FedInvent™ Patents
Patent Details for Tuesday, May 13, 2008
This page was updated on Monday, March 27, 2023 at 12:57 AM GMT
Department of Defense (DOD)
| US 07370537 | O'Brien et al. |
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| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Michael J. O'Brien (Los Angeles, California); Benjamin A. Nelson (Los Angeles, California); Michael R. Hilton (Westminster, California) |
| ABSTRACT | An acoustical mechanical test method prescribes compressing brittle balls in spherical conforming opposing platens producing equatorial bulging, tensile stresses, and resulting in crack or flaw growth with emissions of acoustical sounds for direct identification of brittle balls having a flaw exceeding a maximum allowable size, such as flaws in silicon-nitride balls used in hybrid bearings as well as conventional steel ball bearings. |
| FILED | Monday, November 15, 2004 |
| APPL NO | 10/989180 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/818 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07370903 | Barbee et al. |
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| ASSIGNEE(S) | United Protective Technologies, LLC (Charlotte, North Carolina) |
| INVENTOR(S) | Brent W. Barbee (Stanfield, North Carolina); E. Andrew Hough (Charlotte, North Carolina) |
| ABSTRACT | A transparent laminated structure having multiple peel-away laminated film layers for protecting windscreens, particularly windscreens of rotary aircraft, from environmental conditions. The laminated structure includes at least one laminated layer wherein each layer includes a film, a bonding layer on a first major side of the film for releaseably attaching the film to either the windscreen or to an adjacent laminated film layer, a conductive material on a second major side of the film for dissipating electrostatic charging in the laminated structure that may occur due to accumulated precipitation static during aircraft fight, and a hard coat layer for protecting the relatively softer film against abrasion. As the outermost film layer becomes degraded below acceptable levels, that film may be easily removed, exposing a subsequent unblemished film layer. |
| FILED | Friday, July 30, 2004 |
| APPL NO | 10/909129 |
| ART UNIT | 3612 — Fluid Handling and Dispensing |
| CURRENT CPC | Land vehicles: Bodies and tops 296/95.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371051 | Bau |
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| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Haim H. Bau (Swarthmore, Pennsylvania) |
| ABSTRACT | The present invention relates to controlled, magnetohydrodynamically-driven, fluidic networks containing a plurality of individually controlled branches. The branches consist of conduits equipped with pairs of electrodes that are controlled by electrode controllers. In operation, the network is placed within a magnetic field and potentials or currents are applied across electrode pairs within the various branches of the network in specifically determined magnitudes and polarities for specifically determined time intervals in accordance with an activation sequence that may be determined by an algorithm. Placed within a temperature gradient, at least a part of the network can act as a thermal cycler for use in biological interactions that employ temperature variations. The invention also relates to magnetohydrodynamic stirrers comprising a conduit or cavity having at least two electrodes disposed in such an orientation that, upon the application of a potential or current across the electrode pair within a magnetic field, secondary flows such as chaotic advection is generated. |
| FILED | Monday, September 08, 2003 |
| APPL NO | 10/657302 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Pumps 417/50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371216 | Weyand et al. |
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| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Peter G. Weyand (Houston, Texas); Matthew W. Bundle (Houston, Texas) |
| ABSTRACT | The present invention includes a method for assessing the fitness of an individual. In one embodiment, the method comprises providing a physical fitness value of an individual by measuring a first trial of an activity conducted by the individual to provide a first measured component. The method further comprises measuring a second trial of an activity conducted by the individual to provide a second measured component. In addition, the method comprises determining the physical fitness values from the first and second measured components. In some embodiments, the method comprises estimating speed or mechanical power output values for the individual over a desired duration. In other embodiments, the method comprises determining the VO2 max of the individual. |
| FILED | Thursday, January 06, 2005 |
| APPL NO | 11/030674 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371400 | Borenstein et al. |
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| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeffrey T. Borenstein (Cambridge, Massachusetts); Kevin R. King (Cambridge, Massachusetts); Hidetomi Terai (Osaka, Japan); Joseph P. Vacanti (Boston, Massachusetts) |
| ABSTRACT | The invention provides for translating two-dimensional microfabrication technology into the third dimension. Two-dimensional templates are fabricated using high-resolution molding processes. These templates are then bonded to form three-dimensional scaffold structures with closed lumens. The scaffolds can serve as the template for cell adhesion and growth by cells that are added to the scaffolds through the vessels, holes or pores. These scaffolds can be formed by layering techniques, to interconnect flat template sheets to build up a fully vascularized organ. |
| FILED | Wednesday, January 02, 2002 |
| APPL NO | 10/038891 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371457 | Oldenburg et al. |
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| ASSIGNEE(S) | William Marsh Rich University (Houston, Texas) |
| INVENTOR(S) | Steven J. Oldenburg (Houston, Texas); Richard D. Averitt (Houston, Texas); Nancy J. Halas (Houston, Texas) |
| ABSTRACT | The present invention is for particulate compositions and methods for producing them that can absorb or scatter electromagnetic radiation. The particles are homogeneous in size and are comprised of a nonconducting inner layer that is surrounded by an electrically conducting material. The ratio of the thickness of the nonconducting layer to the thickness of the outer conducting shell is determinative of the wavelength of maximum absorbance or scattering of the particle. Unique solution phase methods for synthesizing the particles involve linking clusters of the conducting atoms, ions, or molecules to the nonconducting inner layer by linear molecules. This step can be followed by growth of the metal onto the clusters to form a coherent conducting shell that encapsulates the core. |
| FILED | Tuesday, January 06, 2004 |
| APPL NO | 10/752181 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371538 | Simpson et al. |
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| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Michael L. Simpson (Knoxville, Tennessee); Michael J. Paulus (Knoxville, Tennessee); Gary S. Sayler (Blaine, Tennessee); Bruce M. Applegate (West Lafayette, Indiana); Steven A. Ripp (Knoxville, Tennessee) |
| ABSTRACT | An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on the chip for processing the photocurrent. A distributed electrode configuration including a plurality of spaced apart electrodes disposed on an active region of the photodetector is preferably used to raise efficiency. |
| FILED | Tuesday, June 14, 2005 |
| APPL NO | 11/151964 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371714 | Johnston et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | David S. Johnston (Gunpowder, Maryland); Gennady E. Platoff (Millersville, Maryland); Steven I. Baskin (Bel Air, Maryland); Thomas P. Logan (Bel Air, Maryland) |
| ABSTRACT | A composition and methods of use for the decontamination of chemical agents, including chemical warfare agents. The decontamination composition is nontoxic, nonflammable and non-corrosive and includes an effective amount of a perfluorinated alkyl bromide or reactive perfluorinated alkyl bromide. The decontamination composition may include an oxidizer and a solvent. |
| FILED | Thursday, June 22, 2006 |
| APPL NO | 11/472434 |
| ART UNIT | 1796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Cleaning compositions for solid surfaces, auxiliary compositions therefor, or processes of preparing the compositions 510/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371719 | Stupp et al. |
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| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Jeffrey D. Hartgerink (Pearland, Texas); Elia Beniash (Auburndale, Massachusetts) |
| ABSTRACT | Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/368517 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371784 | Guillot et al. |
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| ASSIGNEE(S) | Alliant Techsystems Inc. (Edina, Minnesota) |
| INVENTOR(S) | David G. Guillot (Tremonton, Utah); Albert R. Harvey (Brigham City, Utah) |
| ABSTRACT | A novel and improved EPDM formulation for a solid propellant rocket motor is described wherein hexadiene EPDM monomer components are replaced by alkylidene norbornene components, and, with appropriate adjustment of curing and other additives, functionally required rheological and physical characteristics are achieved with the desired compatibility with any one of a plurality of solid filler materials, e.g., powder silica, carbon fibers or aramid fibers, and with appropriate adhesion and extended storage or shelf-life characteristics. |
| FILED | Tuesday, August 31, 2004 |
| APPL NO | 10/931778 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 523/138 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371809 | Brandt et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
| ABSTRACT | This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and nonenveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections. |
| FILED | Tuesday, February 06, 2001 |
| APPL NO | 09/777560 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371821 | Ching et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wei-Mei Ching (Bethesda, Maryland); Chien-Chung Chao (North Bethesda, Maryland) |
| ABSTRACT | The inventive subject matter relates to a recombinant 110 kDa protein from O. tsutsugamuchi, Karp, Kato and Gilliam strains and for a DNA expression system containing DNA encoding the 110 kDa protein of O. tsutsugamuchi. The invention also relates to the use of these recombinant contructs in a formulation for the induction of a protective immune response against O. tsutsugamuchi invection using. The inventive subject matter also relates to a recombinant 110 kDa O. tsutsugamuchi protein or 110 kDa fragments for the production of antigen for use in immunodiagnosistic asssays for scrub typhus. |
| FILED | Tuesday, April 19, 2005 |
| APPL NO | 11/108867 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371840 | Press et al. |
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| ASSIGNEE(S) | The University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Michael F. Press (Redondo Beach, California); Bahman Saffari (Yorba Linda, California) |
