FedInvent™ Patents

Patent Details for Tuesday, November 25, 2008 

This page was updated on Monday, March 27, 2023 at 01:00 AM GMT

Department of Defense (DOD) 

US 07455495 Leogrande et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) John A. Leogrande (West Hartford, Connecticut);  Peter L. Jalbert (Granby, Connecticut);  C. Bruce Wood (Ellington, Connecticut);  Matthew J. Schryver (Wethersfield, Connecticut)
ABSTRACT A system and method for determining thermal growth of motor or engine parts to thereupon control the clearance of motor or engine fan blades is disclosed herein. In addition, a system and method for monitoring the health of a turbine engine, its components and sub-components is also described herein. The system(s) and method(s) described herein permit continuous monitoring during the life of the engine for radial clearances and blade and rotor vibration problems, which will assist in correcting and retaining performance for a longer on-wing time in operation. In addition, inconsistent engine-to-engine performance variations due to component tolerances, engine operation characteristics, and operation during extremes in ambient temperatures can be eliminated or significantly minimized when employing the system(s) and method(s) described herein.
FILED Tuesday, August 16, 2005
APPL NO 11/204490
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/1
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US 07455565 Machuca et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Francisco Machuca (San Francisco, California);  Zhi Liu (Palo Alto, California)
ABSTRACT Improved photocathodes are provided by a fabrication method including steps of wet chemically cleaning the photocathode emission surface (to reduce the level of cleaning-induced surface damage), two stage heat treatment (to complete the cleaning without desorbing nitrogen from the emission surface), followed by activation with Cs only, as opposed to Cs—O. The resulting photocathodes have improved performance (lifetime, brightness, efficiency) compared to conventional photocathodes, and are thus attractive candidates for demanding photocathode applications.
FILED Thursday, March 16, 2006
APPL NO 11/378133
ART UNIT 2889 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Electric lamp or space discharge component or device manufacturing
445/51
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US 07455620 Frykman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Peter N. Frykman (Natick, Massachusetts);  Everett A. Harman (Natick, Massachusetts);  Michael E. LaFiandra (Merrimack, New Hampshire)
ABSTRACT A method for interpreting data representing forces and torques exerted by a right and left foot on a first and second plate treadmill to determine forces and torques exerted on the right and left foot over a specified period of time. A plurality of signals is preferably analyzed to produce data readings from the first and second plates to determine an occurrence of feet contact on the plates and feet departure from the plates. The data from the signals is then separated into a side A dataset and a side B dataset. Each of the datasets is then matched to one of the individual's feet. The resulting determination of forces and torques exerted on the feet provides a more complete analysis of an individual's progress during injury or rehabilitation.
FILED Tuesday, April 06, 2004
APPL NO 10/817915
ART UNIT 3764 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Exercise devices
482/1
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US 07455757 Oh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Soojin Oh (Chapel Hill, North Carolina);  Otto Z. Zhou (Chapel Hill, North Carolina)
ABSTRACT A method for depositing a patterned coating of a nanostructure material onto a substrate includes: (1) forming a solution or suspension of containing the nanostructure material; (2) masking at least a portion of at least one surface of the substrate (3) immersing electrodes in the solution, the substrate upon which the nanostructure material is to be deposited acting as one of the electrodes or is electrically connected to at least one electrode; (4) applying a direct and/or alternating current electrical field between the two electrodes for a certain period of time thereby causing the nanostructure materials in the solution to migrate toward and attach themselves to the substrate electrode; and (5) subsequent optional processing.
FILED Thursday, July 10, 2003
APPL NO 10/615842
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical and wave energy
24/490
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US 07455840 Romesberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California);  Achaogen, Inc. (San Francisco, California)
INVENTOR(S) Floyd Romesberg (La Jolla, California);  Nathaniel E. David (San Francisco, California);  Ryan Cirz (San Diego, California)
ABSTRACT The present invention provides methods and compositions for said inhibition of drug resistance. In one embodiment, said invention provides methods and compositions for said inhibition of antibiotic resistance. The invention generally involves said administration of achaogens, agents that inhibit said mutational process, to inhibit said evolution of drug resistance. Also, described herein are compositions that are suitable for use as achaogens.
FILED Friday, November 19, 2004
APPL NO 10/994215
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/164.100
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US 07455927 DiSalvo, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Francis J. DiSalvo, Jr. (Ithaca, New York);  Hector D. Abruna (Ithaca, New York)
ABSTRACT The invention is directed to intermetallic compounds for use as catalysts for chemical reactions and catalytic systems. The structure of ordered intermetallic compounds enables such compounds to function as highly efficient catalysts. The ordered intermetallic compounds may be used to catalyze reactions in fuel cells (e.g., hydrogen fuel cells), amongst numerous other applications.
FILED Tuesday, July 29, 2003
APPL NO 10/630237
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/40
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US 07455975 Henkens et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) ESA Biosciences, Inc. (Chelmsford, Massachusetts)
INVENTOR(S) Robert W. Henkens (Beaufort, North Carolina);  John P. O'Daly (Carrboro, North Carolina);  Marek Wojciechowski (Cary, North Carolina);  Honghua Zhang (San Diego, California);  Najih Naser (Orlando, Florida);  R. Michael Roe (Apex, North Carolina);  Thomas N. Stewart (Durham, North Carolina);  Deborah M. Thompson (Raleigh, North Carolina);  Rebecca Sundseth (Durham, North Carolina);  Steven E. Wegner (Chapel Hill, North Carolina)
ABSTRACT An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.
FILED Wednesday, January 03, 2007
APPL NO 11/619232
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07455994 Hevey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Michael C. Hevey (Frederick, Maryland);  Diane I. Negley (Frederick, Maryland);  Peter Pushko (Frederick, Maryland);  Jonathan F. Smith (Sabillasville, Maryland);  Alan L. Schmaljohn (Frederick, Maryland)
ABSTRACT Using the MBGV GP, NP, and virion proteins, a method and composition for use in inducing an immune response which is protective against infection with MBGV in nonhuman primates is described.
FILED Wednesday, July 12, 2006
APPL NO 11/485158
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.300
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US 07456027 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Banyan Biomarkers, Inc. (Alachua, Florida)
INVENTOR(S) Kevin Ka-Wang Wang (Gainesville, Florida);  Ronald Hayes (Gainesville, Florida);  Ming Chen Liu (Gainesville, Florida);  Monika Oli (Gainesville, Florida)
ABSTRACT The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.
FILED Friday, April 15, 2005
APPL NO 11/106932
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Analytical and immunological testing
436/503
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US 07456122 Rhodes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) CeraNova Corporation (Marlborough, Massachusetts)
INVENTOR(S) William H. Rhodes (Lexington, Massachusetts);  Mark V. Parish (Hopkinton, Massachusetts);  Marina R. Pascucci (Worcester, Massachusetts)
ABSTRACT Polycrystalline alumina and methods for manufacturing polycrystalline alumina exhibiting improved transmission in the infrared region. In one embodiment, the percent real in-line transmittance is within about 2% of sapphire at selected wavelengths. In one or more embodiments, polycrystalline articles exhibit improved mechanical properties such as thermal shock resistance and hardness, which may find use in armor applications.
FILED Friday, September 30, 2005
APPL NO 11/240069
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions: Ceramic
51/153
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US 07456154 Soreq et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, Israel)
INVENTOR(S) Hermona Soreq (Jerusalem, Israel);  Jackilynne Seidman, legal representative (Gush Etzion, Israel);  Tama Evron (Mevasseret Zion, Israel)
ABSTRACT The invention relates to an antisense oligonucleotide targeted to the coding region of the human acetylcholinesterase (AChE), which selectively suppresses the AChE-R isoform of the enzyme. The antisense oligonucleotide is intended for use in the treatment and/or prevention of neuromuscular disorders, preferably myasthenia gravis. In addition, it can penetrate the blood-brain barrier (BBB) and destroy AChE-R within central nervous system neurons, while also serving as a carrier to transport molecules across the BBB.
