FedInvent™ Patents
Patent Details for Tuesday, February 19, 2008
This page was updated on Monday, March 27, 2023 at 12:55 AM GMT
Department of Health and Human Services (HHS)
| US 07331251 | Das et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Idaho State University (Pocatello, Idaho) |
| INVENTOR(S) | Nandita G. Das (Carmel, Indiana); Sudip K. Das (Carmel, Indiana); Madhu S. Surapaneni (Wheeling, Illinois) |
| ABSTRACT | The invention is a method and device for determining dissolution of a solid compound within the oral cavity. The device models dissolution within the oral cavity with a flow-through cell containing a solid compound and physiological amounts of simulated saliva. The device supplies and removes the simulated saliva at rates similar to production and loss of saliva within the oral cavity. The simulated saliva interaction with the solid compound mimics saliva interaction with a solid compound within the oral cavity. Dissolution of solid compound is determined from simulated saliva collected from the flow-through cell outflow. |
| FILED | Wednesday, June 22, 2005 |
| APPL NO | 11/158903 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/866 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331926 | Varghese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Tomy Varghese (Madison, Wisconsin); Udomchai Techavipoo (Madison, Wisconsin); Quan Chen (Madison, Wisconsin); James A. Zagzebski (Madison, Wisconsin) |
| ABSTRACT | Ultrasonic signals obtained at a range of angles are fit to a material independent model to derive both axial and lateral strain and thus parameters dependent on lateral strain including Poisson's ratio and shear strain. |
| FILED | Monday, February 23, 2004 |
| APPL NO | 10/784526 |
| ART UNIT | 3768 — Electrical Circuits and Systems |
| CURRENT CPC | Surgery 6/443 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332111 | Grothe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Colorado (Boulder, Colorado) |
| INVENTOR(S) | Willy Grothe (Boulder, Colorado); Daniel Jarmer (Boulder, Colorado); Corinne Lengsfeld (Denver, Colorado); Theodore Randolph (Niwot, Colorado) |
| ABSTRACT | The present invention provides methods and devices for producing particles with an average diameter less than about 15 μm using the precipitation with compressed fluid-antisolvent (PCA) process and the carbon-dioxide assisted nebulization with a bubble dryer (CAN-BD) process. In the methods and nozzles of the invention, at least one jet of supercritical or near-supercritical fluid and at least one jet of solution interact to mix the supercritical or near-supercritical fluid and the solution within a chamber. The solution contains at least one solvent and at least one solute. At least one of the jets is a swirling jet. To form particles, the solvent and supercritical or near-supercritical fluid are then injected into a PCA or a CAN-BD process chamber. The degree of mixing depends in part on the power input into the mixing chamber. Power inputs of about 6.5×109 W/m3 enhance the degree of mixing and allow production of nanoscale particles with the PCA process. The nanoscale particles have a size distribution so that polydispersity is less than about 1.75. |
| FILED | Wednesday, July 10, 2002 |
| APPL NO | 10/483194 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332161 | Colman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Temple University - Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); Bristol-Myers Squibb Pharma Company (Princeton, New Jersey) |
| INVENTOR(S) | Robert W. Colman (Moylan, Pennsylvania); Shaker A. Mousa (New London, Pennsylvania) |
| ABSTRACT | Antibodies directed against an antigenic determinant of high molecular weight kininogen domain 5, particularly a determinant located in the region formed by light chain amino acids Gly(440) to Lys(502), inhibit angiogenesis. |
| FILED | Monday, January 30, 2006 |
| APPL NO | 11/343003 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332167 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | David D. Roberts (Bethesda, Maryland); Sizhuang (Steve) Yan (Bethesda, Maryland) |
| ABSTRACT | Three hemoglobin-response genes in the pathogenic yeast Candida albicans are disclosed. The expression of these genes is specifically induced when the organism is exposed to hemoglobin during disseminated infections. The invention relates to the nucleic acid and amino acid sequences of these hemoglobin-response genes. The invention also relates to diagnostic methods, kits and compositions which employ the nucleic acid and amino acid sequences of the invention. |
| FILED | Friday, February 18, 2005 |
| APPL NO | 11/060295 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332171 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | David H. Walker (Galveston, Texas); Xue-Jie Yu (Galveston, Texas) |
| ABSTRACT | The 28-kDa outer membrane proteins (P28) of Ehrlichia chaffeensis are encoded by a multigene family consisting of 21 members located in a 23-kb DNA fragment in the genome of E. chaffeensis. Fifteen of these proteins are claimed herein as novel sequences. The amino acid sequence identity of the various P28 proteins was 20-83%. Six of 10 tested p28 genes were actively transcribed in cell culture grown E. chaffeensis. RT-PCR also indicated that each of the p28 genes was monocistronic. These results suggest that the p28 genes are active genes and encode polymorphic forms of the P28 proteins. The P28s were also divergent among different isolates of E. chaffeensis. The large repertoire of the p28 genes in a single ehrlichial organism and antigenic diversity of the P28 among the isolates of E. chaffeensis suggest that the P28s may be involved in immune avoidance. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/369293 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/234.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332278 | Lowery et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Bellbrook Labs, LLC (Madison, Wisconsin) |
| INVENTOR(S) | Robert G. Lowery (Madison, Wisconsin); John Majer (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to methods for detecting, quantifying and high throughput screening of donor-products and the catalytic activities generating the donor-products in group-transfer reactions. The invention further provides immunoassays, antibodies and kits that may be used to practice the methods of the invention. |
| FILED | Friday, January 30, 2004 |
| APPL NO | 10/769578 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332280 | Levy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald Levy (Stanford, California); Mark A. Wechser (Foster City, California); Izidore S. Lossos (Miami, Florida); Robert J. Tibshirani (Palo Alto, California); Ash A. Alizadeh (San Mateo, California); David Botstein (Princeton, New Jersey) |
| ABSTRACT | Methods and kits for classifying patients having diffuse large B-cell lymphoma (DLBCL) based upon expression of a plurality of genes are disclosed. Real-time quantitative RT-PCR can be used to measure expression values. Correlating expression values of the plurality of genes in a tumor sample from the patient to reference expression values obtained from DLBCL patients can stratify patients in the classification groups. The methods and kits can be used to predict overall patient survival. |
| FILED | Wednesday, March 03, 2004 |
| APPL NO | 10/792374 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332282 | Fink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | John K. Fink (Ann Arbor, Michigan); Shirley Rainier (Sylvania, Ohio); Robert D. Nicholls (Philadelphia, Pennsylvania); Jinghua Chai (Ardmore, Pennsylvania) |
| ABSTRACT | The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins. |
| FILED | Thursday, August 19, 2004 |
| APPL NO | 10/921742 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332285 | Barany et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Regents of the University of Minnesota (Minneapolis, Minnesota); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Francis Barany (New York, New York); Matthew Lubin (Rye Brook, New York); George Barany (Falcon Heights, Minnesota); Robert P. Hammer (Baton Rouge, Louisiana) |
| ABSTRACT | The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain reaction (PCR) mixture, detecting the amplified ligation product, and identifying the target nucleotide sequence. Such coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence differences. |
| FILED | Tuesday, October 31, 2006 |
| APPL NO | 11/590383 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332290 | Rubin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Mark A. Rubin (Newton, Massachusetts); Arul M. Chinnaiyan (Plymouth, Michigan); Bharathi Laxman (Ann Arbor, Michigan); Arun Sreekumar (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. The present invention also provides novel markers useful for the diagnosis, characterization, and treatment of prostate cancers. In particular, the present invention provides methods and compositions for the detection of α-methylacyl-CoA racemase (AMACR) in the urine as a marker for prostate cancer detection. |
| FILED | Friday, July 30, 2004 |
| APPL NO | 10/909035 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07332296 — Screening assay for enzymes involved in pathophysiology using SELDI-TOF mass spectrometry
| US 07332296 | Elased et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wright State University (Dayton, Ohio) |
| INVENTOR(S) | Khalid M. Elased (Bellbrook, Ohio); Mariana Morris (Yellow Springs, Ohio) |
| ABSTRACT | The invention provides methods for quantifying enzymatic activity of an enzyme with a known substrate. The methods employ SELDI-TOF mass spectrometry, and are suitable, in particular, for assaying aspects of the renin-angiotensin system. The methods may be utilized to assess and/or monitor biological conditions associated with the renin-angiotensin system prior to the manifestation of known physiological and biomarkers for such conditions. The methods are suitable for analysis of pharmacological effectors of the renin-angiotensin system, and are particularly suitable for automation and high-throughput screening assay design. |
| FILED | Friday, December 02, 2005 |
| APPL NO | 11/292806 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332298 | Kornbluth |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard S. Kornbluth (La Jolla, California) |
| ABSTRACT | A method for constructing stable bioactive fusion proteins of the difficult to express tum or necrosis factor superfamily (TNFSF), and particularly members CD40L (CD 154) and RANKL/TRANCE, with collectins, particularly pulmonary surfactant protein D (SPD) is described. Single trimers of these proteins lack the full stimulatory efficacy of the natural membrane forms of these proteins in many cases. The multimeric nature of these soluble fusion proteins enables them to engage multiple receptors on the responding cells, thereby, mimicking the effects of the membrane forms of these ligands. For CD40L-SPD, the resulting protein stimulates B cells, macrophages, and dendritic cells, indicating its potential usefulness as a vaccine adjuvant. The large size of these fusion proteins makes them less likely to diffuse into the circulation, thereby limiting their potential systemic toxicity. This property may be especially useful when these proteins are injected locally as a vaccine adjuvant or tumor immunotherapy agent to prevent them from diffusing away. In addition, these and other TNFSF-collectin fusion proteins present new possibilities for the expression of highly active, multimeric, soluble TNFSF members. |
| FILED | Tuesday, March 22, 2005 |
| APPL NO | 11/087348 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332307 | Carlton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); Exponential Biotherapies, Inc. (New York, New York) |
| INVENTOR(S) | Richard M. Carlton (Port Washington, New York); Carl R. Merril (Rockville, Maryland); Sankar L. Adhya (Gaithersburg, Maryland) |
| ABSTRACT | The present invention is directed to bacteriophage therapy, using methods which enable the bacteriophage to delay inactivation by any and all parts of the host defense system (HDS) against foreign objects. The HDS normally reduces the number of bacteriophage in an animal, which decreases the efficiency of the bacteriophage in killing the host bacteria present during an infection. Disclosed is a method of producing bacteriophage modified for anti-HDS purposes by physico-chemical alteration of the bacteriophage surface proteins, so that the altered bacteriophage remain active in the body for longer periods of time than the unmodified bacteriophage. |
| FILED | Thursday, September 11, 2003 |
| APPL NO | 10/659698 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332308 | Benkovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J. Benkovic (State College, Pennsylvania); Marc Ostermeier (Baltimore, Maryland); Stefan Lutz (State College, Pennsylvania); Andrew E. Nixon (Quincy, Massachusetts) |
