Newton, Massachusetts); Sanjay M. Sonar (Boston, Massachusetts); Jerzy Olejnik (Allston, Massachusetts) |
| ABSTRACT | This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates, label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. Useful compositions include biological agents such as nucleic acids, proteins, lipids and cytokines. Conjugates can also be used to monitor the pathway and half-life of pharmaceutical composition in vivo and for diagnostic, therapeutic and prophylactic purposes. The invention also relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and nearly any individual substance in a complex background of substances. |
| FILED | Thursday, January 05, 2006 |
| APPL NO | 11/326021 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312100 | Bocian et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The North Carolina State University (Raleign, North Carolina) |
| INVENTOR(S) | David F. Bocian (Riverside, California); Werner G. Kuhr (Oak Hills, California); Jonathan S. Lindsey (Raleigh, North Carolina); Veena Misra (Raleigh, North Carolina) |
| ABSTRACT | This invention pertains to methods assembly of organic molecules and electrolytes in hybrid electronic. In one embodiment, a method is provided that involves contacting a surface/electrode with a compound of formula: R-L2-M-L1-Z1 where Z1 is a surface attachment group; L1 and L2 are independently linker or covalent bonds; M is an information storage molecule; and R is a protected or unprotected reactive site or group; where the contacting results in attachment of the redox-active moiety to the surface via the surface attachment group; and ii) contacting the surface-attached information storage molecule with an electrolyte having the formula: J-Q where J is a charged moiety (e.g., an electrolyte); and Q is a reactive group that is reactive with the reactive group (R) and attaches J to the information storage molecule thereby patterning the electrolyte on the surface. |
| FILED | Friday, April 30, 2004 |
| APPL NO | 10/837028 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312182 | Tauber et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Arthur Tauber (Elberon, New Jersey); Robert D. Finnegan (West Long Branch, New Jersey); William D. Wilber (Neptune, New Jersey); Steven C. Tidrow (Silver Springs, Maryland); Donald W. Eckart (Wall, New Jersey); William C. Drach (West Long Branch, New Jersey) |
| ABSTRACT | Rare earth metal containing compounds of the formula Sr2LuSbO6 and Sr2LaSbO6 have been prepared as high critical temperature thin film superconductor structures, and can be used in other ferroelectrics, pyroelectrics, piezoelectrics, and hybrid device structures. |
| FILED | Thursday, March 11, 2004 |
| APPL NO | 10/801166 |
| ART UNIT | 1754 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/125 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312202 | Johnston et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Stephen Johnston (Dallas, Texas); Bao-Xi Qu (Plano, Texas) |
| ABSTRACT | The present invention relates to chemically synthesized promoters that circumvent the disadvantages of the universal CMV promoter/enhancer elements. The promoter may be used in a variety of applications, particularly in genetic immunization. The chemically synthesized promoter overcomes the common problems of the CMV promoter element such as: low transgene expression levels, transient expression, and the large amount of plasmid DNA needed for intramuscular injection in subjects. |
| FILED | Wednesday, February 18, 2004 |
| APPL NO | 10/781055 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312412 | Cravey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alpha-Omega Power Technologies (Albuquerque, New Mexico); The Curators of the University of Missouri (Columbia, Missouri); The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | William Ray Cravey (Albuquerque, New Mexico); Randy D. Curry (Columbia, Missouri); Kenneth Fox McDonald (Columbia, Missouri); Glenn A. Anderson (St. Charles, Missouri) |
| ABSTRACT | Method and apparatus for switching high power at high repetition rates. The apparatus is preferably a switch utilizing a pressurized flowing dielectric. The pressurized dielectric suppresses growth of dielectric breakdown byproducts, such as large bubbles and breakdown contamination, enabling lower dielectric flow rates to remove the byproducts. In addition to the advantage of lower flow rates, and thus smaller and lighter pumping means, the switch can switch high energies (up to megajoules) at fast repetition rates, up to thousands of pulses per second. |
| FILED | Thursday, June 17, 2004 |
| APPL NO | 10/870381 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Circuit makers and breakers 2/81.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312557 | Rastegar et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Omnitek Partners LLC (Bayshore, New York) |
| INVENTOR(S) | Jahangir S. Rastegar (Stony Brook, New York); David Haarhoff (Adelaide, Australia) |
| ABSTRACT | An apparatus for generating an electrical power upon an acceleration of the apparatus is provided. The apparatus including: a piezoelectric member having at least a portion thereof formed of a piezoelectric material; and a mass-spring unit having a spring element attached to the piezoelectric material and configured to compress and/or elongate within a predetermined limit, the mass-spring unit further having a mass offset from the piezoelectric material; wherein the mass-spring unit is configured to vibrate within the predetermined limit, upon the acceleration of the apparatus, the vibration applying a cyclic force to the piezoelectric member to generate an output power from the piezoelectric member. |
| FILED | Wednesday, April 27, 2005 |
| APPL NO | 11/116093 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/339 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312674 | Duwel et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Amy Duwel (Cambridge, Massachusetts); Luke Hohreiter (West Palm Beach, Florida); Joung-Mo Kang (Belmont, Massachusetts); Douglas W. White (Lexington, Massachusetts); David J. Carter (Maynard, Massachusetts); Mathew Varghese (Arlington, Massachusetts) |
| ABSTRACT | A resonator system wherein a plurality of resonators each including piezoelectric material are suspended relative to a substrate. An edge of each resonator is mechanically coupled to an edge of another resonator and the plurality of resonators expand and contract reaching resonance in response to an applied electric field. |
| FILED | Tuesday, September 21, 2004 |
| APPL NO | 10/946541 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/186 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312855 | Hintz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert T. Hintz (Ridgecrest, California); Rudolf G. Buser (Wall, New Jersey) |