FILED Wednesday, February 01, 2006
APPL NO 11/346145
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07456295 Irvin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David J. Irvin (Ridgecrest, California);  David L. Witker (Bay City, Michigan);  John D. Stenger-Smith (Ridgecrest, California);  Jennifer A. Irvin (Ridgecrest, California)
ABSTRACT The present invention demonstrates the synthesis of a new pyrazole-containing monomer by means of an easily implemented two-step process. This monomer can be electropolymerized to yield a stable n-doping polymer that may easily be electrochemically characterized. It is demonstrated that the electrochemical behavior of the polymer films produced is dependent upon the conditions applied during electrodeposition. Films deposited by cycling only at relatively positive potentials (0 to 2000 mV) show less intense n-doping responses than those films obtained by scanning the applied potential throughout a wider range (−2000 mV to 2000 mV). It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope of the claims.
FILED Saturday, November 25, 2006
APPL NO 11/645257
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
548/365.700
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US 07456383 Kim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh (Pittsburgh, Pennsylvania)
INVENTOR(S) Hong Koo Kim (Pittsburgh, Pennsylvania);  Zhijun Sun (Pittsburgh, Pennsylvania);  Yun Suk Jung (Pittsburgh, Pennsylvania)
ABSTRACT A nanostructured optical device includes a metal film or a plurality of metal islands having an array of a plurality of openings having a width that is less than at least one first predetermined wavelength of incident radiation to be provided onto the film or the islands. The metal film or islands are configured such that the incident radiation is resonant with at least one plasmon mode on the metal film or metal islands.
FILED Thursday, July 22, 2004
APPL NO 10/566946
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/226
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US 07456525 Rhodes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Sean Rhodes (Carlisle, Canada);  Robert G. Czychun (Brighton, Canada);  Dikran Yaldizciyan (Mississauga, Canada)
ABSTRACT A packaged power supply device (10) is configured to output multiple supply voltages, which are converted from a single input voltage (VIN). The packaged power supply device may can be configured as a DC/DC converter, which is operable to output each of the output supply voltages in a sequential manner, in accordance's with power up sequencing requirements of a processor-based system. The sequential output supply voltages may include: a fixed core supply voltage, a programmable core supply voltage, an input/output (I/O) supply voltage, and a logic supply voltage. These output supply voltages might be converted from an input voltage VIN, which has a wide continuous operational range (e.g., 14-50 VDC).
FILED Friday, July 09, 2004
APPL NO 10/887939
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electrical transmission or interconnection systems
37/85
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US 07456702 Keefe et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) George Andrew Keefe (Cortlandt Manor, New York);  Roger Hilsen Koch (Amawalk, New York);  Frank P Milliken, Jr. (Tarrytown, New York);  James R. Rozen (Peekskill, New York)
ABSTRACT A low pass filter having a coaxial structure of an inner conductor, an outer conductor and a metal powder composite interposed between the inner and outer conductor. Embodiments include a 50Ω characteristic impedance. The metal powder can be bronze, copper or other metals, mixed in an epoxy carrier.
FILED Monday, July 10, 2006
APPL NO 11/456351
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/99.S00
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US 07456711 Goldsmith
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) Memtronics Corporation (Plano, Texas)
INVENTOR(S) Charles L. Goldsmith (Plano, Texas)
ABSTRACT An apparatus and a method are provided for electronically tuning cavity filters. A tunable cavity comprises at least two pieces of material, such as metal plates or metal traces, and MEMS circuitry interconnecting the pieces of material. Multiple tunable cavities can be combined to create a tunable cavity filter. In one embodiment, a waveguide cavity filter comprises a metal insert attached to a substrate. At least two pieces of material and MEMS circuitry reside within the cavities produced by the metal insert. The MEMS circuitry can be controlled to connect or disconnect the pieces of material, which alters the electric and magnetic fields inside the cavities. In another embodiment, a MEMS positioner inside the cavity filter can physically deform or move a piece of material within the cavity. By altering the electric and magnetic fields within the cavities the resonant frequency of the cavity filter can be tuned.
FILED Wednesday, November 09, 2005
APPL NO 11/270768
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/209
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US 07456722 Eaton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Deran S. Eaton (Waldorf, Maryland);  Robert M. Daily (Swan Point, Maryland)
ABSTRACT A programmable transformer incorporating windings embedded in a thin film substrate. The windings are flat wire traces embedded into the substrate, primary on one side and secondary on the other. The secondary windings may be planar or different coils spatially arrayed throughout a thickness of the substrate. The secondary winding may include multiple tap points, effectively providing multiple secondary coils referenced to the single primary coil. Each tap point is bridged to a field effect or CMOS transistor path by which a digital controls permit dynamic adjustment of the turns ratio. The final secondary output depends on the activated transistor paths. Multiple secondary outputs from a single secondary coil and a digitally programmable turns ratio are available aspects.
FILED Thursday, September 27, 2007
APPL NO 11/973976
ART UNIT 2832 — Semiconductors/Memory
CURRENT CPC
Inductor devices
336/200
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US 07457198 Stein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Scientific Solutions, Inc. (Nashua, New Hampshire);  The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Peter Jonathan Stein (Hollis, New Hampshire);  Amy Vandiver (Bedford, New Hampshire);  Michael Richard Birmann (Arlington, Massachusetts);  John Timothy Wood (Nashua, New Hampshire);  Joseph Steven Johnson (Clifton, Virginia)
ABSTRACT A method for detecting an object in a body of water by generating a plurality of signals and applying each signal to a separate submerged sonar node that is a part of an array of sonar nodes.
FILED Friday, March 31, 2006
APPL NO 11/396080
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/151
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US 07457338 Mawst et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Luke J. Mawst (Sun Prairie, Wisconsin);  Nelson Tansu (Bethlehem, Pennsylvania);  Jeng-Ya Yeh (Portland, Oregon)
ABSTRACT In accordance with the present invention, GaAs-based optoelectronic devices have an active region that includes a well layer composed of a compressively-strained semiconductor that is free, or substantially free, of nitrogen disposed between two barrier layers composed of a nitrogen- and indium-containing semiconductor.
FILED Wednesday, April 19, 2006
APPL NO 11/406834
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/43.10
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US 07457487 Miller et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) David A. B. Miller (Stanford, California);  Yu-Hsuan Kuo (National Taiwan, Taiwan);  James S. Harris, Jr. (Stanford, California)
ABSTRACT SiGe quantum wells where the well material has a lowest conduction band energy minimum at k=0 (the Γ point of the first Brillouin zone) are provided. Quantum well structures that satisfy this condition have “Kane-like” bands at and near k=0 which can provide physical effects useful for various device applications, especially optical modulators. In the Si1-xGex material system, this condition on the band structure is satisfied for x greater than about 0.7. The quantum well barrier composition may or may not have Kane-like bands. Embodiments of the invention having a surface parallel configuration are especially suitable for use in fiber coupled devices. Such surface parallel devices have light propagating in the plane of the quantum wells, in a device geometry that is preferably not single-mode waveguided.
FILED Tuesday, September 19, 2006
APPL NO 11/524530
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/2
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US 07457489 Sayyah
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Keyvan Sayyah (Santa Monica, California)
ABSTRACT In one implementation, a method is provided for frequency tuning of a photonic oscillator. The method includes supplying an optical signal, for example laser light, which is modulated, delayed, and then converted to an electrical signal. The electrical signal is amplified, and used in modulating the optical signal. With this implementation, the frequency of the an output signal of the photonic oscillator is shifted by adjusting a bias voltage of the amplifier. In some implementations, shifting the frequency of the output signal further includes using a frequency lock loop circuit. In some implementations, shifting the frequency of an output signal of the photonic oscillator further comprises adjusting at least one of an phase shifter in series with the amplifier, an optical fiber stretcher, or a bias voltage of a second amplifier.
