FedInvent™ Patents
Patent Details for Tuesday, September 23, 2008
This page was updated on Monday, March 27, 2023 at 12:59 AM GMT
Department of Defense (DOD)
| US 07426834 | Granitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Charles Robert Granitz (Loveland, Ohio); Mark Eden Zentgraf (Cincinnati, Ohio) |
| ABSTRACT | A method facilitates assembling a gas turbine engine that includes an oil supply and scavenge system, wherein the oil supply and scavenge system includes at least one sump cavity that includes a first scavenge port and a second scavenge port, a first oil pump and a second oil pump such that the first oil pump is in flow communication with and receives scavenge oil from the first scavenge port and the second oil pump is in flow communication with and receives scavenge oil from the second scavenge port. In addition, an oil supply source is coupled in flow communication with the first and second oil pumps. |
| FILED | Tuesday, February 03, 2004 |
| APPL NO | 10/770783 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/772 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07426859 | Greene et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Archangel Systems, Inc. (Auburn, Alabama) |
| INVENTOR(S) | Michael E. Greene (Opelika, Alabama); Victor S. Trent (Auburn, Alabama) |
| ABSTRACT | A motion sensor may detect linear and/or angular acceleration and/or angular velocity of a body relative to one axis, two orthogonal axes or three orthogonal axes. Movement of the body or reference structure may be detected relative to one or more spinning rotors. The rotor(s) may be suspended for rotation and/or other movement relative to the reference structure without physical contacting the reference structure. In one embodiment, the rotor(s) may be electrostatically suspended in such a way that movement of the rotor(s) relative to the reference structure may be detected. |
| FILED | Friday, October 29, 2004 |
| APPL NO | 10/976459 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427326 | Sumakeris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Joseph J. Sumakeris (Apex, North Carolina); Ranbir Singh (Apex, North Carolina); Michael James Paisley (Garner, North Carolina); Stephan Georg Mueller (Durham, North Carolina); Hudson M. Hobgood (Pittsboro, North Carolina); Calvin H. Carter, Jr. (Cary, North Carolina); Albert Augustus Burk, Jr. (Chapel Hill, North Carolina) |
| ABSTRACT | A method of forming a bipolar device includes forming at least one p-type layer of single crystal silicon carbide and at least one n-type layer of single crystal silicon carbide on a substrate. Stacking faults that grow under forward operation of the device are segregated from at least one of the interfaces between the active region and the remainder of the device. The method of forming bipolar devices includes growing at least one of the epitaxial layers to a thickness greater than the minority carrier diffusion length in that layer. The method also increases the doping concentration of epitaxial layers surrounding the drift region to decrease minority carrier lifetimes therein. |
| FILED | Thursday, November 16, 2006 |
| APPL NO | 11/560575 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427339 | Brengel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Air Products and Chemicals, Inc. (Allentown, Pennsylvania) |
| INVENTOR(S) | David Douglas Brengel (Schnecksville, Pennsylvania); Donald Laurence Meixner (Camarillo, California); Brett Tamatea Henderson (Salt Lake City, Utah) |
| ABSTRACT | The current invention relates to a means for improving heat removal from the inside of an electrochemical device to the outer surface so as to reduce thermal stresses in the device, thereby allowing for increased oxygen production. A means for conducting heat toward the outer edge is provided. The means for conducting heat comprises at least one of silver, gold, platinum, rhodium, and palladium. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/966597 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427359 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Craig B. Arnold (Alexandria, Virginia); Alberto Pique (Crofton, Maryland) |
| ABSTRACT | A method of preparing high capacity hydrous ruthenium oxide micro-ultracapacitors. A laser direct-write process deposits a film of hydrous ruthenium oxide in sulfuric acid under ambient temperature and atmospheric conditions. A dual laser process combining infrared and ultraviolet light is used for fabricating a complete wet electrochemical cell in a single processing step. Ultraviolet laser micromachining is used to tailor the shape and size of the deposited material into planar electrodes. The micro-ultracapacitors have improved size, weight, and cost efficiency and exhibit high specific power and high specific energy. |
| FILED | Wednesday, June 09, 2004 |
| APPL NO | 10/868447 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Etching a substrate: Processes 216/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427394 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of Americas as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); David M. Lynn (Middleton, Wisconsin); Akin Akinc (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided. |
| FILED | Wednesday, May 28, 2003 |
| APPL NO | 10/446444 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427497 | Dordick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, Michigan); Darpa (Arlington, Virginia); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jonathan S. Dordick (Schenectady, New York); Aravind Srinivasan (Cambridge, Massachusetts); Jungbae Kim (Seoul, South Korea); David H. Sherman (Ann Arbor, Michigan); Douglas S. Clark (Orinda, California) |
| ABSTRACT | Disclosed herein is a microfluidics device that can be used to prepare natural products and their analogs. The device comprises the enzymes of a biosynthetic pathway immobilized thereon and a means for sequentially directing a starting material and each ensuing reaction product to the enzymes of the biosynthetic pathway in the order corresponding to the steps of the biosynthetic pathway. The device can thus be used to prepare the natural product using the natural starting material of the biosynthetic pathway or analogs of the natural product using an unnatural starting material. Alternatively, artificial pathways can be created by immobilizing an appropriate selection of enzymes on the device in an order whereby each subsequent enzyme can catalyze a reaction with the product of the prior enzyme. Novel chemical entities can be prepared from these artificial pathways. |
| FILED | Friday, November 01, 2002 |
| APPL NO | 10/287440 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427526 | Fonash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J. Fonash (State College, Pennsylvania); Wook Jun Nam (State College, Pennsylvania); Youngchul Lee (State College, Pennsylvania); Kyuhwan Chang (State College, Pennsylvania); Daniel J. Hayes (State College, Pennsylvania); A. Kaan Kalkan (State College, Pennsylvania); Sanghoon Bae (Cupertino, California) |