| ABSTRACT | This invention provides an isolated polynucleotide encoding an ECA1 polypeptide. Also provided is the isolated ECA1 polypeptide Further provided is an antibody that specifically recognizes and binds the ECA1 polypeptide or an epitope thereof. The polynucleotides, antibodies and/or polypeptides of this invention may be components of compositions, host cells and/or gene delivery vehicles, where appropriate. In one aspect, the host cell will produce recombinant ECA1, which is further defined herein. In another aspect, the host cell is an antigen presenting cell such as a dendritic cell, and it will display an antigenic portion of the ECA1 polypeptide on its surface. The polypeptides, proteins and compositions of this invention are useful to aid in the diagnosis of a neoplastic condition of a cell of endometrioid origin. In one aspect, the method comprises detecting the presence of an overexpressed ECA1 proto-oncogene in a sample suspected of containing said cell, wherein said overexpression is indicative of the neoplastic condition of said cell. These neoplastic cells include, but are not limited to ovarian and colon carcinoma cells. |
| FILED | Wednesday, January 08, 2003 |
| APPL NO | 10/339738 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371982 | Greywall |
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| ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Dennis S. Greywall (Whitehouse Station, New Jersey) |
| ABSTRACT | A device, a Micro-Electrical-Mechanical-Switch (MEMS) safety and arming (S&A) device and a method of manufacturing the MEMS S&A. In one embodiment, the device includes a body and a MEMS shuttle movably coupled to the body. In this embodiment, the shuttle is configured to close a switch in response to being accelerated in two directions that are substantially orthogonal. |
| FILED | Friday, July 29, 2005 |
| APPL NO | 11/193870 |
| ART UNIT | 2832 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electricity: Circuit makers and breakers 2/61.45R |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372009 | Losee et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jon R. Losee (San Diego, California); J. Charles Hicks (San Diego, California); Everett W. Jacobs (San Diego, California); Wayne C. McGinnis (San Diego, California); Roger D. Boss (San Diego, California) |
| ABSTRACT | A solid-state thermal neutron detector comprises: a layered structure that includes; an electrically insulating substrate; a first electrode affixed to the substrate; a neutron-reactive layer affixed to and in ohmic contact with the first electrode; and a second electrode affixed to and in ohmic contact with the neutron-reactive layer; a voltage source electrically coupled to the first and second electrodes; and an electrical current detector electrically coupled in series between the layered structure and the voltage source. |
| FILED | Wednesday, December 18, 2002 |
| APPL NO | 10/322813 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372013 | Baehr-Jones et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Tom Baehr-Jones (Pasadena, California); Michael J. Hochberg (Pasadena, California); Axel Scherer (Laguna Beach, California) |
| ABSTRACT | A near-field scanning microscopy probe and a method for doing the same. A metal plasmon or dielectric waveguide is connected to a deformable material and coupled to a dielectric waveguide on a chip. The probe pops up out of the plane of the chip. The probe can be easily integrated with standard on-chip optical components. |
| FILED | Tuesday, April 26, 2005 |
| APPL NO | 11/116111 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372021 | Cotter et al. |
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| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Robert James Cotter (Baltimore, Maryland); Benjamin D. Gardner (Owings Mills, Maryland); John F Holland (Haslett, Michigan) |
| ABSTRACT | A time-of-flight mass spectrometer which has an iron source, an evacuated tube proximate the ion source and adapted to receive ions from the ion source, and a detector disposed at an end of the evacuated tube opposite an end proximate the ion source. The ion source is constructed to generate an electric field that changes non-linearly as a function of position along a path from the ion source to the detector. The ion source is constructed to generate an electric field that changes as a function of time, the electric field being provided to accelerate ions from the ion source to the detector. |
| FILED | Monday, February 13, 2006 |
| APPL NO | 11/352301 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372084 | Rajavel et al. |
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| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Rajesh D. Rajavel (Oak Park, California); Kenneth Elliott (Thousand Oaks, California); David H. Chow (Newbury Park, California) |
| ABSTRACT | Low power double heterojunction bipolar transistors with low parasitics, and methods for making the same is presented. A transistor is fabricated such that the collector region underneath a base contact area is deactivated. This results in a drastic reduction of the base-collector parasitic capacitance, Cbc. An embodiment of the present invention provides a transistor architecture for which the base contact area can be decoupled from the collector and hence allows for dramatic reduction in the parasitics of transistors. |
| FILED | Tuesday, December 20, 2005 |
| APPL NO | 11/313881 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/198 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372202 | Eden et al. |
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| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | J. Gary Eden (Mahomet, Illinois); Ju Gao (Champaign, Illinois); Sung-o Kim (Champaign, Illinois) |
| ABSTRACT | The invention is directed to a method and apparatus for phase-locking microdischarge device arrays and an ac, rf, or pulse-excited microdischarge. The invention provides output from a non-laser optical source that is a phase-locked array of microdischarges formed of microdischarge cavities containing discharge filler and excitation electrodes. In exemplary embodiments, entire arrays of microdischarge device optical emitters that are not lasers can be fabricated into a surface area having a largest dimension smaller than the coherence length of at least one of the emissions produced by the individual elements. In other embodiments, arrays of microdischarge devices configured in a Fresnel pattern constitute a lens suitable for both producing and focusing light. |
| FILED | Thursday, April 22, 2004 |
| APPL NO | 10/829666 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/582 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372480 | Lavrentovich et al. |
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| ASSIGNEE(S) | Kent State University (Kent, Ohio) |
| INVENTOR(S) | Oleg D. Lavrentovich (Kent, Ohio); Dmitry Voloschenko (Schaumburg, Illinois); Sergij Shiyanovskii (Kent, Ohio) |
| ABSTRACT | A liquid crystal device comprises a first and second cell wall structure; at least one liquid crystal material disposed within a space between the first and second cell wall structures; and polymer micro-structures, wherein the micro-structures are formed by polymerizing a prepolymer, and wherein said micro-structures have a shape and spatial location determined by said liquid crystal material. Permanent polymer micro-structures are formed from a liquid crystal with a non-uniform spatially modulated director field. The polymer structures have the shape and spatial location dictated by the non-uniform director field of the liquid crystal. The micro-structures are a backbone that restores the liquid crystal director field that existed during the polymerization process even when other factors, such as electric field, temperature, or surface anchoring, do not favor this restoration. The polymer micro-structures can be used in optical devices, such as diffraction gratings and deflecting and beam steering devices, and in micro-mechanical and micro-fluidic devices. |
| FILED | Tuesday, December 07, 2004 |
| APPL NO | 11/005779 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Television 348/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372551 | Delfvett et al. |
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| ASSIGNEE(S) | University of Central Florida Research Foundation (Orlando, Florida) |
| INVENTOR(S) | Peter J. Delfvett (Orlando, Florida); Kyungbum Kim (Orlando, Florida); Leonard Kisimbi (Orlando, Florida); Shinwook Lee (Orlando, Florida) |
| ABSTRACT | Provided are systems and methods for long-range, high-resolution, laser radar range detection. In one embodiment such a system includes an optical pulse modifier configured generated a stretched optical pulse and an optical amplifier configured to increase an optical power of the stretched optical pulse The system can further include an optical spectrum analyzer configured to determine a wavelength of a spectral peak that results from interference between a first amplified stretched pulse that is reflected from a target and a second amplified stretched pulse that is spectrally reversed. |
| FILED | Tuesday, July 25, 2006 |
| APPL NO | 11/492744 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optics: Measuring and testing 356/5.150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372723 | Lu et al. |
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| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Yong Lu (Rosemount, Minnesota); Romney R. Katti (Maple Grove, Minnesota) |
| ABSTRACT | The semiconductor industry seeks to reduce the risk of traditional volatile storage devices with improved non-volatile storage devices. The increased demand for a significantly advanced, efficient, and non-volatile data retention technique has driven the development of integrated giant-magneto-resistive (GMR) structures. In an embodiment, a save-on-power-down circuit that may be integrated with conventional semiconductor-based computing, logic, and memory devices to retain volatile logic states and/or volatile digital information in a non-volatile manner is provided. |
| FILED | Friday, August 11, 2006 |
| APPL NO | 11/464049 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373037 | Wu |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ming-Chiang Wu (Moraga, California) |
| ABSTRACT | A system and method of optically routing wavelength channels from within a plurality of optical inputs to any of a plurality of optical outputs. An optical wavelength-selective cross connect (WSXC) switch is described with a first stage of wavelength division multiplexing (WDM) routers which support an optical input and a plurality of optical outputs, which are interconnected to a second stage of WDM routers having a plurality of optical inputs and an optical output. The wavelength channel is routed in two stages from one of the input stage routers to an output stage router for output. It should be appreciated that the WSXC switch of the invention can be utilized for passing optical signals in either direction. In a preferred implementation integrated circuit router chips are stacked into cubes to form the routers stages which are cross coupled using a twisted butt joint to form a WSXC switch. |
| FILED | Thursday, August 31, 2006 |