| ABSTRACT | A series of methods that utilize the incremental truncation of nucleic acids are described to create a plurality of modified nucleic acids and hybrid polypeptides. A plurality of substantially all possible single base-pair deletions of a given nucleic acid sequence is created. A method of making shuffled incremental truncated nucleic acids, which is independent of nucleic acid sequence homology, is also described. These methods can be used in protein engineering, protein folding, protein evolution, and the chemical synthesis of novel hybrid proteins and polypeptides. |
| FILED | Wednesday, November 15, 2000 |
| APPL NO | 09/718465 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332322 | Frolov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ilya Frolov (Galveston, Texas); Elena Frolova (Galveston, Texas) |
| ABSTRACT | The present invention provides a Venezuelan equine encephalitis virus replicon RNA useful in the development of stable lines of mammalian, avian and insect cells in which these replicons will persistently replicate. Venezuelan equine encephalitis (VEE) virus replicons contain a number of unique adaptive mutations that make the replicons noncytopathic. The replicons remain resistant to IFN-α/β. Replicon replication leads to high-level production of heterologous proteins, which are encoded by the replicons' genome and are under the control of a viral subgenomic promoter. Also provided are methods of screening for inhibitory compounds of Venezuelan equine encephalitis virus replication and eastern equine encephalitis virus replication. |
| FILED | Wednesday, September 14, 2005 |
| APPL NO | 11/227671 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/236 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332324 | Cole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Garry T. Cole (San Antonio, Texas); Xia Chen (Madison, Wisconsin); Kalpathi R. Seshan (Numgambakkan, India); Chiung-Yu Hung (Helotes, Texas); Jianmin Xue (San Antonio, Texas); Jieh-Juen Yu (Helotes, Texas) |
| ABSTRACT | A Coccidioides spp. fungus that is attenuated by the loss of endosporulation potential of the fungus wherein said fungus does not replicate when transformed into the parasitic phase. |
| FILED | Friday, December 02, 2005 |
| APPL NO | 11/292431 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/254.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332329 | Wark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Alastair William Wark (Irvine, California); Hye Jin Lee (Irvine, California); Robert Marcus Corn (Corona del Mar, California); Voula Kodoyianni (Madison, Wisconsin) |
| ABSTRACT | A substrate for testing a carrier liquid for biomolecules using SPR or other techniques provides a metallic island surrounded by a hydrophobic layer, the islands being a location for the attachment of probe molecules. The hydrophobic layer may also be a dielectric material providing improved sensitivity in SPR imaging. |
| FILED | Wednesday, September 21, 2005 |
| APPL NO | 11/231626 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332334 | Xia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Lijun Xia (Edmond, Oklahoma); Rodger P. McEver (Oklahoma City, Oklahoma) |
| ABSTRACT | A method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method, an effective amount of an α1,3-fucosyltransferase, e.g., α1,3-fucosyltransferase VI, is used in vitro to treat cord blood-derived hematopoietic stem cells to convert non-functional PSGL-1 or other ligands on the cell surface into functional forms that bind selectins, especially P-selectin or E-selectin. The treated cells have enhanced effectiveness in reconstituting bone marrow in patients in need of such therapy. |
| FILED | Friday, January 30, 2004 |
| APPL NO | 10/769686 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/366 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332335 | Honkanen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | South Alabama Medical Science Foundation (Mobile, Alabama) |
| INVENTOR(S) | Richard E. Honkanen (Mobile, Alabama) |
| ABSTRACT | The invention provides a method of increasing expression of p21WAF1/Cip 1 in cells to decrease proliferation of the cells, the method comprising decreasing levels of PP5 protein in the cells. The invention further provides a method of treating or preventing an abnormal condition resulting from a defect in a tumor suppressor gene in a subject that results in decreased induction of p21WAF1/Cip 1 in the cells of the subject, the method comprising administering to the subject an amount of a compound effective to decrease levels of PP5 protein in the cells of the subject. |
| FILED | Wednesday, February 05, 2003 |
| APPL NO | 10/358851 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332343 | Anslyn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Eric V. Anslyn (Austin, Texas); J. Frantz Folmer-Andersen (Austin, Texas); Lei Zhu (Tallahassee, Florida) |
| ABSTRACT | The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples calorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical calculation. Concentration may also be determined. The assay may involve two independent absorption measurements. On suitable group of enantiomeric molecules to be assayed include α-hydroxyacids. The inherent relationship between the absorbance of the indicator-displacement ensemble and the overall concentration and ee of the analyte is established through solution equilibria. The invention also includes use of the assay in drug screening and manufacturing, high throughput screening of catalysts and kits for use in conducting assays of the invention. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/036642 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332355 | Hsieh-Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Linda Hsieh-Wilson (San Marino, California); Nelly Khidekel (Pasadena, California); Hwan-Ching Tai (Pasadena, California); Sabine Arndt (Dortmund, Germany) |
| ABSTRACT | The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations. The methods can be used to detect O-GlcNAc post-translational modifications on proteins on which such modifications were undetectable using other techniques. In one embodiment, the method exploits the ability of an engineered mutant of β-1,4-galactosyltransferase to selectively transfer an unnatural ketone functionality onto O-GlcNAc glycosylated proteins. Once transferred, the ketone moiety serves as a versatile handle for the attachment of biotin, thereby enabling detection of the modified protein. The approach permits the rapid visualization of proteins that are at the limits of detection using traditional methods. Further, the preferred embodiments can be used for detection of certain disease states, such as cancer, Alzheimer's disease, neurodegeneration, cardiovascular disease, and diabetes. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/990767 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332469 | Idell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Steven Idell (Tyler, Texas) |
| ABSTRACT | The present invention relates to methods of preventing or decreasing the severity of scarring in a subject comprising: obtaining a pharmaceutical composition comprising a single chain urokinase plasminogen activator molecule (scuPA) or a scuPA mimetic; and administering the pharmaceutical composition to a subject; wherein scarring in the subject is either prevented or decreased relative to an amount of scarring that would be expected if the pharmaceutical composition were not administered to the subject. The invention also relates to methods of screening for compounds that prevent or decrease the severity of scarring in a subject. |
| FILED | Friday, April 04, 2003 |
| APPL NO | 10/407821 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332470 | Fleiszig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Research Foundation of State University of New York (Albany, New York) |
| INVENTOR(S) | Suzanne Fleiszig (Oakland, California); David J. Evans (Oakland, California); Robert Sack (Brookhaven, New York) |
| ABSTRACT | The use of collectins and/or surfactant proteins for the treatment and prevention of ocular disease. |
| FILED | Wednesday, April 14, 2004 |
| APPL NO | 10/823819 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332479 | Fink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Mitchell P. Fink (Pittsburgh, Pennsylvania); Russell L. Delude (Pittsburgh, Pennsylvania); Xianonan Han (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of prophylaxis or treatment of inflammatory conditions, including, but not limited to, intestinal epithelial inflammation due to intestine-specific conditions (e.g., Crohn's disease or ulcerative colitis) or systemic causes of inflammation (e.g., endotoxemia, sepsis, hemorrhagic shock/resuscitation or pancreatitis) is disclosed. In the method of the invention, an affected patient is administered a therapeutically effective amount of a composition including an NAD-related compound, in a form that is accessible to a receptor molecule, conveyed in a pharmaceutically acceptable carrier vehicle. NAD-related compounds include nicotinamide adenine dinucleotide (NAD+), cyclic adenosine diphosphate ribose (cADPR), or functionally equivalent analogues, derivatives, metabolites or agonists thereof or prodrugs therefor. Also disclosed are ex vivo and in vivo assay methods to test candidate compounds for activity, kits for carrying out the therapeutic methods or the assay methods of the invention and articles of manufacture that include compositions for use in the methods of the invention and instructions for the use thereof. |
| FILED | Wednesday, September 10, 2003 |
| APPL NO | 10/659063 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332580 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gregory P. Adams (Philadelphia, Pennsylvania); Eva M. Horak (Philadelphia, Pennsylvania); Louis M. Weiner (Philadelphia, Pennsylvania); James D. Marks (Kensington, California) |
| ABSTRACT | Bispecific single chain antibody molecules are disclosed which may be used to advantage to treat various forms of cancer associated with the overexpression of members of the EGFR protein family. |
| FILED | Friday, April 04, 2003 |
| APPL NO | 10/406830 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332585 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the California University (Oakland, California); Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gregory P. Adams (Hatboro, Pennsylvania); Eva M. Horak (West Orange, New Jersey); Louis M. Weiner (Philadelphia, Pennsylvania); James D. Marks (Kensington, California) |
| ABSTRACT | Bispecific single chain antibody molecules are disclosed which may be used to advantage to treat various forms of cancer associated with the overexpression of members of the EGFR protein family. |
| FILED | Wednesday, June 15, 2005 |
| APPL NO | 11/154103 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332590 | Nacht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as Represented by the Department of Health and Human Services (Washington, District of Columbia); Genzyme Corporation (Cambridge, Massachusetts); The Johns Hopkins University of Medicine (Baltimore, Maryland) |
| INVENTOR(S) | Mariana Nacht (Belmont, Massachusetts); Tatiana Dracheva (Rockville, Maryland); David Sidransky (Baltimore, Maryland); Stephen Madden (Sudbury, Massachusetts); Jin Jen (Brookeville, Maryland) |
| ABSTRACT | We used hierarchical clustering to examine gene expression profiles generated by serial analysis of gene expression (SAGE) in a total of nine normal lung epithelial cells and non-small cell lung cancers (NSCLC). Separation of normal and tumor samples, as well as histopathological subtypes, was evident using the 3,921 most abundant transcript tags. This distinction remained when just 115 highly differentially expressed transcript tags were used. Furthermore, these 115 transcript tags clustered into groups that were suggestive of the unique biological and pathological features of the different tissues examined. Adenocarcinomas were characterized by high-level expression of small airway-associated or immunologically related proteins, while squamous cell carcinomas overexpressed genes involved in cellular detoxification or antioxidation. The messages of two p53-regulated genes, p21WAF1/CIP1 and 14-3-3σ, were consistently under-expressed in the adenocarcinomas, suggesting that the p53 pathway itself might be compromised in this cancer type. Gene expression observed by SAGE were consistent with the results obtained by quantitative real-time PCR or cDNA array analyses using 43 additional lung tumor and normal samples. Thus, although derived from only a few tissue libraries, molecular signatures of non-small cell lung cancer derived from SAGE most likely represent an unbiased yet distinctive molecular signature for human lung cancer. |
| FILED | Friday, August 16, 2002 |
