FedInvent™ Patents
Patent Details for Tuesday, April 29, 2008
This page was updated on Monday, March 27, 2023 at 12:57 AM GMT
Department of Health and Human Services (HHS)
| US 07364543 | Yang et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Changhuei Yang (Pasadena, California); Jigang Wu (Pasadena, California) |
| ABSTRACT | Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as to image a conical scan volume when light is provided by the source. Reflected light from a sample under investigation is collected by the fiber and analyzed by an imaging system. Such probes may be very compact, e.g., having a diameter 1 mm or less, and are advantageous for use in minimally invasive surgical procedures. A fluid medium can be introduced between two lens elements at the distal end of the probe to switch a mode from side viewing to forward viewing. |
| FILED | Tuesday, September 26, 2006 |
| APPL NO | 11/535427 |
| ART UNIT | 3739 — Optics |
| CURRENT CPC | Surgery 6/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364719 | Cuttitta et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Frank Cuttitta (Adamstown, Maryland); Alfredo Martinez (Bethesda, Maryland); William G. Stetler-Stevenson (Kensington, Maryland); Edward J. Unsworth (Kensington, Maryland); Juan M. Saavedra (Bethesda, Maryland) |
| ABSTRACT | Methods and compounds are described for regulating blood pressure in a subject. Specific embodiments are methods for reversing vasodilation of blood vessels, by administering to a subject a therapeutically effective amount peptide AM(11-22). The vasoconstrictor can be used for a variety of purposes, including hemostasis or the treatment of shock, for example vasodilatory shock syndromes such as septic shock. Other specific embodiments are methods for reversing vasoconstriction of blood vessels, by administering to a subject a therapeutically effect amount of an inhibitor of AM(11-22), sufficient to reduce hypertension in the subject. Compounds and pharmaceutical compositions are also provided, as are kits. |
| FILED | Friday, October 03, 2003 |
| APPL NO | 10/529118 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364733 | Godfrey et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); Becton Dickinson and Company (Franklin Lakes, New Jersey) |
| INVENTOR(S) | Wayne Godfrey (Woodside, California); David Buck (Half Moon Bay, California); Edgar G. Engleman (Atherton, California) |
| ABSTRACT | The invention provides purified ACT-4 receptor polypeptides, antibodies against these polypeptides and nucleic acids encoding ACT-4 receptor polypeptides. Also provided are methods of diagnosis and treatment using the same. ACT-4 receptors are preferentially expressed on the surface of activated CD4+ T-cells. ACT-4 receptors are usually expressed at low levels on the surface of activated CD8+ cells, and are usually substantially absent on resting T-cells, and on monocytes and B-cells (resting or activated). An exemplary ACT-4 receptor, termed ACT-4-h-1, has a signal sequence, an extracellular domain comprising three disulfide-bonded intrachain loops, a transmembrane domain, and an intracellular domain. |
| FILED | Monday, March 22, 2004 |
| APPL NO | 10/805377 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/137.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364740 | Behr et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Marcel Behr (Montreal, Canada); Peter Small (Seattle, Washington); Gary Schoolnik (Stanford, California); Michael A. Wilson (Bethesda, Maryland) |
| ABSTRACT | Specific genetic deletion are identified in mycobacteria isolates, including variations in the M. tuberculosis genome sequence between isolates, and numerous deletion present in BCG as compared to M. tb. These deletions are used as markers to distinguish between pathogenic and avirulent strains, and as a marker for particular M. tb isolates. Deletions specific to vaccine strains of BCG are useful in determining whether a positive tuberculin skin test is indicative of actual tuberculosis infection. The deleted sequences may be re-introduced into BCG to improve the efficacy of vaccination. Alternatively, the genetic sequence that corresponds to the deletion(s) are deleted from M. bovis or M. tuberculosis to attenuate the pathogenic bacteria. |
| FILED | Wednesday, June 01, 2005 |
| APPL NO | 11/143401 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364757 | Otterbein et al. |
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| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Leo E. Otterbein (New Kensington, Pennsylvania); Augustine M. K. Choi (Pittsburgh, Pennsylvania); Fritz H. Bach (Manchester-by-the-sea, Massachusetts); Brian Zuckerbraun (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient. |
| FILED | Thursday, February 13, 2003 |
| APPL NO | 10/367277 |
| ART UNIT | 1614 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/699 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364853 | Bacher et al. |
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| ASSIGNEE(S) | Promega Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Jeffery W. Bacher (Madison, Wisconsin); Laura Flanagan (Fort Atkinson, Wisconsin); Nadine Nassif (Madison, Wisconsin) |
| ABSTRACT | Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits of the present invention can be used to detect or diagnose diseases associated with microsatellite instability, such as certain types of cancer. |
| FILED | Tuesday, January 18, 2005 |
| APPL NO | 11/037321 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364858 | Barany et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Francis Barany (New York, New York); Matthew Lubin (Rye Brook, New York); George Barany (Falcon Heights, Minnesota); Robert P. Hammer (Baton Rouge, Louisiana) |
| ABSTRACT | The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain reaction (PCR) mixture, detecting the amplified ligation product, and identifying the target nucleotide sequence. Such coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence differences. |
| FILED | Tuesday, October 31, 2006 |
| APPL NO | 11/590529 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364868 | Ruppert et al. |
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| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | J. Michael Ruppert (Birmingham, Alabama); Jeffrey Allen Engler (Birmingham, Alabama) |
| ABSTRACT | The present invention proivdes methods of identifying new carcinoma oncogenes or analyzing functions of known carcinoma oncogenes by transformation of RK3E cells. Also provided are methods of using nuclear localization of Krüppel-like factor 4 (KLF4, or termed Gut-Enriched Krüppel-Like Factor, GKLF) as a marker and prognostic factor for aggressive early-stage breast carcinoma. |
| FILED | Wednesday, February 11, 2004 |
| APPL NO | 10/776133 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364869 | Nixon et al. |
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| ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Douglas Nixon (San Francisco, California); Barbara Shacklett (Davis, California); Wim Jennes (Antwerpen, Belgium); Luc Kestens (Antwerpen, Belgium) |
| ABSTRACT | The present invention provides a method of detecting antigen-specific T lymphocytes in a sample. The present invention further provides kits and systems for detecting antigen-specific T lymphocytes in a sample. |
| FILED | Monday, July 19, 2004 |
| APPL NO | 10/895239 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364882 | Iwata-Reuyl et al. |
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| ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Portland State University (Portland, Oregon); Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Dirk Iwata-Reuyl (Corbett, Oregon); Valérie de Crecy-Lagard (Gainesville, Florida); Steven G. Van Lanen (Madison, Wisconsin) |
| ABSTRACT | A new class of enzymes that catalyze the conversion of a nitrile containing compound to the corresponding amine (such as a primary amine) are disclosed. Such enzymes are referred to herein as nitrile oxido-reductases. Methods of using the enzymes to reduce a nitrile to a amine, for example in vitro or in vivo, are provided. Such methods provide the first biocatalysis method for reducing nitrites to amines, and provides an alternative to currently used methods, which generally utilize harsh reaction conditions and the production of hazardous waste. While the hydrolysis of nitrites to amides and carboxylic acids via biocatalysis has found extensive use in industry, the lack of a known nitrile oxido-reductase has precluded the application of biocatalysis to nitrile reduction. |
