FedInvent™ Patents
Patent Details for Tuesday, May 12, 2009
This page was updated on Monday, March 27, 2023 at 01:24 AM GMT
Department of Health and Human Services (HHS)
07531073 — Sparsely cross-linked nanogels: a novel polymer structure for microchannel DNA sequencing
| US 07531073 | Barron et al. |
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| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Annelise Barron (Evanston, Illinois); Erin Doherty (Wilmington, Delaware) |
| ABSTRACT | The present invention is generally directed to novel polymeric materials for use in the electrophoretic separation of nucleic acids. In particular, the novel polymer materials are sparsely crosslinked nanogels, dissolved in an aqueous buffer to form solutions with moderate to high viscosity. The present invention further provides methods for generating such novel polymers, and related methods of their use. |
| FILED | Wednesday, June 11, 2008 |
| APPL NO | 12/137291 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/470 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531167 | Glorioso et al. |
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| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Joseph C. Glorioso (Blawnox, Pennsylvania); Darren Wolfe (Verona, Arizona); David Krisky (Sewickley, Pennsylvania) |
| ABSTRACT | The invention provides a herpes simplex virus vector comprising deletions in ICP4, ICP27, and UL55. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/694118 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531170 | Croft et al. |
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| ASSIGNEE(S) | La Jolla Institute for Allergy and Immunology (La Jolla, California) |
| INVENTOR(S) | Michael Croft (San Diego, California); Shahram Salek-Ardakani (San Diego, California) |
| ABSTRACT | T cell memory can persist in the absence of antigen. However, some memory cells by default are subject to signals accompanying periodic antigen exposure. OX40 is essential to the extent and persistence of Th2 memory when antigen is re-encountered. In an animal model of allergic asthma, inhibiting OX40/OX40L signaling during the secondary response to inhaled antigen suppressed lung inflammation. Inhibiting OX40 at the time of memory cell reactivation reduced the longevity of memory with further inflammation prevented upon tertiary encounter with antigen. |
| FILED | Thursday, September 07, 2006 |
| APPL NO | 11/518364 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531180 | Polo et al. |
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| ASSIGNEE(S) | Novartis Vaccines and Diagnostics, Inc (Emeryville, California) |
| INVENTOR(S) | John M. Polo (Hayward, California); Silvia Perri (Castro Valley, California); Kent Thudium (Oakland, California) |
| ABSTRACT | Chimeric alphaviruses and alphavirus replicon particles are provided including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed. |
| FILED | Thursday, April 11, 2002 |
| APPL NO | 10/123101 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531181 | Danishefsky et al. |
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| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Samuel J. Danishefsky (Englewood, New Jersey); Vadim Dudkin (New York, New York); Xudong Geng (New York, New York); Mihirbaran Mandal (New York, New York); Isaac Kraus (New York, New York) |
| ABSTRACT | The present invention provides multi-antigenic constructs comprising one or more carbohydrate antigens having the formula: wherein R1, R2A, R2B, R3, R4, W1, W2 and W3 are as defined herein; and additionally provides compositions thereof, and methods for their use in the treatment and/or prevention of HIV infection, and methods for inducing HIV-specific antibodies in a subject, comprising administering to a subject in need thereof, an effective amount of any of the inventive compounds as disclosed herein, either in conjugated form or unconjugated and in combination with a suitable immunogenic carrier. In another aspect, the invention provides an antibody or antibody fragment which binds specifically to a gp120 glycan or glycopeptide of the invention. |
| FILED | Friday, June 03, 2005 |
| APPL NO | 11/145084 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531183 | Singh et al. |
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| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Shashi Kant Sharma (New Bedford, Massachusetts) |
| ABSTRACT | An isolated, biologically active 33 kDa Hemagglutinin purified from the type A Clostridium botulinum neurotoxin complex and its uses are described. |
| FILED | Tuesday, November 22, 2005 |
| APPL NO | 11/286515 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531299 | DeLeon et al. |
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| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Patricia A. DeLeon (Bear, Delaware); Hong Chen (Shanghai, China PRC); Hong Zhang (Newark, Delaware); Genevieve S. Griffiths (Wilmington, Delaware) |
| ABSTRACT | The invention relates to the in vitro transfer of the Sperm Adhesion Molecule 1 (SPAM 1) to spermatozoa. The SPAM1 protein can be obtained from the epididmys or the uterus and should have an intact lipid anchor. The SPAM 1 protein attaches to the surface of mammalian spermatozoa via it's lipid anchor in an in vitro environment in order to increase the sperm's capability of fertilizing an egg. |
| FILED | Wednesday, December 08, 2004 |
| APPL NO | 11/007065 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531307 | Wigler et al. |
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| ASSIGNEE(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Michael Wigler (Cold Spring Harbor, New York); Robert Lucito (Mineola, New York) |
| ABSTRACT | It is an object of the present invention to provide a solution to problems associated with the use of microarray technology for the analysis DNA. The present invention provides compositions and methods for the use of simple and compound representations of DNA in microarray technology. The present invention is also directed to methods for the production of High Complexity Representations (HCRs) of the DNA from cells. |
| FILED | Wednesday, March 30, 2005 |
| APPL NO | 11/094388 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531309 | Davies et al. |
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| ASSIGNEE(S) | Michigan State University (Lansing, Michigan) |
| INVENTOR(S) | Dele Davies (Okemos, Michigan); David W. Lacher (Lansing, Michigan); Thomas S. Whittam (Okemos, Michigan); Shannon Manning (Howell, Michigan) |
| ABSTRACT | The present invention relates to molecular diagnostics. In particular, the present invention relates to PCR based diagnostics for the typing of Group B streptococci. |
| FILED | Tuesday, December 06, 2005 |
| APPL NO | 11/294830 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531317 | Fox et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian G. Fox (Madison, Wisconsin); Paul G. Blommel (Blue Mounds, Wisconsin) |
| ABSTRACT | The invention discloses a method of determining protease activity, in real time, using fluorescence polarization technology. In particular, the invention provides vectors and a method for their use, which expresses uncharacterized proteins conjugated to a fluorescence tag, which binds specifically to a fluorescent ligand. Cleavage of the recombinant protein results in a fragment of the expressed peptide and results in a change in fluorescence polarization of the fluorophore. The rate of change in fluorescence polarization can be measured in real time and is equivalent to the rate of protease cleavage. |
| FILED | Wednesday, November 24, 2004 |
| APPL NO | 10/997651 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531337 | Escalante-Semerena et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jorge C. Escalante-Semerena (Madison, Wisconsin); Vincent J. Starai (Madison, Wisconsin) |
| ABSTRACT | A method for modulating the activity of an AMP-forming enzyme (AFE) is disclosed. The method is based upon the novel observation that the activity of these enzymes is controlled by acetylation of the enzymes to inactivate them and de-acetylation of the enzymes to re-activate them. The acetylation of the enzyme occurs at a characteristic lysine residue. Various polypeptides, nucleic acids and other molecules that are related to modulating the AFE activity are also disclosed. Further disclosed are methods of modulating cellular acetyl-CoA or propionyl-CoA levels in bacterial hosts, methods of identifying agents that can modulate the activity of AFE acetylases, and methods of identifying AFE mutants that are insensitive to acetylation regulation. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/456097 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531338 | Liu et al. |
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| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jian Liu (Chapel Hill, North Carolina); Guoqing Xia (Hamburg, Germany); Jinghua Chen (Chapel Hill, North Carolina); Michael B. Duncan (Chapel Hill, North Carolina); Deepak Shukla (Skokie, Illinois); Vaibhav Tiwari (Chicago, Illinois); Anders Malmstrom (Lund, Sweden) |
| ABSTRACT | 3-OST-5 proteins, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to 3-OST-5 homologs, and methods of producing the same, are also disclosed. 3OST-5 gene products have biological activity in specific heparan sulfate 3-O-sulfotransferase reactions. These reactions provide unique modified heparan sulfate. Thus, therapeutic methods involving this activity are also disclosed. |
| FILED | Monday, July 07, 2003 |
| APPL NO | 10/520341 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531352 | Strober et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Warren Strober (Bethesda, Maryland); Kazuhiko Nakamura (Fukuoka, Japan); Atsushi Kitani (Rockville, Maryland); Ivan J. Fuss, Jr. (Bethesda, Maryland) |
| ABSTRACT | The present invention provides alternatives to traditional drug and surgical treatments for IBD. In particular, the present invention provides compositions and methods for the treatment of autoimmune diseases such as IBD in humans using TGF-β therapy. The compositions of the present invention provide vectors containing TGF-β under the control of an inducible promoter. In particularly preferred embodiments, the present invention provides regulated plasmid constructs capable of inducing TGF-β production. In preferred embodiments, the methods of the present invention utilize the vectors described for assaying the expression of a gene in a cell. In some preferred embodiments, the methods of the present invention utilize the administration of TGF-β containing vectors to treat IBD. In alternative preferred embodiments, the present invention provides methods and compositions for the induction of high-level interleukin (e.g., IL-10) production. |
| FILED | Friday, April 20, 2001 |
| APPL NO | 10/258109 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531354 | Stice et al. |
