FedInvent™ Patents
Patent Details for Tuesday, October 07, 2008
This page was updated on Monday, March 27, 2023 at 12:59 AM GMT
Department of Defense (DOD)
US 07430866 | Lynch et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | William A. Lynch (Philadelphia, Pennsylvania); Neal A. Sondergaard (Severna Park, Maryland) |
ABSTRACT | A metallic fuel mixture including solidic powders such as silicon, aluminum and magnesium together with an oxidant, and steam and hydrogen are fed into a combustor to undergo combustion therein. The combustor is positioned within a steam chamber enclosure filled with water as working fluid which is heated by the combustion. The heated water within the stream chamber enclosure is thereby converted into pressurized steam fed into a turbine for operation thereof to impart rotation to a shaft thereby propelling a sea vessel within which the steam chamber enclosure is housed. During such combustion, discharge from the combustor of a liquid by-product occurs as outflow through an exhaust funnel into a collector from which the by-product is processed for ejection into seawater without signature detection. The radiant energy generated by such combustion may be converted by photovoltaic cells within the steam chamber enclosure into electrical energy made available outside of the steam chamber enclosure, while some of the heat energy generated by the combustion within the combustor may also be converted by thermoelectric cells into electrical energy made available outside of the steam chamber enclosure. |
FILED | Tuesday, November 08, 2005 |
APPL NO | 11/272424 |
ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
CURRENT CPC | Power plants 060/645 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07430964 | Munsinger et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Terrence Lane Munsinger (Ridgecrest, California); David L. Riggs (Ridgecrest, California) |
ABSTRACT | A safe and arm device and method for a fuze in a bomb utilizing a piston and a drive shaft to rotate a rotor in and out of the safe and armed positions. The piston is operated by a difference in air pressure within the fuze as the bomb leaves its delivery vehicle. |
FILED | Wednesday, August 08, 2007 |
APPL NO | 11/894634 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/229 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431501 | Main |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Richard E. Main (Fredericksburg, Virginia) |
ABSTRACT | An electrostatic discharge (ESD) protective bag assembly includes a tote bag and an envelope made from ESD protective material positioned at least partially within the tote bag. The envelope may be defined by two sheets of ESD protective material joined along at least two opposing sides thereof to form join regions. At least one layer of a reinforcing material, such as a fibrous web, is coupled to a portion of each of the join regions. The tote bag and envelope may be coupled to one another by stitches that pass through the reinforcing material. |
FILED | Monday, November 15, 2004 |
APPL NO | 10/989863 |
ART UNIT | 3782 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Flexible bags 383/107 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431559 | Paauwe et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | Corneil Paauwe (Manchester, Connecticut); Joseph Bridges (Durham, Connecticut); Matthew Devore (Portland, Connecticut) |
ABSTRACT | A vane for use in a gas turbine engine has a leading edge facing an upstream combustor. The vane has hollow areas that receive an impingement tube for delivering impingement air. The impingement tube includes a radially outer portion and a radially inner portion. An end wall of the radially outer portion is angled relative to a rotational axis of the turbine such that air entering the impingement tube from a radially outer source has dirt directed away from the leading edge. Thus, dirt is less likely to clog leading edge air supply holes. In one embodiment, the inner and outer portions are formed as separate pieces, and in another embodiment, the inner and outer portions are formed as a single piece. |
FILED | Tuesday, December 21, 2004 |
APPL NO | 11/018629 |
ART UNIT | 3748 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431832 | Plishker et al. |
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ASSIGNEE(S) | Sam Houston State University (Huntsville, Texas) |
INVENTOR(S) | Gordon Alf Plishker (The Woodlands, Texas); Robert Gavin Jones (Huntsville, Texas); Ralph Edward Holm (Texas City, Texas); Joshua Richard Quinn (Huntsville, Texas) |
ABSTRACT | In some embodiments, a system may reduce contaminants in water. A system may include a biofilm in a container. The biofilm may be formed from one or more bacteria coupled to one or more substrates. The bacteria may be selected to maximize the reduction of contaminants in water. The system may include one or more bacteria generators to provide bacteria to the biofilm and/or one or more air sources to provide an air bubble stream to the container and/or the bacteria generator. In some embodiments, bacteria may be preserved in a starvation phase. Bacteria may be incubated until they reach a starvation phase. The bacteria may then be preserved as beads or immobilized on a substrate. The preserved bacteria may be used in a system for the reduction of contaminants in water. |
FILED | Friday, March 03, 2006 |
APPL NO | 11/368324 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Liquid purification or separation 210/150 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431872 | Dostal et al. |
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ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | David F. Dostal (Cambridge, Wisconsin); Michael P. Wolcott (Moscow, Idaho) |
ABSTRACT | A low-pressure CO2 tank or an air compressor with a refrigerated air dryer is attached to the vent zone of a standard twin-screw extruder. During extrusion, the gas is dissolved in the wood-plastic melt. The CO2 expands which foams the wood-plastic material. |
FILED | Friday, April 26, 2002 |
APPL NO | 10/474992 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/51 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431935 | Singh et al. |
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ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Zhong Zhang (New Bedford, Massachusetts) |
ABSTRACT | The invention features a polypeptide complex synthesized by bacteria of the genus Clostridia that contains the serotype E botulinum neurotoxin and five neurotoxin associated polypeptides having molecular weights of about 118, 80, 65, 40, and 18 kDa. respectively. The complex is useful in the treatment of diseases or conditions that are caused by excessive release of acetylcholine from presynaptic nerve terminals. |
FILED | Tuesday, January 27, 2004 |
APPL NO | 10/766283 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431968 | Shtein et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Max Shtein (Princeton, New Jersey); Stephen R. Forrest (Princeton, New Jersey) |
ABSTRACT | A method of fabricating an organic film is provided. A non-reactive carrier gas is used to transport an organic vapor. The organic vapor is ejected through a nozzle block onto a cooled substrate, to form a patterned organic film. A device for carrying out the method is also provided. The device includes a source of organic vapors, a source of carrier gas and a vacuum chamber. A heated nozzle block attached to the source of organic vapors and the source of carrier gas has at least one nozzle adapted to eject carrier gas and organic vapors onto a cooled substrate disposed within the vacuum chamber. |
FILED | Wednesday, September 04, 2002 |
APPL NO | 10/233470 |
ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Coating processes 427/255.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431970 | Lyuksyutov et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Sergei Lyuksyutov (Akron, Ohio); Shane Juhl (Dayton, Ohio); Richard Vaia (Beavercreek, Ohio) |
ABSTRACT | An atomic force microscopy polymer nanolithography method is described. The method of the present invention enables rapid creation of raised or depressed features in a polymer film. The features are generated by mass transport of polymer within an initially uniform, planar film via localized softening of attoliters of polymer by Joule heating. This localized softening of the polymer is accomplished by current flow between the AFM tip and a conductive wafer upon which the layer of polymer is mounted. |
FILED | Thursday, March 25, 2004 |
APPL NO | 10/817406 |
ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Coating processes 427/256 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432011 | Cardenas-Valencia et al. |
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ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Andres M. Cardenas-Valencia (St. Petersburg, Florida); Robert Frederick Benson (St. Petersburg, Florida); Lawrence C. Langebrake (Seminole, Florida); David P. Fries (St. Petersburg, Florida) |
ABSTRACT | An actuated galvanic cell is described which generated electric current responsive to introduction of electrolyte from a secondary containment means. Also housed within the containment means is a propellant which serves to drive the electrolyte from the containment means into the reaction chamber for electric current production. This propellant system is chosen from thermal, phase change, and other systems which as opposed to physical pumps impel the electrolyte into the reaction chamber without the need for additional introduction apparatus. |
FILED | Friday, December 13, 2002 |
APPL NO | 10/318981 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/70 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432051 | Verma |
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APPLICANT(S) | |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland) |
INVENTOR(S) | Ajay Verma (Bethesda, Maryland) |
ABSTRACT | The present invention relates to the elucidation of the role of erythropoietin and the erythropoietin receptor in the development and progression of certain solid tumors, including those found in breast, cervical, uterine, ovarian, prostate and brain cancer. |
FILED | Friday, November 30, 2001 |
APPL NO | 10/432899 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432092 | Schultz et al. |
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ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California) |
ABSTRACT | Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with keto amino acids using these orthogonal pairs. |
FILED | Wednesday, October 15, 2003 |
APPL NO | 10/530421 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432132 | Rotter et al. |
