FedInvent™ Patents

Patent Details for Tuesday, July 21, 2009 

This page was updated on Monday, March 27, 2023 at 01:26 AM GMT

Department of Defense (DOD) 

US 07562501 Nguyen
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Dung T. Nguyen (Fountain Valley, California)
ABSTRACT An apparatus for clamping a module within a structure, e.g. a cold-wall structure, is presented. The apparatus includes a plurality of aligned, movable members defining a plane and having at least one beveled surface in contact with a beveled surface of an adjacent member. Guide wires align the movable members. A guide pin is used to guide the insertion of the apparatus into the structure. A screw mechanism, mounted at one end of the apparatus, engages with a hole in the structure. Rotation of the screw mechanism forces an end of the apparatus into contact with the structure. Continued rotation of the screw mechanism generates a compressive force which induces the movable members to move out of the defined plane in opposite directions relative to adjacent members. Members contact a wall of the structure and the module, thereby clamping the module against the structure.
FILED Wednesday, April 20, 2005
APPL NO 11/110385
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/296
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US 07562519 Harris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Mark M. Harris (Palm Beach Gardens, Florida);  Wesley D. Brown (Jupiter, Florida);  Angel M. Garcia (Jupiter, Florida)
ABSTRACT A small gas turbine engine with a compressor, a combustor, and a turbine located downstream of the combustor. The compressor and turbine are supported on a rotary shaft, and a main bearing is support on the rotary shaft, the main bearing being located in a hot zone of the combustor. The main bearing includes cooling air passages within the races to provide cooling for the bearing. A cooling air is diverted from the compressor and passed through the bearing cooling passages for cooling the bearing, and then the cooling air is directed into the combustor. The cooling air is also passed through a guide nozzle before being passed through the bearing to cool both the guide nozzle and the bearing. A swirl cup injector is sued to deliver the compressed air from the compressor and the cooling air from the bearing into the combustor, the swirl cup injector also acting to draw the cooling air through the bearing.
FILED Saturday, September 03, 2005
APPL NO 11/219617
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/39.80
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US 07562562 Beebe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) David J. Beebe (Monona, Wisconsin);  Dongshin Kim (Champaign, Illinois)
ABSTRACT A method and device is provided for detecting a predetermined material. The device includes a first inner layer having first and second surfaces and a volume responsive to a first predetermined stimuli. A second inner layer has first and second surfaces. An adhesive bonds at least a portion of the first surface of the first inner layer to the first surface of the second inner layer with a bonding force. A change in the volume of the first layer generates an elastic force on the adhesive material. As a result, the first inner layer delaminates from the second inner layer in response to the elastic force overcoming the bonding force.
FILED Tuesday, May 08, 2007
APPL NO 11/745855
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/61.430
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US 07562593 Engelbart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Roger W. Engelbart (St. Louis, Missouri);  Eugene A. Myers (St. Charles, Missouri);  Nancy L. Wood (Clayton, Missouri)
ABSTRACT Apparatus and methods for adjustably supporting probes are disclosed. In one embodiment, a sensor support assembly includes a base member adapted to be positioned proximate to and move along a surface of a material, the base member including a first outwardly projecting engagement member and a second outwardly projecting engagement member spaced apart from the first engagement member, and a support member coupled to the base member and including a boss adapted to engage a probe, wherein the first and second engagement members are adapted to engage the surface and to maintain a stand-off distance between the probe and the surface.
FILED Monday, December 11, 2006
APPL NO 11/609235
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/866.500
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US 07563097 Lavigna et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Techno-Sciences, Inc. (Lanham, Maryland);  The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Christopher Lavigna (Olney, Maryland);  Diann Brei (Milford, Michigan);  Jonathan Luntz (Ann Arbor, Michigan);  Anupam Pathak (Ann Arbor, Michigan)
ABSTRACT In a self-contained actively-controlled stabilization system within a hand-grip, all components are contained within the handgrip, and one generic handgrip can be attached to a variety of devices for a wide range of applications, thereby increasing portability, reducing weight and bulkiness, and decreasing complexity and application dependence. The handgrip includes a sensor, a controller and an actuator which preferably employs at least one shape memory alloy wire. The actuator drives a platform mechanism which may be configured such that the elevation and azimuth degrees of freedom are coupled or uncoupled. Direct, rotational and other platform mechanisms may be used with the invention.