| FILED | Monday, September 26, 2005 |
| APPL NO | 11/235933 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364886 | Hasenbank et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Melissa S. Hasenbank (Seattle, Washington); Elain S. Fu (Seattle, Washington); Paul Yager (Seattle, Washington) |
| ABSTRACT | The invention provides a method, apparatus and system for detecting electrochemical oxidoreduction activity mediated by a redox enzyme at a site remote from the enzyme. In one embodiment, the method comprises immobilizing the redox enzyme on a first region of a conductive surface and contacting a substrate capable of producing a detectable signal upon oxidation or reduction with a second region of the conductive surface. The second region is electrically coupled with the first region and the redox enzyme is not present in the second region. The method further comprises exposing the immobilized redox enzyme to conditions that effect oxidation or reduction of the enzyme, and detecting oxidation or reduction of the substrate at the second region. The invention can be adapted for detecting a plurality of analytes. |
| FILED | Tuesday, February 28, 2006 |
| APPL NO | 11/364436 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/174 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364908 | Curran et al. |
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| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Fluorous Technologies Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Dennis P. Curran (Pittsburgh, Pennsylvania); Masato Matsugi (Pittsburgh, Pennsylvania); Marvin S. Yu (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of separating at least a first non-fluorous compound from a mixture of compounds including at least the first non-fluorous compound and a second fluorous compound includes: charging the of compounds to a non-fluorous solid (stationary) phase and eluting with a fluorous eluting fluid (mobile phase). In one embodiment, the non-fluorous solid phase is polar in nature. The method can further include a second phase elution with a suitable organic solvent. A method conducting a chemical reaction, includes: mixing at least a first fluorous compound and a second compound, the first fluorous compound differing in fluorous nature from the second compound; exposing the first mixture to conditions to convert at least one of the first fluorous compound and the second compound to give a second mixture containing at least a third compound, charging the second mixture to a non-fluorous solid phase; and eluting with a fluorous fluid. |
| FILED | Thursday, June 17, 2004 |
| APPL NO | 10/870514 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365050 | Messing et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert O. Messing (Foster City, California); Philip M. Newton (San Francisco, California) |
| ABSTRACT | The present invention provides a method of reducing or preventing a drug-related effect or behavior in a subject by inhibiting N-type calcium channels. In addition, the invention provides a variety of prescreening and screening methods aimed at identifying agents that modulate a drug-related effect or behavior. These methods involve assaying test agent binding to N-type calcium channels or channel subunits. Alternatively, test agents can be screened for their ability to alter the level of N-type calcium channels, channel subunit polypeptide or RNA, or the depolarization-induced inward calcium current mediated by these channels. Finally, the invention also provides a diagnostic method that entails measuring one or more of these levels and determining risk for a drug-related effect or behavior based on comparison to the corresponding level for a control population. |
| FILED | Thursday, August 05, 2004 |
| APPL NO | 10/913697 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365054 | Lode et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); EMD Lexigen Research Center Corp. (Billerica, Massachusetts) |
| INVENTOR(S) | Holger N. Lode (Berlin, Germany); Ralph A. Reisfeld (La Jolla, California); David A. Cheresh (Encinitas, California); Stephen D. Gillies (Carlisle, Massachusetts) |
| ABSTRACT | The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response. |
| FILED | Tuesday, September 26, 2006 |
| APPL NO | 11/527029 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365060 | Rokita et al. |
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| ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Steven E. Rokita (Silver Spring, Maryland); Kenneth D. Karlin (Owings Mills, Maryland); Kristi J. Humphreys (Oakland, California); Lei Li (Baltimore, Maryland); Narasimha N. Murthy (Madras, India) |
| ABSTRACT | The present invention is related to a novel method for splitting nucleic acids at specific points on a complementary nucleic acid segment using a dinuclear copper-based compound of Formula I. Additionally, the present invention is related to a novel treatment of cancer, tumors, and cancer cells using a dinuclear copper-based compound of Formula I or a naked ligand of formula II: (Formula I and II). |
| FILED | Tuesday, November 12, 2002 |
| APPL NO | 10/492196 |
| ART UNIT | 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365096 | Kirken et al. |
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| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Robert A. Kirken (Conroe, Texas); Barry D. Kahan (Houston, Texas); Stanislaw M. Stepkowski (Pearland, Texas); Waldemar Priebe (Houston, Texas); Izabela Fokt (Spring, Texas); Szymon Kosinski (Menomonee Falls, Wisconsin) |
| ABSTRACT | Methods are disclosed for inhibiting or disrupting Janus tyrosine kinase 3 (Jak3) dependent function in cells of lymphoid or myeloid origin, especially for blocking proliferation and function of lymphocytes (e.g., T-cells, B-cells). A Mannich base compound, or a derivative or modified compound, is employed which is capable of selectively inhibiting Jak3 while affecting other protein tyrosine kinase activities to a lesser extent or not at all, to provide beneficial effects such as mitigation of transplant rejection and alleviation of allergic responses with fewer side effects than with conventional immunosuppressive agents. |
| FILED | Tuesday, December 09, 2003 |
| APPL NO | 10/731769 |
| ART UNIT | 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/513 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365158 | Huang |
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| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Shi Huang (San Diego, California) |
| ABSTRACT | The invention provides an isolated PR Family Member (PFM) nucleic acid molecule that contains a PFM PR domain nucleotide sequence, a PFM ZF domain nucleotide sequence, or a modification thereof. The invention also provides an isolated PFM nucleic acid molecule that contains a nucleotide sequence that encodes a PFM PR domain polypeptide, or that encodes a PFM ZF domain polypeptide, or that encodes an immunologically equivalent modification thereof. Also provided are isolated PFM oligonucleotides. The invention also provides methods for detecting a PFM nucleic acid molecule in a sample. Further provided is a method of modulating cell growth by expressing an encoded PFM polypeptide in the cell. Also provided is an isolated PFM polypeptide, containing a PFM PR domain amino acid sequence, or a PFM ZF domain amino acid sequence, or a modification thereof. The invention also provides an isolated PFM peptide, containing at least 8 contiguous amino acids of a PFM polypeptide. Also provided is an antibody or antigen binding fragment thereof, which specifically binds a PFM polypeptide. Further provided is a method for detecting PFM polypeptide in a sample, by contacting the sample with a PFM antibody and detecting specifically bound antibody. |
| FILED | Friday, February 28, 2003 |
| APPL NO | 10/377079 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365160 | Negishi et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Masahiko Negishi (Chapel Hill, North Carolina); Akiko Ueda (Durham, North Carolina); Lars C. Pedersen (Chapel Hill, North Carolina); Satoru Kakizaki (Durham, North Carolina); Tatsuya Sueyoshi (Chapel Hill, North Carolina) |
| ABSTRACT | Disclosed are constitutively active nuclear orphan receptors (CAR), which include one or more mutations which decrease the constitutive nature of CAR in vitro. The resulting non-constitutively active nuclear orphan receptors can be used to screen for agents that metabolize xenochemicals and/or steroids. |
