FedInvent™ Patents
Patent Details for Tuesday, April 08, 2008
This page was updated on Monday, March 27, 2023 at 12:56 AM GMT
Department of Defense (DOD)
| US 07353580 | Hall |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | Terence F. W. Hall (Santa Monica, California) |
| ABSTRACT | In accordance with the present invention, there is provided a method of automatically verifying the acceptable insertion of at least one Z-pin into a composite laminate. The method comprises the initial step of positioning at least one Z-pin upon the composite laminate. Thereafter, an insertion force is applied to the Z-pin at a first level which is sufficient to commence an insertion process wherein the Z-pin is driven into the composite laminate at a first insertion speed. The insertion force applied to the Z-pin is continuously monitored, with the first insertion speed being reduced to a second insertion speed in response to a monitored increase in the insertion force from a first level to a second level. The application of the insertion force to the Z-pin is discontinued and the insertion process terminated in response to a monitored increase in the insertion force from the second level to a third level. To confirm an acceptable insertion, the reduction from the first insertion speed to the second insertion speed is verified, as is the increase of the insertion force to the third level. |
| FILED | Tuesday, November 22, 2005 |
| APPL NO | 11/284605 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/407.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07353592 | Tebbe et al. |
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| ASSIGNEE(S) | Harris Corporation (Melbourne, Florida) |
| INVENTOR(S) | Dennis Tebbe (Melbourne, Florida); Thomas Smyth (Palm Bay, Florida); Terry Provo (Indialantic, Florida); Dara Ruggiero (Melbourne, Florida) |
| ABSTRACT | Method for fabricating a textured dielectric substrate (400) for an RF circuit. The method can include the step (104) of selecting a plurality of dielectric substrate materials, each having a distinct combination or set of electrical properties that is different from the combination of electrical properties of every other one of dielectric substrate materials. Selecting a textured substrate patter (106) which is comprised of at least two types of distinct areas respectively having the distinct sets of electrical properties, with each distinct area dimensioned much smaller than a wavelength at a frequency of interest. Cutting the dielectric substrate materials (202, 204) into a size and shape consistent with the distinct areas of the selected pattern so as to form a plurality of dielectric pieces (206, 208). Arranging the dielectric pieces on a base plate (302) in accordance with the selected pattern to form the textured dielectric substrate. |
| FILED | Thursday, January 11, 2007 |
| APPL NO | 11/622012 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/830 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07353695 | Fitch et al. |
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| ASSIGNEE(S) | BioScale, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric Fitch (Arlington, Massachusetts); Stuart Wenzel (San Francisco, California) |
| ABSTRACT | A method and system for determining properties of a fluid involves interacting the fluid with a standing wave in a first state to establish the standing wave in a second state, analyzing an electric signal associated with the standing wave to determine a characteristic associated with the second state, and determining the property of the fluid by comparing the characteristic with a function that associates a plurality of properties with a corresponding plurality of characteristics. The characteristic can include a maximum phase slope, a phase slope associated with a resonant frequency, a maximum magnitude associated with the resonant frequency, the value of the resonant frequency, or any combination thereof. |
| FILED | Monday, May 14, 2007 |
| APPL NO | 11/748155 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/54.250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07353740 | Hoffman |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brian R. Hoffman (Budd Lake, New Jersey) |
| ABSTRACT | A gun barrel adaptor includes a body having a central bore therethrough and including a flange, the flange having a hole therethrough, the body having a lower side on one side of the flange and an upper side on another side of the flange; a flat spring attached to a lower side of the flange; a stop disposed in the hole in the flange and extending above an upper side of the flange, the flat spring being operable to resist movement of the stop towards the lower side of the body; and at least one locking tab disposed on the upper side of the body. The gun barrel adaptor provides for quick change modularity of muzzle devices without the use of any special tools. |
| FILED | Tuesday, November 15, 2005 |
| APPL NO | 11/164219 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/14.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354021 | Leupold |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Herbert A. Leupold (Eatentown, New Jersey) |
| ABSTRACT | A toroidally shaped magnetic device with distortion-free exit and access ports provides toroidal magnetic ionic drive systems for vehicles that achieve a more operationally efficient, uniform and stronger radial magnetic field. This is accomplished by magnetizing a group of magic cylinder sections in a cylindrical direction and affixing them to a uniformly magnetized cylindrical shell with no magnetic field in its central cavity to produce composite cylindrical magnetic segments magnetized in a cylindrical direction with a central cavity and a uniform interior magnetic field. The composite segments are then bent into a toroidal tube and configured in such a way that longitudinal slots can be removed from the outer surface for exit and access ports. Other embodiments include a magnetic propulsion system for space vehicles and methods for magnetizing the toroidal ionic drive structure for a vehicle. |
| FILED | Friday, June 01, 2007 |
| APPL NO | 11/809631 |
| ART UNIT | 2832 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/171.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354033 | Murphey et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Thomas W Murphey (Albuquerque, New Mexico); Eric L Pollard (Albuquerque, New Mexico) |
| ABSTRACT | A tape-spring shaped, articulating member used in deployable structures having a resilient, compliant hinge region and rigid non-hinge regions, thereby enabling a smaller fold radius and greater packaging efficiency. The increased compliance in the hinge region may be obtained by using a more compliant material in the hinge region or reducing the cross-sectional area in the hinge region. The hinge region may be reinforced with integrated shape memory alloy features serving as folding mandrels, to enhance structural stiffness and strength performance of the hinge, and to exhibit authority over the rate and sequencing of strain release when deployed. |
| FILED | Tuesday, August 01, 2006 |
| APPL NO | 11/461547 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Spring devices 267/160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354044 | Peiten et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Peiten (La Puente, California); Joe G. Tom (Vicksburg, Mississippi); Charles A. Weiss, Jr. (Clinton, Mississippi); Philip G. Malone (Vicksburg, Mississippi); Steven L. Larson (Vicksburg, Mississippi) |
| ABSTRACT | A backstop for decelerating and trapping projectiles includes a support structure having at least one bin shielded from incoming rounds. A trapping medium, such as a resilient granular ballistic medium and a hydrated SAP gel, is disposed contiguously on an upper surface and within the bins. Bins are defined by transverse baffles spanning the width of the backstop. The baffles are preferably constructed of a non-ricochet material. Vibrations will urgetrapped rounds downwards into the bins. In embodiments, the lower surface of one or more bins declines toward either or both sides of the backstop, such that vibration urges spent rounds towards collection points along the sides of the backstop. Access ports may be provided in the backstop sidewalls proximate these collection points to allow for removal of spent rounds. The volume removed may be filtered to reclaim projectile trapping medium for reuse. |
| FILED | Wednesday, May 19, 2004 |
| APPL NO | 10/848433 |
| ART UNIT | 3711 — Amusement and Education Devices |
| CURRENT CPC | Amusement devices: Games 273/410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354216 | Dunmire et al. |
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| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Christopher F. Dunmire (Palos Verdes Estates, California); Trung N. Tran (Torrance, California); Christopher L. Scott (Los Alamitos, California) |
| ABSTRACT | A grease seal cup for a splined joint between a drive shaft and a driven shaft comprises a cylindrical portion adapted to form a seal with the outer surface of the drive shaft and a seal with a sealing member, such as a spanner nut, of the driven shaft. The grease seal cup, comprising a flexible polymer material, tightly squeezed during installation to form the seals. The pre-fabricated light weight grease seal cup can be used in existing splined joints without adversely affecting the weight balance. |
| FILED | Tuesday, April 12, 2005 |
| APPL NO | 11/103973 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Joints and connections 43/359.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354277 | Hougham et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Gareth G. Hougham (Ossining, New York); Brian S. Beaman (Cary, North Carolina); Evan G. Colgan (Chestnut Ridge, New York); Paul W. Coteus (Yorktown Heights, New York); Stefano S. Oggioni (Besana in Brianza, Italy); Enrique Vargas (Bronx, New York) |
| ABSTRACT | A land grid array (LGA) interposer structure, including an electrically insulating carrier plane, and at least one interposer mounted on a first surface of said carrier plane. The interposer possesses a hemi-toroidal configuration in transverse cross-section and is constituted of a dielectric elastomeric material. A plurality of electrically-conductive elements are arranged about the surface of the at least one hemi-toroidal interposer and extend radically inwardly and downwardly from an uppermost end thereof into electrical contact with at least one component located on an opposite side of the electrically insulating carrier plane. Provided is also a method of producing the land grid array interposer structure. |
| FILED | Monday, October 01, 2007 |
| APPL NO | 11/865293 |
| ART UNIT | 2839 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Electrical connectors 439/66 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354322 | Carver et al. |
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| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Reed Carver (Aurora, Ohio); Brian M. Kolkowski (Leroy, Ohio) |
| ABSTRACT | The present invention relates to a watercraft with an improved waterjet propulsion system. The present invention further relates to a waterjet propulsion system with an improved steering nozzle design. The watercraft preferably is either what is known as a jet ski, a boat or a ship. A watercraft can be propelled by the thrust produced by a high-speed waterjet discharged from a nozzle located at the rear of the watercraft. A device that enables this type of propulsion is called a waterjet propulsor or a propulsor. Larger watercraft, such as a boat or a ship may often have two or more waterjet propulsors. The improved steering nozzle design incorporates a groove(s) or a channel(s) that is formed or machined into the steering nozzle wall thickness and does not exceed the thickness of the wall. The groove(s) or channel(s) begins at a point between the steering nozzle inlet and exit and ends at a point near or at the exit of the steering nozzle. The groove(s) or channel(s) is preferably recessed into the interior surface of the steering nozzle. |
| FILED | Tuesday, September 23, 2003 |
| APPL NO | 10/668426 |
| ART UNIT | 3617 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Marine propulsion 440/38 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354329 | Derraa |
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| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Ammar Derraa (Boise, Idaho) |
| ABSTRACT | A substrate is provided and is configurable into a base plate for a field emission display. A plurality of discrete, segmented regions of field emitter tips are formed by at least removing portions of the substrate. The regions are electrically isolated into separately-addressable regions. In another embodiment, a plurality of field emitters are formed from material of the substrate and arranged into more than one demarcated, independently-addressable region of emitters. |
| FILED | Wednesday, August 17, 2005 |
| APPL NO | 11/207010 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp or space discharge component or device manufacturing 445/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354432 | Eells et al. |
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| ASSIGNEE(S) | MCW Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Janis T. Eells (Madison, Wisconsin); Margaret T. T. Wong-Riley (Brookfield, Wisconsin); Harry T. Whelan (Whitefish Bay, Wisconsin) |
| ABSTRACT | A method of treating visual system disease is disclosed. One embodiment comprises the steps of (a) exposing a component of a patient's visual system to light treatment, wherein the light treatment is characterized by wavelength of between 630-1000 nm and power intensity between 10-90 mW/cm2 for a time of 1-3 minutes, and (b) observing restoration of visual system function. |
| FILED | Friday, January 16, 2004 |
| APPL NO | 10/758793 |
| ART UNIT | 3739 — Optics |
| CURRENT CPC | Surgery 66/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354471 | Hampden-Smith et al. |