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| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Steve Stice (Athens, Georgia); Soojung Shin (Baltimore, Maryland); Sujoy Dhara (Athens, Georgia) |
| ABSTRACT | The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as well as methods for producing feeder cell-free samples of neuronal cells, preferably adherent human neuronal cells and the feeder cell-free neuronal cells themselves. Pharmaceutical compositions and methods of treating neurodegenerative diseases as well as the use of the described cells in assay systems is also described. |
| FILED | Wednesday, October 05, 2005 |
| APPL NO | 11/243819 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531355 | Rodríguez et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Larissa V. Rodríguez (Los Angeles, California); Ben Wu (Los Angeles, California) |
| ABSTRACT | This invention also provides a purified or isolated population of ADSCs that can differentiate into a cell of the leiomyogenic lineage, e.g., smooth muscle or skeletal muscle. In yet another aspect, the population additionally can be differentiated into a lineage selected from the group consisting of osteogenic, adipogenic, chondrogenic, myogenic and neuronal. This invention further provides a composition comprising a substantially homogeneous expanded population of smooth muscle cells. This invention provides a composition comprising a substantially homogeneous expanded population of skeletal muscle cells. Also provided herein is an isolated composition comprising a purified adipose-derived stem cell (ADSC) or progeny of said ADSC and an effective amount of laminin or heparin, effective to induce leiomyogenic differentiation. Diagnositic and therapeutic uses for these compositions are provided herein. |
| FILED | Friday, July 29, 2005 |
| APPL NO | 11/192753 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531356 | Kalin et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ned H. Kalin (Madison, Wisconsin); Patrick H. Roseboom (Madison, Wisconsin); Charles F. Landry (Madison, Wisconsin); Steven A. Nanda (Madison, Wisconsin) |
| ABSTRACT | The DNA sequences of human and rat CRF2α receptor promoters are disclosed. Certain functional fragments of the human CRF2α receptor promoter are also disclosed. Further disclosed are a method of identifying functional fragments of human and rat CRF2α receptor promoters and a method of identifying agents that can alter the activity of the human or rat CRF2α receptor promoter. |
| FILED | Monday, September 26, 2005 |
| APPL NO | 11/234916 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531366 | Abbott et al. |
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| ASSIGNEE(S) | Platypus Technologies, LLC (Madison, Wisconsin) |
| INVENTOR(S) | Nicholas Abbott (Madison, Wisconsin); Christopher Murphy (Madison, Wisconsin); Barbara Israel (Mt Horeb, Wisconsin); Doug Hansmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format. |
| FILED | Monday, January 09, 2006 |
| APPL NO | 11/328040 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/526 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531500 | Nadel et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jay A. Nadel (San Francisco, California); Kiyoshi Takeyama (Tokyo, Japan) |
| ABSTRACT | Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic molecule, an antibody, or portion of an antibody that binds to and blocks the EGF receptor. The EGF-R antagonist is preferably administered by injection in an amount sufficient to inhibit formation of goblet cells in pulmonary airways. The degranulation of goblet cells that results in airway mucus production is thereby inhibited. Assays for screening candidate agents that inhibit goblet cell proliferation are also provided. |
| FILED | Tuesday, November 28, 2006 |
| APPL NO | 11/564190 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531504 | Fasano |
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| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Alessio Fasano (West Friendship, Maryland) |
| ABSTRACT | Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the opening of mammalian tight junctions. |
| FILED | Tuesday, August 08, 2006 |
| APPL NO | 11/500429 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07531512 — Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes
| US 07531512 | Fasano et al. |
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| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Alessio Fasano (West Friendship, Maryland); Tammara L. Watts (Baltimore, Maryland) |
| ABSTRACT | A method for preventing or delaying the onset of autoimmune diseases is disclosed. |
| FILED | Friday, February 03, 2006 |
| APPL NO | 11/346395 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531514 | Fogelman et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Alan M. Fogelman (Beverly Hills, California); Gattadahalli M. Anantharamaiah (Birmingham, Alabama); Mohamad Navab (Los Angeles, California) |
| ABSTRACT | This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. In certain embodiments, the peptides comprise an 18 amino acid class A amphipathic helix with protecting groups on the amino and the carboxyl terminus. The peptides are highly stable, readily administered via an oral route, and effective to stimulate the formation and cycling of pre-beta high density lipoprotein-like particles, and/or to promote lipid transport and detoxification. When administered with a statin, the peptides enhance the activity of the statin permitting the statin to be used at significantly lower dosages and/or cause the statins to be significantly more anti-inflammatory at any given dose. |
| FILED | Tuesday, May 09, 2006 |
| APPL NO | 11/431412 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531518 | Vignery et al. |
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| ASSIGNEE(S) | Unigene Laboratories Inc. (Boonton, New Jersey); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Agnès Vignery (Branford, Connecticut); Nozer M. Mehta (Randolph, New Jersey); James P. Gilligan (Union, New Jersey) |
| ABSTRACT | A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided. |
| FILED | Wednesday, May 11, 2005 |
| APPL NO | 11/128095 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531541 | Conn et al. |
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| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | P. Jeffrey Conn (Brentwood, Tennessee); Alice L. Rodriguez (Nashville, Tennessee); Carrie K. Jones (Nashville, Tennessee) |
| ABSTRACT | Provided is a method of treating conditions and disorders for which full mGluR5 antagonists are potentially effective, such as, e.g., anxiety, epilepsy, schizophrenia and other psychotic disorders, Parkinson's disease, addictive disorders, and the like in a subject in need of such treatment, comprising administration to such subject of a therapeutically effective amount of a partial, non-competitive mGluR5 antagonist compound of the invention. Specific examples of partial MgluR5 antagonists provided include those compounds having the formula: wherein: Z is, independently N or —CH—, provided that one, and only one Z is N; R is halogen (e.g., Br, F and the like), alkyl (e.g., methyl), alkenyl (e.g., CH═CH2, aryl (e.g., phenyl), heterocyclic (e.g., thiophenyl). |
| FILED | Wednesday, September 20, 2006 |
| APPL NO | 11/523873 |
| ART UNIT | 1614 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531555 | Papke et al. |
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| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Roger L. Papke (Gainesville, Florida); Nicole A. Horenstein (Gainesville, Florida); Michael M. Francis (Salt Lake City, Utah); Kyung Il Choi (Seoul, South Korea) |
| ABSTRACT | The present invention concerns methods for treating or preventing neurological disorders characterized by dysfunction of nicotinic acetylcholine receptors by administering 2,2,6,6-tetramethylpiperidin-4-yl heptanoate (TMPH), or a pharmaceutically acceptable salt thereof, to the patient. In another aspect, the present invention pertains to pharmaceutical compositions containing TMPH, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. In another aspect, the present invention pertains to methods for selectively inhibiting nicotinic acetylcholine receptors that lack an α5, α6, or β3 subunit by contacting an effective amount of TMPH, or a pharmaceutically acceptable salt thereof, to the receptor. The method for selectively inhibiting nicotinic acethylcholine receptors that lack an α5 subunit can be carried out in vivo or in vitro. |
| FILED | Thursday, September 30, 2004 |
| APPL NO | 10/956957 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07531562 — Compositions and methods for protecting cells during cancer chemotherapy and radiotherapy
| US 07531562 | Fahl et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William E. Fahl (Madison, Wisconsin); Nalini Raghavachari (Madison, Wisconsin); Ming Zhu (Madison, Wisconsin); John A. Kink (Madison, Wisconsin) |
| ABSTRACT | Compositions, pharmaceutical preparations and methods are disclosed for protecting non-neoplastic cells from damage caused by cancer chemotherapeutic agents or radiation therapy, during the course of cancer therapy or bone marrow transplant. These are based on the use of chemoprotective inducing agents that induce or increase production of cellular detoxification enzymes in target cell populations. The compositions and methods are useful to reduce or prevent hair loss, gastrointestinal distress and lesions of the skin and oral mucosa that commonly occur in patients undergoing cancer therapy. Also disclosed is a novel assay system for identifying new chemoprotective inducing agents. |
| FILED | Wednesday, June 30, 2004 |
| APPL NO | 10/881028 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/365 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531563 | Bergeron |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Raymond J. Bergeron (Gainesville, Florida) |
| ABSTRACT | The present invention relates to novel thiazoline acids and derivatives thereof useful as chelators of trivalent metals in therapeutic applications. For example, the thiazoline acid derivatives are useful in diagnosing and treating pathological conditions associated with an excess of trivalent metals in humans and animals. |
| FILED | Friday, September 15, 2006 |
| APPL NO | 11/522299 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/365 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531621 | Dong et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Societe de Conseils de Recherches et d'Applications Scientifiques S.A.S. (Paris, France); Beth Israel (Boston, Massachusetts) |
| INVENTOR(S) | Zheng Xin Dong (Framingham, Massachusetts); Michael Chorev (Chestnut Hill, Massachusetts); Michael Rosenblatt (Newton Centre, Massachusetts) |
