FedInvent™ Patents
Patent Details for Tuesday, August 26, 2008
This page was updated on Monday, March 27, 2023 at 12:59 AM GMT
Department of Defense (DOD)
| US 07415864 | Israel et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Joshua D. Israel (Baltimore, Maryland); Corey L. Piepenburg (Nottingham, Maryland); Malcolm D. Goodman (Forest Hill, Maryland) |
| ABSTRACT | An orifice test calibration device tests the functionality of protective mask testers. The orifice test calibration device has a semi-rigid tubular channel with one end for sealing the flow outlet port of the protective mask tester and a second end for sealing the vacuum inlet port of the protective mask tester. The device also includes a sealable opening within the tubular channel and an insertable orifice plug having a set diameter for insertion into the sealable opening in order to calibrate the protective mask tester. |
| FILED | Thursday, August 31, 2006 |
| APPL NO | 11/468943 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/1.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07415900 | Randolph |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rex N. Randolph (Ridgecrest, California) |
| ABSTRACT | Blast pressure gauges and methods for detecting blast pressure during a blast test. The gauges operate independently of power sources, are portable, and are used in harsh environments including test ranges. Each embodiment is constructed to detect blast pressures as required in the circumstances of a particular blast test. |
| FILED | Wednesday, January 31, 2007 |
| APPL NO | 11/703905 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/862.637 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07415929 | Faughn |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jim A. Faughn (Glen Arm, Maryland) |
| ABSTRACT | Systems for launching one or more projectiles from a bore are provided. An exemplary system incorporates a shell, a projectile, an explosive charge and a wad. The shell includes a base and a casing, with the casing defining an interior. The projectile is located within the interior and is configured to be expelled from the shell casing. The explosive charge is located within the interior and is configured to expel the projectile from the casing. The wad is located within the interior and is configured to expel the projectile from the casing in response to detonation of the explosive charge. The wad includes petals and a petal stop, with the petals being movable between a closed position, in which free ends of the petals are arranged proximate to each other such that the petals at least partially surround the projectile, and an open position, in which the free ends of the petals are displaced from each other, the petal stop being configured to limit movement of the petals beyond the open position. Responsive to being expelled from a bore by detonation of the explosive charge, the petals move from the closed position to the open position, thereby retarding the wad and releasing the projectile. |
| FILED | Wednesday, February 01, 2006 |
| APPL NO | 11/345676 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/457 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416154 | Bittle et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | David A. Bittle (Somerville, Alabama); Gary T. Jimmerson (Athens, Alabama); Julian L. Cothran (Arab, Alabama) |
| ABSTRACT | The Trajectory Correction Kit (TCK) is a completely self-contained retrofit kit that is externally and fixedly mounted as an add-on to the rear (aft of the tailfins) of an existing, unguided rocket. The TCK continuously measures the pitch and yaw of the rocket as it is released from the launch tube and during the initial seconds of the flight and calculates the trajectory correction that is necessary to eliminate the measured pitch and yaw. Then it activates selected thrusters among the thrusters that are positioned around the circumference of the rocket body so as to steer the rocket in a direction until the measured pitch and yaw are eliminated. This results in significant reductions in both the rocket flight path dispersion and collateral damage. |
| FILED | Friday, September 16, 2005 |
| APPL NO | 11/229425 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeronautics and astronautics 244/3.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416158 | Sadeck |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | James E. Sadeck (East Freetown, Massachusetts) |
| ABSTRACT | A continuous disreefing apparatus has a sleeve that has a diameter and is made from a flexible, resilient material that allows the sleeve to diametrically contract when the sleeve is under tension and to diametrically relax when such tension is substantially reduced or removed. The sleeve has a portion thereof configured for connection to a parachute suspension line. The continuous disreefing apparatus includes a reefing line that extends through the sleeve and is arranged for movement through the sleeve wherein the rate at which the reefing line moves through the sleeve is controlled by the amount of tension on the sleeve. |
| FILED | Wednesday, September 21, 2005 |
| APPL NO | 11/239437 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416352 | Goutzoulis et al. |
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| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | Akis Goutzoulis (Annapolis, Maryland); John B. Goodell (Baltimore, Maryland); Gervase J. Willis (Orrtanna, Pennsylvania) |
| ABSTRACT | Various embodiments of the present invention provide optical multi-channel free space interconnects that provide optical channel isolation, thereby reducing crosstalk. |
| FILED | Thursday, September 08, 2005 |
| APPL NO | 11/220651 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416803 | Haile et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sossina M. Haile (Altadena, California); Calum Chisholm (Pasadena, California); Ryan B. Merle (Kent, Washington); Dane A. Boysen (Pasadena, California); Sekharipuram R. Narayanan (Arcadia, California) |
| ABSTRACT | Improved solid acid electrolyte materials, methods of synthesizing such materials, and electrochemical devices incorporating such materials are provided. The stable electrolyte material comprises a solid acid capable undergoing rotational disorder of oxyanion groups and capable of extended operation at elevated temperatures, that is, solid acids having hydrogen bonded anion groups; a superprotonic, trigonal, tetragonal, or cubic, disordered phase; and capable of being operating at temperatures of ˜100° C. and higher. |
| FILED | Thursday, August 01, 2002 |
| APPL NO | 10/211882 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416843 | Ewert et al. |
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| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Matt Ewert (St. Pete Beach, Florida); Phil Amuso (Tampa, Florida); Andrew Cannons (Tampa, Florida) |
| ABSTRACT | The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/035667 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416878 | Nikolich et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Mikeljon Nikolich (Takoma Park, Maryland); David Hoover (Rockville, Maryland) |
| ABSTRACT | Live attenuated vaccines against brucellosis and infection by other diseases are described. It has been discovered that trans complementation of the Brucella wboA gene can be used to maintain an expression vector in an attenuated Brucella host cell in a vaccinee. Further, heterologous antigens can be expressed using this Brucella platform, thus effecting a multivalent vaccine against Brucella and the disease corresponding to the heterologous antigen. |
| FILED | Thursday, December 11, 2003 |
| APPL NO | 10/733691 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417139 | Dellinger et al. |
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| ASSIGNEE(S) | Agilent Technologies, Inc. (Santa Clara, California) |
| INVENTOR(S) | Douglas J Dellinger (Boulder, Colorado); Agnieszka B. Sierzchala (Boulder, Colorado); Marvin H Caruthers (Loveland, Colorado); Geraldine F Dellinger (Boulder, Colorado) |
| ABSTRACT | Methods of forming an internucleotide bond are disclosed. Such methods find use in synthesis of polynucleotides. The method involves contacting a functionalized support with a precursor having an exocyclic amine triaryl methyl protecting group under conditions and for a time sufficient to result in internucleotide bond formation. The functionalized support includes a solid support, a triaryl methyl linker group, and a nucleoside moiety having a reactive site hydroxyl, the nucleoside moiety attached to the solid support via the triaryl methyl linker group. In particular embodiments, the precursor has the structure: wherein: O and H represent oxygen and hydrogen, respectively R1 is hydrido, hydroxyl, protected hydroxyl, lower alkyl, modified lower alkyl, or alkoxy, one of R2 or R3 is a hydroxyl protecting group; and the other of R2 or R3 is a reactive group capable of reacting with the reactive site hydroxyl, Base is a heterocyclic base having an exocyclic amine group, and Tram is the exocyclic amine triaryl methyl protecting group. |
| FILED | Saturday, August 30, 2003 |
| APPL NO | 10/652054 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/25.340 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417219 | Catrysse et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Peter B. Catrysse (Palo Alto, California); Hocheol Shin (Stanford, California); Shanhui Fan (Stanford, California) |