| APPL NO | 10/486844 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332591 | Sheffield et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Val C. Sheffield (Iowa City, Iowa); Edwin Stone (Iowa City, Iowa); Thomas Casavant (Iowa City, Iowa); Terry Braun (Iowa City, Iowa); Darryl Nishimura (Coralville, Iowa) |
| ABSTRACT | The present invention relates to the designation of ADP-ribosylation factor-like 6 as the BBS3 gene, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described. |
| FILED | Tuesday, December 21, 2004 |
| APPL NO | 11/019081 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332598 | Tsien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Robert E. Campbell (San Diego, California) |
| ABSTRACT | Non-oligomerizing fluorescent proteins, which are formed by operatively linking two or more monomers of a fluorescent protein, or which are derived from a fluorescent protein having at least one mutation that reduces or eliminates the ability of the fluorescent protein to oligomerize, are provided. The non-oligomerizing fluorescent proteins can be derived from a naturally occurring green fluorescent protein, a red fluorescent protein, or other fluorescent protein, or a fluorescent protein related thereto. Also provided is a fusion protein, which includes a non-oligomerizing fluorescent protein linked to at least one polypeptide of interest. In addition, a polynucleotide encoding a non-oligomerizing fluorescent protein is provided, as is a recombinant nucleic acid molecule, which includes polynucleotide encoding a non-oligomerizing fluorescent protein operatively linked to at least a second polynucleotide. Vectors and host cells containing such polynucleotides also are provided, as are kits containing one or more non-oligomerizing fluorescent proteins or encoding polynucleotides or constructs derived therefrom. Further provided are methods of making and using the proteins and polynucleotides. |
| FILED | Tuesday, July 06, 2004 |
| APPL NO | 10/885988 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332611 | Turos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Edward Turos (Tampa, Florida); Rajesh Kumar Mishra (Rochester, Minnesota) |
| ABSTRACT | This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylcoccus aureus (MRSA), and Bacillus spp., including Bacillus anthracis. |
| FILED | Monday, May 08, 2006 |
| APPL NO | 11/382157 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332613 | Gygi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Steven P. Gygi (Foxboro, Massachusetts); Scott Anthony Gerber (Brookline, Massachusetts); Carlos Augusto Gartner (Somerville, Massachusetts) |
| ABSTRACT | The invention provides non-affinity based isotope tagged peptides, chemistries for making these peptides, and methods for using these peptides. In one aspect, tags comprise a reactive site (RS) for reacting with a molecule on a protein to form a stable association with the peptide (e.g., a covalent bond) and an anchoring site (AS) group for reversibly or removably anchoring the tag to a solid phase such as a resin support. Anchoring may be direct or indirect (e.g., through a linker molecule). Preferably, the anchoring site comprises a biotin compound. Preferably, the tag comprises a mass-altering label, such as a stable isotope, such that association of the tag with the peptide can be monitored by mass spectrometry. The reagents can be used for rapid and quantitative analysis of proteins or protein function in mixtures of proteins. |
| FILED | Monday, June 07, 2004 |
| APPL NO | 10/863589 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 548/303.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332643 | Ghetti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Indiana University and Technology Corp. (Indianapolis, Indiana) |
| INVENTOR(S) | Bernardino Ghetti (Indianapolis, Indiana); Ruben Vidal (Indianapolis, Indiana) |
| ABSTRACT | Nucleic acids encoding a novel ferritin light chain variant, a ferritin light chain variant polypeptide, ferritin light chain variant polypeptide-specific antibodies, and methods of use thereof are provided herein. Also provided are methods to screen and identify agents capable of modulating the activity of the ferritin light chain variant. |
| FILED | Tuesday, October 14, 2003 |
| APPL NO | 10/684742 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332645 | Leonard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Warren J. Leonard (Bethesda, Maryland); Katsutoshi Ozaki (Tochigi, Japan); Rosanne Spolski (Ellicott City, Maryland) |
| ABSTRACT | A transgenic mouse is disclosed herein whose somatic and germ cells comprise a disrupted IL-21 receptor gene, the disruption being sufficient to inhibit the binding of IL-21 to an IL-21 receptor, and a disrupted IL-4 gene, the disruption being sufficient to inhibit the production of IL-4 or the binding of IL-4 to the IL-4 receptor. A mouse homozygous for the disrupted IL-21 receptor gene and homozygous for the disrupted IL-4 gene has diminished B cell function. A method is disclosed for altering a B cell activity. The method includes administering a therapeutically effective amount of an agent that interferes with the interaction of IL-21 with an IL-21 receptor, thereby altering the B cell activity. A method is also disclosed for of treating a subject with Job's disorder or atopic disease. A method is also disclosed for treating or preventing an allergic reaction in a subject. A method is also disclosed for treating a subject with an autoimmune or antibody mediated disorder. |
| FILED | Thursday, December 30, 2004 |
| APPL NO | 11/027868 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332647 | Lin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shuo Lin (Los Angeles, California) |
| ABSTRACT | The disclosure provided herein teaches that fertile transgenic fish can be generated by nuclear transfer using cultured cells as embryonic fibroblasts. |
| FILED | Wednesday, June 11, 2003 |
| APPL NO | 10/517880 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332700 | Ishimoto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce Masato Ishimoto (Palo Alto, California); Tim Hawks (Menlo Park, California) |
| ABSTRACT | In a photomultiplier tube (PMT) device having a plurality of dynodes provided between a cathode and an anode, a cancellation circuit provides two different modulation signals to the PMT to cancel the effects of the modulation signals upon the output of the PMT. For one embodiment, a cancellation circuit includes an input to receive an input modulation signal, a first output to provide a first output modulation signal to a first dynode, and a second output to provide a second output modulation signal to a second dynode, wherein the first and second output modulation signals are 180 degrees out-of-phase. For another embodiment, the cancellation circuit provides the input modulation signal to one of the PMT's dynodes, and also subtracts the input modulation signal from the PMT's output signal. |
| FILED | Tuesday, April 26, 2005 |
| APPL NO | 11/115501 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332908 | Nayak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Krishna S. Nayak (Los Angeles, California); Brian A. Hargreaves (San Francisco, California) |
| ABSTRACT | Disclosed is a wideband SSFP, wherein a standard balanced SSFP MRI sequence is played with repetition times of alternating lengths, TR and TRs, where TRs<TR. The result is significantly improved tradeoff between signal bandwidth and available acquisition interval lengths. This is particularly important as it enables the combination of balanced SSFP with high field imaging for many applications such as cardiac, musculoskeletal and abdominal imaging. |
| FILED | Thursday, May 04, 2006 |
| APPL NO | 11/381601 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333588 | Mistretta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Charles A. Mistretta (Madison, Wisconsin); Thomas R. Mackie (Madison, Wisconsin) |
| ABSTRACT | An x-ray computed tomography system uses a broad area x-ray emitter and detector to allow both in plane and out of plane x-ray projections not restrained to spiral or helical scans. |
| FILED | Friday, December 13, 2002 |
| APPL NO | 10/498383 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333591 | Earl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Matt A. Earl (Columbia, Maryland); David M. Shepard (Severn, Maryland); Xinsheng Yu (Clarksville, Maryland) |
| ABSTRACT | A new optimization method for generating treatment plans for radiation oncology is described and claimed. This new method works for intensity modulated radiation therapy (IMRT), intensity modulated arc therapy (IMAT), and hybrid IMRT. |
| FILED | Friday, October 27, 2006 |
| APPL NO | 11/588294 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333642 | Green |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | SRI International, Inc. (Menlo Park, California) |
| INVENTOR(S) | Philip S. Green (Redwood City, California) |
| ABSTRACT | In a telemanipulation system for manipulating objects located in a workspace at a remote worksite by an operator from an operator's station, such as in a remote surgical system, the remote worksite having a manipulator with an end effector for manipulating an object at the workspace, such as a body cavity, a controller including a hand control at the control operator's station for remote control of the manipulator, an image capture device, such as a camera, and image output device for reproducing a viewable real-time image, the improvement wherein a position sensor associated with the image capture device senses position relative to the end effector and a processor transforms the viewable real-time image into a perspective image with correlated manipulation of the end effector by the hand controller such that the operator can manipulate the end effector and the manipulator as if viewing the workspace in true presence. Image transformation according to the invention includes translation, rotation and perspective correction. |
| FILED | Tuesday, April 15, 2003 |
| APPL NO | 10/414814 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333896 | Hitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Correlogic Systems, Inc. (Rockville, Maryland); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Ben A. Hitt (Gaithersburg, Maryland); Peter J. Levine (Potomac, Maryland); Emanuel F. Petricoin, III (Dunkirk, Maryland) |
| ABSTRACT | The present invention relates to a method of quality assurance/quality control for high-throughput bioassay processes. The method includes generating a bioassay process model, and then comparing spectral data based on a combination of a biochip and a test serum to the bioassay process model to determine if the test sample and the bioassay process are producing acceptable data. Alternatively, the method may include comparing spectral data based on a combination of serum and diluents used in an electrospray process to the bioassay process model. If the bioassay process and test sample fall within the model, then the spectrum produced may be further analyzed. |
| FILED | Monday, July 28, 2003 |
| APPL NO | 10/628137 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07331183 | Askew |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gregory K. Askew (Saint Inigoes, Maryland) |
| ABSTRACT | A personal portable environmental control system, which includes a thermoelectric device, two heat sinks, an exhaust fan for blowing ambient air across one heat sink and a blower for blowing ambient air across the other heat sink such that the blown air is conditioned (either heated or cooled). The thermoelectric device is disposed between the two heat sinks. |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/250710 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Refrigeration 062/3.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331268 | Pangilinan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gerardo I. Pangilinan (Alexandria, Virginia); Thomas P. Russell (Manasses, Virginia); Von H. Whitley (Washington, District of Columbia) |
| ABSTRACT | A method for neutralizing explosive ordnance is provided. According to an aspect of the method, an energetic charge is activated to produce a shockwave, which is imparted at an effective velocity and temperature on a gas to ionize the gas for creating plasma and to drive the plasma. The plasma is impacted on a casing of an ordnance containing an explosive to penetrate through the casing and, without or before causing an explosive event of explosive within the casing, substantially consume the explosive. |
| FILED | Wednesday, June 02, 2004 |
| APPL NO | 10/863842 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosive-charge making 086/50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331292 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven S. Kim (Crofton, Maryland); Eric Hawley (Prince Frederick, Maryland); Joni Johnson (La Plata, Maryland); Matt Nolder (Indian Head, Maryland); John Luense (Accokeek, Maryland) |