| ABSTRACT | This invention relates to a series of PTH and PTHrP analogues that selectively bind to PTH2 receptors and as such may be useful in treating abnormal CNS functions; abnormal pancreatic functions; divergence from normal mineral metabolism and homeostasis; male infertility; regulation of abnormal blood pressure; and hypothalmic disease. |
| FILED | Monday, May 03, 1999 |
| APPL NO | 09/674597 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531634 | Getzenberg |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Robert H. Getzenberg (Lutherville, Maryland) |
| ABSTRACT | Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and polynucleotide sequences encoding the NMPs, and particularly, those of BLCA-1, and antibodies thereto. |
| FILED | Friday, December 02, 2005 |
| APPL NO | 11/292278 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531635 | Nelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Lawrence M. Nelson (Burke, Virginia); Zhi-Bin Tong (Potomac, Maryland) |
| ABSTRACT | Disclosed herein are novel nucleic acid and protein sequences that are essential to fertility. In particular, human Mater cDNA and protein sequences are provided. Functional MATER is required for female fertility; zygotes that arise from Mater null oocytes do not progress beyond the two-cell stage. MATER-protein specific binding agents, such as antibodies, are described. Methods are described for detecting MATER protein in a subject, including methods for determining whether a subject has a biological condition associated with abnormal Mater expression. Also provided are kits for detecting MATER protein in a subject. |
| FILED | Tuesday, October 24, 2006 |
| APPL NO | 11/586160 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531649 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chi-Hong B. Chen (Los Angeles, California); Ralf Landgraf (Van Nuys, California) |
| ABSTRACT | The disclosure provided herein provides compositions of nucleic acid aptamers that bind human epidermal growth factor receptor-3 and methods for their use. |
| FILED | Friday, July 16, 2004 |
| APPL NO | 10/563888 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531662 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Li Deng (Newton Lower Falls, Massachusetts); Xiaofeng Liu (Waltham, Massachusetts) |
| ABSTRACT | One aspect of the present invention relates to cinchona-alkaloid-based catalysts. A second aspect of the invention relates to a method of preparing a derivatized cinchona alkaloid catalyst by reacting a cinchona-alkaloid with base and a compound that has a suitable leaving group. Another aspect of the present invention relates to a method of preparing a chiral, non-racemic compound from a prochiral cyclic anhydride or a meso cyclic anhydride, comprising the step of: reacting a prochiral cyclic anhydride or a meso cyclic anhydride with a nucleophile in the presence of a catalyst; wherein said prochiral cyclic anhydride or meso cyclic anhydride comprises an internal plane of symmetry or point of symmetry or both; thereby producing a chiral, non-racemic compound; wherein said catalyst is a derivatized cinchona-alkaloid. Yet another aspect of the present invention relates to a method of kinetic resolution, comprising the step of: reacting a racemic cyclic anhydride with an alcohol in the presence of a derivatized cinchona-alkaloid catalyst. |
| FILED | Thursday, June 10, 2004 |
| APPL NO | 10/865490 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531669 | Schubert et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | David R. Schubert (La Jolla, California); Yuanbin Liu (San Diego, California); Thomas Baiga (San Marcos, California) |
| ABSTRACT | In accordance with the present invention, there are provided novel compounds that protect neurons and/or promote neuroregeneration and/or promote memory formation. Such compounds are useful for treatment of a variety of neural disorders and conditions. In another aspect of the present invention, there are also provided formulations containing one or more of the above-described compounds, optionally further containing additional neurologically active compound(s) and/or adjuvants to facilitate delivery thereof across the blood/brain barrier. In still another aspect of the present invention, there are further provided methods for treating a wide variety of neurological indications, e.g., acute neural injuries, chronic injuries, promoting memory formation, and the like. |
| FILED | Friday, December 30, 2005 |
| APPL NO | 11/323987 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/375.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531713 | Blakely et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Randy D. Blakely (Brentwood, Tennessee); Richard Nass (Nashville, Tennessee); David Miller (Brentwood, Tennessee) |
| ABSTRACT | Provided are in vivo screening methods to detect and identify substances that affect neuronal viability, and/or prevent neurodegeneration, and/or confer neuroprotective effects The screening methods utilize recombinant C. elegans expressing a detectable marker in neuronal sub-groups and the use of neurotoxins specific to specific neuronal cells. Also provided are methods for identifying modulators of neurotransmitter transporters such as the dopamine transporter. Therefore, the invention provides methods for identifying substances that can be used in the prevention and therapy of neurodegenerative diseases. |
| FILED | Wednesday, January 05, 2005 |
| APPL NO | 11/029895 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533107 | Gupta et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amarnath Gupta (San Diego, California); Bertram Ludaescher (San Diego, California); Maryann E. Martone (La Jolla, California) |
| ABSTRACT | A method and program product for integrating different data sources has steps of obtaining semantic information from each of the different data sources (200, 202, 210), creating a conceptual model of (218, 220, 22) the data source using the semantic information, and accessing one or more secondary knowledge sources. The secondary information sources contain information regarding the relations of data from different of the databases, so that an integrated semantic model of all of the databases (200, 202, 210) may be created. Queries can then be processed using the integrated semantic model. |
| FILED | Friday, September 07, 2001 |
| APPL NO | 10/363615 |
| ART UNIT | 2164 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07530320 | Portmann |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Helmut Portmann (Panama City Beach, Florida) |
| ABSTRACT | An underwater water cannon defense system includes an underwater vehicle, a water cannon coupled to the vehicle, one or more nozzles mounted on the vehicle and directed away therefrom, and water distribution valving mounted in the vehicle that distributes pressurized water to the water cannon and the one or more nozzles in a controlled fashion. |
| FILED | Monday, July 16, 2007 |
| APPL NO | 11/894631 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/319 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07530952 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yongli Huang (San Jose, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | A capacitive ultrasonic transducer is described which include one or more cells including a cavity defined by a membrane electrode supported spaced from a support electrode by insulating walls with a patterned isolation layer having isolation posts or areas located in said cavity to prevent the electrodes for coming into contact during operation of the transducer, and to minimize the accumulation of charge as compared to a non-patterned isolation layer for preventing contact of the electrodes during operation of the transducer. |
| FILED | Thursday, April 01, 2004 |
| APPL NO | 10/817381 |
| ART UNIT | 3768 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Surgery 6/459 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531058 | Grose et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Douglas L. Grose (Algona, Washington); Marc J. Piehl (Renton, Washington); Douglas A. Frisch (Renton, Washington); Joseph L. Sweetin (Lake Forest Park, Washington); Gary J. Peffers (Pittsboro, Indiana) |
| ABSTRACT | A composite member with a reinforced rampdown or taper has a composite noodle bonded to an end of a core to fill the taper. |
| FILED | Thursday, February 24, 2005 |
| APPL NO | 11/065350 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/307.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531108 | Hampden-Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark J. Hampden-Smith (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); James Caruso (Albuquerque, New Mexico); Daniel J. Skamser (Simpsonville, South Carolina); Quint H. Powell (Albuquerque, New Mexico); Klaus Kunze (Albuquerque, New Mexico) |
| ABSTRACT | Photoluminescent phosphor powders and a method for making phosphor powders. The phosphor powders have a small particle size, narrow particle size distribution and are substantially spherical. The method of the invention advantageously permits the economic production of such powders. The invention also relates to improved devices, such as display devices and lighting elements, incorporating the phosphor powders. |
| FILED | Wednesday, February 21, 2007 |
| APPL NO | 11/677268 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions 252/301.360 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531132 | Delcomyn et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Carrie A. Delcomyn (Lynn Haven, Florida); Jean Renard (Panama City, Florida); William Wallace (Panama City, Florida); Michael Henley (Panama City, Florida) |
| ABSTRACT | A universal decontamination formulation and method is disclosed based on the in situ generation dioxirane(s) under non-corrosive neutral conditions for the neutralization of chemical and biological warfare (CBW) agents. The composition relates to the generation of dioxiranes by mixing a monopersulfate-containing compound in the presence of a ketone in water buffered with a carbonate-type buffer, producing a pH neutral formulation that provides effective reactivity towards CBW agents over a wide range of temperatures. |
| FILED | Tuesday, June 06, 2006 |
| APPL NO | 11/422504 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531181 | Danishefsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Samuel J. Danishefsky (Englewood, New Jersey); Vadim Dudkin (New York, New York); Xudong Geng (New York, New York); Mihirbaran Mandal (New York, New York); Isaac Kraus (New York, New York) |
| ABSTRACT | The present invention provides multi-antigenic constructs comprising one or more carbohydrate antigens having the formula: wherein R1, R2A, R2B, R3, R4, W1, W2 and W3 are as defined herein; and additionally provides compositions thereof, and methods for their use in the treatment and/or prevention of HIV infection, and methods for inducing HIV-specific antibodies in a subject, comprising administering to a subject in need thereof, an effective amount of any of the inventive compounds as disclosed herein, either in conjugated form or unconjugated and in combination with a suitable immunogenic carrier. In another aspect, the invention provides an antibody or antibody fragment which binds specifically to a gp120 glycan or glycopeptide of the invention. |