FILED Tuesday, September 06, 2005
APPL NO 11/218583
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Education and demonstration
434/16
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US 07563124 Marshall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Patrick T. Marshall (Tipp City, Ohio);  Michael W. McKinley (Xenia, Ohio);  Charley Brun, Jr. (Xenia, Ohio)
ABSTRACT Harvesting power from low-voltage overhead power transmission lines for recharging batteries for use in battery-operated equipment used in urban and remote geographic locations used by military Special Forces, firefighters and remote rescue teams. An elongated metal head containing a razor attached to electrical wire is thrown over an overhead power line where it cuts through insulated cable, makes contact with the hot line, and establishes an electrical connection in order transfer low voltage power to batteries or equipment.
FILED Wednesday, May 21, 2008
APPL NO 12/154812
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrical connectors
439/389
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US 07563390 Holladay et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jamelyn D. Holladay (Kennewick, Washington);  Yong Wang (Richland, Washington);  Jianli Hu (Kennewick, Washington);  Ya-Huei Chin (Richland, Washington);  Robert A. Dagle (Richland, Washington);  Guanguang Xia (Pasco, Washington);  Eddie G. Baker (Pasco, Washington);  Daniel R. Palo (Kennewick, Washington);  Max R. Phelps (Richland, Washington);  Heon Jung (Suhku, South Korea)
ABSTRACT The present invention provides steam reforming catalyst compositions containing Pd and Zn, and methods of steam reforming alcohols over a catalyst. Surprisingly superior results and properties of the present invention, including low temperature activity and/or low carbon monoxide output, are also described. Methods of making a steam reforming catalyst are also provided.
FILED Monday, March 26, 2007
APPL NO 11/691400
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/373
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US 07563480 Villalobos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Guillermo R. Villalobos (Springfield, Virginia);  Jasbinder S. Sanghera (Ashburn, Virginia);  Shyam Bayya (Ashburn, Virginia);  Ishwar D. Aggarwal (Fairfax Station, Virginia)
ABSTRACT A particle having a magnesium aluminate core and a fluoride salt coating on the core. The particle has been heated in an oxidizing atmosphere to a temperature in the range of about 400° C. to about 750° C. A method of making a particle by mixing a magnesium aluminate core with a solution of a fluoride salt in a solvent to form a slurry and spraying the slurry into a drying column. The slurry enters the column as an aerosol under thermal conditions that avoid boiling the solvent. The thermal conditions in the column evaporate the solvent as the aerosol moves through the column to form a coating of the fluoride salt on the core while substantially avoiding spalling.
FILED Monday, September 18, 2006
APPL NO 11/532572
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/215
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US 07563503 Gell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The University of Connecticut (Storrs, Connecticut);  US Nanocorp, Inc. (Farmington, Connecticut);  Inframat Corporation (Farmington, Connecticut)
INVENTOR(S) Maurice Gell (Newington, Connecticut);  Xinqing Ma (Storrs, Connecticut);  Eric Jordan (Storrs, Connecticut);  Nitin P. Padture (Storrs, Connecticut);  Liangde Xie (Storrs, Connecticut);  Danny Xiao (Willington, Connecticut);  Anthony DeCarmine (Lebanon, Connecticut)
ABSTRACT A thermal spray process comprises injecting precursor solution droplets into the hot zone of the thermal spray flame. Also described are materials resulting from the process.
FILED Monday, January 12, 2004
APPL NO 10/755856
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Stock material or miscellaneous articles
428/304.400
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US 07563519 Thompson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Frinceton University (Princeton, New Jersey);  The University of Southern California (Los Angeles, California)
INVENTOR(S) Mark E. Thompson (Anaheim, California);  Yujian You (Los Angeles, California);  Andrei Shoustikov (Los Angeles, California);  Scott Sibley (Baltimore, Maryland);  Paul E. Burrows (Princeton Junction, New Jersey);  Stephen R. Forrest (Princeton, New Jersey)
ABSTRACT Organic light emitting devices are disclosed which are comprised of a heterostructure for producing electroluminescence wherein the heterostructure is comprised of an emissive layer containing a phosphorescent dopant compound. For example, the phosphorescent dopant compound may be comprised of platinum octaethylporphine (PtOEP), which is a compound having the chemical structure with the formula:
FILED Monday, July 23, 2007
APPL NO 11/880676
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Stock material or miscellaneous articles
428/690
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US 07563533 Haile et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Sossina M. Haile (Altadena, California);  Zongping Shao (Pasadena, California)
ABSTRACT Improved cathode active materials for reduced temperature operation in single and dual chamber solid oxide fuel cells are provided. The cathode active materials comprise perovskites of the general form ABO3, where A is a cation with approximately a +2 charge, and B is a cation with approximately a +4 charge. These perovskite cathode materials exhibit substantially enhanced power generation at operation temperatures less than or equal to 600° C.