| FILED | Wednesday, February 19, 2003 |
| APPL NO | 10/505183 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365169 | Glimcher et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Laurie H. Glimcher (West Newton, Massachusetts); Susanne J. Szabo (Somerville, Massachusetts) |
| ABSTRACT | Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides, e.g., anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including, e.g., methods for detecting T-bet activity in a biological sample. |
| FILED | Wednesday, November 30, 2005 |
| APPL NO | 11/291426 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365181 | Hering et al. |
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| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Thomas M. Hering (Shaker Heights, Ohio); Brian Johnstone (Shaker Heights, Ohio) |
| ABSTRACT | Markers for detecting and staging chondrogenesis in cells are provided. In one aspect the markers are isolated polynucleotides, referred to hereinafter as CZF-1 and CZF-2, and fragments thereof. In one embodiment, the CZF-1 polynucleotide comprises the open reading frame sequence set forth in SEQ ID NO.1. In one embodiment, the CZF-2 polynucleotide comprises the open reading frame sequence set forth in SEQ ID NO. 3. In another aspect the markers are antibodies, which are immunospecific for proteins encoded by CZF-1 or CZF-2. Methods which employ the present markers to identify cells that have begun to differentiate into chondrocytes are provided. The present invention also relates to the CZ-1 protein and the CZ-2 protein and to polynucleotides or oligonucleotides whose sequences are complementary to the coding sequences of CZF-1 or CZF-2, or regions thereof. |
| FILED | Monday, July 21, 2003 |
| APPL NO | 10/623914 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365184 | Jones et al. |
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| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Marcus B. Jones (Rockville, Maryland); Martin J. Blaser (New York, New York); Thomas Wood (Tolland, Connecticut); Dacheng Ren (Ithaca, New York) |
| ABSTRACT | The present invention pertains to the discovery that B. anthracis possesses a luxS gene that encodes a functional LuxS polypeptide, and that B. anthracis synthesizes a functional AI-2 quorum-sensing molecule. The invention provides mutant B. anthracis bacteria lacking the function of the luxS gene, which do not produce a functional AI-2 molecule and have growth defects compared to wild-type B. anthracis. The invention also concerns methods for inhibiting the growth of B. anthracis, or for preventing or treating B. anthracis infection, by inhibiting the activity of the B. anthracis LuxS polypeptide, or by exposure of the B. anthracis to furanone. In particular, the invention concerns the use of furanone, a compound that inhibits AI-2-mediated quorum-sensing, to inhibit the growth of B. anthracis, to inhibit B. anthracis toxin production, particularly that of protective antigen, and to prevent or treat B. anthracis infection. The invention also provides methods to prevent B. anthracis infection, or enhance an immune response to B. anthracis infection, by administering a vaccine comprising a B. anthracis cell in which the luxS gene is mutated. |
| FILED | Monday, April 12, 2004 |
| APPL NO | 10/823396 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365239 | Tsai et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Mindy Tsai (Palo Alto, California); See-Ying Tam (Palo Alto, California); Stephen J. Galli (Portola Valley, California) |
| ABSTRACT | Non-human transgenic animal models and cells derived therefrom are provided for RabGEF1 function. RabGEF1 is a negative regulator of FcεRI-dependent mast cell activation and T cell activation via the T cell receptor and a lack of RabGEF1 results in the development of skin inflammation in vivo. The mast cells derived from such animals exhibit enhanced Ras-mediated signaling and functional responses when activated through high affinity IgE receptors. These cells show significant potentiation of IgE and antigen-dependent secretion of 3 classes of mast cell mediators, providing a useful source of mast cells for screening assays. The animals and cells derived therefrom are also useful for screening biologically active agents that may modulate RabGEF1 function, including therapeutic agents for the treatment of skin disorders, such as eczema, psoriasis, and the like, or for the treatment of other mast cell-associated disorders, including allergic disorders, such as asthma and hay fever, and certain autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. Inhibiting RabGEF1 function may be useful in those conditions in which it is desirable to enhance T cell and/or mast cell function, such as in AIDS or other immune deficiency disorders. |
| FILED | Tuesday, June 21, 2005 |
| APPL NO | 11/158655 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365289 | Wilkes et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Jon Gardner Wilkes (Little Rock, Arkansas); Dan Alexander Buzatu (Little Rock, Arkansas); Dwight Wayne Miller (Whitehall, Arkansas); Alexandru Sorin Biris (Little Rock, Arkansas); Alexandru Radu Biris (Cluj Napoca, Romania); Dan Lupu (Cluj Napoca, Romania); Jerry A. Darsey (Little Rock, Arkansas) |
| ABSTRACT | An apparatus for synthesizing nanostructures. In one embodiment, the apparatus includes a heating device that defines a reaction zone therein and a susceptor made of a ferromagnetic material with a Curie temperature and placed in the reaction zone, where the Curie temperature substantially corresponds to a temperature at which the growth of desired nanostructures occurs and the heating device is capable of heating the susceptor substantially at the Curie temperature. |
| FILED | Wednesday, December 14, 2005 |
| APPL NO | 11/302986 |
| ART UNIT | 3742 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric heating 219/634 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07363765 | Szczesuil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Stephen Szczesuil (Framingham, Massachusetts); Michael J. Holthe (Holliston, Massachusetts) |
| ABSTRACT | Article of footwear includes a sole, an insole overlying the sole, the insole having in a surface thereof a groove having an inlet and outlet in an edge of the insole, the groove winding substantially throughout the length and width of the insole upper surface. A tube is disposed in the groove and extends throughout the length of the groove and has an inlet portion extending from the groove inlet at the edge of the insole and an outlet portion extending from the groove outlet. An upper fixed to the sole has apertures through which extend the tube inlet and outlet portions. |
| FILED | Tuesday, September 20, 2005 |
| APPL NO | 11/231086 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Refrigeration 062/3.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07363862 | Gilliam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jason C. Gilliam (Harvest, Alabama); Darin L. Kielsmeier (Huntsville, Alabama) |
| ABSTRACT | A multi-purpose tandem warhead needing only a single initiation has a casing that forms front, middle and rear portions. A shaped charge is positioned in the rear portion of the casing and a fragmentation charge is positioned in the front portion of the casing. The middle portion between the front and rear portions is an open area that serves as a jet formation region. An impact switch is positioned at the front of the warhead. Upon impact with a target the impact switch sends a detonation signal to a detonator positioned at the rear end of the warhead causing the shaped charge to initiate. Upon the detonation of the rear shaped charge, a high-speed shaped-charge jet forms into the hollow jet formation region, penetrates into and initiates the forward fragmentation charge, and continues through the fragmentation charge. The residual shaped charge jet provides lethality against light armored targets while the fragmentation from the forward charge provides lethality against personnel and other soft targets. |
| FILED | Friday, May 27, 2005 |
| APPL NO | 11/139909 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364692 | Spowart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan E. Spowart (Dayton, Ohio); Benji Maruyama (Yellow Springs, Ohio); Daniel B. Miracle (Bellbrook, Ohio) |
