FedInvent™ Patents
Patent Details for Tuesday, June 17, 2008
This page was updated on Monday, March 27, 2023 at 12:58 AM GMT
Department of Defense (DOD)
US 07387028 | Carver et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
INVENTOR(S) | Reed Carver (Aurora, Ohio); Joseph Snyder (Novelty, Ohio); Frederick J. Lisy (Euclid, Ohio); Troy Prince (Cleveland, Ohio) |
ABSTRACT | The present invention relates, in general, to pressure sensors capable of operating at high temperatures. The present invention further relates to a high temperature pressure sensor with an improved gage factor. The present invention still further provides a pressure sensor with a smaller sized diaphragm, which is capable of reading higher pressures. The present invention also provides a method and sensor for detecting strain using shape memory alloys. |
FILED | Friday, April 21, 2006 |
APPL NO | 11/408694 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/715 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387060 | Sanford |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Matthew J. Sanford (Bel Alton, Maryland) |
ABSTRACT | A projectile defense system uses a rocket exhaust generator to generate a rocket exhaust after an approaching projectile is detected/sensed. The rocket exhaust generator directs the rocket exhaust therefrom in a region that intercepts the trajectory of the approaching projectile. |
FILED | Tuesday, May 17, 2005 |
APPL NO | 11/134595 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/1.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387451 | Goossen et al. |
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ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
INVENTOR(S) | Keith Goossen (Howell, New Jersey); Shridrar Yarlagadda (Newark, Delaware); Eric Wetzel (Baltimore, Maryland); Daniel O'Brien (Forest Hill, Maryland) |
ABSTRACT | An apparatus and process for operating connectorless, free-space data porting optical structural composites with integrated optical or electrical busses are disclosed. Optical transceivers and fiber optic/coaxial cable are embedded into a foam-core composite sandwich structure which is infiltrated with vinyl ester resin. The embedded busses are composed of a signal source producing an optical free space signal, which is shone onto an optical/electrical bus containing a transceiver for converting this signal into another electrical or optical signal which then is imprinted upon a coaxial or fiber optic cable buried in the composite structure. The signal traverses the composite structure, then a transceiver converts the electrical/optical signal into a free space optical signal which shines out of the composite structure to an outside free space optical receiver. The optical free space signal is oriented to be received and transmitted at an angle of about 90 degrees relative to the composite material. |
FILED | Thursday, October 12, 2006 |
APPL NO | 11/546931 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/88 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387680 | Tsvetkov et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
INVENTOR(S) | Valeri F. Tsvetkov (Durham, North Carolina); David P. Malta (Raleigh, North Carolina) |
ABSTRACT | A method and apparatus for growing silicon carbide crystals is provided. The apparatus includes a sublimation chamber with a plurality of spaced apart dividers that can direct the direction of silicon carbide crystal growth into passages between the dividers to form a plurality of silicon carbide crystal plates. The silicon carbide crystal plates can be used as seed crystals in subsequent sublimation steps in a manner that promotes the growth of silicon carbide crystals in different crystallographic directions to thereby terminate defect formation. |
FILED | Friday, May 13, 2005 |
APPL NO | 11/128447 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/213 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388088 | Marks et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | James D. Marks (Kensington, California); Robert Schier (San Francisco, California) |
ABSTRACT | This invention provides for novel human antibodies that specifically bind to c-erbB-2. The antibodies may be used alone or as components of chimeric molecules that specifically target and deliver effector molecules to cells overexpressing c-erbB-2. |
FILED | Tuesday, March 05, 2002 |
APPL NO | 10/092640 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.530 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388145 | Olson et al. |
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ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Stanley J. Olson (Newport, Rhode Island); Stephen F. Oliver (Portsmouth, Rhode Island); Robert F. Doleski (Middletown, Rhode Island) |
ABSTRACT | A tailcone assembly for an undersea vehicle includes a first tailcone portion having a cavity and a second tailcone portion positionable in and axially extensible from the cavity. An extensible drive shaft is provided for joining the vehicle's engine to a propeller. The extensible drive shaft includes a first drive shaft joined to the engine, and a second drive shaft rotating with the first drive shaft. The second drive shaft is supported by the second tailcone portion and is axially extensible from the first drive shaft upon deployment of the second portion. The propeller is positioned on the second drive shaft outside the second portion. A biasing means is provided between the tailcone portions for deploying the second portion. |
FILED | Monday, April 04, 2005 |
APPL NO | 11/099778 |
ART UNIT | 3617 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Ships 114/20.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388206 | Ivan |
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ASSIGNEE(S) | GE Homeland Protection, Inc. (Newark, California) |
INVENTOR(S) | Adrian Ivan (Niskayuna, New York) |
ABSTRACT | A method and apparatus for discriminating the types of radiation interacting with an integrated radiation detector having of a pulse-mode operating photosensor which is optically coupled to a gamma-ray scintillator sensor and a neutron scintillator sensor and uses an analog to digital converter (ADC) and a charge to digital converter (QDC) to determine scintillation decay times and classify radiation interactions by radiation type. The pulse processing provides for, among other things, faithful representation of the true energy spectrum of the gamma radiation field and allows for radioisotope identification by searching for the presence of characteristic energy lines in the gamma energy spectrum. The pulse shape discrimination method ensures that the high sensitivity and resolution of the isotope identification function is not affected during operation in mixed neutron-gamma fields. |
FILED | Friday, June 16, 2006 |
APPL NO | 11/424559 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/363.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388235 | Boos et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | John Bradley Boos (Springfield, Virginia); Brian R Bennett (Arlington, Virginia); Richard Magno (Waldorf, Maryland); Nicholas A Papanicolou (Potomac, Maryland); Brad P. Tinkham (Berlin, Germany) |
