FedInvent™ Patents
Patent Details for Tuesday, November 04, 2008
This page was updated on Monday, March 27, 2023 at 01:00 AM GMT
Department of Defense (DOD)
| US 07444838 | Pickrell et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Gary Pickrell (Blacksburg, Virginia); Daniel Kominsky (Blacksburg, Virginia); Roger Stolen (Blacksburg, Virginia); Jeong I. Kim (Suwon, South Korea); Anbo Wang (Blacksburg, Virginia); Ahmad Safaai-Jazi (Blacksburg, Virginia) |
| ABSTRACT | A random array of holes is created in an optical fiber by gas generated during fiber drawing. The gas forms bubbles which are drawn into long, microscopic holes. The gas is created by a gas generating material such as silicon nitride. Silicon nitride oxidizes to produce nitrogen oxides when heated. The gas generating material can alternatively be silicon carbide or other nitrides or carbides. The random holes can provide cladding for optical confinement when located around a fiber core. The random holes can also be present in the fiber core. The fibers can be made of silica. The present random hole fibers are particularly useful as pressure sensors since they experience a large wavelength dependant increase in optical loss when pressure or force is applied. |
| FILED | Wednesday, June 09, 2004 |
| APPL NO | 10/863805 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Glass manufacturing 065/435 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07444868 | Johnson |
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| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Burgess R. Johnson (Bloomington, Minnesota) |
| ABSTRACT | MEMS devices and methods employing one or more electrodes coupled to a time-varying rebalancing voltage are disclosed. A MEMS inertial sensor in accordance with an illustrative embodiment can include one or more proof masses, at least one sense electrode positioned adjacent to each proof mass, and one or more torquer electrodes. Rebalancing voltages can be applied to the torquer electrodes to electrostatically null quadrature and/or Coriolis-related proof mass motion along a sense axis of the device. The rebalancing voltages applied to each of the torquer electrodes can be adjusted using feedback from one or more force rebalancing control loops. |
| FILED | Thursday, June 29, 2006 |
| APPL NO | 11/427767 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07444869 | Johnson et al. |
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| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Burgess R. Johnson (Bloomington, Minnesota); Eugen I. Cabuz (Eden Prairie, Minnesota) |
| ABSTRACT | MEMS devices and methods for measuring Coriolis forces using force rebalancing and parametric gain amplification techniques are disclosed. A MEMS inertial sensor can include one or more proof masses, at least one sense electrode positioned adjacent to each proof mass, a number of torquer electrodes for electrostatically nulling quadrature and Coriolis-related proof mass motion, and a number of pump electrodes for producing a pumping force on the proof masses. Force rebalancing voltages can be applied to some torquer electrodes to electrostatically null quadrature and/or Coriolis-related proof mass motion along a sense axis of the device. A pumping voltage at approximately twice the motor drive frequency of the proof masses can be used to pump the proof masses along the sense axis. |
| FILED | Monday, October 16, 2006 |
| APPL NO | 11/549769 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07444880 | Zhang et al. |
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| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Rongjing Zhang (Pasadena, California); Guruswami Ravichandran (Arcadia, California); Doron Shilo (Pasadena, California); Kaushik Bhattacharya (Pasadena, California) |
| ABSTRACT | The present invention relates to the field measuring the mechanical response of micro-electro-mechanical systems. More specifically, the present invention pertains to a method and apparatus that allows the direct control of the load applied to a Micro-Electro-Mechanical System in order to measure the mechanical response. The system comprises a loading sub-system, a displacement measurement sub-system, and an optional observation sub-system. |
| FILED | Monday, December 13, 2004 |
| APPL NO | 11/011320 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/779 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07444883 | Novack |
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| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Mitchell J. Novack (Kenmore, Washington) |
| ABSTRACT | An apparatus and method for monolithic force transducers in which a sensed force is applied across only two ends of a pair of force sensing elements so that the pair of force sensing elements are loaded in series with one in compression and the other in tension, whereby the force sensed by each of the two force sensing elements are identically equal in magnitude but opposite in sense. |
| FILED | Thursday, December 22, 2005 |
| APPL NO | 11/317384 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/826 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07444891 | Chadwick et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David Bartholomew Chadwick (San Diego, California); Ignacio Rivera-Duarte (San Diego, California); Robert Martin Cook (Escondido, California) |
| ABSTRACT | A method includes providing a sampling device having a sampling chamber therein, a pump operatively coupled to the sampling chamber, and a drive means coupled to the sampling chamber; situating the sampling device against an underwater boat hull having contaminants attached thereto, wherein situating the sampling device against the underwater boat hull causes water to be disposed within the sampling chamber; activating the pump to remove a portion of the water from the sampling chamber, wherein negative pressure is created within the sampling chamber and a watertight seal is formed between the sampling chamber and the underwater boat hull; activating the drive means to remove a sample of the contaminants from the underwater boat hull, wherein the sample of the contaminants is collected in the sampling chamber; deactivating the mechanical drive means; and sealing the sampling chamber, wherein the sample of the contaminants is stored within the sampling chamber. |
| FILED | Wednesday, June 07, 2006 |
| APPL NO | 11/449181 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/864.560 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07444919 | Mansfield |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis A. Mansfield (Colonial Beach, Virginia) |
| ABSTRACT | An electromagnetic (EM) launcher that receives electrical power is provided for ejecting a projectile. The launcher includes an armature for holding the projectile and a launch conduit for accelerating the armature along a longitudinal direction and thereby ejecting the projectile. The armature includes a Halbach array. The conduit includes a multi-phase linear synchronous motor (LSM) drive and short conducting elements. The Halbach array forms a plurality of concentric rings disposed longitudinally along the armature. Each ring contains a plurality of magnets distributed concentrically. Each magnet in the corresponding ring has a magnetic field oriented with north direction of the magnetic field pointing at one of radially inward, radially outward, longitudinally inward and longitudinally outward. |
| FILED | Tuesday, August 29, 2006 |
| APPL NO | 11/513438 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445094 | Henderson et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin K. Henderson (Albuquerque, New Mexico); Steven F. Griffin (Albuquerque, New Mexico); Joel D. Gussy (Chantilly, Virginia); Steven A. Lane (Albuquerque, New Mexico); Elizabeth L. C. Jensen (Redondo Beach, California); Richard K. Davies (Rochester Hills, Michigan); Jennifer A. Gruits (Royal Oak, Michigan); Paul W. Alexander (Ann Arbor, Michigan); David M. Stevens (Athens, Michigan); Ryan D. Majkrzak (San Clemente, California) |
| ABSTRACT | A fixture is isolated from the transmission of vibration emanating from a vibration source by a damper containing magneto-rheological (“MR”) fluid and a plunger mechanically coupling the damper and the fixture. The isolation apparatus is mechanically coupled to the vibration source. The viscosity of the MR fluid contained in the damper is controlled by a magnetic field produced by the vibration of an isolation system responsive to the vibration of the vibration source. The resonant frequency of the isolation system is adjusted to approximate that of the fixture. |
| FILED | Tuesday, October 11, 2005 |
| APPL NO | 11/251008 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Brakes 188/267 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445132 | Williams |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael W. Williams (Portsmouth, Rhode Island) |
| ABSTRACT | A gas cartridge actuation state determination system includes a puncture pin adapted to abut an end of the gas cartridge. A load sensor coupled to and in line with the puncture pin. A spring bears against the load sensor. The spring's force is such that it is insufficient to cause the puncture pin to be driven through the end of the gas cartridge when the end has not been punctured, but is sufficient to cause the puncture pin to be driven through the end of the gas cartridge when the end has already been punctured. In addition, the spring's force is such that it will be approximately zero after the puncture pin has been driven through the end that has already been punctured. A device coupled to the load sensor determines when the spring force is approximately zero. |
| FILED | Wednesday, August 24, 2005 |
| APPL NO | 11/217857 |
| ART UNIT | 3754 — Fluid Handling and Dispensing |
| CURRENT CPC | Dispensing 222/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445299 | Gonzalez |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | René G. Gonzalez (Southfield, Michigan) |
