FedInvent™ Patents
Patent Details for Tuesday, February 12, 2008
This page was updated on Monday, March 27, 2023 at 12:55 AM GMT
Department of Defense (DOD)
US 07328461 | Lewis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Morning Pride Manufacturing, L.L.C. (Dayton, Ohio) |
INVENTOR(S) | Patricia K. Lewis (Tipp City, Ohio); William L. Grilliot (Dayton, Ohio); Mary I. Grilliot (Dayton, Ohio) |
ABSTRACT | In a pair of protective trousers having a fly, in which a flap extending from a first edge of a torso-covering portion covers a second edge thereof in a closed condition of the fly but not in an opened condition of the fly and in which the first and second edges are secured releasably to each other, as by a hook-and-loop fastener, in the closed condition, a gusset extends along and between the first and second edges, in the opened and closed conditions. |
FILED | Thursday, February 24, 2005 |
APPL NO | 11/067201 |
ART UNIT | 3765 — SELECT * FROM codes_techcenter; |
CURRENT CPC | Apparel 02/234 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07328580 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Ching-Pang Lee (Cincinnati, Ohio); Steven Robert Brassfield (Cincinnati, Ohio); Ronald Scott Bunker (Niskayuna, New York) |
ABSTRACT | A wall in a gas turbine engine includes inner and outer surfaces having a row of compound chevron film cooling holes extending therethrough. The chevron holes diverge both longitudinally and laterally between an inlet at the wall inner surface and a chevron outlet at the wall outer surface. |
FILED | Wednesday, June 23, 2004 |
APPL NO | 10/874900 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Power plants 060/752 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07328879 | Plangetis |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Gus F. Plangetis (Annapolis, Maryland) |
ABSTRACT | A bearing washer is inserted into a horizontally elongated recess formed within the top flat surface of an upper tapered wedge of a support assembly through which equipment is adjustably positioned on a foundation. The upper wedge is vertically and horizontally adjusted in slidingly positioned contact with a lower tapered wedge along inclined surfaces within a recess formed therein before attachment of the tapered wedges to each other by horizontal fastener bolts extending through the upper wedge and the lower wedge. In such adjusted position of the wedges, a convex surface on the inserted bearing washer is in contact with a concave surface within a recess formed in the top surface of the upper wedge to support the equipment in close spaced relationship thereabove. Slidable adjustment of the wedges is limited by a recess shoulder in the lower tapered wedge to avoid excessive loading of the fastener bolts under severe shock and vibration conditions imposed on the equipment positioned on the foundation. |
FILED | Friday, June 03, 2005 |
APPL NO | 11/147652 |
ART UNIT | 3632 — Static Structures, Supports and Furniture |
CURRENT CPC | Supports 248/679 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07328921 | Miciukiewicz |
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APPLICANT(S) | |
ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
INVENTOR(S) | Michael J. Miciukiewicz (Trumbull, Connecticut) |
ABSTRACT | A device which allows fluid to enter and/or exit the device axially or radially thru multiple ports, on and/or offset from the axis of rotation. One end of the assembly can be rotated axially with respect to the other while keeping fluids isolated from each other. Compared to existing multi-path fluid swivel joint designs, this approach is simple in construction, compact in size, and exhibits a relatively low pressure drop. |
FILED | Monday, April 04, 2005 |
APPL NO | 11/097194 |
ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Pipe joints or couplings 285/275 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329048 | Klusman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Steven Arlen Klusman (Indianapolis, Indiana); Mark Stephen Henry (Indianapolis, Indiana) |
ABSTRACT | A fluid damping system for damping a shaft within a gas turbine engine component. The fluid damping system including a damping liquid and a pressurized gas in a closed self contained system. In one aspect the damping liquid is cooled by being disposed in a heat transfer relationship with a fuel. |
FILED | Tuesday, July 19, 2005 |
APPL NO | 11/184682 |
ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
CURRENT CPC | Bearings 384/99 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329050 | Dugan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Translume, Inc. (Ann Arbor, Michigan) |
INVENTOR(S) | Mark A. Dugan (Ann Arbor, Michigan); Ali A. Said (Ann Arbor, Michigan); Philippe Bado (Ann Arbor, Michigan) |
ABSTRACT | Disclosed herein are an optical device, such as a connector or mode enlarger, and a method of fabricating the device. The disclosed device includes an optical medium having a first face for, e.g., permanent attachment to a waveguide, a second face for, e.g., a non-permanent connection, and a region between the first and second faces. A non-fiber, connector waveguide is disposed in the region to propagate the single-mode signal from the first face to the second face. The connector waveguide is optically matched to the waveguide at the first face to receive the single-mode signal carried by the waveguide. The connector waveguide includes a taper section such that the connector waveguide is enlarged at the second face to support an expanded beam of the single-mode signal for propagation through the non-permanent connection. In some cases, the taper section receives the single-mode signal from an input section of the connector waveguide to generate an expanded or narrowed beam of the single-mode signal via discrete modulation of waveguide cross-section. An output section of the connector waveguide then supports the propagation of the expanded or narrowed beam of the single-mode signal through the non-permanent connection. |
FILED | Friday, March 10, 2006 |
APPL NO | 11/372609 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical waveguides 385/55 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329101 | Carper et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Douglas Melton Carper (Trenton, Ohio); Suresh Subramanian (Mason, Ohio) |
ABSTRACT | The integral layer provides a ductile interface for attachment locations of a turbine engine component where a metallic surface is adjacent the attachment location. The ductile layer provides a favorable load distribution through the composite at the attachment location, and eliminates the need for a metallic shim. |
FILED | Wednesday, December 29, 2004 |
APPL NO | 11/025222 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Fluid reaction surfaces 416/219.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329323 | Dhawan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Anuj Dhawan (Raleigh, North Carolina); Tushar Kanti Ghosh (Raleigh, North Carolina); John Muth (Raleigh, North Carolina); Abdelfattah Seyam (Cary, North Carolina) |
ABSTRACT | Methods and systems for selectively connecting and disconnecting conductors in a fabric are disclosed. First and second conductors are integrated into a fabric such that the conductors intersect at a crossover point. The conductors are bonded to each other at the crossover point to improve AC and DC characteristics. Disconnect areas may be provided near the crossover point to allow selective disconnection of the conductors from the crossover point. |
FILED | Friday, November 19, 2004 |
APPL NO | 10/993452 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/73.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329377 | Ha et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Yung-Hoon Ha (Springfield, Virginia); Edwin L. Thomas (Natick, Massachusetts) |
ABSTRACT | Methods are provided for producing a shrunken replica or a shrunken inverse replica of a multicontinuous structure. In one embodiment, the method comprises (1) infiltrating a first multicontinuous structure with a first fluid material which can be immobilized and shrunken, wherein the first multicontinuous structure comprises at least a first phase and a second phase which is immiscible with the first phase, and the infiltration displaces the second phase in the first multicontinuous structure to form a second multicontinuous structure which comprises at least the first phase and a third phase which consists of the first fluid material; (2) immobilizing the infiltrated first fluid material in the second multicontinuous structure; (3) removing the first phase from the second multicontinuous structure; and (4) shrinking (e.g., by a pyrolysis process) the third phase of the second multicontinuous structure, to produce an isotropically shrunken inverse replica of the first multicontinuous structure. |
FILED | Friday, March 12, 2004 |
APPL NO | 10/799160 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/317 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329487 | Lee |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
INVENTOR(S) | Cheng-Chi Lee (Houston, Texas) |
ABSTRACT | The present invention provides a method of screening individuals at risk for developing diseases caused by trinucleotide repeat sequence instability. Specifically, the present invention is drawn to screening individuals at risk for developing autosomal dominant spinocerebellar ataxia type 6 by determining the length of a CAG trinucleotide repeat in the α1A calcium channel gene of the individual. In addition, there is provided a method of identifying genes which are disease-causing due to trinucleotide repeat sequence instability by large scale genotyping. |
FILED | Monday, May 12, 2003 |
APPL NO | 10/435804 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329503 | Ching et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Wei-Mei Ching (Bethesda, Maryland); Chien-Chung Chao (N. Bethesda, Maryland); Xuan Li (Silver Spring, Maryland); Hua-Wei Chen (Germantown, Maryland) |