| APPL NO | 11/514674 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373058 | Hochberg et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Michael J. Hochberg (Pasadena, California); Tom Baehr-Jones (Pasadena, California) |
| ABSTRACT | Methods and devices for low power optical detection and modulation in a slotted waveguide geometry filled with nonlinear electro-optic polymers are shown. Direct conversion of optical energy to electrical energy is enabled without external bias, via optical rectification, also enhancing electro-optic modulation. |
| FILED | Friday, April 21, 2006 |
| APPL NO | 11/409259 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/122 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373088 | Yap et al. |
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| ASSIGNEE(S) | HRL Laboratories (Malibu, California) |
| INVENTOR(S) | Daniel Yap (Thousand Oaks, California); Keyvan Sayyah (Santa Monica, California) |
| ABSTRACT | An agile spread spectrum waveform generator comprises a photonic oscillator and an optical heterodyne synthesizer. The photonic oscillator comprises a multi-tone optical comb generator for generating a series of RF comb lines on an optical carrier. The optical heterodyne synthesizer includes first and second phase-locked lasers; the first laser feeding the multi-tone optical comb generator and the second laser comprising a rapidly wavelength-tunable single tone laser whose output light provides a frequency translation reference. A photodetector is provided for heterodyning the frequency translation reference with the optical output of the photonic oscillator to generate an agile spread spectrum waveform. |
| FILED | Friday, April 05, 2002 |
| APPL NO | 10/116829 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373105 | Dybdal et al. |
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| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Robert B. Dybdal (Palos Verdes Estates, California); Michael A. Rolenz (Harbor City, California) |
| ABSTRACT | A method of determining communication link quality includes the steps of: providing communications stations (e.g., UHF communications satellites, base stations of a terrestrial cellular network) with beacon transmitters that are used to transmit two types of signals from each communications station; and providing a communications device that employs the communications stations with beacon receivers and the ability to process the two types of signals to provide a user of the communications device with a real time determination of link impairments and, from this, a determination of the type and quality of service that is available to the user. The first type of signal is a stable continuous wave (CW) tone that provides a reference signal level, and the second type of signal is a coded waveform with distinguishable correlation properties. In an exemplary preferred embodiment, a processor and display are integrated with the user's communication device and function to process these two signals and provide a user-friendly interface through which information pertaining to determined levels of link impairments and the type and quality of service available at that given location and time is communicated to the user. In an exemplary preferred embodiment, the user's communication device is also provided with a booster system with an alternative high-gain antenna to increase communications opportunities in difficult operating environments. |
| FILED | Wednesday, November 07, 2001 |
| APPL NO | 10/007992 |
| ART UNIT | 2617 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/13.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373168 | Kumar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Rajendra Kumar (Cerritos, California) |
| ABSTRACT | A power controller in a communication system adjusts the transmitted power level using adaptive prediction of channel fading for maintaining the power level for improved communications by using an adaptive nonlinear predictor that explicitly takes into account the propagation delay and channel fading where the transmitted power is determined on the basis of the measurement of the received power levels over the individual diversity branches for providing communication through a fading channel with effective performance equivalent to that of a channel without any signal fading. |
| FILED | Wednesday, January 12, 2005 |
| APPL NO | 11/034170 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/522 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373260 | Kessler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Metis Design Corporation (Cambridge, Massachusetts) |
| INVENTOR(S) | Seth S. Kessler (Brookline, Massachusetts); Kristin A. Jugenheimer (Cambridge, Massachusetts); Aaron B. Size (Cambridge, Massachusetts) |
| ABSTRACT | A device for use in detecting an event in a structure includes a sensor encapsulation, the encapsulation containing a sensor, an actuator positioned substantially in-plane to the sensor within the housing and a printed circuit board in communication with at least one of the sensor and the actuator. The printed circuit board includes a microprocessor constructed and arranged to collect data from at least one of the sensor and the actuator, a signal generator constructed and arranged to provide excitation to at least one of the sensor and the actuator, and an amplifier to condition the excitation. |
| FILED | Thursday, March 03, 2005 |
| APPL NO | 11/071129 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373523 | Moritz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Elan Moritz (Lynn Haven, Florida) |
| ABSTRACT | Digital data is prepared for storage in a secure fashion. Each data byte of a data file is encrypted. A unique bit number is assigned to each data bit in the encrypted data bytes where the bit number identifies a position of the data bit in the data file. Each such bit number is encrypted to generate a corresponding encrypted bit number. A data package is generated for each data bit. The data package includes a first data byte containing (i) a value of the data bit, and (ii) a bit storage location, at least one second data byte identifying the data file with which the data bit is associated, and at least one third data byte containing the encrypted bit number associated with the data bit. Each data package is transmitted to one of a plurality of storage locations based on the bit storage location identified in the data package's first data byte. |
| FILED | Friday, April 23, 2004 |
| APPL NO | 10/834157 |
| ART UNIT | 2134 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 07370543 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Teh-Hsun B. Chen (Morgantown, West Virginia); Gregory Feather (Morgantown, West Virginia); Jvoti Keswani (Morgantown, West Virginia); Herbert David Edgell, III (Morgantown, West Virginia) |
| ABSTRACT | The present disclosure concerns embodiments of a sampling apparatus that utilizes one or more cyclone separators to collect airborne particles from the atmosphere. In one representative embodiment, the sampling apparatus includes a collection-vessel retaining member that is adapted to be removably coupled to a collection vessel. The retaining member has an air-inlet conduit for permitting air to flow through the open end of the collection vessel and an air-outlet conduit for permitting air to exit the open end of the collection vessel. The airinlet conduit and the air-outlet conduit are configured to cause air flowing into the collection vessel to establishes a cyclonic flow path, which causes airborne particles to separate out from the air stream and collect in the collection vessel. |
| FILED | Friday, October 01, 2004 |
| APPL NO | 10/575048 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/863.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371225 | Oldfield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Edward H. Oldfield (Philomont, Virginia); Russel R. Lonser (Silver Spring, Maryland); Kayhan Garmestani (Potomac, Maryland); Martin W. Brechbiel (Annandale, Virginia) |
| ABSTRACT | A method for monitoring and controlling convection enhanced delivery of a therapeutic agent to a target tissue is disclosed. A tracer that is detectable, for example, by magnetic resonance imaging (MRI) and/or by X-ray computed tomography (CT) is co-infused with the therapeutic agent and used to monitor the distribution of the therapeutic agent as it moves through the target tissue. The images obtained during delivery are used to confirm delivery of the therapeutic agent to the target tissue and to avoid exposure of tissue outside of the targeted area to the therapeutic agent. In addition, the signal intensity of the images may be used to confirm that the therapeutic agent has been delivered to the target tissue at a desired concentration. |
| FILED | Wednesday, September 24, 2003 |
| APPL NO | 10/528310 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Surgery 64/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371364 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Chun Li (Missouri City, Texas); Wei Wang (Sugar Land, Texas); Shi Ke (Missouri City, Texas) |
| ABSTRACT | The present invention relates to novel cyclic peptides that may be conjugated with imaging agents, including novel imaging agents. Specifically, it includes c(KRGDf; SEQ ID NO. 3) NIR imaging compositions and novel cyclic HWGFTL (SEQ ID NO. 5) polypeptides which may be used inter alia in NIR, MRI and nuclear imaging as well as therapy. Additionally, the invention includes novel imaging agents, such as TS-ICG derivatives. The invention also relates to methods of making and using such compounds. Such uses include both pre-operative and intraoperative detection of tumor cells and treatment monitoring. |
| FILED | Friday, August 13, 2004 |
| APPL NO | 10/918009 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371392 | Tripp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Ralph A. Tripp (Decatur, Georgia); Larry J. Anderson (Atlanta, Georgia); Michael P. Brown (St. Georges, Australia) |
| ABSTRACT | The present invention provides methods and adjuvants for enhancing an immune response to RSV in a host, wherein the methods and adjuvants comprise a source of a CD40 binding protein. Preferably, the CD40 binding protein is CD40L and the source is a vector comprising a promoter operatively linked to a CD40L coding region. The enhanced immune response produced by the adjuvants and methods of the current invention includes both increased expression of Th1 cytokines and increased production of antibody. |
| FILED | Friday, February 02, 2001 |
| APPL NO | 10/182093 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/211.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371399 | Prescott |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albert G. Prescott (Westford, Massachusetts) |
| ABSTRACT | Formulations and methods for treating joints, such as temporomandibular joint disorders, osteoarthritis of the knee, hip and other types of inflammatory joint diseases. The method involves identifying specific matrix metalloproteinases (MMPs) that may be responsible for degrading the soft tissues of the joint in question, identifying the specific component of the joint the MMP(s) are targeting, and injecting a polymer gel with the component the MMP(s) seek to destroy, thus preserving the joint and allowing time to heal. These formulations typically require a mixture of glycosoaminoglycans and collagen proteins. One formulation in particular includes both hyaluronic acid and at least type I collagen. |