| ABSTRACT | A long range eye-safe laser radar (LADAR) system for use in an environment where real-time non-cooperative identification of an object is required. In particular, a laser beam is aimed at an object, the laser energy reflected from the object is collected by a detector array for use in generating a composite of both a high resolution 3-Dimensional (3D) shape of the object and the object's high resolution micro-Doppler vibration spectrum, a characteristic of the object as unique as a fingerprint. The composite is then used to automatically identify the object by comparison to a database of similar composite sets of 3D shape and vibration spectrum information with the results of the identification conveyed to the user. |
| FILED | Thursday, October 26, 2006 |
| APPL NO | 11/591666 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optics: Measuring and testing 356/4.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312870 | Fritz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Bernard S. Fritz (Eagan, Minnesota); Aravind Padmanabhan (Plymouth, Minnesota); Peter Reutiman (Crystal, Minnesota) |
| ABSTRACT | An optical alignment detection system for detecting the alignment of a first object relative to a second object is provided. One or more light sources and one or more light detectors, either or both of which are secured relative to the second object, are used to detect the position of one or more light scattering elements on the first object. |
| FILED | Monday, October 31, 2005 |
| APPL NO | 11/263333 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/399 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313012 | Chuang et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ching-Te Chuang (South Salem, New York); Jae-Joon Kim (Yorktown Heights, New York); Keunwoo Kim (Somers, New York) |
| ABSTRACT | Techniques are provided for back-gate control in an asymmetrical memory cell. In one aspect, the cell includes five transistors and can be employed for static random access memory (SRAM) applications. An inventive memory circuit can include a plurality of bit line structures, a plurality of word line structures that intersect the plurality of bit line structures to form a plurality of cell locations, and a plurality of cells located at the plurality of cell locations. Each cell can be selectively coupled to a corresponding one of the bit line structures under control of a corresponding one of the word line structures. Each cell can include a first inverter having first and second field effect transistors (FETS) and a second inverter with third and fourth FETS that is cross-coupled to the first inverter to form a storage flip-flop. One of the FETS in the first inverter can be configured with independent front and back gates and can function as both an access transistor and part of one of the inverters. |
| FILED | Monday, February 27, 2006 |
| APPL NO | 11/362613 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313053 | Wodnicki |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Robert Gideon Wodnicki (Niskayuna, New York) |
| ABSTRACT | A scanning architecture that makes it possible to update only those ultrasonic transducer subelements of a mosaic transducer array that change from view to view. The configuration of the switch matrix is fully programmable. The switch matrix includes access switches that connect subelements to bus lines and matrix switches that connect subelements to subelements. Each subelement has a unit switch cell associated therewith, each unit switch cell comprising at least one access switch, at least one matrix switch, and addressing and control logic. Optionally, each unit switch cell also includes latches for storing the future switch states of the switches to be programmed. The switches themselves have memory for storing their current switch states. |
| FILED | Friday, October 29, 2004 |
| APPL NO | 10/978012 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313199 | Gupta et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hypres, Inc. (Elmsford, New York) |
| INVENTOR(S) | Deepnarayan Gupta (Hawthorne, New York); Oleg A. Mukhanov (Putnam Valley, New York) |
| ABSTRACT | A system for linearizing the output of a high power amplifier (HPA) designed to transmit an RF modulated signal includes in its transmit section a digital up-converter for processing baseband input signals and generating a desired digital RF waveform, T(s). The desired digital RF waveform T(s) is then fed to a digital predistorter circuit for producing a predistorted digital RF waveform P(s)T(s) which, as modified, may be applied via a high sampling speed high linearity digital to analog converter to the high power amplifier (HPA) to produce an output signal which is a linear function of the baseband input signal. The digital predistorter circuit may be of the adaptive type or of the predictive type. Circuits embodying the invention may include encoding circuitry for converting multi-bit signals to a serial stream of single-bit pulses for enabling simplification in the digital to analog conversion. In accordance with the invention, corrections for non-linearity of the HPA may be made directly on the RF waveform using ultra-high speed superconducting electronics (SCE) and decreasing the time delay between sensing a transmitted signal and generating a correcting (linearizing) signal. |
| FILED | Monday, February 03, 2003 |
| APPL NO | 10/357130 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/297 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313250 | Moskowitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ira S. Moskowitz (Washington, District of Columbia); Farid Ahmed (College Park, Maryland) |
| ABSTRACT | The present invention is a digital watermarking technique Phasemark™ for image authentication. Using a signature extracted from the original image, the present invention hides an encoded version of the signature back into the original image, forming the watermarked image. The hiding is done in the frequency domain. Specifically, the present invention is a new transform domain digital watermarking technique that hides a signature obtained from the Fourier phases into the magnitude spectrum of the same host image. The detection process computes the discrete Fourier transform of the watermarked image, extracts and decodes the embedded signature, and then correlates it with calculated phase information. Correlation metrics determine the degree of authenticity of the image. |
| FILED | Wednesday, March 31, 2004 |
| APPL NO | 10/817404 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313259 | Alyassin et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Abdalmajeid M. Alyassin (Niskayuna, New York); Ajay Kapur (Clifton Park, New York) |