| ABSTRACT | Using a realistic plasmonic model, an optically thick electrically conductive film with subwavelength hole or holes therein is shown to always support propagating modes near the surface plasmon frequency, where cross-sectional dimensions of the hole or holes are less than about λ/2nh, λ being the wavelength of the light and nh the refractive index of the dielectric material in the hole or holes. This is the case even when material losses are taken into account. Based on the dispersion analysis, in both a single hole or hole array designs, propagating modes play a dominant role in the transport properties of incident light. These structures exhibit a new region of operation, while featuring a high packing density and diffraction-less behavior. These structures can be used in near-field scanning optical microscopy, in collection and emission modes, for writing data to an optical storage device, as wavelength-selective optical filters, for multispectral imaging of a sample, as photolithography masks for transferring an image to a photoresist-coated substrate, as light emitters, light collectors and light modulators. |
| FILED | Wednesday, September 20, 2006 |
| APPL NO | 11/533719 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/234 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417234 | Hastings et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeffrey T. Hastings (Lexington, Kentucky); James G. Goodberlet (Melrose, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Henry I. Smith (Sudbury, Massachusetts) |
| ABSTRACT | A method or system of spatial-phase locking a beam used in maskless lithography provides a fiducial grid with a single spatial-period, the fiducial grid being rotated at an angle with respect to a direction of scanning the beam; detects a signal generated in response to the beam being incident upon the fiducial grid; determines frequency components of the detected signal; and determines a two-dimensional location of the beam from phases of two determined fundamental frequency component. The method or system further determines a size of the beam from relative amplitudes of the determined fundamental and harmonic frequency components and/or determine a shape of the beam from relative amplitudes of the determined fundamental and harmonic frequency components. The method or system corrects a deflection of the beam in response to the determined two-dimensional location, and/or adjusts the size of the beam in response to the determined size, and/or adjusts the shape of the beam in response to the determined shape. If the method or system spatial-phase locks a plurality of beams used in maskless lithography, a fiducial grid with a varying spatial-period is utilized. In the plural beam method or system, the frequency components for each beam are determined using frequency-division multiplexing. |
| FILED | Tuesday, May 17, 2005 |
| APPL NO | 11/130892 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/397 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417516 | Singh |
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| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Donald R. Singh (Apple Valley, Minnesota) |
| ABSTRACT | A monolithic integrated circuit for performing power dividing and power monitoring functions is disclosed. The monolithic integrated circuit includes a power dividing portion for dividing radio frequency (RF) signal power and a power monitoring portion for monitoring the RF signal power. In one example, the monolithic integrated circuit is a microwave monolithic integrated circuit (MMIC) for use in high-frequency applications within microwave and millimeter-wave frequency range. |
| FILED | Monday, November 14, 2005 |
| APPL NO | 11/272650 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/109 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417666 | Kaltenbacher et al. |
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| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Eric A. Kaltenbacher (St. Petersburg, Florida); James T. Patten (Sarasota, Florida); Kendall L. Carder (St. Petersburg, Florida); David K. Costello (St. Petersburg, Florida); John R. Kloske (St. Petersburg, Florida) |
| ABSTRACT | The invention is directed to a remote 3-D imaging system which uses a novel illumination source to establish the relationship of the image features to the system, which is displayed by virtue of calculations. In addition to static surfaces, moving surfaces may be studied and corrections due to turbidity and platform position are also easily compensated for. The instant system may also contain a plurality of sensing systems based on light, including traditional reflective or elastic scattering and novel fluorescent or non-elastic scattering still and video imaging systems, including time-gated systems. |
| FILED | Thursday, April 01, 2004 |
| APPL NO | 10/815489 |
| ART UNIT | 2621 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/81 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417727 | Polonskiy et al. |
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| ASSIGNEE(S) | Clean Earth Technologies, LLC (, None) |
| INVENTOR(S) | Leonid Polonskiy (St. Louis, Missouri); Jeffry Golden (Creve Coeur, Missouri); Clinton Boyd (St. Peters, Missouri); Arie Kaplan (University City, Missouri); Lawrence Hanebrink (Chesterfield, Missouri); Qingzhong (James) Cai (Plano, Texas); Andrew Cilia (McKinney, Texas) |
| ABSTRACT | A method for remotely detecting whether a subject is alive, comprising the steps of determining a calibration spectral signature for light reflectance from living skin, normalizing the calibration spectral signature values to the calibration reflectance value at a reference wavelength, storing the normalized calibration spectral signature, determining a subject spectral signature of the light reflectance of a region of skin of the subject whose liveness is to be determined, normalizing the subject spectral signature values to the subject reflectance value at the reference wavelength, comparing the normalized subject spectral signature with the normalized calibration spectral signature for at least one wavelength, generating a subject liveness signal based on the comparison of the normalized subject spectral signature with the normalized calibration spectral signature, and emitting the subject liveness signal. |
| FILED | Wednesday, December 07, 2005 |
| APPL NO | 11/296804 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417889 | Chuang et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ching-Te Chuang (South Salem, New York); Jae-Joon Kim (Yorktown Heights, New York); Keunwoo Kim (Somers, New York) |
| ABSTRACT | Techniques are provided for employing independent gate control in asymmetrical memory cells. A memory circuit, such as an SRAM circuit, can include a number of bit line structures, a number of word line structures that intersect the bit line structures to form a number of cell locations, and a number of asymmetrical memory cells located at the cell locations. Each of the asymmetrical cells can be selectively coupled to a corresponding one of the bit line structures under control of a corresponding one of the word line structures. Each of the cells can include a number of field effect transistors (FETS), and at least one of the FETS can be configured with separately biased front and back gates. One gate can be biased separately from the other gate in a predetermined manner to enhance read stability of the asymmetrical cell. |
| FILED | Monday, February 27, 2006 |
| APPL NO | 11/362612 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417993 | Ebergen et al. |
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| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Josephus C. Ebergen (San Francisco, California); Ivan E. Sutherland (Santa Monica, California); Robert J. Drost (Mountain View, California) |
| ABSTRACT | One embodiment of the present invention provides a system for high-throughput asynchronous communication that includes a sender and a receiver. A sender's first-in, first-out (FIFO) buffer is coupled to an input of the sender, a receiver's FIFO buffer is coupled to an input of the receiver, a forward communication channel is coupled between the sender and the receiver's FIFO buffer, and a reverse communication channel is coupled between the receiver and the sender's FIFO buffer. The forward communication channel, the receiver's FIFO buffer, the reverse communication channel, and the sender's FIFO buffer operate collectively as a network FIFO between the sender and the receiver. The network FIFO is configured to ensure that asynchronous communication between the sender and the receiver takes place reliably and without unnecessary waiting by the sender or the receiver. |
| FILED | Thursday, December 18, 2003 |
| APPL NO | 10/742075 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Multiplex communications 370/395.720 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418166 | Kapur et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Pawan Kapur (Palo Alto, California); Yu-Hsuan Kuo (Taipei, Taiwan); Michael West Wiemer (Los Altos, California); David A. B. Miller (Stanford, California) |