ABSTRACT | This invention pertains to an electronic device containing a semi-insulating substrate, a buffer layer of an antimony-based material disposed on said substrate, a channel layer of InAsySb1-y material disposed on said buffer layer, a barrier layer of an antimony-based disposed on said channel layer, and a cap layer of InAsySb1-y material disposed on said barrier layer, wherein the device can have frequency of on the order of 500 GHz and a reduced power dissipation. |
FILED | Tuesday, September 20, 2005 |
APPL NO | 11/239431 |
ART UNIT | 2815 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/194 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388247 | Lagnado et al. |
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ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Isaac Lagnado (San Diego, California); Paul R. de la Houssaye (San Diego, California) |
ABSTRACT | A high precision microelectromechanical capacitor with programmable voltage source includes a monolithic MEMS device having a capacitance actuator, a trim capacitor, and a high precision, programmable voltage source. The trim capacitor has a variable capacitance value, preferably for making fine adjustments in capacitance. The capacitance actuator is preferably mechanically coupled to and electrically isolated from the trim capacitor and is used to control the capacitance value of the trim capacitor. The capacitance adjustment of the trim capacitor is non-destructive and may be repeated indefinitely. The trim capacitor may be adjusted by mechanically changing the distance between its electrodes. The programmable voltage source provides a highly accurate and stable output voltage potential corresponding to control signals for controlling the capacitance actuator. The programmable voltage source may optionally include a floating-gate transistor coupled to an amplifier for storing charge and therefore, providing a non-volatile, stable, and adjustable output voltage potential. |
FILED | Wednesday, May 28, 2003 |
APPL NO | 10/446615 |
ART UNIT | 2815 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/312 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388399 | Kursun et al. |
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ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Volkan Kursun (Rochester, New York); Eby G. Friedman (Rochester, New York) |
ABSTRACT | A variable threshold voltage keeper circuit technique is proposed for simultaneous power reduction and speed enhancement of domino logic circuits. The threshold voltage of the keeper transistor is dynamically modified during circuit operation to reduce the contention current without sacrificing noise immunity. The threshold voltage of the keeper transistor is controlled by a body bias generator which switches between two voltages in accordance with the clock signal. |
FILED | Friday, February 17, 2006 |
APPL NO | 11/355950 |
ART UNIT | 2819 — Semiconductors/Memory |
CURRENT CPC | Electronic digital logic circuitry 326/33 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388486 | Dalzell et al. |
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ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | William J. Dalzell (Parrish, Florida); Scott G. Fleischman (Palmetto, Florida); James L. Tucker (Clearwater, Florida) |
ABSTRACT | An optical anti-tamper system that includes at least one array of light sources located within a chassis and at least one array of photosensitive elements located within the chassis. The array of photosensitive elements are in communication with an alarm. The alarm is operable to transmit a tamper-event warning signal if an increased light level is detected by at least one array of photosensitive elements. |
FILED | Thursday, January 05, 2006 |
APPL NO | 11/325732 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/555 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388497 | Corbett et al. |
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ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Blaise L. Corbett (King George, Virginia); Michael L. Woodman (Ruther Glen, Virginia) |
ABSTRACT | Radio frequency identification (RFID) includes far-field systems associated with an RFID interrogator and an RFID tag. The RFID interrogator produces continuous wave (CW) unmodulated signals selected from frequencies comprising a predetermined frequency band. The RFID tag includes reception and transmission antenna circuits, a signal processor, and an oscillator. The reception antenna circuit receives the reception signals from the RFID interrogator. The signal processor determines whether the reception signals correspond to a plurality of tag identification frequencies as a correlation. The signal processor also produces responsive signals in response to the correlation. The oscillator supplies a carrier frequency. The transmission antenna circuit combines the carrier signal with the response signals to produce transmit signals, and then dispatches the transmit signals. |
FILED | Wednesday, February 01, 2006 |
APPL NO | 11/363296 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/572.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388538 | Thompson, III |
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ASSIGNEE(S) | Th United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Andrew A. Thompson, III (North East, Maryland) |
ABSTRACT | A system and method of determining an orientation of a spinning object at a known GPS location comprises radially deploying antennae around a plurality of axes of measurement of the spinning object; determining a spin axis of a first end of the spinning object; measuring, using a frequency domain correlation, a roll angle corresponding to the spin axis in relation to a first plane of the GPS location; repeating the measuring process for multiple planes of the GPS location; and generating the orientation of the spinning object by combining all roll angle measurements. The method further comprises determining a sensing vector orthogonal to the spin axis; identifying at least two known GPS locations corresponding to the spinning object; and rotating the sensing vector about the spin axis until two of the known GPS locations become visible or are in the plane of the sensing vector and the spin axis. |
FILED | Friday, August 18, 2006 |
APPL NO | 11/507201 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/357.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07389053 | Ilchenko et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | OEwaves, Inc. (Pasadena, California) |
INVENTOR(S) | Vladimir Ilchenko (Arcadia, California); Lutfollah Maleki (Pasadena, California) |
ABSTRACT | Devices and techniques for achieving signal filtering in RF or microwave frequencies by optical filtering using two separate optical paths. Each optical path may include one or more optical resonators to achieve desired optical filtering. |
FILED | Wednesday, January 12, 2005 |
APPL NO | 11/035020 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Optical communications 398/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07389162 | Altieri et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Lord Corporation (Cary, North Carolina) |