| ABSTRACT | Metal-matrix composites with combinations of physical and mechanical properties desirable for specific applications can be obtained by varying and controlling selected parameters in the material formation processes, particularly by increasing the microstructural homogeneity of the composite, while maintaining a constant mixture ratio or volume fraction. In one embodiment of the invention, a CuSiC composite having increased thermal conductivity is obtained by closely controlling the size of the SiC particles. In another embodiment of the invention, AlSiC composites which exhibit increased ultimate tensile and yield strengths are made by closely controlling the size of SiC and Al particles. |
| FILED | Monday, May 09, 2005 |
| APPL NO | 11/126517 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Powder metallurgy processes 419/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364802 | Spitsberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Irene Spitsberg (Loveland, Ohio); Venkat Subramanian Venkataramani (Clifton Park, New York); Brett Allen Boutwell (Liberty Township, Ohio); Mark Daniel Gorman (West Chester, Ohio); Robert William Bruce (Loveland, Ohio) |
| ABSTRACT | Ceramic compositions comprising at least about 91 mole % zirconia and up to about 9 mole % of a stabilizer component comprising a first metal oxide having selected from the group consisting of yttria, calcia, ceria, scandia, magnesia, india and mixtures thereof. This stabilizer component further comprises a second metal oxide of a trivalent metal atom selected from the group consisting of lanthana, gadolinia, neodymia, samaria, dysprosia, erbia, ytterbia, and mixtures thereof. These ceramic compositions are useful in preparing thermal barrier coatings having reduced thermal conductivity for the metal substrate of articles that operate at, or are exposed to, high temperatures. |
| FILED | Tuesday, December 30, 2003 |
| APPL NO | 10/748520 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/633 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364807 | Boutwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Brett Allen Rohrer Boutwell (Liberty Township, Ohio); Irene Spitsberg (Loveland, Ohio); Christine Govern (Cincinnati, Ohio); Bangalore A. Nagaraj (West Chester, Ohio); Brian Thomas Hazel (West Chester, Ohio); Ramgopal Darolia (West Chester, Ohio); Curtis Alan Johnson (Niskayuna, New York); Yan Gao (Niskayuna, New York); Mark Daniel Gorman (West Chester, Ohio) |
| ABSTRACT | In accordance with an embodiment of the invention, an article is provided. The article comprises a substrate comprised of silicon containing material, an environmental barrier coating (EBC) overlying the substrate and a thermal barrier coating (TBC) on the environmental barrier coating. The thermal barrier coating comprising a compound having a rhombohedral phase. |
| FILED | Monday, December 06, 2004 |
| APPL NO | 11/006292 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/701 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364881 | Nadeau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Lloyd J. Nadeau (Callaway, Florida); Jim C. Spain (Atlanta, Georgia); Venkateswarlu Kadiyala (Anantapur, India) |
| ABSTRACT | A process for biological production of ortho-aminophenols from nitroaromatic compounds using recombinant E. Coli strains. The process uses an enzyme system that makes use of a nitroreductase enzyme that initially reduces the nitroarene to the hydroxylaminoarene and a mutase enzyme that converts the hydroxylaminoarene to an ortho-aminophenol. |
| FILED | Monday, April 11, 2005 |
| APPL NO | 11/108147 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365336 | Galica et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Gary E. Galica (Medford, Massachusetts); Francesca Scire-Scappuzzo (Somerville, Massachusetts); Joy S. G. Stafford-Evans (Andover, Massachusetts) |
| ABSTRACT | The Low-energy Imaging Particle Spectrometer (LIPS) is configured as a “pinhole camera” with particle-specific scintillator focal planes. The scintillators are designed specifically to respond only to either protons or electrons within a specific energy range. The scintillators are coupled directly to a multi-anode photomultiplier tube (PMT). Owing to their particle-specific response, the scintillators themselves provide the particle discrimination. The pulse amplitude defines the particle energy and the spatial position provides angular information. |
| FILED | Friday, May 13, 2005 |
| APPL NO | 11/129754 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365373 | Nemati et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Farid Nemati (Stanford, California); James D. Plummer (Portola Valley, California) |
| ABSTRACT | A thyristor device can be used to implement a variety of semiconductor memory circuits, including high-density memory-cell arrays and single cell circuits. In one example embodiment, the thyristor device includes doped regions of opposite polarity, and a first word line that is used to provide read and write access to the memory cell. A second word line is located adjacent to and separated by an insulative material from one of the doped regions of the thyristor device for write operations to the memory cell, for example, by enhancing the switching of the thyristor device from a high conductance state to a low conductance state and/or from the low conductance state to the high conductance. This type of memory circuit can be implemented to significantly reduce standby power consumption and access time. |
| FILED | Thursday, August 18, 2005 |
| APPL NO | 11/206627 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365398 | Tiwari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Sandip Tiwari (Ithaca, New York); Arvind Kumar (Ithaca, New York) |
| ABSTRACT | A highly dense form of static random-access memory (SRAM) takes advantage of transistor gates on both sides of silicon and high interconnectivity made possible by the complex form of silicon-on-insulator and three-dimensional integration. This technology allows one to form p-channel and n-channel devices very compactly by taking advantage of placement of gates on both sides, making common contacts and dense interconnections in 3D. |
| FILED | Friday, February 11, 2005 |
| APPL NO | 11/055014 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/368 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365650 | Ruffa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
| ABSTRACT | An underwater RF signal propagation path is created by utilizing a plurality of individual RF transceivers such as MEMS RF transceivers. Each MEMS RF transceiver has a predetermined buoyancy. A stream of the RF transceivers are released to form a line of RF transceivers underwater such that the individual RF transceivers have an RF transmission and reception distance greater than the distance between the RF transceivers whereby an RF signal can be repeatedly retransmitted down the line of RF transceivers. |
| FILED | Monday, December 19, 2005 |
| APPL NO | 11/326671 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/850 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365838 | Jones |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Michael I. Jones (Azle, Texas) |
| ABSTRACT | An apparatus measures optical deviations caused by an aircraft canopy. In this apparatus, a light source generates a beam of light. A collimator, optically coupled to the light source, then collimates the beam of light. An optical assembly patterns the collimated beam of light into a patterned array of subaperture beams, which is directed onto an imaging screen. The patterned collimated beam of light produces images, which are electronically imaged and recorded to memory. An undistorted image results when the aircraft canopy is not placed in a path of the patterned collimated beam of light. However, a distorted image results when the aircraft canopy is placed in a path of the patterned collimated beam of light and distorts the patterned collimated beam of light. A processing unit compares the distorted image to the undistorted image to determine the optical distortions caused by the aircraft canopy. |
| FILED | Friday, April 02, 2004 |
| APPL NO | 10/817538 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366009 | Katti |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Romney R. Katti (Maple Grove, Minnesota) |
| ABSTRACT | A magnetoresistive device is provided with separate read and write architecture. In one embodiment, a magnetic tunnel junction (MTJ) has a nonmagnetic nonconductive barrier layer sandwiched between two ferromagnetic conducting layers. A first read line is coupled to a first ferromagnetic layer and a second read line is coupled to a second ferromagnetic layer such that a voltage difference between the two read lines will produce a current flowing perpendicularly through each layer of the MTJ. A first write line is separated from the first read line by a first insulator and a second write line is separated from the second read line by a second insulator. |