| FILED | Thursday, July 14, 2005 |
| APPL NO | 11/181107 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371513 | Steinhardt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard A. Steinhardt (Berkeley, California) |
| ABSTRACT | Tissue preservation media comprising a polyoxyethylene/polyoxypropylene copolymer are used to preserve tissues and organs for storage and transplantation. In particular embodiments, the polyoxyethylene/polyoxypropylene copolymer is Pluronic F68 or FLOCOR (CRL-5861; purified poloxamer 188), and the medium is Steinhardt medium, polyoxyethylene/polyoxypropylene copolymer-supplemented Optisol GS or polyoxyethylene/polyoxypropylene copolymer-supplemented ViaSpan. |
| FILED | Friday, December 17, 2004 |
| APPL NO | 11/015180 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371522 | Williams, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Redford B. Williams, Jr. (Hillsborough, North Carolina) |
| ABSTRACT | The present invention provides a method of screening subjects for disease risk. The method comprises determining the serotonin transporter gene promoter genotype of a subject. The serotonin transporter gene promoter genotype is used to indicate whether or not the subject is at increased risk of disease. The method is particularly adapted to screening for risk of disease in response to stress, and accordingly can be used to indicate interventions that manage stress, and hence reduce disease risk, in susceptible or higher-risk individuals. |
| FILED | Wednesday, July 23, 2003 |
| APPL NO | 10/625134 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371523 | Thomae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Bianca A. Thomae (Bay Village, Ohio); Eric D. Wieben (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota); Yuan Ji (Rochester, Minnesota) |
| ABSTRACT | Isolated PNMT nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as PNMT allozymes. Methods for determining if a subject is predisposed to multiple sclerosis, early-onset Alzheimer's disease, or Parkinson's disease also are described. |
| FILED | Friday, January 09, 2004 |
| APPL NO | 10/755018 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371527 | Baylin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Johns Hopkins University School of Medicine (Baltimore, Maryland) |
| INVENTOR(S) | Stephen B. Baylin (Baltimore, Maryland); Yoshimitsu Akiyama (Chiba, Japan); James G. Herman (Lutherville, Maryland) |
| ABSTRACT | Methods are provided for identifying the presence of cancer cells in a sample by detecting hypermethylation of the promoter region of a GATA-4 transcription factor gene, a GATA-5 transcription factor gene, or both. Methods for ameliorating a cancer by effecting expression of a hypermethylation silenced GATA-4 and/or GATA-5 transcription also are provided. |
| FILED | Thursday, October 21, 2004 |
| APPL NO | 10/972066 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371529 | Spiegelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Clifford Hyunsuk Yoon (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides novel methods and compositions for modulating gluconeogenesis through modulation of PGC-1 activity or expression. Also provided are methods for identifying compounds that modulate gluconeogenesis through modulation of PGC-1 activity or expression, as well as methods for identifying compounds that modulate the interaction of PGC-1 with PGC-1 target molecules. Further provided are methods for treating disorders characterized by aberrant gluconeogenesis. |
| FILED | Thursday, January 06, 2005 |
| APPL NO | 11/031450 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371533 | Slater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Ottawa (Ottawa, Canada); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Gary W. Slater (Ottawa, Canada); Laurette C. McCormick (Chambly, Canada); Annelise E Barron (Evanston, Illinois); Robert J. Meagher (Mountain House, California) |
| ABSTRACT | Recently two techniques using free solution electrophoresis to separate charged-uncharged polymer conjugates have proven successful: End Labeled Free Solution Electrophoresis (ELFSE) for DNA sequencing, and Free Solution Conjugate Electrophoresis (FSCE) for molar mass profiling of uncharged polymers. Previous attempts have been made to analyze experimental data generated by these new techniques for the electrophoresis of molecules with varying charge distributions. However, the importance of the ends of the polymers in determining the polymer's overall mobility was neglected in previous work. Through a careful investigation and a reanalysis of the experimental data, it is determined here that this “end effect” critically impacts the behavior of polymers and charged-uncharged polymer conjugates during electrophoresis. In this way, the invention provides for methods that exploit this “end effect” for the separation of polymeric molecules on the basis of size, including for example DNA separation and sequencing techniques. |
| FILED | Tuesday, October 04, 2005 |
| APPL NO | 11/241990 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371539 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Daniel M. Janse (Brookline, Massachusetts) |
| ABSTRACT | This invention pertains to compositions, methods, cells and organisms useful for selectively localizing polypeptides to the proteasome for degradation. Therapeutic methods and pharmaceutical compositions for treating disorders associated with the expression and/or activity of a polypeptide by targeting these polypeptides for degradation, as well as methods for targeting therapeutic polypeptides for degradation and/or activating therapeutic polypeptides by degradation are provided. The invention provides methods for identifying compounds that mediate proteasome localization and/or polypeptide degradation. The invention also provides research tools for the study of protein function. |
| FILED | Friday, December 03, 2004 |
| APPL NO | 11/003103 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371571 | Barletta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents University of Nebraska - Lincoln (Lincoln, Nebraska) |
| INVENTOR(S) | Raul G. Barletta (Lincoln, Nebraska); Zhengyu Feng (Austin, Texas) |
| ABSTRACT | Recombinant mycobacterial strains which overproduce essential biosynthetic enzymes of pathogenic mycobateria are provided. These strains overproduce enzymes involved in the synthesis and incorporation of |
| FILED | Wednesday, December 17, 2003 |
| APPL NO | 10/738938 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371575 | Kale et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Sujata Kale (Boston, Massachusetts); Michael W. Long (Northville, Michigan) |
| ABSTRACT | The present invention concerns methods for the ex vivo formation of mammalian bone and subsequent uses of the bone. A critical and distinguishing feature of the present invention are defined tissue culture conditions and factors resulting in the formation of bone cell spheroids. The invention also provides for methods of implanting into subjects the ex vivo formed bone. Also described are methods for genetically altering the bone cell spheroids to affect bone formation, identification of candidate modulators of bone formation, and identification of genes involved in bone formation. |
| FILED | Tuesday, June 08, 2004 |
| APPL NO | 10/862972 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/372 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371579 | Rokita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Steven E. Rokita (Silver Spring, Maryland); Cynthia J. Burrows (Salt Lake City, Utah) |
| ABSTRACT | The invention relates to a compound comprising a labeled nickel complex (FIG. 1) that is used to detect and purify nucleic acid sequences by forming an adduct between a specific nucleic acid base and the labeled nickel complex. The adduct can also be purified through a separation process, such as affinity chromatography |
| FILED | Monday, July 03, 2000 |
| APPL NO | 10/019655 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371733 | Chang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Utah State University (Logan, Utah) |
| INVENTOR(S) | Cheng-Wei Tom Chang (Logan, Utah) |
| ABSTRACT | The invention relates to novel paranmycin compounds that have activity against gram positive and gram negative bacteria, preferably bacteria that are resistant to other antibiotics. Paranmycins are of the general formula |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385641 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/38 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371736 | Shaughnessy et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | John D. Shaughnessy (Little Rock, Arkansas); Bart Barlogie (Little Rock, Arkansas); Fenghuang Zhan (Little Rock, Arkansas) |
| ABSTRACT | Gene expression profiling reveals four distinct subgroups of multiple myeloma that have significant correlation with various clinical characteristics. Diagnosis for multiple myeloma (and possibly monoclonal gammopathy of undetermined significance) based on differential expression of 14 genes, as well as prognosis for the four subgroups of multiple myeloma based on the expression of 24 genes are established. A 15-gene model that classifies myeloma into 7 groups is also reported. Gene expression profiling also allows placing multiple myeloma into a developmental schema parallel to that of normal plasma cell differentiation. Development of a gene expression- or developmental stage-based classification system for multiple myeloma would lead to rational design of more accurate and sensitive diagnostics, prognostics and tumor-specific therapies for multiple myeloma. |
| FILED | Wednesday, September 01, 2004 |
| APPL NO | 10/931780 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371745 | Ebright et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard H. Ebright (North Brunswick, New Jersey); Yon W. Ebright (North Brunswick, New Jersey) |
| ABSTRACT | A molecule for labeling a target material is provided including two transition-metal chelates and a detectable group. The molecule has the general structural formula (I): wherein: (a) Y and Y′ are each a transition metal, (b) R1 and R1′ are each independently CH(COO−), CH(COOH), or absent; (c) R2 and R2′ are linkers each having a length of from about 3.0 to about 20 Å; and (d) X is a detectable group. The linkers may be linear or branched, may contain aromatic moieties, and may optionally be further substituted. Methods of using the molecules of the invention as probes in detecting and analyzing target materials as well as kits including the molecule of the invention are also provided. |
| FILED | Tuesday, September 21, 2004 |
| APPL NO | 10/946786 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/229.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371809 | Brandt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
| ABSTRACT | This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and nonenveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections. |
| FILED | Tuesday, February 06, 2001 |