| ABSTRACT | A band track for a tracked vehicle having enhanced resistance to mines includes a plurality of track pad units disposed on the bearing surface of the track band. The track pad units have extended end walls of sufficient height to distance the vulnerable portion of the band track from the shearing force of an exploding mine. These end walls are sufficiently strong to support the vehicle as it traverses terrain, but are configured to collapse in controlled manner under the force of an exploding mine. Such explosion forces a specifically configured front end wall of a trailing track pad to engage the matingly configured end wall of the leading track pad. The resulting mating juxtaposition of the adjacent end walls forms a relatively continuous physical barrier protecting the vulnerable section of the band track from shrapnel and other entrained ejecta of the explosion. |
| FILED | Thursday, July 06, 2006 |
| APPL NO | 11/482304 |
| ART UNIT | 3617 — Fluid Handling and Dispensing |
| CURRENT CPC | Wheel substitutes for land vehicles 35/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445671 | Sunkara et al. |
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| ASSIGNEE(S) | University of Louisville (Louisville, Kentucky); University of Kentucky (Lexington, Kentucky) |
| INVENTOR(S) | Mahendra Kumar Sunkara (Louisville, Kentucky); Shashank Sharma (Mountain View, California); Burtron H. Davis (Georgetown, Kentucky); Uschi M. Graham (Lexington, Kentucky) |
| ABSTRACT | A method of producing networks of low melting metal oxides such as crystalline gallium oxide comprised of one-dimensional nanostructures. Because of the unique arrangement of wires, these crystalline networks defined as “nanowebs”, “nanowire networks”, and/or “two-dimensional nanowires”. Nanowebs contain wire densities on the order of 109/cm2. A possible mechanism for the fast self-assembly of crystalline metal oxide nanowires involves multiple nucleation and coalescence via oxidation-reduction reactions at the molecular level. The preferential growth of nanowires parallel to the substrate enables them to coalesce into regular polygonal networks. The individual segments of the polygonal network consist of both nanowires and nanotubules of β-gallium oxide. The synthesis of highly crystalline noncatalytic low melting metals such as β-gallium oxide tubes, nanowires, and nanopaintbrushes is accomplished using molten gallium and microwave plasma containing a mixture of monoatomic oxygen and hydrogen. Gallium oxide nanowires were 20-100 nm thick and tens to hundreds of microns long. Transmission electron microscopy (TEM) revealed the nanowires to be highly crystalline and devoid of any structural defects. Results showed that multiple nucleation and growth of gallium oxide nanostructures can occur directly out of molten gallium exposed to appropriate composition of hydrogen and oxygen in the gas phase. The method of producing nanowebs is extendible to other low melting metals and their oxides such as for example: zinc oxide, tin oxide, aluminum oxide, bismuth oxide, and titanium dioxide. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/869489 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445717 | Cha et al. |
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| ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel K. Cha (Newark, Delaware); Seok-Young Oh (Newark, Delaware); Pei C. Chiu (Hockessin, Delaware); Byung J. Kim (Champaign, Illinois) |
| ABSTRACT | A waste stream is treated in a pre-filter having media, preferably sand, connected below a zero-valent metal column reactor incorporating a metal with reducing potential, preferably elemental iron (Fe0); the combination preferably configured as a single unit. The waste stream is pumped through the pre-filter to trap solids and deoxygenate it, then enters the reactor and is subjected to a reducing process. Most of the Fe0 is transformed to the ferrous ion (Fe+2), mixed with the reduced product, and fed to a continuous stirred tank reactor (CSTR) in which Fenton oxidation occurs. The output is then sent to a sedimentation tank and pH-neutralized using a strong base such as sodium hydroxide (NaOH). The aqueous portion is drawn off and the sludge pumped from the sedimentation tank. The system is monitored and controlled to optimize required additives, while monitoring of pressure drop across the pre-filter and column reactor establishes replacement requirements. |
| FILED | Thursday, September 08, 2005 |
| APPL NO | 11/229441 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid purification or separation 210/709 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445753 | Kreis et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Richard J. Kreis (Bel Air, Maryland); Robert J. Pazda (Kingsville, Maryland) |
| ABSTRACT | An automated ampoule breaking device includes a carriage having an opening for receiving and securely retaining a substrate in a substantially upright position, wherein the substrate includes at least one flexible compartment each having an outlet at the lower end and at least one ampoule contained therein; and at least one movable projection operatively associated with the carriage, wherein each of the at least one projection adapted for applying sufficient pressure progressing from the upper to the lower end of the corresponding flexible compartment to crush the at least one ampoule and direct the contents of the crushed ampoule out of the respective flexible compartment through the outlet. |
| FILED | Tuesday, March 28, 2006 |
| APPL NO | 11/398729 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445799 | Sarangapani et al. |
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| ASSIGNEE(S) | ICET, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Shantha Sarangapani (Walpole, Massachusetts); Quoc T. Truong (Hyde Park, Massachusetts) |
| ABSTRACT | An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same. |
| FILED | Thursday, June 21, 2001 |
| APPL NO | 09/886663 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/618 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445845 | Therien et al. |
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| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael J. Therien (Philadelphia, Pennsylvania); Harry Tetsuo Uyeda (College Park, Maryland) |
| ABSTRACT | Novel multichromophoric complexes comprising the formula R1—RA-[MC]-([RM]z-[MC])m-RA—R2 are provided. Polymeric compositions and devices comprising the same are also discussed. The complexes are characterized by a central bridging moiety comprising one or a plurality of linked conjugated macrocyclic molecules [MC] coupled to at least one inorganic moiety (R1 and/or R2) through organic linker RA. Preparation methods include metal-mediated cross-coupling techniques. The complexes can be useful in nonlinear optical devices and other optoelectronic applications. |
| FILED | Friday, March 28, 2003 |
| APPL NO | 10/403387 |
| ART UNIT | 1796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Stock material or miscellaneous articles 428/411.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445908 | Paul |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Buddha D. Paul (Germantown, Maryland) |
| ABSTRACT | A method of detecting oxidants in a biological sample comprising: adding a source of ferrous ions to said sample, whereby the presence of oxidants in said sample oxidize at least a portion of said ferrous ions to ferric ions; adding a chromogenic compound to said sample, whereby said chromogenic compound reacts with at least a portion of any ferric ions present in said sample; and detecting for the product of said chromogenic compound-ferric ion reaction; whereby the detection of said chromogenic compound-ferric ion reaction product indicates the presence of oxidants in said sample. The method of detecting adulteration of a urine sample also comprises adding a source of ferrous ions to a urine sample; adding a chromogenic compound to said urine sample; detecting the presence or absence of a chromogenic reaction product; determining a concentration of said chromogenic reaction product; and determining if said concentration signifies adulteration of said urine sample. |
| FILED | Tuesday, April 20, 2004 |
| APPL NO | 10/827282 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445927 | Maga et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gerardo F. Maga (Thosand Oaks, California); Frederick E. Goetz (Oxnard, California) |
| ABSTRACT | A 10,000 gallon sequencing batch reactor tank for the on-site bio-degradation of oily sludge. Bacteria already present in and adapted to oily sludge degrade the hydrocarbons found in oily sludge within two weeks from 20,000 ppm to less than 100 ppm. A degradation cycle requires 5 days. After five days a recirculation pump and aeration system are turned off and solids are allowed to settle to the bottom of the tank. An ultrafiltration unit connected to the tank requires approximately 16 hours to process the contents of the reactor tank. |
| FILED | Friday, September 03, 2004 |
| APPL NO | 10/943653 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/289.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445977 | Chu et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Jack O. Chu (Manhasset Hills, New York); Michael A. Cobb (Croton on Hudson, New York); Philip A. Saunders (Millwood, New York); Leathen Shi (Yorktown Heights, New York) |
| ABSTRACT | A method for achieving a substantially defect free SGOI substrate which includes a SiGe layer that has a high Ge content of greater than about 25 atomic % using a low temperature wafer bonding technique is described. The wafer bonding process described in the present application includes an initial prebonding annealing step that is capable of forming a bonding interface comprising elements of Si, Ge and O, i.e., interfacial SiGeO layer, between a SiGe layer and a low temperature oxide layer. The present invention also provides the SGOI substrate and structure that contains the same. |
| FILED | Friday, May 04, 2007 |
| APPL NO | 11/744600 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/197 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446024 | Kamins |