| FILED | Friday, June 03, 2005 |
| APPL NO | 11/145084 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531183 | Singh et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Shashi Kant Sharma (New Bedford, Massachusetts) |
| ABSTRACT | An isolated, biologically active 33 kDa Hemagglutinin purified from the type A Clostridium botulinum neurotoxin complex and its uses are described. |
| FILED | Tuesday, November 22, 2005 |
| APPL NO | 11/286515 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531210 | Archer, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Harry L. Archer, Jr. (Alexandria, Virginia) |
| ABSTRACT | A method of uniformly distributing liner on an interior of a tube includes providing an apparatus comprising a horizontal bed, a tailstock coupling mounted on the horizontal bed, a drive coupling and a drive unit connected to the drive coupling; mounting the tube in the tailstock and drive couplings; and spinning the tube using torque control of the drive unit. In one embodiment, the method includes dispensing a continuous bead of liner on the interior of the tube and spreading the liner on the interior of the tube using a brush. |
| FILED | Thursday, June 23, 2005 |
| APPL NO | 11/169258 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531293 | Afzali-Ardakani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ali Afzali-Ardakani (Ossining, New York); Cherie R. Kagan (Ossining, New York); Laura L. Kosbar (Mohegan Lake, New York); Sally A. Swanson (San Jose, California); Charan Srinivasan (State College, Pennsylvania) |
| ABSTRACT | The invention is directed to a radiation sensitive compound comprising a surface binding group proximate to one end of the compound for attachment to a substrate, and a metal binding group proximate to an opposite end of the compound. The metal binding group is not radiation sensitive. The radiation sensitive compound also includes a body portion disposed between the surface binding group and the metal binding group, and a radiation sensitive group positioned in the body portion or adjacent to the metal binding group. The surface binding group is capable of attaching to a substrate selected from a metal, a metal oxide, or a semiconductor material. |
| FILED | Friday, June 02, 2006 |
| APPL NO | 11/445326 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/296 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531307 | Wigler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Michael Wigler (Cold Spring Harbor, New York); Robert Lucito (Mineola, New York) |
| ABSTRACT | It is an object of the present invention to provide a solution to problems associated with the use of microarray technology for the analysis DNA. The present invention provides compositions and methods for the use of simple and compound representations of DNA in microarray technology. The present invention is also directed to methods for the production of High Complexity Representations (HCRs) of the DNA from cells. |
| FILED | Wednesday, March 30, 2005 |
| APPL NO | 11/094388 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531359 | Shenoy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Devanand Shenoy (McLean, Virginia); Elias Feresenbet (Allentown, Pennsylvania); Enrico Dalcanale (Parma, Italy); Susan Daly (Alexandria, Virginia) |
| ABSTRACT | The chemical compound: Each R1 is H or CH3. A device for detecting an analyte having: a substrate; a film on the substrate, a flow cell for delivering air containing the analyte to the film, and an apparatus for measuring the refractive index of the film. Each R2 is an alkyl group. Each X is O or S. |
| FILED | Wednesday, March 01, 2006 |
| APPL NO | 11/307966 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531363 | Cole et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Barrett E. Cole (Bloomington, Minnesota); Yuandong Gu (St. Paul, Minnesota) |
| ABSTRACT | Detection systems and methods for capturing and analyzing particles within a particle sample are provided. The detection system may include, for example, a particle concentrator that can be used to collect and concentrate particles on a sample collection surface, an energy source for providing energy to induce fluorescence in the particles, and a detector for detecting at least some fluorescence induced in the particles by the energy source. The detection system may include a heater and/or cooler for controlling the temperature of the particle sample during testing. |
| FILED | Tuesday, December 30, 2003 |
| APPL NO | 10/748398 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531702 | Davis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew C. Davis (Ridgecrest, California) |
| ABSTRACT | An environmentally friendly picric acid explosive comprising, providing a nitromalondialdehyde, providing a dinitroketone, reacting the nitromalondialdehydes with the dinitroketone to produce a mixture, and subjecting the mixture to a cyclodehydrative mechanism to produce environmentally friendly picric acid explosive. Embodiments of the present invention include the picric acid explosive produced by the methods of described above. |
| FILED | Monday, July 23, 2007 |
| APPL NO | 11/781837 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/711 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531802 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Xi-Cheng Zhang (Melrose, New York); Jianming Dai (Troy, New York); Xu Xie (Troy, New York) |
| ABSTRACT | A method of analyzing a remotely-located object includes the steps of inducing a volume of an ionized ambient gas to emit pulsed terahertz radiation directed toward a targeted object by focusing an optical pump beam in the volume and ionizing another volume of the ambient gas to produce a sensor plasma by focusing an optical probe beam in the other volume of ambient gas. The interaction, in the sensor plasma, of the focused optical probe beam and an incident terahertz wave, which is produced by the targeted object reflecting, scattering, or transmitting the pulsed terahertz radiation, produces a resultant radiation. Detecting an optical component of the resultant radiation emitted by the sensor plasma facilitates detection of a signature of the targeted object imposed onto the incident terahertz radiation. |
| FILED | Thursday, December 14, 2006 |
| APPL NO | 11/610824 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531830 | Kaiser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Christian Kaiser (San Jose, California); Stuart Stephen Papworth Parkin (San Jose, California) |
| ABSTRACT | A tunnel barrier in proximity with a layer of a rare earth element-transition metal (RE-TM) alloy forms a device that passes negatively spin-polarized current. The rare earth element includes at least one element selected from the group consisting of Gd, Tb, Dy, Ho, Er, Tm, and Yb. The RE and TM have respective sub-network moments such that the absolute magnitude of the RE sub-network moment is greater than the absolute magnitude of the TM sub-network moment. An additional layer of magnetic material may be used in combination with the tunnel barrier and the RE-TM alloy layer to form a magnetic tunnel junction. Still other layers of tunnel barrier and magnetic material may be used in combination with the foregoing to form a flux-closed double tunnel junction device. |
| FILED | Monday, April 23, 2007 |
| APPL NO | 11/739051 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531851 | Rajavel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Rajesh D. Rajavel (Oak Park, California); Mary Y. Chen (Oak Park, California); Steven S. Bui (Simi Valley, California); David H. Chow (Newbury Park, California); James Chingwei Li (Simi Valley, California); Mehran Mokhtari (Thousand Oaks, California); Marko Sokolich (Los Angeles, California) |
| ABSTRACT | An electronic device contains a substrate, a sub-collector supported by the substrate, an un-doped layer having a selectively implanted buried sub-collector and supported by the sub-collector, an As-based nucleation layer partially supported by the un-doped layer, a collector layer supported by the As-based nucleation layer, a base layer supported by the collector layer, an emitter layer and a base contact supported by the base layer, an emitter cap layer supported by the emitter layer, an emitter contact supported by the emitter cap layer, and a collector contact supported by the sub-collector. A method provides for selecting a first InP layer, forming an As-based nucleation layer on the first InP layer, and epitaxially growing a second InP layer on the As-based nucleation layer. |
| FILED | Wednesday, February 28, 2007 |
| APPL NO | 11/713070 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/197 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531908 | Fries et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | David P. Fries (St. Petersburg, Florida); Chad Lembke (St. Petersburg, Florida) |
| ABSTRACT | Activation of a propellant in a constant volume container causes a phase change material to rapidly expand so that the pressure in the container increases. Programmability and sequential actuation are enabled by patterning the phase change material into the integrated device. The pressure generated may be used to activate an energy transducer such as a high pressure turbine, a piezoelectric material, and an elastic strain material. This provides a hybrid actuation system of electrical energy, pneumatic and hydraulic power. The pressure change in the constant volume container is also harnessed to provide a microbattery. |
| FILED | Thursday, September 07, 2006 |
| APPL NO | 11/470854 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Prime-mover dynamo plants 290/1.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532093 | Pulskamp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey S. Pulskamp (McLean, Virginia); Ronald G. Polcawich (Derwood, Maryland); Daniel Judy (Odenton, Maryland) |
| ABSTRACT | A microelectromechanical system (MEMS) switch comprising a radio frequency (RF) transmission line; a structurally discontinuous RF conductor adjacent to the RF transmission line; a pair of cantilevered piezoelectric actuators flanking the RF conductor; a contact pad connected to the pair of cantilevered piezoelectric actuators; a pair of cantilevered structures connected to the RF conductor; a plurality of air bridges connected to the pair of cantilevered piezoelectric actuators; and a plurality of contact dimples on the contact pad. Preferably, the RF transmission line comprises a pair of co-planar waveguide ground planes flanking the RF conductor; and a plurality of ground straps connected to the pair of co-planar waveguide ground planes, wherein the RF transmission line is operable to provide a path along which RF signals propagate. |