| APPL NO | 09/777560 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371841 | Julius et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David Julius (San Francisco, California); David D. McKemy (Livermore, California); Werner M. Neuhausser (San Francisco, California) |
| ABSTRACT | The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein family, CMR1, which is involved in modulation of the perception of cold sensations and pain. The invention further relates to methods for identifying and using agents that modulate cold responses and pain responses stimulated by cold via modulation of CMR1 and CMR1-related signal transduction. |
| FILED | Monday, January 27, 2003 |
| APPL NO | 10/352724 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371846 | Hoxie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James A. Hoxie (Berwyn, Pennsylvania); Celia C. LaBranche (Chapel Hill, North Carolina); Robert W. Doms (Berwyn, Pennsylvania); Trevor L. Hoffman (Lansdowne, Pennsylvania) |
| ABSTRACT | The invention relates to novel CD4-independent HIV Envelope proteins and uses therefor. |
| FILED | Tuesday, February 01, 2005 |
| APPL NO | 11/048554 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.720 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372021 | Cotter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Robert James Cotter (Baltimore, Maryland); Benjamin D. Gardner (Owings Mills, Maryland); John F Holland (Haslett, Michigan) |
| ABSTRACT | A time-of-flight mass spectrometer which has an iron source, an evacuated tube proximate the ion source and adapted to receive ions from the ion source, and a detector disposed at an end of the evacuated tube opposite an end proximate the ion source. The ion source is constructed to generate an electric field that changes non-linearly as a function of position along a path from the ion source to the detector. The ion source is constructed to generate an electric field that changes as a function of time, the electric field being provided to accelerate ions from the ion source to the detector. |
| FILED | Monday, February 13, 2006 |
| APPL NO | 11/352301 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372270 | Sung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | KyungHyun Sung (Los Angeles, California); Krishna Nayak (Los Angeles, California) |
| ABSTRACT | A method and system are described for compensating for non-uniformity of excitation field B1+ in magnetic resonance imaging (MRI) of an object. The variation in the RF excitation field B1+ is measured over a region of interest (ROI) in the object, the B1+ field causing nuclear spins in the object to flip at a flip angle when B1+ is applied to the object. The flip angle profile is designed to be proportional to a reciprocal of the measured variation in the excitation field B1+. One or more control parameters of the estimated flip angle profile is adjusted, in accordance with the measured variation in B1+, so as to cancel out variation in actual flip angle until a profile of the actual flip angle is achieved that is substantially uniform throughout the ROI. |
| FILED | Tuesday, September 12, 2006 |
| APPL NO | 11/531090 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/314 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372937 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Kowa City, Iowa) |
| INVENTOR(S) | Ge Wang (Iowa City, Iowa); Yangbo Ye (Coralville, Iowa) |
| ABSTRACT | Provided herein are methods of reconstructing an image from projection data provided by a tomography scanner that is based on geometric optics comprising scanning an object in a cone-beam imaging geometry following a non-standard spiral path or a general piecewise smooth scanning path wherein projection data is generated and reconstructing an image according to a closed-form formula that is either in the filtered backprojection (FBP) or backprojection filtration (or backprojected filtration, BPF) formats. Also provided herein are associated systems and apparatuses for tomographic imaging. |
| FILED | Friday, July 15, 2005 |
| APPL NO | 11/182504 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372985 | So et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter So (Cambridge, Massachusetts); Bevin Engelward (Jamacia Plain, Massachusetts); Timothy Ragan (Cambridge, Massachusetts); Karsten Bahlmann (Cambridge, Massachusetts); Ki Hean Kim (Cambridge, Massachusetts); Lily Hsu (Arlington, Massachusetts); Hayden Huang (Somerville, Massachusetts) |
| ABSTRACT | In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two photons into a region of interest, scanning the region of interest across a portion of the tissue, imaging a plurality of layers of the tissue in a plurality of volumes of the tissue in the region of interest, sectioning the portion of the tissue and imaging a second plurality of layers of the tissue in a second plurality of volumes of the tissue in the region of interest, detecting a fluorescence image of the tissue due to said excitation light; and processing three-dimensional data that is collected to create a three-dimensional image of the region of interest. |
| FILED | Friday, August 15, 2003 |
| APPL NO | 10/642447 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373199 | Sackellares et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Arizona Board of Regents (Tempe, Arkansas) |
| INVENTOR(S) | James Chris Sackellares (Gainesville, Florida); Leonidas D. Iasemidis (Scottsdale, Arizona); Deng-Shan Shiau (Gainesville, Florida); Linda Dance (Gainesville, Florida) |
| ABSTRACT | Characterizing the behavior of a chaotic, multi-dimensional system is achieved by measuring each of a number of signals associated with the system, and generating therefrom, a spatio-temporal response based on each signal. Chaoticity profiles are then generated for each spatio-temporal response. Over a period of time, a determination is made as to whether a certain level of dynamic entrainment and/or disentrainment exists between the chaoticity profiles associated with one or more critical channel groups of a selected predictor, where a predictor represents a given number of critical channel groups “x”, a given number of channels per group “y”, and a total number of channels N. Characterizing the behavior of the system is based on this determination. |
| FILED | Wednesday, August 27, 2003 |
| APPL NO | 10/648354 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07370511 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | MST Technology GmbH (, Germany) |
| INVENTOR(S) | Ing-Shin Chen (Danbury, Connecticut); Frank Dimeo, Jr. (Danbury, Connecticut); Philip S. H. Chen (Bethel, Connecticut); Jeffrey W. Neuner (Bethel, Connecticut); James Welch (Fairfield, Connecticut); Bryan Hendrix (Danbury, Connecticut) |
| ABSTRACT | A sensor with an attenuated drift characteristic, including a layer structure in which a sensing layer has a layer of diffusional barrier material on at least one of its faces. The sensor may for example be constituted as a hydrogen gas sensor including a palladium/yttrium layer structure formed on a micro-hotplate base, with a chromium barrier layer between the yttrium layer and the micro-hotplate, and with a tantalum barrier layer between the yttrium layer and an overlying palladium protective layer. The gas sensor is useful for detection of a target gas in environments susceptible to generation or incursion of such gas, and achieves substantial (e.g., >90%) reduction of signal drift from the gas sensor in extended operation, relative to a corresponding gas sensor lacking the diffusional barrier structure of the invention. |
| FILED | Monday, March 08, 2004 |
| APPL NO | 10/795529 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/23.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07370524 | Hopkins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | David James Hopkins (Livermore, California) |
| ABSTRACT | A control system and method for actively reducing vibration in a spindle housing caused by unbalance forces on a rotating spindle, by measuring the force-induced spindle-housing motion, determining control signals based on synchronous demodulation, and provide compensation for the measured displacement to cancel or otherwise reduce or attenuate the vibration. In particular, the synchronous demodulation technique is performed to recover a measured spindle housing displacement signal related only to the rotation of a machine tool spindle, and consequently rejects measured displacement not related to spindle motion or synchronous to a cycle of revolution. Furthermore, the controller actuates at least one voice-coil (VC) motor, to cancel the original force-induced motion, and adapts the magnitude of voice coil signal until this measured displacement signal is brought to a null. In order to adjust the signal to a null, it must have the correct phase relative to the spindle angle. The feedback phase signal is used to adjust a common (to both outputs) commutation offset register (offset relative to spindle encoder angle) to force the feedback phase signal output to a null. Once both of these feedback signals are null, the system is compensating properly for the spindle-induced motion. |
| FILED | Monday, August 15, 2005 |
| APPL NO | 11/205551 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/146.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07370613 | Lawrence et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Keith Edward Lawrence (Kobe, Japan); William Elliott Moser (Peoria, Illinois); Stephan Donald Roozenboom (Washington, Illinois); Kevin Jay Knox (Peoria, Illinois) |
| ABSTRACT | A variable compression ratio mechanism for an internal combustion engine that has an engine block and a crankshaft is disclosed. The variable compression ratio mechanism has a plurality of eccentric disks configured to support the crankshaft. Each of the plurality of eccentric disks has at least one cylindrical portion annularly surrounded by the engine block. The variable compression ratio mechanism also has at least one actuator configured to rotate the plurality of eccentric disks. |
| FILED | Tuesday, November 30, 2004 |
| APPL NO | 10/998895 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/48.B00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07370716 | Hickam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Christopher Dale Hickam (Glasford, Illinois) |
| ABSTRACT | A motor/generator is provided for connecting between a transmission input shaft and an output shaft of a prime mover. The motor/generator may include a motor/generator housing, a stator mounted to the motor/generator housing, a rotor mounted at least partially within the motor/generator housing and rotatable about a rotor rotation axis, and a transmission-shaft coupler drivingly coupled to the rotor. The transmission-shaft coupler may include a clamp, which may include a base attached to the rotor and a plurality of adjustable jaws. |
| FILED | Wednesday, June 01, 2005 |
| APPL NO | 11/141064 |
| ART UNIT | 3618 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Motor vehicles 180/65.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371310 | Griffiths et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Livermore, California) |
| INVENTOR(S) | Stewart K. Griffiths (Livermore, California); Robert H. Nilson (Cardiff, California) |