FILED Wednesday, January 04, 2006
APPL NO 11/325913
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/14
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US 07457491 Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Ray T. Chen (Austin, Texas);  Chulchae Chol (Austin, Texas)
ABSTRACT The present invention provides a system, method and apparatus for improved electrical-to-optical transmitters (100) disposed within printed circuit boards (104). The heat sink (110, 200) is a thermal conductive material disposed within a cavity (102) of the printed circuit board (104) and is thermally coupled to a bottom surface (112) of the electrical-to-optical transmitter (100). A portion of the thermal conductive material extends approximately to an outer surface (120, 122 or 124) of a layer (114, 116 or 118) of the printed circuit board (104). The printed circuit board may comprise a planarized signal communications system or an optoelectronic signal communications system. In addition, the present invention provides a method for fabricating the heat sink wherein the electrical-to-optical transmitter disposed within a cavity of the printed circuit board is fabricated. New methods for flexible waveguides and micro-mirror couplers are also provided.
FILED Thursday, September 21, 2006
APPL NO 11/524576
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Optical waveguides
385/14
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US 07457501 Ptasinski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joanna N. Ptasinski (San Diego, California);  J. Scott Rodgers (San Diego, California);  Stephen D. Russell (San Diego, California)
ABSTRACT A technique for coupling electromagnetic energy into an aperture smaller than the wavelength of the electromagnetic energy desired to be coupled is disclosed.
FILED Monday, October 16, 2006
APPL NO 11/586746
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Optical waveguides
385/129
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US 07457803 Robusto et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John D. Robusto (Herndon, Virginia);  Greg R. McBroome (Aurora, Colorado)
ABSTRACT Improved method involving a series of unique steps for progressively and selectively processing data relative to a multiterminal computer network for storing, analizing and periodically upgrading stored data where the network is made up of one or more user terminals, an n-dimensional multicell memory, an electronically transportable metafile structure of ranked/indexed commands for any terminal user, a common metafile interface interchange agreement and an encoded access arrangement. By reason of each metafile structure being arranged between the interface interchange agreement and any user terminal; and by reason of the encoded access arrangement being arranged between the memory and the interchange arrangement, controlled and authorized access by any terminal user is maintained for reading, interpreting, adding, combining, modifying, etc. any data in the network whether data is from the memory, interchange arrangement or input from a user terminal.
FILED Friday, November 08, 1996
APPL NO 08/747799
ART UNIT 2776 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Database and file management or data structures
77/10
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US 07457860 Shang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Palo Alto Research Center, Incorporated (Palo Alto, California)
INVENTOR(S) Yi Shang (Columbia, Missouri);  Wheeler Ruml (Palo Alto, California)
ABSTRACT Disclosed herein is a method for deriving node localization information within communication networks having a plurality of nodes, which are separated by node paths. The method includes estimating the shortest path between multiple pairs of nodes in the network and constructing a matrix encompassing the estimated shortest paths. Multidimensional scaling is then applied to the matrix and the largest eigenvectors of the transformed matrix are identified. From this is constructed a relative map of the location of the pairs of nodes within the network by utilization of the eigenvectors.
FILED Thursday, October 09, 2003
APPL NO 10/682754
ART UNIT 2144 — Graphical User Interface and Document Processing
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/223
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457922 Shen
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Xiaowei Shen (Hopewell Junction, New York)
ABSTRACT In a multiprocessor non-uniform cache architecture system, multiple CPU cores shares one non-uniform cache that can be partitioned into multiple cache portions with varying access latencies. A placement prediction mechanism predicts whether a cache line should remain in a cache portion or migrate to another cache portion. The prediction mechanism maintains one or more prediction counters for each cache line. A prediction counter can be incremented or decremented by a constant or a variable determined by some runtime information, or set to its maximum or minimum value. An effective placement prediction mechanism can reduce average access latencies without causing cache thrashing among cache portions.
FILED Saturday, November 20, 2004
APPL NO 10/993784
ART UNIT 2189 — Graphical User Interface and Document Processing
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/137
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US 07457926 Shen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Xiaowei Shen (Hopewell Junction, New York);  Yefim Shuf (Millwood, New York);  Peter F. Sweeney (Spring Valley, New York)
ABSTRACT Systems and methods for cache replacement monitoring (CRM) are provided. The system includes a monitored cache comprising a monitored cache line set, the monitored cache line set comprising at least one cache line capable of holding data of a monitored address; and a CRM mechanism operatively associated with the monitored cache. The CRM mechanism collects CRM information for the monitored address. The method includes the steps of collecting CRM information for a monitored address in a monitored cache; and recording the CRM information for the monitored address, when at least one of (1) the monitored address is cached in the monitored cache, (2) the monitored address is replaced in the monitored cache, (3) any cache line in a cache line set corresponding to the monitored address is cached in the monitored cache, and (4) any cache line in a cache line set corresponding to the monitored address is replaced in the monitored cache.
FILED Wednesday, May 18, 2005
APPL NO 11/131972
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/156
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US D581185 Annicelli
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Lance L. Annicelli (Bolling AFB, District of Columbia)
ABSTRACT
FILED Tuesday, August 14, 2007
APPL NO 29/291261
ART UNIT 2913 — Design
CURRENT CPC
Furnishings
D6/457
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07455837 Guo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Renfeng Guo (Ann Arbor, Michigan);  Niels C. Riedemann (Hannover, Germany);  Peter A. Ward (Ann Arbor, Michigan);  Markus Huber-Lang (Blaustein-Arnegg, Germany);  J. Vidya Sarma (Ann Arbor, Michigan)
ABSTRACT The present invention relates to methods and compositions for the diagnosis and treatment of sepsis. The present invention also provides methods of providing a prognosis to a patient with sepsis. In particular, the present invention relates to compositions and methods for the detection of C5aR expression and the correlation of C5aR expression level with prognosis in sepsis.
FILED Wednesday, November 05, 2003
APPL NO 10/701871
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/143.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455842 Yamshchikov
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Vladimir F. Yamshchikov (Olathe, Kansas)
ABSTRACT A chimeric West Nile live virus comprised of the NY99 and WN1415 strains and an infectious DNA recombinant construct encoding for the chimeric virus are provided, as well as immunogenic compositions and their method of use.
FILED Monday, December 05, 2005
APPL NO 11/294178
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/199.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455843 Connell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Research Foundation of State University of New York, The (Amherst, New York)
INVENTOR(S) Terry D. Connell (Williamsville, New York);  Michael W. Russell (East Amherst, New York);  Hesham Nawar (Buffalo, New York);  Sergio Arce (Williamsville, New York)
ABSTRACT The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens.
FILED Monday, September 27, 2004
APPL NO 10/950822
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/236.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455965 Barany et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Francis Barany (New York, New York);  Monib Zirvi (Willingboro, New Jersey);  Norman P. Gerry (Boston, Massachusetts);  Reyna Favis (Iselin, New Jersey);  Richard Kliman (Iselin, New Jersey)
ABSTRACT The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The first step of the method involves providing a first set of a plurality of tetramers of four nucleotides linked together, where (1) each tetramer within the first set differs from all other tetramers in the first set by at least two nucleotide bases, (2) no two tetramers within the first set are complementary to one another, (3) no tetramers within the first set are palindromic or dinucleotide repeats, and (4) no tetramer within the first set has one or less or three or more G or C nucleotides. Groups of 2 to 4 of the tetramers from the first set are linked together to form a collection of multimer units. From the collection of multimer units, all multimer units formed from the same tetramer and all multimer units having a melting temperature in ° C. of less than 4 times the number of tetramers forming a multimer unit are removed to form a modified collection of multimer units. The modified collection of multimer units is arranged in a list in order of melting temperature. The order of the modified collection of multimer units is randomized in 2° C. increments of melting temperature.