| ABSTRACT | This invention uses large surface to volume ratio materials for separation, release layer, and sacrificial material applications. The invention outlines the material concept, application designs, and fabrication methodologies. The invention is demonstrated using deposited column/void network materials as examples of large surface to volume ratio materials. In a number of the specific applications discussed, it is shown that it is advantageous to create structures on a laminate on a mother substrate and then, using the separation layer material approach, to separate this laminate from the mother substrate using the present separation scheme. It is also shown that the present materials have excellent release layer utility. In a number of applications it is also shown how the approach can be used to uniquely form cavities, channels, air-gaps, and related structures in or on various substrates. Further, it is demonstrated that it also can be possible and advantageous to combine the schemes for cavity formation with the scheme for laminate separation. |
| FILED | Tuesday, April 17, 2001 |
| APPL NO | 09/836449 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427679 | Dellinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Agilent Technologies, Inc. (Santa Clara, California) |
| INVENTOR(S) | Douglas J. Dellinger (Boulder, Colorado); Agnieszka B. Sierzchala (Boulder, Colorado); Marvin H. Caruthers (Boulder, Colorado) |
| ABSTRACT | Precursors for use in the synthesis of polynucleotides are disclosed. The precursors include a heterocyclic base having an exocyclic amine group and a substituted or unsubstituted triaryl methyl protecting group bound to the exocyclic amine group. In particular embodiments, the precursor has the structure: wherein: O and H represent oxygen and hydrogen, respectively, R1 is hydrido, hydroxyl, protected hydroxyl, lower alkyl, modified lower alkyl, or alkoxy, one of R2 or R3 is a hydroxyl protecting group; and the other of R2 or R3 is a reactive group capable of reacting with a reactive site hydroxyl, Base is a heterocyclic base having an exocyclic amine group, and Tram is a triaryl methyl group having the structure (V) wherein the broken line represents a bond to the amino nitrogen of the exocyclic amine group, and R4, R5 and R6 are independently selected from unsubstituted or substituted aryl groups, provided that at least one of R4, R5, and R6 is an aryl group other than phenyl and other than substituted phenyl. |
| FILED | Saturday, August 30, 2003 |
| APPL NO | 10/652048 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/26.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427732 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Vicraj T. Thomas (Golden Valley, Indiana); Michael L Rhodes (Richfield, Minnesota); Philip J. Zumsteg (Shorewood, Minnesota); Jan Jelinek (Plymouth, Minnesota) |
| ABSTRACT | A system and method for laser source detection. An exemplary embodiment of the system includes a first array of lenses, a second array of opto devices (including light sources and light detectors), and at least one processor. By positioning the array of lenses to determine the lens position at which energy from an incoming laser is greatest on the light detectors, the approximate location of the laser source may be determined. Upon determining the source, responsive action may be taken. If the incoming laser is from a friendly party, a friendly-party notification may be provided. If the incoming laser is from an enemy, reciprocal targeting or false reflections may be employed. |
| FILED | Thursday, February 22, 2007 |
| APPL NO | 11/678043 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/206.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427758 | Garman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Opto-Knowledge Systems, Inc. (Torrance, California) |
| INVENTOR(S) | John Garman (Los Angeles County, California); Nahum Gat (Los Angeles County, California) |
| ABSTRACT | A thermal infrared camera may be used under a wide variety of target-scene radiation conditions, with interchangeable or zoom lenses requiring matching or different size cold stops. A variable aperture assembly of a thermal infrared camera integrates a rigid open truss-like framework that's capped by an aperture ring and bottomed by a driving ring, and a radiation shield, located inside the framework, that contains an aperture ring at an upper side. A plurality of blades that collectively define an aperture positioned between the upper aperture rings. Opposite blade ends are coupled to respective ones of the two aperture rings, permitting pivotal movement in one ring and radial movement in the other ring, when the rings are rotated relative to one another, to change the size of the formed aperture. Both refractive and reflective infrared telescopes may be retro-fitted with variable aperture devices to enhance infrared imaging performance. |
| FILED | Monday, November 14, 2005 |
| APPL NO | 11/273919 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427867 | Haynes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Intelligent Automation, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Leonard S. Haynes (Rockville, Maryland); Eric van Doom (Frederick, Maryland) |
| ABSTRACT | Method and system for non-destructive evaluation for a conducting structure by measuring the electrical impulse response thereof including applying a PRBS test input signal to the conducting structure, detecting an output signal from the conducting structure and processing the data to assess the condition of the conducting structure via changes in the electrical impulse response and to locate any defects along the conducting structure. |
| FILED | Thursday, May 17, 2007 |
| APPL NO | 11/804252 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/603 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427942 | Catabia |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Derek J. Catabia (South Dartmouth, Massachusetts) |
| ABSTRACT | An apparatus for adaptively generating video signal thresholds for a comparator circuit having a plurality of signal channels. The apparatus has input circuitry in electrical signal communication with the plurality of signal channels. The input circuitry uses a selector circuit to select one signal channel of the plurality of signal channels for processing. The apparatus also has a processing resource having an input joined to process the electrical signals on the selected one signal channel to determine if a video signal is present and, if no video signal is present, to process noise signals on the selected one signal channel to generate a new video signal threshold. The processing resource has an output to provide the new video signal threshold to the comparator circuit corresponding to the selected signal channel. |
| FILED | Monday, February 12, 2007 |
| APPL NO | 11/706682 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427947 | Dark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Dark (Camarillo, California); James Buscemi (Camarillo, California); Scott Burkholder (Moorpark, California) |