| ABSTRACT | A method for multi-modality registration using virtual cursors including receiving a two-dimensional image dataset for an object at a first position and receiving a three-dimensional image dataset for the object at the first position. The three-dimensional image dataset includes a plurality of image slices. The two-dimensional image dataset is registered with the three-dimensional image dataset without taking into account a magnification factor. A user cursor position for a location in the two-dimensional image dataset is received. A slice of interest in the three-dimensional image dataset is received. The slice of interest is selected from the plurality of image slices in the three-dimensional image dataset. A shadow cursor position for a location in the three dimensional dataset is calculated. The shadow cursor position corresponds to the user cursor position and the calculating includes a correction for the magnification factor corresponding to the shadow cursor position for the slice of interest. The shadow cursor position is output. |
| FILED | Wednesday, November 26, 2003 |
| APPL NO | 10/722640 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313312 | Kimball et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Corning Incorporated (Corning, New York) |
| INVENTOR(S) | Ronald L. Kimball (Corning, New York); Robert A Knowlton (Wellsboro, Pennsylvania); Joseph E McCarthy (Addison, New York); Ji Wang (Painted Post, New York); Donnell T. Walton (Painted Post, New York); Luis A. Zenteno (Painted Post, New York) |
| ABSTRACT | According to one example of the invention an optical fiber comprises: (i) silica based, rare earth doped core having a first index of refraction n1; (ii) at least one silica based cladding surrounding the core and having a second index of refraction n2, such that n1>n2; wherein at least one of the core or cladding is doped with Al2O3, such that the ratio of max wt % to min wt % of Al2O3 concentration is less than 2:1. |
| FILED | Friday, February 11, 2005 |
| APPL NO | 11/056870 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07311009 | Kotovsky |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jack Kotovsky (Oakland, California) |
| ABSTRACT | A microelectromechanical systems stress sensor comprising a microelectromechanical systems silicon body. A recess is formed in the silicon body. A silicon element extends into the recess. The silicon element has limited freedom of movement within the recess. An electrical circuit in the silicon element includes a piezoresistor material that allows for sensing changes in resistance that is proportional to bending of the silicon element. |
| FILED | Wednesday, June 01, 2005 |
| APPL NO | 11/143543 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/777 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311011 | Clark et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Don T. Clark (Idaho Falls, Idaho); Richard L. Jones (Idaho Falls, Idaho); Terry D. Turner (Idaho Falls, Idaho); Joel M. Hubbell (Idaho Falls, Idaho); James B. Sisson (Idaho Falls, Idaho) |
| ABSTRACT | An access casing assembly structured for placement at least partially within a subterranean formation by forcing the access casing assembly thereinto, comprising a plurality of casing sections operably coupled to form a central elongated cavity for providing access to the subterranean region is disclosed. Further, a tip portion of the access casing assembly may include a porous filter through which liquid or gas may communicate with the central elongated cavity. Also, a receiving member or at least one engagement hub may form a portion of the central elongated cavity and may include an engagement feature configured for selectively and lockingly engaging a locking structure of a device to be positioned within the access casing assembly. Methods of use are disclosed. A tensiometer is disclosed including a chamber structured for allowing at least partially filling with a fluid subsequent to contact therewith. |
| FILED | Monday, November 22, 2004 |
| APPL NO | 10/995799 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/864.740 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311013 | Hoskinson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Reed L. Hoskinson (Rigby, Idaho); Kevin L. Kenney (Idaho Falls, Idaho); Ben C. Perrenoud (Rigby, Idaho) |
| ABSTRACT | A complex pendulum system biomass sensor having a plurality of pendulums. The plurality of pendulums allow the system to detect a biomass height and density. Each pendulum has an angular deflection sensor and a deflector at a unique height. The pendulums are passed through the biomass and readings from the angular deflection sensors are fed into a control system. The control system determines whether adjustment of machine settings is appropriate and either displays an output to the operator, or adjusts automatically adjusts the machine settings, such as the speed, at which the pendulums are passed through the biomass. In an alternate embodiment, an entanglement sensor is also passed through the biomass to determine the amount of biomass entanglement. This measure of entanglement is also fed into the control system. |
| FILED | Friday, September 29, 2006 |
| APPL NO | 11/537007 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/865.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311216 | Donnelly et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Aerobox Composites Structures, LLC (Rio Rancho, New Mexico) |
| INVENTOR(S) | Mathew William Donnelly (Edgewood, New Mexico); William Andrew Kasoff (Albuquerque, New Mexico); Patrick Carl Mcculloch (Irvine, California); Frederick Truman Williams (Albuquerque, New Mexico) |
| ABSTRACT | An improved, load bearing, modular design container structure assembled from thermoformed FRTP sandwich panels in which is utilized the unique core-skin edge configuration of the present invention in consideration of improved load bearing performance, improved useful load volume, reduced manufacturing costs, structural weight savings, impact and damage tolerance and repair and replace issues. |
| FILED | Thursday, July 24, 2003 |
| APPL NO | 10/428805 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Receptacles 220/1.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311680 | Lenhart et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Suzanne M. Lenhart (Knoxville, Tennessee); Vladimir A. Protopopescu (Knoxville, Tennessee); Eunok Jung (Seoul, South Korea) |