| FILED | Saturday, January 10, 2004 |
| APPL NO | 10/754880 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366372 | Lange |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Charles H. Lange (Glendale, Arizona) |
| ABSTRACT | An optical waveguide device is provided for receiving light that has a guided mode and an unguided mode. The device comprises an optically transmissive substrate having first and second substantially opposite surfaces, an input end, and an output end. An optical waveguide region is disposed within the substrate and extends from the input to the output. A plurality of electrodes is disposed on the first surface at predetermined locations with respect to the waveguide region. The device includes a plurality of optical barriers each disposed proximate one of the first and second surfaces and positioned to block a different optical path of the unguided mode. |
| FILED | Monday, February 27, 2006 |
| APPL NO | 11/364024 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366376 | Shishkov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Milen Shishkov (Watertown, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts) |
| ABSTRACT | Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical cooperation with the optical fiber. The optical arrangement may have a first surface having a portion that is perpendicular to a second axis, and a second surface which includes a curved portion. The first axis can be provided at a particular angle that is more than 0° and less than 90° with respect to the second axis. |
| FILED | Thursday, September 29, 2005 |
| APPL NO | 11/241907 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366419 | Ngo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | Kiet D. Ngo (Hermosa Beach, California); David P. Dixon (Torrance, California); Steven B. Schrier (Hawthorne, California) |
| ABSTRACT | Apparatus, and a corresponding method, for spatially isolating a transmit beam and a receive beam, which, in satellite communication systems, are inherently separated by a look ahead angle. A receive beam separation mirror is positioned in the receive beam path but out of the transmit beam path, and the receive beam is reflected along a path separated from the transmit beam path. The mirror may be annular, allowing the transmit beam to be directed through the center of the mirror. In applications where a desired isolation angle is different from the look ahead angle, or where there is no look ahead angle, the receive beam separation mirror is used in conjunction with a dichroic beam splitter and at least one receive beam steering mirror, to achieve the desired angular separation. |
| FILED | Monday, November 22, 2004 |
| APPL NO | 10/994570 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366564 | Szu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Harold H. Szu (Bethesda, Maryland); James R. Buss (Arlington, Virginia); Ivica Kopriva (Washington, District of Columbia) |
| ABSTRACT | Changes, increase or decrease, in the body fluid flow are passively detected by using a single pixel, non-linear blind de-mixing procedure, which can be extended to general biomedical measurement and diagnoses instruments. More specifically the single pixel, non-linear blind de-mixing procedure is applied on the hot spots of rheumatic arthritis or breast cancer detection problem using passive two-color infrared imaging as well as to passively detect blockages in the body fluid circulatory system that might be of importance for coronary artery bypass surgery, diabetes and deep vein thrombosis. Other applications of the mentioned algorithm include a pair of cameras for video, a pair of antennas for cell phones, and in situ data gathering or imaging using multiple mode fiberoptical sensing as well as selective amplification hearing aids through two-ear binaural processing for de-noise echo cancellation and signal classification. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/652086 |
| ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366622 | Nemir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | X-L Synergy (El Paso, Texas) |
| INVENTOR(S) | David C. Nemir (El Paso, Texas); Jan B. Beck (El Paso, Texas) |
| ABSTRACT | An apparatus and method for the identification of arcing phenomena in a faulted electrical network. By continually updating a model for the load on an electrical branch, an estimate of the behavior of that load may be calculated. Since electrical arcing faults result in a chaotic behavior that is difficult to describe, when arcing occurs, the model will be unable to adequately describe the arcing behavior and this inability indicates a fault condition, in response to which, power may be removed in full or in part from the faulted electrical network. In some embodiments, a current shunt is used to distinguish between source side and load side arcing. Some embodiments utilize a solid state switch as both current shunt and interruption means. |
| FILED | Monday, October 17, 2005 |
| APPL NO | 11/252404 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/58 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366908 | Tewfik |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Digimarc Corporation (Beaverton, Oregon) |
| INVENTOR(S) | Ahmed Tewfik (Edina, Minnesota) |
| ABSTRACT | A digital watermark detection method exploits autocorrelation properties of the watermarked signal that enable synchronization of the digital watermark despite temporal or geometric distortion of the host signal. Other watermark methods employ keys, including a key dependent on the content in which the watermark is embedded and another key that is not dependent on the content. |
| FILED | Monday, April 30, 2001 |
| APPL NO | 10/360794 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/176 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07367020 | Bickle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Gerald L. Bickle (Columbia City, Indiana); Jimmie T. Marks (Fort Wayne, Indiana); Philip A. Eyermann (Churubusco, Indiana) |
| ABSTRACT | An executable radio software system including a core framework layer responsive to one or more applications and a middleware layer. The core framework layer includes isolated platform dependent code in one or more files for a number of different platforms each selectively compilable by a directive to reduce the dependency of the core framework layer on a specific platform. Also, the core framework layer includes an embedded distributed parser responsive to the Domain profiles of the applications for more efficiently installing and running an application. |
| FILED | Monday, July 29, 2002 |
| APPL NO | 10/207315 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07364296 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Donald T. Miller (Bloomington, Indiana); Ravi S. Jonnal (Bloomington, Indiana); Junle Qu (Bloomington, Indiana); Karen E. Thorn (Lower Hutt, New Zealand) |
| ABSTRACT | The invention provides a method of optical imaging comprising providing a sample to be imaged, measuring and correcting aberrations associated with the sample using adaptive optics, and imaging the sample by optical coherence tomography. The method can be used to image the fundus of a human eye to provide diagnostic information about retinal pathologies such as macular degeneration, retinitis pigmentosa, glaucoma, or diabetic retinopathy. The invention further provides an apparatus comprising an adaptive optics subsystem and a two-dimensional optical coherence tomography subsystem. |
| FILED | Wednesday, June 11, 2003 |
| APPL NO | 10/517367 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364675 | Guan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Jingjiao Guan (Columbus, Ohio); Derek J. Hansford (Columbus, Ohio); L. James Lee (Columbus, Ohio) |
| ABSTRACT | A method for forming three-dimensional polymeric particulate microstructures through self-folding of thin-film microparticles. Self-folding of two-dimensional polymeric precursors produces various three-dimensional particulate microstructures. Dumpling-like microstructures with oil cores and polymer coats are prepared by an interfacial-tension driven self-folding method. Roll-like and bowl-shaped hydrogel microstructures are fabricated by self-folding induced by differential volume shrinkage. Curled microstructures are produced by self-folding that is the result of a two-polymer or bilayer method wherein one of the polymers is a volume changeable polymer. |