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| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Theodore I Kamins (Palo Alto, California) |
| ABSTRACT | The growth of nanowires with a narrow diameter distribution is provided. The growth comprises: providing a substrate; providing a plurality of nanoparticles having a distribution of particle sizes on the substrate; initiating growth of nanowires by a vapor-liquid-solid technique; and terminating growth of the nanowires. |
| FILED | Tuesday, June 21, 2005 |
| APPL NO | 11/158760 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446182 | Georgiou et al. |
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| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Brent L. Iverson (Austin, Texas); Jennifer A. Maynard (Palo Alto, California) |
| ABSTRACT | A composition and method for treating a host having or at risk of infection by Bacillus anthracis using an affinity matured antibody or portion thereof derived from a monoclonal antibody. |
| FILED | Tuesday, November 05, 2002 |
| APPL NO | 10/288269 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446208 | Irvin et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David J. Irvin (Ridgecrest, California); Mark H. Mason (Inyokern, California) |
| ABSTRACT | A process for preparation of polymers including reacting an effective amount of tetrazole diols or tetrazole polyols with isocyanate resins to produce tetrazole based linear isocyanate polymers. |
| FILED | Friday, May 27, 2005 |
| APPL NO | 11/151179 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446298 | Stone |
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| ASSIGNEE(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Thomas W. Stone (Hellertown, Pennsylvania) |
| ABSTRACT | An optical interconnect system having a first optical sub-system and a second optical sub-system, each optical sub-system having a first end and a second end, and further having a preselected length, and a preselected width. Means are fixedly secured to the first end of the optical sub-system for emitting electromagnetic radiation and means are fixedly secured to said second end of said optical sub-system for receiving the emitted electromagnetic radiation. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385449 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446311 | Zare et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Richard N. Zare (Stanford, California); Oliver Trapp (Muelheim an der Ruhr, Germany) |
| ABSTRACT | The present invention provides a method of coating an electrospray emitter with silver and then gold utilizing wet-coating processes. First, the electrospray emitter is immersed in a silver-containing liquid solution to coat the electrospray emitter in a layer of silver. Next, the silver-coated electrospray emitter is removed from the silver solution and rinsed with water. The silver-coated electrospray emitter is then annealed to stabilize the silver layer. Once the silver layer has been stabilized, the silver-coated electrospray emitter is immersed into a gold-containing liquid solution and a voltage is applied. This voltage serves to electrochemically deposit a gold layer onto the silver layer. The gold- and silver-coated electrospray emitter is then removed from the gold-containing liquid solution and rinsed with water and, preferably, with nitric acid. |
| FILED | Thursday, January 12, 2006 |
| APPL NO | 11/332782 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446315 | Tidwell |
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| FUNDED BY |
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| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Steven C. Tidwell (Kirkland, Washington) |
| ABSTRACT | Apparatus and method for directing a laser beam at an object. Some embodiments include generating direction-control information, based on the direction-control information, directing laser energy into a first fiber at a first end of a first fiber bundle during a first time period, forming an output beam of the laser energy from the second end of the first fiber bundle, and steering the output beam of the laser energy from the first fiber in a first selected direction of a plurality of directions during the first time period, and optionally modulating an intensity of the laser energy according to a predetermined pattern. The direction-control information is based on sensing electromagnetic radiation from a scene. Some embodiments use a remote camera wire-connected to the image processor to obtain scene information, while other embodiments use a second fiber bundle to convey image information from an external remote lens to a local camera. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 11/637399 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07446324 — Methods utilizing scanning probe microscope tips and products thereof or produced thereby
| US 07446324 | Mirkin et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Richard Piner (Des Plaines, Illinois); Seunghun Hong (Seoul, South Korea) |
| ABSTRACT | The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a “pen,” a solid-state substrate (e.g., gold) as “paper,” and molecules with a chemical affinity for the solid-state substrate as “ink.” Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds. |
| FILED | Tuesday, September 28, 2004 |
| APPL NO | 10/951031 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446328 | Rigney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Loma Linda University Medical Centre (Loma Linda, California) |
| INVENTOR(S) | Nickolas S. Rigney (Redlands, California); Daniel C. Anderson (Loma Linda, California); David A. Lesyna (Redlands, California); Daniel W. Miller (Oriental, North Carolina); Michael F. Moyers (Colton, California); Chieh C. Cheng (Redlands, California); Michael A. Baumann (Riverside, California) |
| ABSTRACT | A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems. |
| FILED | Monday, April 02, 2007 |
| APPL NO | 11/695532 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446450 | Boland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Justin Scott Boland (Altadena, California); Yu-Chong Tai (Pasadena, California) |
| ABSTRACT | A system and method for generating power. The system has a first electrode member comprising a first region and a second electrode member comprising a second region. Preferably, the second electrode member is coupled to the first electrode member. An electret is coupled between the first electrode member and the second electrode member. The system has a spatial region provided between the first region of the first electrode member and the second region of the second electrode member. A volume of fluid (e.g., liquid, liquid and solids, gas and liquid, solids and gases) is provided between the first region and the second region and is adapted to move between the first region and the second region to cause a change in an electric field characteristic within a portion of the spatial region by the movement of at least a portion of the fluid within the portion of the spatial region to generate a change in voltage potential between the first electrode and the second electrode. |
| FILED | Monday, June 06, 2005 |
| APPL NO | 11/146938 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446474 | Maldonado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Applied Materials, Inc. (Santa Clara, California) |
| INVENTOR(S) | Juan Ramon Maldonado (Palo Alto, California); Francisco J. Machuca (San Francisco, California); Steven T. Coyle (Alameda, California) |
| ABSTRACT | A photocathode is capable of generating an electron beam from incident light. The photocathode comprises a light permeable support having a light receiving surface and an opposing surface. A Group III nitride layer is provided on the opposing surface of the support. The Group III nitride layer comprises at least one Group III element and nitrogen. An alkali halide layer is provided on the Group III nitride layer. The alkali halide can be a cesium halide, such as cesium bromide or iodide. |
| FILED | Friday, March 25, 2005 |
| APPL NO | 11/090094 |
| ART UNIT | 2889 — Electrical Circuits and Systems |
| CURRENT CPC | Electric lamp and discharge devices 313/542 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446584 | Elliott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Ken Elliott (Thousand Oaks, California); Susan Morton (Newbury Park, California); Mark Rodwell (Goleta, California) |
| ABSTRACT | Disclosed is a time delay generator 200 apparatus and method. The apparatus includes a time delay gate 212, a mixer 216 (a Gilbert cell circuit), and a current digital to analog converter 206. The mixer 216, comprised of first and second transistor differential pairs 218 and 220, receives an analog input signal 202 without a delay as well as a delayed input signal 210 produced by the time gate delay. The digital to analog converter regulates the relative current flow between a first control signal 232 and a second control signal 238, effectively altering the mixing of the undelayed input signal 208 and the delayed input signal 210 to generate a delayed output signal 214 with a time or phase delay substantially equal to the temporal delay represented by the digital signal input 204. The time delay generator exhibits reduced phase noise and a linear time delay response. |
| FILED | Wednesday, September 25, 2002 |
| APPL NO | 10/256099 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446608 | Abdelli |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell Inernational Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Said E. Abdelli (Minneapolis, Minnesota) |