ABSTRACT | The invention relates to a method for the detection of prior exposure to Coxiella. burnetii infection by antibody-based assays using recombinant, immunodominant C. burnetii polypeptides. The invention also relates to the design of biotin or His-tagged C. burnetii proteins useful in the antibody-based assays as standardized antigen reagents. |
FILED | Tuesday, April 04, 2006 |
APPL NO | 11/401013 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329545 | Pamula et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Vamsee K. Pamula (Durham, North Carolina); Michael G. Pollack (Durham, North Carolina); Philip Y. Paik (Durham, North Carolina); Hong Ren (Chapel Hill, North Carolina); Richard B. Fair (Durham, North Carolina) |
ABSTRACT | In a method for sampling a continuous liquid flow, the liquid flow is supplied to a surface along an input flow path. The liquid flow is sampled by forming a sample droplet from a portion of the liquid flow. The sample droplet is moved along an analysis flow path to a processing area of the surface, where the sample droplet is processed. Discrete sample droplets are formed and moved using an electrowetting technique. A binary mixing apparatus and method are also provided. The apparatus comprises an array of electrodes, an electronic controller communicating with the electrodes, a sample droplet supply area communicating with the array, and an additive droplet supply area communicating with the array. The electronic controller alternately energizes and de-energizes selected electrodes to carry out droplet-to-droplet binary mixing operations to obtain one or more droplets having a target mixing ratio. |
FILED | Tuesday, September 24, 2002 |
APPL NO | 10/253342 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/53 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329649 | Fisher et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Paul B. Fisher (Scarsdale, New York); Zao-Zhong Su (New York, New York) |
ABSTRACT | The present invention relates to methods and compositions for inhibiting proliferation and inducing cell death in a population of cancer cells by (i) increasing the amount of the differentiation associated protein MDA-7, and (ii) decreasing RAS activity within the population. It is based, at least in part, on the discovery that decreasing expression of a mutated, activated K-ras gene, together with introducing an expressible mda-7 gene, in pancreatic cells had a synergistic growth-inhibitory and anti-survival effect, and abolished tumorigenicity of the cells in athymic nude mice. The methods of the invention may be directed to the therapy of pancreatic cancer and other malignancies. |
FILED | Friday, February 20, 2004 |
APPL NO | 10/783571 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329727 | Deming |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Timothy J. Deming (Summerland, California) |
ABSTRACT | Methods and compositions for the generation of polypeptides having varied material properties are disclosed herein. Methods include means for initiating the polymerization of aminoacid-N-carboxyanhydride (NCA) monomer by combining the monomer with an amido-containing metallacycle, for making self assembling amphiphilic block copolypeptides and related protocols for adding oligo(ethyleneglycol) functionalized aminoacid-N-carboxyanhydrides (NCAs) to polyaminoacid chains. Additional methods include means of adding an end group to the carboxy terminus of a polyaminoacid chain by reacting an alloc-protected amino acid amide with a transition metal-donor ligand complex to forming an amido-amidate metallacycle for use in further polymerization reactions. Novel compositions for use in peptide synthesis and design including five and six membered amido-containing metallacycles and block copolypeptides are also disclosed. |
FILED | Friday, November 14, 2003 |
APPL NO | 10/712967 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/333 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329895 | Cole et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Barrett E. Cole (Bloomington, Minnesota); Wei Yang (Minnetonka, Minnesota); Thomas E. Nohava (Apple Valley, Minnesota) |
ABSTRACT | A sensor comprises two photodiodes sensitive to different wavelengths. The photodiodes or detectors are stacked in a vertical relationship to each other. A bandpass filter is provided to limit the wavelengths of light reaching the detectors. The photodiodes are formed of various combinations of materials such as AlGaN or InGaN, or different compositions of the same material. Charge detectors are coupled to each detector to provide a signal representative of the amount of radiation detected in their corresponding bandwidths. A biological sample is provided proximate the filter. A laser is used to illuminate the biological sample to create biofluorescence corresponding to intrinsic tryptophan of bacteria. |
FILED | Friday, February 22, 2002 |
APPL NO | 10/081369 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330032 | Donnangelo |
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APPLICANT(S) | |
ASSIGNEE(S) | The Mitre Corporation (McLean, Virginia) |
INVENTOR(S) | Nicholas C. Donnangelo (Purcellville, Virginia) |
ABSTRACT | Techniques for imaging a search region to detect a dielectric target include placing multiple electrodes outside the search region. At least two electrodes are activated independently of each other. Emitter circuits are connected to corresponding emitter electrodes. Each emitter circuit is configured for using its emitter electrode to produce an electric field with wavelength longer than about one hundred meters. Receiver circuits are connected to corresponding receiver electrodes. Each receiver circuit is configured for using its receiver electrode to measure a property of an electric field produced, at least in part, by an emitter electrode. A processor determines a property of a dielectric target inside the search region based on measurements from the receiver circuits using a subset of the emitter circuits. Among other uses, these techniques allow humans to be detected inside building-size regions, even when hidden by visually opaque blocking material of small dielectric constant. |
FILED | Monday, November 22, 2004 |
APPL NO | 10/993421 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/452 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330090 | Itoh et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Tatsuo Itoh (Rolling Hills, California); Atsushi Sanada (Yamaguchi, Japan); Christophe Caloz (Quebec, Canada) |
ABSTRACT | A high frequency resonator circuit and method of fabrication is described which has a resonant frequency independent of physical resonator dimensions. The resonator operates in a zeroeth-order mode on a composite right/left-handed (CRLH) transmission line (TL). The LH wave properties of the CRLH-TL contributing anti-parallel phase and group velocities. In one variation, the unit cells are formed from microstrip techniques, preferably creating alternating interdigitated capacitors and stub inductors. The resonant wavelength of the resonator is dependent on the electrical characteristics of the unit cells and not the physical size of the resonator in relation to the desired resonant wavelength. The resonator is created with at least 1.5 unit cells and the Q of the resonator is substantially independent of the number of unit cells utilized. The resonator circuit is particularly well suited for reducing resonator size, and allows resonators of various wavelengths to be fabricated within a fixed board area. |
FILED | Monday, March 28, 2005 |
APPL NO | 11/092143 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Wave transmission lines and networks 333/219 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330149 | Weatherford |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Shaun David Weatherford (Camarillo, California) |
ABSTRACT | A monopulse radar tracking method which analyzes boresight error information provided a monopulse radar to determine a location for two targets. The monopulse radar tracking method analyzes the boresight error information to determine an angle of arrival for a dominant target and a secondary target. |
FILED | Thursday, February 09, 2006 |
APPL NO | 11/357455 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/149 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330507 | Levasseur et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey K. Levasseur (Owens Cross Roads, Alabama); Brent A. Worley (Madison, Alabama) |
ABSTRACT | A communication system with a multi-channel array antenna utilizes a receiver matching process that adapts the pass band frequency response of each channel to a selected reference channel. This process is implemented digitally by inserting a tapped delay line filter in each channel, selecting one of the channels as a reference, and adapting the others to match the reference in both phase and amplitude. The process is performed for each system calibration cycle, which occurs just before receive data is captured and processed. The improvements include an apparatus and an algorithm that select a reference channel in the adaptive process during each system calibration cycle, producing optimal, or near optimal, channel matching. |
FILED | Tuesday, February 03, 2004 |
APPL NO | 10/774647 |
ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Pulse or digital communications 375/232 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330530 | Chapman |
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APPLICANT(S) | |
ASSIGNEE(S) | Illinois Institute of Technology (Chicago, Illinois) |
INVENTOR(S) | Leroy Dean Chapman (Saskatoon, Canada) |