| ABSTRACT | An ordnance venting system has one or more adapters that separate the warhead section from other sections of a rocket, or submunition compartments within the warhead itself. The adapters structurally fail at given temperatures and pressures to reduce the danger of explosion from heat induced over-pressurization. By dividing the sections of the rocket with the adapters, the separate sections of the rocket become physically separated by the structural failure of the adapters. |
| FILED | Tuesday, March 23, 2004 |
| APPL NO | 10/807581 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/481 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331612 | Frost et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Cristopher Frost (Scottsdale, Arizona); Richard D. Kocher (Tempe, Arizona) |
| ABSTRACT | A low profile tension style flexible joint for pneumatic ducting may be useful as, for example, a joint for aircraft engine pneumatic ducting. The joint of the present invention may be used at both ends of a duct that passes high temperature (up to about 1200° F.) and high pressure (up to about 110 psia) compressor air to the combustor of a turbomachine. Some turbomachines, such as the turbo engine of a jet-powered aircraft, require a very short curved duct to fit into an unusually small aircraft installation envelope. Moreover, these installations also require those features found in conventional flex joints, including being able to support the axial load inherent in pressurized ducting systems. Unlike conventional flexible joints, such as ball joints, gimble joints and pressure compensated joints, the low profile tension style flexible joint of the present invention provides a low profile, low weight design with the ability to support the axial load inherent in pressurized ducting systems. |
| FILED | Friday, March 26, 2004 |
| APPL NO | 10/810456 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipe joints or couplings 285/92 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331669 | Elsner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Bloomington, Indiana) |
| INVENTOR(S) | Ann E. Elsner (Reading, Massachusetts) |
| ABSTRACT | A portable, lightweight digital imaging device uses a slit scanning arrangement to obtain an image of the eye, in particular the retina. The scanning arrangement reduces the amount of target area illuminated at a time, thereby reducing the amount of unwanted light scatter and providing a higher contrast image. A detection arrangement receives the light remitted from the retinal plane and produces an image. The device is operable under battery power and ambient light conditions, such as outdoor or room lighting. The device is noncontact and does not require that the pupil of the eye be dilated with drops. The device can be used by personnel who do not have specialized training in the eye, such as emergency personnel, pediatricians, or general practitioners. Images can be viewed in the device or transmitted to a remote location. The device can also be used to provide images of the anterior segment of the eye or other small structures. |
| FILED | Wednesday, October 16, 2002 |
| APPL NO | 10/493044 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331713 | Moyers |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
| INVENTOR(S) | Michael F. Moyers (Colton, California) |
| ABSTRACT | A device 10 for aligning a patient for delivering a plurality of radiation beams comprising a patient support surface 12, a coarse alignment subsystem 14 connected to the patient support surface, and a fine alignment subsystem connected to the patient support surface 16. A method of aligning a patient for delivering a plurality of radiation beams from a plurality of device positions comprising compensating for flexion of a radiation beam delivery device within a gantry during movement of the radiation beam delivery device from a first device position to a second device position by using a set of predetermined data describing the flexion behavior of the radiation beam delivery device so that the target tissue within the patient is placed at the beamline center for the radiation beam delivery device at the second device position. |
| FILED | Wednesday, December 21, 2005 |
| APPL NO | 11/314138 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/205 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331795 | Duke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Quach Duke (San Gabriel, California) |
| ABSTRACT | Provided is an electrical connector for interconnecting electrical components such as a printed wiring assembly to one or more additional printed wiring assemblies. The connector includes a housing containing one or more compliant pins, one or more spring probes, and an interconnect for mechanically and electrically interfacing the pins with the probes. An alignment pin mounted in the housing helps to ensure alignment between one end of the connector and a corresponding PWA. In use, the compliant pins are inserted through a conformal coating and into vias in a first PWA, while the spring probes contact connector pads on a second PWA. Multiple connectors may be used to interconnect the two PWA, depending on PWA design. |
| FILED | Friday, January 13, 2006 |
| APPL NO | 11/331634 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/66 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331796 | Hougham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Gareth G. Hougham (Ossining, New York); Brian S. Beaman (Cary, North Carolina); Evan G. Colgan (Chestnut Ridge, New York); Paul W. Coteus (Yorktown, New York); Stefano S. Oggioni (Besana in Brianza, Italy); Enrique Vargas (Bronx, New York) |
| ABSTRACT | A land grid array (LGA) interposer structure, including an electrically insulating carrier plane, and at least one interposer mounted on a first surface of said carrier plane. The interposer possesses a hemi-toroidal configuration in transverse cross-section and is constituted of a dielectric elastomeric material. A plurality of electrically-conductive elements are arranged about the surface of the at least one hemi-toroidal interposer and extend radically inwardly and downwardly from an uppermost end thereof into electrical contact with at least one component located on an opposite side of the electrically insulating carrier plane. Provided is also a method of producing the land grid array interposer structure. |
| FILED | Wednesday, March 01, 2006 |
| APPL NO | 11/365366 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/66 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332048 | Navarro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Julio Navarro (Kent, Washington); Richard N Bostwick (North Bend, Washington); Mark S Bolster (Fall City, Washington) |
| ABSTRACT | An apparatus and method for forming and bonding of flexible circuits to metal structures includes a clamping frame having a removable frame portion. At least one flexible roller fixture provides opposed flexible rollers. A clearance aperture in the roller fixture is sized to slidably receive the clamping frame. As the clamping frame is inserted through the clearance aperture of the roller fixture the opposed flexible rollers apply a continuous pressure to deflect the flexible circuit. A curing clamp is then connected to the clamping frame having at least one engagement face defining a flexible circuit finished shape. The flexible circuit is then heat cured to adhesively bond to the metal structure. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/991291 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/212 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332101 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Harpreet Singh (Cambridge, Massachusetts); T. Alan Hatton (Sudbury, Massachusetts) |
| ABSTRACT | One aspect of the present invention relates to a permanently linked, rigid, magnetic chain of particles prepared by sol-gel methods. A second aspect of the present invention relates to a method of preparing a permanently linked, rigid, magnetic chain of particles comprising: coating a core material with one or more polyelectrolyte layers resulting in a coated particle; further coating the coated particle with a layer of magnetic nanoparticles resulting in a magnetic particle; coating the magnetic particle with a layer of a polycationic polyelectrolyte resulting in a coated magnetic particle; and applying a magnetic field to the coated magnetic particle in the presence of a metal oxide or metal oxide precursor capable of undergoing hydrolysis. |
| FILED | Friday, June 25, 2004 |
| APPL NO | 10/877051 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions 252/62.51R |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332112 | Shivakumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | N.C. A and T State University (Greensboro, North Carolina) |
| INVENTOR(S) | Kunigal N. Shivakumar (Greensboro, North Carolina); Vishnu Sarma Avva (Greensboro, North Carolina); Mannur J. Sundaresan (Greensboro, North Carolina); Felix Abali (Greensboro, North Carolina); Anthony Cunningham (Greensboro, North Carolina); Robert L. Sadler (Greensboro, North Carolina) |
| ABSTRACT | An apparatus and method for forming a densified carbon-carbon composite. The apparatus includes: a green part molding station for forming a green part; a carbonization station for carbonizing the green part; and an impregnation station for impregnating the carbonized part with a substantially curing by-product free, high carbon yield resin. The impregnation station includes a mold forming a sealed enclosure configured in the shape of the carbonized part for receiving the carbonized part and a vacuum source for evacuating the mold. At least one resin injection port is in the mold and a supply of substantially curing by-product free, high carbon yield resin is connected to the resin injection port for injection into the mold. In the preferred embodiment, the substantially curing by-product free, high carbon yield resin is a cyanate ester having a viscosity of less than about 100 cps at 250° F. and a carbon yield value of greater than about 60 wt. %. The combination of a high carbon yield resin and a pressurized impregnation station configured to the shape of the composite part for use with a curing by-product free resin provides for a substantial reduction in the number of carbonization cycles required to reach final density while, at the same time avoids the environmental and safety problems of a solvent-based system. |
| FILED | Monday, May 24, 2004 |
| APPL NO | 10/852293 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/29.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332172 | Wolf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Marcia Kay Wolf (Silver Spring, Maryland); Frederick J. Cassels (Laurel, Maryland); Edgar Charles Boedeker (Crownsville, Maryland) |
| ABSTRACT | Disclosed herein are antigens that stimulate protective antibodies against enterotoxigenic Escherichia coli. Also disclosed herein are proteins encoded by cssA and cssB genes as well as constructs containing the genes and methods of using thereof. |
| FILED | Monday, February 02, 2004 |
| APPL NO | 10/768093 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/241.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332218 | Gilbert |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | EIC Laboratories, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Michael D. Gilbert (Brookline, New Hampshire) |
| ABSTRACT | An electrochemically disbondable composition is provided having a matrix functionality and an electrolyte functionality. The matrix functionality provides an adhesive bond to a substrate, and the electrolyte functionality provides sufficient ionic conductivity to the composition to support a faradaic reaction at an interface with an electrically conductive surface in contact with the composition, whereby the adhesive bond is weakened at the interface. The composition may be a phase-separated composition having first regions of substantially matrix functionality and second regions of substantially electrolyte functionality. Adhesive and coating compositions and methods of disbonding also are described. |
| FILED | Wednesday, July 14, 1999 |
| APPL NO | 09/352976 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332249 | Cetin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Aprilis, Inc. (Maynard, Massachusetts) |
| INVENTOR(S) | Erdem A. Cetin (Waltham, Massachusetts); Richard A. Minns (Arlington, Massachusetts); David A. Waldman (Concord, Massachusetts) |