| FILED | Tuesday, November 04, 2003 |
| APPL NO | 10/700715 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364882 | Iwata-Reuyl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Portland State University (Portland, Oregon); Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Dirk Iwata-Reuyl (Corbett, Oregon); Valérie de Crecy-Lagard (Gainesville, Florida); Steven G. Van Lanen (Madison, Wisconsin) |
| ABSTRACT | A new class of enzymes that catalyze the conversion of a nitrile containing compound to the corresponding amine (such as a primary amine) are disclosed. Such enzymes are referred to herein as nitrile oxido-reductases. Methods of using the enzymes to reduce a nitrile to a amine, for example in vitro or in vivo, are provided. Such methods provide the first biocatalysis method for reducing nitrites to amines, and provides an alternative to currently used methods, which generally utilize harsh reaction conditions and the production of hazardous waste. While the hydrolysis of nitrites to amides and carboxylic acids via biocatalysis has found extensive use in industry, the lack of a known nitrile oxido-reductase has precluded the application of biocatalysis to nitrile reduction. |
| FILED | Monday, September 26, 2005 |
| APPL NO | 11/235933 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365234 | Subramaniam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Bala Subramaniam (Lawrence, Kansas); Jon A. Tunge (Lawrence, Kansas); Hong Jin (Bartlesville, Oklahoma); Anindya Ghosh (Duncan, Oklahoma) |
| ABSTRACT | An improved hydroformylation process is provided, which comprises reacting an olefin with CO and H2 in the presence of a hydroformylation catalyst in a liquid that has been volumetrically expanded with a compressed gas, such as supercritical carbon dioxide. |
| FILED | Friday, March 16, 2007 |
| APPL NO | 11/687270 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/451 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365699 | Grebel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Haim Grebel (Livingston, New Jersey); Nan Ni (Beijing, China PRC) |
| ABSTRACT | A dipole array is provided for use as an Ultra Short Pulse (USP) transmitter or receiver in UWB communications systems, which reduces the output pulse dispersion. Instead of having all the dipole elements serially fed by a transmission line, the feeding in the array is made independently through a central point and the radiation is emitted and received broadsided with respect to the array plane. This configuration minimizes the relative time delay between radiating resonance frequencies. |
| FILED | Tuesday, May 17, 2005 |
| APPL NO | 11/130839 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/810 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365744 | Fang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Hui Fang (Champaign, Illinois); John C. Hart (Champaign, Illinois) |
| ABSTRACT | A method of the invention includes the steps of selecting at least a portion of an image on which to superimpose a texture and segmenting that portion of the image into a plurality of clusters. Each of the clusters is then parameterized with texture coordinates, and texture is assigned to each of the clusters using the texture coordinates to result in a texture patch. The texture patches are then blended together. This exemplary method of the invention has the result of the texture patches appearing to adopt the surface undulations of the underlying surface. |
| FILED | Monday, July 26, 2004 |
| APPL NO | 10/899268 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366645 | Ben-Arie |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Jezekiel Ben-Arie (Chicago, Illinois) |
| INVENTOR(S) | Jezekiel Ben-Arie (Chicago, Illinois) |
| ABSTRACT | A method for recognition of an input human motion as being the most similar to one model human motion out of a collection of stored model human motions. In the preferred method, both the input and the model human motions are represented by vector sequences that are derived from samples of angular poses of body parts. The input and model motions are sampled at substantially different rates. A special optimization algorithm that employs sequencing constraints and dynamic programming, is used for finding the optimal input-model matching scores. When only partial body pose information is available, candidate matching vector pairs for the optimization are found by indexing into a set of hash tables, where each table pertains to a sub-set of body parts. The invention also includes methods for recognition of vector sequences and for speech recognition. |
| FILED | Thursday, May 01, 2003 |
| APPL NO | 10/427882 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366711 | McKeown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the city of New York (New York, New York) |
| INVENTOR(S) | Kathleen R. McKeown (Wayne, New Jersey); Regina Barzilay (New York, New York) |
| ABSTRACT | A summary for a collection of related documents can be generated by extracting phrases from the documents which include common focus elements. Phrase intersection analysis is then performed on the extracted phrases to generate a phrase intersection table, where identical or equivalent phrases are identified. Temporal processing on the phrases in the phrase intersection table is performed to remove ambiguous time references and to sort the phrases in a temporal sequence. Sentence generation is then used to combine the phrases in the phrase intersection table into a coherent summary. |
| FILED | Friday, February 18, 2000 |
| APPL NO | 09/913745 |
| ART UNIT | 2162 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07366908 | Tewfik |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Digimarc Corporation (Beaverton, Oregon) |
| INVENTOR(S) | Ahmed Tewfik (Edina, Minnesota) |
| ABSTRACT | A digital watermark detection method exploits autocorrelation properties of the watermarked signal that enable synchronization of the digital watermark despite temporal or geometric distortion of the host signal. Other watermark methods employ keys, including a key dependent on the content in which the watermark is embedded and another key that is not dependent on the content. |
| FILED | Monday, April 30, 2001 |
| APPL NO | 10/360794 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/176 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07367024 | Barua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland (Riverdale, Maryland) |
| INVENTOR(S) | Rajeev Kumar Barua (Rockville, Maryland); Sumesh Udayakumaran (Hyattsville, Maryland) |
| ABSTRACT | A highly predictable, low overhead and yet dynamic, memory allocation methodology for embedded systems with scratch-pad memory is presented. The dynamic memory allocation methodology for global and stack data (i) accounts for changing program requirements at runtime; (ii) has no software-caching tags; (iii) requires no run-time checks; (iv) has extremely low overheads; and (v) yields 100% predictable memory access times. The methodology provides that for data that is about to be accessed frequently is copied into the SRAM using compiler-inserted code at fixed and infrequent points in the program. Earlier data is evicted if necessary. |
| FILED | Tuesday, September 21, 2004 |
| APPL NO | 10/945651 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07364890 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Midwest Research Institute (Kansas City, Missouri) |
| INVENTOR(S) | Shi-You Ding (Golden, Colorado); William S. Adney (Golden, Colorado); Todd B. Vinzant (Golden, Colorado); Michael E. Himmel (Littleton, Colorado) |
| ABSTRACT | The invention provides a thermal tolerant (thermostable) cellulase, AviIII, that is a member of the glycoside hydrolase (GH) family. AviIII was isolated and characterized from Acidothermus cellulolyticus and, like many cellulases, the disclosed polypeptide and/or its derivatives may be useful for the conversion of biomass into biofuels and chemicals. |
| FILED | Saturday, July 28, 2001 |
| APPL NO | 09/917376 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365102 | Weissman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | Jeffrey G. Weissman (West Henrietta, New York) |