ABSTRACT | A method for detecting an enhanced image of an object by independently analyzing, detecting, digitizing, and combining images acquired on a high and a low angle side of a rocking curve of a crystal analyzer. An x-ray beam generated by a line x-ray source is collimated by a crystal monochromator including two non-matching crystals to form an x-ray area beam. The x-ray area beam is transmitted through an object to be imaged and onto an image detector and the image is digitized. The digitized images are simultaneously solved, preferably on a pixel-by-pixel basis, to derive an enhanced image which has dramatically improved contrast and spatial resolution over an image acquired through conventional radiology methods. |
FILED | Monday, October 04, 2004 |
APPL NO | 10/957884 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/85 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330550 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Shikik T. Johnson (State College, Pennsylvania); Stephen D. Russell (San Diego, California) |
ABSTRACT | A cryptographic system includes: a) a light source for generating an excitation light signal; b) a spatial light modulator for encoding the excitation light signal with data; c) a wavelength dispersive element for transforming the excitation light signal into a spectral encoded light signal characterized by relative peak intensities at specific wavelengths; d) an optical detector for generating an information output signal in response to receiving an optical input signal, wherein the information output signal represents spectral and intensity characteristics of the optical input signal; and e) a processor for validating the information output signal if differences between representations of the optical input signal, and representations of the spectral encoded light signal are within predetermined limits. |
FILED | Wednesday, February 19, 2003 |
APPL NO | 10/371544 |
ART UNIT | 2137 — Memory Access and Control |
CURRENT CPC | Cryptography 380/256 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330565 | Der |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Sandor Zoltan Der (Alexandria, Virginia) |
ABSTRACT | An algorithm for the detection of military vehicles in FLIR imagery is used as a prescreener to eliminate large areas of the image from further analysis. The output is a list of likely target locations with confidence numbers, which may be sent to a more complex clutter rejection algorithm for analysis. The algorithm uses simple features, and is intended to be applicable to a wide variety of target-sensor geometries, sensor configurations, and applications. |
FILED | Tuesday, February 25, 2003 |
APPL NO | 10/372340 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330653 | Roberts et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Mark W. Roberts (San Diego, California); Markham E. Lasher (La Jolla, California) |
ABSTRACT | A Quantum Dense Coding System. The system includes a source, a transmitter and a receiver. The source is capable of down-converting a pump photon into a signal photon and an idler photon and outputting probability amplitudes, the signal photon and the idler photon, wherein the signal photon and the idler photon have an equal probability of outputting to a transmission channel and a reception channel. The transmitter is capable of receiving probability amplitudes, signal photons and idler photons from the transmission channel; and selectively changing vertical and horizontal phases of probability amplitudes of signal photons and idler photons; and outputting probability amplitudes, signal photons and idler photons. The receiver is capable of receiving probability amplitudes, signal photons and idler photons from the reception channel and the transmitter; and identifying vertical and horizontal phase changes created by the transmitter. A method for the system is also described. |
FILED | Monday, November 15, 2004 |
APPL NO | 10/989139 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Optical communications 398/40 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330736 | Redi |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | Jason Keith Redi (Belmont, Massachusetts) |
ABSTRACT | The invention relates to communications devices for reduced energy communications in an ad hoc network. The communication device includes a first low powered transceiver for initiating communications with other communications devices and a second transceiver for transmitting data messages to the other communications devices once communication is initiated. The communication device also includes a communications control processor for determining times at which the other communications devices will be available to receive communications based on scheduling data received from those communication devices. |
FILED | Thursday, March 10, 2005 |
APPL NO | 11/078257 |
ART UNIT | 2617 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Telecommunications 455/553.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330795 | Roukes et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Michael L. Roukes (Pasadena, California); Scott E. Fraser (La Canada, California); Jerry E. Solomon (Glendale, California) |
ABSTRACT | An outputs signal, v(t), is generated from a bioNEMs transducer and mixed with a reference signal and then filtered to generate a correlator output, r(t). The correlator output is detected to generate a signal u(t) and then determined whether the signal u(t) satisfies a predetermined threshold. If qualified, it is then decided whether the signal u(t) represents a predetermined type of interaction between a free ligand in a fluid in which the NEMS device is immersed and a receptor attached to the transducer. The threshold is the Neyman-Pearson criterion based on a predetermined probability of false detection, Pfa. The interaction may be binding of a free ligand to the receptor or releasing a bound ligand from the receptor by competitive binding with the free ligand. The step of detecting comprises detecting the envelope of the signal, r(t). |
FILED | Wednesday, May 07, 2003 |
APPL NO | 10/502466 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330840 | Straatveit |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Sverre Nils Straatveit (White Plains, Maryland) |
ABSTRACT | An apparatus including a genetic processor receiving a plurality of genomes, each genome of the first plurality of genomes including at least one of a device, a method, and an article of manufacture, wherein each genome comprises at least one gene, each gene comprising at least one allele; and a fuzzy logic scorer communicating with the genetic processor to score the plurality of genomes using fuzzy logic-based fitness criteria thereby obtaining a genomic score for each genome of the plurality of genomes and an average generational score. The genetic processor eliminates any genome of the plurality of genomes that has a score below a level to provide a remaining plurality of genomes and generates another plurality of genomes by mating the remaining plurality of genomes using a genetic algorithm. Optionally, the apparatus further includes a mutation generator communicating with the genetic processor and at least one of eliminating the gene in the remaining plurality of genomes; introducing at least one of a new gene and a new allele to characterize each genome of the remaining plurality of genomes; and wherein the at least one gene comprises at least one of an active gene and an inactive gene one of inactivating the active gene and activating the inactive gene of the at least one gene in at least one mutated genome of the remaining plurality of genomes. |
FILED | Tuesday, March 07, 2006 |
APPL NO | 11/369060 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Artificial intelligence 76/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330849 | Gerasoulis et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | IAC Search and Media, Inc. (Oakland, California) |
INVENTOR(S) | Apostolos Gerasoulis (Highland Park, New Jersey); Wei Wang (Edison, New Jersey); Hyun-Ju Seo (Somerset, New Jersey) |
ABSTRACT | Techniques to assign a ranking value to objects in a database such as a collection of cross referencing documents, the World-Wide Web or a hyperlinked database are described. The ranking value assigned to a given data object represents a cross-cluster strength metric and is a function of the object's importance across all groups or clusters in which the object is classified. The cross-cluster strength metric may be particularly beneficial in enhancing the performance of web-based search engines because it emphasizes the importance of objects that appear in multiple groups while de-emphasizing the importance of objects that, while highly linked within one or a few groups, are relatively unlinked to objects in other groups. |
FILED | Thursday, October 13, 2005 |
APPL NO | 11/250341 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 07329225 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Stephen W. Smith (Durham, North Carolina); Matthew Fronheiser (Bally, Pennsylvania); Rebecca Booi (Ann Arbor, Michigan); Patrick D. Wolf (Durham, North Carolina) |
ABSTRACT | An oscillating shaft is scanned to provide images including the oscillating shaft in vivo in real-time with a real-time three-dimensional (3D) ultrasound scanner. An interventional device can be guided in vivo using an ultrasound scanner and includes a sheath having a bore therethrough from a proximal portion to a spaced-apart distal portion. A shaft has a proximal portion and a spaced-apart distal portion and is configured for insertion into the bore of the sheath. A vibrator is coupled to the proximal portion of the shaft and is configured to cause the distal portion of the shaft to oscillate at a shaft frequency. An isolator is coupled to the proximal portion of the sheath and to the vibrator, wherein the isolator is configured to reduce damping of an oscillation of the shaft by the sheath. |
FILED | Thursday, February 12, 2004 |