| FILED | Thursday, September 07, 2006 |
| APPL NO | 11/518746 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532150 | Abatzoglou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Theagenis J. Abatzoglou (Huntington Beach, California); Leo H. Hui (Alhambra, California) |
| ABSTRACT | A moving radar generates a search mode synthetic aperture image of a patch having a principal scatterer. The boundaries of the patch are from R0 to R1 slant range and θ0 to θ1 azimuth angle. A computer motion compensates digital samples to obtain a motion compensated digital array. The motion compensated digital array is converted to a frequency array in the frequency domain Kx, Ky The frequency array has a rectangular aperture extending ΔKx and ΔKy. Available samples from the frequency array are computed using a Range Migration Algorithm including a Stolt interpolation. Usable samples are identified from the available samples using one or more criteria. Usable samples are removed from available samples to obtain incomplete samples. Features related to the patch having a principal scatterer are extracted from the usable samples. The features are used to extrapolate extrapolated samples from the usable samples. The extrapolated samples, the usable samples and the incomplete samples are combined to compute the image of the patch and principal scatterer. Incomplete samples are substituted where they overlap interpolated samples. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/077669 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.F00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532379 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | David A. B. Miller (Stanford, California); Jonathan E. Roth (Stanford, California) |
| ABSTRACT | An electro-optic semiconductor device (e.g., an optical modulator) having side access and beam propagation within the device is provided. Side access for the optical input and/or output facilitates disposition of electronic circuitry and/or heat sinking structures on the top and bottom surfaces of the modulator. Internal beam propagation instead of internal waveguiding advantageously simplifies optical coupling and alignment to the modulator. Interaction length within the device is preferably enhanced by passing through the device active region at a relatively shallow angle. The internally propagating beam is reflected from a reflective face parallel to the device active region. The side faces can be perpendicular or tilted with respect to the reflective face. Tilted side faces are preferably tilted to provide external beam paths parallel to the reflective face. Internal reflection from an angled side face can be employed to provide configurations having one side port and one top or bottom port. |
| FILED | Tuesday, September 19, 2006 |
| APPL NO | 11/524498 |
| ART UNIT | 2873 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optical: Systems and elements 359/245 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532621 | Birman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Kenneth Paul Birman (Ithaca, New York); Mahesh Balakrishnan (Ithaca, New York) |
| ABSTRACT | A system and method for providing a low-latency reliable multicast protocol designed for time-critical clustered applications. Internet Protocol (IP) multicast is used to transmit data and recovers from packet loss in end-hosts using a repair mechanism involving the exchange of XOR repairs between receivers and across groups. The system and method of the present invention can be embodied in a scalable, reliable and fast multicast primitive that can be layered under high-level abstractions such as publish-subscribe, group communication and replicated service/object infrastructures. |
| FILED | Wednesday, August 30, 2006 |
| APPL NO | 11/513006 |
| ART UNIT | 2419 — Selective Visual Display Systems |
| CURRENT CPC | Multiplex communications 370/389 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532623 | Rosenzweig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | BBN Technologies Corp. (Cambridge, Massachusetts) |
| INVENTOR(S) | Vladimir Rosenzweig (Belmont, Massachusetts); Cesar A. Santivanez (Boston, Massachusetts); Joseph J. Weinstein (Somerville, Massachusetts); Daniel A. Coffin (Sudbury, Massachusetts) |
| ABSTRACT | The invention relates generally to systems, methods and/or devices for joining, generating, maintaining, and/or multicasting information via a multicast mesh. |
| FILED | Wednesday, March 23, 2005 |
| APPL NO | 11/088045 |
| ART UNIT | 2419 — Selective Visual Display Systems |
| CURRENT CPC | Multiplex communications 370/390 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532650 | Nettleton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of the Army (Washington, District of Columbia) |
| INVENTOR(S) | John E. Nettleton (Fairfax Station, Virginia); Dallas N. Barr (Woodbridge, Virginia) |
| ABSTRACT | A monoblock laser cavity includes a plurality of discrete optical components disposed serially on a substrate and sharing a common optical axis. The optical components include a laser rod of gain material, a Q-switch, an OPO crystal, and an output coupler. The output coupler has at least one convex end face to improve the beam quality. |
| FILED | Wednesday, March 14, 2007 |
| APPL NO | 11/686336 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532919 | Soyemi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Olusola O. Soyemi (Longmont, Colorado); Babs R. Soller (Northboro, Massachusetts); Ye Yang (Worcester, Massachusetts) |
| ABSTRACT | Methods and systems for calculating tissue oxygenation, e.g., oxygen saturation, in a target tissue are disclosed. In some embodiments, the methods include: (a) directing incident radiation to a target tissue and determining reflectance spectra of the target tissue by measuring intensities of reflected radiation from the target tissue at a plurality of radiation wavelengths; (b) correcting the measured intensities of the reflectance spectra to reduce contributions thereto from skin and fat layers through which the incident radiation propagates; (c) determining oxygen saturation in the target tissue based on the corrected reflectance spectra; and (d) outputting the determined value of oxygen saturation. |
| FILED | Wednesday, May 30, 2007 |
| APPL NO | 11/755643 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533013 | Marcu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Daniel Marcu (Culver City, California) |
| ABSTRACT | Machine translation decoding is accomplished by receiving as input a text segment in a source language to be translated into a target language, generating an initial translation as a current target language translation, applying one or more modification operators to the current target language translation to generate one or more modified target language translations, determining whether one or more of the modified target language translations represents an improved translation in comparison with the current target language translation, setting a modified target language translation as the current target language translation, and repeating these steps until occurrence of a termination condition. Automatically generating a tree (e.g., either a syntactic tree or a discourse tree) can be accomplished by receiving as input a tree corresponding to a source language text segment, and applying one or more decision rules to the received input to generate a tree corresponding to a target language text segment. |
| FILED | Friday, May 11, 2001 |
| APPL NO | 09/854327 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533071 | Snook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Neurosciences Research Foundation, Inc. (San Diego, California) |
| INVENTOR(S) | James A. Snook (San Diego, California); Donald B. Hutson (San Diego, California); Jeffrey L. Krichmar (Cardiff-by-the-Sea, California) |
| ABSTRACT | A special purpose processor (SPP) can use a Field Programmable Gate Array (FPGA) or similar programmable device to model a large number of neural elements. The FPGAs can have multiple cores doing presynaptic, postsynaptic, and plasticity calculations in parallel. Each core can implement multiple neural elements of the neural model. |
| FILED | Tuesday, June 27, 2006 |
| APPL NO | 11/426881 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533226 | Flautner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ARM Limited (Cambridge, United Kingdom); University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Krisztian Flautner (Cambridge, United Kingdom); David T. Blaauw (Ann Arbor, Michigan); Trevor N. Mudge (Ann Arbor, Michigan); Nam S. Kim (Ann Arbor, Michigan); Steven M. Martin (Ann Arbor, Michigan) |
| ABSTRACT | A memory circuit for use in a data processing circuit is described, in which memory cells have at least two states, each state being determined by both a first voltage level corresponding to a first supply line and a second voltage level corresponding to a second supply line. The memory circuit comprises a readable state in which information stored in a memory cell is readable and an unreadable state in which information stored in said memory cell is reliably retained but unreadable. Changing the first voltage level but keeping the second voltage level substantially constant effects a transition between the readable state and the unreadable state. In use, the static power consumption of the memory cell in the unreadable state is less than static power consumption of the memory cell in the readable state. |
| FILED | Tuesday, February 14, 2006 |
| APPL NO | 11/353024 |
| ART UNIT | 2187 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/156 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D592318 | Ruegsegger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | APG West, Inc. (Phoenix, Arizona) |
| INVENTOR(S) | Jack Ruegsegger (Glendale, Arizona) |
| ABSTRACT | |
| FILED | Friday, October 12, 2007 |
| APPL NO | 29/292487 |
| ART UNIT | 2914 — Design |
| CURRENT CPC | Building units and construction elements D25/113 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07530259 | Tai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Yu-Chong Tai (Pasadena, California); Jun Xie (Pasadena, California); Chi-yuan Shih (Pasadena, California); Qing He (Pasadena, California) |
| ABSTRACT | An apparatus for liquid chromatography comprises a liquid chromatography separation column on a substrate, wherein the separation column is coupled to a heater on the substrate. A chip-based temperature controlled liquid chromatography device comprises a substrate, a thermal isolation zone, and a separation column thermally isolated from the substrate by the thermal isolation zone. An apparatus for chip-based liquid chromatography comprising a cooling device is provided. A temperature gradient liquid chromatography system comprises a chip-based temperature controlled liquid chromatography device, a fluidic coupling, and an electrical interface. Methods of making and methods of using of chip-based temperature gradient liquid chromatography devices are also provided. |