| ABSTRACT | The invention generally relates to the field of computer software particularly to an improved method of providing aircrew decision aids for use in determining the optimum placement of an Electronic Attack (EA) aircraft. The core of the invention is a software program that will dynamically provide the EA flight crew situational awareness regarding a threat emitter's coverage relative to the position of the EA aircraft and to the position of protected entities (PE). The software program generates information to provide visual cues representing a Jam Acceptability Region (JAR) contour and a Jam Assessment Strobe (JAS) for display via designated aircraft cockpit processors and devices. The JAR and JAS will aid the EA aircrew in assessing the effectiveness of a given jamming approach. |
| FILED | Wednesday, May 30, 2007 |
| APPL NO | 11/820033 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427948 | Bortnyk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | George P Bortnyk (Seminole, Florida); David J Lupia (Oldsmar, Florida) |
| ABSTRACT | Combining signals includes receiving first signals having a first frequency and second signals having a second frequency. A first weight reflecting a signal-to-noise ratio associated with a first signal is determined for each first signal, and a first signal output is generate from the first signals in accordance with the first weights. A second weight reflecting a signal-to-noise ratio associated with a second signal is determined for each second signal, and a second signal output is generate from the second signals in accordance with the second weights. The first signal output and the second signal output are combined to yield a combined signal output. |
| FILED | Tuesday, July 18, 2006 |
| APPL NO | 11/458348 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428095 | Seitel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven C. Seitel (Ridgecrest, California); Jerome B. Franck (Ridgecrest, California); Marion J. Soileau (Denton, Texas) |
| ABSTRACT | An optical power limiter is designed for use with high gain optical systems by providing intensity reduction by the use of a non-linear fluid. As the intensity of light increases in the fluid, the index of refraction becomes non-linear very rapidly. This results in a plasma being formed within the fluid. Picosecond reaction time is provided. Recovery time of less than a microsecond is required for the system to return to its starting point. |
| FILED | Tuesday, June 01, 1982 |
| APPL NO | 06/385189 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optical: Systems and elements 359/297 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428099 | Javidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Connecticut (Storrs, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Storrs, Connecticut); Ahouzi Esmail (Rabat, Morocco); Guansheng Zhang (Hamilton, Virginia) |
| ABSTRACT | A method of verifying the authenticity of an object is disclosed. The method may include encoding a primary image, convolving the encoded primary image with a random code, generating thereby a first reference image, transforming the first reference image, and correlating the first reference image with a second reference image. |
| FILED | Wednesday, June 14, 2006 |
| APPL NO | 11/424129 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/561 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428106 | Stone |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Thomas W. Stone (Hellertown, Pennsylvania) |
| ABSTRACT | Field flatteners that can correct large field curvatures. |
| FILED | Friday, October 14, 2005 |
| APPL NO | 11/251401 |
| ART UNIT | 2873 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/652 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428252 | Nettleton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | John E. Nettleton (Fairfax Station, Virginia); Dallas N. Barr (Woodbridge, Virginia) |
| ABSTRACT | A monoblock laser cavity includes a plurality of discrete optical components disposed serially on a substrate and sharing a common optical axis. The optical components include a laser rod of gain material, a Q-switch, an OPO crystal, an output coupler, and a positive lens. The output coupler has a convex input end face and a concave output end face, and acts as the expanding lens element of a beam expander, and the positive lens completes the beam expander to improve the beam quality. |
| FILED | Wednesday, March 14, 2007 |
| APPL NO | 11/686348 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428358 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Zhaolin Lu (Newark, Delaware); Dennis W. Prather (Newark, Delaware) |
| ABSTRACT | An optical coupler for parallel coupling from a single mode optical fiber, or fiber ribbon, into a silicon-on-insulator (SOI) waveguide for integration with silicon optoelectronic circuits. The optical coupler incorporates the advantages of the vertically tapered waveguides and prism couplers, yet offers the flexibility of planar integration. The optical coupler may be fabricated using wafer polishing technology or grayscale photolithography. The optical coupler can be packaged using epoxy bonding to form a fiber-waveguide parallel coupler or connector. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 10/597162 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428434 | Tromberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the Univeristy of California (Oakland, California) |
| INVENTOR(S) | Bruce J. Tromberg (Irvine, California); Andrew J. Berger (Rochester, New York); Albert E. Cerussi (Lake Forest, California); Frederic Bevilacqua (Costa Mesa, California); Dorota Jakubowski (Irvine, California) |
| ABSTRACT | A technique for measuring broadband near-infrared absorption spectra of turbid media that uses a combination of frequency-domain and steady-state reflectance methods. Most of the wavelength coverage is provided by a white-light steady-state measurement, whereas the frequency-domain data are acquired at a few selected wavelengths. Coefficients of absorption and reduced scattering derived from the frequency-domain data are used to calibrate the intensity of the steady-state measurements and to determine the reduced scattering coefficient at all wavelengths in the spectral window of interest. The absorption coefficient spectrum is determined by comparing the steady-state reflectance values with the predictions of diffusion theory, wavelength by wavelength. Absorption spectra of a turbid phantom and of human breast tissue in vivo, derived with the combined frequency-domain and steady-state technique, agree well with expected reference values. |
| FILED | Tuesday, July 09, 2002 |
| APPL NO | 10/191693 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428545 | Bala |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | InferX Corporation (McLean, Virginia) |
| INVENTOR(S) | Jerzy Bala (Potomac Falls, Virginia) |
| ABSTRACT | A method and system has an architecture that employs a unique hybrid approach for data mining that integrates advanced three-dimensional computer visualization and inference-based data generalization techniques. The present method and system is geared towards the interactive acquisition and display of visual knowledge representations. Knowledge representations, called knowledge landscapes, are employed for robust real-time classification of incoming data as well as for forecasting new unexpected trends. Knowledge landscape visualization techniques contribute to better human decision-making insights through facilitation of spatial operations such as navigation and zoom operations. A graphically appealing human computer interface and capability to visualize large and complex knowledge bases through spatial and graphical depictions of knowledge components adds to advantages and widespread applicability. |