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| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark J. Hampden-Smith (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); Quint H. Powell (Albuquerque, New Mexico); Daniel J. Skamser (Albuquerque, New Mexico); James Caruso (Albuquerque, New Mexico); Clive D. Chandler (Portland, Oregon) |
| ABSTRACT | Provided are silver-containing powders and a method and apparatus for manufacturing the silver-containing particles of high quality, of a small size and narrow size distribution. An aerosol is generated from liquid feed and sent to a furnace, where liquid in droplets in the aerosol is vaporized to permit formation of the desired particles, which are then collected in a particle collector. The aerosol generation involves preparation of a high quality aerosol, with a narrow droplet size distribution, with close control over droplet size and with a high droplet loading suitable for commercial applications. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/949601 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/332 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354563 | Smalley et al. |
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| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard E. Smalley (Houston, Texas); Daniel T. Colbert (Houston, Texas); Hongjie Dai (Sunnyvale, California); Jie Liu (Chapel Hill, North Carolina); Andrew G. Rinzler (Newberry, Florida); Jason H. Hafner (Houston, Texas); Ken Smith (Katy, Texas); Ting Guo (Davis, California); Pavel Nikolaev (Houston, Texas); Andreas Thess (Kusterdingen, Germany) |
| ABSTRACT | This invention relates generally to a fullerene nanotube purification process and more particularly to a purification process that comprises heating the fullerene nanotube-containing felt under oxidizing conditions to remove the amorphous carbon deposits and other contaminating materials. In a preferred mode of this purification procedure, the felt is heated in an aqueous solution of an inorganic oxidant, such as nitric acid, a mixture of hydrogen peroxide and sulfuric acid, or a potassium permanganate. Preferably, fullerene nanotube-containing felts are refluxed in an aqueous solution of an oxidizing acid at a concentration high enough to etch away amorphous carbon deposits within a practical time frame, but not so high that the fullerene nanotube material will be etched to a significant degree. When material having a high proportion of fullerene nanotubes is purified, the preparation produced will be enriched in fullerene nanotubes, so that the fullerene nanotubes are substantially free of other material. |
| FILED | Tuesday, August 22, 2006 |
| APPL NO | 11/507960 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354626 | Patrissi et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Charles J. Patrissi (Newport, Rhode Island); Russell R. Bessette (Mattapoisett, Massachusetts); Louis G. Carreiro (Westport, Massachusetts); Yong K. Kim (Dartmouth, Massachusetts); Thomas M. Arruda (Quincy, Massachusetts); Craig M. Deschenes (Somerset, Massachusetts) |
| ABSTRACT | A direct charging electrostatic flocking method is provided for the fabrication of a fibrous structure. Fibers are deposited directly on a first electrically conductive surface while a second electrically conductive surface with an adhesive thereon is disposed over the first surface. A vacuum is created in the space between the first electrically conductive surface and the second electrically conductive surface. The vacuum is then filled with sulfur hexafluoride gas. An electric field is generated between the first and second electrically conductive surfaces. The fibers leave the first electrically conductive surface, accelerate through the electric field and sulfur hexafluoride gas, and are coupled on one end thereof to the adhesive. As a result of using sulfur hexafluoride rather than air there is an increase in fiber density of the fibrous structure. |
| FILED | Thursday, October 26, 2006 |
| APPL NO | 11/586277 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/462 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354706 | Rowlen et al. |
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| ASSIGNEE(S) | The Regents of The University of Colorado, a body corporate (Boulder, Colorado) |
| INVENTOR(S) | Kathy L. Rowlen (Longmont, Colorado); John W. Birks (Longmont, Colorado); Christopher Bowman (Boulder, Colorado); Hadley Sikes (Westminster, Colorado); Ryan Hansen (Boulder, Colorado); Robert Kuchta (Boulder, Colorado) |
| ABSTRACT | The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In an embodiment, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another embodiment, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another embodiment, sufficient polymer forms to be detectable by visual inspection. |
| FILED | Thursday, March 09, 2006 |
| APPL NO | 11/372485 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354713 | Mertz et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Janet E. Mertz (Madison, Wisconsin); Eric Anthony Ariazi (Chicago, Illinois) |
| ABSTRACT | The present invention provides that ERRγ is both a breast cancer biomarker and a breast cancer treatment target. A high ERRγ level in breast cancer cells indicates good prognosis. A high level of ERRγ in breast tissue suspected of being cancerous is indicative of breast cancer. Analyzing ERRγ status and optionally along with the status of ERα can help breast cancer patients make treatment choices. Furthermore, breast cancer can be treated by decreasing ERRγ activity in breast cancer cells. |
| FILED | Wednesday, September 03, 2003 |
| APPL NO | 10/654253 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354761 | Schultz et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason Chin (Cambridge, United Kingdom); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (Lancaster, Pennsylvania); Miro Pastrnak (San Diego, California); Steven William Santoro (Cambridge, Massachusetts); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Tuesday, October 18, 2005 |
| APPL NO | 11/254170 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354780 | Feng et al. |
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| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Milton Feng (Champaign, Illinois); Nick Holonyak, Jr. (Urbana, Illinois); Richard Chan (Champaign, Illinois) |
| ABSTRACT | A method for producing an optical output, including the following steps: providing first and second electrical signals; providing a bipolar light-emitting transistor device that includes collector, base, and emitter regions; providing a collector electrode coupled with the collector region and an emitter electrode coupled with the emitter region, and coupling electrical potentials with respect to the collector and emitter electrodes; providing an optical coupling in optical communication with the base region; providing first and second base electrodes coupled with the base region; and coupling the first and second electrical signals with the first and second base electrodes, respectively, to produce an optical output emitted from the base region and coupled into the optical coupling, the optical output being a function of the first and second electrical signals. |
| FILED | Wednesday, July 06, 2005 |
| APPL NO | 11/175995 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354809 | Yuan et al. |
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| ASSIGNEE(S) | Wisconsin Alumi Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hao-Chih Yuan (Madison, Wisconsin); Guogong Wang (Madison, Wisconsin); Mark A. Eriksson (Madison, Wisconsin); Paul G. Evans (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Zhenqiang Ma (Middleton, Wisconsin) |
| ABSTRACT | This invention provides methods for fabricating thin film electronic devices with both front- and backside processing capabilities. Using these methods, high temperature processing steps may be carried out during both frontside and backside processing. The methods are well-suited for fabricating back-gate and double-gate field effect transistors, double-sided bipolar transistors and 3D integrated circuits. |
| FILED | Monday, February 13, 2006 |
| APPL NO | 11/276065 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355015 | Dickson et al. |
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| ASSIGNEE(S) | Georgetown University School of Medicine (Washington, District of Columbia) |
| INVENTOR(S) | Robert B. Dickson (Silver Spring, Maryland); Chen-Yong Lin (Falls Church, Virginia); Michael Johnson (Rockville, Maryland); Shaomeng Wang (Rockville, Maryland); Istvan Enyedy (Mount Ranier, Maryland) |
| ABSTRACT | The invention is directed to a method of detecting a malignancy or a pre-malignant lesion in breast or other tissue, or a pathologic condition, by detecting the presence of single-chain or two-chain forms of matriptase in the tissue. The invention is further directed to a method of treating malignancies, which have the phenotype of matriptase production by administering a tumor formation inhibiting effective amount of concentrate of Bowman-Birk inhibitor (BBIC), or other matriptase inhibitor. The invention also is directed to nucleic acids encoding a matriptase protein or fragments thereof, and their use for structure elucidation and modeling to identify other inhibitors of matriptase, as well as to methods of identifying matriptase modulating agents, including activators and inhibitors. |
| FILED | Friday, March 10, 2000 |
| APPL NO | 09/936333 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355215 | Parikh et al. |
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| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Primit Parikh (Goleta, California); Yifeng Wu (Goleta, California); Adam William Saxler (Durham, North Carolina) |
| ABSTRACT | High electron mobility transistors (HEMT) are provided having an output power of greater than 3.0 Watts when operated at a frequency of at least 30 GHz. The HEMT has a power added efficiency (PAE) of at least about 20 percent and/or a gain of at least about 7.5 dB. The total width of the HEMT is less than about 6.0 mm. |
| FILED | Monday, December 06, 2004 |
| APPL NO | 11/005423 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355317 | Greywall |
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| ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Dennis S. Greywall (Whitehouse Station, New Jersey) |
| ABSTRACT | A MEMS device having a movable plate supported on a substrate by a support structure that is hidden under the plate and yet which can be implemented to enable rotation of the plate with respect to the substrate about a rotation axis lying at the plate surface. As a result, the support structure does not take up any area within the plane of the plate, while enabling rotation of the plate, during which the plate does not substantially move sideways. The latter property reduces potential physical interference between neighboring plates in an arrayed MEMS device and enables implementation of a segmented mirror having relatively narrow gaps between adjacent segments and, thus, a relatively large fill factor, e.g., at least 98%. |
| FILED | Thursday, March 31, 2005 |
| APPL NO | 11/095076 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355454 | Papaefthymiou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Marios C. Papaefthymiou (Ann Arbor, Michigan); Visvesh S. Sathe (Ann Arbor, Michigan); Conrad H. Ziesler (Los Gatos, California) |
| ABSTRACT | A boost circuit is disclosed that includes a plurality of transistors connected between complementary phases of a clock signal. The boost circuit further includes a first electrical node connected between at least two of the plurality of transistors wherein the plurality of transistors are configured to generate a second voltage from a first voltage at the electrical node in response to the clock signal. |
| FILED | Wednesday, June 15, 2005 |
| APPL NO | 11/153135 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Electronic digital logic circuitry 326/93 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355492 | Hyman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Xcom Wireless (Signal Hill, California) |
| INVENTOR(S) | Daniel J. Hyman (Signal Hill, California); Roger T. Kuroda (Poway, California) |
| ABSTRACT | The inventions presented herein provide a electronically controlled phase shifters that incorporate analog and digital phase shift architectures in a novel manner that realizes the best advantages of each architecture. This combination of complementary phase shift architectures provides the high-performance and low loss characteristics of switched digital phase shift architectures with the high resolution and precision of continuous analog phase shift architectures. The circuit embodiments are electronically controlled, which simplifies implementation of what is a complex circuit. The analog phase shift elements comprise electronically-tuned varactors, which provide fine resolution and enables the incorporation of active compensation for manufacturing variation before use or for environmental conditions during use. |
| FILED | Thursday, March 31, 2005 |
| APPL NO | 11/094481 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355513 | Brockel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth H. Brockel (Neptune, New Jersey); Harry G. Ivory (Bordentown, New Jersey); Fenton K. Yip (Edison, New Jersey); John P. Finn (West Conshohocken, Pennsylvania); James E. Hagerman (Glen Mills, Pennsylvania) |
| ABSTRACT | A survivor locator system allows for the detection of the location for a person who is lost and requires recovery and extraction from their current environment. By using a phase matched antenna set, a GPS receiver, and a handheld simplified beacon-equipped survival transponder, an estimated distance and bearing data set can be retrieved. If this data set estimation is then fed through an error reduction filter, such as a Kalman filtering algorithm, continually refined location coordinates can be generated, leading the search and rescue crew members to the survivor. The survivor locator system and methods provide a handheld survival radio with reduced complexity. |