FILED Wednesday, April 04, 2001
APPL NO 10/257158
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455978 Thomas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University In The City of New York (New York, New York);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Philip Jordan Thomas (Dallas, Texas);  John F. Hunt (New York, New York);  William Christian Wigley (Dallas, Texas);  Rhesa D. Stidham (Dallas, Texas)
ABSTRACT Many proteins, when produced recombinantly, suffer from improper processing, folding and lack normal solubility. Modified proteins, including those indicative of disease states, also can have such defects. The present invention is directed to methods of identifying proper and improper protein folding, aberrant processing and/or insolubility. The method relies on the use of two components: a specialized fusion protein and structural complementation. The fusion protein contains sequences from the protein of interest and one portion of a marker protein that, by itself, is not active. A host cell then provides the remainder of the marker protein that serves to “complement” the function of the fused marker protein such that their association restores activity, permitting detection.
FILED Tuesday, December 30, 2003
APPL NO 10/748720
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455982 Barak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Molecular Devices Corporation (Sunnyvale, California)
INVENTOR(S) Larry S. Barak (Durham, North Carolina);  Robert H. Oakley (Durham, North Carolina)
ABSTRACT Methods of detecting G protein-coupled receptor (GPCR) activity in vitro and in vivo are provided. In one embodiment, the method includes providing at least one cell that expresses a GPCR and a plurality of conjugated proteins. Each of the plurality of conjugated proteins is formed by conjugating an arrestin protein and a detectable molecule. The plurality of conjugated proteins are substantially evenly distributed in the cytoplasm of the at least one cell. A first image of the at least one cell is obtained by detecting an amount of energy emitted from the detectable molecules and storing a value relative to the amount of energy. The at least one cell is treated with an agonist. A second image of the at least one cell is obtained. The first image and the second image are compared to detect the localization of at least some of the plurality of conjugated proteins at endocytic vesicles and/or endosomes.
FILED Monday, March 21, 2005
APPL NO 11/084928
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455986 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Dongfang Liu (Yorktown Heights, New York);  Kevin Pojasek (Cambridge, Massachusetts);  Zachary Shriver (Boston, Massachusetts);  Kristine Holley (Boston, Massachusetts);  Yosuf El-Shabrawi (Graz, Austria);  Ganesh Venkataraman (Bedford, Massachusetts);  Ram Sasisekharan (Bedford, Massachusetts)
ABSTRACT The invention relates to heparinase III and mutants thereof. Modified forms of heparinase III having reduced enzymatic activity which are useful for a variety of purposes, including sequencing of heparin-like glycosaminoglycans (HLGAGs), removing active heparan sulfate from a solution, inhibition of angiogenesis , etc. have been discovered according to the invention. The invention in other aspects relates to methods of treating cancer and inhibiting tumor cell growth and/or metastasis using heparinase III, or products produced by enzymatic cleavage by heparinase III of HLGAGs.
FILED Friday, July 22, 2005
APPL NO 11/187571
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455995 Tanner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S) Stephan Markus Tanner (Columbus, Ohio);  Albert de la Chapelle (Delaware, Ohio)
ABSTRACT Overexpression of the gene, BAALC, in biological samples from a patient is prognostic for tumor aggressiveness and unfavorable patient outcome. The present invention provides polynucleotide primers and probes for assaying for overexpression of BAALC transcripts. Kits containing the primers and probes are also provided. Also provided are antibodies for assaying for overexpression of BAALC proteins as well as peptide immunogens for producing the anti-BAALC antibodies. The present invention also provides methods for characterizing acute myelogenous leukemia, chronic myelogenous leukemia and prostate cancer in a patient, base on detection of BAALC overexpression.
FILED Tuesday, November 12, 2002
APPL NO 10/293239
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456011 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Osel, Inc. (Santa Clara, California)
INVENTOR(S) Xiaowen Liu (Cupertino, California);  Kirsten Essenmacher (Palo Alto, California);  David A. Simpson (Redwood City, California);  Qiang Xu (Cupertino, California)
ABSTRACT This disclosure relates to a modified version of cyanovirin-N protein and a transformed Lactobacillus bacterium that is capable of recombinantly expressing this modified protein. Further disclosed are polynucleotide sequence encoding the modified cyanovirin-N protein, expression cassette that allows the expression of the modified protein, and method of make and use of the modified protein as well as the transformed Lactobacillus bacterium. In addition, this disclosure describes two novel promoters originated from L. jensenii, which are capable of directing a high level of gene expression in Lactobacillus bacteria. Also described are an expression cassette comprising one of the novel promoters, a genetically modified Lactobacillus bacterium containing the expression cassette, a method for recombinant gene expression in Lactobacillus bacteria using the novel promoters, and a method for delivery of proteins with desired biological activity to a mucosal surface in a human.
FILED Thursday, January 12, 2006
APPL NO 11/331965
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456015 Bohn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Children's Memorial Hospital (Chicago, Illinois)
INVENTOR(S) Martha C. Bohn (Chicago, Illinois);  Lixin Jiang (Guangdong, China PRC);  Neva C. West (Chicago, Illinois);  Elio F. Vanin (Chicago, Illinois)
ABSTRACT A vector and a method are provided for delivering a nucleic acid to a nervous system cell. The vector includes a first nucleic acid, a second nucleic acid, inverted terminal repeats of adeno-associated virus, and a tetracycline-off regulatable promoter system that includes a first promoter operably linked to the first nucleic acid and a second promoter operably linked to the second nucleic acid. The promoters drive expression in opposite directions and away from the inverted terminal repeats. The method includes providing a recombinant adeno-associated viral (rAAV) vector and administering the vector to a nervous system cell. Expression of a product from the first nucleic acid is regulatable by the promoter system.
FILED Wednesday, November 15, 2006
APPL NO 11/600009
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456027 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Banyan Biomarkers, Inc. (Alachua, Florida)
INVENTOR(S) Kevin Ka-Wang Wang (Gainesville, Florida);  Ronald Hayes (Gainesville, Florida);  Ming Chen Liu (Gainesville, Florida);  Monika Oli (Gainesville, Florida)
ABSTRACT The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.
FILED Friday, April 15, 2005
APPL NO 11/106932
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Analytical and immunological testing
436/503
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456151 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Dean Y. Li (Salt Lake City, Utah);  Kye Won Park (Salt Lake City, Utah)
ABSTRACT The present invention provides methods and compositions for modulating proliferation, differentiation, migration, and adhesion of cardiovascular cell types.
FILED Thursday, July 14, 2005
APPL NO 11/183136
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456219 Miller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Merck HDAC Research, LLC (Boston, Massachusetts)
INVENTOR(S) Thomas A. Miller (New York, New York);  Victoria M. Richon (New York, New York);  Judy H. Chiao (Berkeley Heights, New Jersey)
ABSTRACT The present invention provides methods of selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inhibitors. The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high. Moreover, the pharmaceutical compositions unexpectedly give rise to high, therapeutically effective blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo. The present invention also provides a novel Form I polymorph of SAHA, characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry profile, as well a unique crystalline structure.
FILED Thursday, June 19, 2003
APPL NO 10/600132
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/575
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456222 Protopopova et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) Sequella, Inc. (Rockville, Maryland);  The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Marina Nikolaevna Protopopova (Silver Springs, Maryland);  Richard Edward Lee (Cordova, Tennessee);  Richard Allan Slayden (Ft. Collins, Colorado);  Clifton E. Barry, III (Germantown, Maryland);  Elena Bogatcheva (Bethesda, Maryland);  Leo Einck (McLean, Virginia)
ABSTRACT Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.
FILED Friday, July 01, 2005
APPL NO 11/173192
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/648
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456252 Strominger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jack L. Strominger (Lexington, Massachusetts);  Masha Fridkis-Hareli (Sudbury, Massachusetts)
ABSTRACT The invention provides peptide compositions and methods of making and using therapeutic compositions comprising peptides for the treatment of a subject having a demyelinating condition.
FILED Friday, June 10, 2005
APPL NO 11/150755
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456260 Rybak et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  The University of Reading (Berkshire, United Kingdom)
INVENTOR(S) Susanna M. Rybak (Green Cove Springs, Florida);  Juergen Krauss (Essen, Germany);  Michaela Arndt (Essen, Germany);  Andrew C. R. Martin (Ashtead, United Kingdom)
ABSTRACT The current invention provides new human variable chain framework regions and humanized antibodies comprising the framework regions. The invention also provides a new method of identifying framework acceptor regions in framework sequences for backmutation to graft a donor sequence to the human framework.