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ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Shlomo Z. Rotter (Riverside, Ohio); Susan L. Heidger (Kettering, Ohio) |
ABSTRACT | A method of making efficient Integrated Diamond Carrier heat sink and mounting structures usable typically to mount the solid-state laser bars often employed for pumping high power lasers, for example. The disclosed method forms the Integrated Diamond Carrier on a shaped sacrificial substrate member by chemical vapor deposition growing of diamond on a patterned substrate, made from for example silicon semiconductor. The substrate serves as a mold and is etched away after Integrated Diamond Carrier base plate formation leaving the freestanding diamond carrier. Optically usable surfaces are achieved on the Integrated Diamond Carrier through use of substrate crystal plane characteristics and an improved deposition arrangement. |
FILED | Monday, March 28, 2005 |
APPL NO | 11/091685 |
ART UNIT | 2813 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/122 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432161 | Lee et al. |
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ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
ABSTRACT | Methods for forming {110} type facets on a (001) oriented substrate of Group III-V compounds and Group IV semiconductors using selective epitaxial growth is provided. The methods include forming a dielectric film on a (100) substrate. The dielectric film can then be patterned to expose a portion of the substrate and to form a substrate-dielectric film boundary substantially parallel to a <110> direction. A {110} type sidewall facet can then be formed by epitaxially growing a semiconductor layer on the exposed portion of the substrate and the dielectric film. |
FILED | Friday, January 06, 2006 |
APPL NO | 11/326431 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/269 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432175 | Huffaker et al. |
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INVENTOR(S) | Diana L. Huffaker (Albuquerque, New Mexico); Larry R. Dawson (Albuquerque, New Mexico); Ganesh Balakrishnan (Albuquerque, New Mexico) |
ABSTRACT | Lattice mismatched epitaxy and methods for lattice mismatched epitaxy are provided. The method includes providing a growth substrate and forming a plurality of quantum dots, such as, for example, AlSb quantum dots, on the growth substrate. The method further includes forming a crystallographic nucleation layer by growth and coalescence of the plurality of quantum dots, wherein the nucleation layer is essentially free from vertically propagating defects. The method using quantum dots can be used to overcome the restraints of critical thickness in lattice mismatched epitaxy to allow effective integration of various existing substrate technologies with device technologies. |
FILED | Friday, January 06, 2006 |
APPL NO | 11/326432 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/479 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432264 | Jefferson et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Isis Pharmaceuticals, Inc. (Carlsbad, California) |
INVENTOR(S) | Elizabeth Anne Jefferson (La Jolla, California); Eric E. Swayze (Carlsbad, California); Punit P. Seth (San Marcos, California); Dale E. Robinson, Jr. (San Marcos, California) |
ABSTRACT | Provided are antibacterial biaryl compounds having micromolar MIC activity against Gram-negative and Gram-positive pathogens, including a methicillin-resistant S. aureus strain. |
FILED | Monday, August 09, 2004 |
APPL NO | 10/914256 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/249 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432399 | Verborgt et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jozef Verborgt (Clearwater, Florida); Arthur Anthony Webb (Fort Washington, Maryland) |
ABSTRACT | A polyol monomer comprising the formula: R1 and R3 are —H, aliphatic, aromatic, or ether; R2 is aliphatic, aromatic, ester, ether, or acrylic, and R1 contains a hydroxyl group, R3 contains a hydroxyl group, R2 contains —O—CH2—CH(OH)—, or any combination thereof. The polyol monomer may be made by reacting an epoxy and an amine. Either the epoxy contains more than one epoxide groups, the amine contains a hydroxyl group, or both. A thermoset made by reacting the polyol monomer with a polyisocyanate. |
FILED | Tuesday, November 02, 2004 |
APPL NO | 10/979843 |
ART UNIT | 1796 — Organic Chemistry |
CURRENT CPC | Organic compounds 564/305 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432489 | Pileri et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | David Pileri (Newbury Park, California); Harry C. Boretz (Agoura Hills, California); Yan S. Tam (Oak Park, California) |
ABSTRACT | A system and method for errant laser beam detection are provided for effectively detecting small coating failures in a cost effective and robust manner. In one embodiment, a detection system includes a continuity circuit on a printed circuit board (PCB) having metal (e.g., copper) traces which are designed to burn through if an errant beam strikes them. The traces are sized and patterned appropriately to sense a minimum subaperture size. |
FILED | Tuesday, May 31, 2005 |
APPL NO | 11/140890 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Radiant energy 250/205 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432526 | Van de Walle et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Christian G. Van de Walle (Santa Barbara, California); Peter Kiesel (Palo Alto, California); Oliver Schmidt (Palo Alto, California) |
ABSTRACT | A semiconductor device has a heterostructure including a first layer of semiconductor oxide material. A second layer of semiconductor oxide material is formed on the first layer of semiconductor oxide material such that a two dimensional electron gas builds up at an interface between the first and second materials. A passivation layer on the outer surface stabilizes the structure. The device also has a source contact and a drain contact. |
FILED | Tuesday, December 20, 2005 |
APPL NO | 11/314881 |
ART UNIT | 2815 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432634 | Choi et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, University of Texas System (Austin, Texas) |
INVENTOR(S) | Byung-Jin Choi (Austin, Texas); Sidlgata V. Sreenivasan (Austin, Texas); Stephen C. Johnson (Austin, Texas) |
ABSTRACT | An apparatus to control displacement of a body spaced-apart from a surface includes a flexure system having a first flexure member defining a first axis of rotation and a second flexure member defining a second axis of rotation. A body is coupled to the flexure system to move about a plurality of axes. An actuation system is coupled to the flexure system to selectively constrain movement of the body along a subset of the plurality of axes. |
FILED | Monday, February 28, 2005 |
APPL NO | 11/068526 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/323.170 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432821 | Mastro et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Stephen A. Mastro (Glen Mills, Pennsylvania); John K. Overby (Nottingham, Pennsylvania) |
ABSTRACT | A propeller shaft is supported on the stern end of a ship hull by a bearing within which optic fiber cables are embedded in close spaced relation to the outer cylindrical surface of a bearing supported portion of the propeller shaft for a monitoring wear thereof with maximum accuracy. An optical data acquisition system having a light source and a graphic display is operatively connected to the optic fiber cables through inserted optic connector cables to transmit light from the light source as a signal medium into the bearing so as to render the optic fiber cables therein operative as sensors to detect and measure wear of the entire bearing portion of the propeller shaft surface being thereby monitored. Wear measurement optical signals within the wear sensing cables are then transmitted back to the data acquisition system through the optic connector cables for display of the shaft bearing wear measurements. |
FILED | Tuesday, November 01, 2005 |
APPL NO | 11/268402 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/682 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432868 | Webb et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Spencer Webb (Pelham, New Hampshire); David Martin (Nashua, New Hampshire) |
ABSTRACT | A low power, lightweight, collapsible and rugged antenna positioner for use in communicating with geostationary, geosynchronous and low earth orbit satellite. By collapsing, invention may be easily carried or shipped in a compact container. May be used in remote locations with simple or automated setup and orientation. Azimuth is adjusted by rotating an antenna in relation to a positioner base and elevation is adjusted by rotating an elevation motor coupled with the antenna. Manual orientation of antenna for linear polarized satellites yields lower weight and power usage. Updates ephemeris or TLE data via satellite. Algorithms used for search including Clarke Belt fallback, transponder/beacon searching switch, azimuth priority searching and tracking including uneven re-peak scheduling yield lower power usage. Orientation aid via user interface allows for smaller azimuth motor, simplifies wiring and lowers weight. Tilt compensation, bump detection and failure contingency provide robustness. |
FILED | Wednesday, April 26, 2006 |
APPL NO | 11/412720 |
ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Radio wave antennas 343/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432871 | Milroy et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | William W. Milroy (Torrance, California); Stuart B. Coppedge (Manhattan Beach, California); Alec Ekmekji (Los Angeles, California); Shahrokh Hashemi-Yeganeh (Rancho Palos Verdes, California); Steven G. Buczek (Brea, California) |
ABSTRACT | A true-time-delay feed network for a continuous transverse stub antenna array includes a plurality of feed levels, each comprising one or more rails, the feed levels arranged in a spaced configuration. An open parallel plate region is defined between adjacent ones of the feed levels. The rails of the plurality of feed levels are arranged to form a power divider network unencumbered with septums or wall portions protruding into the open region. |
FILED | Tuesday, March 08, 2005 |
APPL NO | 11/075106 |
ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Radio wave antennas 343/776 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433043 | Birge et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Jonathan R. Birge (Cambridge, Massachusetts); Richard Ell (Belmont, Massachusetts); Franz X. Kaertner (Newton, Massachusetts) |