| FILED | Friday, December 23, 2005 |
| APPL NO | 11/318141 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/539.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355553 | Ryken, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marvin L. Ryken, Jr. (Oxnard, California); Albert F. Davis (Ventura, California) |
| ABSTRACT | A microstrip antenna configured to wrap around approximately 270 degrees a projectile's body without interfering with the aerodynamic design of the projectile. The microstrip antenna has two identical grounded quarter wavelength microstrip antenna elements positioned around the circumference of the projectile's body. The antenna has an operating frequency of 425 MHz ±375 KHz, a maximum diameter of ten inches and a maximum length of nine inches. The microstrip antenna outputs a pair of equal amplitude flight termination signals and produces a quasi omni-directional radiation pattern with linear polarization. |
| FILED | Wednesday, December 06, 2006 |
| APPL NO | 11/645266 |
| ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/705 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355561 | Clarke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jerry A. Clarke (Abingdon, Maryland); John M. Vines (Conowingo, Maryland); Eric R. Mark (Bel Air, Maryland) |
| ABSTRACT | Systems and methods for providing images are disclosed. An exemplary embodiment of the system for providing images includes a first image display device for displaying a first image at a first image plane and a second image display device for displaying a second image at a second image plane. The first image plane is in front of the second image plane relative to an audience. The system also includes a real-object tracking system for tracking the position and orientation of a real object positioned between the first image plane and the second image plane and a video sub-system coupled to the first and second image display devices and the real-object tracking system for synchronizing the first image with the second image and the first and second images with the position and orientation of the real object placed between the first and second image planes. |
| FILED | Tuesday, September 14, 2004 |
| APPL NO | 10/939417 |
| ART UNIT | 2629 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355707 | Videen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gorden Videen (Silver Spring, Maryland) |
| ABSTRACT | A system and method and for analyzing dew in a system of interest are provided. A representative method comprises receiving infrared information corresponding to a degree of polarization of dew in a particular environment, and using the degree of polarization to determine dew presence in the environment. Changes in the degree of polarization can be attributed to changes in the density, size or shadowing of the dew drops. Infrared emissions information can be detected and accumulated over a range of emission angles and over a period of time. The system compares the accumulated data for the particular environment to detect the presence of dew, the rate of growth of the dew and the change in characteristics of dew over a period of time starting from a first time interval. The system also compares the accumulated data with other previous accumulated data from the environment to detect if changes should be made to the environment. |
| FILED | Friday, September 09, 2005 |
| APPL NO | 11/223250 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/364 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355716 | de Boer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Johannes F. de Boer (Somerville, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts); Brett E. Bouma (Quincy, Massachusetts) |
| ABSTRACT | Apparatus, method, logic arrangement and storage medium are provided for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (“LCI”) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source can be split into N spectral bands. The N spectral bands can be individually detected and processed to provide an increase in the signal-to-noise ratio by a factor of N. Each spectral band may be detected by a separate photo detector and amplified. For each spectral band, the signal can be band p3 filtered around the signal band by analog electronics and digitized, or, alternatively, the signal may be digitized and band pass filtered in software. As a consequence, the shot noise contribution to the signal is likely reduced by a factor equal to the number of spectral bands, while the signal amplitude can remain the same. The reduction of the shot noise increases the dynamic range and sensitivity of the system. |
| FILED | Friday, January 24, 2003 |
| APPL NO | 10/501276 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/479 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355768 | Billmers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard I. Billmers (Langhorne, Pennsylvania); Elizabeth J. Billmers (Langhorne, Pennsylvania); Mary E. Ludwig (Elkton, Maryland) |
| ABSTRACT | A narrowband, tunable filter with a wide acceptance angle utilizes two holographic filter elements connected in series. The filter blocks light outside of a narrow spectral band of interest, while enabling light to be seen over a wide range of angles incident on the filter. |
| FILED | Friday, August 05, 2005 |
| APPL NO | 11/197796 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355769 | Pittman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Todd B. Pittman (Catonsville, Maryland); James D. Franson (Ellicott City, Maryland) |
| ABSTRACT | An optical switch and optical storage loop are used as the basis of a single-photon source and a quantum memory for photonic qubits. To operate as a single-photon source, the techniques include a source of a pair of photons, such as a parametric down-conversion crystal, which is known to emit photons in pairs. The detection of one member of the pair activates the switch, which re-routes the other member into the storage loop. The stored photon is then known to be circulating in the loop, and can be switched out of the loop at a later time chosen by the user, providing a single photon for potential use in a variety of quantum information processing applications. To operate as a quantum memory for photonic qubits, a single-photon in an arbitrary initial polarization state is coherently stored in the loop, and coherently switched out of the loop when needed. |
| FILED | Monday, March 27, 2006 |
| APPL NO | 11/390028 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356444 | Blemel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth Gerald Blemel (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus providing a means for assessment of the integrity of insulated conduits, harnesses, cables, pipelines and other interconnection systems constructed with integral sensitized media, discrete sensors, and electronics providing a means for transforming sensed data into information and a means for communicating information for the purpose of understanding the location, degree and risk of damage and deterioration, and the probable causes thereof. |
| FILED | Monday, June 26, 2006 |
| APPL NO | 11/474967 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356596 | Ramanujan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Architecture Technology Corp. (Eden Prairie, Minnesota) |
| INVENTOR(S) | Ranga S. Ramanujan (Eden Prairie, Minnesota); Maher N. Kaddoura (Eden Prairie, Minnesota); Xiaoming Wu (Eden Prairie, Minnesota); Kevin S. Millikin (St. Paul, Minnesota) |
| ABSTRACT | Automated techniques are described that provide continuous, uninterrupted operation of the secure packet tunnels in spite of access link flooding attacks. A system is described that includes a source device and a destination device coupled to a network. The source and destination devices may comprise, for example, edge routers that couple local area networks to the network via access links. The source device and the destination device establish a packet tunnel that has a source network address and a destination network address. Upon detecting a network attack, the destination device selects a new network address for at least one of the source network address and the destination network address and establishes a new packet tunnel with the source device. The source network address and the destination network address may comprise port numbers, Internet Protocol (IP) addresses, or other information describing the source and destination devices. |
| FILED | Friday, January 25, 2002 |
| APPL NO | 10/057043 |
| ART UNIT | 2141 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/227 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356784 | Dengi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cadence Design Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Enis Aykut Dengi (Tempe, Arizona); Stephen McCracken (Tempe, Arizona); Michael R. Kelly (Gibsonia, Pennsylvania); Matthew B. Phelps (Pittsburgh, Pennsylvania); Ibraz Mohammed (Tempe, Arizona) |
| ABSTRACT | A method determining an IC (integrated circuit) design includes: determining one or more design variables, wherein the one or more design variables include one or more device variables and one or more weights; determining one or more net lengths and one or more layout metrics from the one or more device variables and the one or more weights; and determining the IC design from the one or more device variables and the one or more net lengths. The IC design includes a schematic and a layout. The process can be repeated as needed according to performance criteria that may include circuit performance metrics and layout performance metrics. |
| FILED | Monday, December 06, 2004 |
| APPL NO | 11/006323 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 07353830 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington Research Foundation (Seattle, Washington) |
| INVENTOR(S) | Minako Yoshioka Lee (Seattle, Washington); David Rodney Eyre (Seattle, Washington); Mary Ann Eklof Weis (Everett, Washington) |
| ABSTRACT | A composition or device suitable for orthopedic or dental implantation to bone, characterized by tartrate-resistant acid phosphatase (TRAP) adsorbed to a porous hydroxyapatite substratum. |
| FILED | Thursday, June 17, 2004 |
| APPL NO | 10/870627 |
| ART UNIT | 3738 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery 128/898 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354432 | Eells et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | MCW Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Janis T. Eells (Madison, Wisconsin); Margaret T. T. Wong-Riley (Brookfield, Wisconsin); Harry T. Whelan (Whitefish Bay, Wisconsin) |
| ABSTRACT | A method of treating visual system disease is disclosed. One embodiment comprises the steps of (a) exposing a component of a patient's visual system to light treatment, wherein the light treatment is characterized by wavelength of between 630-1000 nm and power intensity between 10-90 mW/cm2 for a time of 1-3 minutes, and (b) observing restoration of visual system function. |
| FILED | Friday, January 16, 2004 |
| APPL NO | 10/758793 |
| ART UNIT | 3739 — Optics |
| CURRENT CPC | Surgery 66/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354568 | Meade et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Thomas Meade (Wilmette, Illinois); Scott Fraser (La Canada, California); Russell Jacobs (Pasadena, California) |
| ABSTRACT | The invention relates to novel magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances. |
| FILED | Monday, September 27, 1999 |
| APPL NO | 09/405046 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.363 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354586 | Brooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Peter C. Brooks (Carmel, New York); David A. Cheresh (Encinitas, California) |
| ABSTRACT | The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing αvβ3 antagonists. |
| FILED | Thursday, July 15, 2004 |
| APPL NO | 10/892789 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/152.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354589 | Gerhard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Wistar Institute (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Walter Gerhard (Philadelphia, Pennsylvania); Laszlo Otvos, Jr. (Audubon, Pennsylvania) |
| ABSTRACT | The present invention provides multiple antigenic agents compositions and the use thereof to prevent or treat viral infections. The multiple antigenic agents of the invention contain at least one of a B cell determinant, a T cell determinant, or a targeting molecule attached to a core peptide composed of Lys-Gly repeats. |
| FILED | Tuesday, March 29, 2005 |
| APPL NO | 11/093107 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/193.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354597 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Audrey M. Johnson (Cambridge, Massachusetts); Michael J. Cima (Winchester, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Methods and systems are provided for microscale lyophilization or microscale drying of agents of interest, such as pharmaceutical agents or other molecules that are unstable or easily degraded in solution. The drying method includes (a) providing a liquid comprising an agent of interest dissolved or dispersed in a volatile liquid medium; (b) depositing a microquantity (between 1 nL and 10 μL) of the liquid onto a preselected site of a substrate; and then (c) drying the microquantity by volatilizing the volatile liquid medium to produce a dry, solid form of the agent of interest. The lyophilization method includes freezing the microquantity of liquid after step (b) and before step (c). By processing the agent of interest in microquantities in controlled contact with a substrate surface, improved heat and mass transfer is provided, yielding better process control over drying of the agent of interest compared to conventional bulk drying or lyophilization. |