FILED Tuesday, June 17, 2003
APPL NO 10/515149
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456263 Sherman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Altor BioScience Corporation (, None)
INVENTOR(S) Linda A. Sherman (LaJolla, California);  Kimberlyn F. Card (Pembroke Pines, Florida);  Jon A. Weidanz (Amarillo, Texas);  Hing C. Wong (Weston, Florida);  Elizabeth L. Thomson (Miami, Florida)
ABSTRACT The invention provides T-cell receptor (TCR) molecules comprising a Vα chain and a Vβ chain that bind peptides derived from the p53 protein, preferably, the human p53 protein. The TCR molecules include both heterodimeric molecules and single chain molecules which specifically bind a sequence preferably spanning about amino acid positions 264-272 of the p53 protein displayed in the context of an HLA molecule, preferably, HLA-A2.1. Also disclosed are methods for making and using such TCR molecules. The invention has a wide spectrum of useful application including therapeutic uses and use in the detection of cells expressing p53 protein.
FILED Wednesday, June 05, 2002
APPL NO 10/163084
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.220
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456268 Bulavin et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dmitry Bulavin (Singapore, Singapore);  Ettore Appella (Chevy Chase, Maryland);  Albert J. Fornace, Jr. (Bethesda, Maryland);  Anne Kallioniemi (Tampere, Finland)
ABSTRACT Isolated or purified oligonucleotides and isolated or purified morpholino oligomers; a method of detecting cancer or a predisposition to cancer in a mammal, comprising comparing the level of expression of Wip1 in the mammal to a control; a method of treating cancer in a mammal that expresses the same or a higher level of Wip1 as compared to a mammal of the same species that does not have cancer, comprising administering to the mammal a cancer-treating effective amount of a Wip1 inhibitor; a method of screening an oligonucleotide or morpholino oligomer for the ability to inhibit the expression of Wip1; a method of determining the efficacy with which a test oligonucleotide or morpholino oligomer inhibits Wip1 expression; a method of screening a compound for Wip1-inhibiting activity; and a method of determining the efficacy with which a test compound inhibits Wip1.
FILED Monday, October 08, 2007
APPL NO 11/868794
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/22.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456271 Frey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Perry A. Frey (Madison, Wisconsin);  Frank J. Ruzicka (Lodi, Wisconsin)
ABSTRACT There are provided nucleic acids, including isolated DNA molecules, which encode glutamate 2,3-aminomutase enzymes, polypeptides produced from such nucleic acids and methods of making the nucleic acids and polypeptides. There are further provided methods of producing β-glutamate from glutamate using glutamate 2,3-aminomutase.
FILED Wednesday, October 11, 2006
APPL NO 11/546029
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456768 La Rue et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S)
ASSIGNEE(S) Washington State University (Pullman, Washington)
INVENTOR(S) George S. La Rue (Pullman, Washington);  Haidong Guo (Mountain View, California)
ABSTRACT An analog-to-digital converter based on an interleaving architecture is disclosed. The analog-to-digital converter can include a first sample and hold circuit for sampling and temporarily storing a first input signal. The analog-to-digital converter can also include a comparator for converting the sampled first input signal into a digital signal in a first time period. The analog-to-digital converter can further include a second sample and hold circuit for sampling and temporarily storing a second input signal in a second time period. The second time period at least partially overlaps with the first time period.
FILED Friday, April 06, 2007
APPL NO 11/697509
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/141
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US 07457655 Welch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation For Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Edward Brian Welch (Rochester, Minnesota);  Armando Manduca (Rochester, Minnesota)
ABSTRACT Magnetic resonance images reconstructed from a radial/projection acquisition are corrected for motion corruption caused by in-plane translational and in-plane rotational motion of an imaged subject using only the projection data itself. The method is based on the consistency properties of the 0th, 1st, and 2nd order moments of the spatial domain projections. In-plane translational motion is corrected by shifting/aligning the spatial projections according to the center of mass of each projection, which is calculated using the 0th and 1st moments. In-plane rotational motion is accounted for by determining the rotational motion time record using the 2nd moment information. The determination of the rotational motion time record using the 2nd moments is made possible by acquiring the successive MR projections at a view angle spacing that is substantially 45° and thus achieves sufficient linear independence. The translation-corrected spatial projections are reconstructed using the actual projection view angles, which are sum of the intended projection view angles plus the detected in-plane rotational motion time record. The calculation may also be performed in real-time during data acquisition in order to reacquire projections found to be too inconsistent due to through plane motion or other changes that are not in-plane rigid body motions or to acquire projections determined to be missing from the data set due to rotational motion.
FILED Friday, October 08, 2004
APPL NO 10/962105
ART UNIT 3768 — Semiconductors/Memory
CURRENT CPC
Surgery
6/407
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07455854 Gower et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Laurie B. Gower (Gainesville, Florida);  Matthew J. Olszta (Gainesville, Florida)
ABSTRACT The present invention pertains to mineral fibers useful as biomimetics of tissue, such as dental enamel and bone, and as filler in paper, paint, coatings, and plastic production. The present invention also concerns methods for producing mineral fibers by contacting an inorganic liquid-phase mineral precursor with a crystalline inorganic substrate under conditions permitting the inorganic liquid-phase mineral precursor to solidify and crystallize, compositions comprising mineral fibers, and methods for treating a tissue defect within a patient by applying mineral fibers to the site of the tissue defect.
FILED Monday, April 05, 2004
APPL NO 10/819040
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/423
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455927 DiSalvo, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Francis J. DiSalvo, Jr. (Ithaca, New York);  Hector D. Abruna (Ithaca, New York)
ABSTRACT The invention is directed to intermetallic compounds for use as catalysts for chemical reactions and catalytic systems. The structure of ordered intermetallic compounds enables such compounds to function as highly efficient catalysts. The ordered intermetallic compounds may be used to catalyze reactions in fuel cells (e.g., hydrogen fuel cells), amongst numerous other applications.
FILED Tuesday, July 29, 2003
APPL NO 10/630237
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456013 Mach et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Chromatin, Inc. (Chicago, Illinois);  University of Chicago (Chicago, Illinois)
INVENTOR(S) Jennifer Mach (Chicago, Illinois);  Helge Zieler (Chicago, Illinois);  RongGuan Jin (Chicago, Illinois);  Kevin Keith (Chicago, Illinois);  Gregory Copenhaver (Chapel Hill, North Carolina);  Daphne Preuss (Chicago, Illinois)
ABSTRACT The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
FILED Friday, January 07, 2005
APPL NO 11/031554
ART UNIT 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456273 Mauro et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Vincent P. Mauro (San Diego, California);  Gerald M. Edelman (La Jolla, California);  Stephen A. Chappell (Del Mar, California);  Frederick S. Jones (Cardiff, California);  Geoffrey Owens (San Diego, California);  Robyn Meech (San Diego, California)
ABSTRACT Provided are methods of identifying oligonucleotides having transcriptional or translational activity by integrating ilie oligonucleotide into a eukaryotic cell genome such that the oligonucleotide is operatively linked to an expressible polynucleotide, and detecting a change in expression of the expressible polynucleotide due to the operatively linked oligonucleotide. Also provided are vectors useful for identifying an oligonucleotide having transcriptional or translational regulatory activity according to a method of the invention. In addition, isolated synthetic transcriptional or translational regulatory elements identified according to a method of the invention are provided, as are kits, which contain a vector useful for identifying a transcriptional or translational regulatory element, or an isolated synthetic transcriptional or translational regulatory element or plurality of such elements. Also provided are isolated transcriptional regulatory elements.
FILED Wednesday, November 29, 2006
APPL NO 11/607131
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456491 Pilla
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Subrahmanyam V. S. Pilla (San Diego, California)
ABSTRACT The present invention relates to a various systems for generating and directing electron flow, and related methods, manufacturing techniques and related componentry, such as can be used in lithography, microscopy and other applications. In one embodiment, the present invention involves a system that includes an electron source having a plurality of independently-actuatable emission surfaces each of which is capable of emitting electrons, and an optical column adjacent to the electron source through which the emitted electrons pass. The optical column includes a plurality of actuatable electrodes that are capable of influencing paths taken by the emitted electrons.