APPL NO | 10/777441 |
ART UNIT | 3768 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Surgery 6/443 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329406 | Brooks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Peter C. Brooks (Carmel, New York); David A. Cheresh (Encinitas, California) |
ABSTRACT | The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing αvβ3 antagonists. |
FILED | Thursday, July 15, 2004 |
APPL NO | 10/892653 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/152.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329485 | Zlotnick |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Adam Zlotnick (Norman, Oklahoma) |
ABSTRACT | Methods of identifying a compound that inhibit, enhance and/or misdirect assembly of a viral capsid include providing fluorescently-labeled capsid polypeptides labeled with a fluorescent dye that changes fluorescence at high concentration, wherein assembly of the capsid polypeptides into the viral capsid results in juxtaposition of at least one of the N-terminus and C-terminus of the capsid polypeptides. In vitro assembly reactions are performed utilizing the labeled capsid polypeptide in the presence of the at least one test compound, and an amount of fluorescence is detected at at least one time point following induction of assembly, wherein the induction of assembly is detected as a change in the fluorescence of the sample. It is then determined whether the change in fluorescence detected in the presence of the at least one test compound following induction of assembly is decreased, increased, or occurs at a fast rate when compared to the fluorescence detected in the absence of the at least one test compound, wherein such decrease is an indication that the at least one test compound interferes with assembly of the viral capsid. |
FILED | Thursday, October 12, 2006 |
APPL NO | 11/546796 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329495 | Chen et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
INVENTOR(S) | Lei L. Chen (Pearland, Texas); Marsha L. Frazier (Houston, Texas) |
ABSTRACT | The present invention relates to methods and compositions concerning resistance to a drug for cancer comprising aberrant KIT signal, such as aberrant KIT sequence or expression. In a specific embodiment, the cancer is also initially responsive to imatinib therapy, such as in gastrointestinal stromal tumors (GISTs). In particular embodiments, a mutation in a KIT polynucleotide confers resistance to imatinib treatment, and in specific embodiments the exemplary mutation is at 1982T→C. Thus, the invention provides a means to adjust for or circumvent the resistance to imatinib drug treatment. |
FILED | Thursday, June 09, 2005 |
APPL NO | 11/148770 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329502 | Staudt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Louis M. Staudt (Silver Spring, Maryland); Andreas Rosenwald (Bethesda, Maryland); Wyndham Wilson (Washington, District of Columbia); Todd S. Barry (Seattle, Washington); Adrian Wiestner (Bethesda, Maryland) |
ABSTRACT | It has been surprisingly found that ZAP-70 expression, both at the protein and mRNA levels, is indicative of clinical subgroups of CLL/SLL patients. In particular, high ZAP-70 expression is indicative of Ig-unmutated CLL/SLL. Methods are provided for discriminating between clinical subgroups of CLL/SLL, by determining whether subjects overexpress ZAP-70 mRNA mRNA or protein. |
FILED | Tuesday, December 03, 2002 |
APPL NO | 10/309548 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329511 | Tobin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Allan J. Tobin (Los Angeles, California); Mark G. Erlander (Tarzana, California); Daniel L. Kaufman (Santa Monica, California) |
ABSTRACT | The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD65 which encode at least one epitope for autoantibodies to GAD65. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD65. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD65. In another embodiment, the invention provides for the detection of autoantibodies to GAD65 using the GAD65 polypeptides coded for by the cDNA molecules of the invention. |
FILED | Friday, August 15, 2003 |
APPL NO | 10/641149 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329536 | Zeng et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Oakland University (Rochester, Michigan); Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Xiangqun Zeng (Rochester, Michigan); Gabrielle Stryker (Rochester Hills, Michigan); Raymond L. Mernaugh (Franklin, Tennessee) |
ABSTRACT | An apparatus comprising one or more piezoelectric mass sensors for use in diagnostic and analytic processes, in particular for immunochemical detection of diagnostically relevant analytes in real time, is described. Each piezoelectric mass sensor comprises a piezoelectric crystal with a receptor surface which has immobilized thereon a lawn of recombinant antibodies comprising single VH chain or single-chain Fv (scFv) polypeptides specific for a particular antigen. Binding of antigen to the recombinant antibodies results in a change in mass on the receptor surface which is detected as a change in resonant frequency. In a preferred embodiment, the receptor layer is a precious metal such as gold which facilitates self-assembly of the recombinant antibodies into a lawn on the receptor surface via a cysteine residue at the carboxy terminus of the attachment polypeptide. |
FILED | Friday, June 04, 2004 |
APPL NO | 10/861617 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329541 | Barbas |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Carlos F. Barbas (Solana Beach, California) |
ABSTRACT | Zinc finger-nucleotide binding polypeptides having binding specificity for target nucleotides containing one or GNN triplets are provided. Compositions containing such polypeptides and the use of such polypeptides and compositions for regulating gene expression are also provided. |
FILED | Friday, February 10, 2006 |
APPL NO | 11/351561 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329543 | Stamler et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Jonathan S. Stamler (Chapel Hill, North Carolina); Joseph Bonaventura (Beaufort, North Carolina); John R. Pawloski (Raleigh, North Carolina); Timothy J. McMahon (Durham, North Carolina) |
ABSTRACT | Red blood cells can be loaded with low molecular weight nitrosylating agents, such as S-nitrosothiols, to act as a delivery system for NO+ groups to tissues. Loaded red blood cells can be used in methods of therapy for conditions which are characterized by abnormal O2 metabolism of tissues, oxygen-related toxicity, abnormal vascular tone, abnormal red blood cell adhesion, or abnormal O2 delivery by red blood cells. Such treatment of red blood cells can be extended to in vivo therapies, with the object to achieve an increase in the ratio of red blood cell S-nitrosothiol to hemoglobin. |
FILED | Tuesday, July 12, 2005 |
APPL NO | 11/179349 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/372 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329638 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Victor C. Yang (Ann Arbor, Michigan); Yoon Jeong Park (Seoul, South Korea); Junfeng Liang (Westfield, New Jersey) |
ABSTRACT | The present invention relates to multicomponent compositions and methods of administering these compositions, which specifically translocate therapeutic molecules (e.g., drugs or prodrugs) across biological membranes thus reducing potential toxic side effects on nontargeted cells and tissues. |
FILED | Thursday, April 29, 2004 |
APPL NO | 10/835151 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329641 | Fronticelli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Clara Fronticelli (Timonium, Maryland); William S. Brinigar (Yardley, Pennsylvania) |
ABSTRACT | The functional characteristics of heme proteins can be modified to produce hemoglobins that can be used as blood substitutes in different therapeutic applications. Stable polymers of tetrameric hemoglobin, and of myoglobin molecules, are provided for use in the blood substitutes. |
FILED | Monday, November 01, 2004 |
APPL NO | 10/979483 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329643 | Tracey et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Feinstein Institute for Medical Research (Manhasset, New York) |
INVENTOR(S) | Kevin J. Tracey (Old Greenwich, Connecticut); Haicho Wang (Edison, New Jersey); Andrew E. Sama (Manhasset, New York) |
ABSTRACT | Methods of inhibiting HMGB1 release by a mammalian cell are provided. The methods comprise treating the cell with sufficient fetuin to inhibit HMGB1 release. Methods of inhibiting an inflammatory cytokine cascade in a mammal are also provided. These methods comprise administering sufficient fetuin to the mammal to inhibit HMGB1 release in the mammal. Also provided are methods of treating a condition in a mammal characterized by an inflammatory cytokine cascade. These methods comprise administering sufficient fetuin to the mammal to inhibit HMGB1 release in the mammal. |
FILED | Friday, May 13, 2005 |
APPL NO | 11/129672 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329649 | Fisher et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Paul B. Fisher (Scarsdale, New York); Zao-Zhong Su (New York, New York) |
ABSTRACT | The present invention relates to methods and compositions for inhibiting proliferation and inducing cell death in a population of cancer cells by (i) increasing the amount of the differentiation associated protein MDA-7, and (ii) decreasing RAS activity within the population. It is based, at least in part, on the discovery that decreasing expression of a mutated, activated K-ras gene, together with introducing an expressible mda-7 gene, in pancreatic cells had a synergistic growth-inhibitory and anti-survival effect, and abolished tumorigenicity of the cells in athymic nude mice. The methods of the invention may be directed to the therapy of pancreatic cancer and other malignancies. |