FILED Friday, June 04, 2004
APPL NO 10/861828
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/40
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US 07563567 Huang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Curators of the Univeristy of Missouri of Columbia (Columbia, Missouri)
INVENTOR(S) Tim Hui-Ming Huang (Columbia, Missouri);  Huidong Shi (Columbia, Missouri)
ABSTRACT Novel methods are herein provided for high-throughput, dual analysis of DNA methylation and gene expression, and triple analysis of DNA methylation, gene expression and gene-associated histone acetylation in cancer cells using arrayed expressed CpG island sequence tags (ECISTs). ECISTs correspond to genomic DNA fragments comprising GC-rich segments along with promoter and/or exon (e.g., first exon) portions of genes. The GC-rich segments are useful for screening hypermethylated CpG sites in cancer cells, while the corresponding promoter and exon-containing portions are useful for determining corresponding transcript levels and assessing histone acetylation. Also provided are high-throughput methods for either confirming methylation-dependent gene silencing, or identifying therapeutically effective demethylating agents, using the ECIST array panels to identify hypermethylated loci, and measure expression levels thereof after cellular exposure to demethylating agents. Further provided are high-throughput methods for distinguishing between direct (primary) demethylation-dependent gene up-regulation, and indirect (secondary) demethylation-dependent up-regulation within apparent epigenetic cascades.
FILED Monday, April 14, 2003
APPL NO 10/414540
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07563569 Seul et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Michael Seul (Fanwood, New Jersey);  Sukanta Banerjee (Pennington, New Jersey);  Jiacheng Yang (Hillsboro, New Jersey);  Tatiana Vener (Stirling, New Jersey)
ABSTRACT Disclosed are methods of multiplexed analysis of oligonucleotides in a sample, including: methods of probe and target “engineering”, as well as methods of assay signal analysis relating to the modulation of the probe-target affinity constant, K by a variety of factors including the elastic properties of target strands and layers of immobilized (“grafted”) probes; and assay methodologies relating to: the tuning of assay signal intensities including dynamic range compression and on-chip signal amplification; the combination of hybridization-mediated and elongation-mediated detection for the quantitative determination of abundance of messages displaying a high degree of sequence similarity, including, for example, the simultaneous determination of the relative expression levels, and identification of the specific class of, untranslated AU-rich subsequences located near the 3′ terminus of mRNA; and a new method of subtractive differential gene expression analysis which requires only a single color label.
FILED Tuesday, October 26, 2004
APPL NO 10/974036
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07563577 Paul, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) John H. Paul, III (St. Petersburg, Florida);  Erica T. Casper (St. Petersburg, Florida);  Stacey S. Patterson (Tampa, Florida)
ABSTRACT The invention provides polynucleotides and methods for detecting and quantifying RNA viruses, such as enteroviruses and noroviruses. In one aspect, the invention provides amplification primers and labeled molecular beacons for amplification of viral nucleic acid sequences. In another aspect, the invention provides a synthetic RNA internal control. In another aspect, the invention provides a kit for detecting the presence of enterovirus and/or norovirus in a sample.
FILED Friday, March 02, 2007
APPL NO 11/713184
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07563601 Gaur
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Rajesh K. Gaur (Glendora, California)
ABSTRACT The present invention relates to riboswitches that have been engineered to regulate pre-mRNA splicing. In particular, the insertion of a high affinity theophylline binding aptamer into the 3′ splice site region, 5′ splice site region, or branchpoint sequence (BPS) of a pre-mRNA modulates RNA splicing in the presence of theophylline. Accordingly, the aspects of the present invention include, but are not limited to, theophylline-dependent riboswitches which modulate RNA splicing, methods of modulating RNA splicing using theophylline and its corresponding riboswitches, methods of improving/identifying theophylline-dependent riboswitches, methods of treating diseases associated with or caused by abnormal RNA splicing.
FILED Thursday, June 01, 2006
APPL NO 11/446527
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.100
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US 07563613 Dennis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Florida (Gainesville, Florida)
INVENTOR(S) Donn M. Dennis (Gainesville, Florida);  Charles R. Martin (Gainesville, Florida);  Timothy E. Morey (Gainesville, Florida);  Richard E. Partch (Potsdam, New York);  Dinesh O Shah (Gainesville, Florida);  Manoj Varshney (Gainesville, Florida)
ABSTRACT A method of removing a toxic compound comprising contacting the toxic compound with a particle having two regions, the first region containing a detoxifying enzyme and the second region containing a material selected to partition the toxic compound into the second region. The particle may be a nanoparticle.
FILED Monday, August 01, 2005
APPL NO 11/195046
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/262
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US 07563734 Gleason et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Karen K. Gleason (Lexington, Massachusetts);  Tyler Phillip Martin (Quincy, Massachusetts);  Kelvin Chan (Cambridge, Massachusetts)
ABSTRACT One aspect of the present invention is directed to antimicrobial surfaces comprised of hydrocarbon polymers with significant hydrophobic character which also contain an amino group with a pKa greater than or equal to about 8. In certain embodiments initiated chemical vapor deposition (iCVD) is used to coat a surface with an antimicrobial polymer.