| FILED | Thursday, February 17, 2005 |
| APPL NO | 11/059625 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/61.570 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531149 | Peng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Xiaogang Peng (Fayetteville, Arkansas); Yongfen Chen (Fayetteville, Arkansas); Nikhil Jana (Singapore, Singapore); Arun Narayanaswamy (Fayetteville, Arkansas) |
| ABSTRACT | A general, reproducible, and simple synthetic method that employs readily available chemicals permits control of the size, shape, and size distribution of metal oxide nanocrystals. The synthesis entails reacting a metal fatty acid salt, the corresponding fatty acid, and a hydrocarbon solvent, with the reaction product being pyrolyzed to the metal oxide. Nearly monodisperse oxide nanocrystals of Fe3O4, Cr2O3, MnO, Co3O4, NiO, ZnO, SnO2, and In2O3, in a large size range (3-50 nm), are described. Size and shape control of the nanocrystals is achieved by varying the reactivity and concentration of the precursors. |
| FILED | Tuesday, August 16, 2005 |
| APPL NO | 11/204766 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531191 | Zion et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Todd C. Zion (Allston, Massachusetts); Andrey Zarur (Winchester, Massachusetts); Jackie Y. Ying (Winchester, Massachusetts) |
| ABSTRACT | A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic agent is released as the cross-linked polymer degrades. |
| FILED | Wednesday, December 17, 2003 |
| APPL NO | 10/740436 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/488 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531786 | Cunningham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Universiy of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Brian T. Cunningham (Champaign, Illinois); Charles Choi (Savoy, Illinois) |
| ABSTRACT | Photonic crystal (PC) sensors, and sensor arrays and sensing systems incorporating PC sensors are described which have integrated fluid containment and/or fluid handling structures. Sensors and sensing systems of the present disclosure are capable of high throughput sensing of analytes in fluid samples, bulk refractive index detection, and label-free detection of a range of molecules, including biomolecules and therapeutic candidates. The present disclosure also provides a commercially attractive fabrication platform for making photonic crystal sensors and systems wherein an integrated fluid containment structure and a photonic crystal structure are fabricated in a single molding or imprinting processing step amendable to high throughput processing. |
| FILED | Tuesday, November 06, 2007 |
| APPL NO | 11/983108 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/214.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531802 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Xi-Cheng Zhang (Melrose, New York); Jianming Dai (Troy, New York); Xu Xie (Troy, New York) |
| ABSTRACT | A method of analyzing a remotely-located object includes the steps of inducing a volume of an ionized ambient gas to emit pulsed terahertz radiation directed toward a targeted object by focusing an optical pump beam in the volume and ionizing another volume of the ambient gas to produce a sensor plasma by focusing an optical probe beam in the other volume of ambient gas. The interaction, in the sensor plasma, of the focused optical probe beam and an incident terahertz wave, which is produced by the targeted object reflecting, scattering, or transmitting the pulsed terahertz radiation, produces a resultant radiation. Detecting an optical component of the resultant radiation emitted by the sensor plasma facilitates detection of a signature of the targeted object imposed onto the incident terahertz radiation. |
| FILED | Thursday, December 14, 2006 |
| APPL NO | 11/610824 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531892 | Pfefferle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Lisa Pfefferle (Branford, Connecticut); Dragos Ciuparu (New Haven, Connecticut) |
| ABSTRACT | A process for growth of boron-based nanostructures, such as nanotubes and nanowires, with a controlled diameter and with controlled chemical (such as composition, doping) as well as physical (such as electrical and superconducting) properties is described. The boron nanostructures are grown on a metal-substituted MCM-41 template with pores having a uniform pore diameter of less than approximately 4 nm, and can be doped with a Group Ia or Group IIa electron donor element during or after growth of the nanostructure. Preliminary data based on magnetic susceptibility measurements suggest that Mg-doped boron nanotubes have a superconducting transition temperature on the order of 100 K. |
| FILED | Monday, December 13, 2004 |
| APPL NO | 11/011504 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/661 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532384 | Bermel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter Bermel (Cambridge, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | A phase shifter includes at least one photonic crystal structure having alternating high and low index dielectric layers. At least two defect structures are positioned between said photonic crystal structures. The defect structure includes one or more nonlinear materials used to produce an index change, whose effect is amplified to produce a specified phase shift in the output signal of said phase shifter. |
| FILED | Wednesday, November 15, 2006 |
| APPL NO | 11/560129 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532621 | Birman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Kenneth Paul Birman (Ithaca, New York); Mahesh Balakrishnan (Ithaca, New York) |
| ABSTRACT | A system and method for providing a low-latency reliable multicast protocol designed for time-critical clustered applications. Internet Protocol (IP) multicast is used to transmit data and recovers from packet loss in end-hosts using a repair mechanism involving the exchange of XOR repairs between receivers and across groups. The system and method of the present invention can be embodied in a scalable, reliable and fast multicast primitive that can be layered under high-level abstractions such as publish-subscribe, group communication and replicated service/object infrastructures. |
| FILED | Wednesday, August 30, 2006 |
| APPL NO | 11/513006 |
| ART UNIT | 2419 — Selective Visual Display Systems |
| CURRENT CPC | Multiplex communications 370/389 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533107 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amarnath Gupta (San Diego, California); Bertram Ludaescher (San Diego, California); Maryann E. Martone (La Jolla, California) |
| ABSTRACT | A method and program product for integrating different data sources has steps of obtaining semantic information from each of the different data sources (200, 202, 210), creating a conceptual model of (218, 220, 22) the data source using the semantic information, and accessing one or more secondary knowledge sources. The secondary information sources contain information regarding the relations of data from different of the databases, so that an integrated semantic model of all of the databases (200, 202, 210) may be created. Queries can then be processed using the integrated semantic model. |
| FILED | Friday, September 07, 2001 |
| APPL NO | 10/363615 |
| ART UNIT | 2164 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533294 | Mishra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Prabhat Mishra (Gainesville, Florida); Nikil Dutt (Irvine, California) |
| ABSTRACT | A functional coverage based test generation technique for pipelined architectures is presented. A general graph-theoretic model is developed that can capture the structure and behavior (instruction-set) of a wide variety of pipelined processors. A functional fault model is developed and used to define the functional coverage for pipelined architectures. Test generation procedures are developed that accept the graph model of the architecture as input and generate test programs to detect all the faults in the functional fault model. A graph model of the pipelined processor is automatically generated from the specification using functional abstraction. Functional test programs are generated based on the coverage of the pipeline behavior. Module level property checking is used to reduce test generation time. |
| FILED | Friday, September 09, 2005 |
| APPL NO | 11/223784 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07530156 | Rippel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Aerovironment Inc. (Monrovia, California) |
| INVENTOR(S) | Wally E. Rippel (Altadena, California); Daryl M. Kobayashi (Monrovia, California) |
| ABSTRACT | An electric motor, transformer or inductor having a cooling system. A stack of laminations have apertures at least partially coincident with apertures of adjacent laminations. The apertures define straight or angled cooling-fluid passageways through the lamination stack. Gaps between the adjacent laminations are sealed by injecting a heat-cured sealant into the passageways, expelling excess sealant, and heat-curing the lamination stack. Manifold members adjoin opposite ends of the lamination stack, and each is configured with one or more cavities to act as a manifold to adjacent passageway ends. Complex manifold arrangements can create bidirectional flow in a variety of patterns. |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/242823 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/596 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07530312 | Roesler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Alexander W. Roesler (Tijeras, New Mexico); Susan M. Wooden (Sandia Park, New Mexico) |
| ABSTRACT | Microelectromechanical (MEM) safe-arm devices comprise a substrate upon which a sense mass, that can contain an energetic material, is constrained to move along a pathway defined by a track disposed on the surface of the substrate. The pathway has a first end comprising a “safe” position and a second end comprising an “armed” position, whereat the second end the sense mass can be aligned proximal to energetic materials comprising the explosive train, within an explosive component. The sense mass can be confined in the safe position by a first latch, operable to release the sense mass by an acceleration acting in a direction substantially normal to the surface of the substrate. A second acceleration, acting in a direction substantially parallel to the surface of the substrate, can cause the sense mass to traverse the pathway from the safe position to the armed position. |
| FILED | Wednesday, June 14, 2006 |
| APPL NO | 11/452874 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/249 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07530607 | Luft |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter A. Luft (El Cerrito, California) |