| ABSTRACT | Variable gain amplifier (VGA) circuits and methods implemented in such circuits are disclosed. An example VGA circuit includes a differential transistor pair for receiving a differential input signal. The differential transistor pair, in operation, conducts a substantially constant current over a linear operating range of the variable gain amplifier circuit. The VGA circuit also includes a current source that is coupled with the differential transistor pair. The current source, in operation, provides the substantially constant current to the differential transistor pair. The VGA circuit further includes a variable resistance circuit coupled with the differential transistor pair. In operation, a resistance of the variable resistance circuit is adjusted such that a gain of the variable gain amplifier circuit is adjusted. Further, in operation, the VGA circuit produces a differential output signal, the differential output signal being an amplified version of the differential input signal. |
| FILED | Thursday, February 16, 2006 |
| APPL NO | 11/355673 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Amplifiers 330/254 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447055 | Kuekes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Philip J. Kuekes (Menlo Park, California); R. Stanley Williams (Portola Valley, California) |
| ABSTRACT | Various embodiments of the present invention are directed to electronic means for reading the content of a nanowire-crossbar memory. In one embodiment of the present invention, a microscale or sub-microscale signal line is interconnected with one set of parallel nanowires emanating from a nanowire-crossbar memory by configurable, nanowire-junction switches. The microscale or sub-microscale signal line serves as a single-wire multiplexer, allowing the contents of any particular single-bit storage element within the nanowire-crossbar memory to be read in a three-cycle READ operation. |
| FILED | Friday, April 22, 2005 |
| APPL NO | 11/112085 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/148 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447061 | Hynes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Owen J. Hynes (Otsego, Minnesota) |
| ABSTRACT | An MOS write transistor is connected to write coils of a magnetoresistive memory cell. The MOS write transistor controls passage of a write current into the write coils of the magnetoresistive memory cell. An array of MOS write transistors and an associated array of magnetoresistive memory cells are within a magnetoresistive memory array circuit. |
| FILED | Friday, March 02, 2007 |
| APPL NO | 11/714300 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447117 | Yang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Tsih C. Yang (Falls Church, Virginia) |
| ABSTRACT | An underwater communications system includes an antenna array, a sound transmission source for transmitting communication packets, and a receiver including a processor. The processor is programmed for receiving and detecting a Doppler-sensitive probe signal and training sequence, for estimating a channel impulse response function for correlating the received signal to yield a plurality of processed channel outputs, and for summing the channel outputs to yield a common receiver output. The common receiver output is applied to a Decision Feedback Equalizer (DFE) for adaptive correction of the inter-symbol interference and to retrieve the transmitted communication message. |
| FILED | Friday, June 24, 2005 |
| APPL NO | 11/165292 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447335 | Quintana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Alvin L. Quintana (Ridgecrest, California); Daniel Garcia (Inyokern, California) |
| ABSTRACT | The present invention relates to an apparatus for locating objects (such as exploded or unexploded ordnance). The embodiments take advantage of spectroscopic features of an object's paint or surface finish to discriminate between the object and the background area. The apparatus utilizes an optical sensor, filters and the application of pixel to pixel ratios to detect the paint on an object from a distance so that objects such as unexploded ordnance may be safely destroyed or neutralized. |
| FILED | Thursday, October 18, 2007 |
| APPL NO | 11/874520 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447534 | Kingsley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SRICO, Inc. (Columbus, Ohio) |
| INVENTOR(S) | Stuart A. Kingsley (Bexley, Ohio); Sriram S. Sriram (Powell, Ohio); Anthony A. Boiarski (Columbus, Ohio); Norman Gantz (Columbus, Ohio) |
| ABSTRACT | An electro-optic modulator modulates light in response to a life-form bio-potential to provide a bio-potential modulated light output. Modulation can be carried out as a result of capacitive coupling with the bio-potential. Phase, polarization, and intensity light modulation can be used. The light output can then be converted to electronic form for further processing. An optical power splitter is used to split light into multiple portions that are converted to electrical form. A pilot tone is used to achieve high sensitivity and synchronize multiple electro-optic modulators while phase modulation can be used to reduce noise in the bio-potential signal. Low-coherent light may be used as the light source. A housing is provided that can be hermetically-sealed and provided with electro-magnetic shielding. |
| FILED | Monday, March 21, 2005 |
| APPL NO | 11/085709 |
| ART UNIT | 3739 — Selective Visual Display Systems |
| CURRENT CPC | Surgery 6/372 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07448084 | Apap et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Frank Apap (Valley Stream, New York); Andrew Honig (East Windsor, New Jersey); Hershkop Shlomo (Brooklyn, New York); Eleazar Eskin (Santa Monica, California); Salvatore J. Stolfo (Ridgewood, New Jersey) |
| ABSTRACT | A method for detecting intrusions in the operation of a computer system is disclosed which comprises gathering features from records of normal processes that access the files system of the computer, such as the Windows registry, and generating a probabilistic model of normal computer system usage based on occurrences of said features. The features of a record of a process that accesses the Windows registry are analyzed to determine whether said access to the Windows registry is an anomaly. A system is disclosed, comprising a registry auditing module configured to gather records regarding processes that access the Windows registry; a model generator configured to generate a probabilistic model of normal computer system usage based on records of a plurality of processes that access the Windows registry and that are indicative of normal computer system usage; and a model comparator configured to determine whether the access of the Windows registry is an anomaly. |
| FILED | Monday, January 27, 2003 |
| APPL NO | 10/352343 |
| ART UNIT | 2131 — AI & Simulation/Modeling |
| CURRENT CPC | Information security 726/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
07444875 — Real time visualization of shear wave propagation in soft materials with sonoelastography
| US 07444875 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Zhe Wu (New Berlin, Wisconsin); Kevin J. Parker (Rochester, New York) |
| ABSTRACT | An ultrasound system visualizes shear wave propagation in real time by slowing down the propagation of the shear wave as seen by the ultrasound probe. The shear wave source propagates shear waves into the medium at a frequency ω. The ultrasound probe is vibrated by a vibrator at the frequency ω−Δω, where Δω is much smaller than ω. The wave propagation as seen by the ultrasound probe is slowed down by a factor Δω/ω. An appropriate value of Δω allows real-time visualization of the wave propagation. Variations include electronically producing a virtual vibration and the use of multiple shear wave sources. |
| FILED | Friday, February 17, 2006 |
| APPL NO | 11/356472 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/602 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445798 | Lemischka |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Ihor R. Lemischka (Princeton, New Jersey) |
| ABSTRACT | Isolated mammalian nucleic acid molecules encoding receptor protein tyrosine kinases expressed in primitive hematopoietic cells and not expressed in mature hematopoietic cells are provided. Also included are the receptors encoded by such nucleic acid molecules; the nucleic acid molecules encoding receptor protein tyrosine kinases having the sequences shown in FIG. 1a (murine flk-2), FIG. 1b (human flk-2) and FIG. 2 (murine flk-1); the receptor protein tyrosine kinases having the amino acid sequences shown in FIG. 1a, FIG. 1b and FIG. 2; ligands for the receptors; nucleic acid sequences that encode the ligands; and methods of stimulating the proliferation and/or differentiation of primitive mammalian hematopoietic stem cells comprising contacting the stem cells with a ligand that binds to a receptor protein tyrosine kinase expressed in primitive mammalian hematopoietic cells and not expressed in mature hematopoietic cells. |
| FILED | Monday, August 11, 2003 |
| APPL NO | 10/639603 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/577 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445888 | Rasenick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Mark M. Rasenick (Glenview, Illinois); Robert J. Donati (Chicago, Illinois); Sadamu Toki (Hokkaido, Japan) |
| ABSTRACT | The present invention relates generally to methods for assaying for agents that modify the association of Gsα with components of the plasma membrane or cytoskeleton of cells. The present invention also relates generally to methods of assaying for agents having antidepressant activity via analysis of the association of Gsα with components of the plasma membrane or cytoskeleton of cells using a fluorescent analog of Gsα and fluorescence resonance energy transfer (FRET). |
| FILED | Friday, September 29, 2006 |
| APPL NO | 11/529944 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445891 | Taylor |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | John-Stephen Taylor (St. Louis, Missouri) |
| ABSTRACT | The present invention provides methods and combinations of compositions for the modulation of diseases caused by a subject possessing a disease-specific nucleic acid sequence. Included are methods for the treatment, prevention and/or inhibition of the diseases by administering a combination of a prodrug component, drug and catalytic component such that the drug is catalytically released when contacting the combination to the disease-specific nucleic acid sequence. |