| ABSTRACT | Disclosed is a holographic recording medium. The novel holographic recording mediums disclosed herein comprises: a) at least one polyfunctional epoxide monomer or oligomer which undergoes acid initiated cationic polymerization. Each epoxide in the monomer or oligomer is linked by group comprising a siloxane to a silicon atom and each monomer or oligomer has an epoxy equivalent weight of greater than about 300 grams/mole epoxide; b) a binder which is capable of supporting cationic polymerization; c) an acid generator capable of producing an acid upon exposure to actinic radiation; and optionally d) a sensitizer. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385979 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332290 | Rubin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Mark A. Rubin (Newton, Massachusetts); Arul M. Chinnaiyan (Plymouth, Michigan); Bharathi Laxman (Ann Arbor, Michigan); Arun Sreekumar (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. The present invention also provides novel markers useful for the diagnosis, characterization, and treatment of prostate cancers. In particular, the present invention provides methods and compositions for the detection of α-methylacyl-CoA racemase (AMACR) in the urine as a marker for prostate cancer detection. |
| FILED | Friday, July 30, 2004 |
| APPL NO | 10/909035 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332297 | Samuelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lynne A. Samuelson (Marlborough, Massachusetts); Ferdinando Bruno (Andover, Massachusetts); Susan Tripathy, legal representative (Acton, Massachusetts); Ramaswamy Nagarajan (Lowell, Massachusetts); Jayant Kumar (Westford, Massachusetts); Wei Liu (Lowell, Massachusetts) |
| ABSTRACT | The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction mixture for a time and under conditions sufficient for the monomer to align along the template and polymerize to form a polymer-template complex. The template can be a micelle, a borate-containing electrolyte, or lignin sulfonate. Such a complex possesses exceptional electrical and optical stability, water solubility, and processibility, and can be used in applications such as light-weight energy storage devices (e.g., rechargeable batteries), electrolytic capacitors, anti-static and anti-corrosive coatings for smart windows, and biological sensors. |
| FILED | Friday, March 14, 2003 |
| APPL NO | 10/390676 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332321 | Belcher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Angela M. Belcher (Lexington, Massachusetts); Seung-Wuk Lee (Cambridge, Massachusetts) |
| ABSTRACT | Long rod shaped M13 viruses were used to fabricate one dimensional (1D) micro- and nanosized diameter fibers by mimic the spinning process of the silk spider. Liquid crystalline virus suspensions were extruded through the micrometer diameter capillary tubes in cross-linking solution (glutaraldehyde). Resulting fibers were tens of micrometers in diameter depending on the inner diameter of the capillary tip. AFM image verified that molecular long axis of the virus fibers were parallel to the fiber long axis. Although aqueous M13 virus suspension could not be spun by electrospinning, M13 viruses suspended in 1,1,1,3,3,3-hexafluoro-2-propanol were spun into fibers. After blending with highly water soluble polymer, polyvinyl 2-pyrolidone (PVP), M13 viruses was spun into continuous uniform virus blended PVP (virus-PVP) fibers. Resulting virus-PVP electrospun fibers showed intact infecting ability to bacterial hosts after suspending in the buffer solution. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/965665 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332351 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Florida (Gainesville, Florida) |
| INVENTOR(S) | Weihong Tan (Gainesville, Florida); Swadeshmukul Santra (Gainesville, Florida); Peng Zhang (Clearwater, Florida); Rovelyn Tapec (Gainesville, Florida); Jon Dobson (Stoke-on-Trent, United Kingdom) |
| ABSTRACT | Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications. |
| FILED | Monday, July 25, 2005 |
| APPL NO | 11/188459 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/524 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332580 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gregory P. Adams (Philadelphia, Pennsylvania); Eva M. Horak (Philadelphia, Pennsylvania); Louis M. Weiner (Philadelphia, Pennsylvania); James D. Marks (Kensington, California) |
| ABSTRACT | Bispecific single chain antibody molecules are disclosed which may be used to advantage to treat various forms of cancer associated with the overexpression of members of the EGFR protein family. |
| FILED | Friday, April 04, 2003 |
| APPL NO | 10/406830 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332585 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the California University (Oakland, California); Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gregory P. Adams (Hatboro, Pennsylvania); Eva M. Horak (West Orange, New Jersey); Louis M. Weiner (Philadelphia, Pennsylvania); James D. Marks (Kensington, California) |
| ABSTRACT | Bispecific single chain antibody molecules are disclosed which may be used to advantage to treat various forms of cancer associated with the overexpression of members of the EGFR protein family. |
| FILED | Wednesday, June 15, 2005 |
| APPL NO | 11/154103 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332609 | Emrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Todd S. Emrick (South Deerfield, Massachusetts); Kurt Breitenkamp (Northampton, Massachusetts) |
| ABSTRACT | Amphiphilic Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies. |
| FILED | Thursday, October 20, 2005 |
| APPL NO | 11/254947 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332825 | Annen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Aerodyne Research, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Kurt D. Annen (Rowely, Massachusetts); Jaime Woodroffe (North Reading, Massachusetts); Roger Putnam (Newton Highlands, Massachusetts) |
| ABSTRACT | This invention overcomes the disadvantages of the prior art by providing a power generating system particularly suitable for field use in remote locations, which is fuel-efficient, relatively quiet, tolerant of dust, capable of operating on low grade logistics and diesel-like fuels and capable of generating between 500 W and 2 KW of continuous electrical power. This generating system employs a two-cycle MICE generator having a piston that operates within a cylinder, and an interconnected, axially moving piston shaft that oscillates an alternator coil within a magnetic core. The piston shaft is attached to, and resisted by, the free end of a strong spring with a second, opposing end fixed to the MICE casing. To control operation of the MICE generator a dual clipper circuit is operatively connected with the alternator coil. The clipper circuit senses the current and at least two voltage levels and applies at least two respective loads in response to the sensed voltage levels and current so as to (a) prevent overstroke of the piston and (b) control power output of the alternator coil. The MICE generator also includes a fuel intake preheater that selectively heats fuel/air mixture entering the casing and a controller that senses load on the alternator coil varies a level of preheating to thereby control a level of power output. |
| FILED | Friday, January 06, 2006 |
| APPL NO | 11/327732 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Prime-mover dynamo plants 290/1.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332919 | Ho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Ronald Ho (Mountain View, California); Robert J. Drost (Mountain View, California); Arthur R. Zingher (Mountain View, California) |
| ABSTRACT | One embodiment of the present invention provides a system for distributing signals through a jig-plate in a computer system. The jig-plate contains alignment features that assist in positioning semiconductor chips in relation to the jig-plate. In addition, the jig-plate contains one or more embedded signal routing layers. These metal routing layers provide one or more signal routes for the distribution of signals through the jig-plate to semiconductor chips which have been aligned with the jig-plate. Note that routing the signals through the jig-plate facilitates the distribution of the signals without requiring that the signals be routed through the semiconductor chips in the jig-plate. |
| FILED | Wednesday, September 21, 2005 |
| APPL NO | 11/232843 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Measuring and testing 324/754 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333044 | Sandlin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Destin W. Sandlin (Decatur, Alabama) |
| ABSTRACT | A rocket tube for housing a reloadable rocket motor is connected to a spacer element and a wire-rider element. A sensor target for reflecting radar signals is screwably attached to the rocket tube. The sensor target is provided with a plug for effectively sealing one end of the rocket tube with the other end of the rocket tube being utilized to reload a rocket motor upon completion of a test firing. A guide wire is threaded through the wire-rider element with the guide wire serving as a travel path. The rocket tube, spacer element, and wire-rider element are connected in an easily assembled, aerodynamic manner that allows for multiple radar tests using the same components within a brief time period. |
| FILED | Monday, September 25, 2006 |
| APPL NO | 11/534834 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333209 | Greening et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Thomas C. Greening (Peoria, Arizona); Charles H. Lange (Glendale, Arizona); Chung-Jen Chen (Phoenix, Arizona) |
| ABSTRACT | A clock system for a fiber optic gyroscope is provided that includes a highly-tunable clock for the bias modulation and a separate asynchronous high-speed clock for the photodetector sampling. By separating the two clocks rather than using two derivatives of the same clock, the clock system and method can provide both the tunability objective of the bias modulation clock and the high-speed objective of the sampling clock, while using readily available, lower performance, radiation-hardened electronics parts. |
| FILED | Wednesday, November 09, 2005 |
| APPL NO | 11/271994 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/464 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333257 | Reynolds et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | John R. Reynolds (Gainesville, Florida); Avni A. Argun (Gainesville, Florida); Pierre Henri Aubert (Port sur Saone, France); Mathieu Berard (St. Mathurin sur Loire, France) |
| ABSTRACT | A method for contacting patterned electrode devices includes the steps of providing a porous substrate, depositing electrically conductive material to form at least one electrode on a front-side of the porous substrate and depositing at least one electrically conductive back-side contact trace on the back-side of the substrate. A portion of the electrically conductive material penetrates into the substrate. A device is formed including the electrode on the front side of the substrate, wherein the electrode is electrically coupled by a conducting channel including the electrically conductive material through the substrate to the back-side contact trace. |
| FILED | Friday, November 19, 2004 |
| APPL NO | 10/992827 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/265 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333444 | Sharapov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Ilya A. Sharapov (Sunnyvale, California) |
| ABSTRACT | One embodiment of the present invention provides a system for generating an interconnection network. During operation, the system associates an n-bit binary identifier with each node in the interconnection network. The system also groups the n bits of each binary identifier into h overlapping sets a1, a2, . . . ah, wherein the sets a1, a2, . . . ah cover all of the n bits. For each set ai, the system forms fully connected clusters of nodes by creating a direct point-to-point link between any two nodes that have binary identifiers that differ in bits of the set a1 but are the same in other bit positions. Note that by varying the amount of overlap and the pattern of overlap between the overlapping sets, a1, a2, . . . ah, the interconnection network can be configured to accommodate different redundancy requirements. |
| FILED | Wednesday, December 17, 2003 |
| APPL NO | 10/739475 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Multiplex communications 370/255 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333458 | Cain |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Harris Corporation (Melbourne, Florida) |
| INVENTOR(S) | Joseph Bibb Cain (Indialantic, Florida) |
| ABSTRACT | A wireless communication network may include a plurality of mobile nodes each including at least one wireless transceiver, a directional antenna and an omni-directional antenna connected to the at least one wireless transceiver, and a controller for controlling the at least one wireless transceiver. The controller may also be for controlling the at least one wireless transceiver, establishing an omni-directional communication link with another mobile node, and determining a link quality value for the omni-directional communication link. The controller may also establish a directional communication link with the other mobile node if the link quality value for the omni-directional communication link is greater than a quality threshold. |