| FILED | Thursday, July 10, 2003 |
| APPL NO | 10/617054 |
| ART UNIT | 2164 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 07427343 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jongyoon Han (Ithaca, New York); Harold G. Craighead (Ithaca, New York) |
| ABSTRACT | Nanofluidic entropic traps, comprising alternating thin and thick regions, sieve small molecules such as DNA or protein polymers and other molecules. The thick region is comparable or substantially larger than the molecule to be separated, while the thin region is substantially smaller than the size of the molecules to be separated. Due to the molecular size dependence of the entropic trapping effect, separation of molecules may be achieved. In addition, entropic traps are used to collect, trap and control many molecules in the nanofluidic channel. A fabrication method is disclosed to provide an efficient way to make nanofluidic constrictions in any fluidic devices. |
| FILED | Monday, August 25, 2003 |
| APPL NO | 10/648725 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427394 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of Americas as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); David M. Lynn (Middleton, Wisconsin); Akin Akinc (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided. |
| FILED | Wednesday, May 28, 2003 |
| APPL NO | 10/446444 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427472 | Lindsley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Mark D. Lindsley (Lawrenceville, Georgia); Zhenyu Qin (Atlanta, Georgia); Christine J. Morrison (Decatur, Georgia); Jong S. Choi (Daegu, South Korea) |
| ABSTRACT | Methods of detecting a dimorphic fungus, including differentiating a dimorphic fungus from other fungi are disclosed. A sample suspected of containing a nucleic acid of a fungus, such as an internal transcribed spacer-2 (ITS2) nucleic acid sequence of a dimorphic fungal rDNA, is screened for the presence or absence of that nucleic acid. The presence of the nucleic acid indicates the sample was contacted by the fungus. Determining whether the nucleic acid sequence is present in the sample can be accomplished by detecting hybridization between a dimorphic probe, species-specific probe, and/or microbe-specific probe and a nucleic acid sequence corresponding to the ITS2 region of fungal rDNA. Kits and arrays for carrying out these methods also are disclosed. |
| FILED | Wednesday, September 25, 2002 |
| APPL NO | 10/490726 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427476 | Issa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University School of Medicine (Baltimore, Maryland) |
| INVENTOR(S) | Jean-Pierre Issa (Houston, Texas) |
| ABSTRACT | A novel T-type calcium channel (CACNA1G) is provided, as are polynucleotides encoding the same. CACNA1G has been implicated in cellular proliferative disorders. More specifically, it has been observed that the methylation state of specific regions within CpG islands associated with the CACNA1G gene correlates with a number of cancerous phenotypes involving a variety of tissue and cell types. Also provided are methods for detecting cellular proliferative disorders by determining the methylation state of genes or regulatory regions associated therewith, including CACNA1G, as well as kits containing reagents for performing invention methods. |
| FILED | Monday, August 30, 2004 |
| APPL NO | 10/930301 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427485 | Greengard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Paul Greengard (New York, New York); Gilberto Fisone (Stockholm, Sweden) |
| ABSTRACT | The present invention provides a method for identifying an agent to be tested for an ability to treat a psychotic disorder in a patient in need of such treatment. The invention provides a method for screening candidate drugs for anti-psychotic drug activity, preferably atypical anti-psychotic activity, comprising contacting cells or tissues with a candidate drug, determining levels of phosphorylation of the intracellular signaling proteins, DARPP-32, ERK1, ERK2 and CREB, in said cells or tissues and determining the pattern of the levels of phosphorylation of the proteins. The pattern of the levels of phosphorylation of DARPP-32, ERK1, ERK2 and CREB is, in certain embodiments, compared with the pattern of the levels of phosphorylation of DARPP-32, ERK1, ERK2 and CREB in the presence of an atypical anti-psychotic drug. |
| FILED | Tuesday, September 03, 2002 |
| APPL NO | 10/233448 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427486 | Seifer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David B. Seifer (Holmdel, New Jersey); David T. MacLaughlin (Saugus, Massachusetts) |
| ABSTRACT | Methods and kits are provided for assessing the ovarian reserve and predicting the ovarian response to fertility treatments in a female subject. The serum levels of MIS are shown to be positively correlated with the production and retrieval of mature oocytes and serve as prognostic indicators for the female response to fertility treatment. The MIS levels can be monitored prior to and during fertility treatment and are useful to adjust the timing and dosage of treatments in order to produce optimal outcome in individual patients, to avoid ovarian hyperstimulation, or to indicate cancellation of an unsuccessful treatment. MIS can also be administered to women to stimulate follicle development and to prevent depletion of ovarian reserve. |
| FILED | Friday, June 29, 2007 |
| APPL NO | 11/824154 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427488 | Nichols et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Timothy C. Nichols (Chapel Hill, North Carolina); Nadia Malouf (Durham, North Carolina); Elizabeth Merricks (Chapel Hill, North Carolina) |
| ABSTRACT | Isolated and purified platelet voltage dependent calcium channel (VDCC) α1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids, and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC α1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC α1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed. |
| FILED | Tuesday, December 02, 2003 |
| APPL NO | 10/726216 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427489 | Kay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); IRM LLC (Hamilton, Bermuda) |
| INVENTOR(S) | Steve A. Kay (San Diego, California); John B. Hogenesch (Encinitas, California); M. Fernanda Ceriani (Buenos Aires, Argentina); Satchidananda Panda (San Diego, California) |
| ABSTRACT | Screening assays for identifying agents that modulate BK channel activity and further modulate the sleep/wake cycle in a subject, circadian regulated locomotor activity in a subject, or both are provided, as are agents identified using such screening assays. Also provided are methods of modulating the sleep/wake cycle in a subject and methods of modulating circadian regulated locomotor activity in a subject by administering an agent that modulates BK channel activity to the subject, for example, an agent identified by a screening assay as disclosed. |