FILED | Friday, February 20, 2004 |
APPL NO | 10/783571 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329669 | Zhu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Neurocrine Biosciences, Inc. (San Diego, California) |
INVENTOR(S) | Yun-Fei Zhu (San Diego, California); Collin Regan (San Diego, California); Jaimie K Rueter (San Diego, California); Zhiqiang Guo (San Diego, California); Yongsheng Chen (San Diego, California); Charles Q Huang (San Diego, California) |
ABSTRACT | GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7 and X are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof. |
FILED | Friday, June 02, 2006 |
APPL NO | 11/446583 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/274 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329728 | Barbas, III et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); Novartis AG (Basel, Switzerland) |
INVENTOR(S) | Carlos F. Barbas, III (Del Mar, California); Michael Joseph Kadan (Adams Town, Maryland); Roger Beerli (San Diego, California) |
ABSTRACT | Fusion proteins for use as ligand-dependent transcriptional regulators are provided. The fusion proteins include a nucleotide binding domain operatively linked to a ligand-binding domain. They also can include a transcription regulating domain. The nucleotide binding domain is a zinc-finger peptide that binds to a targeted contiguous nucleotide sequence of from 3 to about 18 nucleotides are provided. The fusion proteins are used for gene therapy. Also provided are polynucleotides encoding the fusion proteins, expression vectors, and transfected cells. |
FILED | Friday, June 02, 2000 |
APPL NO | 09/586625 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329735 | Tsien et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Robert E. Campbell (San Diego, California); Geoffrey S. Baird (San Diego, California) |
ABSTRACT | The present invention relates generally to variant fluorescent proteins, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. The invention also relates to methods of making and using such fluorescent protein monomers and dimers. |
FILED | Tuesday, January 17, 2006 |
APPL NO | 11/334218 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329744 | Morris et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | St. Jude Children's Research Hospital Inc. (Memphis, Tennessee); The Hospital for Sick Children (, Canada) |
INVENTOR(S) | Stephan W. Morris (Memphis, Tennessee); Zhigui Ma (Memphis, Tennessee); Johann K. Hitzler (Toronto, Canada) |
ABSTRACT | The invention relates to human nucleotide sequences which occur as a result of the t(1;22)(p13;q13) chromosomal translocation event which is known to occur almost invariable in young children with acute megakaryoblastic leukemia. The translocation results in the formation of fusion genes which encode fusion proteins. The invention provides the nucleotide sequences of transcripts of the fusion genes and the amino acid sequences of the fusion proteins encoded thereby. Also provided are methods for detecting the t(1, 22) translocation, for identifying agents capable of binding to the fusion protein and for identifying agents useful for treating patients with acute megakaryoblastic leukemia. |
FILED | Tuesday, April 23, 2002 |
APPL NO | 10/475917 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329758 | Grubbs et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Robert H. Grubbs (South Pasadena, California); Matthias Scholl (Arcadia, California) |
ABSTRACT | The present invention relates to novel metathesis catalysts with an imidazolidine-based ligand and to methods for making and using the same. The inventive catalysts are of the formula wherein: M is ruthenium or osmium; X and X1 are each independently an anionic ligand; L is a neutral electron donor ligand; and, R, R1 R6, R7, R8, and R9 are each independently hydrogen or a substituent selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl, aryl, C1-C20 carboxylate, C1-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthiol, aryl thiol, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl, the substituent optionally substituted with one or more moieties selected from the group consisting of C1-C10 alkyl, C1-C10 alkoxy, aryl, and a functional group selected from the group consisting of hydroxyl, thiol, thioether, ketone, aldehyde, ester, ether, amine, imine, amide, nitro, carboxylic acid, disulfide, carbonate, isocyanate, carbodiimide, carboalkoxy, carbamate, and halogen. The inclusion of an imidazolidine ligand to the previously described ruthenium or osmium catalysts has been found to dramatically improve the properties of these complexes. The inventive catalysts maintains the functional group tolerance of previously described ruthenium complexes while having enhanced metathesis activity that compares favorably to prior art tungsten and molybdenum systems. |
FILED | Monday, May 22, 2000 |
APPL NO | 09/576370 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 548/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329769 | Smith, III |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Milton R. Smith, III (East Lansing, Michigan) |
ABSTRACT | A process for producing a ring-substituted arene borane which comprises reacting a ring-substituted arene with an HB organic compound in the presence of a catalytically effective amount of an iridium or rhodium complex with three or more substituents, excluding hydrogen, bonded to the iridium or rhodium and a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium, to form the ring-substituted arene borane. Also provided are catalytic compounds for catalyzing the process comprising an iridium or rhodium complex with three or substituents, excluding hydrogen, bonded to the iridium or rhodium and optionally, a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium. |
FILED | Tuesday, March 29, 2005 |
APPL NO | 11/092076 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 558/287 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329775 | Appella et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Daniel H. Appella (Rockville, Maryland); Michael C. Myers (Evanston, Illinois) |
ABSTRACT | Ketoamine compounds and related methods for reactivation of tumor suppressor protein p53. |
FILED | Monday, November 01, 2004 |
APPL NO | 10/978702 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 560/250 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329874 | Shah |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Radiation Monitoring Devices, Inc. (Watertown, Massachusetts) |
INVENTOR(S) | Kanai S. Shah (Newton, Massachusetts) |
ABSTRACT | The present invention includes very fast scintillator materials including lutetium iodide doped with Cerium (Lu1-xI3:Cex; LuI3:Ce). The LuI3 scintillator material has surprisingly good characteristics including high light output, high gamma-ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma-ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration. |
FILED | Thursday, November 10, 2005 |
APPL NO | 11/271053 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/363.30 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330576 | Raman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Raghav Raman (Cupertino, California); Bhargav Raman (San Jose, California); Sandy A. Napel (Menlo Park, California); Geoffrey D. Rubin (Woodside, California) |
ABSTRACT | A method that allows the quantification of the true mass of a calcium fragment located along a vessel is provided. The method is independent of the level of arterial contrast enhancement, does not require protocol-specific or scanner-specific calibration scans, and allows a detailed analysis of calcium distribution patterns. For each identified calcium fragment, the average intensity and volume is determined as a function of a plurality of intensity thresholds. Using these determined values brightness volume products are calculated for each of the plurality of intensity thresholds. The mass of a calcium segment is subsequently obtained from the calculated brightness volume products extrapolated at zero intensity and reference calcium parameters. The mass and volume of the calcium fragments could be visualized with respect to a vessel in a computer display. |
FILED | Thursday, December 02, 2004 |
APPL NO | 11/003937 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330602 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Jin Hung Lee (Menlo Park, California); Brad Osgood (Stanford, California); Dwight G. Nishimura (Palo Alto, California) |
ABSTRACT | An optimal sampling pattern for variable density sampling of a continuous signal uses a statistical knowledge of the signal to determine an autocorrelation matrix from which a basis set is identified. Sampling is performed at locations determined from an eigenvector matrix, and the sampled output provides coefficients for the basis set. The reconstructed signal output is a summation of the multiplication of the coefficients and the basis set. |
FILED | Friday, September 17, 2004 |
APPL NO | 10/944381 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/278 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330748 | Balaban et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Robert S. Balaban (Bethesda, Maryland); Kathleen M. Ward (Arlington, Virginia); Anthony H. Aletras (Rockville, Maryland) |
ABSTRACT | Method for determining in vivo concentration of a metabolite that includes administering a contrast agent to a subject, allowing the contrast agent to disperse to tissue of interest, performing CEDST MRI analysis of the subject, and comparing the results to known in vitro results to determine metabolite concentration. |
FILED | Friday, September 24, 2004 |
APPL NO | 10/948942 |
ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/420 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07328534 | Dinwoodie |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | SunPower Corporation, Systems (San Jose, California) |