| FILED | Tuesday, July 23, 2002 |
| APPL NO | 10/201680 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445894 | Agnew et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Molecular Probes, Inc. (Eugene, Oregon) |
| INVENTOR(S) | Brian Agnew (Eugene, Oregon); Kyle R. Gee (Spring field, Oregon); Vladimir V. Martin (Eugene, Oregon) |
| ABSTRACT | The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target molecules that interact with phosphorylated target molecules or molecules capable of being phosphorylated. A binding solution is provide that comprises a phosphate-binding compound, an acid and a metal ion wherein the metal ion simultaneously interacts with an exposed phosphate group on a target molecule and the metal chelating moiety of the phosphate-binding compound forming a bridge between the phosphate-binding compound and a phosphorylated target molecule resulting in a ternary complex. The binding solution of the present invention finds use in binding and detecting immobilized and solubilized phosphorylated target molecules, isolation of phosphorylated target molecules from a complex mixture and aiding in proteomic analysis wherein kinase and phosphatase substrates and enzymes can be identified. |
| FILED | Friday, April 09, 2004 |
| APPL NO | 10/821522 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445896 | Rieder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Mark J. Rieder (Seattle, Washington); Allan Rettie (Langley, Washington) |
| ABSTRACT | The present invention relates to methods and compositions for predicting drug responses. In particular, the present invention provides methods and compositions for determining individualized Warfarin dosages based on genotype of DNA polymorphisms and haplotypes derived from them in the VKORC1 gene. |
| FILED | Monday, October 18, 2004 |
| APPL NO | 10/967879 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445897 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Rodney J. Y. Ho (Seattle, Washington); Ziping Yang (Shoreline, Washington); Danny D. Shen (Edmonds, Washington); Daniel Wu (Bellevue, Washington) |
| ABSTRACT | Provided are compositions relating to novel MDR1 polymorphisms, including nucleic acids, polypeptides, and recombinant cells, as well as methods for detection of MDR1 polymorphisms in biological samples and elucidation of the influence of MDR1 polymorphisms on MDR1 protein function. Also provided are a rat MRP1 cDNA and protein, stable cell lines expressing the rat MRP1 protein, and methods of assessing drug penetration or disposition in a cell line expressing a recombinant mammalian MRP1 or MDR1 protein, or a homolog thereof. |
| FILED | Wednesday, January 26, 2005 |
| APPL NO | 11/045578 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445910 | Dertinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Litron Laboratories, Ltd. (Rochester, New York) |
| INVENTOR(S) | Stephen D. Dertinger (Webster, New York); Siân E. Cairns (Clifton Park, New York); Svetlana L. Avlasevich (Webster, New York); Dorothea K. Torous (Rochester, New York) |
| ABSTRACT | The present invention relates a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells. The method utilizes differential staining of chromatin from dead and dying cells, to distinguish the chromatin from micronuclei and nuclei that can be detected based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of micronuclei events relative to the number of nuclei can be used to assess the DNA-damaging potential of a chemical agent, the DNA-damaging potential of a physical agent, the effects of an agent which can modify endogenously-induced DNA damage, and the effects of an agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed. |
| FILED | Friday, June 24, 2005 |
| APPL NO | 11/166433 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/40.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445926 | Mathies et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard A. Mathies (Moraga, California); William H. Grover (Berkeley, California); Alison Skelley (Berkeley, California); Eric Lagally (Oakland, California); Chung N. Liu (Albany, California) |
| ABSTRACT | Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques. |
| FILED | Monday, December 29, 2003 |
| APPL NO | 10/750533 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445931 | Condie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Bresagen, Inc. (Athens, Georgia); Medical College of Georgia Research Institute (Augusta, Georgia) |
| INVENTOR(S) | Brian G. Condie (Athens, Georgia); Erhard Bieberich (Augusta, Georgia) |
| ABSTRACT | The present invention provides compositions and methods for human neural cell production. More particularly, the present invention provides cellular differentiation methods employing amphiphilic lipid compounds, preferably ceramide analogs of the β-hydroxyalkylamine type and optionally employing an essentially serum free MEDII conditioned medium for the generation of human neural cells from pluripotent human cells. The methods alternatively comprise modulating apoptosis by modifying the levels of PAR-4, with or without the presence of amphiphilic lipid compounds and optionally employing MEDII conditioned medium. The methods alternatively encompass modulating apoptosis by modulating the intracellular concentration of endogenous lipid second messengers, such as ceramide. |
| FILED | Thursday, September 25, 2003 |
| APPL NO | 10/529115 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446196 | Dong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Kosan Biosciences, Incorporated (Hayward, California) |
| INVENTOR(S) | Steven Dong (San Francisco, California); Daniel V. Santi (San Francisco, California); David C. Myles (Kensington, California); Brian Hearn (San Francisco, California) |
| ABSTRACT | Leptomycin-type compounds according to Formula I wherein R0, R1, R2, R10, R11, R12, R13, R14, and m are as defined herein, exhibit anti-tumor activity. |
| FILED | Wednesday, June 01, 2005 |
| APPL NO | 11/142482 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446526 | Cunningham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Charles H. Cunningham (San Francisco, California); Krishna S. Nayak (Los Angeles, California); John M. Pauly (Stanford, California) |
| ABSTRACT | For in vivo magnetic resonance imaging at high field (≧3 T) it is essential to consider the homogeneity of the active B1 field (B1+), particularly if surface coils are used for RF transmission. A new method is presented for highly rapid B1+ magnitude mapping. It combines the double angle method with a B1-insensitive magnetization-reset sequence such that the choice of repetition time (TR) is independent of T1 and with a multi-slice segmented (spiral) acquisition to achieve volumetric coverage with adequate spatial resolution in a few seconds. |
| FILED | Thursday, December 21, 2006 |
| APPL NO | 11/614798 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446777 | Breneman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Curt Breneman (Troy, New York) |
| ABSTRACT | A method for computing surface descriptors for a closed surface, which are each encoded with a property of the closed surface. A triangulated model of the closed surface is provided that includes a number of triangles. A number of random points within the closed surface are selected. A set of surface descriptors originated from each of the plurality of random points are generated, in parallel, using a ray bouncing algorithm. Each surface descriptor is determined using: a ray length of a ray traced by the ray bouncing algorithm; and an estimated property value at the point of intersection. The estimated property value is calculated using property values corresponding to the vertices of the intersected triangle. It is determined whether a distribution of the sets of surface descriptors converge using a convergence algorithm. The ray bouncing and convergence algorithms are repeated until this distribution is determined to converge. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/949065 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/581 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447595 | Pohlschroder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mechtild Pohlschroder (Philadelphia, Pennsylvania); Jessica C Kissinger (Athens, Georgia); R. Wesley Rose (Glenside, Pennsylvania); Thomas Brueser (Halle, Germany); Kieran Dilks (Collingswood, New Jersey) |
| ABSTRACT | Provided are means for evaluating and identifying putative substrates of the twin arginine translocation (Tat) secretory pathway in Streptomyces and other bacterial species. Also provided, therefore, are simple ways to express, secrete and purify correctly folded heterologous proteins on a large scale using host microorganisms, such as, Streptomyces and the Tat pathway therein. Many of the thus-produced proteins are of significant therapeutic value in the pharmaceutical and biochemical industries, particularly when they can be secreted from the host in fully-folded active form. Accordingly, there are further provided the heterologous proteins produced by the Tat secretion pathway using the foregoing methods, and the computer algorithm used to identify the Tat signal sequence and putative substrates. |
| FILED | Monday, March 17, 2003 |
| APPL NO | 10/507855 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07445027 | Flachsbart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Bruce R. Flachsbart (Champaign, Illinois); Mark A. Shannon (Champaign, Illinois); Paul W. Bohn (Champaign, Illinois); Jonathan V Sweedler (Urbana, Illinois) |
| ABSTRACT | A method of bonding layers to form a structure, comprises curing a first adhesive while squeezing a first layer and a multilayer structure together between a first backing and a second backing. The multilayer structure comprises a substrate and a second layer, and the first adhesive is between and in contact with the first layer and the second layer. Furthermore, the first layer and the second layer each have a thickness of at most 100 μm, and at least one of the first backing and the second backing comprises a first elastic polymer. |