| ABSTRACT | Optical devices having integrated waveguide and active areas are realized using a crystallization approach involving the inhibition of defects typically associated with liquid-phase crystalline growth of lattice mismatched materials. According to one example embodiment, a growth region is formed such that the region is isolated from a silicon portion of silicon material. The region extends from a silicon-based seeding area of the substrate. A semiconductor material is deposited on a Silicon-based seeding area and in the growth region. A single crystalline material is formed from the deposited semiconductor material by heating and cooling the deposited semiconductor material while directing growth of the semiconductor material from the Silicon-based seeding area and through an opening sufficiently narrow to mitigate crystalline defects. A light-communicating device is formed by etching the silicon material over an insulator layer and etching the single crystalline material. |
| FILED | Friday, February 23, 2007 |
| APPL NO | 11/710624 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418169 | Tearney et al. |
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| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Guillermo J. Tearney (Cambridge, Massachusetts); Milen Shishkov (Watertown, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Benjamin J. Vakoc (Cambridge, Massachusetts) |
| ABSTRACT | An apparatus for controlling at least one of at least two sections of at least one fiber can be provided. The apparatus can include an arrangement which may be provided between the first and second sections of a particular continuous fiber of the fibers. A particular one of the first and second sections may be provided in a particular orientation that is perpendicular to an extension of the particular fiber. The arrangement is capable of controlling the particular fiber such that the particular one of the sections is capable of being rotated for at least 360° with respect to the particular orientation. The arrangement can include a further arrangement that is capable of at least partially wrapping the particular fiber around the second arrangement, and controlling the particular fiber such that the particular one of the sections is capable of being rotated with respect to the particular orientation during a transmission of the electro-magnetic radiation. |
| FILED | Thursday, February 01, 2007 |
| APPL NO | 11/670069 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418353 | Lovell et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Edward G. Lovell (Madison, Wisconsin); Zhaohua Feng (Changchun, China PRC); Roxann L. Engelstad (Madison, Wisconsin) |
| ABSTRACT | A method for determining the stresses in a film applied to a substrate from measured substrate shape. The substrate is first analyzed using finite element techniques to obtain nodal forces at the surface of the substrate to which the film is applied, based on measured distortion data of the substrate surface. The film is then analyzed to calculate the film stresses from the applied nodal forces using finite element techniques. The invention may be applied to determine stresses in thin films applied to a variety of substrates, including those used for micro-electronic (e.g., integrated circuit) and micro-mechanical devices and/or for the lithography masks or other optical/projection systems used to fabricate such devices. |
| FILED | Friday, October 07, 2005 |
| APPL NO | 11/245938 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/42 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418401 | Bogasky et al. |
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| ASSIGNEE(S) | Accenture Global Services GmbH (Schaffhausen, Switzerland) |
| INVENTOR(S) | John J. Bogasky (Silver Spring, Maryland); Carl Almond (Tampa, Florida); Andrew Schaefer (Hoboken, New Jersey) |
| ABSTRACT | The present invention is directed to a secure electronic registration and voting solution incorporating integrated end-to-end voting system architecture and processes providing secure identification and authentication, voter registration, ballot definition, ballot presentation to the voter, voting, and ballot tabulation via secure transmission over the network. The disclosed embodiments of the present invention describe an integrated solution to voting via a network, such as the Internet. A user logs into the system using through an application on a local computer that presents an electronic ballot to a user and accepts the user's voting selections. The voting selections are then associated with the user's login data and an identifier for the local computer. The local application than encrypts the voting data and forwards a server that authenticates the encrypted voting data using the user login and the computer identifier. The still-encrypted voting data is then stored. |
| FILED | Friday, July 08, 2005 |
| APPL NO | 11/176685 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07418432 — Adaptive control system having direct output feedback and related apparatuses and methods
| US 07418432 | Calise et al. |
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| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Anthony J. Calise (Atlanta, Georgia); Naira Hovakimyan (Smyrna, Georgia); Moshe Idan (Haifa, Israel) |
| ABSTRACT | An adaptive control system (ACS) uses direct output feedback to control a plant. The ACS uses direct adaptive output feedback control developed for highly uncertain nonlinear systems, that does not rely on state estimation. The approach is also applicable to systems of unknown, but bounded dimension, whose output has known, but otherwise arbitrary relative degree. This includes systems with both parameter uncertainty and unmodeled dynamics. The result is achieved by extending the universal function approximation property of linearly parameterized neural networks to model unknown system dynamics from input/output data. The network weight adaptation rule is derived from Lyapunov stability analysis, and guarantees that the adapted weight errors and the tracking error are bounded. |
| FILED | Tuesday, April 12, 2005 |
| APPL NO | 11/105826 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418630 | Vick et al. |
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| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Christopher A. Vick (San Jose, California); Lawrence G. Votta (Sammamish, Washington) |
| ABSTRACT | A method for safepointing a system that includes receiving a stop command by an executing thread from a master, wherein the executing thread executes an operating system, continuing execution of the executing thread until a safepoint is reached after receiving the stop command, halting execution of the executing thread at the safepoint; and evaluating a response from the executing thread to diagnosis the system. |
| FILED | Wednesday, September 07, 2005 |
| APPL NO | 11/220507 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418641 | Drake et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alan J. Drake (Round Rock, Texas); Aj KleinOsowski (Austin, Texas); Andrew K. Martin (Austin, Texas) |
| ABSTRACT | A latch circuit having three latch stages generates a majority output value from the stages, senses when the latch stage outputs are not all equal, and feeds the majority output value back to inputs of the latch stages to reload the latch stages. The latch circuit uses a not-equal gate whose output is an error signal that can be monitored to determine when a single-event upset has occurred. A master stage is controlled by a first multiplexer which receives one system clock signal, while a slave stage is controlled by a second multiplexer which receives another system clock signal, and the latch stage outputs are connected to respective inputs of the not-equal gate, whose output is connected to second inputs of the multiplexers. The latch circuit is part of a latch control system, and reloading of the latch stages takes less than one cycle of the system clock (less than 500 picoseconds). |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/242491 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/726 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 07416550 | Protsenko et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Dmitry E. Protsenko (Costa Mesa, California); Brian J. F. Wong (Irvine, California); Guillermo Aguilar-Mendoza (Corona, California); Ki-Hong Kevin Ho (San Francisco, California); Sergio Diaz (Pamplona, Spain) |
| ABSTRACT | A method of electroforming tissue comprises creating stress in the tissue; and causing a direct current to flow in the tissue to change the stress, strain, or intrinsic mechanical properties including shape of the tissue. Force is mechanically applied to the tissue to create external stresses or material parameters of the tissue are used to create internal stresses in the tissue by causing a current to flow in the tissue. The method further comprises the step of monitoring the stresses in the tissue and controlling the current flowing in the tissue according to the stresses therein by monitoring impedance, the optical properties, the pH, acoustic properties of the tissue, the gas formation in the tissue, the color of the tissue as caused by a chemical dye disposed therein or as caused by electroplating a material thereon. |
| FILED | Thursday, January 22, 2004 |