| ABSTRACT | In a process for forming a methane-enriched fuel, a hydrocarbon feedstock that includes hydrocarbons having molecular weights greater than that of methane (CH4) is mixed with an oxidizable gaseous reactant that includes water (H2O) and is free of molecular oxygen (O2). The mixture, which has a H2O/total hydrocarbon (H2O/C) ratio of less than about 1, is heated to an elevated temperature in the presence of a catalyst to form a methane-enriched pre-reformate product. At least a portion of the feedstock hydrocarbons having molecular weights greater than that of methane is converted to methane (CH4) in the process. |
| FILED | Monday, February 26, 2007 |
| APPL NO | 11/710820 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Chemistry: Fischer-Tropsch processes; or purification or recovery of products thereof 518/700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365118 | McCleskey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Thomas M. McCleskey (Los Alamos, New Mexico); Anthony K. Burrell (Los Alamos, New Mexico); Quanxi Jia (Los Alamos, New Mexico); Yuan Lin (Los Alamos, New Mexico) |
| ABSTRACT | A polymer assisted deposition process for deposition of metal oxide films is presented. The process includes solutions of one or more metal precursor and soluble polymers having binding properties for the one or more metal precursor. After a coating operation, the resultant coating is heated at high temperatures to yield metal oxide films. Such films can be epitaxial in structure and can be of optical quality. The process can be organic solvent-free. |
| FILED | Tuesday, July 08, 2003 |
| APPL NO | 10/616479 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 524/401 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365121 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Jianhua Huang (Blacksburg, Virginia); Donald G. Baird (Blacksburg, Virginia); James E. McGrath (Blacksburg, Virginia) |
| ABSTRACT | A low cost method of fabricating bipolar plates for use in fuel cells utilizes a wet lay process for combining graphite particles, thermoplastic fibers, and reinforcing fibers to produce a plurality of formable sheets. The formable sheets are then molded into a bipolar plates with features impressed therein via the molding process. The bipolar plates formed by the process have conductivity in excess of 150 S/cm and have sufficient mechanical strength to be used in fuel cells. The bipolar plates can be formed as a skin/core laminate where a second polymer material is used on the skin surface which provides for enhanced conductivity, chemical resistance, and resistance to gas permeation. |
| FILED | Wednesday, February 18, 2004 |
| APPL NO | 10/779804 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 524/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365312 | Laskin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Julia Laskin (Richland, Washington); Jean H. Futrell (Richland, Washington) |
| ABSTRACT | The invention relates to a method and apparatus for enhanced sequencing of complex molecules using surface-induced dissociation (SID) in conjunction with mass spectrometric analysis. Results demonstrate formation of a wide distribution of structure-specific fragments having wide sequence coverage useful for sequencing and identifying the complex molecules. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 11/605881 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365330 | Sun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jiangang Sun (Westmont, Illinois) |
| ABSTRACT | A computer-implemented method for automated thermal computed tomography includes providing an input of heat, for example, with a flash lamp, onto the surface of a sample. The amount of heat and the temperature rise necessary are dependent on the thermal conductivity and the thickness of the sample being inspected. An infrared camera takes a rapid series of thermal images of the surface of the article, at a selected rate, which can vary from 100 to 2000 frames per second. Each infrared frame tracks the thermal energy as it passes from the surface through the material. Once the infrared data is collected, a data acquisition and control computer processes the collected infrared data to form a three-dimensional (3D) thermal effusivity image. |
| FILED | Monday, September 18, 2006 |
| APPL NO | 11/522757 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365672 | Keller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Paul E. Keller (Richland, Washington); Thomas E. Hall (Kennewick, Washington); Douglas L. McMakin (Richland, Washington) |
| ABSTRACT | Disclosed are systems, methods, devices, and apparatus to determine if a clothed individual is carrying a suspicious, concealed object. This determination includes establishing data corresponding to an image of the individual through interrogation with electromagnetic radiation in the 200 MHz to 1 THz range. In one form, image data corresponding to intensity of reflected radiation and differential depth of the reflecting surface is received and processed to detect the suspicious, concealed object. |
| FILED | Thursday, October 30, 2003 |
| APPL NO | 10/697965 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365835 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sheng Wu (San Gabriel, California); Yongchun Tang (Walnut, California) |
| ABSTRACT | To further isolate the scattered light 112 of a specific particle from the scattered light of a different particle, a pin hole device 116 can be used. The pin hole device 116 prevents unfocused light from other particles from entering the second plane 118, thus isolating a desired, focused image of one particle 110 of the sample 106. In one embodiment, the pin hole 116 has a size of several microns. At the second plane 118, a traditional imaging detection device 120 detects the defocused light. The position of the second image plane 118 is chosen for good angular resolution of the scattered light 112, and at the same time gives enough light for the imaging detection device 120 to obtain a sufficient reading. |
| FILED | Thursday, December 02, 2004 |
| APPL NO | 11/004492 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/237.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07364745 | Bandara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Aloka B. Bandara (Blacksburg, Virginia); Stephen M. Boyle (Blacksburg, Virginia); Nammalwar Sriranganathan (Blacksburg, Virginia); Gerhardt G. Schurig (Blacksburg, Virginia) |
| ABSTRACT | A recombinant, attenuated strain of Brucella suis or Brucella melitensis with a deficiency in carboxyl-terminal protease activity or tail-specific protease activity can be used as a vaccine for the prevention or treatment of Brucellosis. Prior exposure to the Brucella species is identified by detecting a genetic sequence for carboxyl-terminal (i.e. tail-specific) protease activity in a biological sample. |
| FILED | Tuesday, October 11, 2005 |
| APPL NO | 11/246957 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07364763 | Hultin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Herbert O. Hultin (Rockport, Massachusetts); Halldor Sigfusson (Stillwater, Oklahoma); Marbelly A. Davila Cordido (Caracas, Venezuela) |
| ABSTRACT | The invention relates to methods of reducing oxidation in foods by selectively adding one or more antioxidants to the polar lipid fraction of a food product. |
| FILED | Wednesday, November 01, 2000 |
| APPL NO | 10/111939 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Food or edible material: Processes, compositions, and products 426/541 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365182 | Van Nocker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Michigan State University (Lansing, Michigan) |
| INVENTOR(S) | Steven R. Van Nocker (East Lansing, Michigan); Hua Zhang (Holt, Michigan) |
| ABSTRACT | The present invention relates to plant genes involved in regulating flowering, and especially to genes involved in the induction of flowering in response to cold, or vernalization. In particular, the present invention provides the identification, cloning, and characterization of genes involved in vernalization, and specifically of VIP genes, as well as to the proteins encoded by these genes, and to methods of using the VIP genes and proteins. Mutants of VIP genes, where the mutation is a knock-out mutation, confer a vernalization independence, or constitutively vernalized, phenotype in a plant which in the non-mutant form requires vernalization to flower. |
| FILED | Thursday, May 01, 2003 |
| APPL NO | 10/427224 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07364079 | Raney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Brent A. Raney (Sterling, Virginia); Daryl S. Hamilton (Hyattsville, Maryland); Anthony M. Ferlaino, Jr. (Fairfax, Virginia) |