| FILED | Thursday, March 27, 2003 |
| APPL NO | 10/400998 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Multiplex communications 370/337 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333611 | Yuen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Horace P. Yuen (Glenview, Illinois); Prem Kumar (Skokie, Illinois); Geraldo A. Barbosa (Franklin, Tennessee) |
| ABSTRACT | A method and system for achieving the cryptographic objectives of data encryption and/or key expansion/generation by utilizing a short, shared, secret seed key between two parties that is extended to a long extended key which, in turn, is used to select one of many possible quantum and/or classical signal sets. The signal strength of each signal in the signal set is adjusted in accordance with the number of signal sets to obtain the necessary security level. The system operates with whatever signal quantum noise and other system noises are present while preserving security of the cryptographic system. The signal quantum noise and system noises protect both the data and the key from attackers. |
| FILED | Monday, September 29, 2003 |
| APPL NO | 10/674241 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Cryptography 380/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333647 | Boas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David A. Boas (New Market, New Hampshire); Quan Zhang (Somerville, Massachusetts); Ang Li (Somerville, Massachusetts) |
| ABSTRACT | A system for obtaining a resultant image and a method to utilize the same are provided. In particular, first and second images of a subject or a portion of the subject are obtained. The first image includes a first portion of the subject and a second portion of the subject, and each of the first image and the second image are different types of images. A first probability that the first portion has a contrast which is greater than a predetermined contrast and a second probability that the second portion has a contrast which is greater than the predetermined contrast then is determined using the second image. For example, the second probability is greater than the first probability. Moreover, the first and second portions of the first image are reconstructed to generate the resultant image. Specifically, the first portion is reconstructed based on the first probability and the second portion is reconstructed based on the second probability. |
| FILED | Thursday, April 03, 2003 |
| APPL NO | 10/406751 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333689 | Menon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Vinod M. Menon (Lawrenceville, New Jersey); Milind R. Gokhale (Princeton, New Jersey); Stephen R. Forrest (Princeton, New Jersey); Yu Huang (Princeton, New Jersey); Fengnian Xia (Plainsboro, New Jersey) |
| ABSTRACT | An asymmetric twin waveguide (ATG) structure with quantum-well intermixing in the taper region of the active waveguide is disclosed. The structure comprises a first waveguide, a second waveguide, and a taper formed in the second waveguide. The taper has an intermixed area formed therein comprising a plurality of quantum wells intermixed with a plurality of barriers. The quantum wells and barriers may be intermixed using plasma-enhanced intermixing such as, for example, Argon plasma enhanced intermixing. Quantum-well intermixing reduces absorption loss normally encountered in the movement of light between waveguides. |
| FILED | Friday, September 30, 2005 |
| APPL NO | 11/241003 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333691 | Gill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Douglas M. Gill (South Orange, New Jersey); Sanjay Patel (New Providence, New Jersey); Mahmoud Rasras (New Providence, New Jersey) |
| ABSTRACT | An apparatus, including an optical ring resonator having a waveguide ring with substantially straight waveguide segments and bent waveguide segments. The bent waveguide segments are optically coupled to the substantially straight waveguide segments and have optical cores with substantially smaller cross-sectional areas than the substantially straight waveguide segments. The bent waveguide segments change a propagation direction of received light by more than ½ of a right angle. |
| FILED | Friday, December 29, 2006 |
| APPL NO | 11/618349 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07331714 | Shu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Deming Shu (Darien, Illinois); Jorg M. Maser (Oak Park, Illinois); Barry Lai (Woodridge, Illinois); Franz Stefan Vogt (Plainfield, Illinois); Martin V. Holt (Chicago, Illinois); Curt A. Preissner (Rosemont, Illinois); Robert P. Winarski (Lockport, Illinois); Gregory B. Stephenson (Lisle, Illinois) |
| ABSTRACT | A multifunctional hard x-ray nanoprobe instrument for characterization of nanoscale materials and devices includes a scanning probe mode with a full field transmission mode. The scanning probe mode provides fluorescence spectroscopy and diffraction contrast imaging. The full field transmission mode allows two-dimensional (2-D) imaging and tomography. The nanoprobe instrument includes zone plate optics for focusing and imaging. The nanoprobe instrument includes a stage group for positioning the zone plate optics. The nanoprobe instrument includes a specimen stage group for positioning the specimen. An enhanced laser Doppler displacement meter (LDDM) system provides two-dimensional differential displacement measurement in a range of nanometer resolution between the zone-plate optics and the sample holder. A digital signal processor (DSP) implements a real-time closed-loop feedback technique for providing differential vibration control between the zone-plate optics and the sample holder. |
| FILED | Thursday, September 29, 2005 |
| APPL NO | 11/238196 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/208 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07331803 | Steigerwald et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Robert Louis Steigerwald (Burnt Hills, New York); Todd Alan Anderson (Niskayuna, New York) |
| ABSTRACT | A power system includes an energy harvesting device, a battery coupled to the energy harvesting device, and a circuit coupled to the energy harvesting device and the battery. The circuit is adapted to deliver power to a load by providing power generated by the energy harvesting device to the load without delivering excess power to the battery and to supplement the power generated by the energy harvesting device with power from the battery if the power generated by the energy harvesting device is insufficient to fully power the load. A method of operating the power system is also provided. |
| FILED | Tuesday, October 17, 2006 |
| APPL NO | 11/582236 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332200 | Soukos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Nikolaos S. Soukos (Revere, Massachusetts); Shun Lee (Arlington, Virginia); Apostolos G. Doukas (Belmont, Massachusetts) |
| ABSTRACT | Methods for permeabilizing biofilms using stress waves are described. The methods involve applying one or more stress waves to a biofilm, e.g., on a surface of a device or food item, or on a tissue surface in a patient, and then inducing stress waves to create transient increases in the permeability of the biofilm. The increased permeability facilitates delivery of compounds, such as antimicrobial or therapeutic agents into and through the biofilm. |
| FILED | Friday, May 12, 2000 |
| APPL NO | 10/019837 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/554 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332222 | Luzzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | David E. Luzzi (Wallingford, Pennsylvania); Brian W. Smith (Philadelphia, Pennsylvania) |
| ABSTRACT | A hybrid material is provided which comprises a first single-walled nanotube having a lumen, and a fill molecule contained within the lumen of the single-walled nanotube. A method for producing the hybrid material is also provided wherein a single-walled nanotube is contacted with a fill molecule to cause the fill molecule to enter the lumen of the single-walled nanotube. |
| FILED | Monday, March 07, 2005 |
| APPL NO | 11/074222 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/408 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332264 | Doshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Dhaval Doshi (Los Alamos, New Mexico); Hongyou Fan (Albuquerque, New Mexico); Nicola Huesing (Vienna, Austria); Alan Hurd (Tijeras, New Mexico); Charles Jeffrey Brinker (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides a mesoporous material comprising at least one region of mesoporous material patterned at a lithographic scale. The present invention also provides a method for forming a patterned mesoporous material comprising: coating a sol on a substrate to form a film, the sol comprising: at least one photoactivator generator, at least one material capable of being sol-gel processed; and exposing the film to light to form a patterned mesoporous material. |
| FILED | Wednesday, February 26, 2003 |
| APPL NO | 10/373565 |
| ART UNIT | 1756 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332283 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yi Lu (Champaign, Illinois); Juewen Liu (Urbana, Illinois) |
| ABSTRACT | A novel biosensor comprises at least one fluorophore and at least two quenchers, and is capable of selectively and specifically detecting the presence of an ion in the presence of other ions. |
| FILED | Wednesday, March 16, 2005 |
| APPL NO | 11/082197 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332599 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Lianhe Yu (Raleigh, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Prathapan Sreedharan (Kerala, India); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | The present invention provides dipyrrin substituted porphyrinic macrocycles, intermediates useful for making the same, and methods of making the same. Such compounds may be used for purposes including the making of molecular memory devices, solar cells and light harvesting arrays. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/456321 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332609 | Emrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Todd S. Emrick (South Deerfield, Massachusetts); Kurt Breitenkamp (Northampton, Massachusetts) |
| ABSTRACT | Amphiphilic Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies. |
| FILED | Thursday, October 20, 2005 |
| APPL NO | 11/254947 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332722 | Tran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Jefferson Science Associates, LLC (Newport News, Virginia) |
| INVENTOR(S) | Vi-Hoa Tran (Newport News, Virginia); Steven Richard Meikle (Penshurst, Australia); Mark Frederick Smith (Yorktown, Virginia) |
| ABSTRACT | A method for calibrating multi-headed high sensitivity and high spatial resolution dynamic imaging systems, especially those useful in the acquisition of tomographic images of small animals. The method of the present invention comprises: simultaneously calibrating two or more detectors to the same coordinate system; and functionally correcting for unwanted detector movement due to gantry flexing. |
| FILED | Tuesday, February 21, 2006 |
| APPL NO | 11/358270 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/363.90 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333205 | Bouhelier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | U Chicago Argonne LLC (Chicago, Illinois) |
| INVENTOR(S) | Alexandre Bouhelier (Westmont, Illinois); Gary P. Wiederrecht (Elmhurst, Illinois) |
| ABSTRACT | A system and method for generating and using broadband surface plasmons in a metal film for characterization of analyte on or near the metal film. The surface plasmons interact with the analyte and generate leakage radiation which has spectral features which can be used to inspect, identify and characterize the analyte. The broadband plasmon excitation enables high-bandwidth photonic applications. |
| FILED | Monday, September 19, 2005 |
| APPL NO | 11/230281 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333309 | Tekletsadik |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | SuperPower, Inc (, None) |
| INVENTOR(S) | Kasegn D. Tekletsadik (Rexford, New York) |
| ABSTRACT | A superconducting fault current limiter array with a plurality of superconductor elements arranged in a meanding array having an even number of supconductors parallel to each other and arranged in a plane that is parallel to an odd number of the plurality of superconductors, where the odd number of supconductors are parallel to each other and arranged in a plane that is parallel to the even number of the plurality of superconductors, when viewed from a top view. The even number of superconductors are coupled at the upper end to the upper end of the odd number of superconductors. A plurality of lower shunt coils each coupled to the lower end of each of the even number of superconductors and a plurality of upper shunt coils each coupled to the upper end of each of the odd number of superconductors so as to generate a generally orthoganal uniform magnetic field during quenching using only the magenetic field generated by the superconductors. |