| FILED | Tuesday, December 03, 2002 |
| APPL NO | 10/308579 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/426 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354703 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Prasad Jallepalli (Baltimore, Maryland); Christoph Lengauer (Columbia, Maryland) |
| ABSTRACT | Securin-deficient cells and their isogenic securin-proficient counterparts are useful for screening potential anti-tumor agents. Potential therapeutic agents are screened for the ability to preferentially inhibit or kill a securin-deficient cell. The association of securin deficiency and chromosomal instability leading to aneuploidy, renders securin an excellent target for chemotherapeutic drug development. |
| FILED | Friday, March 23, 2001 |
| APPL NO | 09/815340 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354706 | Rowlen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of The University of Colorado, a body corporate (Boulder, Colorado) |
| INVENTOR(S) | Kathy L. Rowlen (Longmont, Colorado); John W. Birks (Longmont, Colorado); Christopher Bowman (Boulder, Colorado); Hadley Sikes (Westminster, Colorado); Ryan Hansen (Boulder, Colorado); Robert Kuchta (Boulder, Colorado) |
| ABSTRACT | The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In an embodiment, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another embodiment, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another embodiment, sufficient polymer forms to be detectable by visual inspection. |
| FILED | Thursday, March 09, 2006 |
| APPL NO | 11/372485 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354710 | Hogan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Genomics USA, Inc. (Pearland, Texas) |
| INVENTOR(S) | Michael Hogan (Tucson, Arizona); Sergy Lemeshko (Houston, Texas); Yuri Belosludtsev (The Woodlands, Texas); Tom Powdrill (College Station, Texas); Rahul Mitra (Pearland, Texas) |
| ABSTRACT | The present invention relates to simple method to fabricate DNA hybridization devices based upon adsorptive attachment of oligonucleotides to a positively charged surface. Such adsorbed oligonucleotide probes form a densely packed monolayer, which retains capacity for base-pair specific hybridization with a solution state nucleic acid target strand to form the duplex. However, both strand dissociation kinetics and the rate of DNase digestion suggest on symmetry grounds that solution-state nucleic acid binds to such adsorbed oligonucleotides to form a highly asymmetric and unwound duplex, with structural details that are substantially different from that known for the Watson-Crick DNA duplex. This novel nucleic acid duplex form can serve as the basis for a new class of hybridization device and methods for their use. It is also disclosed that new methods of nucleic acid duplex detection can be developed which are based upon the interaction of enzymes and dye labels with the unique structural characteristics of the non-helical duplex described herein. Preferred implementations of the invention include DNA microarrays, bead-based nucleic acid analysis, microelectronic devices to detect nucleic acid hybridization and more traditional methods of laboratory analysis, including hybridization on membranous and other solid supports. |
| FILED | Thursday, July 11, 2002 |
| APPL NO | 10/193938 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354713 | Mertz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Janet E. Mertz (Madison, Wisconsin); Eric Anthony Ariazi (Chicago, Illinois) |
| ABSTRACT | The present invention provides that ERRγ is both a breast cancer biomarker and a breast cancer treatment target. A high ERRγ level in breast cancer cells indicates good prognosis. A high level of ERRγ in breast tissue suspected of being cancerous is indicative of breast cancer. Analyzing ERRγ status and optionally along with the status of ERα can help breast cancer patients make treatment choices. Furthermore, breast cancer can be treated by decreasing ERRγ activity in breast cancer cells. |
| FILED | Wednesday, September 03, 2003 |
| APPL NO | 10/654253 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354722 | Thomsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Signal Pharmaceuticals (San Diego, California) |
| INVENTOR(S) | Gerald H. Thomsen (Port Jefferson, New York); Jeffrey Wrana (Toronto, Canada) |
| ABSTRACT | This invention provides unique members of the Hect family of ubiquitin ligases that specifically target BMP and TGFβ/activin pathway-specific Smads. The novel ligases have been named Smurf1 and Smurf2. They directly interact with Smads1 and 5 and Smad7, respectively, and regulate the ubiquitination, turnover and activity of Smads and other proteins of these pathways. Smurf1 interferes with biological responses to BMP, but not activin signaling. In amphibian embryos Smurf1 inhibits endogenous BMP signals, resulting in altered pattern formation and cell fate specification in the mesoderm and ectoderm. The present invention provides a unique regulatory link between the ubiquitination pathway and the control of cell fate determination by the TGFβ superfamily during embryonic development. Thus, Smurf1 is a negative regulator of Smad1 signal transduction, by targeting Smad1, Smurf1 blocks BMP signaling. In mammalian cells, Smurf2 suppresses TGFβ signalling, and in Xenopus, blocks formation of dorsal mesoderm and causes anterior truncation of the embryos. Smurf2 forms a stable complex with Smad7, which induces degradation and downregulation of TGFβ/activin signalling. |
| FILED | Monday, June 12, 2000 |
| APPL NO | 10/009945 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354729 | Rich |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HemoGenix, Inc. (Colorado Springs, Colorado) |
| INVENTOR(S) | Ivan N. Rich (Columbia, South Carolina) |
| ABSTRACT | The present invention relates generally to high-throughput assay methods that determine the proliferative status of hematopoietic stem and progenitor cells. The present invention further relates to high-throughput assays for screening compounds that modulate the growth of hematopoietic stem and progenitor cells and for identifying subpopulations thereof that are suitable for transplantation. The assay of the present invention is particularly useful for quality control and monitoring of the growth potential in the stem cell transplant setting and would provide improved control over the reconstitution phase of transplanted cells. |
| FILED | Tuesday, January 29, 2002 |
| APPL NO | 10/059521 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354730 | Rich |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HemoGenix, Inc. (Colorado Springs, Colorado) |
| INVENTOR(S) | Ivan N. Rich (Colorado Springs, Colorado) |
| ABSTRACT | The present invention relates generally to kits that provide reagent mixes and instructions for the use thereof, in performing high-throughput assay methods that determine the proliferative status of isolated target cell populations. The methods measure the luminescent output derived from the intracellular ATP content of incubated target cells, and correlate the luminescence with the proliferative status of the cells. The present invention further relates to kits that provide reagent mixes and instructions for high-throughput assays methods for screening compounds that may modulate the proliferative status of a target cell population. The kits of the present invention and methods therein described may be used for determining the proliferative status of any isolated cell line or type. The kits and methods of the present invention address the need for rapid assays that determine the proliferative status of isolated hematopoietic stem and progenitor cells and of subpopulations of differentiated cells thereof. |
| FILED | Thursday, August 21, 2003 |
| APPL NO | 10/645077 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354738 | Spiegelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jiandie Lin (Brookline, Massachusetts) |
| ABSTRACT | The invention provides isolated nucleic acid molecules, designated PGC-1β nucleic acid molecules, which encode novel PGC-1 related coactivator molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1β nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1β gene has been introduced or disrupted. The invention still further provides isolated PGC-1β proteins, fusion proteins, antigenic peptides and anti-PGC-1β antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |
| FILED | Thursday, April 27, 2006 |
| APPL NO | 11/413066 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354745 | Frey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Perry A. Frey (Madison, Wisconsin); Frank J. Ruzicka (Madison, Wisconsin) |
| ABSTRACT | Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds. Although enantiomerically pure β-amino acids, such as L-β-lysine, can be produced by standard chemical synthesis, this traditional approach is time consuming, requires expensive starting materials, and results in a racemic mixture which must be purified further. However, DNA molecules encoding lysine 2,3-aminomutase can be used to prepare L-β-lysine by methods that avoid the pitfalls of chemical synthesis. In particular, L-β-lysine can be synthesized by cultures of host cells that express recombinant lysine 2,3-aminomutase. Alternatively, such recombinant host cells can provide a source for isolating quantities of lysine 2,3-aminomutase, which in turn, can be used to produce L-β-lysine in vitro. |
| FILED | Tuesday, May 01, 2001 |
| APPL NO | 09/847010 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354756 | Benkovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J. Benkovic (State College, Pennsylvania); Charles P. Scott (Narberth, Pennsylvania); Ernesto V. Abel-Santos (State College, Pennsylvania) |
| ABSTRACT | Methods of producing cyclic peptides and splicing intermediates of peptides in a looped conformation are disclosed. The methods utilize the trans-splicing ability of split inteins to catalyze cyclization of peptides from a precursor peptide having a target peptide interposed between two portions of a split intein. The interaction of the two portions of the split intein creates a catalytically-active intein and also forces the target peptide into a loop configuration that stabilizes the ester isomer of the amino acid at the junction between one of the intein portions and the target peptide. A heteroatom from the other intein portion then reacts with the ester to form a cyclic ester intermediate. The active intein catalyzes the formation of an aminosuccinimide that liberates a cyclized form of the target peptide, which spontaneously rearranges to form the thermodynamically favored backbone cyclic peptide product. Also disclosed are nucleic acid molecules, polypeptides, methods for making cyclic peptides, methods of making libraries, and methods of screening peptides. |
| FILED | Saturday, December 18, 1999 |
| APPL NO | 09/868469 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354761 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason Chin (Cambridge, United Kingdom); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (Lancaster, Pennsylvania); Miro Pastrnak (San Diego, California); Steven William Santoro (Cambridge, Massachusetts); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Tuesday, October 18, 2005 |
| APPL NO | 11/254170 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354894 | Nadel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jay A. Nadel (San Francisco, California); Kiyoshi Takeyama (Tokyo, Japan) |
| ABSTRACT | Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic molecule, an antibody, or portion of an antibody that binds to and blocks the EGF receptor. The EGF-R antagonist is preferably administered by injection in an amount sufficient to inhibit formation of goblet cells in pulmonary airways. The degranulation of goblet cells that results in airway mucus production is thereby inhibited. Assays for screening candidate agents that inhibit goblet cell proliferation are also provided. |
| FILED | Wednesday, March 31, 2004 |
| APPL NO | 10/816159 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354897 | Gilbert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Gary E. Gilbert (Winchester, Massachusetts); Jialin Shi (Newton, Massachusetts) |
| ABSTRACT | A method and composition for inhibiting or slowing blood coagulation includes lactadherin, a fragment of lactadherin, a functional equivalent of lactadherin, or a functional equivalent of a fragment of lactadherin. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/516450 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354900 | Pereira et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Heloise Anne Pereira (Edmond, Oklahoma); James Chodosh (Edmond, Oklahoma); Michelle C. Callegan (Edmond, Oklahoma) |
| ABSTRACT | A method for treating ocular conditions such as bacterial keratitis, bacterial conjunctivitis, corneal ulcers and wounds, endophthalmitis, and blebitis in mammals, by using a native, synthetic, or recombinant CAP37, or effective peptide portions thereof including CAP37 peptides 20-44, 23-42, 102-122, and 120-146 and monocysteine derivatives of peptides 20-44 and 23-42. The CAP37, peptides, and peptide derivatives can also be used to store, clean, sterilize, or coat contact lenses, and may be used in media for storing mammalian corneal transplants. |
| FILED | Friday, April 25, 2003 |
| APPL NO | 10/423311 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354909 | Klinman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Dennis M. Klinman (Potomac, Maryland); Mayda Gursel (Ankara, Turkey); Daniela Verthelyi (Potomac, Maryland) |
| ABSTRACT | Novel methods for rapidly generating dendritic cells are disclosed herein. The methods include contacting a dendritic cell precursor with a D ODN to generate a mature dendritic cell. In one specific, non/limiting example, the method includes contacting the dendritic cell precursor or the mature dendritic cell with an antigen. The methods are of use both in vitro and in vivo. |