| FILED | Tuesday, March 14, 2006 |
| APPL NO | 11/375525 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Fluid handling 137/803 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445671 | Sunkara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville (Louisville, Kentucky); University of Kentucky (Lexington, Kentucky) |
| INVENTOR(S) | Mahendra Kumar Sunkara (Louisville, Kentucky); Shashank Sharma (Mountain View, California); Burtron H. Davis (Georgetown, Kentucky); Uschi M. Graham (Lexington, Kentucky) |
| ABSTRACT | A method of producing networks of low melting metal oxides such as crystalline gallium oxide comprised of one-dimensional nanostructures. Because of the unique arrangement of wires, these crystalline networks defined as “nanowebs”, “nanowire networks”, and/or “two-dimensional nanowires”. Nanowebs contain wire densities on the order of 109/cm2. A possible mechanism for the fast self-assembly of crystalline metal oxide nanowires involves multiple nucleation and coalescence via oxidation-reduction reactions at the molecular level. The preferential growth of nanowires parallel to the substrate enables them to coalesce into regular polygonal networks. The individual segments of the polygonal network consist of both nanowires and nanotubules of β-gallium oxide. The synthesis of highly crystalline noncatalytic low melting metals such as β-gallium oxide tubes, nanowires, and nanopaintbrushes is accomplished using molten gallium and microwave plasma containing a mixture of monoatomic oxygen and hydrogen. Gallium oxide nanowires were 20-100 nm thick and tens to hundreds of microns long. Transmission electron microscopy (TEM) revealed the nanowires to be highly crystalline and devoid of any structural defects. Results showed that multiple nucleation and growth of gallium oxide nanostructures can occur directly out of molten gallium exposed to appropriate composition of hydrogen and oxygen in the gas phase. The method of producing nanowebs is extendible to other low melting metals and their oxides such as for example: zinc oxide, tin oxide, aluminum oxide, bismuth oxide, and titanium dioxide. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/869489 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445923 | Houtz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Robert L. Houtz (Lexington, Kentucky); David W. Rodgers (Versailles, Kentucky); Lynette M. A. Dirk (Lexington, Kentucky); Mark A. Williams (Lexington, Kentucky) |
| ABSTRACT | This invention relates to the crystal structure of a plant peptide deformylase polypeptide and methods of using the structure to design compounds that modulate the activity of the polypeptide. |
| FILED | Tuesday, October 03, 2006 |
| APPL NO | 11/542989 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/227 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446335 | Kortshagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Uwe Kortshagen (Roseville, Minnesota); Elijah J. Thimsen (Minneapolis, Minnesota); Lorenzo Mangolini (Minneapolis, Minnesota); Ameya Bapat (Minneapolis, Minnesota); David Jurbergs (Austin, Texas) |
| ABSTRACT | Methods and apparatus for producing nanoparticles, including single-crystal semiconductor nanoparticles, are provided. The methods include the step of generating a constricted radiofrequency plasma in the presence of a precursor gas containing precursor molecules to form nanoparticles. Single-crystal semiconductor nanoparticles, including photoluminescent silicon nanoparticles, having diameters of no more than 10 nm may be fabricated in accordance with the methods. |
| FILED | Friday, June 17, 2005 |
| APPL NO | 11/155340 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/51 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446777 | Breneman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Curt Breneman (Troy, New York) |
| ABSTRACT | A method for computing surface descriptors for a closed surface, which are each encoded with a property of the closed surface. A triangulated model of the closed surface is provided that includes a number of triangles. A number of random points within the closed surface are selected. A set of surface descriptors originated from each of the plurality of random points are generated, in parallel, using a ray bouncing algorithm. Each surface descriptor is determined using: a ray length of a ray traced by the ray bouncing algorithm; and an estimated property value at the point of intersection. The estimated property value is calculated using property values corresponding to the vertices of the intersected triangle. It is determined whether a distribution of the sets of surface descriptors converge using a convergence algorithm. The ray bouncing and convergence algorithms are repeated until this distribution is determined to converge. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/949065 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/581 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447209 | Jeffay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina (Chapel Hill, North Carolina) |
| INVENTOR(S) | Kevin Jeffay (Chapel Hill, North Carolina); Felix Hernandez-Campos (Chapel Hill, North Carolina); Frank Donelson Smith (Chapel Hill, North Carolina); Andrew B. Nobel (Chapel Hill, North Carolina) |
| ABSTRACT | Methods, systems, and computer program products are disclosed for determining application-level traffic characteristics in a network based on transport and network layer header information. Transport and network layer header information is collected from packet traffic in a network. Packets are classified to different connections based on the transport and network layer header information. Each connection is modeled using an abstract syntax for characterizing bidirectional interactions between endpoints of each connection and delays between the interactions. Application-level characteristics of the packet traffic are determined based on the modeled connections. Simulated traffic that models application-level traffic behavior in a real network may also be generated by simulating traffic connections based on the modeled connections. |
| FILED | Wednesday, March 09, 2005 |
| APPL NO | 11/075992 |
| ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Multiplex communications 370/392 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447595 | Pohlschroder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mechtild Pohlschroder (Philadelphia, Pennsylvania); Jessica C Kissinger (Athens, Georgia); R. Wesley Rose (Glenside, Pennsylvania); Thomas Brueser (Halle, Germany); Kieran Dilks (Collingswood, New Jersey) |
| ABSTRACT | Provided are means for evaluating and identifying putative substrates of the twin arginine translocation (Tat) secretory pathway in Streptomyces and other bacterial species. Also provided, therefore, are simple ways to express, secrete and purify correctly folded heterologous proteins on a large scale using host microorganisms, such as, Streptomyces and the Tat pathway therein. Many of the thus-produced proteins are of significant therapeutic value in the pharmaceutical and biochemical industries, particularly when they can be secreted from the host in fully-folded active form. Accordingly, there are further provided the heterologous proteins produced by the Tat secretion pathway using the foregoing methods, and the computer algorithm used to identify the Tat signal sequence and putative substrates. |
| FILED | Monday, March 17, 2003 |
| APPL NO | 10/507855 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447614 | Ghaboussi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jamshid Ghaboussi (Urbana, Illinois); Youssef M. A. Hashash (Urbana, Illinois); David Pecknold (Urbana, Illinois) |
| ABSTRACT | A method for modeling material behavior includes using empirical three dimensional non-uniform stress and strain data to train a self-organizing computational model such as a neural network. A laboratory device for measuring non-uniform stress and strain data from material includes an enclosure with an inclusion in it. As the enclosure is compressed, the inclusion induces a non-uniform state of stress and strain. A field testing device includes a body having a moveable section. When the body is inserted in a material and the moveable section moved, a non-uniform state of stress and strain can be characterized. |
| FILED | Wednesday, April 09, 2003 |
| APPL NO | 10/409882 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07444980 | Cavanagh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Mark S. Cavanagh (Bloomington, Illinois); Roger L. Urven, Jr. (Colona, Illinois); Keith E. Lawrence (Peoria, Illinois) |
| ABSTRACT | A direct injection fuel injector includes a nozzle tip having a plurality of passages allowing fluid communication between an inner nozzle tip surface portion and an outer nozzle tip surface portion and directly into a combustion chamber of an internal combustion engine. A first group of the passages have inner surface apertures located substantially in a first common plane. A second group of the passages have inner surface apertures located substantially in at least a second common plane substantially parallel to the first common plane. The second group has more passages than the first group. |
| FILED | Tuesday, May 22, 2007 |
| APPL NO | 11/802289 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/299 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445658 | Armstrong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Donn Reynolds Armstrong (Waukesha, Wisconsin); Stanley R. Borys (Elmhurst, Illinois); Richard P. Anderson (Clarendon Hills, Illinois) |
| ABSTRACT | A method of producing a non-metal element or a metal or an alloy thereof from a halide or mixtures thereof. The halide or mixtures thereof are contacted with a stream of liquid alkali metal or alkaline earth metal or mixtures thereof in sufficient quantity to convert the halide to the non-metal or the metal or alloy and to maintain the temperature of the reactants at a temperature lower than the lesser of the boiling point of the alkali or alkaline earth metal at atmospheric pressure or the sintering temperature of the produced non-metal or metal or alloy. A continuous method is disclosed, particularly applicable to titanium. |