| APPL NO | 10/762639 |
| ART UNIT | 3739 — Optics |
| CURRENT CPC | Surgery 66/41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416724 | Guan |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Kun-Liang Guan (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for identifying abnormalities in TSC signaling pathways. In particular, the present invention relates to methods of diagnosing and treating disorders such as tuberous sclerosis, which are caused by mutations in the TSC genes. The present invention further relates to methods and compositions for treating cancers mediated by TSC signaling disorders. |
| FILED | Thursday, December 21, 2006 |
| APPL NO | 11/643443 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416726 | Ravetch |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Jeffrey V. Ravetch (New York, New York) |
| ABSTRACT | The present invention is related to enhancing the function of anti-tumor antibodies by regulating FcγRIIB-mediated activity. In particular, disrupting SHIP activation by FcγRIIB enhances cytotoxicity elicited by a therapeutic antibody in vivo in a human. The invention further provides an antibody, e.g., an anti-tumor antibody, with a variant Fc region that results in binding of the antibody to FcγRIIB with reduced affinity. A variety of transgenic mouse models demonstrate that the inhibiting FcγRIIB molecule is a potent regulator of cytotoxicity in vivo. |
| FILED | Friday, April 13, 2001 |
| APPL NO | 09/834321 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416731 | Thompson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Carnegie Institution of Washington (Washington, District of Columbia) |
| INVENTOR(S) | Catherine C. Thompson (Baltimore, Maryland) |
| ABSTRACT | The novel nucleotide sequence and deduced amino acid sequence of the human Hairless gene and protein, respectively, are disclosed. A Hairless expression construct may be used in transcription assays. Moreover, processes of making and using the aforementioned products in screening assays which affect Hairless-regulated transcription are disclosed. Kits comprising a polynucleotide, polypeptide, specific binding molecule, or combinations thereof are disclosed. |
| FILED | Monday, July 18, 2005 |
| APPL NO | 11/182885 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416840 | Zhu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Qing Zhu (Emeryville, California); Ju-Tao Guo (Lansdale, Pennsylvania); Christoph Seeger (Elkins Park, Pennsylvania) |
| ABSTRACT | Cells and cell lines which replicate HCV of non-hepatic human and non human origin are disclosed. Also provided are methods of using such cells and cell lines to identify anti-HCV agents for the treatment of HCV infection. |
| FILED | Friday, December 12, 2003 |
| APPL NO | 10/536955 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416844 | Korlach et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Monday, November 21, 2005 |
| APPL NO | 11/285422 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416850 | Jemmerson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald R. Jemmerson (Minneapolis, Minnesota) |
| ABSTRACT | The present invention relates generally to assays and methods involving Cytochrome c (Cyt c) and leucine-rich alpha-2-glycoprotein-1 (LRG), and related antibodies. In an embodiment, the invention includes a method of detecting LRG in a sample, the method including disposing Cyt c on a substrate; contacting the sample with the Cyt c; contacting bound components of the sample with an antibody or antibody fragment specific for LRG; and quantitating the amount of the antibody or antibody fragment bound to LRG. In an embodiment, the invention includes a method of purifying or enhancing the purity of LRG from a sample, the method including contacting the sample with Cyt c; forming a complex between LRG in the sample and Cyt c; removing uncomplexed components of the sample; releasing LRG from the complex with Cyt c; and collecting the released LRG. In an embodiment, the invention includes an isolated antibody produced by a hybridoma cell line (ATCC Accession Number PTA-8131), or antibody fragment thereof that specifically binds to LRG. In an embodiment, the invention includes a kit comprising an antibody that specifically binds to LRG, or a fragment thereof that specifically binds to LRG, and a compartment, wherein the antibody or fragment is contained within the compartment. Other embodiments are described herein. |
| FILED | Thursday, January 25, 2007 |
| APPL NO | 11/627164 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416852 | Progulske-Fox et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation (Gainesville, Florida) |
| INVENTOR(S) | Ann Progulske-Fox (Keystone Heights, Florida); Jeffrey Daniel Hillman (Gainesville, Florida); Martin Handfield (Gainesville, Florida) |
| ABSTRACT | The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis. |
| FILED | Tuesday, August 10, 2004 |
| APPL NO | 10/915002 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416872 | Croteau et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington State University Research Foundation (Pullman, Washington) |
| INVENTOR(S) | Rodney B. Croteau (Pullman, Washington); Anne Schoendorf (Bossey, France); Stefan Jennewein (Pullman, Washington) |
| ABSTRACT | Oxygenase enzymes and the use of such enzymes to produce paclitaxel (Taxol™), related taxoids, as well as intermediates in the Taxol biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the oxygenase enzymes. |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/242662 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416875 | Raines et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Julie C. Mitchell (Madison, Wisconsin); Thomas J. Rutkoski (Madison, Wisconsin) |
| ABSTRACT | This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the ribonuclease inhibitor while still retaining catalytic properties. While earlier work had identified some modifications to RNase A that would result in cytotoxicity, the use of the FADE algorithm for molecular interaction analysis has led to several other locations that were candidates for modification. Some of those modifications did result in RNase A variants with increase cytotoxicity. |
| FILED | Friday, June 16, 2006 |
| APPL NO | 11/454379 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/196 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416893 | DeBernardi et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Atto Bioscience (Rockville, Maryland) |
| INVENTOR(S) | Maria A. DeBernardi (Potomac, Maryland); Gary Brooker (Rockville, Maryland) |
| ABSTRACT | The present invention relates to methods of identifying drug-resistant and/or drug-sensitive cells, for example, breast cancer and brain tumor cells, on the basis of different ion and/or second messenger dynamics between a drug-sensitive and drug-resistant cell. For example, the invention provides measuring the comparative decay rates of a cellular ion, such as calcium, released into the intracellular compartment of drug sensitive and/or drug resistant cells. The present invention also provides methods for screening compounds that modulate the ionic dynamics of a cell as well as methods of determining drug resistance/sensitivity of cancer cells from cancer patients and/or designing cancer therapy based on of the ionic dynamics of cancer cells from a particular patient. |
| FILED | Friday, December 06, 2002 |
| APPL NO | 10/313039 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416903 | Sklar et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Larry A. Sklar (Albuquerque, New Mexico); Andrea A. Mammoli (Albuquerque, New Mexico); Richard A. Truesdell (Albuquerque, New Mexico); Peter V. Vorobieff (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides methods and apparatus for mixing samples in-line in a microfluidic system, comprising methods of and means for introducing a first fluid sample into a flow-tube at a first end at a first velocity via a first conduit; methods of and means for introducing a second fluid sample into the flow-tube at the first end at a second velocity, the second velocity different from the first velocity, via a second conduit, wherein the first fluid sample and the second fluid sample converge in the flow tube to form an interface; whereby the first fluid sample and the second fluid sample mix at the interface within the flow-tube, wherein fluid flow at the first end of the flow-tube is laminar and fluid flow at a second end of the flow-tube is laminar, and wherein the flow-tube has a constant diameter between the first end and the second end of the flow-tube. |
| FILED | Monday, May 05, 2003 |
| APPL NO | 10/428931 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/180 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417026 | Williams et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | David A. Williams (Cincinnati, Ohio); Yi Zheng (Cincinnati, Ohio) |