ABSTRACT | The phase spectrum of an ultrashort pulse is measured based on two-dimensional spectral shearing interferometry with zero delay. The measurement is performed utilizing an optical source pulse from which is extracted a short pulse and from which a chirped component is generated. The chirped component is split into first and second chirped pulses. The first and second pulses are then mixed with the short pulse in a nonlinear medium to produce up-converted and spectrally sheared copies of the first and second chirped pulses, which are measured in a spectrometer. A plurality of path lengths for the first second chirped pulses is provided to shift the relative phases of the first and second chirped pulses for additional measurements. The apparatus and methods are uniquely suited for characterizing single-cycle pulses. |
FILED | Friday, December 08, 2006 |
APPL NO | 11/608683 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/450 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433044 | Szarmes et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Hawaii (Honolulu, Hawaii) |
INVENTOR(S) | Eric Szarmes (Honolulu, Hawaii); Huan Ma (Honolulu, Hawaii) |
ABSTRACT | A Fourier transform spectrometer based on a modified Sagnac interferometer is described. The instrument uses one or more gratings as dispersive elements to greatly improve the spectral resolution, and in-line optics to match the beam size in the interferometer to optimize the efficiency. The resolution can approach about 0.6 GHz at about 632.8 nm (λ/Δλ=8.4×105). A CCD or photodiode array is used as the detector and the fast Fourier transform of the fringe pattern is performed by a computer. Some embodiments employ no mechanically moving parts; therefore, they are compact and easy to align. Practical applications include remote sensing, process monitoring, and basic research. The fast response time of the detector also allows real time spectral analysis. |
FILED | Friday, June 03, 2005 |
APPL NO | 11/145164 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/451 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433266 | Lédeczi et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Ákos Lédeczi (Nashville, Tennessee); Miklós Maróti (Szeged, Hungary); Gyula Simon (Nashville, Tennessee); György Balogh (Nashville, Tennessee) |
ABSTRACT | A system for locating an acoustic source from an acoustic event of the acoustic source. In one embodiment, the system includes a sensor network having a plurality of spatially separated sensor nodes each located in a predetermined position encountering acoustic waves generated by an acoustic event passing proximate to the plurality of spatially separated sensor nodes, where the plurality of spatially separated sensor nodes are synchronized to a common time base such that when the acoustic event is detected, information of the acoustic waves from each of the plurality of spatially separated sensor nodes is obtained and broadcasted through the sensor network. The system further includes a base station for receiving information of the acoustic waves broadcasted from the sensor network and processing the received information of the acoustic waves so as to locate the acoustic source of the acoustic event. |
FILED | Thursday, September 15, 2005 |
APPL NO | 11/227446 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/129 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433363 | Rosen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Warren Rosen (Rydal, Pennsylvania); Satyen Sukhtankar (Philadelphia, Pennsylvania); Ralph N. Lachenmaier (Ridgecrest, California) |
ABSTRACT | A low latency switch architecture for high performance packet-switched networks which is a combination of input buffers capable of avoiding head-of-line blocking and an internal switch interconnect capable of allowing different input ports to access a single output simultaneously. |
FILED | Wednesday, January 12, 2005 |
APPL NO | 11/040298 |
ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Multiplex communications 370/413 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433434 | Gifford et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | General Dynamics C4 Systems, Inc. (Scottsdale, Arizona) |
INVENTOR(S) | Carl Steven Gifford (Gilbert, Arizona); John Eric Kleider (Atlanta, Georgia); Chad Scott Bergstrom (Chandler, Arizona); Jeffery Scott Chuprun (Scottsdale, Arizona); Bruce Alan Fette (Mesa, Arizona) |
ABSTRACT | Apparatus are provided for a communication signal processing apparatus having a channel estimator configured to generate a first channel estimation at a first time point, a linear predictor coupled to the channel estimator, and an adaptive filter coupled with the linear predictor. The linear predictor is configured to predict a second channel estimation based on a second time point and a channel frequency. The second time point is concurrent or subsequent to the first time point. The second channel estimation includes a first coefficient. The linear predictor includes a first predictor having a sample time point. The first predictor is configured to generate the first coefficient of the second channel estimation based on the sample time point and the second time point. The sample time point is prior to the second time point. The adaptive filter is configured to recursively determine the second channel estimation. |
FILED | Friday, October 01, 2004 |
APPL NO | 10/956658 |
ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Pulse or digital communications 375/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433596 | Harres |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Boeing Corporation (Chicago, Illinois) |
INVENTOR(S) | Daniel N. Harres (Belleville, Illinois) |
ABSTRACT | An apparatus is provided that is capable of achieving bidirectional, full-duplex communication with an optical transceiver. In some instances, the communication is achieved over a single electrical connection of the transceiver and via the use of a duplexing circuit on the transceiver and a complementary duplexing circuit on a distal circuit coupled to the transceiver via the single electrical connection. The techniques described may be used to modify existing optical transceivers to provide diagnostic or health information without interrupting normal transceiver operation. |
FILED | Friday, December 23, 2005 |
APPL NO | 11/317766 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Optical communications 398/41 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433806 | Berk et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Spectral Sciences, Inc. (Burlington, Massachusetts) |
INVENTOR(S) | Alexander Berk (Sharon, Massachusetts); Prabhat K. Acharya (Burlington, Massachusetts); Lawrence S. Bernstein (Lexington, Massachusetts); Gail P. Anderson (Boulder, Colorado); Paul Lewis (Falls Church, Virginia); James H. Chetwynd (Stoneham, Massachusetts); Michael L. Hoke (Leominster, Massachusetts) |
ABSTRACT | A radiative transport band model algorithm has been developed for prediction and analysis of high spectral resolution radiometric measurements. Atomic and molecular line center absorption is determined from finite spectral bin equivalent widths. A new mathematically exact expansion for finite bin equivalent widths provides high accuracy at any desired spectral resolution. The temperature and pressure dependent Voigt line tail spectral absorption contributing to each spectral bin is pre-computed and fit to Padé approximants for rapid and accurate accounting of neighboring-to-distant lines. |
FILED | Friday, April 20, 2001 |
APPL NO | 09/838801 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US H2224 | Madden |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Thomas L. Madden (Dayton, Ohio) |
ABSTRACT | A method to passively locate an emitter using two aircraft to form a large baseline interferometer. The basic two element (two aircraft or helicopters) large baseline interferometer includes self-calibration and allows for various configurations for geo-location of ground-based emitters. The two aircraft large baseline interferometer can measure phase difference of arrival (PDOA) to very precisely locate the emitter in angle. Moving emitters can also be located and tracked using the method of the invention with greater accuracy than can be achieved from a single platform. |
FILED | Friday, October 14, 2005 |
APPL NO | 11/251003 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/424 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 07431915 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (La Jolla, California) |
INVENTOR(S) | Tao Jiang (San Diego, California); Roger Y. Tsien (La Jolla, California) |
ABSTRACT | A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. Cleavage of X allows separation of A from B, unmasking the normal ability of the basic amino acids in B to drag cargo C into cells near the cleavage event. X is cleaved extracellularly, preferably under physiological conditions. D-amino acids are preferred for the A and B portions, to minimize immunogenicity and nonspecific cleavage by background peptidases or proteases. |
FILED | Friday, October 31, 2003 |
APPL NO | 10/699562 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431926 | Harris et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Rockvill, Maryland) |
INVENTOR(S) | Curtis C. Harris (Garrett Park, Maryland); Makoto Nagashima (Bethesda, Maryland) |
ABSTRACT | The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins. |
FILED | Monday, June 14, 2004 |
APPL NO | 10/868270 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/138.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431931 | Kapikian et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Albert Z. Kapikian (Rockville, Maryland); Robert Chanock (Bethesda, Maryland); Timo Vesikari (Tampere, Finland) |
ABSTRACT | The present invention provides compositions for making a medicament and methods for the administration of a vaccine compositions for protection against human rotaviral disease without significant reactogenicity. Human x rhesus reassortant rotavirus compositions were made which when administered during the first 7 to about 10 days of life, provided a composition which was non-reactogenic followed by booster immunizations at 16 to 18 weeks or 14 to 20 weeks, up to 1 year of age. The immune response induced by the initial neonatal administration of the live rotavirus vaccine composition protects the infant from the reactogenicity of the composition when administered as a second vaccine dose at or after 2 months of age. Administration of the immunogenic composition also is expected to ablate or significantly diminish the increase in the excess of intussusception observed 3 to 7 days following administration of the initial dose of rotavirus vaccine at about 2 to 4 months. |