| FILED | Friday, April 19, 2002 |
| APPL NO | 10/125942 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/255 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445926 | Mathies et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard A. Mathies (Moraga, California); William H. Grover (Berkeley, California); Alison Skelley (Berkeley, California); Eric Lagally (Oakland, California); Chung N. Liu (Albany, California) |
| ABSTRACT | Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques. |
| FILED | Monday, December 29, 2003 |
| APPL NO | 10/750533 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446314 | Friedrich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Stephan Friedrich (San Jose, California); Thomas R. Niedermayr (Oakland, California); Simon E. Labov (Berkeley, California) |
| ABSTRACT | Superconducting Gamma-ray and fast-neutron spectrometers with very high energy resolution operated at very low temperatures are provided. The sensor consists of a bulk absorber and a superconducting thermometer weakly coupled to a cold reservoir, and determines the energy of the incident particle from the rise in temperature upon absorption. A superconducting film operated at the transition between its superconducting and its normal state is used as the thermometer, and sensor operation at reservoir temperatures around 0.1 K reduces thermal fluctuations and thus enables very high energy resolution. Depending on the choice of absorber material, the spectrometer can be configured either as a Gamma-spectrometer or as a fast-neutron spectrometer. |
| FILED | Friday, September 30, 2005 |
| APPL NO | 11/240675 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/336.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07446324 — Methods utilizing scanning probe microscope tips and products thereof or produced thereby
| US 07446324 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Richard Piner (Des Plaines, Illinois); Seunghun Hong (Seoul, South Korea) |
| ABSTRACT | The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a “pen,” a solid-state substrate (e.g., gold) as “paper,” and molecules with a chemical affinity for the solid-state substrate as “ink.” Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds. |
| FILED | Tuesday, September 28, 2004 |
| APPL NO | 10/951031 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447096 | Riekels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | James E. Riekels (New Hope, Minnesota); Samuel Schlesinger (Aventura, Florida) |
| ABSTRACT | A non-volatile memory and a method of refreshing a memory are described. The method includes allowing an external system to control refreshing operations within the memory. The memory may generate a refresh request signal and transmit the refresh request signal to the external system. When the external system finds an available time to process the refresh request, the external system acknowledges the refresh request and transmits a refresh acknowledge signal to the memory. The memory may also comprise a page register for reading and rewriting a data state back to the memory. The page register may comprise latches in lieu of supplemental non-volatile storage elements, thereby conserving real estate within the memory. |
| FILED | Thursday, January 04, 2007 |
| APPL NO | 11/619677 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447595 | Pohlschroder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mechtild Pohlschroder (Philadelphia, Pennsylvania); Jessica C Kissinger (Athens, Georgia); R. Wesley Rose (Glenside, Pennsylvania); Thomas Brueser (Halle, Germany); Kieran Dilks (Collingswood, New Jersey) |
| ABSTRACT | Provided are means for evaluating and identifying putative substrates of the twin arginine translocation (Tat) secretory pathway in Streptomyces and other bacterial species. Also provided, therefore, are simple ways to express, secrete and purify correctly folded heterologous proteins on a large scale using host microorganisms, such as, Streptomyces and the Tat pathway therein. Many of the thus-produced proteins are of significant therapeutic value in the pharmaceutical and biochemical industries, particularly when they can be secreted from the host in fully-folded active form. Accordingly, there are further provided the heterologous proteins produced by the Tat secretion pathway using the foregoing methods, and the computer algorithm used to identify the Tat signal sequence and putative substrates. |
| FILED | Monday, March 17, 2003 |
| APPL NO | 10/507855 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07445859 | Vamos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Eugene Vamos (Somerville, Massachusetts); Subbarao Surampudi (Glendora, California); Sekharipuram R. Narayanan (Altadena, California); Harvey A. Frank (Encino, California); Gerald Halpert (Pasadena, California); George A. Olah (Beverly Hills, California); G. K. Surya Prakash (Hacienda Heights, California) |
| ABSTRACT | A liquid organic, fuel cell is provided which employs a solid electrolyte membrane. An organic fuel, such as a methanol/water mixture, is circulated past an anode of a cell while oxygen or air is circulated past a cathode of the cell. The cell solid electrolyte membrane is preferably fabricated from Nafion™. Additionally, a method for improving the performance of carbon electrode structures for use in organic fuel cells is provided wherein a high surface-area carbon particle/Teflon™-binder structure is immersed within a Nafion™/methanol bath to impregnate the electrode with Nafion™. A method for fabricating an anode for use in a organic fuel cell is described wherein metal alloys are deposited onto the electrode in an electro-deposition solution containing perfluorooctanesulfonic acid. A fuel additive containing perfluorooctanesulfonic acid for use with fuel cells employing a sulfuric acid electrolyte is also disclosed. New organic fuels, namely, trimethoxymethane, dimethoxymethane, and trioxane are also described for use with either conventional or improved fuel cells. |
| FILED | Thursday, May 27, 2004 |
| APPL NO | 10/857587 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07445926 | Mathies et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard A. Mathies (Moraga, California); William H. Grover (Berkeley, California); Alison Skelley (Berkeley, California); Eric Lagally (Oakland, California); Chung N. Liu (Albany, California) |
| ABSTRACT | Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques. |
| FILED | Monday, December 29, 2003 |
| APPL NO | 10/750533 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446044 | Kaul et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Anupama B. Kaul (Arcadia, California); Eric W. Wong (Los Angeles, California); Richard L. Baron (Verdugo City, California); Larry Epp (Pasadena, California) |
| ABSTRACT | Switches having an in situ grown carbon nanotube as an element thereof, and methods of fabricating such switches. A carbon nanotube is grown in situ in mechanical connection with a conductive substrate, such as a heavily doped silicon wafer or an SOI wafer. The carbon nanotube is electrically connected at one location to a terminal. At another location of the carbon nanotube there is situated a pull electrode that can be used to elecrostatically displace the carbon nanotube so that it selectively makes contact with either the pull electrode or with a contact electrode. Connection to the pull electrode is sufficient to operate the device as a simple switch, while connection to a contact electrode is useful to operate the device in a manner analogous to a relay. In various embodiments, the devices disclosed are useful as at least switches for various signals, multi-state memory, computational devices, and multiplexers. |
| FILED | Tuesday, September 19, 2006 |
| APPL NO | 11/523273 |
| ART UNIT | 2823 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/684 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446459 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | National Institute of Aerospace Associates (Hampton, Virginia); The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Tian-Bing Xu (Hampton, Virginia); Xiaoning Jiang (State College, Pennsylvania); Ji Su (Yorktown, Virginia); Paul W. Rehrig (Marlborough, Pennsylvania); Wesley S. Hackenberger (State College, Pennsylvania) |
| ABSTRACT | A hybrid piezoelectric energy harvesting transducer system includes: (a) first and second symmetric, pre-curved piezoelectric elements mounted separately on a frame so that their concave major surfaces are positioned opposite to each other; and (b) a linear piezoelectric element mounted separately on the frame and positioned between the pre-curved piezoelectric elements. The pre-curved piezoelectric elements and the linear piezoelectric element are spaced from one another and communicate with energy harvesting circuitry having contact points on the frame. The hybrid piezoelectric energy harvesting transducer system has a higher electromechanical energy conversion efficiency than any known piezoelectric transducer. |
| FILED | Thursday, July 13, 2006 |
| APPL NO | 11/486200 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/339 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07446860 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan W. Campbell (Madison, Alabama); David L. Lehner (Huntsville, Alabama); Larry L. Smalley (Huntsville, Alabama); Molly C. Smith, legal representative (Madison, Alabama); Alvin J. Sanders (Knoxville, Tennessee); Dennis Duncan Earl (Knoxville, Tennessee); Stephen W. Allison (Knoxville, Tennessee) |