INVENTOR(S) | Russell E. Altieri (Cary, North Carolina); James F. Kuhn (Erie, Pennsylvania); Mark R. Jolly (Raleigh, North Carolina); Steve C. Southward (Apex, North Carolina); Askari Badre-Alam (Apex, North Carolina); Leslie P. Fowler (Cary, North Carolina) |
ABSTRACT | Methods and systems for monitoring rotating shaft shafts and couplings in an aircraft propulsion system is described. The measurement system/method provides for accurate and precise monitoring of a rotating shaft flexible coupling in a fixed wing aircraft vehicle propulsion system. The measuring system/method provides for a high reliability short take off vertical landing fixed wing aircraft in which the vertical propulsion dynamically rotating drive shaft system and couplings are monitored in real time. The vehicular shaft coupling misalignment measuring system utilizes multiple positional sensors to provide highly reliable and precise determination of the dynamic characteristics of the rotating sensor target components of the propulsion system drive shaft. The relative position of the sensors is rigidly fixed externally from the rotating targets with a structural frame. The collar misalignment measuring system of the invention provide a misalignment measurement of the propulsion system drive shaft flexible coupling which relates to a critical performance of rotating shaft coupling in the operation of an aircraft vehicle. The method/system provides for monitoring a rotating drive shaft system and dynamically measuring a rotating drive shaft coupling in a fixed wing aircraft propulsion system. |
FILED | Monday, September 12, 2005 |
APPL NO | 11/224563 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07389192 | Cranford, Jr. et al. |
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ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Hayden C. Cranford, Jr. (Cary, North Carolina); Fadi H. Gebara (Austin, Texas); Jeremy D. Schaub (Austin, Texas) |
ABSTRACT | A method for determining data signal jitter via asynchronous sampling provides a low cost and production-integrable mechanism for measuring data signal jitter. The data signal is edge-detected and sampled by a sampling clock of unrelated frequency the sampled values are collected in a histogram according to a folding of the samples around a timebase. The timebase is determined by sweeping to detect a minimum jitter for the folded data. The histogram for the correct estimated timebase period is representative of the probability density function of the location of data signal edges and the jitter characteristics are determined by the width and shape of the density function peaks. Frequency drift can be corrected by adjusting the timebase used to fold the data across the sample set. |
FILED | Friday, June 30, 2006 |
APPL NO | 11/427940 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/69 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07389233 | Gish et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Verizon Corporate Services Group Inc. (Basking Ridge, New Jersey); BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | Herbert Gish (Newton, Massachusetts); William R. Belfield (Boylston, Massachusetts) |
ABSTRACT | A system is provided that trains a speech processing device to recognize any spoken language. The speech processing device is trained by receiving a group of speech frames (302). The group of speech frames is grouped into a group of segments (304). A model of each of the segments is created (306) and the segments are compared (308). The segments are grouped into clusters based on comparisons of the segments (310). A model for each of the clusters is built (312). The built cluster models enable the labeling of segments from speech in the language. Labeled segments (i.e., recognizer output) may be used to train topic classifiers. Speech topics may be classified on the basis of the generated labeled segments. |
FILED | Friday, August 20, 2004 |
APPL NO | 10/922721 |
ART UNIT | 2626 — Selective Visual Display Systems |
CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/270 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 07387327 | Tencer et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Allan Tencer (Seattle, Washington); Robert Philip Kaufman (Seattle, Washington); Charles Newman Mock (Seattle, Washington) |
ABSTRACT | A system for managing an occupant in an occupant compartment of an automotive vehicle, a structure for use in an automobile, and methods of use thereof are provided for protecting an occupant during a near side impact collision. |
FILED | Friday, June 24, 2005 |
APPL NO | 11/165945 |
ART UNIT | 3612 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Land vehicles: Bodies and tops 296/68.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387777 | Wagner et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Center For Blood Research, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Denisa D. Wagner (Wellesley, Massachusetts); Patrick Andre (Jamaica Plain, Massachusetts); Daqing W. Hartwell (Brookline, Massachusetts); Ingrid Hrachovinova (Jamaica Plain, Massachusetts) |
ABSTRACT | The present invention identifies P-selectin as a modulator of hemostasis. Accordingly, the present invention relates to methods for the identification and use of modulators of P-selectin activity as modulators of hemostasis. The invention also relates to methods and compositions for the diagnosis and treatment of hemostatic disorders, including, but not limited to, hemorrhagic disorders and thrombotic disorders. The present invention describes methods for the diagnostic evaluation and prognosis of various hemostatic conditions, and for the identification of subjects exhibiting a predisposition to such conditions. In addition, the present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of a hemostatic or vascular disorders, and for monitoring the efficacy of compounds in clinical trials. |
FILED | Thursday, February 19, 2004 |
APPL NO | 10/782456 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/134.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387779 | Kalluri |
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APPLICANT(S) | |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
INVENTOR(S) | Raghuram Kalluri (Boston, Massachusetts) |
ABSTRACT | Proteins with anti-angiogenic properties are disclosed, and fragments thereof, and methods of using those proteins and fragments to inhibit or promote angiogenesis. |
FILED | Friday, December 21, 2001 |
APPL NO | 10/032221 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387782 | Zaia et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | John A. Zaia (Arcadia, California); Ghislaine Hawkins (Glendora, California) |
ABSTRACT | This invention relates to mutated CMVpp65, a viral structural protein which activates cell mediated immunity in humans infected with CMV. The mutations remove undesirable protein kinase activity naturally present in the protein and make it suitable for the production of both DNA and protein vaccines. Therefore, the invention provides proteins and DNAS, as well as vaccines comprising the proteins and DNAs, including cellular vaccines and vectors. Other embodiments of the invention relate to methods of enhancing immune response and vaccinating against CMV, including gene therapy methods and vectors. |