| ABSTRACT | A method for determining a chest pressure profile for cardiopulmonary resuscitation (CPR) includes the steps of representing a hemodynamic circulation model based on a plurality of difference equations for a patient, applying an optimal control (OC) algorithm to the circulation model, and determining a chest pressure profile. The chest pressure profile defines a timing pattern of externally applied pressure to a chest of the patient to maximize blood flow through the patient. A CPR device includes a chest compressor, a controller communicably connected to the chest compressor, and a computer communicably connected to the controller. The computer determines the chest pressure profile by applying an OC algorithm to a hemodynamic circulation model based on the plurality of difference equations. |
| FILED | Wednesday, September 29, 2004 |
| APPL NO | 10/953217 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery: Kinesitherapy 61/41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311755 | Carolan |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Air Products and Chemicals, Inc. (Allentown, Pennsylvania) |
| INVENTOR(S) | Michael Francis Carolan (Allentown, Pennsylvania) |
| ABSTRACT | Method of operating an oxygen-permeable mixed conducting membrane having an oxidant feed side and a permeate side, which method comprises controlling the differential strain between the oxidant feed side and the permeate side by varying either or both of the oxygen partial pressure and the total gas pressure on either or both of the oxidant feed side and the permeate side of the membrane while changing the temperature of the membrane from a first temperature to a second temperature. |
| FILED | Friday, September 17, 2004 |
| APPL NO | 10/943574 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas separation: Processes 095/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311774 | Alivisatos et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | A. Paul Alivisatos (Oakland, California); Eric C. Sher (Menlo Park, California); Liberato Manna (Berkeley, California) |
| ABSTRACT | Shaped nanocrystal particles and methods for making shaped nanocrystal particles are disclosed. One embodiment includes a method for forming a branched, nanocrystal particle. It includes (a) forming a core having a first crystal structure in a solution, (b) forming a first arm extending from the core having a second crystal structure in the solution, and (c) forming a second arm extending from the core having the second crystal structure in the solution. |
| FILED | Tuesday, November 02, 2004 |
| APPL NO | 10/980472 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/68 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311813 | Reyneke et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ineos USA LLC (Lisle, Illinois) |
| INVENTOR(S) | Rian Reyneke (Katy, Texas); Michael Foral (Aurora, Illinois); Christos G. Papadopoulos (Naperville, Illinois); Jeffrey S. Logsdon (Naperville, Illinois); Wayne W. Y. Eng (League City, Texas); Guang-Chung Lee (Houston, Texas); Ian Sinclair (Warrington, United Kingdom) |
| ABSTRACT | This invention is an improved distillation sequence for the separation and purification of ethylene from a cracked gas. A hydrocarbon feed enters a C2 distributor column. The top of the C2 distributor column is thermally coupled to an ethylene distributor column, and the bottoms liquid of a C2 distributor column feeds a deethanizer column. The C2 distributor column utilizes a conventional reboiler. The top of the ethylene distributor is thermally coupled with a demethanizer column, and the bottoms liquid of the ethylene distributor feeds a C2 splitter column. The ethylene distributor column utilizes a conventional reboiler. The deethanizer and C2 splitter columns are also thermally coupled and operated at a substantially lower pressure than the C2 distributor column, the ethylene distributor column, and the demethanizer column. Alternatively, a hydrocarbon feed enters a deethanizer column. The top of the deethanizer is thermally coupled to an ethylene distributor column, and the ethylene distributor column utilizes a conventional reboiler. The top of the ethylene distributor column is thermally coupled with a demethanizer column, and the bottoms liquid of the ethylene distributor column feeds a C2 splitter column. The C2 splitter column operates at a pressure substantially lower than the ethylene distributor column, the demethanizer column, and the deethanizer column. |
| FILED | Thursday, March 20, 2003 |
| APPL NO | 10/393460 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Mineral oils: Processes and products 28/102 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311859 | Loureiro et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Sergio Paulo Martins Loureiro (Saratoga Springs, New York); Anant Achyut Setlur (Niskayuna, New York); Darryl Stephen Williams (Clifton Park, New York); Mohan Manoharan (Niskayuna, New York); Alok Mani Srivastava (Niskayuna, New York) |
| ABSTRACT | Some embodiments of the present invention are directed toward nanocrystalline oxide-based phosphor materials, and methods for making same. Typically, such methods comprise a steric entrapment route for converting precursors into such phosphor material. In some embodiments, the nanocrystalline oxide-based phosphor materials are quantum splitting phosphors. In some or other embodiments, such nanocrystalline oxide based phosphor materials provide reduced scattering, leading to greater efficiency, when used in lighting applications. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/991980 |
| ART UNIT | 1755 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compositions 252/301.4R0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311882 | Renzi |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia National Laboratories (Livermore, California) |
| INVENTOR(S) | Ronald F. Renzi (Tracy, California) |
| ABSTRACT | A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i) a manifold comprising one or more channels extending therethrough wherein each channel is at least partially threaded, (ii) one or more threaded ferrules each defining a bore extending therethrough with each ferrule supporting a fluid conduit wherein each ferrule is threaded into a channel of the manifold, (iii) a substrate having one or more ports on its upper surface wherein the substrate is positioned below the manifold so that the one or more ports is aligned with the one or more channels of the manifold, and (iv) means for applying an axial compressive force to the substrate to couple the one or more ports of the substrate to a corresponding proximal end of a fluid conduit. |
| FILED | Friday, January 24, 2003 |
| APPL NO | 10/350541 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311926 | Grate et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jay W. Grate (West Richland, Washington); Jungbae Kim (Seoul, South Korea) |