| FILED | Tuesday, June 17, 2003 |
| APPL NO | 10/464817 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427496 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | John M. Stewart (Denver, Colorado); Daniel C. F. Chan (Denver, Colorado); Lajos Gera (Denver, Colorado); Paul A. Bunn, Jr. (Evergreen, Colorado) |
| ABSTRACT | The invention provides bradykinin antagonists and pharmaceutically acceptable salts thereof having anti-cancer activity. These anti-cancer compounds are particularly useful for inhibiting the growth of lung and prostate cancers. |
| FILED | Wednesday, December 14, 2005 |
| APPL NO | 11/304269 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427497 | Dordick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, Michigan); Darpa (Arlington, Virginia); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jonathan S. Dordick (Schenectady, New York); Aravind Srinivasan (Cambridge, Massachusetts); Jungbae Kim (Seoul, South Korea); David H. Sherman (Ann Arbor, Michigan); Douglas S. Clark (Orinda, California) |
| ABSTRACT | Disclosed herein is a microfluidics device that can be used to prepare natural products and their analogs. The device comprises the enzymes of a biosynthetic pathway immobilized thereon and a means for sequentially directing a starting material and each ensuing reaction product to the enzymes of the biosynthetic pathway in the order corresponding to the steps of the biosynthetic pathway. The device can thus be used to prepare the natural product using the natural starting material of the biosynthetic pathway or analogs of the natural product using an unnatural starting material. Alternatively, artificial pathways can be created by immobilizing an appropriate selection of enzymes on the device in an order whereby each subsequent enzyme can catalyze a reaction with the product of the prior enzyme. Novel chemical entities can be prepared from these artificial pathways. |
| FILED | Friday, November 01, 2002 |
| APPL NO | 10/287440 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427590 | Brenneman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Ramot at Tel-Aviv University, Ltd. (Tel Aviv, Israel) |
| INVENTOR(S) | Douglas E. Brenneman (North Wales, Pennsylvania); Raquel Castellon (Norwalk, California); Catherine Y. Spong (Arlington, Virginia); Janet M. Hauser (Bethesda, Maryland); Illana Gozes (Ramat Hasharon, Israel) |
| ABSTRACT | This invention relates to Activity Dependent Neurotrophic Factor I complex (ADNF I complex) and polypeptides of this complex, which produce their neurotrophic effects through multiple proteases intrinsic to the ADNF I complex. The invention also relates to pharmaceutical compositions comprising ADNF I complex polypeptides, as well as methods for reducing neuronal cell death in vitro and in vivo, methods for treating oxidative stress in a patient, methods for reducing a condition associated with fetal alcohol syndrome in a subject, and methods of enhancing learning and memory both pre- and post-natally, all of which methods use the ADNF I complex polypeptides of the invention. |
| FILED | Thursday, September 12, 2002 |
| APPL NO | 10/489515 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427591 | Ploegh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Brigham and Women's Hospital (Boston, Massachusetts) |
| INVENTOR(S) | Hidde L. Ploegh (Brookline, Massachusetts); Harold A. Chapman (Newton, Massachusetts); Richard J. Riese (Brookline, Massachusetts); Paula R. Bryant (Cambridge, Massachusetts); Matthew S. Bogyo (San Francisco, California) |
| ABSTRACT | Methods and products for suppressing a class II MHC-restricted immune response in a mammal, or in mammalian cells, are described. The methods depend upon inhibiting invariant chain proteolysis by cathepsin S from class II MHC/invariant chain complexes, thereby reducing the competency of class II MHC molecules for binding antigenic peptides, reducing presentation of antigenic peptides by class II MHC molecules, and suppressing immune responses. The methods may be employed in the treatment of autoimmune diseases, allergic responses, and organ or tissue graft rejection. Pharmaceutical and therapeutic compositions which are peptide based inhibitors of cathepsin S are also described. |
| FILED | Thursday, August 05, 2004 |
| APPL NO | 10/913045 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427595 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jing Zhu (Menlo Park, California); Aihao Ding (Riverdale, New York); Carl Nathan (Larchmont, New York) |
| ABSTRACT | The invention is directed to compositions and methods for wound healing and controlling inflammation that involve proepithelin, with or without secretory leukocyte protease inhibitor (SLPI). |
| FILED | Friday, December 12, 2003 |
| APPL NO | 10/735289 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427598 | Spong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of Americas as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Ramot at Tel-Aviv University, Ltd. (Tel Aviv, Israel) |
| INVENTOR(S) | Catherine Y. Spong (Arlington, Virginia); Douglas Brenneman (Lansdale, Pennsylvania); Illana Gozes (Ramat Hasharon, Israel) |
| ABSTRACT | The present invention provides methods for improving performance (e.g. learning and/or memory) using (ADNF) polypeptides, by treating the subject prenatally or postnatally with an Activity Dependent Neurotrophic Factor (ADNF) polypeptide in an amount sufficient to improve postnatal learning and/or memory of the subject. |
| FILED | Thursday, May 31, 2001 |
| APPL NO | 10/296849 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427602 | Shea et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Lonnie D. Shea (Evanston, Illinois); Jeffrey Bonadio (San Diego, California); David J. Mooney (Ann Arbor, Michigan); Martin C. Peters (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed are particular 3-dimensional structural matrices containing nucleic acids, various fabrication processes and methods for the prolonged release of nucleic acids in various biological environments. The nucleic acid-matrix materials are created such that they maintain a defined space, allowing cellular migration, transfection and proliferation to occur in a controlled manner. The fabrication processes provide for both high incorporation efficiencies and control over the sustained nucleic acid release. The resultant nucleic acid-containing structural matrices are thus particularly useful in in vivo cell transfection and gene expression in the context of gene therapy. |
| FILED | Thursday, November 18, 1999 |
| APPL NO | 09/442542 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427606 | Linden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Joel M. Linden (Charlottesville, Virginia); Kenneth Brayman (Charlottesville, Virginia); Gail W. Sullivan (Charlottesville, Virginia) |
| ABSTRACT | The present invention provides a therapeutic method for treating biological diseases that includes the administration of an effective amount of a suitable antibiotic agent, antifungal agent or antiviral agent in conjunction with an A2A adenosine receptor agonist. If no anti-pathogenic agent is known the A2A agonist can be used alone to reduce inflammation, as may occur during infection with antibiotic resistant bacteria, or certain viruses such as those that cause SARS or Ebola. Optionally, the method includes administration of a type IV PDE inhibitor. |