FILED | Thursday, August 18, 2005 |
APPL NO | 11/206162 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/230.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387881 | Hanash et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Samir M. Hanash (Ann Arbor, Michigan); Laura Beretta (Ann Arbor, Michigan); Francois LeNaour (Villejuif, France) |
ABSTRACT | The present invention relates to compositions and methods for cancer therapies and diagnostics, including but not limited to, cancer markers. In particular, the present invention provides tumor antigens associated with specific cancers and diagnostic assays for the detection of such antigens and associated autoantibodies as indicative of the presence of specific cancers. The present invention further provides cancer immunotherapy utilizing the tumor antigens of the present invention. |
FILED | Monday, September 16, 2002 |
APPL NO | 10/244854 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387896 | Turner et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | David Loyd Turner (Ann Arbor, Michigan); Kwan-Ho Chung (Ann Arbor, Michigan); Paresh D. Patel (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to gene silencing, and in particular to compositions of microRNA sequences and vectors and to methods of synthesizing such in vitro and in vivo, and to methods of using such to regulate gene expression. |
FILED | Tuesday, June 21, 2005 |
APPL NO | 11/158201 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387997 | McIntosh |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah (Salt Lake City, Utah) |
INVENTOR(S) | J. Michael McIntosh (Salt Lake City, Utah) |
ABSTRACT | The invention relates to novel conopeptides and/or novel Luses of conopeptides. The conopeptides of the invention are analogs of α-Conotoxin MII that are selective for α6-containing nAChRs as described herein. |
FILED | Wednesday, November 09, 2005 |
APPL NO | 11/269879 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388070 | Coen et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Donald Coen (Medfield, Massachusetts); James Hogle (Newton, Massachusetts); Carl Elkin (Cambridge, Massachusetts); Harmon J. Zuccola (Brookline, Massachusetts); Kristie Grove Bridges (Maynard, Massachusetts); Scott Lokey (Santa Cruz, California) |
ABSTRACT | A method for the structure-based identification and selection of inhibitors of processivity factor binding to protein is disclosed herein. Characterization of the protein/processivity factor interface is given. Methods for the structure-based inhibition of processivity factor binding to protein are also given. One embodiment includes a class of peptidomimetics that mimic helical portions of proteins. In addition, methods of treatment of various diseases are given, using the inhibitors of the invention. |
FILED | Friday, May 12, 2000 |
APPL NO | 09/959948 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/232 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388074 | Lawrence et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Daniel A. Lawrence (Derwood, Maryland); Steingrimor P. Stefansson (Gaithersburg, Maryland) |
ABSTRACT | Mutants of the human PAI-1 protein are described which are inhibitors of neutrophil elastase or are inhibitors of vitronectin (Vn)-dependent cell migration. These mutants preferably comprise one or two amino acid substitutions in the reactive center loop of PAI-1, particularly at positions 331 and 346 of the mature protein. These mutants are notable in being resistant to inactivation by elastase, having high affinity for Vn, or both properties. These mutant proteins as pharmaceutical compositions are used to inhibit elastase in a subject, thereby treating a number of disorders associated with elastase activity, most notatably emphysema, ARDS, inflammatory lung injury and cystic fibrosis. The mutants which interact with Vn are used to inhibit cell migration in a subject, thereby treating diseases or conditions associated with undesired cell migration and proliferation, particularly of smooth muscle cells. Such conditions include atherosclerosis, post angioplasty restenosis, fibrosis associated with chronic inflammation or chemotherapy, tumor invasion and metastasis and conditions in which angiogenesis is pathogenic. Also disclosed are peptides of such mutant proteins, mutant-specific antibodies, nucleic acid molecules, particularly DNA, encoding the mutant protein and host cells transformed by such nucleic acids. |
FILED | Monday, September 30, 2002 |
APPL NO | 10/259609 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388076 | Sanberg et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Paul R. Sanberg (Spring Hill, Florida); Robert W. Engelman (Tampa, Florida); William R. Gower (Seffner, Florida) |
ABSTRACT | A method for purifying an immunosuppressant protein (HISP) has the steps of obtaining supernatant from hNT cells; exposing the supernatant to preparative polyacrylamide gel electrophoresis to produce 20 isoelectric fractions, including active isoelectric fraction #10; placing the active isoelectric fraction on a Blue Sepharose column to bind albumin; and collecting the free fraction containing the concentrated, isolated HISP. Also disclosed is a method of treating inflammation, using an effective amount of an HISP. The HISP is anionic, has a molecular weight of 40-100 kDa, an isoelectric point of about 4.8 and is obtained from the supernatant of hNT cells, but not from NCCIT embryonal carcinoma cells, T98G glioblastoma cells or THP-1 monocytic leukemia cells. HISP can maintain T cells in a quiescent G0/G1 state without lowering their viability. HISP loses activity when treated with heat, pH2, pH11, or mixed with trypsin or carboxypeptidase, but not with neuraminidase. HISP can suppress proliferation of responder peripheral blood mononuclear cells in allogeneic mixed lymphocyte cultures; HISP can suppress T-cell proliferation and IL-2 production in response to phorbol 12-myristate 13-acetate (PMA), ionomycin and concanavalin-A. HISP does not bind to heparin-sepharose CL-B gel; or to albumin-binding resin Blue Sepharose. HISP is concentrated with YM10 ultrafiltration. HISP does not act through the T-cell receptor-CD3 complex or via altered accessory signal cells. A method of treating inflammation comprises administering an effective amount of hNT neuronal cells. |
FILED | Wednesday, July 16, 2003 |
APPL NO | 10/621061 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388080 | Kurt-Jones et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Evelyn A. Kurt-Jones (Belmont, Massachusetts); Robert W. Finberg (Sudbury, Massachusetts) |
ABSTRACT | It has been found that Toll-like receptor 1 and Toll-like receptor 2 (TLR2) physically interact. Antibodies that specifically bind to TLR2 and selectively inhibit induction of cytokines are also described. The invention relates to specific antibodies that selectively bind to TLR2, and to methods of identifying compounds that selectively interfere with signaling through TLR1/TLR2 complexes. |
FILED | Friday, August 20, 2004 |
APPL NO | 10/923280 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388088 | Marks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | James D. Marks (Kensington, California); Robert Schier (San Francisco, California) |