| ABSTRACT | An improved tracking label may comprise a destination ZIP field (130), content identifier number (CIN) description field (115), and a barcode field (150). In addition, the improved label comprises at least one of a printer line field (105), a postal destination name field (110),a mailer name field (120), a mailer identification (ID) field (125), a route field (135), a barcode numermic line field (140) and a mailer's area field (145). |
| FILED | Thursday, February 21, 2002 |
| APPL NO | 10/468297 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Registers 235/462.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07367058 | Lawson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Alfred D. Lawson (Washington, District of Columbia) |
| ABSTRACT | A method is described that provides efficient, secure web-based recognition services. More particularly, an embodiment of the method relates to confidential encoding by dissociating image information into individual word segments, or snippets, at a distribution point and distributing the snippets over a network to users who subscribe to provide their services. Users could include college students, housewives, or any individual with Internet access. The users view the snippets, enter equivalent ASCII information for the snippets, and send the ASCII information back over the network to the distribution point for reassembly. |
| FILED | Tuesday, May 28, 2002 |
| APPL NO | 10/158036 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Information security 726/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07366361 | Cheng |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sarnoff Corporation (Princeton, New Jersey) |
| INVENTOR(S) | Hui Cheng (Bridgewater, New Jersey) |
| ABSTRACT | A processed (e.g., captured) video sequence is temporally, spatially, and/or histogram registered to the corresponding original video sequence by generating, for each set of one or more processed frames, a mapping from a selected set of one or more original frames to the processed set, wherein (1) each selected set depends on the selected set corresponding to a previous processed set, (2) each mapping minimizes a local prediction error between the original set and the corresponding processed set, and (3) the accumulated prediction error for the entire processed video sequence is minimized. |
| FILED | Wednesday, March 03, 2004 |
| APPL NO | 10/792073 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/294 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07364853 | Bacher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Promega Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Jeffery W. Bacher (Madison, Wisconsin); Laura Flanagan (Fort Atkinson, Wisconsin); Nadine Nassif (Madison, Wisconsin) |
| ABSTRACT | Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits of the present invention can be used to detect or diagnose diseases associated with microsatellite instability, such as certain types of cancer. |
| FILED | Tuesday, January 18, 2005 |
| APPL NO | 11/037321 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07364882 | Iwata-Reuyl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Portland State University (Portland, Oregon); Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Dirk Iwata-Reuyl (Corbett, Oregon); Valérie de Crecy-Lagard (Gainesville, Florida); Steven G. Van Lanen (Madison, Wisconsin) |
| ABSTRACT | A new class of enzymes that catalyze the conversion of a nitrile containing compound to the corresponding amine (such as a primary amine) are disclosed. Such enzymes are referred to herein as nitrile oxido-reductases. Methods of using the enzymes to reduce a nitrile to a amine, for example in vitro or in vivo, are provided. Such methods provide the first biocatalysis method for reducing nitrites to amines, and provides an alternative to currently used methods, which generally utilize harsh reaction conditions and the production of hazardous waste. While the hydrolysis of nitrites to amides and carboxylic acids via biocatalysis has found extensive use in industry, the lack of a known nitrile oxido-reductase has precluded the application of biocatalysis to nitrile reduction. |
| FILED | Monday, September 26, 2005 |
| APPL NO | 11/235933 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07364904 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | PXE International, Inc. (Washington, District of Columbia); The University of Hawaii (Honolulu, Hawaii) |
| INVENTOR(S) | Charles D. Boyd (Honolulu, Hawaii); Katalin Csiszar (Honolulu, Hawaii); Olivier LeSaux (Honolulu, Hawaii); Zsolt Urban (Honolulu, Hawaii); Sharon Terry (Potomac, Maryland) |
| ABSTRACT | Methods and compositions are provided for diagnosing and treating Pseudoxanthoma elasticum (PXE) patients and PXE carriers. Methods and compositions are based on the discovery that PXE mutations are located in the MRP6 (ABCC6) gene. |
| FILED | Friday, January 23, 2004 |
| APPL NO | 10/764328 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365533 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Seong-Jae Lee (Ames, Iowa); Sang-Hoon Song (Ames, Iowa); Yevgen Melikhov (Penarth, United Kingdom); Choon-Mahn Park (Seoul, South Korea); Hans Hauser (Vienna, Austria); David Jiles (Glamorgan, United Kingdom) |
| ABSTRACT | A system and method to detect angular rotation, linear displacement and/or surface deformations is presented. The method is based on the ability of a linear polarized light to interact with magnetic materials and to change its polarization angle due to Faraday effect. A basic structure of the system consists of a magneto-optic (MO) film with a two-domain structure and a single domain wall which are generated by gradient magnetic field produced by opposite polarity permanent magnets placed near the film. An AC magnetic field applied perpendicular to the MO film surface causes the magnetic domain wall in the MO film to oscillate at the same frequency. This leads to a detected output AC modulated signal. By measuring the temporal changes in this signal, information on angular rotation, linear displacement and/or surface deformation can be obtained. |
| FILED | Friday, July 21, 2006 |
| APPL NO | 11/459157 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/244.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07365858 | Fang-Yen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher M. Fang-Yen (Somerville, Massachusetts); Gabriel Popescu (Brighton, Massachusetts); Changhuei Yang (Pasadena, California); Adam Wax (Chapel Hill, North Carolina); Ramachandra R. Dasari (Lexington, Massachusetts); Michael S. Feld (Newton, Massachusetts) |
| ABSTRACT | Preferred embodiments of the present invention are directed to systems for phase measurement which address the problem of phase noise using combinations of a number of strategies including, but not limited to, common-path interferometry, phase referencing, active stabilization and differential measurement. Embodiment are directed to optical devices for imaging small biological objects with light. These embodiments can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. The structure and dynamics of sub-cellular constituents cannot be currently studied in their native state using the existing methods and technologies including, for example, x-ray and neutron scattering. In contrast, light based techniques with nanometer resolution enable the cellular machinery to be studied in its native state. Thus, preferred embodiments of the present invention include systems based on principles of interferometry and/or phase measurements and are used to study cellular physiology. These systems include principles of low coherence interferometry (LCI) using optical interferometers to measure phase, or light scattering spectroscopy (LSS) wherein interference within the cellular components themselves is used, or in the alternative the principles of LCI and LSS can be combined to result in systems of the present invention. |
| FILED | Tuesday, April 13, 2004 |
| APPL NO | 10/823389 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 29, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
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THE PANEL
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FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
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APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080429.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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