| ABSTRACT | The present invention improves the performance of microchannel systems for chemical and biological synthesis and analysis by providing a method and apparatus for producing a thin band of a species sample. Thin sample bands improve the resolution of microchannel separation processes, as well as many other processes requiring precise control of sample size and volume. The new method comprises a series of steps in which a species sample is manipulated by controlled transport through a junction formed at the intersection of four or more channels. A sample is first inserted into the end of one of these channels in the vicinity of the junction. Next, this sample is thinned by transport across the junction one or more times. During these thinning steps, flow enters the junction through one of the channels and exists through those remaining, providing a divergent flow field that progressively stretches and thins the band with each traverse of the junction. The thickness of the resulting sample band may be smaller than the channel width. Moreover, the thickness of the band may be varied and controlled by altering the method alone, without modification to the channel or junction geometries. The invention is applicable to both electroosmotic and electrophoretic transport, to combined electrokinetic transport, and to some special cases in which bulk fluid transport is driven by pressure gradients. It is further applicable to channels that are open, filled with a gel or filled with a porous or granular material. |
| FILED | Monday, April 05, 2004 |
| APPL NO | 10/818609 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/604 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371353 | Robel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Wade J. Robel (Peoria, Illinois); James Joshua Driscoll (Dunlap, Illinois); Gerald N. Coleman (Peterborough, United Kingdom) |
| ABSTRACT | A system of ammonia production for a selective catalytic reduction system is provided. The system includes producing an exhaust gas stream within a cylinder group, wherein the first exhaust gas stream includes NOx. The exhaust gas stream may be supplied to an exhaust passage and cooled to a predetermined temperature range, and at least a portion of the NOx within the exhaust gas stream may be converted into ammonia. |
| FILED | Wednesday, August 31, 2005 |
| APPL NO | 11/216359 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/180 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371533 | Slater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Ottawa (Ottawa, Canada); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Gary W. Slater (Ottawa, Canada); Laurette C. McCormick (Chambly, Canada); Annelise E Barron (Evanston, Illinois); Robert J. Meagher (Mountain House, California) |
| ABSTRACT | Recently two techniques using free solution electrophoresis to separate charged-uncharged polymer conjugates have proven successful: End Labeled Free Solution Electrophoresis (ELFSE) for DNA sequencing, and Free Solution Conjugate Electrophoresis (FSCE) for molar mass profiling of uncharged polymers. Previous attempts have been made to analyze experimental data generated by these new techniques for the electrophoresis of molecules with varying charge distributions. However, the importance of the ends of the polymers in determining the polymer's overall mobility was neglected in previous work. Through a careful investigation and a reanalysis of the experimental data, it is determined here that this “end effect” critically impacts the behavior of polymers and charged-uncharged polymer conjugates during electrophoresis. In this way, the invention provides for methods that exploit this “end effect” for the separation of polymeric molecules on the basis of size, including for example DNA separation and sequencing techniques. |
| FILED | Tuesday, October 04, 2005 |
| APPL NO | 11/241990 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371538 | Simpson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Michael L. Simpson (Knoxville, Tennessee); Michael J. Paulus (Knoxville, Tennessee); Gary S. Sayler (Blaine, Tennessee); Bruce M. Applegate (West Lafayette, Indiana); Steven A. Ripp (Knoxville, Tennessee) |
| ABSTRACT | An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on the chip for processing the photocurrent. A distributed electrode configuration including a plurality of spaced apart electrodes disposed on an active region of the photodetector is preferably used to raise efficiency. |
| FILED | Tuesday, June 14, 2005 |
| APPL NO | 11/151964 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371539 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Daniel M. Janse (Brookline, Massachusetts) |
| ABSTRACT | This invention pertains to compositions, methods, cells and organisms useful for selectively localizing polypeptides to the proteasome for degradation. Therapeutic methods and pharmaceutical compositions for treating disorders associated with the expression and/or activity of a polypeptide by targeting these polypeptides for degradation, as well as methods for targeting therapeutic polypeptides for degradation and/or activating therapeutic polypeptides by degradation are provided. The invention provides methods for identifying compounds that mediate proteasome localization and/or polypeptide degradation. The invention also provides research tools for the study of protein function. |
| FILED | Friday, December 03, 2004 |
| APPL NO | 11/003103 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371719 | Stupp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Jeffrey D. Hartgerink (Pearland, Texas); Elia Beniash (Auburndale, Massachusetts) |
| ABSTRACT | Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/368517 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371887 | Stupp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); James F. Hulvat (Chicago, Illinois); Marina Sofos (Evanston, Illinois); Keisuke Tajima (Evanston, Illinois) |
| ABSTRACT | Amphiphilic oligo(p-phenylene vinylene) compounds and methods of use en route to self-assembled composites and device fabrication. |
| FILED | Monday, December 06, 2004 |
| APPL NO | 11/005558 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 560/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371907 | Lokshin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Konstantin Lokshin (Santa Fe, New Mexico); Yusheng Zhao (Los Alamos, New Mexico) |
| ABSTRACT | The present invention includes a method for hydrogen clathrate hydrate synthesis. First, ice and hydrogen gas are supplied to a containment volume at a first temperature and a first pressure. Next, the containment volume is pressurized with hydrogen gas to a second higher pressure, where hydrogen clathrate hydrates are formed in the process. |
| FILED | Wednesday, July 07, 2004 |
| APPL NO | 10/886229 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372059 | Shumlak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Washington (Seattle, Washington) |
| INVENTOR(S) | Uri Shumlak (Seattle, Washington); Raymond Golingo (Seattle, Washington); Brian A. Nelson (Mountlake Terrace, Washington) |
| ABSTRACT | Various mechanisms are provided relating to plasma-based light source that may be used for lithography as well as other applications. For example, a device is disclosed for producing extreme ultraviolet (EUV) light based on a sheared plasma flow. The device can produce a plasma pinch that can last several orders of magnitude longer than what is typically sustained in a Z-pinch, thus enabling the device to provide more power output than what has been hitherto predicted in theory or attained in practice. Such power output may be used in a lithography system for manufacturing integrated circuits, enabling the use of EUV wavelengths on the order of about 13.5 nm. Lastly, the process of manufacturing such a plasma pinch is discussed, where the process includes providing a sheared flow of plasma in order to stabilize it for long periods of time. |
| FILED | Monday, October 17, 2005 |
| APPL NO | 11/252021 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/504.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372709 | Mazumder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Chicago, Illinois) |
| INVENTOR(S) | Sudip K. Mazumder (Chicago, Illinois); Rajni K. Burra (Chicago, Illinois); Kaustuva Acharya (Chicago, Illinois) |
| ABSTRACT | Apparatus for conditioning power generated by an energy source includes an inverter for converting a DC input voltage from the energy source to a square wave AC output voltage, and a converter for converting the AC output voltage from the inverter to a sine wave AC output voltage. |
| FILED | Monday, September 19, 2005 |
| APPL NO | 11/230312 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electric power conversion systems 363/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373612 | Risch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | John S. Risch (Kennewick, Washington); Scott T. Dowson (West Richland, Washington); Michelle L. Hart (Richland, Washington); Wes L. Hatley (Kennewick, Washington) |
| ABSTRACT | A method of displaying correlations among information objects comprises receiving a query against a database; obtaining a query result set; and generating a visualization representing the components of the result set, the visualization including one of a plane and line to represent a data field, nodes representing data values, and links showing correlations among fields and values. Other visualization methods and apparatus are disclosed. |
| FILED | Monday, October 20, 2003 |
| APPL NO | 10/690307 |
| ART UNIT | 2173 — Graphical User Interface and Document Processing |
| CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/850 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07371359 | Paine, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Robert T. Paine, Jr. (Albuquerque, New Mexico) |
| ABSTRACT | A non-aqueous route and process for preparation of boron nitride utilizing aerosol assisted vapor phase synthesis (AAVS) wherein boron precursors are nitrided in one or two heating steps, and wherein a boron oxide nitride carbide intermediary composition is formed after the first heating step and may be further nitrided to form resultant spheroidal boron nitride powders including dense or hollow spheroidal particles that are smooth, bladed, dense or hollow, have protruding whiskers, and are of turbostratic or hexagonal crystalline structure, specifically wherein the boron precursor is dissolved in a non-aqueous solution prior to aerosolization. |
| FILED | Monday, February 12, 2007 |
| APPL NO | 11/673849 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371457 | Oldenburg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rich University (Houston, Texas) |
| INVENTOR(S) | Steven J. Oldenburg (Houston, Texas); Richard D. Averitt (Houston, Texas); Nancy J. Halas (Houston, Texas) |
| ABSTRACT | The present invention is for particulate compositions and methods for producing them that can absorb or scatter electromagnetic radiation. The particles are homogeneous in size and are comprised of a nonconducting inner layer that is surrounded by an electrically conducting material. The ratio of the thickness of the nonconducting layer to the thickness of the outer conducting shell is determinative of the wavelength of maximum absorbance or scattering of the particle. Unique solution phase methods for synthesizing the particles involve linking clusters of the conducting atoms, ions, or molecules to the nonconducting inner layer by linear molecules. This step can be followed by growth of the metal onto the clusters to form a coherent conducting shell that encapsulates the core. |