ABSTRACT | This invention provides for novel human antibodies that specifically bind to c-erbB-2. The antibodies may be used alone or as components of chimeric molecules that specifically target and deliver effector molecules to cells overexpressing c-erbB-2. |
FILED | Tuesday, March 05, 2002 |
APPL NO | 10/092640 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.530 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388089 | Valenzuela et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Jesus G. Valenzuela (Rockville, Maryland); Yasmine Belkaid (Norwood, Ohio); Shaden Kamhawi (Rockville, Maryland); David Sacks (Silver Spring, Maryland); Jose M. C. Ribeiro (Rockville, Maryland) |
ABSTRACT | The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis. |
FILED | Tuesday, June 18, 2002 |
APPL NO | 10/481180 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388093 | Slaugenhaupt et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Susan Slaugenhaupt (Quincy, Massachusetts); James F. Gusella (Framingham, Massachusetts) |
ABSTRACT | This invention relates to methods and compositions useful for detecting mutations which cause Familial Dysautonomia. Familial dysautonomia (FD; Riley-Day syndrome), an Ashkenazi Jewish disorder, is the best known and most frequent of a group of congenital sensory neuropathies and is characterized by widespread sensory and variable autonomic dysfunction. Previously, we mapped the FD gene, DYS, to a 0.5 cM region of chromosome 9q31 and showed that the ethnic bias is due to a founder effect, with >99.5% of disease alleles sharing a common ancestral haplotype. To investigate the molecular basis of FD, we sequenced the minimal candidate region and cloned and characterized its 5 genes. One of these, IKBKAP, harbors two mutations that can cause FD. The major haplotype mutation is located in the donor splice site of intron 20. This mutation can result in skipping of exon 20 in the mRNA from FD patients, although they continue to express varying levels of wild-type message in a tissue-specific manner. RNA isolated from patient lymphoblasts is primarily wild-type, whereas only the deleted message is seen in RNA isolated from brain. The mutation associated with the minor haplotype in four patients is a missense (R696P) mutation in exon 19 that is predicted to disrupt a potential phosphorylation site. Our findings indicate that almost all cases of FD are caused by an unusual splice defect that displays tissue-specific expression; and they also provide the basis for rapid carrier screening in the Ashkenazi Jewish population. |
FILED | Monday, January 07, 2002 |
APPL NO | 10/041856 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/24.310 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388207 | Zeng |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Gengsheng Lawrence Zeng (Salt Lake City, Utah) |
ABSTRACT | A skew slit collimator for a gamma ray imaging device and a method of configuring the skew slit collimator for a gamma ray imaging device is disclosed. The gamma ray imaging device includes a detector having a generally planar detector surface. The detector surface is operable to be positioned adjacent a subject imaging region. The skew slit collimator includes a first collimator blade having a first slit and a second collimator blade having a second slit. The first collimator blade is disposed in front of and generally parallel to the detector surface. The second collimator blade is disposed between the first collimator blade and the detector surface. The second collimator is generally parallel to and spaced apart from the first collimator blade. The second collimator blade is oriented with respect to the first collimator blade such that the lengthwise orientation of the second slit is generally orthogonal to a lengthwise orientation of the first slit. |
FILED | Tuesday, March 28, 2006 |
APPL NO | 11/391599 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/363.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388288 | Solzbacher et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah); Fraunhofer-Gesellschaft zur Foerderung der angewan (Munich, Germany) |
INVENTOR(S) | Florian Solzbacher (Salt Lake City, Utah); Reid Harrison (Salt Lake City, Utah); Richard A. Normann (Park City, Utah); Hans-Hermann Oppermann (Berlin, Germany); Lothar Dietrich (Werder (Havel), Germany); Matthias Klein (Berlin, Germany); Michael Töpper (Berlin, Germany) |
ABSTRACT | Interconnect metallization schemes and devices for flip chip bonding are disclosed and described. Metallization schemes include an adhesion layer, a diffusion barrier layer, a wetable layer, and a wetting stop layer. Various thicknesses and materials for use in the different layers are disclosed and are particularly useful for metallization in implantable electronic devices such as neural electrode arrays. |
FILED | Friday, December 01, 2006 |
APPL NO | 11/607273 |
ART UNIT | 2823 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/738 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388668 | Potma et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Eric O. Potma (Cambridge, Massachusetts); Conor Evans (Cambridge, Massachusetts); Xiaoliang Sunney Xie (Lexington, Massachusetts) |
ABSTRACT | A system is disclosed for detecting a non-linear coherent field induced in a sample volume. The system includes a first source for generating a first electromagnetic field at a first frequency, a second source for generating a second electromagnetic field at a second frequency, first optics for directing the first and second electromagnetic fields toward the sample volume, second optics for directing the first and second electromagnetic fields toward a local oscillator volume, and an interferometer. The interferometer is for interfering a first scattering field that is generated by the interaction of the first and second electromagnetic fields in the sample volume, with a second scattering field that is generated by the interaction of the first and second electromagnetic fields in the local oscillator volume. |
FILED | Friday, June 03, 2005 |
APPL NO | 11/145420 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/451 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07387027 | Choi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Jaime D. Choi (Somerville, Massachusetts); Benjamin Paxton (Cambridge, Massachusetts); Thomas Feurer (Bern, Switzerland); Masashi Yamaguchi (Green Island, New York); Keith A. Nelson (Newton, Massachusetts) |
ABSTRACT | A method for characterizing one or more properties of a sample using acoustic waveforms is disclosed, and comprises directing a sequence of at least three optical pulses to the sample to generate an acoustic response in the sample at a frequency corresponding to the pulse sequence, varying the timing of one or more of the pulses in the sequence to vary the frequency of the acoustic response in the sample, and measuring the strength of the acoustic response as a function of the varied frequency to determine information about the sample. |
FILED | Thursday, July 21, 2005 |