| FILED | Tuesday, August 13, 2002 |
| APPL NO | 10/486755 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355005 | Bram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Richard J. Bram (Rochester, Minnesota); Gotz Von Bulow (Carmel, Indiana) |
| ABSTRACT | A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, is shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e.g., during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions). |
| FILED | Friday, December 23, 2005 |
| APPL NO | 11/318156 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355010 | Lowery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | BellBrook Labs, LLC (Madison, Wisconsin) |
| INVENTOR(S) | Robert Lowery (Belleville, Wisconsin); Karen Kleman-Leyer (Madison, Wisconsin); Matt Staeben (Belleville, Wisconsin); Thane Westermeyer (Sun Prairie, Wisconsin) |
| ABSTRACT | The present invention relates to methods for detecting, quantifying and high throughput screening of donor-products and the catalytic activities generating the donor-products in group-transfer reactions. The invention further provides immunoassays, antibodies and kits that may be used to practice the methods of the invention. |
| FILED | Thursday, May 26, 2005 |
| APPL NO | 11/137947 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355012 | Pastan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Ira H. Pastan (Potomac, Maryland); Giuliana Salvatore (Naples, Italy); Richard Beers (Rockville, Maryland); Robert J. Kreitman (Potomac, Maryland) |
| ABSTRACT | Recombinant immunotoxins are fusion proteins composed of the Fv domains of antibodies fused to bacterial or plant toxins. RFB4 (Fv)-PE38 is an immunotoxin that targets CD22 expressed on B cells and B cell malignancies. The present invention provides antibodies and antibody fragments that have improved ability to bind the CD22 antigen of B cells and B cell malignancies compared to RFB4. Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells. Compositions that incorporate these antibodies into chimeric immunotoxin molecules that can be used in medicaments and methods for inhibiting the growth and proliferation of leukemia and lymphoma cells. |
| FILED | Wednesday, September 25, 2002 |
| APPL NO | 10/490535 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355015 | Dickson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgetown University School of Medicine (Washington, District of Columbia) |
| INVENTOR(S) | Robert B. Dickson (Silver Spring, Maryland); Chen-Yong Lin (Falls Church, Virginia); Michael Johnson (Rockville, Maryland); Shaomeng Wang (Rockville, Maryland); Istvan Enyedy (Mount Ranier, Maryland) |
| ABSTRACT | The invention is directed to a method of detecting a malignancy or a pre-malignant lesion in breast or other tissue, or a pathologic condition, by detecting the presence of single-chain or two-chain forms of matriptase in the tissue. The invention is further directed to a method of treating malignancies, which have the phenotype of matriptase production by administering a tumor formation inhibiting effective amount of concentrate of Bowman-Birk inhibitor (BBIC), or other matriptase inhibitor. The invention also is directed to nucleic acids encoding a matriptase protein or fragments thereof, and their use for structure elucidation and modeling to identify other inhibitors of matriptase, as well as to methods of identifying matriptase modulating agents, including activators and inhibitors. |
| FILED | Friday, March 10, 2000 |
| APPL NO | 09/936333 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355019 | Backer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SibTech, Inc. (Newington, Connecticut) |
| INVENTOR(S) | Marina V. Backer (W. Simsbury, Connecticut); Joseph M. Backer (W. Simsbury, Connecticut) |
| ABSTRACT | The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety bound to the targeting moiety; the biological conjugate having a covalent bond between the thiol group of SEQ ID NO:2 and a functional group in the binding moiety. The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety that comprises an adapter protein, the adapter protein having a thiol group; the biological conjugate having a disulfide bond between the thiol group of SEQ ID NO:2 and the thiol group of the adapter protein. The present invention is also directed to biological sequences employed in the above biological conjugates, as well as pharmaceutical preparations and methods using the above biological conjugates. |
| FILED | Friday, March 18, 2005 |
| APPL NO | 11/083508 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/399 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355037 | Beaucage et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Serge L. Beaucage (Silver Spring, Maryland); Andrzej Grajkowski (Bethesda, Maryland); Andrzej Wilk (N. Potomac, Maryland) |
| ABSTRACT | Provided is a hydroxyl-protected alcohol of the formula R—O—Pg, wherein Pg is a protecting group of the formula: wherein Y, Z, W, R1, R1a, R2, R2a, R3, R3a, R4, R4a, a, b, c, d, e and f are defined herein and R is a nucleosidyl group, an oligonucleotidyl group with 2 to about 300 nucleosides, or an oligomer with 2 to about 300 nucleosides. Also provided is a deprotection method, which includes heating the hydroxyl-protected alcohol at a temperature effective to cleave thermally the hydroxyl-protecting group therefrom. |
| FILED | Tuesday, December 03, 2002 |
| APPL NO | 10/497416 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/25.310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355079 | Scanlan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Thomas S. Scanlan (San Francisco, California); Matthew E. Hart (San Francisco, California); David K. Grandy (Portland, Oregon); James R. Bunzow (Portland, Oregon); Motonori Miyakawa (South San Francisco, California); Edwin Saavedra Tan (San Francisco, California); Katherine L. Suchland (Portland, Oregon) |
| ABSTRACT | Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. |
| FILED | Tuesday, April 05, 2005 |
| APPL NO | 11/099959 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/374 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355169 | McLuckey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Scott A. McLuckey (West Lafayette, Indiana); Gavin E. Reid (Lafayette, Indiana); James Mitchell Wells (Lafayette, Indiana) |
| ABSTRACT | A method of inhibiting the reaction between ions of opposite polarity is disclosed. The method includes exposing a population of ions to a resonance excitation frequency during a mass-to-charge altering reaction between a first subpopulation of ions and a second subpopulation of ions, the resonance excitation frequency being tuned to inhibit the mass-to-charge altering reaction between an ion of the first subpopulation of ions having a predetermined mass-to-charge ratio and an ion of the second subpopulation of ions so that when an ion of the first subpopulation of ions attains the predetermined mass-to-charge ratio, the ion having the predetermined mass-to-charge ratio is selectively inhibited from reacting with ions of the second subpopulation of ions. |
| FILED | Friday, May 05, 2006 |
| APPL NO | 11/418907 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355597 | Laidlaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brown University Research Foundation (Providence, Rhode Island) |
| INVENTOR(S) | David H Laidlaw (Barrington, Rhode Island); Andreas Wenger (Los Angeles, California) |
| ABSTRACT | Described is a system, method and computer program product for rendering volumetric multivalued primary data. The system includes a rendering engine having an input coupled to a source of multivalued primary data and an output coupled to a display. The rendering engine includes a data processor for calculating additional data values from the primary data, deriving at least one visual representation from the primary data and the additional data values, and mapping the derived visual representation through transfer functions to hardware primitives for volumetrically rendering the derived visual representation to provide a visualization. The system further includes a user interface for interacting with the visualization. The source of primary data can be a magnetic resonance imaging system, and the primary data may be a multivalued combination obtained from T1 weighted data, T2 weighted data, diffusion data, velocity data, magnetization transfer data, perfusion data, data derived from other imaging modalities (e.g., PET), and simulation data. The primary data can be diffusion tensor data generated by the MRI system from tissue, and the data processor operates to identify directed diffusion paths and to render the directed diffusion paths as thread-like structures. Indications of at least flowing blood velocity and vorticity can also be rendered from MRI data or from simulations. |
| FILED | Tuesday, May 06, 2003 |
| APPL NO | 10/431130 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355697 | Mertz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Edward L. Mertz (Washington, District of Columbia); James V. Sullivan (Bowie, Maryland) |
| ABSTRACT | Optical cells are non-actively compensated to ensure that a sample gap of a sample space remains nearly constant upon a change in temperature. Fluids can be flowed through the sample space of the optical cells. |
| FILED | Thursday, August 26, 2004 |
| APPL NO | 10/926405 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/246 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356113 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Tao Wu (Woburn, Massachusetts); Alex Stewart (Waltham, Massachusetts); Martin Stanton (Stow, Massachusetts); Walter Phillips (Arlington, Massachusetts); Daniel B. Kopans (Waban, Massachusetts); Richard Moore (Concord, Massachusetts) |
| ABSTRACT | A system for three-dimensional tomosynthesis imaging of a target element includes an image acquisition element and a processor. The image acquisition element obtains a plurality of images of the target element from a plurality of angles and includes a radiation source that is positionable at a plurality of angles with respect to the target element and a radiation detector. The radiation detector is positioned so as to detect radiation emitted by the radiation source passing through the target element and determine a plurality of attenuation values for radiation passing through the target element to establish a radiation absorbance projection image of the target element for a particular radiation source angle. The processor is configured to apply an iterative reconstruction algorithm to the radiation absorbance projection images of the target element obtained from a plurality of radiation source angles to generate a three-dimensional reconstruction of the target element. |
| FILED | Wednesday, February 11, 2004 |
| APPL NO | 10/776690 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356367 | Liang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Stony Brook, New York) |
| INVENTOR(S) | Zhengrong Liang (Stony Brook, New York); Dongqing Chen (Port Jefferson Station, New York); Bin Li (Centereach, New York); Clemente T. Roque (Stony Brook, New York); Eric E. Smouha (Northport, New York); Arie E. Kaufman (Plainview, New York); Mark R. Wax (Greenlawn, New York); Kevin Kreeger (E. Setauket, New York) |
| ABSTRACT | A computer based system and method of visualizing a region using multiple image data sets is provided. The method includes acquiring first volumetric image data of a region and acquiring at least second volumetric image data of the region. The first image data is generally selected such that the structural features of the region are readily visualized. At least one control point is determined in the region using an identifiable structural characteristic discernable in the first volumetric image data. The at least one control point is also located in the at least second image data of the region such that the first image data and the at least second image data can be registered to one another using the at least one control point. Once the image data sets are registered, the registered first image data and at least second image data can be fused into a common display data set. The multiple image data sets have different and complimentary information to differentiate the structures and the functions in the region such that image segmentation algorithms and user interactive editing tools can be applied to obtain 3d spatial relations of the components in the region. Methods to correct spatial inhomogeneity in MR image data is also provided. |
| FILED | Wednesday, June 06, 2001 |
| APPL NO | 10/297349 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07354287 | Hickam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Chris D. Hickam (Glasford, Illinois) |
| ABSTRACT | An electrical connector includes a housing that may form a first contact channel and a second contact channel. A first contact having a longitudinal axis may be disposed within the first contact channel, and a second contact may be disposed within the second contact channel. A shorting arm may be configured to move generally parallel to the longitudinal axis of the first contact between a first position and a second position. When the shorting arm is in the first position, the shorting arm electrically connects the first contact with the second contact, and when the shorting arm is in the second position, the shorting arm is separated from the first and second contacts. |
| FILED | Tuesday, October 31, 2006 |
| APPL NO | 11/590544 |
| ART UNIT | 2839 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Electrical connectors 439/188 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354465 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nuvera Fuel Cells, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Jian Lian Zhao (Belmont, Massachusetts); William F. Northrop (Ann Arbor, Michigan) |