| FILED | Thursday, December 02, 2004 |
| APPL NO | 11/002008 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427608 | Nicotera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York); Health Research, Inc. (Buffalo, New York) |
| INVENTOR(S) | Thomas Nicotera (Buffalo, New York); Donald Henderson (Williamsville, New York); David G. Hangauer, Jr. (Amherst, New York) |
| ABSTRACT | The present invention provides a method for protecting against or treating hearing loss in a subject. This method involves administering an effective amount of a protein tyrosine kinase inhibitor to the subject to protect against or to treat hearing loss. |
| FILED | Friday, March 31, 2006 |
| APPL NO | 11/395937 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/64 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427655 | Frangione et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Blas Frangione (New York, New York); Thomas Wisniewski (Staten Island, New York); Einar M. Sigurdsson (Scarsdale, New York) |
| ABSTRACT | The present invention relates to synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid β which can be used alone or conjugated to an immunostimulatory molecule in an immunizing composition for inducing an immune response to amyloid β peptides and amyloid deposits. |
| FILED | Friday, September 19, 2003 |
| APPL NO | 10/666423 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427671 | Matsui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Toshimitsu Matsui (Rockville, Maryland); Stuart A. Aaronson (Great Falls, Virginia); Jacalyn H. Pierce (Bethesda, Maryland) |
| ABSTRACT | A DNA sequence which encodes a human type α platelet derived growth factor receptor protein which preferentially binds to the AA homodimer and AB heterodimer forms of platelet derived growth factor and also binds the BB homodimer at high affinity, is described. Substantially pure human a platelet derived growth factor receptor protein and methods for recombinantly producing human α platelet derived growth factor receptor protein are also described. |
| FILED | Thursday, May 11, 1995 |
| APPL NO | 08/439095 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/395 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427680 | Tsien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Jianghong Rao (Palo Alto, California) |
| ABSTRACT | Fluorescent substrates for beta-lactamases having the general formula shown above are provided. Z includes a fluorophore or chromophore and includes a group that may link to the lactam-containing group; R1 and R2 are independently selected from H, aliphatic, aromatic, alkyl, and acyl; R4 may be H and lower alkyl; B may be H, physiologically acceptable salts or metal, ester groups, ammonium cations, —CHR5OCO(CH2)nCH3, —CHR5OCOC(CH3)3, acylthiomethyl, acyloxy-alpha-benz, deltabutyrolactonyl, methoxycarbonyloxymethyl, phenyl, methylsulphinylmethyl, beta-morpholinoethyl, dialkylaminoethyl, and dialkylaminocarbonyloxymethyl, in which R5 is selected from the group consisting of H and lower alkyl; n is an integer between 0 and 10, inclusive; and A may be S, O, SO, SO2 or CH2. In embodiments, the beta-lactam ring may be cleaved by a beta-lactamase enzyme effective to free a fluorophore. Methods of assaying beta-lactamase activity and monitoring expression in systems using beta-lactamase as a reporter gene are also disclosed. |
| FILED | Friday, July 02, 2004 |
| APPL NO | 10/884019 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428434 | Tromberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the Univeristy of California (Oakland, California) |
| INVENTOR(S) | Bruce J. Tromberg (Irvine, California); Andrew J. Berger (Rochester, New York); Albert E. Cerussi (Lake Forest, California); Frederic Bevilacqua (Costa Mesa, California); Dorota Jakubowski (Irvine, California) |
| ABSTRACT | A technique for measuring broadband near-infrared absorption spectra of turbid media that uses a combination of frequency-domain and steady-state reflectance methods. Most of the wavelength coverage is provided by a white-light steady-state measurement, whereas the frequency-domain data are acquired at a few selected wavelengths. Coefficients of absorption and reduced scattering derived from the frequency-domain data are used to calibrate the intensity of the steady-state measurements and to determine the reduced scattering coefficient at all wavelengths in the spectral window of interest. The absorption coefficient spectrum is determined by comparing the steady-state reflectance values with the predictions of diffusion theory, wavelength by wavelength. Absorption spectra of a turbid phantom and of human breast tissue in vivo, derived with the combined frequency-domain and steady-state technique, agree well with expected reference values. |
| FILED | Tuesday, July 09, 2002 |
| APPL NO | 10/191693 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07426873 | Kholwadwala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, Minnesota) |
| INVENTOR(S) | Deepesh K. Kholwadwala (Albuquerque, New Mexico); Brandon R. Rohrer (Albuquerque, New Mexico); Barry L. Spletzer (Albuquerque, New Mexico); Paul C. Galambos (Albuquerque, New Mexico); Jason W. Wheeler (Albuquerque, New Mexico); Clinton G. Hobart (Albuquerque, New Mexico); Richard C. Givler (Albuquerque, New Mexico) |
| ABSTRACT | Footwear comprises a sole and a plurality of sealed cavities contained within the sole. The sealed cavities can be incorporated as deformable containers within an elastic medium, comprising the sole. A plurality of micro electro-mechanical system (MEMS) pressure sensors are respectively contained within the sealed cavity plurality, and can be adapted to measure static and dynamic pressure within each of the sealed cavities. The pressure measurements can provide information relating to the contact pressure distribution between the sole of the footwear and the wearer's environment. |
| FILED | Thursday, May 04, 2006 |
| APPL NO | 11/417755 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/818 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427302 | Kravitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (, None) |
| INVENTOR(S) | Stanley H. Kravitz (Placitas, New Mexico); Andrew M. Hecht (Sandia Park, New Mexico); Alan P. Sylwester (Albuquerque, New Mexico); Nelson S. Bell (Albuquerque, New Mexico) |
| ABSTRACT | A compact solid source of hydrogen gas, where the gas is generated by contacting water with micro-disperse particles of sodium borohydride in the presence of a catalyst, such as cobalt or ruthenium. The micro-disperse particles can have a substantially uniform diameter of 1-10 microns, and preferably about 3-5 microns. Ruthenium or cobalt catalytic nanoparticles can be incorporated in the micro-disperse particles of sodium borohydride, which allows a rapid and complete reaction to occur without the problems associated with caking and scaling of the surface by the reactant product sodium metaborate. A closed loop water management system can be used to recycle wastewater from a PEM fuel cell to supply water for reacting with the micro-disperse particles of sodium borohydride in a compact hydrogen gas generator. Capillary forces can wick water from a water reservoir into a packed bed of micro-disperse fuel particles, eliminating the need for using an active pump. |