| FILED | Tuesday, January 06, 2004 |
| APPL NO | 10/752181 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Stock material or miscellaneous articles 428/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371719 | Stupp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Jeffrey D. Hartgerink (Pearland, Texas); Elia Beniash (Auburndale, Massachusetts) |
| ABSTRACT | Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/368517 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372480 | Lavrentovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Kent State University (Kent, Ohio) |
| INVENTOR(S) | Oleg D. Lavrentovich (Kent, Ohio); Dmitry Voloschenko (Schaumburg, Illinois); Sergij Shiyanovskii (Kent, Ohio) |
| ABSTRACT | A liquid crystal device comprises a first and second cell wall structure; at least one liquid crystal material disposed within a space between the first and second cell wall structures; and polymer micro-structures, wherein the micro-structures are formed by polymerizing a prepolymer, and wherein said micro-structures have a shape and spatial location determined by said liquid crystal material. Permanent polymer micro-structures are formed from a liquid crystal with a non-uniform spatially modulated director field. The polymer structures have the shape and spatial location dictated by the non-uniform director field of the liquid crystal. The micro-structures are a backbone that restores the liquid crystal director field that existed during the polymerization process even when other factors, such as electric field, temperature, or surface anchoring, do not favor this restoration. The polymer micro-structures can be used in optical devices, such as diffraction gratings and deflecting and beam steering devices, and in micro-mechanical and micro-fluidic devices. |
| FILED | Tuesday, December 07, 2004 |
| APPL NO | 11/005779 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Television 348/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373291 | Garst |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mathsoft Engineering and Education, Inc. (Needham, Massachusetts) |
| INVENTOR(S) | Peter F. Garst (Palo Alto, California) |
| ABSTRACT | The present invention provides a new source of information, linguistic models, to improve the accuracy of mathematical recognition. Specifically, the present invention is an extension of linguistic methods to the mathematical domain thereby providing recognition of the artificial language of mathematics in a way analogous to natural language recognition. Parse trees are the basic units of the mathematical language, and a linguistic model for mathematics is a method for assigning a linguistic score to each parse tree. The models are generally created by taking a large body of known text and counting the occurrence of various linguistic events such as word bigrams in that body. The raw counts are modified by smoothing and other algorithms before taking their place as probabilities in the model. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/368766 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373451 | Lam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Monica Sin-Ling Lam (Menlo Park, California); Constantine Paul Sapuntzakis (Mountain View, California); Ramesh U. V. Chandra (Palo Alto, California); Nickolai Borisovich Zeldovich (Stanford, California); Mendel Rosenblum (Stanford, California); James Eugene Chow (San Jose, California); David James Brumley (Pittsburgh, Pennsylvania) |
| ABSTRACT | A cache-based system management architecture named “the Collective” automates system management and supports mobile computing. The Collective manages systems by manipulating virtual appliances, each encapsulating a system state. A virtual appliance (VA) may comprise a virtual network of VAs. Distributed repositories separately storing the VAs and user data. Publishers create and maintain VAs. A user plugs a bootable portable storage device implementing a VA transceiver (VAT) into a host computer. The VAT, comprising a Manager, a Cache Client, and a virtual machine monitor (VMM), authenticates the user, retrieves a copy of the latest version of a subscribed VA from the appropriate network repository, obtains user data, and automatically backs up the user data over the network in the background while running the subscribed VA. Multiple VAs can be run at the same time. With the novel caching protocol and cache charging process, the Collective performs well and has numerous advantages. |
| FILED | Wednesday, December 08, 2004 |
| APPL NO | 11/007911 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07370817 | Tilton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Isothermal Systems Research Inc. (Liberty Lake, Washington) |
| INVENTOR(S) | Charles Tilton (Colton, Washington); Jeff Weiler (Liberty Lake, Washington); Randall Palmer (Kendrick, Idaho); Philip Appel (Liberty Lake, Washington) |
| ABSTRACT | An actuated atomizer is adapted for spray cooling or other applications wherein a well-developed, homogeneous and generally conical spray mist is required. The actuated atomizer includes an outer shell formed by an inner ring; an outer ring; an actuator insert and a cap. A nozzle framework is positioned within the actuator insert. A base of the nozzle framework defines swirl inlets, a swirl chamber and a swirl chamber. A nozzle insert defines a center inlet and feed ports. A spool is positioned within the coil housing, and carries the coil windings having a number of turns calculated to result in a magnetic field of sufficient strength to overcome the bias of the spring. A plunger moves in response to the magnetic field of the windings. A stop prevents the pintle from being withdrawn excessively. A pintle, positioned by the plunger, moves between first and second positions. In the first position, the head of the pintle blocks the discharge passage of the nozzle framework, thereby preventing the atomizer from discharging fluid. In the second position, the pintle is withdrawn from the swirl chamber, allowing the atomizer to release atomized fluid. A spring biases the pintle to block the discharge passage. The strength of the spring is overcome, however, by the magnetic field created by the windings positioned on the spool, which withdraws the plunger into the spool and further compresses the spring. |
| FILED | Thursday, October 24, 2002 |
| APPL NO | 10/281391 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/585.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371358 | Upchurch, legal representative et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Wilhelmina H. Upchurch, legal representative (Virginia Beach, Virginia); David R. Schryer (Hampton, Virginia) |
| ABSTRACT | The present invention utilizes two precious metals with two to five different metal-oxides in a layered matrix to convert CO, HCs, and NOx to CO2, and N2 by oxidation of two components and reduction of the other in a moderately high temperature gaseous environment containing excess oxygen. |
| FILED | Monday, October 25, 2004 |
| APPL NO | 10/975117 |
| ART UNIT | 1754 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/213.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371784 | Guillot et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Alliant Techsystems Inc. (Edina, Minnesota) |
| INVENTOR(S) | David G. Guillot (Tremonton, Utah); Albert R. Harvey (Brigham City, Utah) |
| ABSTRACT | A novel and improved EPDM formulation for a solid propellant rocket motor is described wherein hexadiene EPDM monomer components are replaced by alkylidene norbornene components, and, with appropriate adjustment of curing and other additives, functionally required rheological and physical characteristics are achieved with the desired compatibility with any one of a plurality of solid filler materials, e.g., powder silica, carbon fibers or aramid fibers, and with appropriate adhesion and extended storage or shelf-life characteristics. |
| FILED | Tuesday, August 31, 2004 |
| APPL NO | 10/931778 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 523/138 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372408 | Gaucher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Brian P. Gaucher (Brookfield, Connecticut); Janusz Grzyb (Ossining, New York); Duixian Liu (Scarsdale, New York); Ullrich R. Pfeiffer (Yorktown Heights, New York) |
| ABSTRACT | Apparatus and methods are provided for packaging IC chips together with integrated antenna modules designed to provide a closed EM (electromagnetic) environment for antenna radiators, thereby allowing antennas to be designed independent from the packaging technology. |
| FILED | Friday, January 13, 2006 |
| APPL NO | 11/332737 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373359 | Hill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Matthew L. Hill (Yonkers, New York); Yuan-Chi Chang (White Plains, New York); Chung-Sheng Li (Ossining, New York); Vittorio Castelli (White Plains, New York); Lawrence David Bergman (Mount Kisco, New York) |
| ABSTRACT | An object tracking technique is provided which, given: (i) a potentially large data set; (ii) a set of dimensions along which the data has been ordered; and (iii) a set of functions for measuring the similarity between data elements, a set of objects are produced. Each of these objects is defined by a list of data elements. Each of the data elements on this list contains the probability that the data element is part of the object. The method produces these lists via an adaptive, knowledge-based search function which directs the search for high-probability data elements. This serves to reduce the number of data element combinations evaluated while preserving the most flexibility in defining the associations of data elements which comprise an object. |
| FILED | Wednesday, January 12, 2005 |
| APPL NO | 11/034288 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/102 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07371258 | Woo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | St. Jude Medical, Inc. (St. Paul, Minnesota) |
| INVENTOR(S) | Yi-Ren Woo (Woodbury, Minnesota); Abhay S. Pandit (Minneapolis, Minnesota) |
| ABSTRACT | An implantable prosthesis can be formed from an improved biocompatible material that provides for cellular colonization of the biocompatible material. Specifically, the biocompatible material is a rigid porous material. In embodiments of particular interest, the implantable prosthesis is a mechanical heart valve prosthesis with a rigid occluder. In some embodiments, the rigid occluder is formed from the biocompatible material. A filler comprising a hydrogel or a structural protein can be located within the pores. In some embodiments, a bioactive agent is within the pores. In some embodiments, the rigid occluder is formed from a polymer material, a carbonaceous solid or a ceramic material. The pores can extend through the rigid material. |
| FILED | Friday, October 26, 2001 |
| APPL NO | 10/004504 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Prosthesis 623/2.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371605 | Katz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Howard Edan Katz (Summit, New Jersey); Masato Ofuji (Kanagawa, Japan) |