FILED | Friday, January 26, 2001 |
APPL NO | 10/181908 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/215.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431934 | Koelle et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | David M. Koelle (Seattle, Washington); Zhi Liu (Seattle, Washington); Lawrence Corey (Mercer Island, Washington) |
ABSTRACT | Described is a method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are specific to a virus that attacks skin. Also provided are HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection that have been identified via the methods of the invention. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection. |
FILED | Tuesday, February 28, 2006 |
APPL NO | 11/364438 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/229.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431989 | Sakhrani et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | TriboFilm Research, Inc. (Raleigh, North Carolina) |
INVENTOR(S) | Vinay G. Sakhrani (Raleigh, North Carolina); Joel L. Williams (Cary, North Carolina); Charles Tomasino (Raleigh, North Carolina); Paul M. Vernon, Jr. (Chapel Hill, North Carolina) |
ABSTRACT | A method for preparing one or more lubricated surfaces of an article to reduce the break-out force and sliding frictional force. A lubricant is applied to one or more surfaces, and the lubricant-coated surface is treated by exposing the surface to an energy source, wherein the energy source is an ionizing gas plasma at about atmospheric pressure, gamma radiation, or electron beam radiation. One or more of the surfaces may be exposed to the ionizing gas plasma at about atmospheric pressure prior to application of the lubricant. Another aspect of the invention is articles produced using one or more methods of the invention. |
FILED | Tuesday, March 02, 2004 |
APPL NO | 10/791542 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/411.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432045 | Brandt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
ABSTRACT | This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and non-enveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections. |
FILED | Wednesday, December 01, 2004 |
APPL NO | 11/001674 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432048 | Neri et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Third Wave Technologies, Inc. (Madison, Wisconsin) |
INVENTOR(S) | Bruce P. Neri (Madison, Wisconsin); Jeff G. Hall (Madison, Wisconsin); Victor Lyamichev (Madison, Wisconsin); Lloyd M. Smith (Madison, Wisconsin) |
ABSTRACT | The present invention relates to compositions and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for forming a nucleic acid cleavage structure on a solid support and cleaving the nucleic acid cleavage structure in a site-specific manner. For example, in some embodiments, a 5′ nuclease activity from any of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. |
FILED | Friday, December 08, 2000 |
APPL NO | 09/732622 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432051 | Verma |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland) |
INVENTOR(S) | Ajay Verma (Bethesda, Maryland) |
ABSTRACT | The present invention relates to the elucidation of the role of erythropoietin and the erythropoietin receptor in the development and progression of certain solid tumors, including those found in breast, cervical, uterine, ovarian, prostate and brain cancer. |
FILED | Friday, November 30, 2001 |
APPL NO | 10/432899 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432052 | Warren et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Rockfeller University (New York, New York); Duke University (Durham, North Carolina); Emory University (Atlanta, Georgia) |
INVENTOR(S) | Stephen T. Warren (Atlanta, Georgia); Victoria Brown-Kennerly (Decatur, Georgia); Peng Jin (Marietta, Georgia); Stephanie Ceman (Atlanta, Georgia); Robert B. Darnell (Pelham, New York); Jennifer C. Darnell (Pelham, New York); Jack D. Keene (Durham, North Carolina); Scott A. Tenenbaum (Albany, New York) |
ABSTRACT | Compositions and methods for identifying and/or modulating RNA transcripts and/or genes involved in fragile X syndrome and other associated disorders are provided. In particular, RNA targets for fragile X mental retardation protein (FMRP) have been identified by a novel monoclonal antibody to FMRP and a consensus sequence for the RNA binding region has been identified. Arrays for identifying compounds, proteins, nucleotides, and the like that modulate the RNA targets or associated genes are provided. Additionally, methods for modulating RNA targets are provided. |
FILED | Friday, November 15, 2002 |
APPL NO | 10/495728 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432059 | Freeman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Genetics Institute, LLC (Cambridge, Massachusetts); Brigham and Women's Hospital (Boston, Massachusetts) |
INVENTOR(S) | Gordon Freeman (Brookline, Massachusetts); Irene Chernova (Brighton, Massachusetts); Tatyana Chernova (Mobile, Alabama); Nelly Malenkovich (Boston, Massachusetts); Clive Wood (Boston, Massachusetts); Yvette Latchman (Brookline, Massachusetts); Arlene H. Sharpe (Brookline, Massachusetts) |
ABSTRACT | The invention provides isolated nucleic acids molecules, designated PD-L2 nucleic acid molecules, which encode novel B7-related molecules which are ligands for PD-1. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PD-L2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PD-L2 gene has been introduced or disrupted. The invention further provides isolated PD-L2 polypeptides, fusion proteins, antigenic peptides and anti-PD-L2 antibodies. The invention still further provides methods for promoting or inhibiting the interaction between PD-L2 and PD-1. The invention further provides methods of identifying compounds that upmodulate T cell activation in the presence of a PD-1-mediated signal. Diagnostic and treatment methods utilizing compositions of the invention are also provided. |
FILED | Thursday, June 28, 2001 |
APPL NO | 09/895837 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432060 | Lee |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Richard T. Lee (Weston, Massachusetts) |
ABSTRACT | This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure. |
FILED | Thursday, November 08, 2001 |
APPL NO | 10/024607 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432067 | Nelson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services and The National Institutes of Health (Washington, District of Columbia) |
INVENTOR(S) | Lawrence M. Nelson (Burke, Virginia); Zhi-Bin Tong (Potomac, Maryland) |
ABSTRACT | Disclosed herein are novel nucleic acid and protein sequences that are essential to fertility. In particular, human Mater cDNA and protein sequences are provided. Functional MATER is required for female fertility; zygotes that arise from Mater null oocytes do not progress beyond the two-cell stage. Methods are described for detecting an autoimmune response to MATER in a subject by detecting autoantibodies that recognize an epitope of a MATER protein. Also provided are methods for diagnosis of infertility or reduced fertility by detecting presence of MATER protein autoantibodies in a subject. The disclosure also describes kits for detecting MATER autoantibodies comprising MATER protein. |
FILED | Tuesday, October 24, 2006 |
APPL NO | 11/586075 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432081 | Walker et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
INVENTOR(S) | David H. Walker (Galveston, Texas); Jere W. McBride (League City, Texas) |
ABSTRACT | Novel genes encoding homologous immunoreactive thio-disulfide oxidoreductases, or disulfide bond formation (Dsb) proteins from Ehrlichia chaffeensis and Ehrlichia canis are disclosed. While the E. chaffeensis and E. canis Dsb proteins are at most only 31% or less homologous to other known Dsb proteins, the Ehrlichia Dsbs contain a cysteine active site, Cys-Gly-Tyr-Cys, similar to those in known Dsb proteins. As predicted by 15-amino acid identical N-terminal signal peptides, the proteins are primarily localized in the periplasm of E. chaffeensis and E. canis, possibly playing a role in antigenicity and pathogenesis. The present invention provides the nucleotide and amino acid sequences and expression vectors for the E. chaffeensis and E. canis dsb genes, antisera directed against the proteins, and kits to determine whether an individual or animal is infected with a given species of Ehrlichia. |
FILED | Friday, November 01, 2002 |
APPL NO | 10/286516 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432092 | Schultz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California) |
ABSTRACT | Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with keto amino acids using these orthogonal pairs. |
FILED | Wednesday, October 15, 2003 |
APPL NO | 10/530421 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432093 | Shi |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Yigong Shi (Plainsboro, New Jersey) |
ABSTRACT | The structure of a soluble, functional fragment of human Apaf-1 protein having ADP bound thereto is disclosed. The invention includes such soluble, functional fragments of human Apaf-1 and other metazoan Apaf-1 homologs. Also included in the invention are methods of making such fragments and methods of using them, for example in screening methods to identify adenine nucleotide analogs and other compounds useful for alleviating or preventing disease conditions associated with inappropriate regulation of apoptosis. |
FILED | Friday, January 28, 2005 |
APPL NO | 11/045540 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432236 | Tosato et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland) |
INVENTOR(S) | Giovanna Tosato (Bethesda, Maryland); Sandra E. Pike (North Bethesda, Maryland); Lei Yao (Rockville, Maryland) |
ABSTRACT | Specific fragments of vasostatin are disclosed. Also disclosed is a method of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation using these fragments. A method of stimulating the proliferation or survival of a hematopoietic cell is also disclosed. In one embodiment, the method is disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor. |
FILED | Tuesday, April 01, 2003 |
APPL NO | 10/405588 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432238 | Kisiel et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Walter Kisiel (Albuquerque, New Mexico); Hitendra S. Chand (Albuquerque, New Mexico) |
ABSTRACT | A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2). |
FILED | Friday, April 15, 2005 |