| FILED | Friday, June 08, 2007 |
| APPL NO | 11/695144 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Physical processes 023/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427680 | Tsien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Jianghong Rao (Palo Alto, California) |
| ABSTRACT | Fluorescent substrates for beta-lactamases having the general formula shown above are provided. Z includes a fluorophore or chromophore and includes a group that may link to the lactam-containing group; R1 and R2 are independently selected from H, aliphatic, aromatic, alkyl, and acyl; R4 may be H and lower alkyl; B may be H, physiologically acceptable salts or metal, ester groups, ammonium cations, —CHR5OCO(CH2)nCH3, —CHR5OCOC(CH3)3, acylthiomethyl, acyloxy-alpha-benz, deltabutyrolactonyl, methoxycarbonyloxymethyl, phenyl, methylsulphinylmethyl, beta-morpholinoethyl, dialkylaminoethyl, and dialkylaminocarbonyloxymethyl, in which R5 is selected from the group consisting of H and lower alkyl; n is an integer between 0 and 10, inclusive; and A may be S, O, SO, SO2 or CH2. In embodiments, the beta-lactam ring may be cleaved by a beta-lactamase enzyme effective to free a fluorophore. Methods of assaying beta-lactamase activity and monitoring expression in systems using beta-lactamase as a reporter gene are also disclosed. |
| FILED | Friday, July 02, 2004 |
| APPL NO | 10/884019 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427755 | Ding et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Haifeng Ding (Nanjing, China PRC); Dongqi Li (Beijing, China PRC); John E. Pearson (Plainfield, Illinois) |
| ABSTRACT | An electron beam heating device with the temperature up to 2200 K is provided for heating a sample and a tip for a scanning tunneling microscope (STM). The electron beam heating device includes a base stage for mating respectively with an electron beam sample heating carrier and an electron beam tip heating carrier, both carriers include a filament. The integration of the filament into the transferable electron beam sample heating carrier and electron beam tip heating carrier enables filament exchange without venting the vacuum system. A fixed distance between the sample and the filament enables reproducible sample temperature control and the filament is mounted at a back of the sample, allowing optical access for temperature measurement, and allowing sample preparation processes without changing positions of the sample or the filament. Once the tip is loaded, a fixed relative position between the tip and the filament enables reproducible control of heating. A tip holder includes an electrically isolated post connected to the tip, enabling a separate electrical potential to be applied to the tip. |
| FILED | Wednesday, May 31, 2006 |
| APPL NO | 11/443714 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/306 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427814 | Bagepalli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Bharat Bagepalli (Niskayuna, New York); Gary R. Barnes (Delanson, New York); Aniruddha D. Gadre (Rexford, New York); Patrick L. Jansen (Scotia, New York); Charles G. Bouchard, Jr. (Schenectady, New York); Emil D. Jarczynski (Scotia, New York); Jivtesh Garg (Cambridge, Massachusetts) |
| ABSTRACT | A wind generator includes: a nacelle; a hub carried by the nacelle and including at least a pair of wind turbine blades; and an electricity producing generator including a stator and a rotor carried by the nacelle. The rotor is connected to the hub and rotatable in response to wind acting on the blades to rotate the rotor relative to the stator to generate electricity. A cooling system is carried by the nacelle and includes at least one ambient air inlet port opening through a surface of the nacelle downstream of the hub and blades, and a duct for flowing air from the inlet port in a generally upstream direction toward the hub and in cooling relation to the stator. |
| FILED | Wednesday, March 22, 2006 |
| APPL NO | 11/385730 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Prime-mover dynamo plants 290/55 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427815 | Ye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Zhihong Ye (Clifton Park, New York); Pengwei Du (Troy, New York) |
| ABSTRACT | A phase shift procedure for detecting a disconnect of a power grid from a feeder that is connected to a load and a distributed generator. The phase shift procedure compares a current phase shift of the output voltage of the distributed generator with a predetermined threshold and if greater, a command is issued for a disconnect of the distributed generator from the feeder. To extend the range of detection, the phase shift procedure is used when a power mismatch between the distributed generator and the load exceeds a threshold and either or both of an under/over frequency procedure and an under/over voltage procedure is used when any power mismatch does not exceed the threshold. |
| FILED | Friday, November 14, 2003 |
| APPL NO | 10/713310 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical transmission or interconnection systems 37/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428434 | Tromberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the Univeristy of California (Oakland, California) |
| INVENTOR(S) | Bruce J. Tromberg (Irvine, California); Andrew J. Berger (Rochester, New York); Albert E. Cerussi (Lake Forest, California); Frederic Bevilacqua (Costa Mesa, California); Dorota Jakubowski (Irvine, California) |
| ABSTRACT | A technique for measuring broadband near-infrared absorption spectra of turbid media that uses a combination of frequency-domain and steady-state reflectance methods. Most of the wavelength coverage is provided by a white-light steady-state measurement, whereas the frequency-domain data are acquired at a few selected wavelengths. Coefficients of absorption and reduced scattering derived from the frequency-domain data are used to calibrate the intensity of the steady-state measurements and to determine the reduced scattering coefficient at all wavelengths in the spectral window of interest. The absorption coefficient spectrum is determined by comparing the steady-state reflectance values with the predictions of diffusion theory, wavelength by wavelength. Absorption spectra of a turbid phantom and of human breast tissue in vivo, derived with the combined frequency-domain and steady-state technique, agree well with expected reference values. |
| FILED | Tuesday, July 09, 2002 |
| APPL NO | 10/191693 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07427394 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of Americas as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); David M. Lynn (Middleton, Wisconsin); Akin Akinc (Newton, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided. |
| FILED | Wednesday, May 28, 2003 |
| APPL NO | 10/446444 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427484 | Keller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nancy P. Keller (Madison, Wisconsin); Jin Woo Bok (Madison, Wisconsin) |