| ABSTRACT | A particle (and a composition that includes a plurality of the particles) that includes at least one polypeptide molecule and at least one polymer covalently bound to the polypeptide molecule so as to form a polymer shell substantially encompassing the polypeptide molecule, wherein the particle does not define a dimension greater than about 1 μm. One example for making the particle includes modifying the polypeptide molecule to provide α, β-ethylenically unsaturated terminal functional groups, mixing the modified polypeptide molecule with a silicon-containing polymerizable compound, and subjecting the resulting mixture to conditions sufficient for polymerizing the polymerizable compound to form the particle. |
| FILED | Friday, December 20, 2002 |
| APPL NO | 10/326201 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/491 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311944 | Sambasivan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Applied Thin Films, Inc. (Evanston, Illinois) |
| INVENTOR(S) | Sankar Sambasivan (Chicago, Illinois); Kimberly A. Steiner (Chicago, Illinois); Krishnaswamy K. Rangan (Evanston, Illinois) |
| ABSTRACT | Aluminophosphate compounds and compositions as can be used for substrate or composite films and coating to provide or enhance, without limitation, planarization, anti-biofouling and/or anti-microbial properties. |
| FILED | Tuesday, December 23, 2003 |
| APPL NO | 10/745955 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312171 | Wagh et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Arun S. Wagh (Orland Park, Illinois); Allison L. Antink (Bolingbrook, Illinois) |
| ABSTRACT | A structural material of a polystyrene base and the reaction product of the polystyrene base and a solid phosphate ceramic. The ceramic is applied as a slurry which includes one or more of a metal oxide or a metal hydroxide with a source of phosphate to produce a phosphate ceramic and a poly (acrylic acid or acrylate) or combinations or salts thereof and polystyrene or MgO applied to the polystyrene base and allowed to cure so that the dried aqueous slurry chemically bonds to the polystyrene base. A method is also disclosed of applying the slurry to the polystyrene base. |
| FILED | Monday, August 15, 2005 |
| APPL NO | 11/204332 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Compositions: Ceramic 51/111 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312175 | Wertsching et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Alan K. Wertsching (Idaho Falls, Idaho); Eric S. Peterson (Idaho Falls, Idaho); John E. Wey (Idaho Falls, Idaho) |
| ABSTRACT | The invention includes an ion affinity material having an organic component which is sulfonated and which is chemically bonded to an inorganic substrate component. The invention includes a method of forming a metal binding material. A solid support material comprising surface oxide groups is provided and an organic component having at least one alkyl halide is covalently linked to at least some of the surface oxide groups to form a modified support material. The at least one alkyl halide is subsequently converted into an alkyl sulfonate. The invention further includes a method and system for extracting ions from a liquid. An ion exchange material having a sulfonated alkyl silane component covalently bonded to a metal oxide support material is provided and a liquid is exposed to the ion exchange material. |
| FILED | Wednesday, August 18, 2004 |
| APPL NO | 10/920932 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/401 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312461 | Lewellen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne LLC (Chicago, Illinois) |
| INVENTOR(S) | John W. Lewellen (Plainfield, Illinois); John Noonan (Naperville, Illinois) |
| ABSTRACT | A laparoscopic tumor therapy method and an articulated electron beam transport system are provided for use with a high power, long focus electron source for tumor therapy. The high power, long focus electron source generates an e-beam. The e-beam is transported through a laparoscopic tube proximate a target tumor for electron irradiation therapy. |
| FILED | Thursday, June 02, 2005 |
| APPL NO | 11/143837 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/396.ML0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312875 | Hanson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Gregory R. Hanson (Clinton, Tennessee); Philip R. Bingham (Knoxville, Tennessee); John T. Simpson (Knoxville, Tennessee); Thomas P. Karnowski (Knoxville, Tennessee); Edgar Voelkl (Austin, Texas) |
| ABSTRACT | Systems and methods are described for obtaining two-wavelength differential-phase holograms. A method includes determining a difference between a filtered analyzed recorded first spatially heterodyne hologram phase and a filtered analyzed recorded second spatially-heterodyned hologram phase. |
| FILED | Wednesday, April 23, 2003 |
| APPL NO | 10/421444 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/484 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313226 | Falce et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Calabazas Creek Research, Inc. (San Mateo, California) |
| INVENTOR(S) | Louis R. Falce (Surprise, Arizona); R. Lawrence Ives (Saratoga, California) |
| ABSTRACT | A plurality of high atomic number wires are sintered together to form a porous rod that is parted into porous disks which will be used as x-ray targets. A thermally conductive material is introduced into the pores of the rod, and when a stream of electrons impinges on the sintered wire target and generates x-rays, the heat generated by the impinging x-rays is removed by the thermally conductive material interspersed in the pores of the wires. |
| FILED | Wednesday, September 14, 2005 |
| APPL NO | 11/226659 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313499 | Battiste |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Richard L. Battiste (Oak Ridge, Tennessee) |
| ABSTRACT | Methods and apparatus are described for characterizing the temporal-spatial properties of a dynamic fluid front within a mold space while the mold space is being filled with fluid. A method includes providing a mold defining a mold space and having one or more openings into the mold space; heating a plurality of temperature sensors that extend into the mold space; injecting a fluid into the mold space through the openings, the fluid experiencing a dynamic fluid front while filling the mold space with the fluid; and characterizing temporal-spatial properties of the dynamic fluid front by monitoring a temperature of each of the plurality of heated temperature sensors while the mold space is being filled with the fluid. An apparatus includes a mold defining a mold space; one or more openings for introducing a fluid into the mold space and filling the mold space with the fluid, the fluid experiencing a dynamic fluid front while filling the mold space; a plurality of heated temperature sensors extending into the mold space; and a computer coupled to the plurality of heated temperature sensors for characterizing the temporal-spatial properties of the dynamic fluid front. |