INVENTOR(S) | Thomas L. Dinwoodie (Piedmont, California) |
ABSTRACT | A barrier, such as a PV module, is secured to a base by a support to create a shingle assembly with a venting region defined between the barrier and base for temperature regulation. Water resistant junctions may be formed between the bases of adjacent shingle assemblies of an array of shingle assemblies. The base may include an insulation layer underlying a water barrier. The base may also include a waterproofing element; the width and height of the barrier may be shorter than the width and height of the waterproofing element. |
FILED | Wednesday, February 02, 2005 |
APPL NO | 11/049260 |
ART UNIT | 3637 — Static Structures, Supports and Furniture |
CURRENT CPC | Static structures 052/173.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07328629 | Farthing et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Gas Technology Institute (Des Plaines, Illinois) |
INVENTOR(S) | William Earl Farthing (Pinson, Alabama); Larry Gordon Felix (Pelham, Alabama); Todd Robert Snyder (Birmingham, Alabama) |
ABSTRACT | An apparatus and method for diluting and cooling that is extracted from high temperature and/or high pressure industrial processes. Through a feedback process, a specialized, CFD-modeled dilution cooler is employed along with real-time estimations of the point at which condensation will occur within the dilution cooler to define a level of dilution and diluted gas temperature that results in a gas that can be conveyed to standard gas analyzers that contains no condensed hydrocarbon compounds or condensed moisture. |
FILED | Friday, April 22, 2005 |
APPL NO | 11/112360 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/863.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329554 | Hanna et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Midwest Research Institute (Kansas City, Missouri) |
INVENTOR(S) | Mark Cooper Hanna (Boulder, Colorado); Robert Reedy (Golden, Colorado) |
ABSTRACT | A GaAlInP compound semiconductor and a method of producing a GaAlInP compound semiconductor are provided. The apparatus and method comprises a GaAs crystal substrate in a metal organic vapor deposition reactor. Al, Ga, In vapors are prepared by thermally decomposing organometallic compounds. P vapors are prepared by thermally decomposing phospine gas, group II vapors are prepared by thermally decomposing an organometallic group IIA or IIB compound. Group VIB vapors are prepared by thermally decomposing a gaseous compound of group VIB. The Al, Ga, In, P, group II, and group VIB vapors grow a GaAlInP crystal doped with group IIA or IIB and group VIB elements on the substrate wherein the group IIA or IIB and a group VIB vapors produced a codoped GaAlInP compound semiconductor with a group IIA or IIB element serving as a p-type dopant having low group II atomic diffusion. |
FILED | Thursday, November 08, 2001 |
APPL NO | 10/552102 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/46 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329608 | Babayan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Steven E. Babayan (Huntington Beach, California); Robert F. Hicks (Los Angeles, California) |
ABSTRACT | The invention is embodied in a plasma flow device or reactor having a housing that contains conductive electrodes with openings to allow gas to flow through or around them, where one or more of the electrodes are powered by an RF source and one or more are grounded, and a substrate or work piece is placed in the gas flow downstream of the electrodes, such that said substrate or work piece is substantially uniformly contacted across a large surface area with the reactive gases emanating therefrom. The invention is also embodied in a plasma flow device or reactor having a housing that contains conductive electrodes with openings to allow gas to flow through or around them, where one or more of the electrodes are powered by an RF source and one or more are grounded, and one of the grounded electrodes contains a means of mixing in other chemical precursors to combine with the plasma stream, and a substrate or work piece placed in the gas flow downstream of the electrodes, such that said substrate or work piece is contacted by the reactive gases emanating therefrom. In one embodiment, the plasma flow device removes organic materials from a substrate or work piece, and is a stripping or cleaning device. In another embodiment, the plasma flow device kills biological microorganisms on a substrate or work piece, and is a sterilization device. In another embodiment, the plasma flow device activates the surface of a substrate or work piece, and is a surface activation device. In another embodiment, the plasma flow device etches materials from a substrate or work piece, and is a plasma etcher. In another embodiment, the plasma flow device deposits thin films onto a substrate or work piece, and is a plasma-enhanced chemical vapor deposition device or reactor. |
FILED | Friday, November 05, 2004 |
APPL NO | 10/982120 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Semiconductor device manufacturing: Process 438/689 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329742 | Doyle et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Sharon A. Doyle (Walnut Creek, California); Michael B. Murphy (Severna Park, Maryland) |
ABSTRACT | The present method is an improved in vitro selection protocol that relies on magnetic separations for DNA aptamer production that is relatively easy and scalable without the need for expensive robotics. The ability of aptamers selected by this method to recognize and bind their target protein with high affinity and specificity, and detail their uses in a number of assays is also described. Specific TTF1 and His6 aptamers were selected using the method described, and shown to be useful for enzyme-linked assays, Western blots, and affinity purification. |
FILED | Friday, September 03, 2004 |
APPL NO | 10/934856 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329791 | Balachandran |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Uthamalingam Balachandran (Hinsdale, Illinois) |
ABSTRACT | A method of converting C2 and/or higher alkanes to olefins by contacting a feedstock containing C2 and/or higher alkanes with a first surface of a metal composite membrane of a sintered homogenous mixture of an Al oxide or stabilized or partially stabilized Zr oxide ceramic powder and a metal powder of one or more of Pd, Nb, V, Zr, Ta and/or alloys or mixtures thereof. The alkanes dehydrogenate to olefins by contact with the first surface with substantially only atomic hydrogen from the dehydrogenation of the alkanes passing through the metal composite membrane. Apparatus for effecting the conversion and separation is also disclosed. |
FILED | Wednesday, March 31, 2004 |
APPL NO | 10/814210 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemistry of hydrocarbon compounds 585/660 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329857 | Weiss |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Jonathan D. Weiss (Albuquerque, New Mexico) |
ABSTRACT | A side-emitting fiber optic position sensor and method of determining an unknown position of an object by using the sensor. In one embodiment, a concentrated beam of light source illuminates the side of a side-emitting fiber optic at an unknown axial position along the fiber's length. Some of this side-illuminated light is in-scattered into the fiber and captured. As the captured light is guided down the fiber, its intensity decreases due to loss from side-emission away from the fiber and from bulk absorption within the fiber. By measuring the intensity of light emitted from one (or both) ends of the fiber with a photodetector(s), the axial position of the light source is determined by comparing the photodetector's signal to a calibrated response curve, look-up table, or by using a mathematical model. Alternatively, the side-emitting fiber is illuminated at one end, while a photodetector measures the intensity of light emitted from the side of the fiber, at an unknown position. As the photodetector moves further away from the illuminated end, the detector's signal strength decreases due to loss from side-emission and/or bulk absorption. As before, the detector's signal is correlated to a unique position along the fiber. |
FILED | Friday, March 24, 2006 |
APPL NO | 11/389660 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Radiant energy 250/227.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329872 | Blackwood et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Larry G. Blackwood (Idaho Falls, Idaho); Andrew J. Edwards (Idaho Falls, Idaho); James K. Jewell (Idaho Falls, Idaho); Edward L. Reber (Idaho Falls, Idaho); Edward H. Seabury (Idaho Falls, Idaho) |
ABSTRACT | A method for detecting an element is described and which includes the steps of providing a gamma-ray spectrum which has a region of interest which corresponds with a small amount of an element to be detected; providing nonparametric assumptions about a shape of the gamma-ray spectrum in the region of interest, and which would indicate the presence of the element to be detected; and applying a statistical test to the shape of the gamma-ray spectrum based upon the nonparametric assumptions to detect the small amount of the element to be detected. |
FILED | Monday, September 19, 2005 |
APPL NO | 11/231141 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/358.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329874 | Shah |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Radiation Monitoring Devices, Inc. (Watertown, Massachusetts) |
INVENTOR(S) | Kanai S. Shah (Newton, Massachusetts) |