APPL NO | 11/107643 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432242 | Mosberg et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Henry I. Mosberg (Ann Arbor, Michigan); Richard R. Neubig (Ann Arbor, Michigan); Yafei Jin (Dallas, Texas); Hauiling Zhong (Lake Hiawatha, New Jersey); Roger Sunahara (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to novel inhibitors of G-protein signaling. In particular, the present invention provides peptide inhibitors of G protein signaling proteins and methods of using such inhibitors to modulate physiological effects of G protein signaling. The present invention thus provides novel drug targets for a variety of pathologies mediated by defects in G-protein signaling. |
FILED | Thursday, February 13, 2003 |
APPL NO | 10/365840 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432243 | Levin |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Eugene G. Levin (San Diego, California) |
ABSTRACT | The invention relates to fragments of an amino acid sequence of mature, full length 24 kDa fibroblast growth factor-2 or an analog thereof. The fragments have an activity that inhibits the migration of cultured cells as well as inhibiting angiogenesis, tumor growth, or any other processes that involve the migration of cells in vivo. This fragment does not stimulate the proliferation of cells which is in contrast to activity shown by the mature, full-length 24 kDa fibroblast growth factor-2. The present invention also relates to a DNA molecule encoding the fragment, an expression vector and a transformed host containing the DNA molecule, and a method of producing the protein by culturing the transformed host. Moreover, the present invention relates to a therapeutic composition the 24 kDa fibroblast growth factor fragment and a pharmaceutically acceptable carrier. |
FILED | Monday, April 07, 2003 |
APPL NO | 10/408415 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432246 | Schramm et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York); The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Vern L. Schramm (New Rochelle, New York); Jef D. Boeke (Baltimore, Maryland); Anthony Sauvé (Bronx, New York); Ivana Celic (Baltimore, Maryland) |
ABSTRACT | A novel compound, 2′/3′-O-acetyl-ADP-ribose, is provided. The compound is a mixture of the 2′ and 3′ regioisomers of O-acetyl-ADP ribose, and is formed nonenzymatically from 2′-O-acetyl-ADP-ribose, which is the newly discovered product of the reaction of Sir2 enzymes with acetylated peptides and NAD+. Analogs of 2′/3′-O-acetyl-ADP-ribose are also provided. Additionally, methods of preparing 2′/3′-O-acetyl-ADP-ribose, methods of determining whether a test compound is an inhibitor of a Sir2 enzyme, methods of detecting Sir2 activity in a composition, methods of deacetylating an acetylated peptide, and methods of inhibiting the deacetylation of an acetylated peptide are provided. Prodrugs of 2′/3′-O-acetyl-ADP-ribose are also provided. |
FILED | Wednesday, October 12, 2005 |
APPL NO | 11/248523 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/23 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432264 | Jefferson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Isis Pharmaceuticals, Inc. (Carlsbad, California) |
INVENTOR(S) | Elizabeth Anne Jefferson (La Jolla, California); Eric E. Swayze (Carlsbad, California); Punit P. Seth (San Marcos, California); Dale E. Robinson, Jr. (San Marcos, California) |
ABSTRACT | Provided are antibacterial biaryl compounds having micromolar MIC activity against Gram-negative and Gram-positive pathogens, including a methicillin-resistant S. aureus strain. |
FILED | Monday, August 09, 2004 |
APPL NO | 10/914256 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/249 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432301 | Gaston et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); University of Louisville Research Foundation (Louisville, Kentucky) |
INVENTOR(S) | Benjamin M. Gaston (Charlottesville, Virginia); David Gozal (Louisville, Kentucky) |
ABSTRACT | The present invention is directed to a method of treating disordered control of breathing including the treatment of apnea and hypoventilation associated with congenital or acquired brain stem abnormalities. Specifically the invention is directed to treating disordered control of breathing by administering an S-nitrosylating agent selected from the group consisting of ethyl nitrite, glutathione, nitric oxide, S-nitrosocysteine, S-nitrosoglutathione, S-nitro-N-acetyl cysteine. As shown in FIG. 1C the ability of endogenous SNOg to increase VE in freely behaving, conscious rates using whole-body plethysmography revealed that CSNO, GSNO and CGSNO (1 nmol each) caused equivalent increases in VE, whereas D-CSNO had no effect (left bar graph is the equivalent increases in VE, whereas D-CSNO had no effect (left bar graph is the control whereas the right bar represents administration of the respective SNO). |
FILED | Monday, August 12, 2002 |
APPL NO | 10/487060 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/579 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432342 | Braun et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sequenom, Inc. (San Diego, California); The Regents of the University of Califonia (Oakland, California) |
INVENTOR(S) | Andreas Braun (San Diego, California); Charles R. Cantor (Del Mar, California); Stefan M. Kammerer (San Diego, California); Susan Taylor (Del Mar, California); Lora Burns-Hamuro (Somerset, New Jersey); Charles Cook (Mendham, New Jersey); Gary Olson (Moutainside, New Jersey); Christopher Self (West Caldwell, New Jersey) |
ABSTRACT | A-kinase anchor protein (AKAPs) muteins, peptides thereof, and nucleic acids encoding the peptides are provided herein. Also provided are transgenic animals, cells comprising transgenes and various methods employing such peptides. |
FILED | Thursday, May 01, 2003 |
APPL NO | 10/428254 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432349 | Harris et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Curtis C. Harris (Garrett Park, Maryland); Remy Pedeux (Chevy Chase, Maryland); Makoto Nagashima (Sakura, Japan); Masayuki Shiseki (Tokyo, Japan) |
ABSTRACT | This disclosure provides a novel tumor suppressor, referred to as p28ING5, nucleic acid molecules encoding this protein, and methods of making and using these molecules. Also provided are methods of ameliorating, treating, detecting, prognosing, and diagnosing diseases and conditions associated with abnormal p28ING5 expression, such as neoplasia. Kits are also provided. |
FILED | Thursday, January 23, 2003 |
APPL NO | 10/502431 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432351 | Chen |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Lieping Chen (Rochester, Minnesota) |
ABSTRACT | Variant costimulatory polypeptides, nucleic acids encoding such polypeptides, and methods for using the polypeptides and nucleic acids to enhance a T cell response are provided herein. |
FILED | Monday, October 06, 2003 |
APPL NO | 10/679775 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432355 | Weisgraber et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
INVENTOR(S) | Karl H. Weisgraber (Walnut Creek, California); Julie A. Morrow (Oakland, California) |
ABSTRACT | The present invention provides isolated apolipoprotein E (apoE) stable folding intermediates. The invention further provides methods for identifying compounds that alter the structure or level or activity of an apoE stable folding intermediate, as well as methods of inhibiting the formation or activity of stable folding intermediates of apoE. The invention further provides methods for reducing the level and/or activity of an apoE stable folding intermediate, and methods for treating disorders relating to apoE4 in a subject. |
FILED | Wednesday, July 23, 2003 |
APPL NO | 10/626415 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/359 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432365 | O'Donnell et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Michael E. O'Donnell (Hasting-on-Hudson, New York); Irina Bruck (New York, New York); Dan Zhang (Forest Hills, New York); Richard Whipple (Rareton, New Jersey) |
ABSTRACT | The present invention relates to beta protein-encoding genes from Gram positive bacterium. Expression systems and host cells containing these genes are also disclosed. |
FILED | Friday, July 28, 2000 |
APPL NO | 10/048071 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432376 | Davies |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Research Foundation of State University of New York, The (Amherst, New York) |
INVENTOR(S) | Huw M. L. Davies (E. Amherst, New York) |
ABSTRACT | Disclosed are tropane-based prodrug compounds bearing fatty ester and aromatic substituents. The compounds can be used for alleviating symptoms of CNS disorders. |
FILED | Monday, March 12, 2007 |
APPL NO | 11/716817 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/124 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432706 | van der Kouwe |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Andre van der Kouwe (Woburn, Massachusetts) |
ABSTRACT | An fMRI study is conducted using a 2D EPI pulse sequence. A separate blood flow navigator pulse sequence is interleaved with the fMRI data acquisition to monitor blood flow in arteries that feed the brain tissue. Information in the blood flow navigator data is used to reduce errors in the fMRI data due to tissue motion caused by pulsatile blood flow. In one embodiment the blood flow navigator information is used to gate the fMRI acquisition and in another embodiment the information is used to retrospectively correct acquired fMRI data. |
FILED | Monday, April 16, 2007 |
APPL NO | 11/735578 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/306 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433727 | Ward et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Legacy Good Samaritan Hospital and Medical Center (Portland, Oregon) |
INVENTOR(S) | W. Kenneth Ward (Portland, Oregon); Michael D. Wood (Portland, Oregon) |
ABSTRACT | The invention consists of a sensor with multiple indicating (sensing) electrodes covered with a selectively permeable membrane for monitoring fluid concentrations in a biological environment. The indicating electrodes respond to changes in certain analytes, such as glucose, through an enzyme-mediated reaction. The currents generated from the enzyme-mediated reactions are transmitted through radio signals to an external receiver where the information is processed and recorded. Through the use of various biomaterials and biochemicals associated with the sensor, the monitoring accuracy is improved and the overall viability is prolonged. The process of foreign body fibrosis (formation of a scar capsule around the implanted sensor) eventually limits the functional life of the device. We teach methods of delivery of certain biochemicals that can increase the functional life of the sensor by inhibiting the formation of the foreign body capsule or by stimulating the growth of capillaries into the capsule. |