| FILED | Tuesday, January 03, 2006 |
| APPL NO | 11/324764 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313582 | Bhanot et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Gyan Bhanot (Princeton, New Jersey); Matthias A. Blumrich (Ridgefield, Connecticut); Dong Chen (Croton On Hudson, New York); Alan G. Gara (Mount Kisco, New York); Mark E. Giampapa (Irvington, New York); Philip Heidelberger (Cortlandt Manor, New York); Burkhard D. Steinmacher-Burow (Mount Kisco, New York); Pavlos M. Vranas (Bedford Hills, New York) |
| ABSTRACT | Methods and systems for performing arithmetic functions. In accordance with a first aspect of the invention, methods and apparatus are provided, working in conjunction of software algorithms and hardware implementation of class network routing, to achieve a very significant reduction in the time required for global arithmetic operation on the torus. Therefore, it leads to greater scalability of applications running on large parallel machines. The invention involves three steps in improving the efficiency and accuracy of global operations: (1) Ensuring, when necessary, that all the nodes do the global operation on the data in the same order and so obtain a unique answer, independent of roundoff error; (2) Using the topology of the torus to minimize the number of hops and the bidirectional capabilities of the network to reduce the number of time steps in the data transfer operation to an absolute minimum; and (3) Using class function routing to reduce latency in the data transfer. With the method of this invention, every single element is injected into the network only once and it will be stored and forwarded without any further software overhead. In accordance with a second aspect of the invention, methods and systems are provided to efficiently implement global arithmetic operations on a network that supports the global combining operations. The latency of doing such global operations are greatly reduced by using these methods. |
| FILED | Monday, February 25, 2002 |
| APPL NO | 10/468991 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/490 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07311723 | Seibel et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Eric J. Seibel (Seattle, Washington); Thomas A. Reh (Seattle, Washington); Blake Miller (Seattle, Washington) |
| ABSTRACT | In one aspect, the invention provides vision prosthesis systems. Exemplary vision prosthesis systems of the invention comprise a light energy generator operably connected to a wearable head piece comprising a device for directing light energy produced by the light energy generator onto a mammalian retina, wherein the light energy generator is tuned to emit light energy of sufficient power to modulate neural activity in the retina. In another aspect, the invention provides methods for irradiating neurons in the retina of the mammalian eye by directing light energy produced by a light energy generator onto a mammalian retina. The methods of the invention may be used to directly modulate the activity of retinal neurons or to introduce molecules into retinal cells. |
| FILED | Friday, July 09, 2004 |
| APPL NO | 10/888428 |
| ART UNIT | 3739 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07311962 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yoel Fink (Cambridge, Massachusetts); Shandon Hart (Cambridge, Massachusetts); Garry Maskaly (North Quincy, Massachusetts); Burak Temelkuran (Boston, Massachusetts) |
| ABSTRACT | A mirror structure includes a plurality of features of a defined size. The features include alternating spatial units of a chalcogenide glass and a thermoplastic polymer, and are specifically arranged in an ordered form so that the structure is highly reflective. Thermally-assisted methods are introduced for forming such structures. |
| FILED | Tuesday, July 16, 2002 |
| APPL NO | 10/196403 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312059 | Loeb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Lawrence A. Loeb (Bellevue, Washington); Leroy Hood (Seattle, Washington); Motoshi Suzuki (Nogoya, Japan) |
| ABSTRACT | The present invention provides a method for identifying a thermostable polymerase having altered fidelity. The method consists of generating a random population of polymerase mutants by mutating at least one amino acid residue of a thermostable polymerase and screening the population for one or more active polymerase mutants by genetic selection. For example, the invention provides a method for identifying a thermostable polymerase having altered fidelity by mutating at least one amino acid residue in an active site O-helix of a thermostable polymerase. The invention also provides thermostable polymerases and nucleic acids encoding thermostable polymerases having altered fidelity, for example, high fidelity polymerases and low fidelity polymerases. The invention additionally provides a method for identifying one or more mutations in a gene by amplifying the gene with a high fidelity polymerase. The invention further provides a method for accurately copying repetitive nucleotide sequences using a high fidelity polymerase mutant. The invention also provides a method for diagnosing a genetic disease using a high fidelity polymerase mutant. The invention further provides a method for randomly mutagenizing a gene by amplifying the gene using a low fidelity polymerase mutant. |
| FILED | Thursday, March 31, 2005 |
| APPL NO | 11/096645 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312088 | Farquharson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Real-Time Analyzers, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Stuart Farquharson (Meriden, Connecticut) |
| ABSTRACT | Apparatus for use in effecting surface-enhanced Raman spectroscopy comprises first and second containment means, the first containment means containing a known quantity of a reference chemical having an effective surface-enhanced Raman factor, and the second containment means containing a surface-enhanced Raman-active medium and being sufficiently transparent, at least at one optical access location, to permit both the excitation irradiation of, and also the collection of surface-enhanced Raman scattered radiation from, a common field of view of the surface-enhanced Raman-active medium. The apparatus is constructed for carrying out the method of the invention; i.e., for effecting intimate mixing, substantially prior to introduction to the surface-enhanced Raman-active medium contained in the second containment means, of the reference chemical with an analyte chemical-containing solution introduced through an entrance into the first containment means. The homogeneous test solution so formed permeates the SER-active material in the second containment means, which is irradiated at the common field of view so as to produce SER scattered radiation for collection and quantitative analysis. |