FILED Friday, July 22, 2005
APPL NO 11/188043
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/653
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US 07456595 Ratliff et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents for Oklahoma State University (Stillwater, Oklahoma)
INVENTOR(S) Ryan Todd Ratliff (O'Fallon, Missouri);  Prabhakar R. Pagilla (Stillwater, Oklahoma)
ABSTRACT According to a preferred aspect of the instant invention, there is provided a system and method of moving a disc drive arm in the presence of nonlinear magnetic bias. Further, in another preferred embodiment the instant method will be adaptive and/or self-corrective and is especially useful when used with disc drive hardware other than the hardware that was used to model the control law.
FILED Tuesday, April 18, 2006
APPL NO 11/406177
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Motive power systems
318/560
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456698 Gianchandani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Yogesh B. Gianchandani (Ann Arbor, Michigan);  Kabir Udeshi (Ann Arbor, Michigan)
ABSTRACT A mechanical self-reciprocating oscillator and mechanism and method for establishing and maintaining regular back and forth movement of a micromachined device without the aid of any electronic components are provided. The fully mechanical micromachined oscillator and mechanism are driven using only a DC power source on at least one substrate such as a semiconductor chip. The oscillator and mechanism preferably include an electrothermal actuator, that, when actuated, opens a switch to cut off supply current to the actuator. Two versions of the oscillator and mechanism are provided using distinct hysteresis mechanisms, one structural and the other thermal.
FILED Thursday, January 20, 2005
APPL NO 11/038873
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/154
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456972 Ke et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) Pu-Chun Ke (Clemson, South Carolina);  Francesco Stellacci (Somerville, Massachusetts);  Apparao M. Rao (Anderson, South Carolina)
ABSTRACT Disclosed are optical devices including one or more carbon nanotubes that can function as plasmon waveguides. The presently disclosed devices advantageously utilize the existence of surface plasmons on carbon nanotubes through the generation and transport of surface plasmon polaritons across the nanotubes. Also disclosed are methods for tuning the devices through particular formation parameters for the nanotubes and/or selection of particular substrate materials. Systems of the present invention can provide optical data concerning a sample, for instance via construction of an NSOM image, as well as topological date concerning a sample via construction of an AFM image. In one embodiment, the disclosed systems can provide simultaneous acquisition of optical images and topological images.
FILED Friday, January 13, 2006
APPL NO 11/332840
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457338 Mawst et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Luke J. Mawst (Sun Prairie, Wisconsin);  Nelson Tansu (Bethlehem, Pennsylvania);  Jeng-Ya Yeh (Portland, Oregon)
ABSTRACT In accordance with the present invention, GaAs-based optoelectronic devices have an active region that includes a well layer composed of a compressively-strained semiconductor that is free, or substantially free, of nitrogen disposed between two barrier layers composed of a nitrogen- and indium-containing semiconductor.
FILED Wednesday, April 19, 2006
APPL NO 11/406834
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/43.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457340 Botez
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Dan Botez (Madison, Wisconsin)
ABSTRACT A semiconductor laser is formed on a semiconductor substrate with an array of laterally spaced laser device elements each including a second order distributed feedback grating bounded by distributed Bragg reflector gratings. The device elements in which the distributed feedback grating and the distributed Bragg reflector gratings are formed have a lower effective index than the index of the interelement regions and are spaced so as to form an antiguided array.
FILED Friday, April 22, 2005
APPL NO 11/112749
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/50.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457367 Farhang-Boroujeny et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Behrouz Farhang-Boroujeny (Salt Lake City, Utah);  Haidong Zhu (Salt Lake City, Utah);  Zhenning Shi (Braddon, Australia);  Stephen Andrew Laraway (Layton, Utah)
ABSTRACT A detector and method for estimating channel data probability in a multi-user or multiple-input multiple-output communication system includes summing conditional bit probabilities conditioned on hypothetical channel data patterns over stochastically selected hypothetical channel data patterns. Various detailed hardware structures and circuits are also described.
FILED Thursday, July 07, 2005
APPL NO 11/177938
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/262
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07455046 Biruduganti et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) U Chicago Argonne LLC (Chicago, Illinois)
INVENTOR(S) Munidhar S. Biruduganti (Naperville, Illinois);  Sreenath Borra Gupta (Naperville, Illinois);  R. Raj Sekar (Naperville, Illinois);  Steven S. McConnell (Shorewood, Illinois)
ABSTRACT A method and system for reducing nitrous oxide emissions from an internal combustion engine. An input gas stream of natural gas includes a nitrogen gas enrichment which reduces nitrous oxide emissions. In addition ignition timing for gas combustion is advanced to improve FCE while maintaining lower nitrous oxide emissions.
FILED Friday, June 09, 2006
APPL NO 11/450619
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Internal-combustion engines
123/406.450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455471 Gawehn
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S)
ASSIGNEE(S) Eric M. Gawehn (Mountain View, California)
INVENTOR(S) Eric Gawehn (Mountain View, California)
ABSTRACT Fastening systems for parts that endure high vibration shear loads have traditionally been difficult or expensive to produce. This application describes a fastening system with multiple conical surfaces and eccentric offsets. The novel conical fastener system allows parts to be assembled with reduced tolerance controls at interface features while improving alignment precision. The eccentric conical fastening system is particularly well suited for assemblies with high shear loads in high vibration/shock environments, and/or for systems that have extremely precise pointing requirements.
FILED Tuesday, May 17, 2005
APPL NO 11/132054
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Joints and connections
43/374.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456013 Mach et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Chromatin, Inc. (Chicago, Illinois);  University of Chicago (Chicago, Illinois)
INVENTOR(S) Jennifer Mach (Chicago, Illinois);  Helge Zieler (Chicago, Illinois);  RongGuan Jin (Chicago, Illinois);  Kevin Keith (Chicago, Illinois);  Gregory Copenhaver (Chapel Hill, North Carolina);  Daphne Preuss (Chicago, Illinois)
ABSTRACT The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
FILED Friday, January 07, 2005
APPL NO 11/031554
ART UNIT 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456131 Klett et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) James Klett (Knoxville, Tennessee);  Lynn Klett (Knoxville, Tennessee);  Jonathan Kaufman (Leonardtown, Maryland)
ABSTRACT A monolith comprises a zeolite, a thermally conductive carbon, and a binder. The zeolite is included in the form of beads, pellets, powders and mixtures thereof. The thermally conductive carbon can be carbon nano-fibers, diamond or graphite which provide thermal conductivities in excess of about 100 W/m·K to more than 1,000 W/m·K. A method of preparing a zeolite monolith includes the steps of mixing a zeolite dispersion in an aqueous colloidal silica binder with a dispersion of carbon nano-fibers in water followed by dehydration and curing of the binder is given.
FILED Monday, August 28, 2006
APPL NO 11/510924
ART UNIT 4162 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/417
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456314 Han, legal representative
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) E.I. du Pont de Nemours and Company (Wilmington, Delaware)
INVENTOR(S) Amy Qi Han, legal representative (Hockessin, Delaware)
ABSTRACT Partially fluorinated ionic compounds are prepared. They are useful in the preparation of partially fluorinated dienes, in which the repeat units are cycloaliphatic.
FILED Thursday, December 13, 2007
APPL NO 11/955508
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
564/35
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456630 Gerald, II et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) U Chicago Argonne LLC (Chicago, Illinois)
INVENTOR(S) Rex E. Gerald, II (Brookfield, Illinois);  Robert J. Klingler (Glenview, Illinois);  Jerome W. Rathke (Homer Glen, Illinois);  Rocio Diaz (Chicago, Illinois);  Lela Vukovic (Westchester, Illinois)
ABSTRACT A method, apparatus, and system for characterizing thin film materials. The method, apparatus, and system includes a container for receiving a starting material, applying a gravitational force, a magnetic force, and an electric force or combinations thereof to at least the starting material, forming a thin film material, sensing an NMR signal from the thin film material and analyzing the NMR signal to characterize the thin film of material.