FILED | Friday, September 24, 2004 |
APPL NO | 10/948954 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/345 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07430928 | Grate et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Insititute (Richland, Washington) |
INVENTOR(S) | Jay W. Grate (West Richland, Washington); David L. Baldwin (Kennewick, Washington); Norman C. Anheier, Jr. (Richland, Washington) |
ABSTRACT | An apparatus and method are disclosed for pre-concentrating gaseous vapors for analysis. The invention finds application in conjunction with, e.g., analytical instruments where low detection limits for gaseous vapors are desirable. Vapors sorbed and concentrated within the bed of the apparatus can be thermally desorbed achieving at least partial separation of vapor mixtures. The apparatus is suitable, e.g., for preconcentration and sample injection, and provides greater resolution of peaks for vapors within vapor mixtures, yielding detection levels that are 10-10,000 times better than for direct sampling and analysis systems. Features are particularly useful for continuous unattended monitoring applications. |
FILED | Wednesday, February 08, 2006 |
APPL NO | 11/350716 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/863.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431011 | Wagner et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Robert M. Wagner (Knoxville, Tennessee); Charles S. Daw (Knoxville, Tennessee); Johney B. Green (Knoxville, Tennessee); Kevin D. Edwards (Knoxville, Tennessee) |
ABSTRACT | This invention is a method of achieving stable, optimal mixtures of HCCI and SI in practical gasoline internal combustion engines comprising the steps of: characterizing the combustion process based on combustion process measurements, determining the ratio of conventional and HCCI combustion, determining the trajectory (sequence) of states for consecutive combustion processes, and determining subsequent combustion process modifications using said information to steer the engine combustion toward desired behavior. |
FILED | Friday, February 02, 2007 |
APPL NO | 11/670485 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion engines 123/299 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431084 | Upadhye |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ravindra S. Upadhye (Pleasanton, California) |
ABSTRACT | A system of obtaining hydrogen from a coal seam by providing a production well that extends into the coal seam; positioning a conduit in the production well leaving an annulus between the conduit and the coal gasification production well, the conduit having a wall; closing the annulus at the lower end to seal it from the coal gasification cavity and the syngas; providing at least a portion of the wall with a bifunctional membrane that serves the dual purpose of providing a catalyzing reaction and selectively allowing hydrogen to pass through the wall and into the annulus; and producing the hydrogen through the annulus. |
FILED | Monday, September 11, 2006 |
APPL NO | 11/519688 |
ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Wells 166/265 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431348 | Casper et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | William L. Casper (Rigby, Idaho); Don T. Clark (Idaho Falls, Idaho); Blair K. Grover (Idaho Falls, Idaho); Rodney O. Mathewson (Idaho Falls, Idaho); Craig A. Seymour (Idaho Falls, Idaho) |
ABSTRACT | A drill string comprises a first drill string member having a male end; and a second drill string member having a female end configured to be joined to the male end of the first drill string member, the male end having a threaded portion including generally square threads, the male end having a non-threaded extension portion coaxial with the threaded portion, and the male end further having a bearing surface, the female end having a female threaded portion having corresponding female threads, the female end having a non-threaded extension portion coaxial with the female threaded portion, and the female end having a bearing surface. Installation methods, including methods of installing instrumented probes are also provided. |
FILED | Tuesday, January 09, 2007 |
APPL NO | 11/621448 |
ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Pipe joints or couplings 285/334 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431567 | Bevington et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northern Power Systems Inc. (Waitsfield, Vermont) |
INVENTOR(S) | Christopher M. Bevington (Waitsfield, Vermont); Garrett L. Bywaters (Waitsfield, Vermont); Clint C. Coleman (Warren, Vermont); Daniel P. Costin (Chelsea, Vermont); William L. Danforth (Rochester, Vermont); Jonathan A. Lynch (St. Johnsbury, Vermont); Robert H. Rolland (Waitsfield, Vermont) |
ABSTRACT | A wind turbine (100) comprising an electrical generator (108) that includes a rotor assembly (112). A wind rotor (104) that includes a wind rotor hub (124) is directly coupled to the rotor assembly via a simplified connection. The wind rotor and generator rotor assembly are rotatably mounted on a central spindle (160) via a bearing assembly (180). The wind rotor hub includes an opening (244) having a diameter larger than the outside diameter of the central spindle adjacent the bearing assembly so as to allow access to the bearing assembly from a cavity (380) inside the wind rotor hub. The spindle is attached to a turret (140) supported by a tower (136). Each of the spindle, turret and tower has an interior cavity (172, 176, 368) that permits personnel to traverse therethrough to the cavity of the wind rotor hub. The wind turbine further includes a frictional braking system (276) for slowing, stopping or keeping stopped the rotation of the wind rotor and rotor assembly. |
FILED | Tuesday, June 01, 2004 |
APPL NO | 10/858551 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Fluid reaction surfaces 416/244.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431746 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
INVENTOR(S) | Zhiwen Ma (Sandy Hook, Connecticut); Ramakrishnan Venkataraman (New Milford, Connecticut); Lawrence J. Novacco (Brookfield, Connecticut) |
ABSTRACT | A fuel reformer having an enclosure with first and second opposing surfaces, a sidewall connecting the first and second opposing surfaces and an inlet port and an outlet port in the sidewall. A plate assembly supporting a catalyst and baffles are also disposed in the enclosure. A main baffle extends into the enclosure from a point of the sidewall between the inlet and outlet ports. The main baffle cooperates with the enclosure and the plate assembly to establish a path for the flow of fuel gas through the reformer from the inlet port to the outlet port. At least a first directing baffle extends in the enclosure from one of the sidewall and the main baffle and cooperates with the plate assembly and the enclosure to alter the gas flow path. Desired graded catalyst loading pattern has been defined for optimized thermal management for the internal reforming high temperature fuel cells so as to achieve high cell performance. |
FILED | Thursday, December 09, 2004 |
APPL NO | 11/030747 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Gas: Heating and illuminating 048/127.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431888 | Frechet et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jean M. J. Frechet (Oakland, California); Frantisek Svec (Alameda, California); Thomas Rohr (Leiden, Netherlands) |
ABSTRACT | A microfluidic device preferably made of a thermoplastic polymer that includes a channel or a multiplicity of channels whose surfaces are modified by photografting. The device further includes a porous polymer monolith prepared via UV initiated polymerization within the channel, and functionalization of the pore surface of the monolith using photografting. Processes for making such surface modifications of thermoplastic polymers and porous polymer monoliths are set forth. |
FILED | Friday, September 19, 2003 |
APPL NO | 10/665900 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431915 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (La Jolla, California) |
INVENTOR(S) | Tao Jiang (San Diego, California); Roger Y. Tsien (La Jolla, California) |
ABSTRACT | A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. Cleavage of X allows separation of A from B, unmasking the normal ability of the basic amino acids in B to drag cargo C into cells near the cleavage event. X is cleaved extracellularly, preferably under physiological conditions. D-amino acids are preferred for the A and B portions, to minimize immunogenicity and nonspecific cleavage by background peptidases or proteases. |
FILED | Friday, October 31, 2003 |
APPL NO | 10/699562 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431965 | Grigorian et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honda Motor Co., Ltd. (Tokyo, Japan) |
INVENTOR(S) | Leonid Grigorian (Raymond, Ohio); Louis Hornyak (Evergreen, Colorado); Anne C Dillon (Boulder, Colorado); Michael J Heben (Denver, Colorado) |
ABSTRACT | The invention relates to a chemical vapor deposition process for the continuous growth of a carbon single-wall nanotube where a carbon-containing gas composition is contacted with a porous membrane and decomposed in the presence of a catalyst to grow single-wall carbon nanotube material. A pressure differential exists across the porous membrane such that the pressure on one side of the membrane is less than that on the other side of the membrane. The single-wall carbon nanotube growth may occur predominately on the low-pressure side of the membrane or, in a different embodiment of the invention, may occur predominately in between the catalyst and the membrane. The invention also relates to an apparatus used with the carbon vapor deposition process. |
FILED | Monday, November 03, 2003 |
APPL NO | 10/700386 |
ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Coating processes 427/249.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432055 | Pemov et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicago Argonne LLC (Chicago, Illinois) |
INVENTOR(S) | Alexander Pemov (Charlottesville, Virginia); Sergei Bavykin (Darien, Illinois) |