ABSTRACT | The present invention includes very fast scintillator materials including lutetium iodide doped with Cerium (Lu1-xI3:Cex; LuI3:Ce). The LuI3 scintillator material has surprisingly good characteristics including high light output, high gamma-ray stopping efficiency, fast response, low cost, good proportionality, and minimal afterglow that the material is useful for gamma-ray spectroscopy, medical imaging, nuclear and high energy physics research, diffraction, non-destructive testing, nuclear treaty verification and safeguards, and geological exploration. |
FILED | Thursday, November 10, 2005 |
APPL NO | 11/271053 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/363.30 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330397 | Ganesan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Schlumberger Technology Corporation (Sugar Land, Texas) |
INVENTOR(S) | Harini Ganesan (Sugar Land, Texas); Nataliya Mayzenberg (Missouri City, Texas) |
ABSTRACT | A mud-pulse telemetry tool includes a tool housing, a motor disposed in the tool housing, and a magnetic coupling coupled to the motor and having an inner shaft and an outer shaft. The tool may also include a stator coupled to the tool housing, a restrictor disposed proximate the stator and coupled to the magnetic coupling, so that the restrictor and the stator adapted to generate selected pulses in a drilling fluid when the restrictor is selectively rotated. The tool may also include a first anti-jam magnet coupled to the too housing, and an second anti-jam magnet disposed proximate the first anti-jam magnet and coupled to the inner shaft and/or the outer shaft, wherein at least one of the first anti-jam magnet and the second anti-jam magnet is an electromagnet, and wherein the first anti-jam magnet and the second anti-jam magnet are positioned with adjacent like poles. |
FILED | Thursday, January 27, 2005 |
APPL NO | 10/905953 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/83 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330533 | Sampayon |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Stephen E. Sampayon (Manteca, California) |
ABSTRACT | A compact, self-contained x-ray source, and a compact x-ray source panel having a plurality of such x-ray sources arranged in a preferably broad-area pixelized array. Each x-ray source includes an electron source for producing an electron beam, an x-ray conversion target, and a multilayer insulator separating the electron source and the x-ray conversion target from each other. The multi-layer insulator preferably has a cylindrical configuration with a plurality of alternating insulator and conductor layers surrounding an acceleration channel leading from the electron source to the x-ray conversion target. A power source is connected to each x-ray source of the array to produce an accelerating gradient between the electron source and x-ray conversion target in any one or more of the x-ray sources independent of other x-ray sources in the array, so as to accelerate an electron beam towards the x-ray conversion target. The multilayer insulator enables relatively short separation distances between the electron source and the x-ray conversion target so that a thin panel is possible for compactness. This is due to the ability of the plurality of alternating insulator and conductor layers of the multilayer insulators to resist surface flashover when sufficiently high acceleration energies necessary for x-ray generation are supplied by the power source to the x-ray sources. |
FILED | Thursday, May 05, 2005 |
APPL NO | 11/124550 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/119 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330996 | Coteus et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Paul W. Coteus (Yorktown Heights, New York); Alan G. Gara (Mount Kisco, New York); Mark E. Giampapa (Irvington, New York); Philip Heidelberger (Cortlandt Manor, New York); Burkhard D. Steinmacher-Burow (Mount Kisco, New York) |
ABSTRACT | A method for maintaining full performance of a file system in the presence of a failure is provided. The file system having N storage devices, where N is an integer greater than zero and N primary file servers where each file server is operatively connected to a corresponding storage device for accessing files therein. The file system further having a secondary file server operatively connected to at least one of the N storage devices. The method including: switching the connection of one of the N storage devices to the secondary file server upon a failure of one of the N primary file servers; and switching the connections of one or more of the remaining storage devices to a primary file server other than the failed file server as necessary so as to prevent a loss in performance and to provide each storage device with an operating file server. |
FILED | Monday, February 25, 2002 |
APPL NO | 10/468990 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07329517 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Paul Micah Johnson (Brighton, Michigan); Hsiuchin Yang (Decatur, Georgia); Charles D. Derby (Atlanta, Georgia); Phang C. Tai (Atlanta, Georgia) |
ABSTRACT | The present invention provides an isolated polypeptide (escapin), and fragments thereof, from the sea hare Aplysia californica that have antimicrobial action directed against fungi, yeast, bacteria, and cyanobacteria. Further, the present invention provides an isolated nucleic acid, and fragments thereof, that encode the polypeptide and fragments thereof. Also provided are primers for detecting the nucleic acids of the present invention. A method of inhibiting microbial growth and inhibiting biofilm formation on a surface is also provided. |
FILED | Wednesday, April 06, 2005 |
APPL NO | 11/100328 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329727 | Deming |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Timothy J. Deming (Summerland, California) |
ABSTRACT | Methods and compositions for the generation of polypeptides having varied material properties are disclosed herein. Methods include means for initiating the polymerization of aminoacid-N-carboxyanhydride (NCA) monomer by combining the monomer with an amido-containing metallacycle, for making self assembling amphiphilic block copolypeptides and related protocols for adding oligo(ethyleneglycol) functionalized aminoacid-N-carboxyanhydrides (NCAs) to polyaminoacid chains. Additional methods include means of adding an end group to the carboxy terminus of a polyaminoacid chain by reacting an alloc-protected amino acid amide with a transition metal-donor ligand complex to forming an amido-amidate metallacycle for use in further polymerization reactions. Novel compositions for use in peptide synthesis and design including five and six membered amido-containing metallacycles and block copolypeptides are also disclosed. |
FILED | Friday, November 14, 2003 |
APPL NO | 10/712967 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/333 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07329769 | Smith, III |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Milton R. Smith, III (East Lansing, Michigan) |
ABSTRACT | A process for producing a ring-substituted arene borane which comprises reacting a ring-substituted arene with an HB organic compound in the presence of a catalytically effective amount of an iridium or rhodium complex with three or more substituents, excluding hydrogen, bonded to the iridium or rhodium and a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium, to form the ring-substituted arene borane. Also provided are catalytic compounds for catalyzing the process comprising an iridium or rhodium complex with three or substituents, excluding hydrogen, bonded to the iridium or rhodium and optionally, a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium. |
FILED | Tuesday, March 29, 2005 |
APPL NO | 11/092076 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 558/287 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330076 | Komijani et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Abbas Komijani (Los Angeles, California); Seyed-Ali Hajimiri (Pasadena, California); Scott D. Kee (Tustin, California); Ichiro Aoki (Arcadia, California) |
ABSTRACT | Reconfigurable distributed active transformers are provided. The exemplary embodiments provided allow changing of the effective number and configuration of the primary and secondary windings, where the distributed active transformer structures can be reconfigured dynamically to control the output power levels, allow operation at multiple frequency bands, maintain a high performance across multiple channels, and sustain desired characteristics across process, temperature and other environmental variations. Integration of the distributed active transformer power amplifiers and a low noise amplifier on a semiconductor substrate can also be provided. |
FILED | Friday, October 06, 2006 |
APPL NO | 11/544895 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Amplifiers 330/276 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330152 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Shenghui Zhang (Beijing, China PRC); Jennifer T. Bernhard (Champaign, Illinois); Gregory H. Huff (Champaign, Illinois); Garvin Cung (Columbia, Maryland) |
ABSTRACT | An antenna device includes a dielectric layer, an electrical ground layer carried on one side of the dielectric layer, and an antenna arrangement carried on another side of the dielectric layer. This arrangement includes two parasitic microstrip elements and a microstrip signal element. The signal element is structured to radiate an electromagnetic signal in response to application of a corresponding electrical communication signal. The parasitic antenna elements extend along opposing longitudinal sides of the signal element and each includes an adjustable component operatively connected between two microstrips. The adjustable component is structured to selectively adjust operable length of a selected one of the parasitic antenna elements to change a maximum radiation direction of the antenna device. |