FILED Tuesday, July 11, 2006
APPL NO 11/484348
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/307
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456954 Weiss et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Shimon Weiss (Los Angeles, California);  Achillefs Kapanidis (Oakland, California);  Ted A. Laurence (Livermore, California);  Nam K. Lee (Seoul, South Korea)
ABSTRACT Fluorescence, spectroscopy is used to analyze small numbers of molecules that are present in a relatively small detection volume or zone. Information regarding physical and chemical properties of these molecules is determined by rapidly modulating the wavelength, intensity and/or polarization of laser energy to excite fluorophores that are attached either to the molecule of interest or a molecule that interacts with the molecule of interest. The emission profile of the fluorophores is used to determine useful information about the labeled and/or non-labeled molecules including molecular interactions between the molecules.
FILED Thursday, June 17, 2004
APPL NO 10/561448
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/318
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457187 Bright et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Arthur A. Bright (Croton-on-Hudson, New York);  Paul G. Crumley (Yorktown Heights, New York);  Marc Dombrowa (Bronx, New York);  Steven M. Douskey (Rochester, Minnesota);  Rudolf A. Haring (Cortlandt Manor, New York);  Steven F. Oakland (Colchester, Vermont);  Michael R. Quellette (Westford, Vermont);  Scott A. Strissel (Byron, Minnesota)
ABSTRACT A design structure for repairing an integrated circuit during operation of the integrated circuit. The integrated circuit comprising of a multitude of memory arrays and a fuse box holding control data for controlling redundancy logic of the arrays. The design structure provides the integrated circuit with a control data selector for passing the control data from the fuse box to the memory arrays; providing a source of alternate control data, external of the integrated circuit; and connecting the source of alternate control data to the control data selector. The design structure further passes the alternate control data from the source thereof, through the control data selector and to the memory arrays to control the redundancy logic of the memory arrays.
FILED Friday, September 07, 2007
APPL NO 11/851613
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/225.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457328 Holtom
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Gary R. Holtom (Richland, Washington)
ABSTRACT A mode-locked laser employs a coupled-polarization scheme for efficient longitudinal pumping by reshaped laser diode bars. One or more dielectric polarizers are configured to reflect a pumping wavelength having a first polarization and to reflect a lasing wavelength having a second polarization. A Yb-doped gain medium can be used that absorbs light having a first polarization and emits light having a second polarization. Using such pumping with laser cavity dispersion control, pulse durations of less than 100 fs can be achieved.
FILED Wednesday, May 17, 2006
APPL NO 11/436731
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/18
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07457785 Greitzer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Frank L. Greitzer (Richland, Washington);  Lars J. Kangas (West Richland, Washington);  Kristine M. Terrones (Los Alamos, New Mexico);  Melody A. Maynard (Richland, Washington);  Ronald A. Pawlowski (West Richland, Washington);  Thomas A. Ferryman (Richland, Washington);  James R. Skorpik (Kennewick, Washington);  Bary W. Wilson (Coconut Creek, Florida)
ABSTRACT A method and computer-based apparatus for monitoring the degradation of, predicting the remaining service life of, and/or planning maintenance for, an operating system are disclosed. Diagnostic information on degradation of the operating system is obtained through measurement of one or more performance characteristics by one or more sensors onboard and/or proximate the operating system. Though not required, it is preferred that the sensor data are validated to improve the accuracy and reliability of the service life predictions. The condition or degree of degradation of the operating system is presented to a user by way of one or more calculated, numeric degradation figures of merit that are trended against one or more independent variables using one or more mathematical techniques. Furthermore, more than one trendline and uncertainty interval may be generated for a given degradation figure of merit/independent variable data set. The trendline(s) and uncertainty interval(s) are subsequently compared to one or more degradation figure of merit thresholds to predict the remaining service life of the operating system. The present invention enables multiple mathematical approaches in determining which trendline(s) to use to provide the best estimate of the remaining service life.
FILED Friday, August 25, 2000
APPL NO 10/362717
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/12
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07455264 Wakayama
FUNDED BY
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) McDonnell Douglas Corporation (St. Louis, Missouri)
INVENTOR(S) Sean R. Wakayama (Huntington Beach, California)
ABSTRACT Independently deflectable control surfaces are located on the trailing edge of the wing of a blended wing-body aircraft. The reconfiguration control system of the present invention controls the deflection of each control surface to optimize the spanwise lift distribution across the wing for each of several flight conditions, e.g., cruise, pitch maneuver, and high lift at low speed. The control surfaces are deflected and reconfigured to their predetermined optimal positions when the aircraft is in each of the aforementioned flight conditions. With respect to cruise, the reconfiguration control system will maximize the lift to drag ratio and keep the aircraft trimmed at a stable angle of attack. In a pitch maneuver, the control surfaces are deflected to pitch the aircraft and increase lift. Moreover, this increased lift has its spanwise center of pressure shifted inboard relative to its location for cruise. This inboard shifting reduces the increased bending moment about the aircraft's x-axis occasioned by the increased pitch force acting normal to the wing. To optimize high lift at low speed, during take-off and landing for example, the control surfaces are reconfigured to increase the local maximum coefficient of lift at stall-critical spanwise locations while providing pitch trim with control surfaces that are not stall critical.
FILED Tuesday, August 26, 1997
APPL NO 08/917480
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/215
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456019 Goodwin et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Regenetech, Inc. (Sugar Land, Texas);  The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Thomas J. Goodwin (Kemah, Texas);  Clayton R. Parker (Safety Harbor, Florida)
ABSTRACT An improved three-dimensional cell to tissue development process using a specific time varying electromagnetic force, pulsed, square wave, with minimum fluid shear stress, freedom for 3-dimensional spatial orientation of the suspended particles and localization of particles with differing or similar sedimentation properties in a similar spatial region.
FILED Wednesday, June 29, 2005
APPL NO 11/169385
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/394
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456537 Kascak et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Peter E. Kascak (Eaton Township, Ohio);  Ralph H. Jansen (Eaton Township, Ohio);  Timothy P. Dever (Westlake, Ohio)
ABSTRACT A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.
FILED Thursday, December 15, 2005
APPL NO 11/304359
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/90.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456942 Curley et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Michael J. Curley (Huntsville, Alabama);  Sergey S. Sarkisov (Huntsville, Alabama)
ABSTRACT A refractometer computer controls the rotation of a rotary plate upon which are mounted a prism optically coupled via an optical window to a spectroscopic cell holding a resin exhibiting a dynamic refractive index during photocuring. The computer system positions the prism and spectroscopic cell relative to a visible light laser which illuminates the prism-resin interface at selected incidence angles. A photodetector mounted on the plate generates a signal to the computer proportional to intensity of an internally reflected light beam. A curing light is selectively transmitted through the prism and into the photocurable resin. The refractometer determines the intensity of the internally reflected beam a selected incidence angles and determines the effective refractive index curve of the resin at an uncured state and, optionally, at a completely cured state. Next, an amount of uncured resin and selected optical components to be joined by the resin is placed in the spectroscopic cell and irradiated with the UV light. The refractometer is fixed at a selected incidence angle and measures the intensity of an internally reflected light beam of light throughout the cure cycle. The refractometer determines the resin's refractive index of the polymeric mixture by means of extrapolation of a horizontal shift in the effective refractive index curve of the resin from an uncured state to a selected point in the cure cycle.