APPL NO | 11/186401 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/668 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387197 | Sprouse et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Pratt and Whitney Rocketdyne, Inc. (Canoga Park, California) |
INVENTOR(S) | Kenneth M. Sprouse (Northridge, California); David R. Matthews (Simi Valley, California) |
ABSTRACT | A pump for transporting particulate material includes an inlet, an outlet, a passageway, a first and second load beam, a first and second scraper seal, and a first and second drive assembly. The inlet introduces the particulate material into the passageway and the outlet expels the particulate material from the passageway. The passageway is defined by a first belt assembly and a second belt assembly that are opposed to each other. The first and second load beams are positioned within the first belt assembly and the second belt assembly, respectively. The first scraper seal and a second scraper seal are positioned proximate the passageway and the outlet. The first drive assembly is positioned within an interior section of the first belt assembly and drives the first belt assembly and the second drive assembly is positioned within an interior section of the second belt assembly and drives the second belt assembly. |
FILED | Wednesday, September 13, 2006 |
APPL NO | 11/520154 |
ART UNIT | 3651 — Material and Article Handling |
CURRENT CPC | Conveyors: Power-driven 198/626.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387757 | Mulligan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Advanced Ceramics Research, Inc. (Tucson, Arizona) |
INVENTOR(S) | Anthony C. Mulligan (Tucson, Arizona); Mark J. Rigali (Carlsbad, New Mexico); Manish P. Sutaria (Malden, Massachusetts); Gregory J. Artz (Tucson, Arizona); Felix H. Gafner (Tucson, Arizona); K. Ranji Vaidyanathan (Tucson, Arizona) |
ABSTRACT | Processes for mechanically fabricating two and three-dimensional fibrous monolith composites include preparing a fibrous monolith filament from a core composition of a first powder material and a boundary material of a second powder material. The filament includes a first portion of the core composition surrounded by a second portion of the boundary composition. One or more filaments are extruded through a mechanically-controlled deposition nozzle onto a working surface to create a fibrous monolith composite object. The objects may be formed directly from computer models and have complex geometries. |
FILED | Tuesday, June 29, 2004 |
APPL NO | 10/880189 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/241 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387875 | Berka et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
INVENTOR(S) | Randy Berka (Davis, California); Elena Bachkirova (Davis, California); Michael Rey (Davis, California) |
ABSTRACT | The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing Trichoderma reesei ESTs or SSH clones, or a combination thereof. The present invention also relates to computer readable media and substrates containing such array features for monitoring expression of a plurality of genes in filamentous fungal cells. |
FILED | Friday, September 24, 2004 |
APPL NO | 10/950009 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387876 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kun Zhang (Brighton, Massachusetts) |
ABSTRACT | Methods of reducing background during amplification of small amounts of nucleic acids employ careful analysis of sources of low level contamination. Ultraviolet light can be used to reduce nucleic acid contaminants in reagents and equipment. “Primer-dimer” background can be reduced by judicious design of primers. We have shown clean signal-to-noise with as little as starting material as one single human cell (˜6 picogram), E. coli cell (˜5 femtogram) or Prochlorococcus cell (˜3 femtogram). |
FILED | Monday, February 28, 2005 |
APPL NO | 11/066559 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388896 | Roach et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Jay A. Roach (Idaho Falls, Idaho); John G. Richardson (Idaho Falls, Idaho); Brian D. Raivo (Idaho Falls, Idaho); Nicholas R. Soelberg (Idaho Falls, Idaho) |
ABSTRACT | Apparatus and methods of operation are provided for a cold-crucible-induction melter for vitrifying waste wherein a single induction power supply may be used to effect a selected thermal distribution by independently energizing at least two inductors. Also, a bottom drain assembly may be heated by an inductor and may include an electrically resistive heater. The bottom drain assembly may be cooled to solidify molten material passing therethrough to prevent discharge of molten material therefrom. Configurations are provided wherein the induction flux skin depth substantially corresponds with the central longitudinal axis of the crucible. Further, the drain tube may be positioned within the induction flux skin depth in relation to material within the crucible or may be substantially aligned with a direction of flow of molten material within the crucible. An improved head design including four shells forming thermal radiation shields and at least two gas-cooled plenums is also disclosed. |
FILED | Monday, October 17, 2005 |
APPL NO | 11/253138 |
ART UNIT | 3742 — Optics |
CURRENT CPC | Industrial electric heating furnaces 373/151 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07387027 | Choi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Jaime D. Choi (Somerville, Massachusetts); Benjamin Paxton (Cambridge, Massachusetts); Thomas Feurer (Bern, Switzerland); Masashi Yamaguchi (Green Island, New York); Keith A. Nelson (Newton, Massachusetts) |
ABSTRACT | A method for characterizing one or more properties of a sample using acoustic waveforms is disclosed, and comprises directing a sequence of at least three optical pulses to the sample to generate an acoustic response in the sample at a frequency corresponding to the pulse sequence, varying the timing of one or more of the pulses in the sequence to vary the frequency of the acoustic response in the sample, and measuring the strength of the acoustic response as a function of the varied frequency to determine information about the sample. |
FILED | Thursday, July 21, 2005 |
APPL NO | 11/186401 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/668 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387846 | Redepenning |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Jody G. Redepenning (Lincoln, Nebraska) |
ABSTRACT | An article coated with an electrolytically deposited bio-compatible composite layer useful as an internal prosthetic device is disclosed. The bio-compatible composite coating that is electrolytically deposited onto the article comprises hydroxyapatite and chitosan. The introduction of chitosan into the crystal matrix of brushite/hydroxyapatite significantly improves the adhesive and chemical and mechanical stability properties of the coating. |
FILED | Friday, October 21, 2005 |
APPL NO | 11/254710 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/698 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07387888 | Strobel et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Montana State University (Bozeman, Montana); Novozymes Biotech Inc. (Davis, California) |