| ABSTRACT | A method and system for determining range to a target are provided. A beam of electromagnetic energy is transmitted through an aperture in an opaque screen such that a portion of the beam passes through the aperture to generate a region of diffraction that varies as a function of distance from the aperture. An imaging system is focused on a target plane in the region of diffraction with the generated image being compared to known diffraction patterns. Each known diffraction pattern has a unique value associated therewith that is indicative of a distance from the aperture. A match between the generated image and at least one of the known diffraction patterns is indicative of a distance between the aperture and target plane. |
| FILED | Monday, September 18, 2006 |
| APPL NO | 11/527648 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optics: Measuring and testing 356/4.30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07445671 | Sunkara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville (Louisville, Kentucky); University of Kentucky (Lexington, Kentucky) |
| INVENTOR(S) | Mahendra Kumar Sunkara (Louisville, Kentucky); Shashank Sharma (Mountain View, California); Burtron H. Davis (Georgetown, Kentucky); Uschi M. Graham (Lexington, Kentucky) |
| ABSTRACT | A method of producing networks of low melting metal oxides such as crystalline gallium oxide comprised of one-dimensional nanostructures. Because of the unique arrangement of wires, these crystalline networks defined as “nanowebs”, “nanowire networks”, and/or “two-dimensional nanowires”. Nanowebs contain wire densities on the order of 109/cm2. A possible mechanism for the fast self-assembly of crystalline metal oxide nanowires involves multiple nucleation and coalescence via oxidation-reduction reactions at the molecular level. The preferential growth of nanowires parallel to the substrate enables them to coalesce into regular polygonal networks. The individual segments of the polygonal network consist of both nanowires and nanotubules of β-gallium oxide. The synthesis of highly crystalline noncatalytic low melting metals such as β-gallium oxide tubes, nanowires, and nanopaintbrushes is accomplished using molten gallium and microwave plasma containing a mixture of monoatomic oxygen and hydrogen. Gallium oxide nanowires were 20-100 nm thick and tens to hundreds of microns long. Transmission electron microscopy (TEM) revealed the nanowires to be highly crystalline and devoid of any structural defects. Results showed that multiple nucleation and growth of gallium oxide nanostructures can occur directly out of molten gallium exposed to appropriate composition of hydrogen and oxygen in the gas phase. The method of producing nanowebs is extendible to other low melting metals and their oxides such as for example: zinc oxide, tin oxide, aluminum oxide, bismuth oxide, and titanium dioxide. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/869489 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07447310 | Koç et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Çetin K. Koç (Corvallis, Oregon); Serdar S. Erdem (Istanbul, Turkey) |
| ABSTRACT | Multi-precision multiplication methods over GF(2m) include representing a first polynomial and a second polynomial as an array of n words. A recursive algorithm may be used to iteratively decompose the multiplication into a weighted sum of smaller subproducts. When the size of the smaller subproducts is less than or equal to a predetermined size, a nonrecursive algorithm may be used to complete the multiplication. The nonrecursive algorithm may be optimized to efficiently perform the bottom-end multiplication. For example, pairs of redundant subproducts can be identified and excluded from the nonrecursive algorithm. Moreover, subproducts having weights in a special form may be efficiently calculated by a process that involves storing and reusing intermediate calculations. |
| FILED | Wednesday, August 06, 2003 |
| APPL NO | 10/636326 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Cryptography 380/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07446131 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | LinShu Liu (Wyndmoor, Pennsylvania); Marshall L. Fishman (Lansdale, Pennsylvania); Kevin B. Hicks (Malvern, Pennsylvania) |
| ABSTRACT | A porous polymeric matrix containing at least one natural polymer and at least one synthetic polymer and optionally at least one cation. Furthermore, a method of making a porous polymeric matrix involving mixing at least one natural polymer and inorganic salts with a solution comprising at least one solvent and at least one synthetic polymer to form a slurry, casting the slurry in a mold and removing the solvent to form solid matrices, immersing the solid matrices in deionized water to allow natural polymer cross-linking and pore creation to occur simultaneously, and drying the matrices to create a porous polymeric matrix; wherein the matrix contains a cation. Also, a method of making a porous polymeric matrix, involving mixing at least one natural polymer in an aqueous solvent and mixing at least one synthetic polymer in an organic solvent, combining the mixtures and casting in a mold, and separately removing said aqueous solvent and said organic solvent to form a porous polymeric matrix; wherein the porous polymeric matrix does not contain a cation. |
| FILED | Tuesday, February 15, 2005 |
| APPL NO | 11/058034 |
| ART UNIT | 1796 — Semiconductors/Memory |
| CURRENT CPC | Synthetic resins or natural rubbers 521/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07445752 | Harms et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
| INVENTOR(S) | Michael R. Harms (Mendota Heights, Minnesota); William Bedingham (Woodbury, Minnesota); Christopher R. Kokaisel (Mendota Heights, Minnesota); Barry W. Robole (Woodville, Wisconsin); Kenneth B. Wood (St. Paul, Minnesota) |
| ABSTRACT | Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas. The carriers may be used to apply selective compression to the sample processing devices. |
| FILED | Friday, August 27, 2004 |
| APPL NO | 10/929044 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/58 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Library of Congress (LOC)
| US D579940 | Pepin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Technologies Humanware Canada, Inc. (Québec, Canada); Wisconsin Alumni Research Foundation (Madison, Wisconsin); United States Library of Congress (Washington, District of Columbia) |
| INVENTOR(S) | Gilles Pepin (St-Charles de Drummondville, Canada); Alain Paré (Kirkland, Canada); Dominic R. Labbé (McMasterville, Canada); Gerard M. Chevalier (Edmonton, Canada); Joseph A. Juratovac (Columbus, Ohio); Jeffrey R. Held (Columbus, Ohio); Jeffrey Michael Witt (Baltimore, Maryland); Gregg Charles Vanderheiden (Madison, Wisconsin); David Paul Kelso (Madison, Wisconsin); Frank Kurt Cylke (Great Falls, Virginia); Jean Marie Moss (Glendale, Maryland); Michael Gilbert Katzmann (Washington, District of Columbia); Robert Edward Fistick (Charlotte Hall, Maryland); Michael Montfort Moodie (Bethesda, Maryland); Alice Kathryn Baker (Washington, Washington); Donald Lee Pieper (Arroyo Grande, California) |
| ABSTRACT | |
| FILED | Thursday, March 15, 2007 |
| APPL NO | 29/273874 |
| ART UNIT | 2911 — Design |
| CURRENT CPC | Recording, communication, or information retrieval equipment D14/435 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07447595 | Pohlschroder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mechtild Pohlschroder (Philadelphia, Pennsylvania); Jessica C Kissinger (Athens, Georgia); R. Wesley Rose (Glenside, Pennsylvania); Thomas Brueser (Halle, Germany); Kieran Dilks (Collingswood, New Jersey) |
| ABSTRACT | Provided are means for evaluating and identifying putative substrates of the twin arginine translocation (Tat) secretory pathway in Streptomyces and other bacterial species. Also provided, therefore, are simple ways to express, secrete and purify correctly folded heterologous proteins on a large scale using host microorganisms, such as, Streptomyces and the Tat pathway therein. Many of the thus-produced proteins are of significant therapeutic value in the pharmaceutical and biochemical industries, particularly when they can be secreted from the host in fully-folded active form. Accordingly, there are further provided the heterologous proteins produced by the Tat secretion pathway using the foregoing methods, and the computer algorithm used to identify the Tat signal sequence and putative substrates. |
| FILED | Monday, March 17, 2003 |
| APPL NO | 10/507855 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07445799 | Sarangapani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ICET, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Shantha Sarangapani (Walpole, Massachusetts); Quoc T. Truong (Hyde Park, Massachusetts) |
| ABSTRACT | An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same. |
| FILED | Thursday, June 21, 2001 |
| APPL NO | 09/886663 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/618 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07445904 | Südhof et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas C Südhof (Dallas, Texas); Bernd Stahl (72076 Tuebingen, Germany); Soenke Tobaben (37075 Goettingen, Germany) |
| ABSTRACT | The present invention relates to in vitro and in vivo assays for the identification of agents that are useful in the treatment of neurodegenerative diseases that are associated with defects in protein folding. The present further relates to in vitro and in vivo assays for the identification of agents that contribute to the neurodegenerative processes which occur in these diseases. The present invention also relates to in vitro and in vivo models of neurodegenerative diseases. These assays and models will be useful in further understanding the pathogenesis of various neurodegenerative diseases in which defects in protein folding have been implicated, in identifying additional endogenous or environmental factors that contribute to the etiologies of these diseases, and in developing effective therapies for the prevention and/or treatment of these diseases. |
| FILED | Thursday, September 26, 2002 |
| APPL NO | 10/255989 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 04, 2008.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20081104.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page