FILED Tuesday, October 17, 2006
APPL NO 11/582625
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/136
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07455955 Shih et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S)
ASSIGNEE(S) Brewer Science Inc. (Rolla, Missouri)
INVENTOR(S) Wu-Sheng Shih (Rolla, Missouri);  James E. Lamb, III (Rolla, Missouri);  Juliet Ann Minzey Snook (Cook Station, Missouri);  Mark G. Daffron (Rolla, Missouri)
ABSTRACT The present invention is directed towards contact planarization methods that can be used to planarize substrate surfaces having a wide range of topographic feature densities for lithography applications. These processes use thermally curable, photo-curable, or thermoplastic materials to provide globally planarized surfaces over topographic substrate surfaces for lithography applications. Additional coating(s) with global planarity and uniform thickness can be obtained on the planarized surfaces. These inventive methods can be utilized with single-layer, bilayer, or multi-layer processing involving bottom anti-reflective coatings, photoresists, hardmasks, and other organic and inorganic polymers in an appropriate coating sequence as required by the particular application. More specifically, this invention produces globally planar surfaces for use in dual damascene and bilayer processes with greatly improved photolithography process latitude. The invention further provides globally planar surfaces to transfer patterns using imprint lithography, nano-imprint lithography, hot-embossing lithography and stamping pattern transfer techniques.
FILED Monday, February 24, 2003
APPL NO 10/373897
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/311
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07456424 Wu et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S) Yiliang Wu (Mississauga, Canada);  Beng S. Ong (Mississauga, Canada);  Yu Qi (Oakville, Canada);  Yuning Li (Mississauga, Canada)
ABSTRACT A thin film transistor composed of a semiconductor layer including an optionally substituted indolocarbazole.
FILED Monday, June 27, 2005
APPL NO 11/167485
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07456013 Mach et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Chromatin, Inc. (Chicago, Illinois);  University of Chicago (Chicago, Illinois)
INVENTOR(S) Jennifer Mach (Chicago, Illinois);  Helge Zieler (Chicago, Illinois);  RongGuan Jin (Chicago, Illinois);  Kevin Keith (Chicago, Illinois);  Gregory Copenhaver (Chapel Hill, North Carolina);  Daphne Preuss (Chicago, Illinois)
ABSTRACT The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
FILED Friday, January 07, 2005
APPL NO 11/031554
ART UNIT 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07455264 Wakayama
FUNDED BY
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) McDonnell Douglas Corporation (St. Louis, Missouri)
INVENTOR(S) Sean R. Wakayama (Huntington Beach, California)
ABSTRACT Independently deflectable control surfaces are located on the trailing edge of the wing of a blended wing-body aircraft. The reconfiguration control system of the present invention controls the deflection of each control surface to optimize the spanwise lift distribution across the wing for each of several flight conditions, e.g., cruise, pitch maneuver, and high lift at low speed. The control surfaces are deflected and reconfigured to their predetermined optimal positions when the aircraft is in each of the aforementioned flight conditions. With respect to cruise, the reconfiguration control system will maximize the lift to drag ratio and keep the aircraft trimmed at a stable angle of attack. In a pitch maneuver, the control surfaces are deflected to pitch the aircraft and increase lift. Moreover, this increased lift has its spanwise center of pressure shifted inboard relative to its location for cruise. This inboard shifting reduces the increased bending moment about the aircraft's x-axis occasioned by the increased pitch force acting normal to the wing. To optimize high lift at low speed, during take-off and landing for example, the control surfaces are reconfigured to increase the local maximum coefficient of lift at stall-critical spanwise locations while providing pitch trim with control surfaces that are not stall critical.
FILED Tuesday, August 26, 1997
APPL NO 08/917480
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/215
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07456509 Gray, Jr.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia)
INVENTOR(S) Charles L. Gray, Jr. (Pinckney, Michigan)
ABSTRACT The invention is directed toward methods for operating a series hybrid vehicle in a manner that responds to the operator's demand for power output, while maximizing engine efficiency and minimizing disruptions in vehicle drivability. According to principles of the present invention, when the driver of a series hybrid vehicle makes a demand for power output, whether the secondary power source(s) is supplied with secondary energy stored in an energy storage device(s), direct input energy generated by an engine(s), or both, depends on the amount of available secondary energy stored in the vehicle's secondary storage device(s) alone, and in combination with vehicle speed. During the time that the engine is used to generate secondary energy, the power efficiency level at which the engine is operated also depends on the vehicle speed and the amount of available secondary energy stored in the vehicle's secondary storage device alone, and in combination with vehicle speed. Further, in some embodiments, when the engine is not generating secondary energy, the engine is selectively turned off or idled in response to various operating conditions.
FILED Monday, February 14, 2005
APPL NO 11/058378
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Prime-mover dynamo plants
290/40.C00
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07457756 Nelson et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Director of the National Security Agency (Washington, District of Columbia)
INVENTOR(S) Douglas J. Nelson (Columbia, Maryland);  David Charles Smith (Columbia, Maryland)
ABSTRACT A method of generating a time-frequency representation of a signal that preserves phase information by receiving the signal, calculating a joint time-frequency domain of the signal, estimating instantaneous frequencies of the joint time-frequency domain, modifying each estimated instantaneous frequency, if necessary, to correspond to a frequency of the joint time-frequency domain to which it most closely compares, redistributing the elements within the joint time-frequency domain according to the estimated instantaneous frequencies as modified, computing a magnitude for each element in the joint time-frequency domain as redistributed, and plotting the results as the time-frequency representation of the signal.
FILED Thursday, June 09, 2005
APPL NO 11/149005
ART UNIT 2626 — Selective Visual Display Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/276
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07456013 Mach et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Chromatin, Inc. (Chicago, Illinois);  University of Chicago (Chicago, Illinois)
INVENTOR(S) Jennifer Mach (Chicago, Illinois);  Helge Zieler (Chicago, Illinois);  RongGuan Jin (Chicago, Illinois);  Kevin Keith (Chicago, Illinois);  Gregory Copenhaver (Chapel Hill, North Carolina);  Daphne Preuss (Chicago, Illinois)
ABSTRACT The present invention provides for the nucleic acid sequences of plant centromeres. This will permit construction of stably inherited recombinant DNA constructs and minichromosomes which can serve as vectors for the construction of transgenic plant and animal cells.
FILED Friday, January 07, 2005
APPL NO 11/031554
ART UNIT 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07455839 Vale et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Research Development Foundation (Carson City, Nevada)
INVENTOR(S) Wylie Vale (La Jolla, California);  Kathy A. Lewis (San Diego, California);  Peter C. Gray (Encinitas, California);  Louise M. Bilezikjian (San Diego, California);  Amy L. Blount (La Jolla, California)
ABSTRACT Inhibins and activins are protein hormones that reciprocally modulate a diversity of regulatory pathways. Competitive binding experiments revealed that betaglycan, the type III TGF-β receptor, also functions as an inhibin receptor. Betaglycan augments the binding of inhibin to the ActRII activin receptor. By augmenting inhibin binding to ActRII, betaglycan effectively sequesters ActRII away from activin and thereby reduces activin signaling. In addition, the ActRII-betaglycan complex may generate novel signals distinct from those initiated by activin signaling via ActRII and ALK4. Betaglycan is produced in discrete nuclei of the rat brain and by specific cell types within the adult rat pituitary, testis, and ovary. The presence of betaglycan within inhibin-responsive tissues and cell types, together with the ability of this protoglycan to bind inhibin and to confer inhibin sensitivity, is consistent with a role of betaglycan as an inhibin-specific receptor mediating inhibin responses within various tissues.
FILED Wednesday, October 29, 2003
APPL NO 10/696717
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/158.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455969 Rice, III et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Charles M. Rice, III (New York, New York);  Keril J. Blight (St. Louis, Missouri)
ABSTRACT This invention relates generally to cells and cell lines that are permissive for hepatitis C virus (HCV) replication, and methods and materials for making and using them. The subject cell line referred to as Huh-7.5 has the A.T.C.C. designation number PTA-8561, having been deposited on Aug. 1, 2007.
FILED Thursday, November 13, 2003
APPL NO 10/534571
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07455972 Virgin
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Herbert W. Virgin (Clayton, Missouri)
ABSTRACT The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto.
FILED Monday, March 06, 2006
APPL NO 11/368804
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 25, 2008.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2008/fedinvent-patents-20081125.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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