| ABSTRACT | The invention provides polypeptides and nucleic acids which identify and encode LaeA, a regulator of fungal secondary metabolite production which exhibits global control over secondary metabolite biosynthetic gene clusters. The invention further provides expression vectors, host cells, methods of increasing the production of secondary metabolites in an organism naturally producing a secondary metabolite or engineered to produce a secondary metabolite, and methods of identifying novel secondary metabolite biosynthesis gene clusters. |
| FILED | Tuesday, December 20, 2005 |
| APPL NO | 11/314351 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07428099 | Javidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Connecticut (Storrs, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Storrs, Connecticut); Ahouzi Esmail (Rabat, Morocco); Guansheng Zhang (Hamilton, Virginia) |
| ABSTRACT | A method of verifying the authenticity of an object is disclosed. The method may include encoding a primary image, convolving the encoded primary image with a random code, generating thereby a first reference image, transforming the first reference image, and correlating the first reference image with a second reference image. |
| FILED | Wednesday, June 14, 2006 |
| APPL NO | 11/424129 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/561 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07426848 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Jing Li (San Jose, California); Meyya Meyyappan (San Jose, California) |
| ABSTRACT | A method and system for estimating one, two or more unknown components in a gas. A first array of spaced apart carbon nanotubes (“CNTs”) is connected to a variable pulse voltage source at a first end of at least one of the CNTs. A second end of the at least one CNT is provided with a relatively sharp tip and is located at a distance within a selected range of a constant voltage plate. A sequence of voltage pulses {V(tn)}n at times t=tn (n=1, . . . , N1; N1≧3) is applied to the at least one CNT, and a pulse discharge breakdown threshold voltage is estimated for one or more gas components, from an analysis of a curve I(tn) for current or a curve e(tn) for electric charge transported from the at least one CNT to the constant voltage plate. Each estimated pulse discharge breakdown threshold voltage is compared with known threshold voltages for candidate gas components to estimate whether at least one candidate gas component is present in the gas. The procedure can be repeated at higher pulse voltages to estimate a pulse discharge breakdown threshold voltage for a second component present in the gas. |
| FILED | Friday, August 05, 2005 |
| APPL NO | 11/203576 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/23.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07427428 | DiCarlo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | James A. DiCarlo (North Olmsted, Ohio); Ramakrishna Bhatt (North Olmstead, Ohio); Gregory N. Morscher (Stow, Ohio); Hee-Mann Yun (North Olmstead, Ohio) |
| ABSTRACT | A ceramic matrix composite material is disclosed having non-oxide ceramic fibers, which are formed in a complex fiber architecture by conventional textile processes; a thin mechanically weak interphase material, which is coated on the fibers; and a non-oxide or oxide ceramic matrix, which is formed within the interstices of the interphase-coated fiber architecture. During composite fabrication or post treatment, the interphase is allowed to debond from the matrix while still adhering to the fibers, thereby providing enhanced oxidative durability and damage tolerance to the fibers and the composite material. |
| FILED | Tuesday, June 24, 2003 |
| APPL NO | 10/601657 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/376.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07427662 | Hornick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Baord of Supervisors of Louisiana State University And Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Conrad A. Hornick (New Orleans, Louisiana); Eugene A. Woltering (Kenner, Louisiana) |
| ABSTRACT | Apolipoprotein A-I-rich Lhigh-density Lipoprotein 2 (HDL2) and Apolipoprotein A-I (ApoA-I) was discovered to inhibit angiogenesis in an in vitro human angiogenesis model, the human placental vein angiogenesis model. Apolipoprotein A-I was able to destroy a pre-existing angiogenic response as well as prevent the development of new vessels. Application of Apolipoprotein A-I will be effective in inhibiting tumor growth dependent on angiogenesis, and in decreasing existing blood vessels formed by tumors. It will also be effective in treating non-cancerous diseases which symptoms include an increase in angiogenesis, e.g., psoriasis, retinopathy of prematurity, neovascular glaucoma, diabetic retinopathy, obesity, and psoriasis. |
| FILED | Tuesday, February 01, 2005 |
| APPL NO | 11/047852 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/359 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 07428099 | Javidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Connecticut (Storrs, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Storrs, Connecticut); Ahouzi Esmail (Rabat, Morocco); Guansheng Zhang (Hamilton, Virginia) |
| ABSTRACT | A method of verifying the authenticity of an object is disclosed. The method may include encoding a primary image, convolving the encoded primary image with a random code, generating thereby a first reference image, transforming the first reference image, and correlating the first reference image with a second reference image. |
| FILED | Wednesday, June 14, 2006 |
| APPL NO | 11/424129 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/561 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07427758 | Garman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Opto-Knowledge Systems, Inc. (Torrance, California) |
| INVENTOR(S) | John Garman (Los Angeles County, California); Nahum Gat (Los Angeles County, California) |
| ABSTRACT | A thermal infrared camera may be used under a wide variety of target-scene radiation conditions, with interchangeable or zoom lenses requiring matching or different size cold stops. A variable aperture assembly of a thermal infrared camera integrates a rigid open truss-like framework that's capped by an aperture ring and bottomed by a driving ring, and a radiation shield, located inside the framework, that contains an aperture ring at an upper side. A plurality of blades that collectively define an aperture positioned between the upper aperture rings. Opposite blade ends are coupled to respective ones of the two aperture rings, permitting pivotal movement in one ring and radial movement in the other ring, when the rings are rotated relative to one another, to change the size of the formed aperture. Both refractive and reflective infrared telescopes may be retro-fitted with variable aperture devices to enhance infrared imaging performance. |
| FILED | Monday, November 14, 2005 |
| APPL NO | 11/273919 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 23, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20080923.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page