| FILED | Thursday, July 29, 2004 |
| APPL NO | 10/902511 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07312174 — Method for preparing highly loaded, highly dispersed platinum metal on a carbon substrate
| US 07312174 | Regalbuto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Chicago, Illinois) |
| INVENTOR(S) | John R. Regalbuto (Glenview, Illinois); Xianghong Hao (Chicago, Illinois) |
| ABSTRACT | The invention is directed to a simple method for preparing highly dispersed, highly loaded platinum metal elements on various carbon substrates, including conductive carbon black, which is utilized in fuel cell electrodes. Utilizing carbon with a controlled point of zero charge (PZC) and maintaining a desired pH value throughout the adsorption of metal onto the carbon substrate, a high metal loading is achieved for a given surface area of the carbon substrate. |
| FILED | Monday, September 08, 2003 |
| APPL NO | 10/657649 |
| ART UNIT | 1755 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/185 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312378 | Hannah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | L. Curtis Hannah (Gainesville, Florida); Thomas W. Greene (Zionsville, Indiana) |
| ABSTRACT | The subject invention pertains to novel mutant polynucleotide molecules that encode enzymes that have increased heat stability. These polynucleotides, when expressed in plants, result in increased yield in plants grown under conditions of heat stress. The polynucleotide molecules of the subject invention encode maize endosperm ADP glucose pyrophosphorylase (AGP) and soluble starch synthase (SSS) enzyme activities. Plants and plant tissue bred to contain, or transformed with, the mutant polynucleotides, and expressing the polypeptides encoded by the polynucleotides, are also contemplated by the present invention. The subject invention also concerns methods for isolating polynucleotides and polypeptides contemplated within the scope of the invention. Methods for increasing yield in plants grown under conditions of heat stress are also provided. |
| FILED | Wednesday, October 20, 2004 |
| APPL NO | 10/970230 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/298 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313194 | Bar-Ness et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Yeheskel Bar-Ness (Marlboro, New Jersey); Songping Wu (Sunnyvale, California) |
| ABSTRACT | A phase noise mitigation method which mitigates phase noise for MIMO-OFDM. A criterion is provided which jointly optimizes both spectral efficiency and receiver performance by determining the best number of pilots. |
| FILED | Wednesday, October 20, 2004 |
| APPL NO | 10/969779 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/267 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07312041 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arbor Vita Corporation (Sunnyvale, California) |
| INVENTOR(S) | Peter S. Lu (Mountain View, California); Johannes Schweizer (Mountain View, California); Chamorro Somoza Diaz-Sarmiento (Palo Alto, California); Michael P. Belmares (San Jose, California) |
| ABSTRACT | The invention provides reagents and methods for detecting pathogen infections in human samples. This detection utilizes specific proteins to detect the presence of pathogen proteins or abnormal expression of human proteins resulting from pathogen infections. Specific methods, compositions and kits are disclosed herein for the detection of oncogenic Human papillomavirus E6 proteins in clinical samples. |
| FILED | Tuesday, July 29, 2003 |
| APPL NO | 10/630590 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312076 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Osel, Inc. (Santa Clara, California) |
| INVENTOR(S) | Chia-Hwa Chang (Mountain View, California); David A. Simpson (Redwood City, California); Theresa Li-Yun Chang (Los Gatos, California); Qiang Xu (Cupertino, California); John A. Lewicki (Los Gatos, California) |
| ABSTRACT | The present invention relates to Lactobacillus species recombinantly altered to express a biologically active protein. The invention also related to methods of providing the bacteria to the vagina. |
| FILED | Friday, January 05, 2007 |
| APPL NO | 11/620588 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312228 | Cushman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mark S. Cushman (West Lafayette, Indiana); Yves G. Pommier (Bethesda, Maryland) |
| ABSTRACT | The synthesis and biological activity of benzoisoindoloisoquinolone compounds are described. The synthesis and biological activity of C-11-substituted indenoisoquinolones are also described. Indenoisoquinolones substituted at C-11 are prepared by McMurry reactions of 11-ketoindenoisoquinolones with aldehydes. |
| FILED | Tuesday, May 11, 2004 |
| APPL NO | 10/553532 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07312080 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | W. Allen Miller (Ames, Iowa); Bryony C. Bonning (Ames, Iowa) |
| ABSTRACT | The invention involves combining a peptide toxin effective against insects, including but not limited to thrips, leaf hoppers, and beetles, with a transport peptide capable of facilitating transfer of the peptide toxin from the gut of an insect to the hemocoel. The combination can be effected by a fusion of genetic material encoding the peptide toxin and the transport peptide, such that expression of the genetic material fusion results in synthesis of a fusion protein combining the functions of both the toxin and the transport protein. Ingestion of the fusion protein by the sucking insect transfers the fusion protein into the insect's gut from which it is transferred into the hemocoel due to the functional activity of the transport peptide where the toxin exerts its toxic effect upon the insect. In a preferred embodiment, the invention is effective in control of such sucking insects as aphids, whiteflies and the like, and other vectors that transmit viruses in a circulative manner. |
| FILED | Wednesday, January 15, 2003 |
| APPL NO | 10/346144 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07312088 | Farquharson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Real-Time Analyzers, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Stuart Farquharson (Meriden, Connecticut) |