FILED | Monday, October 24, 2005 |
APPL NO | 11/257382 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07328625 | Sundermeyer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
INVENTOR(S) | Jeffry Neil Sundermeyer (Dunlap, Illinois); Nitin R. Patel (Peoria, Illinois); Ryan Paul Allgaier (East Peoria, Illinois); Don Sit (Peoria, Illinois); Timothy Allen Vik (Sparland, Illinois); Jeffrey Dale Baskett (Peoria, Illinois); Hiroko Kyuba (Peoria, Illinois); Daniel Kimsey Dunn, III (Dunlap, Illinois); Byron Edwin Truax (Dunlap, Illinois); Burton Roland Clarke (Cuba, Illinois) |
ABSTRACT | A method and method of estimating fatigue life of a structure is disclosed. In one embodiment, the method may include determining strain on the structure using a plurality of gauges positioned on the structure. The method may also include detecting a parameter of the structure with a plurality of sensors positioned on the structure. Further, the method includes converting the detected parameter and the determined strain to proportional loads acting on the structure and transforming the proportional loads to coordinate system data associated with the structure. Based on the coordinate system data, the fatigue life of the structure may be estimated. |
FILED | Friday, September 16, 2005 |
APPL NO | 11/227157 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/806 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07330404 | Peng et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
INVENTOR(S) | Chubing Peng (Pittsburgh, Pennsylvania); William Albert Challener (Sewickley, Pennsylvania); Ibrahim Kursat Sendur (Pittsburgh, Pennsylvania) |
ABSTRACT | An optical transducer comprises an optical element for directing an electromagnetic wave to a focal region and a metallic nano-structure having a longitudinal axis substantially parallel to an electric field of the electromagnetic wave, the metallic nano-structure being positioned outside of the optical element, wherein the electromagnetic wave produces surface plasmons on the metallic nano-structure. A cladding material having a refractive index differing from the refractive index of the optical element can be positioned adjacent to a surface of the metallic nano-structure. Magneto-optical recording heads that include the transducers and disc drives that include the magneto-optical recording heads are also included. |
FILED | Friday, October 10, 2003 |
APPL NO | 10/683385 |
ART UNIT | 2627 — Selective Visual Display Systems |
CURRENT CPC | Dynamic information storage or retrieval 369/13.330 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07330034 | Pelletier et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Mathew G. Pelletier (Lubbock, Texas); Michael E. Gvili (Wayland, Massachusetts) |
ABSTRACT | A process for measuring the moisture content and the mass-moisture content of materials is presented that requires no air reference or calibration sequence. A microwave signal is split into a reference and a transmission signal, and the reference signal is applied directly to the phase detector, whereas the transmission signal is first transmitted through the sample before being presented to the other side of the phase detector. This measurement provides a phase-constant measurement that is due to the dielectric characteristics of the material under test. The system measures the material's phase-constant across a band of frequencies. The slope of the phase-constant versus frequency is then utilized to predict the density of the material which is then combined with the corrected phase-constant measurement to calculate the moisture content of the material. |
FILED | Tuesday, December 14, 2004 |
APPL NO | 11/011705 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/640 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 07330736 | Redi |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | Jason Keith Redi (Belmont, Massachusetts) |
ABSTRACT | The invention relates to communications devices for reduced energy communications in an ad hoc network. The communication device includes a first low powered transceiver for initiating communications with other communications devices and a second transceiver for transmitting data messages to the other communications devices once communication is initiated. The communication device also includes a communications control processor for determining times at which the other communications devices will be available to receive communications based on scheduling data received from those communication devices. |
FILED | Thursday, March 10, 2005 |
APPL NO | 11/078257 |
ART UNIT | 2617 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Telecommunications 455/553.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 07329359 | Roark |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Eltron Research, Inc. (Boulder, Colorado) |
INVENTOR(S) | Shane E Roark (Boulder, Colorado) |
ABSTRACT | A method of destroying an organic compound in liquid media comprising: contacting said liquid media with a catalyst of formula: nN/Ce1−xZrcBbB′b′B″b″O2−δ wherein n is a percentage from 0 to 25; N is one or more metals selected from the group consisting of Pt, Pd, Rh, Ru, Re, Os and Ir; x=b+b′+b″+c; b, b′, and b″ are each, independently of one another, 0 to 0.99; x≦0.7; B, B′ and B″ are independently selected from the group consisting of Ti, V, Mn, Fe, Co, Cr, Ni, Au, Ag and Cu; c is between 0 and 0.2; δ is a number which renders the catalyst charge neutral; provided that at least one of b, b′ and b″ is nonzero; provided that when B is Mn, b′ or c or n is nonzero at a temperature and pressure sufficient to destroy an organic compound is provided. Also provided are catalyst compositions for destroying at least one organic compound in liquid media comprising a catalyst and a support. |
FILED | Wednesday, September 25, 2002 |
APPL NO | 10/256212 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Liquid purification or separation 210/763 |
VIEW PATENT | @ USPTO: Full Text PDF |
Federal Reserve Bank (FED)
US 07330835 | Deggendorf |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Federal Reserve Bank of Minneapolis (Minneapolis, Minnesota) |
INVENTOR(S) | Theresa M. Deggendorf (Coon Rapids, Minnesota) |
ABSTRACT | Tracking and reporting status of automated clearing house (“ACH”) transactions. An ACH operator receives an ACH file comprising an ACH batch comprising an ACH transaction item for ACH processing. The operator tracks a status of the ACH file, batch, and item during multiple ACH processing events. A customer communicates a query for the status of the ACH file, batch, or item. The operator retrieves the tracked status of the ACH file, batch, or item and presents the tracked status to the customer. The ACH processing events typically comprise receiving the ACH file, confirming the ACH file, approving the ACH file, processing the ACH file, processing the ACH batch in the ACH file, and processing the ACH transaction item in the ACH batch. The operator can present a graphical depiction of errors the ACH file header, batch header, or item record detail. |
FILED | Thursday, October 30, 2003 |
APPL NO | 10/697774 |
ART UNIT | 3691 — Business Methods - Finance/Banking/ Insurance |
CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/39 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
US 07328921 | Miciukiewicz |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
INVENTOR(S) | Michael J. Miciukiewicz (Trumbull, Connecticut) |
ABSTRACT | A device which allows fluid to enter and/or exit the device axially or radially thru multiple ports, on and/or offset from the axis of rotation. One end of the assembly can be rotated axially with respect to the other while keeping fluids isolated from each other. Compared to existing multi-path fluid swivel joint designs, this approach is simple in construction, compact in size, and exhibits a relatively low pressure drop. |
FILED | Monday, April 04, 2005 |
APPL NO | 11/097194 |
ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Pipe joints or couplings 285/275 |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 07330530 | Chapman |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Illinois Institute of Technology (Chicago, Illinois) |
INVENTOR(S) | Leroy Dean Chapman (Saskatoon, Canada) |
ABSTRACT | A method for detecting an enhanced image of an object by independently analyzing, detecting, digitizing, and combining images acquired on a high and a low angle side of a rocking curve of a crystal analyzer. An x-ray beam generated by a line x-ray source is collimated by a crystal monochromator including two non-matching crystals to form an x-ray area beam. The x-ray area beam is transmitted through an object to be imaged and onto an image detector and the image is digitized. The digitized images are simultaneously solved, preferably on a pixel-by-pixel basis, to derive an enhanced image which has dramatically improved contrast and spatial resolution over an image acquired through conventional radiology methods. |
FILED | Monday, October 04, 2004 |
APPL NO | 10/957884 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/85 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07329765 | Burli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | GeneSoft Pharmaceuticals, Inc. (South San Francisco, California) |
INVENTOR(S) | Roland W. Burli (San Francisco, California); Eldon E. Baird (Half Moon Bay, California); Matthew J. Taylor (San Francisco, California); Jacob A. Kaizerman (Redwood CitySo. San Francisco, California); Wenhao Hu (San Mateo, California) |
ABSTRACT | Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity. |
FILED | Tuesday, November 30, 2004 |
APPL NO | 11/001237 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 549/57 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 12, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080212.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page