| ABSTRACT | Improved methods and pharmaceutical compositions are provided herein for mobilizing hematopoietic progenitor cells from bone marrow into peripheral blood, comprising the administration of an effective amount of an inhibitor of GTPases, such as Rac1 and Rac2 alone or in combination. Specifically, methods are disclosed for mobilizing hematopoietic stem cells into a subject's peripheral blood. In particular, embodiments of the method involve inhibition of both Rac1 and Rac2 GTPases to increase the numbers of hematopoietic stem cells into a subject's peripheral blood of a subject. The subject's blood can be processed and used to repopulate the destroyed lymphohematopoietic system of a recipient and may in the future be utilized to repair a variety of non-hematopoietic tissues. Therefore, hematopoietic stem cells mobilized into a subject's peripheral blood by the method of the invention is useful as a source of donor cells in bone marrow transplantation for the treatment of a variety of disorders, including cancer, anemia, autoimmunity and immunodeficiency. They can also be used for increasing white blood cell survival and for chemotherapy. |
| FILED | Thursday, August 12, 2004 |
| APPL NO | 10/918328 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417072 | Malter et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James S. Malter (Madison, Wisconsin); Stephane Esnault (Madison, Wisconsin); Zhong-Jian Shen (Madison, Wisconsin) |
| ABSTRACT | The invention provides pharmaceutical compositions and methods of treating immunological disorders. The invention also provides pharmaceutical compositions and methods of inducing eosinophil apoptosis, and methods for treating eosinophil-associated disorders comprising inducing eosinophil apoptosis in an individual in need thereof. |
| FILED | Friday, May 12, 2006 |
| APPL NO | 11/383127 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/682 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417120 | Vinkemeier et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Uwe Vinkemeier (New York, New York); James E. Darnell, Jr. (Larchmont, New York) |
| ABSTRACT | The present invention describes methods of producing milligram quantities of three forms of purified Stat1 protein from recombinant DNA constructs. In addition, the Stat proteins may be isolated in their phosphorylated or nonphosphorylated forms (Tyr 701). The proteins can be produced in baculovirus infected insect cells, or E. coli. A compact domain in the amino terminus of Stat1α was isolated and found to enhance DNA binding due to its ability to interact with a neighboring Stat protein. A relatively protease-resistant recombinant truncated form of the Stat protein was isolated in 40-50 mg quantities. Purification of the Stat proteins were performed after modifying specific cysteine residues of the Stat proteins to prevent aggregation. Activated EGF-receptor partially purified from membranes by immunoprecipitation was shown to be capable of in vitro catalysis of the phosphorylation of the tyrosine residue of Stat1 known to be phosphorylated in vivo. Techniques are enclosed to separate the phosphorylated from the nonphosphorylated Stat proteins. The techniques disclosed are general for Stat proteins and may be used to isolate large quantities of purified Stat 2, 3, 4, 5A, 5B and 6. Methods for using purified Stat proteins, truncated Stat proteins, or Stat N-terminal fragments for drug discovery are also disclosed. |
| FILED | Thursday, January 19, 2006 |
| APPL NO | 11/335005 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417136 | Chang |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Gwong-Jen J. Chang (Fort Collins, Colorado) |
| ABSTRACT | The invention encompasses nucleic acid molecules containing transcription units which encode the flavivirus M and E protein antigens. The flaviviruses include Japanese encephalitis virus, dengue, yellow fever virus and St. Louis encephalitis virus. The nucleic acids function to provide the M and E protein antigens when the nucleic acid resides in an appropriate host cell, especially when the host cell is the cell of a subject. The invention also encompasses a vaccine whose active agent is the nucleic acid. The invention further encompasses the cultured host cells when they contain within them nucleic acid molecules containing the transcription units. The invention in addition encompasses a method of immunizing a subject against flavivirus infection by administering to the subject an effective amount of a vaccine containing a nucleic acid molecule containing the transcription unit of the invention. |
| FILED | Thursday, June 03, 1999 |
| APPL NO | 09/701536 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.720 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417156 | Posner et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Gary H. Posner (Baltimore, Maryland); Theresa A. Shapiro (Towson, Maryland); Surojit Sur (Baltimore, Maryland); Tanzina Labonte (Baltimore, Maryland); Kristina Borstnik (State College, Pennsylvania); Ik-Hyeon Paik (Baltimore, Maryland); Andrew J. McRiner (Baltimore, Maryland) |
| ABSTRACT | In only two steps and in 65% overall yield, natural trioxane artemisinin (I) was converted on gram scale into C-10-carba trioxane dimer (3). This new, very stable dimer was then transformed easily in one additional step into four different dimers (4-7). Alcohol and diol dimers (4 and 5) and ketone dimer (7) are 10 times more antimalarially potent in vitro than artemisinin (I), and alcohol and diol dimers (4 and 5) are strongly inhibitory but not cytotoxic toward several human cancer cell lines. Water-soluble carboxylic acid derivatives (8a-10c and 12) were easily prepared from dimers (4-6); they are thermally stable even at 60° C. for 24 hours, are more orally efficacious as antimalarials than either artelinic acid or sodium artesunate, and have potent and selective anticancer activities. Further derivitization of the alcohol dimers (4 and 17), diol dimer (5) and ketone (7) has produced a number of analogs also antimalarially active in vitro at sub-nanomolar concentrations (most notably: pyridine N-oxides (13, 15, 18, 23, 24 and 25), phosphoric acid triesters (26 and 27), sulfonamide (40) and cyclic carbonate (41)). In addition, dimers (13 and 19) are more efficacious (when administered both orally and i.v.) and less toxic (when administered intraperitoneally to mice as a single dose) than clinically-used sodium artesunate, thereby giving them a better antimalarial therapeutic index than sodium artesunate. |
| FILED | Friday, September 26, 2003 |
| APPL NO | 10/529513 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/348 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417158 | Tidwell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Richard R. Tidwell (Pittsboro, North Carolina); Karl Werbovetz (Worthington, Ohio); Scott Gary Franzblau (Chicago, Illinois); Svetlana Bakunova (Chapel Hill, North Carolina); Stanislav Bakunov (Chapel HIll, North Carolina) |
| ABSTRACT | A method of treating a Mycobacterium tuberculosis infection in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of treating microbial infections, including infections from protozoan pathogens, such as Leishmania donovani, Trypanosoma brucei rhodesiense, a Trypanosoma cruzi, and Plasmodium falciparum, and fungal pathogens, such as Candida albicans, Aspergillus fumigatus, and Cryptococcus neoformans, in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of synthesizing novel cationic substituted benzofuran compounds and the novel compounds themselves. |
| FILED | Monday, December 06, 2004 |
| APPL NO | 11/005524 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/471 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418123 | Giger et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Maryellen L. Giger (Elmhurst, Illinois); Ioana Bonta (Chicago, Illinois); Ruth Heimann (Burlington, Vermont); Robert M. Nishikawa (Batavia, Illinois); Carl J. Vyborny (Riverside, Illinois) |
| ABSTRACT | An automated method for determining prognosis based on an analysis of abnormality (lesion) features and parenchymal features obtained from medical image data of a patient. The techniques include segmentation of lesions from radiographic images, extraction of lesion features, and a merging of the features (with and without clinical information) to yield as estimate of the prognosis for the specific case. An example is given for the prognosis of breast cancer lesions using mammographic data. A computerized image analysis system for assessing prognosis combines the computerized analysis of medical images of cancerous lesions with the training-based methods of assessing prognosis of a patient, using indicators such as lymph node involvement, presence of metastatic disease, local recurrence, and/or death. It is expected that use of such a system to assess the severity of the disease will aid in improved decision-making regarding treatment options. |
| FILED | Monday, July 14, 2003 |
| APPL NO | 10/617675 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418401 | Bogasky et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Accenture Global Services GmbH (Schaffhausen, Switzerland) |
| INVENTOR(S) | John J. Bogasky (Silver Spring, Maryland); Carl Almond (Tampa, Florida); Andrew Schaefer (Hoboken, New Jersey) |