ABSTRACT | Highly specific and sensitive methods were developed for multiplex amplification of nucleic acids on supports such as microarrays. Based on a specific primer design, methods include five types of amplification that proceed in a reaction chamber simultaneously. These relate to four types of multiplex amplification of a target DNA on a solid support, directed by forward and reverse complex primers immobilized to the support and a fifth type—pseudo-monoplex polymerase chain reaction (PCR) of multiple targets in solution, directed by a single pair of unbound universal primers. The addition of the universal primers in the reaction mixture increases the yield over the traditional “bridge” amplification on a solid support by approximately ten times. Methods that provide multitarget amplification and detection of as little as 0.45-4.5×10−12 g (equivalent to 102-103 genomes) of a bacterial genomic DNA are disclosed. |
FILED | Friday, March 05, 2004 |
APPL NO | 10/794381 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432092 | Schultz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California) |
ABSTRACT | Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with keto amino acids using these orthogonal pairs. |
FILED | Wednesday, October 15, 2003 |
APPL NO | 10/530421 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432229 | Paranthaman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Mariappan P. Paranthaman (Knoxville, Tennessee); Tolga Aytug (Knoxville, Tennessee) |
ABSTRACT | Laminated, biaxially textured superconductors include Ir-based buffer layers and/or substrates. |
FILED | Tuesday, March 23, 2004 |
APPL NO | 10/809174 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Superconductor technology: Apparatus, material, process 55/238 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432419 | Gupta |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Goutam Gupta (Santa Fe, New Mexico) |
ABSTRACT | Chimeric anti-microbial proteins, compositions, and methods for the therapeutic and prophylactic treatment of plant diseases caused by the bacterial pathogen Xylella fastidiosa are provided. The anti-microbial proteins of the invention generally comprise a surface recognition domain polypeptide, capable of binding to a bacterial membrane component, fused to a bacterial lysis domain polypeptide, capable of affecting lysis or rupture of the bacterial membrane, typically via a fused polypeptide linker. In particular, methods and compositions for the treatment or prevention of Pierce's disease of grapevines are provided. Methods for the generation of transgenic Vitus vinefera plants expressing xylem-secreted anti-microbial chimeras are also provided. |
FILED | Friday, May 14, 2004 |
APPL NO | 10/846172 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/302 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432516 | Peggs et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | Stephen G. Peggs (Port Jefferson, New York); J. Michael Brennan (East Northport, New York); Joseph E. Tuozzolo (Sayville, New York); Alexander Zaltsman (Commack, New York) |
ABSTRACT | A medical synchrotron which cycles rapidly in order to accelerate particles for delivery in a beam therapy system. The synchrotron generally includes a radiofrequency (RF) cavity for accelerating the particles as a beam and a plurality of combined function magnets arranged in a ring. Each of the combined function magnets performs two functions. The first function of the combined function magnet is to bend the particle beam along an orbital path around the ring. The second function of the combined function magnet is to focus or defocus the particle beam as it travels around the path. The radiofrequency (RF) cavity is a ferrite loaded cavity adapted for high speed frequency swings for rapid cycling acceleration of the particles. |
FILED | Tuesday, January 24, 2006 |
APPL NO | 11/337916 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/492.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433441 | Jenkins et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Silicon Graphics, Inc. (Sunnyvale, California) |
INVENTOR(S) | Philip Nord Jenkins (Eau Claire, Wisconsin); Frank N. Cornett (Chippewa Falls, Wisconsin) |
ABSTRACT | A system and method of reducing skew between a plurality of signals transmitted with a transmit clock is described. Skew is detected between the received transmit clock and each of received data signals. Delay is added to the clock or to one or more of the plurality of data signals to compensate for the detected skew. The delay added to each of the plurality of delayed signals is updated to adapt to changes in detected skew. |
FILED | Monday, April 17, 2006 |
APPL NO | 11/405387 |
ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Pulse or digital communications 375/371 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07431242 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
INVENTOR(S) | James L. Brown (Cupertino, California); Joseph A. Garcia (Belmont, California); Dinesh K. Prabhu (Fremont, California) |
ABSTRACT | A convex shell structure for enhanced aerodynamic performance and/or reduced heat transfer requirements for a space vehicle that re-enters an atmosphere. The structure has a fore-body, an aft-body, a longitudinal axis and a transverse cross sectional shape, projected on a plane containing the longitudinal axis, that includes: first and second linear segments, smoothly joined at a first end of each the first and second linear segments to an end of a third linear segment by respective first and second curvilinear segments; and a fourth linear segment, joined to a second end of each of the first and second segments by curvilinear segments, including first and second ellipses having unequal ellipse parameters. The cross sectional shape is non-symmetric about the longitudinal axis. The fourth linear segment can be replaced by a sum of one or more polynomials, trigonometric functions or other functions satisfying certain constraints. |
FILED | Tuesday, November 01, 2005 |
APPL NO | 11/265324 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/158.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431243 | Allen |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Michael J. Allen (Tehachapi, California) |
ABSTRACT | The present invention provides a practical method for UAVs to take advantage of thermals in a manner similar to piloted aircrafts and soaring birds. In general, the invention is a method for a UAV to autonomously locate a thermal and be guided to the thermal to greatly improve range and endurance of the aircraft. |
FILED | Thursday, March 23, 2006 |
APPL NO | 11/277325 |
ART UNIT | 4114 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/195 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432780 | Chan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
INVENTOR(S) | Steven S. Chan (Alhambra, California); Te Kao Wu (Rancho Palos Verde, California); Arun K. Bhattacharvyya (El Segundo, California) |
ABSTRACT | A rectangular-to-circular mode combiner/divider is provided. In one aspect of the invention, a power combiner is provided that comprises a plurality of rectangular waveguide ports arranged in an integral arrangement. Each rectangular waveguide port is operative to operate in a rectangular mode. The power combiner is also includes a circular waveguide port operative to operate in a circular mode, and a transition body that couples the plurality of rectangular waveguide ports to the circular waveguide port. The transition body has an inner transition cavity and an outer body operative to convert radio frequency (RF) signals between the rectangular mode and the circular mode, and provide a combined output signal at the circular waveguide port from RF signals received at the plurality rectangular waveguide ports. |
FILED | Wednesday, November 23, 2005 |
APPL NO | 11/287414 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Wave transmission lines and networks 333/127 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07431796 | Martin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Kevin P. Martin (Atlanta, Georgia); Harry P. Gillis (Los Angeles, California); Dmitri A. Choutov (Santa Clara, California) |
ABSTRACT | An apparatus for low-damage, anisotropic etching of substrates having the substrate mounted upon a mechanical support located within an ac or dc plasma reactor. The mechanical support is independent of the plasma reactor generating apparatus and capable of being electrically biased. The substrate is subjected to a plasma of low-energy electrons and a species reactive with the substrate. An additional structure capable of being electrically biased can be placed within the plasma to control further the extraction or retardation of particles from the plasma. |
FILED | Monday, February 23, 2004 |
APPL NO | 10/784697 |
ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/345.430 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431929 | Jacobs et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Arizona Board of Regents (Tempe, Arizona) |
INVENTOR(S) | Bertram Jacobs (Tempe, Arizona); Sangeetha Vijaysri (San Diego, California); James Jancovich (Tempe, Arizona); Latha Talasela (Phoenix, Arizona) |
ABSTRACT | The present invention relates to vaccines having an increased level of safety comprising recombinant vaccinia viruses containing an inactivated E3L region. The invention also relates to methods for stimulating a protective immune response in an immunized host using the vaccines of the invention. The invention is based on the discovery that vaccinia virus mutants having deletions in the E3L region exhibit dramatically reduced pathogenesis while remaining highly immunogenic. In addition, the invention relates to modified recombinant vaccinia viruses engineered to express heterologous polypeptides and the use of such viruses in vaccines designed to stimulate a protective immune response against such polypeptides in a host. The invention further relates to an interferon-sensitive recombinant vaccinia virus with broad host range wherein a salamander eIF2α is inserted into the viral genome in place of at least a portion of the E3L gene. |
FILED | Wednesday, December 22, 2004 |
APPL NO | 11/022477 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07431969 | Gleason et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Karen K. Gleason (Lexington, Massachusetts); Kelvin Chan (Santa Clara, California) |
ABSTRACT | In one embodiment of the invention, iCVD is used to form linear thin films using a radical initiator and an alkene. In another embodiment, iCVD is used to form crosslinked thin films by the addition of a crosslinking agent (e.g., a diacrylate or a dimethyacrylate). The incorporation of a crosslinking agent into the thin films is shown to increase systematically with its partial pressure. In one embodiment, when the crosslinker is EDGA and the monomer is HEMA it results in crosslinked P(HEMA-co-EGDA) copolymer. In another embodiment, when the crosslinker is EDGA and the monomer is VP, it results in crosslinked P(VP-co-EGDA). Disclosed are the effects of crosslinker incorporation on the thermal and the wetting properties of the polymers. The unique swelling properties of these films are also described; certain films of the present invention are hydrogels when soaked in water. |