| ABSTRACT | Devices for cooling and humidifying a reformate stream from a reforming reactor as well as related methods, modules and systems includes a heat exchanger and a sprayer. The heat exchanger has an inlet, an outlet, and a conduit between the inlet and the outlet. The heat exchanger is adapted to allow a flow of a first fluid (e.g. water) inside the conduit and to establish a heat exchange relationship between the first fluid and a second fluid (e.g. reformate from a reforming reactor) flowing outside the conduit. The sprayer is coupled to the outlet of the heat exchanger for spraying the first fluid exiting the heat exchanger into the second fluid. |
| FILED | Monday, June 20, 2005 |
| APPL NO | 11/156919 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Gas: Heating and illuminating 048/197.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354561 | Kong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Peter C. Kong (Idaho Falls, Idaho) |
| ABSTRACT | A chemical reactor and method for converting a first material into a second material is disclosed and wherein the chemical reactor is provided with a feed stream of a first material which is to be converted into a second material; and wherein the first material is combusted in the chemical reactor to produce a combustion flame, and a resulting gas; and an electrical arc is provided which is passed through or superimposed upon the combustion flame and the resulting gas to facilitate the production of the second material. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/992498 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354743 | Vlasenko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Elena Vlasenko (Davis, California); Joel Cherry (Davis, California); Feng Xu (Davis, California) |
| ABSTRACT | The present invention relates to methods for degrading a lignocellulosic material, comprising: treating the lignocellulosic material with an effective amount of one or more cellulolytic enzymes in the presence of at least one surfactant selected from the group consisting of a secondary alcohol ethoxylate, fatty alcohol ethoxylate, nonylphenol ethoxylate, tridecyl ethoxylate, and polyoxyethylene ether, wherein the presence of the surfactant increases the degradation of lignocellulosic material compared to the absence of the surfactant. The present invention also relates to methods for producing an organic substance, comprising: (a) saccharifying a lignocellulosic material with an effective amount of one or more cellulolytic enzymes in the presence of at least one surfactant selected from the group consisting of a secondary alcohol ethoxylate, fatty alcohol ethoxylate, nonylphenol ethoxylate, tridecyl ethoxylate, and polyoxyethylene ether, wherein the presence of the surfactant increases the degradation of lignocellulosic material compared to the absence of the surfactant; (b) fermenting the saccharified lignocellulosic material of step (a) with one or more fermentating microoganisms; and (c) recovering the organic substance from the fermentation. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/036871 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354755 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Midwest Research Institute (Kansas City, Missouri) |
| INVENTOR(S) | Min Zhang (Lakewood, Colorado); Yat-Chen Chou (Taipei, Taiwan) |
| ABSTRACT | The present invention briefly includes a transposon for stable insertion of foreign genes into a bacterial genome, comprising at least one operon having structural genes encoding enzymes selected from the group consisting of xylAxylB, araBAD and tal/tkt, and at least one promoter for expression of the structural genes in the bacterium, a pair of inverted insertion sequences, the operons contained inside the insertion sequences, and a transposase gene located outside of the insertion sequences. A plasmid shuttle vector for transformation of foreign genes into a bacterial genome, comprising at least one operon having structural genes encoding enzymes selected from the group consisting of xylAxylB, araBAD and tal/tkt, at least one promoter for expression of the structural genes in the bacterium, and at least two DNA fragments having homology with a gene in the bacterial genome to be transformed, is also provided. The transposon and shuttle vectors are useful in constructing significantly different Zymomonas mobilis strains, according to the present invention, which are useful in the conversion of the cellulose derived pentose sugars into fuels and chemicals, using traditional fermentation technology, because they are stable for expression in a non-selection medium. |
| FILED | Monday, May 01, 2000 |
| APPL NO | 09/565233 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354761 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason Chin (Cambridge, United Kingdom); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (Lancaster, Pennsylvania); Miro Pastrnak (San Diego, California); Steven William Santoro (Cambridge, Massachusetts); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Tuesday, October 18, 2005 |
| APPL NO | 11/254170 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354792 | Carey, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | James Edward Carey, III (Newton, Massachusetts); Eric Mazur (Concord, Massachusetts) |
| ABSTRACT | The present invention provides methods of fabricating a radiation-absorbing semiconductor wafer by irradiating at least one surface location of a silicon substrate, e.g., an n-doped crystalline silicon, by a plurality of temporally short laser pulses, e.g., femtosecond pulses, while exposing that location to a substance, e.g., SF6, having an electron-donating constituent so as to generate a substantially disordered surface layer (i.e., a microstructured layer) that incorporates a concentration of that electron-donating constituent, e.g., sulfur. The substrate is also annealed at an elevated temperature and for a duration selected to enhance the charge carrier density in the surface layer. For example, the substrate can be annealed at a temperature in a range of about 700 K to about 900 K. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/950248 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/95 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354809 | Yuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumi Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hao-Chih Yuan (Madison, Wisconsin); Guogong Wang (Madison, Wisconsin); Mark A. Eriksson (Madison, Wisconsin); Paul G. Evans (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Zhenqiang Ma (Middleton, Wisconsin) |
| ABSTRACT | This invention provides methods for fabricating thin film electronic devices with both front- and backside processing capabilities. Using these methods, high temperature processing steps may be carried out during both frontside and backside processing. The methods are well-suited for fabricating back-gate and double-gate field effect transistors, double-sided bipolar transistors and 3D integrated circuits. |
| FILED | Monday, February 13, 2006 |
| APPL NO | 11/276065 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355019 | Backer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SibTech, Inc. (Newington, Connecticut) |
| INVENTOR(S) | Marina V. Backer (W. Simsbury, Connecticut); Joseph M. Backer (W. Simsbury, Connecticut) |
| ABSTRACT | The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety bound to the targeting moiety; the biological conjugate having a covalent bond between the thiol group of SEQ ID NO:2 and a functional group in the binding moiety. The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety that comprises an adapter protein, the adapter protein having a thiol group; the biological conjugate having a disulfide bond between the thiol group of SEQ ID NO:2 and the thiol group of the adapter protein. The present invention is also directed to biological sequences employed in the above biological conjugates, as well as pharmaceutical preparations and methods using the above biological conjugates. |
| FILED | Friday, March 18, 2005 |
| APPL NO | 11/083508 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/399 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355072 | Landis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Clark R. Landis (Madison, Wisconsin); Wiechang Jin (Madison, Wisconsin); Jonathan S. Owen (Pasadena, California); Thomas P. Clark (Madison, Wisconsin) |
| ABSTRACT | Transition metal complexes include a diazaphosphacycle of formula III and a transition metal. The phosphorus atom of the diazaphosphacycle is bonded to the transition metal and the diazaphosphacycle of formula III has the following structure where the variables have the values set forth herein. |
| FILED | Thursday, February 26, 2004 |
| APPL NO | 10/787554 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 564/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355073 | Landis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Clark R. Landis (Madison, Wisconsin); Wiechang Jin (Madison, Wisconsin); Jonathan S. Owen (Pasadena, California); Thomas P. Clark (Madison, Wisconsin) |
| ABSTRACT | A diazaphosphacycle may be synthesized by reacting a phosphine with a diimine and optionally one or more equivalents of an acid halide, a sulfonyl halide, a phosphoryl halide, or an acid anhydride in the substantial absence of O2 to form the diazaphosphacycle. The phosphine has the formula R1—PH2 where R1 is a substituted or unsubstituted aryl group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted cycloalkyl group, or a substituted or unsubstituted ferrocenyl group. |
| FILED | Thursday, February 26, 2004 |
| APPL NO | 10/787555 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 564/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355074 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Jeffery T. Davis (College Park, Maryland); Vladimir Sidorov (Richmond, Virginia); Frank W. Kotch (New Phila., Pennsylvania) |
| ABSTRACT | A compound containing at least two aromatic rings covalently bonded together, with each aromatic ring containing at least one oxyacetamide-based side chain, the compound being capable of forming a chloride ion channel across a lipid bilayer, and transporting chloride ion across the lipid bilayer. |
| FILED | Thursday, February 05, 2004 |
| APPL NO | 10/771414 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355075 | Sithambaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Shanthakumar Sithambaram (Storrs, Connecticut); Young-Chan Son (Storrs, Connecticut); Steven L. Suib (Storrs, Connecticut) |
| ABSTRACT | A method for forming an imine comprises reacting a first reactant comprising a hydroxyl functionality, a carbonyl functionality, or both a hydroxyl functionality and a carbonyl functionality with a second reactant having an amine functionality in the presence of ordered porous manganese-based octahedral molecular sieves and an oxygen containing gas at a temperature and for a time sufficient for the imine to be produced. |
| FILED | Friday, June 16, 2006 |
| APPL NO | 11/424688 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/271 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355216 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peidong Yang (Berkeley, California); Rongrui He (El Cerrito, California); Joshua Goldberger (Berkeley, California); Rong Fan (El Cerrito, California); Yiying Wu (Albany, California); Deyu Li (Albany, California); Arun Majumdar (Orinda, California) |
| ABSTRACT | Fluidic nanotube devices are described in which a hydrophilic, non-carbon nanotube, has its ends fluidly coupled to reservoirs. Source and drain contacts are connected to opposing ends of the nanotube, or within each reservoir near the opening of the nanotube. The passage of molecular species can be sensed by measuring current flow (source-drain, ionic, or combination). The tube interior can be functionalized by joining binding molecules so that different molecular species can be sensed by detecting current changes. The nanotube may be a semiconductor, wherein a tubular transistor is formed. A gate electrode can be attached between source and drain to control current flow and ionic flow. By way of example an electrophoretic array embodiment is described, integrating MEMs switches. A variety of applications are described, such as: nanopores, nanocapillary devices, nanoelectrophoretic, DNA sequence detectors, immunosensors, thermoelectric devices, photonic devices, nanoscale fluidic bioseparators, imaging devices, and so forth. |
| FILED | Thursday, April 08, 2004 |
| APPL NO | 10/822148 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355720 | Carr |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Dustin W. Carr (Albuquerque, New Mexico) |
| ABSTRACT | An optical displacement sensor is disclosed which uses a vertical-cavity surface-emitting laser (VCSEL) coupled to an optical cavity formed by a moveable membrane and an output mirror of the VCSEL. This arrangement renders the lasing characteristics of the VCSEL sensitive to any movement of the membrane produced by sound, vibrations, pressure changes, acceleration, etc. Some embodiments of the optical displacement sensor can further include a light-reflective diffractive lens located on the membrane or adjacent to the VCSEL to control the amount of lasing light coupled back into the VCSEL. A photodetector detects a portion of the lasing light from the VCSEL to provide an electrical output signal for the optical displacement sensor which varies with the movement of the membrane. |
| FILED | Tuesday, December 20, 2005 |
| APPL NO | 11/314335 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/498 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355986 | Vanderveen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Livermore, California) |
| INVENTOR(S) | Keith B. Vanderveen (Tracy, California); Edward B. Talbot (Livermore, California); Laurence E. Mayer (Davis, California) |