| ABSTRACT | The present invention is directed to a secure electronic registration and voting solution incorporating integrated end-to-end voting system architecture and processes providing secure identification and authentication, voter registration, ballot definition, ballot presentation to the voter, voting, and ballot tabulation via secure transmission over the network. The disclosed embodiments of the present invention describe an integrated solution to voting via a network, such as the Internet. A user logs into the system using through an application on a local computer that presents an electronic ballot to a user and accepts the user's voting selections. The voting selections are then associated with the user's login data and an identifier for the local computer. The local application than encrypts the voting data and forwards a server that authenticates the encrypted voting data using the user login and the computer identifier. The still-encrypted voting data is then stored. |
| FILED | Friday, July 08, 2005 |
| APPL NO | 11/176685 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07416699 | Dai et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Hongjie Dai (Sunnyvale, California); Jing Kong (Menlo Park, California) |
| ABSTRACT | Nanotubes and nanotube-based devices are implemented in a variety of applications. According to an example embodiment of the present invention, a nanotube is adapted to pass current between two conductive elements. In one implementation, each conductive element includes a catalyst material, wherein electrical connection is made to opposite ends of the nanotube at each of the catalyst portions. In one implementation, the electrical connection is used to detect an electrical characteristic of the nanotube, such as the response of the nanotube to exposure to one or more of a variety of materials. In another implementation, the nanotube is used for chemical and biological sensing. In still another implementation, a particular functionality is imparted to the nanotube using one or more of a variety of materials coupled to the nanotube, such as metal particles, biological particles and/or layers of the same. |
| FILED | Tuesday, June 18, 2002 |
| APPL NO | 10/175026 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416803 | Haile et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sossina M. Haile (Altadena, California); Calum Chisholm (Pasadena, California); Ryan B. Merle (Kent, Washington); Dane A. Boysen (Pasadena, California); Sekharipuram R. Narayanan (Arcadia, California) |
| ABSTRACT | Improved solid acid electrolyte materials, methods of synthesizing such materials, and electrochemical devices incorporating such materials are provided. The stable electrolyte material comprises a solid acid capable undergoing rotational disorder of oxyanion groups and capable of extended operation at elevated temperatures, that is, solid acids having hydrogen bonded anion groups; a superprotonic, trigonal, tetragonal, or cubic, disordered phase; and capable of being operating at temperatures of ˜100° C. and higher. |
| FILED | Thursday, August 01, 2002 |
| APPL NO | 10/211882 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416844 | Korlach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Monday, November 21, 2005 |
| APPL NO | 11/285422 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416870 | Shen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ben Shen (Verona, Wisconsin); Hyung-Jin Kwon (Austin, Wisconsin) |
| ABSTRACT | The present invention provides methods of modifying a biological molecule by C—O bond formation utilizing a type II polyketide synthase (PKS) system from the nonactin biosynthesis gene cluster. The type II PKS responsible for biosynthesis of the macrotetralide nonactin includes polypeptides encoded by the nonJK genes. The NonJ and NonK polypeptides have been identified by the inventors as ketoacyl synthases capable of directly catalyzing C—O bond formation between substrate molecules. This invention increases the scope and diversity of chemical syntheses available for drug design and combinatorial biosynthesis. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646664 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416884 | Gemmiti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Christopher Vinson Gemmiti (Jonesboro, Georgia); Robert E. Guldberg (Marietta, Georgia) |
| ABSTRACT | A bioreactor and methods of using same for making tissue constructs and for conditioning tissue-engineered constructs and harvested tissues such as cryopreserved tissues. The bioreactor allows for static and dynamic culture/conditioning. The bioreactor is dual chambered (one chamber above and one below the cells or construct) to allow for application of biochemical and/or biomechanical stimuli to each side of the cells/construct. |
| FILED | Thursday, February 26, 2004 |
| APPL NO | 10/788135 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/293.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417096 | McCormick, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern Mississippi (Hattiesburg, Mississippi) |
| INVENTOR(S) | Charles L. McCormick, III (Hattiesburg, Mississippi); Andrew B. Lowe (Hattiesburg, Mississippi); Brent S. Sumerlin (Pittsburgh, Pennsylvania) |
| ABSTRACT | A new, facile, general one-phase method of generating thiol-functionalized transition metal nanoparticles and surface modified by (co)polymers synthesized by the RAFT method is described. The method includes the steps of forming a (co)polymer in aqueous solution using the RAFT methodology, forming a collidal transition metal precursor solution from an appropriate transition metal; adding the metal precursor solution or surface to the (co)polymer solution, adding a reducing agent into the solution to reduce the metal colloid in situ to produce the stabilized nanoparticles or surface, and isolating the stabilized nanoparticles or surface in a manner such that aggregation is minimized. The functionalized surfaces generated using these methods can further undergo planar surface modifications, such as fuctionalization with a variety of different chemical groups, expanding their utility and application. |
| FILED | Wednesday, October 25, 2006 |
| APPL NO | 11/586126 |
| ART UNIT | 1796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Synthetic resins or natural rubbers 526/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417112 | Rathore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Osman Rathore (Jacksonville, Florida); Dotsevi Y. Sogah (Ithaca, New York) |
| ABSTRACT | Replacement of the amorphous peptide domain of a structural biopolymer, such as silk from silkworms or spiders, with a nonpeptide segment while maintaining the β-sheet forming crystalline segments provides synthetic multiblock copolymers having solid-state structures and mechanical properties similar to the naturally occurring structural biopolymer is described herein. Such synthetic multiblock copolymers may be produced as films or fibers. |
| FILED | Monday, April 25, 2005 |
| APPL NO | 11/113494 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417174 | Hicks, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Wesley L. Hicks, Jr. (Angola, New York); Rena Bizios (Troy, New York); Frank V. Bright (Williamsville, New York); Joseph A. Gardella (Buffalo, New York); Robert Hard (Buffalo, New York); Jamson S. Lwebuga-Mukasa (Getzville, New York); Alexander N. Cartwright (Williamsville, New York); Bahattin Koc (Amherst, New York) |
| ABSTRACT | The present invention provides a reepithelialization/wound healing implant device comprising a barrier layer and one or more polymer layers doped with agents that promote one or more processes in reepithelialization/wound healing. The implant: [a] provides a temporary mechanical/chemical barrier to species within the external environment that inhibit epithelial migration (e.g., unbalanced production/expression of granulation tissue, inhibitory proteins); [b] biodegrades at an appropriate rate while tissue remodeling is occurring; and [c] delivers active cytokines and growth factors in a choreographed pattern to promote reepithelialization. |
| FILED | Thursday, November 11, 2004 |
| APPL NO | 10/986547 |
| ART UNIT | 3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery: Splint, brace, or bandage 62/41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417219 | Catrysse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Peter B. Catrysse (Palo Alto, California); Hocheol Shin (Stanford, California); Shanhui Fan (Stanford, California) |
| ABSTRACT | Using a realistic plasmonic model, an optically thick electrically conductive film with subwavelength hole or holes therein is shown to always support propagating modes near the surface plasmon frequency, where cross-sectional dimensions of the hole or holes are less than about λ/2nh, λ being the wavelength of the light and nh the refractive index of the dielectric material in the hole or holes. This is the case even when material losses are taken into account. Based on the dispersion analysis, in both a single hole or hole array designs, propagating modes play a dominant role in the transport properties of incident light. These structures exhibit a new region of operation, while featuring a high packing density and diffraction-less behavior. These structures can be used in near-field scanning optical microscopy, in collection and emission modes, for writing data to an optical storage device, as wavelength-selective optical filters, for multispectral imaging of a sample, as photolithography masks for transferring an image to a photoresist-coated substrate, as light emitters, light collectors and light modulators. |
| FILED | Wednesday, September 20, 2006 |