| ABSTRACT | A coupling for mechanically connecting modular tubular struts of a positioning apparatus or space frame, comprising a pair of toothed rings (10, 12) attached to separate strut members (16), the teeth (18, 20) of the primary rings (10, 12) mechanically interlocking in both an axial and circumferential manner, and a third part comprising a sliding, toothed collar (14) the teeth (22) of which interlock the teeth (18, 20) of the primary rings (10, 12), preventing them from disengaging, and completely locking the assembly together. A secondary mechanism provides a nesting force for the collar, and/or retains it. The coupling is self-contained and requires no external tools for installation, and can be assembled with gloved hands in demanding environments. No gauging or measured torque is required for assembly. The assembly can easily be visually inspected to determine a “go” or “no-go” status. The coupling is compact and relatively light-weight. Because of it's triply interlocking teeth, the connection is rigid. The connection does not primarily rely on clamps, springs or friction based fasteners, and is therefore reliable in fail-safe applications. |
| FILED | Friday, January 06, 2006 |
| APPL NO | 11/327815 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipe joints or couplings 285/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07530785 | Deering et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Wind Turbine Company (Bellevue, Washington) |
| INVENTOR(S) | Kenneth J. Deering (Seattle, Washington); Keith P. Wohlwend (Issaquah, Washington) |
| ABSTRACT | A wind turbine with improved response to wind conditions is provided. Blade flap angle motion is accompanied by a change in pitch angle by an amount defining a pitch/flap coupling ratio. The coupling ratio is non-constant as a function of a flap angle and is preferably a substantially continuous, non-linear function of flap angle. The non-constant coupling ratio can be provided by mechanical systems such as a series of linkages or by configuring electronic or other control systems and/or angle sensors. A link with a movable proximal end advantageously is part of the mechanical system. The system can provide relatively large coupling ratios and relatively large rates of coupling ratio changes especially for near-feather pitches and low flap angles. |
| FILED | Wednesday, April 13, 2005 |
| APPL NO | 11/106133 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531034 | Howe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Beth Ann Howe (Lewistown, Illinois); Jesus Guadalupe Chaps-Cabrera (Coahuila, Mexico) |
| ABSTRACT | A metal-phosphate binder is provided. The binder may include an aqueous phosphoric acid solution, a metal-cation donor including a metal other than aluminum, an aluminum-cation donor, and a non-carbohydrate electron donor. |
| FILED | Tuesday, May 31, 2005 |
| APPL NO | 11/142530 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions: Coating or plastic 16/691 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07531808 — Method for the depth corrected detection of ionizing events from a co-planar grids sensor
| US 07531808 | De Geronimo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Gianluigi De Geronimo (Syosset, New York); Aleksey E. Bolotnikov (South Setauket, New York); Gabriella Carini (Port Jefferson, New York) |
| ABSTRACT | A method for the detection of ionizing events utilizing a co-planar grids sensor comprising a semiconductor substrate, cathode electrode, collecting grid and non-collecting grid. The semiconductor substrate is sensitive to ionizing radiation. A voltage less than 0 Volts is applied to the cathode electrode. A voltage greater than the voltage applied to the cathode is applied to the non-collecting grid. A voltage greater than the voltage applied to the non-collecting grid is applied to the collecting grid. The collecting grid and the non-collecting grid are summed and subtracted creating a sum and difference respectively. The difference and sum are divided creating a ratio. A gain coefficient factor for each depth (distance between the ionizing event and the collecting grid) is determined, whereby the difference between the collecting electrode and the non-collecting electrode multiplied by the corresponding gain coefficient is the depth corrected energy of an ionizing event. Therefore, the energy of each ionizing event is the difference between the collecting grid and the non-collecting grid multiplied by the corresponding gain coefficient. The depth of the ionizing event can also be determined from the ratio. |
| FILED | Thursday, January 25, 2007 |
| APPL NO | 11/626919 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/370.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532700 | Gara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alan G. Gara (Mount Kisco, New York); Valentina Salapura (Chappaqua, New York) |
| ABSTRACT | A hybrid counter array device for counting events. The hybrid counter array includes a first counter portion comprising N counter devices, each counter device for receiving signals representing occurrences of events from an event source and providing a first count value corresponding to a lower order bits of the hybrid counter array. The hybrid counter array includes a second counter portion comprising a memory array device having N addressable memory locations in correspondence with the N counter devices, each addressable memory location for storing a second count value representing higher order bits of the hybrid counter array. A control device monitors each of the N counter devices of the first counter portion and initiates updating a value of a corresponding second count value stored at the corresponding addressable memory location in the second counter portion. Thus, a combination of the first and second count values provide an instantaneous measure of number of events received. |
| FILED | Monday, August 21, 2006 |
| APPL NO | 11/507310 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Electrical pulse counters, pulse dividers, or shift registers: Circuits and systems 377/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07531775 | Strawa |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Anthony W. Strawa (San Jose, California) |
| ABSTRACT | A photometer that tracks a path of a moving light source with little or no motion of the photometer components. The system includes a non-moving, truncated paraboloid of revolution, having a paraboloid axis, a paraboloid axis, a small entrance aperture, a larger exit aperture and a light-reflecting inner surface, that receives and reflects light in a direction substantially parallel to the paraboloid axis. The system also includes a light processing filter to receive and process the redirected light, and to issue the processed, redirected light as processed light, and an array of light receiving elements, at least one of which receives and measures an associated intensity of a portion of the processed light. The system tracks a light source moving along a path and produces a corresponding curvilinear image of the light source path on the array of light receiving elements. Undesired light wavelengths from the light source may be removed by coating a selected portion of the reflecting inner surface or another light receiving surface with a coating that absorbs incident light in the undesired wavelength range. |
| FILED | Friday, September 30, 2005 |
| APPL NO | 11/251006 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Radiant energy 250/203.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531809 | Capote et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Creative Electron, Inc. (San Marcos, California) |
| INVENTOR(S) | M. Albert Capote (Carlsbad, California); Howard A. Lenos (Murrieta, California) |
| ABSTRACT | A radiation detector assembly has a semiconductor detector array substrate of CdZnTe or CdTe, having a plurality of detector cell pads on a first surface thereof, the pads having a contact metallization and a solder barrier metallization. An interposer card has planar dimensions no larger than planar dimensions of the semiconductor detector array substrate, a plurality of interconnect pads on a first surface thereof, at least one readout semiconductor chip and at least one connector on a second surface thereof, each having planar dimensions no larger than the planar dimensions of the interposer card. Solder columns extend from contacts on the interposer first surface to the plurality of pads on the semiconductor detector array substrate first surface, the solder columns having at least one solder having a melting point or liquidus less than 120 degrees C. An encapsulant is disposed between the interposer circuit card first surface and the semiconductor detector array substrate first surface, encapsulating the solder columns, the encapsulant curing at a temperature no greater than 120 degrees C. |
| FILED | Tuesday, April 10, 2007 |
| APPL NO | 11/783505 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/370.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532919 | Soyemi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Olusola O. Soyemi (Longmont, Colorado); Babs R. Soller (Northboro, Massachusetts); Ye Yang (Worcester, Massachusetts) |
| ABSTRACT | Methods and systems for calculating tissue oxygenation, e.g., oxygen saturation, in a target tissue are disclosed. In some embodiments, the methods include: (a) directing incident radiation to a target tissue and determining reflectance spectra of the target tissue by measuring intensities of reflected radiation from the target tissue at a plurality of radiation wavelengths; (b) correcting the measured intensities of the reflectance spectra to reduce contributions thereto from skin and fat layers through which the incident radiation propagates; (c) determining oxygen saturation in the target tissue based on the corrected reflectance spectra; and (d) outputting the determined value of oxygen saturation. |
| FILED | Wednesday, May 30, 2007 |
| APPL NO | 11/755643 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07531183 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Shashi Kant Sharma (New Bedford, Massachusetts) |
| ABSTRACT | An isolated, biologically active 33 kDa Hemagglutinin purified from the type A Clostridium botulinum neurotoxin complex and its uses are described. |
| FILED | Tuesday, November 22, 2005 |
| APPL NO | 11/286515 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07531716 | Polston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Jane E. Polston (Gainesville, Florida); Ernest Hiebert (Gainesville, Florida) |