| FILED | Thursday, May 18, 2006 |
| APPL NO | 11/436869 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07332211 | Bulovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vladimir Bulovic (Lexington, Massachusetts); Seth A. Coe (Watertown, Massachusetts); Wing-Keung Woo (Cambridge, Massachusetts); Moungi G. Bawendi (Boston, Massachusetts) |
| ABSTRACT | A composition includes a layer of nanoparticles and a layer of a second material. |
| FILED | Friday, March 28, 2003 |
| APPL NO | 10/400907 |
| ART UNIT | 1775 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332222 | Luzzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | David E. Luzzi (Wallingford, Pennsylvania); Brian W. Smith (Philadelphia, Pennsylvania) |
| ABSTRACT | A hybrid material is provided which comprises a first single-walled nanotube having a lumen, and a fill molecule contained within the lumen of the single-walled nanotube. A method for producing the hybrid material is also provided wherein a single-walled nanotube is contacted with a fill molecule to cause the fill molecule to enter the lumen of the single-walled nanotube. |
| FILED | Monday, March 07, 2005 |
| APPL NO | 11/074222 |
| ART UNIT | 1775 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/408 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332351 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Florida (Gainesville, Florida) |
| INVENTOR(S) | Weihong Tan (Gainesville, Florida); Swadeshmukul Santra (Gainesville, Florida); Peng Zhang (Clearwater, Florida); Rovelyn Tapec (Gainesville, Florida); Jon Dobson (Stoke-on-Trent, United Kingdom) |
| ABSTRACT | Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reactive silicate is added to coat the cores with silica. Also disclosed are methods for functionalizing silica-coated nanoparticles for use in a variety of applications. |
| FILED | Monday, July 25, 2005 |
| APPL NO | 11/188459 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/524 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332355 | Hsieh-Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Linda Hsieh-Wilson (San Marino, California); Nelly Khidekel (Pasadena, California); Hwan-Ching Tai (Pasadena, California); Sabine Arndt (Dortmund, Germany) |
| ABSTRACT | The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations. The methods can be used to detect O-GlcNAc post-translational modifications on proteins on which such modifications were undetectable using other techniques. In one embodiment, the method exploits the ability of an engineered mutant of β-1,4-galactosyltransferase to selectively transfer an unnatural ketone functionality onto O-GlcNAc glycosylated proteins. Once transferred, the ketone moiety serves as a versatile handle for the attachment of biotin, thereby enabling detection of the modified protein. The approach permits the rapid visualization of proteins that are at the limits of detection using traditional methods. Further, the preferred embodiments can be used for detection of certain disease states, such as cancer, Alzheimer's disease, neurodegeneration, cardiovascular disease, and diabetes. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/990767 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332586 | Franzen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Stefan Franzen (Apex, North Carolina); Daniel L. Feldheim (Cary, North Carolina); Alexander G. Tkachenko (Raleigh, North Carolina); Marisha L. Godek (Fort Collins, Colorado); Joseph A. Ryan (Raleigh, North Carolina); Stefan Franzen, legal representative (Apex, North Carolina) |
| ABSTRACT | A nanoparticle delivery vehicle, comprising a nanoparticle, an active agent and a nuclear localization signal and methods of modulating gene expression and protein expression employing the nanoparticle delivery vehicle. A representative method includes providing a nanoparticle delivery vehicle comprising a nanoparticle having a diameter of about 30 nm or less, an active agent and a nuclear localization signal; and contacting a target cell with the nanoparticle delivery vehicle, whereby an active agent is delivered to the nucleus of a target cell. Another representative method includes providing a nanoparticle delivery vehicle comprising a nanoparticle having a diameter greater than or equal to about 30 nm, an active agent and a nuclear localization signal; and contacting a target cell with the nanoparticle delivery vehicle, whereby an active agent is delivered to the cytoplasm of a cell. |
| FILED | Wednesday, July 10, 2002 |
| APPL NO | 10/192393 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332705 | Saggau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas); Wiliam Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Peter Saggau (Houston, Texas); Duemani Reddy (Houston, Texas); Vijay Iyer (Huntington, New York) |
| ABSTRACT | A system and method for independently controlling the collimation and lateral positioning of a light beam comprises at least one acousto-optic deflector and a pair of counter propagating acoustic waves with offset frequencies. While the frequency offset controls the lateral positioning of the light beam, a frequency gradient across the acousto-optic deflectors controls the collimation of the light beam. |
| FILED | Tuesday, February 20, 2007 |
| APPL NO | 11/676924 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333622 | Algazi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | V. Ralph Algazi (Davis, California); Richard O. Duda (Menlo Park, California); Dennis Thompson (Davis, California) |
| ABSTRACT | A new approach to capturing and reproducing either live or recorded three-dimensional sound is described. Called MTB for “Motion-Tracked Binaural,” the method employs several microphones, a head tracker, and special signal-processing procedures to combine the signals picked up by the microphones. MTB achieves a high degree of realism by effectively placing the listener's ears in the space where the sounds are occurring, moving the virtual ears in synchrony with the listener's head motions. MTB also provides a universal format for recording spatial sound. |
| FILED | Tuesday, April 15, 2003 |
| APPL NO | 10/414261 |
| ART UNIT | 2615 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electrical audio signal processing systems and devices 381/310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333850 | Marossero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Convergent Engineering, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Dorothee Marossero (Gainesville, Florida); Tammy Y. Euliano (Gainesville, Florida); Neil Russell Euliano, II (Gainesville, Florida); Jose C. Principe (Gainesville, Florida) |
| ABSTRACT | A maternal-fetal monitoring system for use during all stages of pregnancy, including antepartum and intrapartum stages. The maternal-fetal monitoring system of the subject invention comprises (1) a set of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, maternal electrocardiogram (ECG) signals, maternal uterine activity signals (EHG), maternal heart rate, fetal ECG signals, and fetal heart rate. In a preferred embodiment, the maternal-fetal monitoring system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis antepartum, intrapartum and postpartum, as well as delivery strategy. |
| FILED | Friday, May 28, 2004 |
| APPL NO | 10/857107 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 6/511 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07331381 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Allcomp, Inc. (City of Industry, California) |
| INVENTOR(S) | Jinliang Wang (Los Angeles, California); Wei-Teh Shih (Yorba Linda, California) |
| ABSTRACT | A light weight hybrid heat exchanger core possessing low density and improved thermal conductivity is disclosed. The hybrid core is comprised of a plurality of parting sheets and interposed by a plurality of high thermal conductivity, light weight bridging elements and enclosure bars. These core members are comprised of dissimilar materials. The parting sheets and bridging elements are interconnected by a specially tailored joint which forms form a substantially strong, high thermal conductivity bond. In particular embodiments, carbon-based bridging elements are bonded to metallic parting sheets using a brazed joint. The parting sheets, in certain embodiments, may comprise titanium or Ni-based superalloys or carbon composites, while the carbon-based bridging elements may comprise fiber-reinforced composites. The carbon-based bridging elements reduce the core weight and increase the core thermal conductivity over conventional all-metal designs, while the brazed joint provides for improved leak resistance over all-composite designs. |
| FILED | Thursday, February 16, 2006 |
| APPL NO | 11/356337 |
| ART UNIT | 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Heat exchange 165/166 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332345 | Darrach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Murray R. Darrach (Valencia, California); Ara Chutjian (La Crescenta, California) |
| ABSTRACT | A chemical sensing apparatus and method for the detection of sub parts-per-trillion concentrations of molecules in a sample by optimizing electron utilization in the formation of negative ions is provided. A variety of media may be sampled including air, seawater, dry sediment, or undersea sediment. An electrostatic mirror is used to reduce the kinetic energy of an electron beam to zero or near-zero kinetic energy. |
| FILED | Tuesday, November 12, 2002 |
| APPL NO | 10/293966 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333571 | Simon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Marvin K. Simon (La Canada, California); Dariush Divsalar (Pacific Palisades, California) |
| ABSTRACT | A concatenated coding scheme, using an outer coder, interleaver, and the inner coder inherent in an FQPSK signal to form a coded FQPSK signal. The inner coder is modified to enable interactive decoding of the outer code. |
| FILED | Tuesday, April 23, 2002 |
| APPL NO | 10/131611 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/329 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333735 | Goorjian |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| INVENTOR(S) | Peter M. Goorjian (Oakland, California) |
| ABSTRACT | Ultrafast directional beam switching, using coupled VCSELs is combined with a light modulator to provide information transfer at bit rates of tens of GHz. This approach is demonstrated to achieve beam switching frequencies of 32-50 GHz in some embodiments and directional beam switching with angular differences of about eight degrees. This switching scheme is likely to be useful for ultrafast optical networks at frequencies much higher than achievable with other approaches. A Mach-Zehnder interferometer, a Fabry-Peror etalon, or a semiconductor-based electro-absorption transmission channel, among others, can be used as a light modulator. |
| FILED | Wednesday, June 30, 2004 |
| APPL NO | 10/885533 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/182 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07332170 | Borca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Manuel V. Borca (Westbrook, Connecticut); Guillermo R. Risatti (Westbrook, Connecticut); Daniel L. Rock (Monticello, Illinois) |
| ABSTRACT | Transposon linker insertion mutagenesis of a full-length infectious clone of the highly pathogenic classical swine fever virus (CSFV) isolate Brescia (pBIC) was used to identify genetic determinants of CSFV virulence and host range. A virus mutant, RB-C22 (RB-C22v), possessing a 19-residue tag insertion at the carboxyl end of E1 was constructed. RB-C22v and the parental virus pBIC (pBICv) exhibited similar growth characteristics on primary porcine macrophage cell cultures although RB-C22v produced significantly smaller plaques on SK6 cell cultures. In vivo, RB-C22v was markedly attenuated in swine. In contrast with pBIC infection, where mortality was 100%, all RB-C22v-infected pigs survived infection remaining clinically normal. Additionally, chimeras of the Brescia strain and the attenuated vaccine strain CS were constructed and evaluated for viral virulence in swine. Chimeras 138.8v and 337.14v, chimeras containing the E2 glycoprotein of CS and chimeric virus 319.1v, which contained only the CS E2 glycoprotein in the Brescia background, were attenuated in swine. Chimeras encoding all Brescia structural proteins in a CS genetic background remained attenuated, indicating that additional mutations outside the structural region are important for CS vaccine virus attenuation. The combined results indicate a significant role for E1 glycoprotein and E2 glycoprotein in swine virulence. |
| FILED | Friday, December 23, 2005 |