| ABSTRACT | Nodes in a network having a plurality of nodes establish communication links with other nodes using available transmission media, as the ability to establish such links becomes available and desirable. The nodes predict when existing communications links will fail, become overloaded or otherwise degrade network effectiveness and act to establish substitute or additional links before the node's ability to communicate with the other nodes on the network is adversely affected. A node stores network topology information and programmed link establishment rules and criteria. The node evaluates characteristics that predict existing links with other nodes becoming unavailable or degraded. The node then determines whether it can form a communication link with a substitute node, in order to maintain connectivity with the network. When changing its communication links, a node broadcasts that information to the network. Other nodes update their stored topology information and consider the updated topology when establishing new communications links for themselves. |
| FILED | Tuesday, October 22, 2002 |
| APPL NO | 10/277141 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Multiplex communications 370/255 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07354505 | Loloee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Reza Loloee (Okemos, Michigan) |
| ABSTRACT | An epitaxial Ni3FeN film with unique magnetic properties such as single magnetic domain (even in a large scale 0.5″×0.5″), which rotates coherently in response to the desired switching field with a very sharp transition is described. The magnetic hysteresis loop of this new magnetic nitride is close to the perfect ideal square with the same value of saturation magnetization, remnant magnetization, and magnetization right before switching (domain reversal). The switching field is tunable which make this material more attractive for magneto-resistive devices such as MRAM's, read heads and magnetic sensors. |
| FILED | Wednesday, August 25, 2004 |
| APPL NO | 10/925815 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/192.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354563 | Smalley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard E. Smalley (Houston, Texas); Daniel T. Colbert (Houston, Texas); Hongjie Dai (Sunnyvale, California); Jie Liu (Chapel Hill, North Carolina); Andrew G. Rinzler (Newberry, Florida); Jason H. Hafner (Houston, Texas); Ken Smith (Katy, Texas); Ting Guo (Davis, California); Pavel Nikolaev (Houston, Texas); Andreas Thess (Kusterdingen, Germany) |
| ABSTRACT | This invention relates generally to a fullerene nanotube purification process and more particularly to a purification process that comprises heating the fullerene nanotube-containing felt under oxidizing conditions to remove the amorphous carbon deposits and other contaminating materials. In a preferred mode of this purification procedure, the felt is heated in an aqueous solution of an inorganic oxidant, such as nitric acid, a mixture of hydrogen peroxide and sulfuric acid, or a potassium permanganate. Preferably, fullerene nanotube-containing felts are refluxed in an aqueous solution of an oxidizing acid at a concentration high enough to etch away amorphous carbon deposits within a practical time frame, but not so high that the fullerene nanotube material will be etched to a significant degree. When material having a high proportion of fullerene nanotubes is purified, the preparation produced will be enriched in fullerene nanotubes, so that the fullerene nanotubes are substantially free of other material. |
| FILED | Tuesday, August 22, 2006 |
| APPL NO | 11/507960 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354659 | Duckham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Reactive Nanotechnologies, Inc. (Hunt Valley, Maryland) |
| INVENTOR(S) | Alan Duckham (Baltimore, Maryland); Jesse E. Newson (Cockeysville, Maryland); Michael V. Brown (Timonium, Maryland); Timothy Ryan Rude (Baltimore, Maryland); Omar Knio (Timonium, Maryland); Ellen M. Heian (Cockeysvile, Maryland); Jai S. Subramanian (Lutherville-Timonium, Maryland) |
| ABSTRACT | A method for joining component bodies of material over bonding regions of large dimensions by disposing a plurality of substantially contiguous sheets of reactive composite materials between the bodies and adjacent sheets of fusible material. The contiguous sheets of the reactive composite material are operatively connected by an ignitable bridging material so that an igniting reaction in one sheet will cause an igniting reaction in the other. An application of uniform pressure and an ignition of one or more of the contiguous sheets of reactive composite material causes an exothermic thermal reaction to propagate through the bonding region, fusing any adjacent sheets of fusible material and forming a bond between the component bodies. |
| FILED | Thursday, March 30, 2006 |
| APPL NO | 11/393055 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/612 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354809 | Yuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumi Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hao-Chih Yuan (Madison, Wisconsin); Guogong Wang (Madison, Wisconsin); Mark A. Eriksson (Madison, Wisconsin); Paul G. Evans (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Zhenqiang Ma (Middleton, Wisconsin) |
| ABSTRACT | This invention provides methods for fabricating thin film electronic devices with both front- and backside processing capabilities. Using these methods, high temperature processing steps may be carried out during both frontside and backside processing. The methods are well-suited for fabricating back-gate and double-gate field effect transistors, double-sided bipolar transistors and 3D integrated circuits. |
| FILED | Monday, February 13, 2006 |
| APPL NO | 11/276065 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354993 | King et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Glenn F. King (St Lucia, QLD 4067, Australia); Brianna Sollod McFarland (Fenton, Missouri); Graham Michael Nicholson (Sydney NSW 2067, Australia); Simon Joseph Gunning (Abbortsford, NSW 2046, Australia) |
| ABSTRACT | The invention relates to isolated insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Methods of treating insects, insect larvae, and plants with the insecticidal polypeptides are also described. |
| FILED | Friday, November 04, 2005 |
| APPL NO | 11/267815 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355216 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peidong Yang (Berkeley, California); Rongrui He (El Cerrito, California); Joshua Goldberger (Berkeley, California); Rong Fan (El Cerrito, California); Yiying Wu (Albany, California); Deyu Li (Albany, California); Arun Majumdar (Orinda, California) |
| ABSTRACT | Fluidic nanotube devices are described in which a hydrophilic, non-carbon nanotube, has its ends fluidly coupled to reservoirs. Source and drain contacts are connected to opposing ends of the nanotube, or within each reservoir near the opening of the nanotube. The passage of molecular species can be sensed by measuring current flow (source-drain, ionic, or combination). The tube interior can be functionalized by joining binding molecules so that different molecular species can be sensed by detecting current changes. The nanotube may be a semiconductor, wherein a tubular transistor is formed. A gate electrode can be attached between source and drain to control current flow and ionic flow. By way of example an electrophoretic array embodiment is described, integrating MEMs switches. A variety of applications are described, such as: nanopores, nanocapillary devices, nanoelectrophoretic, DNA sequence detectors, immunosensors, thermoelectric devices, photonic devices, nanoscale fluidic bioseparators, imaging devices, and so forth. |
| FILED | Thursday, April 08, 2004 |
| APPL NO | 10/822148 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355597 | Laidlaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Brown University Research Foundation (Providence, Rhode Island) |
| INVENTOR(S) | David H Laidlaw (Barrington, Rhode Island); Andreas Wenger (Los Angeles, California) |
| ABSTRACT | Described is a system, method and computer program product for rendering volumetric multivalued primary data. The system includes a rendering engine having an input coupled to a source of multivalued primary data and an output coupled to a display. The rendering engine includes a data processor for calculating additional data values from the primary data, deriving at least one visual representation from the primary data and the additional data values, and mapping the derived visual representation through transfer functions to hardware primitives for volumetrically rendering the derived visual representation to provide a visualization. The system further includes a user interface for interacting with the visualization. The source of primary data can be a magnetic resonance imaging system, and the primary data may be a multivalued combination obtained from T1 weighted data, T2 weighted data, diffusion data, velocity data, magnetization transfer data, perfusion data, data derived from other imaging modalities (e.g., PET), and simulation data. The primary data can be diffusion tensor data generated by the MRI system from tissue, and the data processor operates to identify directed diffusion paths and to render the directed diffusion paths as thread-like structures. Indications of at least flowing blood velocity and vorticity can also be rendered from MRI data or from simulations. |
| FILED | Tuesday, May 06, 2003 |
| APPL NO | 10/431130 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356364 | Bullock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Hawai'i (Honolulu, Hawaii) |
| INVENTOR(S) | Audra M. Bullock (Kaneohe, Hawaii); Daniel F. Ling (Honolulu, Hawaii); John Roeder (Mililani, Hawaii); Hao Chih Ho (Honolulu, Hawaii); Anita Schorlemmer (Honolulu, Hawaii) |
| ABSTRACT | A device for monitoring the concentration level of a constituent in tissue or a body fluid sample, such as glucose concentration in blood, has a laser light source which is modulated about a center emission frequency to probe the absorption spectrum of the constituent being monitored, a laser driver circuit for tuning and modulating the laser light, a photodetector for detecting light from the laser light source transmitted through the sample as the modulation frequency of the laser is tuned, and a demodulator for demodulating the transmitted light and detecting variations in magnitude at harmonics of the modulation frequency to assess the concentration level of that constituent. The device utilizes short-wavelength near-infrared laser light to monitor blood glucose levels, and could also be used for drug screening and diagnosis of other medical conditions as well. In one embodiment, the device is used to monitor blood glucose level externally from the body and non-invasively by trans-illumination through a thin layer of skin, without the need for physical penetration of the skin. In another embodiment, the device is used as an intravenous sensor deployed through a catheter, and its output can be used to control an insulin pump to stabilize the patient's blood glucose levels. |
| FILED | Friday, January 21, 2005 |
| APPL NO | 11/041168 |
| ART UNIT | 3768 — Optics |
| CURRENT CPC | Surgery 6/310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356449 | Hashash |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Youssef Hashash (Urbana, Illinois) |
| ABSTRACT | An embodiment of a method and a program product of the invention has steps of selecting a model from a plurality of models in a model library, with at least one of the models being a constitutive model. Load data and load path data are input to the model to generate model output. The output is then displayed in a graphical format. |
| FILED | Tuesday, April 16, 2002 |
| APPL NO | 10/123357 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356672 | Vahid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Frank Vahid (Corona, California); Roman Lev Lysecky (Hemet, California); Gregory Michael Stitt (San Bernardino, California) |
| ABSTRACT | A warp processor includes a microprocessor, profiler, dynamic partitioning module, and warp configurable logic architecture. The warp processor initially executes a binary for an application entirely on the microprocessor, the profiler monitors the execution of the binary to detect its critical code regions, and the dynamic partitioning module partitions the binary into critical and non-critical code regions, re-implements the critical code regions in the configurable logic, and then transforms the binary so that it accesses the configurable logic rather than execute the critical code regions. |
| FILED | Friday, May 28, 2004 |
| APPL NO | 10/856062 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/37 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356747 | Hsiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Michael S. Hsiao (Blacksburg, Virginia); Kameshwar Chandrasekar (Blacksburg, Virginia) |
| ABSTRACT | An all solutions automatic test pattern generation (ATPG) engine method uses a decision selection heuristic that makes use of the “connectivity of gates” in the circuit in order to obtain a compact solution-set. The “symmetry in search-states” is analyzed using a “Success-Driven Learning” technique which is extended to prune conflict sub-spaces. A metric is used to determine the use of learnt information a priori, which information is stored and used efficiently during “success driven learning”. |
| FILED | Tuesday, August 02, 2005 |
| APPL NO | 11/194543 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/738 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07353768 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Jack A. Jones (Los Angeles, California); Yi Chao (Arcadia, California) |
| ABSTRACT | An underwater vehicle includes a shaft with a propeller disposed thereon; a generator/motor having a stator and a rotor, the rotor being operable to rotate with the propeller; at least one energy storage device connected to the generator/motor; and a controller for setting the generator/motor in a charge mode, a propulsion mode and an idle mode. |