| APPL NO | 11/533719 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/234 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417468 | Verbauwhede et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ingrid M. Verbauwhede (Palo Alto, California); Kris J. V. Tiri (Genk, Belgium) |
| ABSTRACT | A dynamic and differential CMOS logic style is disclosed in which a gate uses a fixed amount of energy per evaluation event. The gate switches its output at every event and loads a constant capacitance. The logic style is a Dynamic and Differential Logic (DDL) style. The DDL style logic typically has one charging event per clock cycle and the charging event does not depend on the input signals. The differential feature masks the in-put value because a precharged output nodes is discharged during the evaluation phase. The dynamic feature breaks the input sequence: the discharged node is charged during the subsequent precharge phase. |
| FILED | Friday, September 17, 2004 |
| APPL NO | 10/565551 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Electronic digital logic circuitry 326/112 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418147 | Kamaci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Nejat Kamaci (Marietta, Georgia); Yucel Altunbasak (Atlanta, Georgia); Russell Manning Mersereau (Atlanta, Georgia) |
| ABSTRACT | Embodiments of a coding system and method are disclosed. One method embodiment includes determining a Cauchy-based probability density function fit to a statistical distribution of coefficients generated from a transformed image frame block that are to be quantized, and estimating rate and distortion of quantized coefficients based on the Cauchy-based probability density function. |
| FILED | Friday, June 25, 2004 |
| APPL NO | 10/877349 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07415764 | Kang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Capstone Turbine Corporation (Chatsworth, California) |
| INVENTOR(S) | Yungmo Kang (La Canada Flintridge, California); Robert D. McKeirnan, Jr. (Westlake Village, California) |
| ABSTRACT | A construction of recuperator core segments is provided which insures proper assembly of the components of the recuperator core segment, and of a plurality of recuperator core segments. Each recuperator core segment must be constructed so as to prevent nesting of fin folds of the adjacent heat exchanger foils of the recuperator core segment. A plurality of recuperator core segments must be assembled together so as to prevent nesting of adjacent fin folds of adjacent recuperator core segments. |
| FILED | Friday, January 20, 2006 |
| APPL NO | 11/336718 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Metal working 029/890.39 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416258 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Claude B. Reed (Bolingbrook, Illinois); Zhiyue Xu (Naperville, Illinois); Richard A. Parker (Arvada, Colorado); Ramona M. Graves (Evergreen, Colorado); Thomas W. Stone (Hellertown, Pennsylvania) |
| ABSTRACT | Apparatus and methods of using lasers are provided for spalling and drilling holes into rocks. A rock removal process is provided that utilizes a combination of laser-induced thermal stress and laser induced superheated steam explosions just below the surface of the laser/rock interaction to spall the rock into small fragments that can then be easily removed by a purging flow. Single laser beams of given irradiance spall rock and create holes having diameter and depth approximately equal to the beam spot size. A group of the single laser beams are steered in a controllable manner by an electro-optic laser beam switch to locations on the surface of the rock, creating multiple overlapping spalled holes thereby removing a layer of rock of a desired diameter. Drilling of a deep hole is achieved by spalling consecutive layers with an intermittent feed motion of the laser head perpendicular to the rock surface. |
| FILED | Friday, April 14, 2006 |
| APPL NO | 11/404698 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Mining or in situ disintegration of hard material 299/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416598 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Susan Sun (Manhattan, Kansas); Donghai Wang (Manhattan, Kansas); Zhikai Zhong (Manhattan, Kansas); Guang Yang (Shanghai, China PRC) |
| ABSTRACT | The, present invention provides useful adhesive compositions having similar adhesive properties to conventional UF and PPF resins. The compositions generally include a protein portion and modifying ingredient portion selected from the group consisting of carboxyl-containing compounds, aldehyde-containing compounds, epoxy group-containing compounds, and mixtures thereof. The composition is preferably prepared at a pH level at or near the isoelectric point of the protein. In other preferred forms, the adhesive composition includes a protein portion and a carboxyl-containing group portion. |
| FILED | Monday, January 03, 2005 |
| APPL NO | 11/028013 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions: Coating or plastic 16/127.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416844 | Korlach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Monday, November 21, 2005 |
| APPL NO | 11/285422 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417096 | McCormick, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern Mississippi (Hattiesburg, Mississippi) |
| INVENTOR(S) | Charles L. McCormick, III (Hattiesburg, Mississippi); Andrew B. Lowe (Hattiesburg, Mississippi); Brent S. Sumerlin (Pittsburgh, Pennsylvania) |
| ABSTRACT | A new, facile, general one-phase method of generating thiol-functionalized transition metal nanoparticles and surface modified by (co)polymers synthesized by the RAFT method is described. The method includes the steps of forming a (co)polymer in aqueous solution using the RAFT methodology, forming a collidal transition metal precursor solution from an appropriate transition metal; adding the metal precursor solution or surface to the (co)polymer solution, adding a reducing agent into the solution to reduce the metal colloid in situ to produce the stabilized nanoparticles or surface, and isolating the stabilized nanoparticles or surface in a manner such that aggregation is minimized. The functionalized surfaces generated using these methods can further undergo planar surface modifications, such as fuctionalization with a variety of different chemical groups, expanding their utility and application. |
| FILED | Wednesday, October 25, 2006 |
| APPL NO | 11/586126 |
| ART UNIT | 1796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Synthetic resins or natural rubbers 526/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417222 | Pfeifer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Kent B. Pfeifer (Los Lunas, New Mexico); Steven B. Rohde (Corrales, New Mexico) |
| ABSTRACT | Correlation ion mobility spectrometry (CIMS) uses gating modulation and correlation signal processing to improve IMS instrument performance. Closely spaced ion peaks can be resolved by adding discriminating codes to the gate and matched filtering for the received ion current signal, thereby improving sensitivity and resolution of an ion mobility spectrometer. CIMS can be used to improve the signal-to-noise ratio even for transient chemical samples. CIMS is especially advantageous for small geometry IMS drift tubes that can otherwise have poor resolution due to their small size. |
| FILED | Monday, August 15, 2005 |
| APPL NO | 11/204268 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417228 | Belov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Leonidovich Belov (Moscow, Russian Federation); Victor Aleksandrovich Gorodnichev (Moscow, Russian Federation); Valentin Ivanovich Kozintsev (Moscow, Russian Federation); Olga Alekseevna Smimova (Moscow, Russian Federation); Yurii Victorovich Fedotov (Moscow, Russian Federation); Anastasiva Michailovnan Khroustaleva (Moscow, Russian Federation) |
| ABSTRACT | Detection of oil pollution on water surfaces includes providing echo signals obtained from optical radiation of a clean water area at two wavelengths, optically radiating an investigated water area at two wavelengths and obtaining echo signals from the optical radiation of the investigated water area at the two wavelengths, comparing the echo signals obtained from the radiation of the investigated area at two wavelengths with the echo signals obtained from the radiation of the clean water area, and based on the comparison, determining presence or absence of oil pollution in the investigated water area. |
| FILED | Monday, October 30, 2006 |
| APPL NO | 11/554228 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/336.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417730 | Duan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Yixiang Duan (Los Alamos, New Mexico); Wenqing Cao (Los Alamos, New Mexico) |
| ABSTRACT | An apparatus and method for monitoring diabetes through breath acetone detection and quantitation employs a microplasma source in combination with a spectrometer. The microplasma source provides sufficient energy to produce excited acetone fragments from the breath gas that emit light. The emitted light is sent to the spectrometer, which generates an emission spectrum that is used to detect and quantify acetone in the breath gas. |
| FILED | Friday, March 31, 2006 |