| ABSTRACT | The subject invention concerns materials and methods for providing genetically-engineered resistance in plants to tomato yellow leaf curl geminivirus using a truncated version of the replication associated protein (Rep) gene of TYLCV. Virus-resistant plants produced according to the present invention have horticulturally acceptable phenotypic traits. Methods of the invention comprise transforming a plant with a polynucleotide wherein when the polynucleotide is expressed in the plant, the transformed plant exhibits resistance to plant viral infections. An exemplified embodiment utilizes a polynucleotide comprising a truncated Rep gene derived from a Florida isolate of TYLCV-Is. The methods of the invention can be used to provide resistance to TYLCV infection in plants such as tomato and tobacco. The present invention also concerns transformed and transgenic plants and plant tissue that express a polynucleotide comprising a truncated Rep gene of TYLCV. |
| FILED | Tuesday, May 07, 2002 |
| APPL NO | 10/477240 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 07531382 | Fitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | John L. Fitz (Baltimore, Maryland); Harris Turk (Baltimore, Maryland) |
| ABSTRACT | A method of creating a patterned device by selecting a substrate; depositing a mask layer on the substrate; forming a first step on the mask layer; depositing a sacrificial layer along the first step and the mask layer; depositing a blocking layer on the sacrificial layer; removing a portion of the blocking layer, where a portion of the blocking layer remains such that no gap exists between the blocking layer and the sacrificial layer and the remaining blocking layer is adhered to the mask layer; removing a portion of the sacrificial layer such that a gap is created between the blocking layer and the first step, where a portion of the sacrificial layer remains such that the blocking layer adhered to the mask layer remains; etching the mask layer beneath the gap; and processing the substrate through the gap in the mask layer. |
| FILED | Tuesday, April 22, 2008 |
| APPL NO | 12/152115 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07533013 | Marcu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Daniel Marcu (Culver City, California) |
| ABSTRACT | Machine translation decoding is accomplished by receiving as input a text segment in a source language to be translated into a target language, generating an initial translation as a current target language translation, applying one or more modification operators to the current target language translation to generate one or more modified target language translations, determining whether one or more of the modified target language translations represents an improved translation in comparison with the current target language translation, setting a modified target language translation as the current target language translation, and repeating these steps until occurrence of a termination condition. Automatically generating a tree (e.g., either a syntactic tree or a discourse tree) can be accomplished by receiving as input a tree corresponding to a source language text segment, and applying one or more decision rules to the received input to generate a tree corresponding to a target language text segment. |
| FILED | Friday, May 11, 2001 |
| APPL NO | 09/854327 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07532435 | Dugas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Research Corporation (White Bear Lake, Minnesota) |
| INVENTOR(S) | Matthew P. Dugas (St. Paul, Minnesota); Jeffrey A. Wallhoff (New Brighton, Minnesota) |
| ABSTRACT | An optical path or waveguide for a laser-assisted transducing head is disclosed. The optical path extends between the poles of the transducing head to near the write gap. A solid-state laser is attached to or incorporated into the slider or head and is positioned to direct thermal energy through a waveguide and onto a track of a read/write surface to lower the coercivity of the recording medium to facilitate the write process. |
| FILED | Tuesday, January 10, 2006 |
| APPL NO | 11/328847 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Dynamic magnetic information storage or retrieval 360/125.740 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 07532161 | Hsu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Po-Hsin Hsu (Irvine, California); Laura A. Cheung (Pasadena, California); Mohinder S. Grewal (Anaheim Hills, California) |
| ABSTRACT | Methods and apparatus for receiving an estimate of L1 iono delay and L1 iono delay rate, receiving GEO slant ionospheric delay, receiving user iono vertical error information for a GEO satellite, and computing a L1/L5 bias estimate from the estimate of L1 iono delay and L1 iono delay rate and GEO slant ionosperic delay. A wide area augmentation system (WAAS) includes L1/L5 bias estimation. The L1/L5 bias is the differential bias between the WAAS GEO satellite L1 and L5 signals. The data used in the L1/L5 bias estimation include the GEO L1 ionospheric delay estimated from a Kalman filter, and the GEO slant ionospheric delay calculated from the Ionospheric Grid Point (IGP) information in a WAAS message. The Sigma User Ionospheric Vertical Error (UIVE) is used as one of the conditions for performing the L1/L5 bias estimation. |
| FILED | Thursday, September 22, 2005 |
| APPL NO | 11/232575 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/358 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 07532150 | Abatzoglou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Theagenis J. Abatzoglou (Huntington Beach, California); Leo H. Hui (Alhambra, California) |
| ABSTRACT | A moving radar generates a search mode synthetic aperture image of a patch having a principal scatterer. The boundaries of the patch are from R0 to R1 slant range and θ0 to θ1 azimuth angle. A computer motion compensates digital samples to obtain a motion compensated digital array. The motion compensated digital array is converted to a frequency array in the frequency domain Kx, Ky The frequency array has a rectangular aperture extending ΔKx and ΔKy. Available samples from the frequency array are computed using a Range Migration Algorithm including a Stolt interpolation. Usable samples are identified from the available samples using one or more criteria. Usable samples are removed from available samples to obtain incomplete samples. Features related to the patch having a principal scatterer are extracted from the usable samples. The features are used to extrapolate extrapolated samples from the usable samples. The extrapolated samples, the usable samples and the incomplete samples are combined to compute the image of the patch and principal scatterer. Incomplete samples are substituted where they overlap interpolated samples. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/077669 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.F00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07530174 | Kimball et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Interior (Washington, District of Columbia) |
| INVENTOR(S) | Scott Andrew Kimball (Pass Christian, Mississippi); Edward C. Vaughn (Slidell, Louisiana) |
| ABSTRACT | A level assembly for a wading rod used to measure current flow velocity of a wadable body of water, such as a stream or a river. The level assembly includes a level body that is attached to the hexagonal or depth rod of the wading rod at a desired position using a fastener. The level body has a level indicator to determine whether the wading rod is plumb. An alignment bar is attached to the level body and positioned parallel to a wading tagline to aid in maintaining a perpendicular orientation of the wading rod. The level assembly can be repositioned by loosening the fastener, sliding it up or down the depth rod, and re-tightening the fastener at another desired position. The level assembly is used to maintain a level and perpendicular orientation of the top setting wading rod to the tagline, enabling more accurate flow velocity measurements. |
| FILED | Thursday, July 19, 2007 |
| APPL NO | 11/780385 |
| ART UNIT | 2841 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Geometrical instruments 033/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532635 | Kumar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sanjeev Kumar (Edinburg, Texas) |
| ABSTRACT | Systems and methods are described for high-speed memory assignment schemes for routing packets in a sharable parallel memory module based switch system. A method includes receiving a parameter, determining availability of memory location, determining if an available memory location is pre-assigned, and assigning a packet a parameter if the memory location is available. Systems of the present invention provides hardware and/or software based components for implementing the steps of receiving a parameter, determining available memory location, determining if available memory location is pre-assigned, and assigning a packet a parameter if the memory location is available. |
| FILED | Friday, August 26, 2005 |
| APPL NO | 11/213626 |
| ART UNIT | 2419 — Selective Visual Display Systems |
| CURRENT CPC | Multiplex communications 370/412 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532787 | Hall |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Guidance and Electronics Company, Inc. (Woodland Hills, California) |
| INVENTOR(S) | David B. Hall (La Crescents, California) |
| ABSTRACT | A method and apparatus are provided for real-time correction of a voltage drift of an optical switch. The correction may be made without interrupting an optical data stream of the optical switch. Three voltage states of the optical switch may be monitored continuously to determine whether a voltage drift has occurred. Upon determining that the voltage drift has occurred, a signal processing unit with voltage correction circuitry may apply a voltage to a single port of the optical switch to adjust the three voltages of the optical switch equally to achieve a minimum null signal. The technique may be extended to adjust a voltage drift of multiple optical switches connected in series. |
| FILED | Wednesday, June 27, 2007 |
| APPL NO | 11/823344 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07532863 | Bielas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Michael S. Bielas (Tucson, Arizona); Mathew R. Danner (Tucson, Arizona); Brian T. MacIntosh (Tucson, Arizona) |
| ABSTRACT | A testbed is provided for testing broadband wireless test units. The testbed includes an enclosure and a plurality of I/O connectors accessible externally of the enclosure. Each of the I/O connectors is for being electrically coupled to a respective test unit. A series of connections within the enclosure serve to interconnect the plurality of I/O connectors as respective nodes in a bus-mesh network topology. |
| FILED | Monday, October 25, 2004 |
| APPL NO | 10/972873 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/67.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 12, 2009.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2009/fedinvent-patents-20090512.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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