INVENTOR(S) | Gary A. Strobel (Bozeman, Montana); Debbie S. Yaver (Davis, California); Uvidelio F. Castillo (Bozeman, Montana); David Ezra (Adanim, Israel) |
ABSTRACT | The present invention relates to isolated strains of a Streptomyces spp. which are endophytes of dicotyledonous plants and to methods for selecting such strains. The present invention also relates to a biologically active compound called coronamycin obtained from endophytic Streptomycetes isolated from higher plants. The present invention further relates to compositions of such compounds and to methods of protecting plants against attack by a plant pathogen and methods of inhibiting bacterial growth, fungal growth, viral infection, growth of parasitic organisms, and cancer cell growth with such compositions. |
FILED | Thursday, February 24, 2005 |
APPL NO | 11/064486 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/93 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07387147 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Ebert Composites Corporation (Chula Vista, California) |
INVENTOR(S) | David W. Johnson (San Diego, California); Scott A. Garrett (San Diego, California); James M. Hooks (Alpine, California); Stephen G. Moyers (Jamul, California) |
ABSTRACT | A method of inserting z-axis reinforcing fibers into a multi-layer composite laminate. Layers of material made up of z-axis fiber and y-axis fibers are automatically transported into a z-fiber deposition machine having a housing with upper and lower surfaces. Z-axis apertures are formed in the respective upper and lower surfaces. An elongated solid rod having a tapered front tip is aligned in close proximity to the aperture in the bottom surface. The rod is first rotated by a motor and then actuated upwardly completely through the thickness of the layer of x-y material by an actuator. A first hollow tube having a z-axis is axially aligned with the aperture in the top surface and a fiber bundle is threaded downwardly through a first hollow tube to a position adjacent its bottom end. The z-fiber deposition machine has structure to feed a predetermined length of the fiber bundle downwardly through the first hollow tube so that it follows the pathway in the x-y material formed by the rod which is now withdrawn downwardly through the aperture in the bottom wall. The z-axis fiber is thus deposited into the x-y material. The top end of the z-axis fiber is then severed and the x-y material is then advanced a predetermined distance to complete the cycle and is, thus, set to be repeated. |
FILED | Monday, September 11, 2006 |
APPL NO | 11/530859 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/433 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07388084 | Wilson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cognis Corporation (Ambler, Pennsylvania) |
INVENTOR(S) | C. Ron Wilson (Loveland, Ohio); David L. Craft (Ft. Thomas, Kentucky); Yeyan Zhang (Mason, Ohio); Jeffrey B. Stavenhagen (Brookeville, Maryland) |
ABSTRACT | The present invention provides modified promoters from Candida troplicalis CYP and POX4 genes. The modified promoters have various sequence motifs added, deleted, or altered in order to modulate expression of a coding sequence operably linked thereto. The sequence motifs comprise repressors of gene induction (URS sequences) and activators of gene induction (UAS sequences) as well as oleic acid response elements (ORE sequences). Yeast host cells comprising such modified promoters are also provided. Methods of altering expression of a protein of the beta or omega oxidation pathways using a subject modified promoter are also provided. |
FILED | Thursday, August 14, 2003 |
APPL NO | 10/640962 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07387205 | Wilson |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Charles I. Wilson (Shepherdstown, West Virginia) |
ABSTRACT | A packaging system for preserving perishable items which involves a thermoplastic reclosable bag or container wherein the thermoplastic reclosable bag or container involves sealed means for closing one end of the thermoplastic reclosable bag or container, and an external patch for delivering active packaging materials (e.g., chemicals) into the thermoplastic reclosable bag or container, and means for flowing active packaging materials into the thermoplastic reclosable bag or container from the external patch into the thermoplastic reclosable bag or container. Such packaging can perform a number of functions such as moisture regulation, antimicrobial emission, ethylene scavenging, ethylene emission, antioxidant emission, flavor adsorption and emission, and oxygen and carbon dioxide regulation. The present invention allows the segregation of active compounds in plastic packaging within an external patch that prevents the direct contact of such compounds and the contents of the package but allows the free exchange of liquids and/or gasses between the patch contents and the package interior. |
FILED | Thursday, November 10, 2005 |
APPL NO | 11/271695 |
ART UNIT | 3728 — Material and Article Handling |
CURRENT CPC | Special receptacle or package 26/524.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 07388206 | Ivan |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | GE Homeland Protection, Inc. (Newark, California) |
INVENTOR(S) | Adrian Ivan (Niskayuna, New York) |
ABSTRACT | A method and apparatus for discriminating the types of radiation interacting with an integrated radiation detector having of a pulse-mode operating photosensor which is optically coupled to a gamma-ray scintillator sensor and a neutron scintillator sensor and uses an analog to digital converter (ADC) and a charge to digital converter (QDC) to determine scintillation decay times and classify radiation interactions by radiation type. The pulse processing provides for, among other things, faithful representation of the true energy spectrum of the gamma radiation field and allows for radioisotope identification by searching for the presence of characteristic energy lines in the gamma energy spectrum. The pulse shape discrimination method ensures that the high sensitivity and resolution of the isotope identification function is not affected during operation in mixed neutron-gamma fields. |
FILED | Friday, June 16, 2006 |
APPL NO | 11/424559 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/363.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
US 07388947 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Federal Bureau of Investigation, The United States of America as represented by the Office of the General Counsel (Washington, District of Columbia); Lucent Technologies, Inc. (Murray Hill, New Jersey) |
INVENTOR(S) | David B. Smith (Hinsdale, Illinois); Matthew Richard Smith (Hinsdale, Illinois); David L. Yarbrough (Reston, Virginia); Eric Edward Kampmeier (Sycamore, Illinois); Simon S. Oh (Naperville, Illinois); Thomas J. Loos (Lisle, Illinois) |