FILED | Friday, August 05, 2005 |
APPL NO | 11/198932 |
ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Coating processes 427/255.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
US 07432868 | Webb et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Spencer Webb (Pelham, New Hampshire); David Martin (Nashua, New Hampshire) |
ABSTRACT | A low power, lightweight, collapsible and rugged antenna positioner for use in communicating with geostationary, geosynchronous and low earth orbit satellite. By collapsing, invention may be easily carried or shipped in a compact container. May be used in remote locations with simple or automated setup and orientation. Azimuth is adjusted by rotating an antenna in relation to a positioner base and elevation is adjusted by rotating an elevation motor coupled with the antenna. Manual orientation of antenna for linear polarized satellites yields lower weight and power usage. Updates ephemeris or TLE data via satellite. Algorithms used for search including Clarke Belt fallback, transponder/beacon searching switch, azimuth priority searching and tracking including uneven re-peak scheduling yield lower power usage. Orientation aid via user interface allows for smaller azimuth motor, simplifies wiring and lowers weight. Tilt compensation, bump detection and failure contingency provide robustness. |
FILED | Wednesday, April 26, 2006 |
APPL NO | 11/412720 |
ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Radio wave antennas 343/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433806 | Berk et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Spectral Sciences, Inc. (Burlington, Massachusetts) |
INVENTOR(S) | Alexander Berk (Sharon, Massachusetts); Prabhat K. Acharya (Burlington, Massachusetts); Lawrence S. Bernstein (Lexington, Massachusetts); Gail P. Anderson (Boulder, Colorado); Paul Lewis (Falls Church, Virginia); James H. Chetwynd (Stoneham, Massachusetts); Michael L. Hoke (Leominster, Massachusetts) |
ABSTRACT | A radiative transport band model algorithm has been developed for prediction and analysis of high spectral resolution radiometric measurements. Atomic and molecular line center absorption is determined from finite spectral bin equivalent widths. A new mathematically exact expansion for finite bin equivalent widths provides high accuracy at any desired spectral resolution. The temperature and pressure dependent Voigt line tail spectral absorption contributing to each spectral bin is pre-computed and fit to Padé approximants for rapid and accurate accounting of neighboring-to-distant lines. |
FILED | Friday, April 20, 2001 |
APPL NO | 09/838801 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07431935 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Zhong Zhang (New Bedford, Massachusetts) |
ABSTRACT | The invention features a polypeptide complex synthesized by bacteria of the genus Clostridia that contains the serotype E botulinum neurotoxin and five neurotoxin associated polypeptides having molecular weights of about 118, 80, 65, 40, and 18 kDa. respectively. The complex is useful in the treatment of diseases or conditions that are caused by excessive release of acetylcholine from presynaptic nerve terminals. |
FILED | Tuesday, January 27, 2004 |
APPL NO | 10/766283 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07432118 | Cox et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Finisar Corporation (Sunnyvale, California) |
INVENTOR(S) | James A. Cox (New Brighton, Minnesota); Eva Strzelecka (Cupertino, California) |
ABSTRACT | A VCSEL with current confinement achieved by an oxide insulating region and by an ion implant region. An annular shaped oxide layer is formed, and a gain guide ion implant is formed. The ion implant gain guide includes a central region having high conductivity. The VCSEL further includes first and second mirrors that are separated by an optical path of at least one wavelength. Furthermore, the oxide insulating region beneficially has a optical path of less than ¼ wavelength. The ion implanted spatial region is beneficially concentrically aligned with the oxide insulating region. |
FILED | Monday, June 06, 2005 |
APPL NO | 11/147135 |
ART UNIT | 2813 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/32 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 07432264 | Jefferson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Isis Pharmaceuticals, Inc. (Carlsbad, California) |
INVENTOR(S) | Elizabeth Anne Jefferson (La Jolla, California); Eric E. Swayze (Carlsbad, California); Punit P. Seth (San Marcos, California); Dale E. Robinson, Jr. (San Marcos, California) |
ABSTRACT | Provided are antibacterial biaryl compounds having micromolar MIC activity against Gram-negative and Gram-positive pathogens, including a methicillin-resistant S. aureus strain. |
FILED | Monday, August 09, 2004 |
APPL NO | 10/914256 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/249 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07430929 | Vroblesky |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Interior (Washington, District of Columbia) |
INVENTOR(S) | Don A. Vroblesky (Columbia, South Carolina) |
ABSTRACT | A method and device for sampling pore water, including an elongated tubular outer body having a grid framework forming multiple perforations throughout the entire outer body. The grid framework surrounding the perforations has raised and beveled sides. An elongated, perforated tubular inner body is contained within the outer body. The inner body has a diameter less than a diameter of the outer body, which forms a cavity between the inner body and the outer body. The cavity is filled with an inert granular filler material. A first outer cap and a second outer cap cover respective ends of the outer body. A coupling is placed in fluid communication with the inner body and protrudes through the first outer cap. A tube is attached to the coupling protruding through the first outer cap to transfer a water sample to a sample collection site. |
FILED | Thursday, April 06, 2006 |
APPL NO | 11/401011 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/863.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432090 | Bennett et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Rice University (Houston, Texas) |
INVENTOR(S) | George N. Bennett (Houston, Texas); Miles C. Scotcher (Seattle, Washington) |
ABSTRACT | We have shown that the control of solventogenesis and sporulation can be genetically uncoupled in C. acetobutylicum. In strain 824(pASspo), the absence of SpoIIE causes sporulation to be blocked at stage II. The cell remains in a vegetative state, and this allows solvent production to proceed for longer and for solvents to accumulate more rapidly and to a higher concentration. The characteristic drop in OD600 observed in wild type and control strains of C. acetobutylicum after 48-72 hours as the cells transition from the solventogenic phase to sporulation is notably absent in the fermentations of 824(pASspo). Mutant S (wild type background, spoIIE disrupted), Mutant BS (Mutant B background, spoIIE disrupted), Mutant HS (Mutant H background, spoIIE disrupted) and Mutant bukS (buk- background, spoIIE disrupted) were generated to create stable solvent producing bacteria with complete inactivation of the SpoIIE protein. Similarity between the SpoIIE protein of C. acetobutylicum, B. subtilis, and other Clostridial species indicates that the techniques used in C. acetobutylicum can be applied to other solvent producing Clostridia. |
FILED | Friday, July 01, 2005 |
APPL NO | 11/173542 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/132 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07432872 | Waller |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary (Washington, District of Columbia) |
INVENTOR(S) | Marsellas L. Waller (Huntsville, Alabama) |
ABSTRACT | A reduced height log periodic antenna that may safely be positioned under the rotating blades of a helicopter sitting on the ground and still resonate in the frequency range at which the antenna was originally designed to resonate. The antenna comprises a pair of antenna booms, a first plurality of vertical antenna radiating elements connected to the booms, and a second plurality of vertical antenna radiating elements connected to the booms. In addition, the antenna includes a plurality of tuned horizontal antenna radiating elements, each tuned horizontal radiating element being connected to the top of one of the second plurality of vertical antenna radiating elements, and a plurality of tuned upwardly bent horizontal antenna radiating elements, each tuned upwardly bent horizontal antenna radiating element being connected to the bottom of one of the second plurality of vertical antenna radiating elements. The antenna is characterized by the fact that the second plurality of antenna radiating elements have been shortened from their original design length to fit vertically under the rotating blades of a helicopter, and the tuned horizontal radiating elements have been added to the shortened radiating elements to bring the shortened radiating elements back to their desired frequency response. |
FILED | Friday, April 27, 2007 |
APPL NO | 11/796461 |
ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Radio wave antennas 343/792.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07433811 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jun Gao (Kingston, Canada); Michael J. Sailor (La Jolla, California); Sangeeta Bhatia (La Jolla, California); Christopher Flaim (Modesto, California) |
ABSTRACT | The invention is directed to methods for direct patterning of silicon. The invention provides the ability to fabricate complex surfaces in silicon with three dimensional features of high resolution and complex detail. The invention is suitable, for example, for use in soft lithography as embodiments of the invention can quickly create a master for use in soft lithography. In an embodiment of the invention, electrochemical etching of silicon, such as a silicon wafer, for example, is conducted while at least a portion of the silicon surface is exposed to an optical pattern. The etching creates porous silicon in the substrate, and removal of the porous silicon layer leaves a three-dimensional structure correlating to the optical pattern. |
FILED | Tuesday, May 04, 2004 |
APPL NO | 10/838859 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 07, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20081007.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page