| ABSTRACT | Apparatus for use in effecting surface-enhanced Raman spectroscopy comprises first and second containment means, the first containment means containing a known quantity of a reference chemical having an effective surface-enhanced Raman factor, and the second containment means containing a surface-enhanced Raman-active medium and being sufficiently transparent, at least at one optical access location, to permit both the excitation irradiation of, and also the collection of surface-enhanced Raman scattered radiation from, a common field of view of the surface-enhanced Raman-active medium. The apparatus is constructed for carrying out the method of the invention; i.e., for effecting intimate mixing, substantially prior to introduction to the surface-enhanced Raman-active medium contained in the second containment means, of the reference chemical with an analyte chemical-containing solution introduced through an entrance into the first containment means. The homogeneous test solution so formed permeates the SER-active material in the second containment means, which is irradiated at the common field of view so as to produce SER scattered radiation for collection and quantitative analysis. |
| FILED | Thursday, July 29, 2004 |
| APPL NO | 10/902511 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07312713 | Alfano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Robert R. Alfano (Bronx, New York); Wubao Wang (Flushing, New York); Henry Sztul (New York, New York); Yury Budansky (Oakland, New Jersey) |
| ABSTRACT | A system for detecting ice formation on metal, painted metal and other material surfaces can include a transparent window having an exterior surface upon which ice can form; a light source and optics configured and arranged to illuminate the exterior surface of the window from behind the exterior surface; and a detector and optics configured and arranged to receive light backscattered by the exterior surface and any ice disposed on the exterior surface and determine the thickness of the ice layer. For example, the system can be used with aircraft by placing one or more windows in the wings of the aircraft. The system is used for a novel optical method for real-time on-board detection and warning of ice formation on surfaces of airplanes, unmanned aerial vehicles (UAVs), and other vehicles and stationary structures to improve their safety and operation. |
| FILED | Thursday, December 15, 2005 |
| APPL NO | 11/303190 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/583 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07313475 | Green |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| INVENTOR(S) | Steven M. Green (Cupertino, California) |
| ABSTRACT | A method and associated system for time delay banking for aircraft arrival time, aircraft departure time and/or en route flight position. The delay credit value for a given flight may decrease with passage of time and may be transferred to or traded with other flights having the same or a different user (airline owner or operator). The delay credit value for a given aircraft flight depends upon an initial delay credit value, which is determined by a central system and depends upon one or more other flight characteristics. Optionally, the delay credit value decreases with passage of time. Optionally, a transaction cost is assessed against a delay credit value that is used on behalf of another flight with the same user or is traded with a different user. |
| FILED | Tuesday, February 01, 2005 |
| APPL NO | 11/053713 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07312469 | Ong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
| INVENTOR(S) | Beng S. Ong (Mississauga, Canada); Ping Liu (Mississauga, Canada); Maria Birau (Mississauga, Canada); Yiliang Wu (Mississauga, Canada) |
| ABSTRACT | An electronic device comprising a semiconductor layer in contact with a number of electrodes, wherein the semiconductor layer includes a small molecular thiophene compound consisting of a plurality of thiophene units, each thiophene unit being represented by structure (A) wherein each thiophene unit is bonded at either or both of the second ring position and the fifth ring position, wherein there is at least one thiophene unit where R1 is present at the third ring position or the fourth ring position, or at both the third ring position and the fourth ring position, wherein for any two adjacent thiophene units there is excluded the simultaneous presence of the same or different R1 at the 3-position of one thiophene unit and at the 3′-position of the other thiophene unit. |
| FILED | Thursday, June 10, 2004 |
| APPL NO | 10/865445 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 07311839 | Schulze-Makuch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | New Mexico Tech Research Foundation (Socorro, New Mexico); The Texas A and M University System (College Station, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Dirk Schulze-Makuch (El Paso, Texas); Robert S. Bowman (Lemitar, New Mexico); Suresh Pillai (College Station, Texas) |
| ABSTRACT | Systems and methods are described for removing biological pathogens using surfactant-modified zeolite (SMZ). A method for removing biological pathogens from a fluid or a fluid-based gel includes filtering the fluid or fluid-based gel using SMZs. A method for removing air-borne biological pathogens includes drawing air through a fluid layer or a fluid-based gel layer and filtering the fluid or the fluid-based gel layer using SMZs. |
| FILED | Friday, May 02, 2003 |
| APPL NO | 10/429222 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/660 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07313367 | Bialek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | Edward J. Bialek (Buffalo, New York); James J. Heimbueger (Buffalo, New York); Christopher J. Irwin (Buffalo, New York) |
| ABSTRACT | Provided is a switched multiplexer configured to combine first, second, third and fourth signal paths each covering a sub-octave in a frequency range of from about 2 to about 18 GHz and to remove transmitter harmonics of an input signal to create a stable output impedance across the frequency range. The switched multiplexer comprises a transmit switch, a first diplexer and a power combiner. The first diplexer is connected in parallel with a second diplexer. The first diplexer comprises first and second signal paths. The second diplexer comprises third and fourth signal paths. Each one of the first, second and third signal paths include respective ones of the first switch, a second switch and a third switch, each interconnected to respective ones of a first signal path high-pass filter, second signal path low-pass filter and third signal path low-pass filter by respective ones of a first, second and third filter. Each one of the first, second and third filters have a respective filter capability in the range of from about 6-10.4 GHz, 2-3.5 GHz, and 3.5-6 GHz. |
| FILED | Monday, March 14, 2005 |
| APPL NO | 11/079796 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/63.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 25, 2007.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2007/fedinvent-patents-20071225.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page