| FILED | Monday, July 10, 2006 |
| APPL NO | 11/456441 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/337 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355389 | Rieger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Ryan W. Rieger (Brooklyn Center, Minnesota); Hong Wan (Plymouth, Minnesota); Michael L. Freeman (Woodbury, Minnesota) |
| ABSTRACT | Systems and methods for determining linear position are disclosed. An example system includes a magnet with first and second magnetic poles. The first and second magnetic poles define an axis of the magnet. The system also includes a magnetoresistive sensor comprising a magnetoresistive sensor structure. The magnetoresistive sensor structure defines a plane that, in the system, is oriented out-of-plane with the axis of the magnet. In operation, the magnet travels, with respect to the magnetoresistive sensor, along a substantially linear path of travel that is substantially parallel to the plane defined by the sensor structure, such that the sensor operates in a saturation mode when the magnet is located along a given portion of the path of travel. When operating in the saturation mode, the magnetoresistive sensor produces an electrical signal that corresponds with a linear position of the magnet along the given portion of the path of travel. |
| FILED | Tuesday, November 01, 2005 |
| APPL NO | 11/265409 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/207.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355508 | Mian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Electronic Machines Corp. (Albany, New York) |
| INVENTOR(S) | Zahid F. Mian (Loudonville, New York); Ryk E. Spoor (Troy, New York); Ronald W. Gamache (East Greenbush, New York) |
| ABSTRACT | An improved system for monitoring an area, and in particular a public area such as a passenger area of a vehicle. Various types of sensing devices and analysis solutions are incorporated and the results combined to enable the monitoring system to operate in an intelligent manner. To this extent, the monitoring system can monitor and confirm the identification of individuals as well as numerous events that may occur within the monitored area. Further, the invention can determine one or more actions to be taken in response to an event, and perform the action(s) automatically without intervention from a user. As a result, the invention provides a solution that can autonomously monitor an area, requiring minimal oversight from a user. |
| FILED | Friday, December 03, 2004 |
| APPL NO | 11/003039 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/426.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07354729 | Rich |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | HemoGenix, Inc. (Colorado Springs, Colorado) |
| INVENTOR(S) | Ivan N. Rich (Columbia, South Carolina) |
| ABSTRACT | The present invention relates generally to high-throughput assay methods that determine the proliferative status of hematopoietic stem and progenitor cells. The present invention further relates to high-throughput assays for screening compounds that modulate the growth of hematopoietic stem and progenitor cells and for identifying subpopulations thereof that are suitable for transplantation. The assay of the present invention is particularly useful for quality control and monitoring of the growth potential in the stem cell transplant setting and would provide improved control over the reconstitution phase of transplanted cells. |
| FILED | Tuesday, January 29, 2002 |
| APPL NO | 10/059521 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354730 | Rich |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | HemoGenix, Inc. (Colorado Springs, Colorado) |
| INVENTOR(S) | Ivan N. Rich (Colorado Springs, Colorado) |
| ABSTRACT | The present invention relates generally to kits that provide reagent mixes and instructions for the use thereof, in performing high-throughput assay methods that determine the proliferative status of isolated target cell populations. The methods measure the luminescent output derived from the intracellular ATP content of incubated target cells, and correlate the luminescence with the proliferative status of the cells. The present invention further relates to kits that provide reagent mixes and instructions for high-throughput assays methods for screening compounds that may modulate the proliferative status of a target cell population. The kits of the present invention and methods therein described may be used for determining the proliferative status of any isolated cell line or type. The kits and methods of the present invention address the need for rapid assays that determine the proliferative status of isolated hematopoietic stem and progenitor cells and of subpopulations of differentiated cells thereof. |
| FILED | Thursday, August 21, 2003 |
| APPL NO | 10/645077 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07356444 | Blemel |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth Gerald Blemel (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus providing a means for assessment of the integrity of insulated conduits, harnesses, cables, pipelines and other interconnection systems constructed with integral sensitized media, discrete sensors, and electronics providing a means for transforming sensed data into information and a means for communicating information for the purpose of understanding the location, degree and risk of damage and deterioration, and the probable causes thereof. |
| FILED | Monday, June 26, 2006 |
| APPL NO | 11/474967 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07354611 | Ferkovich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Stephen M. Ferkovich (Gainesville, Florida); Jeffrey Shapiro (Gainesville, Florida) |
| ABSTRACT | A new protein supplement for insect rearing contains extracts of insect eggs or cultured insect egg embryonic cell lines from insects such as Plodia interpunctella and Ephestia kuehniella Zeller, etc., to increase the fecundity of insects reared for biocontrol. |
| FILED | Wednesday, November 26, 2003 |
| APPL NO | 10/721881 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Food or edible material: Processes, compositions, and products 426/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354904 | Stern et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Norman J. Stern (Athens, Georgia); Edward A. Svetoch (Serpukhov, Russian Federation); Boris V. Eruslanov (Serpukhov, Russian Federation); Vladimir V. Perelygin (Serpukhov, Russian Federation); Vladimir P. Levchuk (Serpukhov, Russian Federation) |
| ABSTRACT | Novel peptides produced by bacteriocin-producing bacteria stimulate the production of bacteriocins in vitro. The producer bacteria are cultured in the presence of a novel inducer bacteria and a peptide having a carboxy terminal sequence of VKGLT in order to achieve an increase in bacteriocin production. |
| FILED | Thursday, December 08, 2005 |
| APPL NO | 11/297841 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07354545 | Eshraghi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Microcell Corporation (Raleigh, North Carolina) |
| INVENTOR(S) | Ray R. Eshraghi (Cary, North Carolina); Martin E. Ketterer (Apex, North Carolina); Yongchao Si (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention relates to a substrate-supported process for continuous and automated manufacturing of microfibrous fuel cells and other electrochemical cells. Specifically, a removable substrate layer is formed around an inner current collector, followed by sequentially coating multiple structure layers, such as the inner catalyst layer, the membrane separator, and the outer catalyst layer, over such removable substrate layer, and subsequent removing such removable substrate layer, so as to form a lumen around the inner current collector, to allow passage of fluid therethrough. The removable substrate layer preferably comprises a water-soluble polymer, such as polyvinyl pyrrolidone (PVP), polyvinyl alcohol (PVA), or polyethylene glycol (PEG). |
| FILED | Tuesday, December 23, 2003 |
| APPL NO | 10/744203 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/313 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355058 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Albemarle Corporation (Richmond, Virginia) |
| INVENTOR(S) | Lubin Luo (Baton Rouge, Louisiana); Samuel A. Sangokoya (Baton Rouge, Louisiana); Steven P. Diefenbach (Baton Rouge, Louisiana); Jamie R. Strickler (Baton Rouge, Louisiana); Christopher G. Bauch (Prairieville, Louisiana) |
| ABSTRACT | Novel haloaluminoxane compositions have been formed. The halogen is fluorine, chlorine, and/or bromine, and the amount of halogen atoms present in said composition is in the range of about 0.5 mole % to about 15 mole % relative to aluminum atoms. Processes for producing haloaluminoxane compositions are also provided. |
| FILED | Friday, August 25, 2006 |
| APPL NO | 11/509938 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/179 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07354711 | Macfarlane |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); The Department of Veterans Affairs, as represented by the Secretary of United States of America (Washington, District of Columbia) |
| INVENTOR(S) | Donald E. Macfarlane (Iowa City, Iowa) |
| ABSTRACT | The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhibiting immunostimulatory DNA-induced immune responses. |
| FILED | Friday, January 03, 2003 |
| APPL NO | 10/336635 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07354897 | Gilbert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Gary E. Gilbert (Winchester, Massachusetts); Jialin Shi (Newton, Massachusetts) |
| ABSTRACT | A method and composition for inhibiting or slowing blood coagulation includes lactadherin, a fragment of lactadherin, a functional equivalent of lactadherin, or a functional equivalent of a fragment of lactadherin. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/516450 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 07356454 | Sakane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UD Technology Corporation (Newark, Delaware) |
| INVENTOR(S) | Hirofumi Sakane (Newark, Delaware); Levent Yakay (Elkton, Maryland); Vishal Karna (Newark, Delaware); Clement Leung (Reston, Virginia); Guang R. Gao (Newark, Delaware) |
| ABSTRACT | A method for emulating a logic circuit having at least one set of identical logic modules is disclosed. Each logic module in a set has logic elements and memory elements that store a module state of that logic module. The logic circuit is emulated by extracting a logic module from a set of identical logic modules, translating the extracted logic module for iterative representation of the module state of each of the logic modules with a single instance of the logic elements, and configuring a logic device with the translated logic module to emulate the logic circuit. |
| FILED | Monday, October 18, 2004 |
| APPL NO | 10/967814 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07356824 | Stickler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Vantresa Stickler (Annapolis, Maryland); Lonie Pento (Staten Island, New York); Diane Ditzler (Falls Church, Virginia) |
| ABSTRACT | A shared services hub is provided that allows a software application that is related to a given postal product, to access, translate, and communicate information related to a second postal service or module. A customer accessing the Postal Service website for a particular postal product, such as for example the Parcel Post or Global Express Mail, can then access further information. A communications link is established from the software application, through a shared services hub, to a software module. Information on the software module, such as for example, postage, shipping rules, or tracking information, is then translated and communicated through the software application in a compatible format. The shared services hub thus allows a plurality of information on software modules to be accessed through a plurality of product applications, regardless of communication protocols used by the software modules. |
| FILED | Wednesday, June 04, 2003 |
| APPL NO | 10/454227 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07353598 | Craig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Alien Technology Corporation (Morgan Hill, California) |
| INVENTOR(S) | Gordon S. W. Craig (Palo Alto, California); Ali A. Tootoonchi (San Jose, California); Randolph W. Eisenhardt (Fargo, North Dakota); Scott Herrmann (Gahanna, Ohio); Mark A. Hadley (Newark, California); Paul S. Drzaic (Morgan Hill, California) |
| ABSTRACT | Methods and apparatuses for an electronic assembly. A material is selectively printed on a web substrate at one or more selected areas. The web substrate includes a plurality of functional components having integrated circuits. A local printing system equipped with a print head that dispenses the selected material is used to print. The print head is coupled to a guidance system capable of registering an alignment feature on the web substrate. |
| FILED | Monday, November 07, 2005 |
| APPL NO | 11/268837 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/846 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07355081 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The University of Rochester Medical Center (Rochester, New York); Androscience Corporation (San Diego, California) |
| INVENTOR(S) | Kuo-Hsiung Lee (Chapel Hill, North Carolina); Li Lin (Chapel Hill, North Carolina); Charles C-Y Shih (Solana Beach, California); Ching-Yuan Su (San Diego, California); Junko Ishida (Tokyo, Japan); Hironori Ohtsu (Matsubara, Japan); Hui-Kang Wang (San Diego, California); Hideji Itokawa (Chapel Hill, North Carolina); Chawnshang Chang (Pittsford, New York) |
| ABSTRACT | The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/966723 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/36 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 08, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080408.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page