| APPL NO | 11/316755 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/218.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332176 | Valles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Steven M. Valles (Gainesville, Florida); Roberto M. Pereira (Gainesville, Florida); Wayne B. Hunter (Port St. Lucie, Florida); David H. Oi (Gainesville, Florida); Charles A. Strong (Gainesville, Florida); Phat M. Dang (Port St. Lucie, Florida); David F. Williams (Gainesville, Florida) |
| ABSTRACT | Unique Solenopsis invicta viruses (SINV) have been identified and their genome sequenced. Oligonucleotide primers have been developed using the isolated nucleic acid sequences of the SINV. The viruses are used as a biocontrol agent for control of fire ants. |
| FILED | Thursday, September 29, 2005 |
| APPL NO | 11/239183 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/405 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332592 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Yan Wang (Hyattsville, Maryland); Dante S. Zarlenga (Ellicott City, Maryland); Max J. Paape (Silver Spring, Maryland) |
| ABSTRACT | Studies in mice and humans indicate that membrane CD14 (mCD14) on the cell surface of monocytes, macrophages, and PMN mediates the activation of these cells by LPS. The soluble CD14 (sCD14) present in the circulation also binds to LPS and blocks LPS binding to mCD14. To determine the role of a recombinant bovine soluble CD14 polypeptide in cellular activation by LPS, a recombinant bovine soluble CD14 polypeptide, rbosCD14, was cloned and expressed in a baculovirus expression system. Results indicated that rbosCD14 inhibited the LPS-induced increase in CD18 expression and TNFα mRNA in vitro and reduced mortality in mice injected with LPS. Further, rbosCD14 sensitized mammary epithelial cells to low concentrations of LPS resulting in recruitment of white blood cells and prevention of LPS-induced infection. |
| FILED | Friday, June 03, 2005 |
| APPL NO | 11/144747 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07332280 | Levy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald Levy (Stanford, California); Mark A. Wechser (Foster City, California); Izidore S. Lossos (Miami, Florida); Robert J. Tibshirani (Palo Alto, California); Ash A. Alizadeh (San Mateo, California); David Botstein (Princeton, New Jersey) |
| ABSTRACT | Methods and kits for classifying patients having diffuse large B-cell lymphoma (DLBCL) based upon expression of a plurality of genes are disclosed. Real-time quantitative RT-PCR can be used to measure expression values. Correlating expression values of the plurality of genes in a tumor sample from the patient to reference expression values obtained from DLBCL patients can stratify patients in the classification groups. The methods and kits can be used to predict overall patient survival. |
| FILED | Wednesday, March 03, 2004 |
| APPL NO | 10/792374 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333676 | Myers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Gregory K. Myers (San Francisco, California); Robert C. Bolles (Mountain View, California); Quang-Tuan Luong (Menlo Park, California); James A. Herson (Emerald Hills, California) |
| ABSTRACT | An apparatus and a concomitant method for detecting and recognizing text information in a captured imagery. The present method transforms the image of the text to a normalized coordinate system before performing OCR, thereby yielding more robust recognition performance. The present invention also combines OCR results from multiple frames, in a manner that takes the best recognition results from each frame and forms a single result that can be more accurate than the results from any of the individual frames. |
| FILED | Wednesday, January 11, 2006 |
| APPL NO | 11/330494 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/289 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07334014 | Moser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Availigent, Inc. (San Jose, California) |
| INVENTOR(S) | Louise E. Moser (Santa Barbara, California); Peter M. Melliar-Smith (Santa Barbara, California); Wenbing Zhao (Goleta, California) |
| ABSTRACT | A consistent time service that provides a method of maintaining deterministic clock-related operations for a group of replicas in a fault-tolerant distributed system. A consistent clock synchronization algorithm is utilized that yields a single consistent group clock for the replicas in the group, and does not require synchronization of the underlying physical hardware clocks. The consistent group clock ensures the determinism of the replicas in the group with respect to clock-related operations, is monotonically increasing, has bounded increment, skew and drift. The consistent time service provides benefits for active replication during normal operation, as well as passive replication and semi-active replication to ensure a consistent monotonically increasing clock when the primary replica fails and a backup replica takes over as the new primary replica. The consistent time service provided is transparent to the application and guarantees group clock consistency despite replica failures or adding new or repaired replicas. |
| FILED | Friday, January 02, 2004 |
| APPL NO | 10/751264 |
| ART UNIT | 2155 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/202 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 07332550 | Matyjaszewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania); Nicolay Tsarevsky (Pittsburgh, Pennsylvania) |
| ABSTRACT | This present invention is directed towards the identification or design, preparation, and use of suitable transition metal complexes for use as catalysts. The transition metal complexes may comprise heterodonor ligands. The present invention is also directed toward a method of determining the suitability of a transition metal complex for use in a catalytic reaction, such as, but not limited to, atom transfer radical polymerization (“ATRP”), atom transfer radical addition (“ATRA”), atom transfer radical cyclization (“ATRC”), and other catalytic redox reactions. The method assists in the approximate determination of the fundamental properties of the transition metal complex in a reaction media, such as, but not limited to, solubility, redox potential, stability towards acidic, basic, or ionic species, conditional radically transferable atom phylicity, and propensity toward disproportionation and therefore, the suitability of the complex to be used as a catalyst in the reaction media. The method provides a basis for prediction and evaluation of the properties of a transition metal complex for a particular selective catalytic reaction in a broad range of reaction environments. An understanding of the principles of the disclosed method allows a transition metal complex to be tuned to specific reaction medium by selecting a transition metal complex and ligand combination having the desired qualities. |
| FILED | Friday, October 10, 2003 |
| APPL NO | 10/684137 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 526/91 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 07333614 | Jarosinski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | QUALCOMM Incorporated (San Diego, California) |
| INVENTOR(S) | Tad Jarosinski (San Diego, California); Daniel H. Agre (La Jolla, California); Stephen S. Carter (San Diego, California); Mehraban Iraninejad (Del Mar, California); Joseph P. Odenwalder (Rancho Santa Fe, California); Roy Franklin Quick (San Diego, California); Charles E. Wheatley (Del Mar, California) |
| ABSTRACT | A system and method for encrypting all channels of a wireless spread spectrum communication at the chip level. The PN sequence is encrypted with one or more encryption sequences and then used to spread the signal. |
| FILED | Friday, November 16, 2001 |
| APPL NO | 09/991506 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Cryptography 380/268 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07332908 | Nayak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Krishna S. Nayak (Los Angeles, California); Brian A. Hargreaves (San Francisco, California) |
| ABSTRACT | Disclosed is a wideband SSFP, wherein a standard balanced SSFP MRI sequence is played with repetition times of alternating lengths, TR and TRs, where TRs<TR. The result is significantly improved tradeoff between signal bandwidth and available acquisition interval lengths. This is particularly important as it enables the combination of balanced SSFP with high field imaging for many applications such as cardiac, musculoskeletal and abdominal imaging. |
| FILED | Thursday, May 04, 2006 |
| APPL NO | 11/381601 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07332825 | Annen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Aerodyne Research, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Kurt D. Annen (Rowely, Massachusetts); Jaime Woodroffe (North Reading, Massachusetts); Roger Putnam (Newton Highlands, Massachusetts) |
| ABSTRACT | This invention overcomes the disadvantages of the prior art by providing a power generating system particularly suitable for field use in remote locations, which is fuel-efficient, relatively quiet, tolerant of dust, capable of operating on low grade logistics and diesel-like fuels and capable of generating between 500 W and 2 KW of continuous electrical power. This generating system employs a two-cycle MICE generator having a piston that operates within a cylinder, and an interconnected, axially moving piston shaft that oscillates an alternator coil within a magnetic core. The piston shaft is attached to, and resisted by, the free end of a strong spring with a second, opposing end fixed to the MICE casing. To control operation of the MICE generator a dual clipper circuit is operatively connected with the alternator coil. The clipper circuit senses the current and at least two voltage levels and applies at least two respective loads in response to the sensed voltage levels and current so as to (a) prevent overstroke of the piston and (b) control power output of the alternator coil. The MICE generator also includes a fuel intake preheater that selectively heats fuel/air mixture entering the casing and a controller that senses load on the alternator coil varies a level of preheating to thereby control a level of power output. |
| FILED | Friday, January 06, 2006 |
| APPL NO | 11/327732 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Prime-mover dynamo plants 290/1.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07332174 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wyeth Holdings Corporation (Madison, New Jersey); The United States of America as represented by the Uniformed Services University of Health Sciences (Washington, District of Columbia) |
| INVENTOR(S) | Bruce A. Green (New City, New York); Randall K. Holmes (Golden, Colorado); Michael G. Jobling (Aurora, Colorado); Duzhang Zhu (Pomona, New York) |
| ABSTRACT | Mutant cholera holotoxins having single or double amino acid substitutions or insertions have reduced toxicity compared to the wild-type cholera holotoxin. The mutant cholera holotoxins are useful as adjuvants in antigenic compositions to enhance the immune response in a vertebrate host to a selected antigen from a pathogenic bacterium, virus, fungus, or parasite, a cancer cell, a tumor cell, an allergen, or a self-molecule. |
| FILED | Wednesday, June 05, 2002 |
| APPL NO | 10/478308 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/261.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07332527 | Bronich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Tatiana K. Bronich (Omaha, Nebraska); Alexander V. Kabanov (Omaha, Nebraska) |
| ABSTRACT | The present invention provides polymer micelles with cross-linked ionic cores as delivery vehicles for therapeutics, diagnostics, nucleic acids, proteins, small molecules and the like. The present invention provides additionally methods of synthesis and uses for such micelles. |
| FILED | Friday, May 16, 2003 |
| APPL NO | 10/440221 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/772.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07333051 | Moch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Thomas A. Moch (Owego, New York) |
| ABSTRACT | A method (for example, machine-implemented, e.g., via a receiver), for determining whether a transmitted pulsed-signal is a linear or non-linear frequency modulated (FM) signal, includes: iteratively determining upper and lower bound slopes associated with frequency components of a pulse of a signal during a time period of the pulse; and comparing each determined upper bound slope to a previous or initial upper bound reference slope and comparing each determined lower bound slope to a previous or initial lower bound reference slope in order to determine the linearity, or non-linearity, of the signal. |
| FILED | Friday, November 19, 2004 |
| APPL NO | 10/992085 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 19, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080219.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page