ABSTRACT | Data generated at a telecommunications network switching node is selectively delivered to one or more data receiving device (e.g., data “collection box”) connected to the network, and command and control signaling is transmitted from the data receiving device to the switching node. This bi-directional communication is carried out in a manner compatible with voice grade lines. In an exemplary application, call identifying information, referred to in the TIA/EIA Standard as CDC (Call Data Channel) Messages, is delivered from an Intercept Access Point (IAP) switch that provides telephone service to a subject of an authorized surveillance order, to a law enforcement data collection box, utilizing Frequency Shift Keying (FSK) signals. Control signals are sent from the data collection box to the IAP switch utilizing Dual Tone Multi-Frequency (DTMF) signaling. The state of the art is advanced, and a contribution is made to law enforcement and other fields, as the invention allows replacement of costly and lengthily provisioned data delivery circuits, such as ISDN lines or private digital data circuits, with widely available and less expensive voice-band data delivery equipment. |
FILED | Friday, March 14, 2003 |
APPL NO | 10/387554 |
ART UNIT | 2614 — Optics |
CURRENT CPC | Telephonic communications 379/35 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 07387327 | Tencer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Allan Tencer (Seattle, Washington); Robert Philip Kaufman (Seattle, Washington); Charles Newman Mock (Seattle, Washington) |
ABSTRACT | A system for managing an occupant in an occupant compartment of an automotive vehicle, a structure for use in an automobile, and methods of use thereof are provided for protecting an occupant during a near side impact collision. |
FILED | Friday, June 24, 2005 |
APPL NO | 11/165945 |
ART UNIT | 3612 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Land vehicles: Bodies and tops 296/68.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 07388381 | Werkema, Jr. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | U.S. Environmental Protection Agency (Washington, District of Columbia) |
INVENTOR(S) | Douglas D. Werkema, Jr. (Las Vegas, Nevada) |
ABSTRACT | A in situ probe for the measurement of the geoelectrical properties of a geological formation. The probe serves as the interface between a standard acquisition system and the earth. The probe is customizable in its length and the type of electrodes used to make contact with the geologic formation. The probe is permanently installed for long term measurements, it contains closely spaced electrodes enabling a high vertical or depth resolution of measurements. The electrode type is customizable either stainless steel or non-polarizing. |
FILED | Monday, April 23, 2007 |
APPL NO | 11/738659 |
ART UNIT | 2862 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/347 |
VIEW PATENT | @ USPTO: Full Text PDF |
General Services Administration (GSA)
US 07387276 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
INVENTOR(S) | James E. Smith (Bruceton Mills, West Virginia); Roy S. Nutter, Jr. (Morgantown, West Virginia); Gregory J. Thompson (Morgantown, West Virginia); Zenovy S. Wowczuk (Morgantown, West Virginia); Gerald M. Angle, II (Morgantown, West Virginia) |
ABSTRACT | A roll-on/roll-off, aircraft-borne sensor pod deployment system having an operator station and a sensor pallet system and method of using same. The operator station has a base platform, a shelter box mounted on the base platform for accommodating a human operator, and a computer installed inside the shelter box. The sensor pallet system has a base platform, a linear system mounted on the base platform, a rotational system mounted on the linear system, a mechanical arm attached to the rotational system, a sensor pod attached to the mechanical arm, and an electrical control system that provides power to the deployment system and controls movements of the sensor pallet system. In operation, the sensor pod can be retracted into a compact, stowing position, or extended out an opening in the aircraft for an unobstructed field of view. The deployment system optionally includes an apparatus and method for sealing the aircraft opening. |
FILED | Wednesday, November 24, 2004 |
APPL NO | 10/996885 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/118.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07387757 | Mulligan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Advanced Ceramics Research, Inc. (Tucson, Arizona) |
INVENTOR(S) | Anthony C. Mulligan (Tucson, Arizona); Mark J. Rigali (Carlsbad, New Mexico); Manish P. Sutaria (Malden, Massachusetts); Gregory J. Artz (Tucson, Arizona); Felix H. Gafner (Tucson, Arizona); K. Ranji Vaidyanathan (Tucson, Arizona) |
ABSTRACT | Processes for mechanically fabricating two and three-dimensional fibrous monolith composites include preparing a fibrous monolith filament from a core composition of a first powder material and a boundary material of a second powder material. The filament includes a first portion of the core composition surrounded by a second portion of the boundary composition. One or more filaments are extruded through a mechanically-controlled deposition nozzle onto a working surface to create a fibrous monolith composite object. The objects may be formed directly from computer models and have complex geometries. |
FILED | Tuesday, June 29, 2004 |
APPL NO | 10/880189 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/241 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07387189 | James et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corp. (Hartford, Connecticut) |
INVENTOR(S) | Denman H. James (Windsor, Connecticut); J. Axel Glahn (Manchester, Connecticut) |
ABSTRACT | An emergency lubrication system for a turbine engine includes a reservoir 50 containing a reserve quantity of lubricant 52 and having a lubricant inlet 54 and a lubricant outlet 56. A lubricant supply line 62 and a lubricant outlet line 66 each have a respective valves 64, 68 for regulating lubricant flow into and out of the reservoir. A fluid supply line 70 includes a valve 72 for selectively establishing communication between the reserve quantity of lubricant and a source of pressurized fluid. During normal operation the lubricant outlet valve continuously releases lubricant at a normal rate to the component requiring lubrication while the lubricant inlet valve concurrently admits fresh lubricant into the reservoir. During abnormal operation, the lubricant inlet valve closes in response to abnormally low lubricant pressure outside the reservoir thereby preventing backflow of reserve lubricant out of the reservoir. The fluid inlet valve opens to admit pressurized fluid into the reservoir thus pressurizing the reserve lubricant. The lubricant outlet valve opens or cycles open and closed in response to a command from a controller 26 so that the pressurized fluid forces lubricant through the outlet 56 as a subnormal rate, which persists until the lubricant reserve is substantially depleted. The subnormal rate is ideally achieved by intermittently releasing lubricant from the reservoir, but may also be achieved by releasing a continuous stream of lubricant at a rate less than the normal rate of release. |
FILED | Thursday, August 14, 2003 |
APPL NO | 10/640999 |
ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
CURRENT CPC | Lubrication 184/6.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 17, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080617.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page