| ABSTRACT | Techniques for disposing an organic semiconductor film on a receiver substrate, comprising the steps of: depositing an organic semiconductor film onto a donor substrate, the semiconductor film having a first surface facing the donor substrate and having an exposed second surface; bringing the exposed second surface adjacent a receiver substrate such that the semiconductor film is in contact with both substrates; and then, moving the donor and receiver substrates apart; and wherein a surface portion of the receiver substrate is maintained above its glass transition during the moving step. Active organic semiconductor devices. |
| FILED | Thursday, March 31, 2005 |
| APPL NO | 11/095014 |
| ART UNIT | 2823 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372071 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
| INVENTOR(S) | Yuning Li (Mississauga, Canada); Yiliang Wu (Mississauga, Canada); Beng S. Ong (Mississauga, Canada); Ping Liu (Mississauga, Canada) |
| ABSTRACT | An electronic device, such as a thin film transistor containing a semiconductor of, for example, of the Formula (I) wherein R represents alkyl, alkoxy, aryl, heteroaryl or a suitable hydrocarbon; each R1 and R2 is independently hydrogen (H), a suitable hydrocarbon; a heteroatom containing group or a halogen; R3 and R4 are independently a suitable hydrocarbon, a heteroatom containing group, or a halogen; x and y represent the number of groups; Z represents sulfur, oxygen, selenium, or NR′ wherein R′ is hydrogen, alkyl, or aryl; and n and m represent the number of repeating units. |
| FILED | Thursday, April 06, 2006 |
| APPL NO | 11/398981 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07371571 | Barletta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents University of Nebraska - Lincoln (Lincoln, Nebraska) |
| INVENTOR(S) | Raul G. Barletta (Lincoln, Nebraska); Zhengyu Feng (Austin, Texas) |
| ABSTRACT | Recombinant mycobacterial strains which overproduce essential biosynthetic enzymes of pathogenic mycobateria are provided. These strains overproduce enzymes involved in the synthesis and incorporation of |
| FILED | Wednesday, December 17, 2003 |
| APPL NO | 10/738938 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371922 | Wheeler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Matthew B. Wheeler (Tolono, Illinois); Brett R. White (Lincoln, Nebraska) |
| ABSTRACT | Provided is a method for the production of transgenic animals, especially pigs, by the use of nuclear transfer from genetically modified or other embryonic stem cells to either enucleated oocytes which were matured in vivo or in vitro and activated or to enucleated zygotes. |
| FILED | Thursday, July 31, 2003 |
| APPL NO | 10/632118 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07371385 | Offner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The Government of the United States of America DBA, The Department of Veterans Affairs (Portland, Oregon) |
| INVENTOR(S) | Halina Offner (Portland, Oregon) |
| ABSTRACT | The invention provides a method of ameliorating a Th1-mediated immune pathology in a mammal. The method is practiced by administering a low dose of estrogen to the mammal. Optionally, an immunotherapeutic agent can also be administered to the mammal. Also provided are kits containing a low dose of estrogen and an immunotherapeutic agent. |
| FILED | Friday, May 11, 2001 |
| APPL NO | 10/275833 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07373199 | Sackellares et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Arizona Board of Regents (Tempe, Arkansas) |
| INVENTOR(S) | James Chris Sackellares (Gainesville, Florida); Leonidas D. Iasemidis (Scottsdale, Arizona); Deng-Shan Shiau (Gainesville, Florida); Linda Dance (Gainesville, Florida) |
| ABSTRACT | Characterizing the behavior of a chaotic, multi-dimensional system is achieved by measuring each of a number of signals associated with the system, and generating therefrom, a spatio-temporal response based on each signal. Chaoticity profiles are then generated for each spatio-temporal response. Over a period of time, a determination is made as to whether a certain level of dynamic entrainment and/or disentrainment exists between the chaoticity profiles associated with one or more critical channel groups of a selected predictor, where a predictor represents a given number of critical channel groups “x”, a given number of channels per group “y”, and a total number of channels N. Characterizing the behavior of the system is based on this determination. |
| FILED | Wednesday, August 27, 2003 |
| APPL NO | 10/648354 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 07371784 | Guillot et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Alliant Techsystems Inc. (Edina, Minnesota) |
| INVENTOR(S) | David G. Guillot (Tremonton, Utah); Albert R. Harvey (Brigham City, Utah) |
| ABSTRACT | A novel and improved EPDM formulation for a solid propellant rocket motor is described wherein hexadiene EPDM monomer components are replaced by alkylidene norbornene components, and, with appropriate adjustment of curing and other additives, functionally required rheological and physical characteristics are achieved with the desired compatibility with any one of a plurality of solid filler materials, e.g., powder silica, carbon fibers or aramid fibers, and with appropriate adhesion and extended storage or shelf-life characteristics. |
| FILED | Tuesday, August 31, 2004 |
| APPL NO | 10/931778 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 523/138 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07371216 | Weyand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Peter G. Weyand (Houston, Texas); Matthew W. Bundle (Houston, Texas) |
| ABSTRACT | The present invention includes a method for assessing the fitness of an individual. In one embodiment, the method comprises providing a physical fitness value of an individual by measuring a first trial of an activity conducted by the individual to provide a first measured component. The method further comprises measuring a second trial of an activity conducted by the individual to provide a second measured component. In addition, the method comprises determining the physical fitness values from the first and second measured components. In some embodiments, the method comprises estimating speed or mechanical power output values for the individual over a desired duration. In other embodiments, the method comprises determining the VO2 max of the individual. |
| FILED | Thursday, January 06, 2005 |
| APPL NO | 11/030674 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07370817 | Tilton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Isothermal Systems Research Inc. (Liberty Lake, Washington) |
| INVENTOR(S) | Charles Tilton (Colton, Washington); Jeff Weiler (Liberty Lake, Washington); Randall Palmer (Kendrick, Idaho); Philip Appel (Liberty Lake, Washington) |
| ABSTRACT | An actuated atomizer is adapted for spray cooling or other applications wherein a well-developed, homogeneous and generally conical spray mist is required. The actuated atomizer includes an outer shell formed by an inner ring; an outer ring; an actuator insert and a cap. A nozzle framework is positioned within the actuator insert. A base of the nozzle framework defines swirl inlets, a swirl chamber and a swirl chamber. A nozzle insert defines a center inlet and feed ports. A spool is positioned within the coil housing, and carries the coil windings having a number of turns calculated to result in a magnetic field of sufficient strength to overcome the bias of the spring. A plunger moves in response to the magnetic field of the windings. A stop prevents the pintle from being withdrawn excessively. A pintle, positioned by the plunger, moves between first and second positions. In the first position, the head of the pintle blocks the discharge passage of the nozzle framework, thereby preventing the atomizer from discharging fluid. In the second position, the pintle is withdrawn from the swirl chamber, allowing the atomizer to release atomized fluid. A spring biases the pintle to block the discharge passage. The strength of the spring is overcome, however, by the magnetic field created by the windings positioned on the spool, which withdraws the plunger into the spool and further compresses the spring. |
| FILED | Thursday, October 24, 2002 |
| APPL NO | 10/281391 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/585.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US D569074 | Irwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Donald E. Irwin (Fredericksburg, Virginia); Karen F. Key (Haymarket, Virginia) |
| ABSTRACT | |
| FILED | Tuesday, March 08, 2005 |
| APPL NO | 29/224764 |
| ART UNIT | 2912 — Design |
| CURRENT CPC | Miscellaneous D99/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07371572 | Schiller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health of Human Services (Washington, District of Columbia) |
| INVENTOR(S) | John T. Schiller (Silver Spring, Maryland); Bryce Chackerian (Chevy Chase, Maryland); Douglas R. Lowy (Bethesda, Maryland) |
| ABSTRACT | The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use of the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia. |
| FILED | Monday, June 14, 2004 |
| APPL NO | 10/867119 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07371844 | Gardella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Thomas J. Gardella (Needham, Massachusetts); Henry M. Kronenberg (Belmont, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Harald Juppner (Cambridge, Massachusetts) |
| ABSTRACT | Parathyroid hormone(PTH) polypeptide derivatives are disclosed, as are pharmaceutical compositions containing said polypeptides, and synthetic and recombinant methods for producing said polypeptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing said polypeptides. Also disclosed are methods for screening candidate compounds of the invention for antagonistic or agonistic effects on parathyroid hormone receptor action. Also disclosed are diagnostic and therapeutic methods of said compounds. |
| FILED | Friday, July 08, 2005 |
| APPL NO | 11/176735 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07372409 | Morton |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Harris Corporation (Melbourne, Florida) |
| INVENTOR(S) | Jacob Morton (Melbourne, Florida) |
| ABSTRACT | Patch antenna (100) for a wireless communications device has a reduced size. The patch antenna is operable on a fundamental frequency f0 and a first harmonic f1 of the fundamental frequency, with substantially co-located peak gain directions on both frequencies. The patch antenna (100) is formed from a conductive ground plane (102) of generally rectangular shape. A first aperture (108) provided in the conductive ground plane member (102) defines a bow-tie shape. Additional elongated apertures (118, 120) are provided for reactive loading. The elongated apertures (118, 120) disrupt the phasing of surface currents within the conductive ground plane member (102) around the periphery of the first aperture (108). |
| FILED | Tuesday, February 21, 2006 |
| APPL NO | 11/358146 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 13, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080513.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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