| APPL NO | 11/395733 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/316 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417744 | Cooke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Bradly J. Cooke (Jemez Springs, New Mexico); David C. Guenther (Los Alamos, New Mexico) |
| ABSTRACT | An apparatus and corresponding method for coherent hybrid electromagnetic field imaging of a target, where an energy source is used to generate a propagating electromagnetic beam, an electromagnetic beam splitting means to split the beam into two or more coherently matched beams of about equal amplitude, and where the spatial and temporal self-coherence between each two or more coherently matched beams is preserved. Two or more differential modulation means are employed to modulate each two or more coherently matched beams with a time-varying polarization, frequency, phase, and amplitude signal. An electromagnetic beam combining means is used to coherently combine said two or more coherently matched beams into a coherent electromagnetic beam. One or more electromagnetic beam controlling means are used for collimating, guiding, or focusing the coherent electromagnetic beam. One or more apertures are used for transmitting and receiving the coherent electromagnetic beam to and from the target. A receiver is used that is capable of square-law detection of the coherent electromagnetic beam. A waveform generator is used that is capable of generation and control of time-varying polarization, frequency, phase, or amplitude modulation waveforms and sequences. A means of synchronizing time varying waveform is used between the energy source and the receiver. Finally, a means of displaying the images created by the interaction of the coherent electromagnetic beam with target is employed. |
| FILED | Monday, February 27, 2006 |
| APPL NO | 11/363890 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418068 | Barrett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Wayne Melvin Barrett (Rochester, Minnesota); Dong Chen (Croton On Hudson, New York); Paul William Coteus (Yorktwon Heights, New York); Alan Gene Gara (Mount Kisco, New York); Rory Jackson (Eastchester, New York); Gerard Vincent Kopcsay (Yorktown Hieghts, New York); Ben Jesse Nathanson (Teaneck, New York); Paylos Michael Vranas (Bedford Hills, New York); Todd E. Takken (Brewster, New York) |
| ABSTRACT | A data capture technique for high speed signaling to allow for optimal sampling of an asynchronous data stream. This technique allows for extremely high data rates and does not require that a clock be sent with the data as is done in source synchronous systems. The present invention also provides a hardware mechanism for automatically adjusting transmission delays for optimal two-bit simultaneous bi-directional (SiBiDi) signaling. |
| FILED | Monday, February 25, 2002 |
| APPL NO | 10/468992 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/355 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07415876 | Hubbard, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | James E. Hubbard, Jr. (Hampton, Virginia); David K. Pullen (Berwyn Heights, Maryland) |
| ABSTRACT | A pressure sensor includes a pressure sensitive element for sensing a distributed fluid pressure and producing a signal in response. The pressure sensitive element is configured to be mountable on an airfoil or a hydrofoil, for example as a thin film piezoelectric element. The sensor finds applications, for example, in measuring lift or drag on the airfoil or hydrofoil. |
| FILED | Tuesday, November 28, 2006 |
| APPL NO | 11/604994 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/170.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07416062 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Steven M. Arnold (Bath, Ohio); Nicholas Penney (Kent, Ohio) |
| ABSTRACT | A magnetorheological device comprising a housing having a divider within the housing is disclosed and claimed. A rotary impeller having two paddles is rotatably mounted within the housing. The rotary impeller sealingly engages the divider and the paddles in combination with the divider forms a first chamber and a second chamber. Magnetorheological fluid resides in the chambers and a passageway interconnects the first and second chambers. A coil surrounds a portion of the passageway such that when energized the magnetorheological fluid solidifies plugging the passageway. As the impeller rotates, it pushes the incompressible fluid against the divider in the housing and the plug in the passageway and retards and/or stops the motion of the impeller. |
| FILED | Thursday, October 23, 2003 |
| APPL NO | 10/693853 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Brakes 188/267.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07417407 | Stuart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Thomas A. Stuart (Toledo, Ohio); Cyrus N. Ashtiani (West Bloomfield, Michigan) |
| ABSTRACT | A circuit for charging a battery combined with a capacitor includes a power supply adapted to be connected to the capacitor, and the battery. The circuit includes an electronic switch connected to the power supply. The electronic switch is responsive to switch between a conducting state to allow current and a non-conducting state to prevent current flow. The circuit includes a control device connected to the switch and is operable to generate a control signal to continuously switch the electronic switch between the conducting and non-conducting states to charge the battery. |
| FILED | Wednesday, October 12, 2005 |
| APPL NO | 11/249048 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/166 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07416811 | Nakahara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Quallion LLC (Sylmar, California) |
| INVENTOR(S) | Hiroshi Nakahara (Santa Clarita, California); Mikito Nagata (Valencia, California); David M. Skinlo (Valencia, California); Hisashi Tsukamoto (Santa Clarita, California); Hiroyuki Yumoto (Stevenson Ranch, California) |
| ABSTRACT | An electric storage battery and method of manufacture thereof. Active material (78) is removed from both sides of the outer end (88) of the negative electrode (70) in a jellyroll (84) to allow room for adhesive tape (96) to secure the jellyroll. |
| FILED | Wednesday, January 15, 2003 |
| APPL NO | 10/478706 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/94 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07418110 | Lubin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Transpacific Information, LLC (Wilmington, Delaware) |
| INVENTOR(S) | Jeffrey Lubin (Princeton, New Jersey); Michael Anthony Isnardi (Plainsboro, New Jersey); Jeffrey Adam Bloom (West Windsor, New Jersey); Christos Alkiviadis Polyzois (Lawrenceville, New Jersey) |
| ABSTRACT | A method and apparatus for inserting a low frequency watermark into a compressed data stream carrying compressed content is disclosed. A portion of the compressed data stream is decoded to generate decoded content. The decoded content is analyzed to generate watermark insertion information. The compressed content is embedded with a low frequency watermark using the watermark insertion information. |
| FILED | Monday, June 21, 2004 |
| APPL NO | 10/872962 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 07418504 | Larson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | VirnetX, Inc. (Scotts Valley, California) |
| INVENTOR(S) | Victor Larson (Fairfax, Virginia); Robert Dunham Short, III (Leesburg, Virginia); Edmund Colby Munger (Crownsville, Maryland); Michael Williamson (South Riding, Virginia) |
| ABSTRACT | A secure domain name service for a computer network is disclosed that includes a portal connected to a computer network, such as the Internet, and a domain name database connected to the computer network through the portal. The portal authenticates a query for a secure computer network address, and the domain name database stores secure computer network addresses for the computer network. Each secure computer network address is based on a non-standard top-level domain name, such as .scom, .sorg, .snet, .snet, .sedu, .smil and .sint. |
| FILED | Tuesday, November 18, 2003 |
| APPL NO | 10/714849 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07416134 | McDonald |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Glenn E. McDonald (Alexandria, Virginia) |
| ABSTRACT | A system and method of tracking a plurality of items during transfer from a source location to a destination. One embodiment is a method comprising associating information identifying the plurality of items with a radio frequency (RF) tag that identifies a carrier unit. The method further comprises storing the associated information in at least one of the RF tag and a computer memory. The method further comprises communicating with the RE tag to identify the location of the carrier unit. The method further comprises identifying the location of at least one of the plurality of items based at least in part on the location of the carrier unit. Another embodiment is a system configured to perform an embodiment of the method. |
| FILED | Monday, November 21, 2005 |
| APPL NO | 11/284311 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Registers 235/492 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 26, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080826.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page