FILED Monday, April 11, 2005
APPL NO 11/103360
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Fabric
442/123
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US 07563874 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) James D. Marks (Kensington, California);  Peter Amersdorfer (San Diego, California)
ABSTRACT This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/A) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
FILED Friday, August 01, 2003
APPL NO 10/632706
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.150
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US 07563883 Angov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Evelina Angov (Bethesda, Maryland);  Jeffrey A. Lyon (Silver Spring, Maryland);  Christian Asare Darko (Silver Spring, Maryland);  Joe D. Cohen (Brussels, Belgium)
ABSTRACT In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-142. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-142 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
FILED Tuesday, August 14, 2007
APPL NO 11/889578
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.700
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US 07563889 Chapman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert D. Chapman (Ridgecrest, California);  Thomas J. Groshens (Ridgecrest, California)
ABSTRACT 3,3,7,7-Tetrakis(difluoramino)octahydro-1,5-diazocinium intermediate salts and method for making the salts, through difluoramination followed by N-denosylation or N-deprotection, which are valuable for use as precursor(s) to HNFX as well as to other members of the rare class of 3,3,7,7-tetrakis(difluoramino)octahydro-1,5-diazocines.
FILED Friday, December 10, 2004
APPL NO 11/010058
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
540/470
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US 07563891 Pitner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) Becton, Dickinson and Company (Franklin Lakes, New Jersey)
INVENTOR(S) J. Bruce Pitner (Durham, North Carolina);  Douglas B. Sherman (Durham, North Carolina);  Arounaguiry Ambroise (Morrisville, North Carolina);  Joseph Thomas (Raleigh, North Carolina)
ABSTRACT Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus.
FILED Wednesday, May 18, 2005
APPL NO 11/131283
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
544/105
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US 07564152 Clark et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Arthur E. Clark (Adelphi, Maryland);  James B. Restorff (College Park, Maryland);  Marilyn Wun-Fogle (Potomac, Maryland)
ABSTRACT An elongate structure having a magnetostrictive material composition is subjected to tensile stress in the longitudinal-axial direction, thereby generally orienting the magnetization of the elongate structure in the longitudinal-axial direction. Electrical current is conducted through the elongate structure and/or through at least one adjacent elongate conductor, thereby generally orienting the magnetization of the elongate structure in the transverse direction, generally in parallel with the transverse direction of the magnetic field concomitant the conduction of current through the elongate structure. The elongate structure magnetostrictively contracts due to the (generally 90°) repositioning of the magnetization of the elongate structure. Examples of inventive configurational variants include: (i) an elongate structure itself conducting current; (ii) a hollow elongate structure accommodating placement therethrough of at least one elongate conductor; (iii) an elongate structure flanked by a pair of elongate conductors conducting current in opposite directions; (iv) plural elongate structures bordering a centralized elongate conductor.
FILED Monday, January 31, 2005
APPL NO 11/053753
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrical generator or motor structure
310/26
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US 07564455 Gatewood, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Walter P. Gatewood, Jr. (Lexington Park, Maryland);  Ingi A. Ford (Great Mills, Maryland);  Bryan M. Vandrovec (Great Mills, Maryland);  Donald G. Mielcarek (Lexington Park, Maryland);  David A. Kirkpatrick (Solomons, Maryland)
ABSTRACT A system and process that incorporates hardware and software as elements to be combined with procedures and processes to obtain, format, store, combine, control, display, record, and visualize dynamic scenarios by interacting with accurate, realistic models and actual events within, on, and above a three-dimensional surface to be observed or modeled. The present invention software and process is capable of displaying extremely high resolution terrain models and imagery in real time over the entire surface of the planet, as well as a large number of moving entities and their associated graphical models. These features, combined with a network application programming interface (API), make the present invention suitable for flight simulation out-the-window displays, command and control scenarios, and mission review or rehearsal.
FILED Tuesday, December 06, 2005
APPL NO 11/296723
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/419
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564567 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jerry C. Chen (Lexington, Massachusetts);  Sumanth Kaushik (Belmont, Massachusetts)
ABSTRACT Described are a sensor and a method for measuring a vibration of a surface obscured from view. The sensor includes a narrowband source of a terahertz beam, a beamsplitter, a beam combiner and a terahertz detector. The beamsplitter splits the terahertz beam into a sample beam for irradiating the surface and a reference beam. The beam combiner combines the sample beam scattered from the surface and the reference beam. The terahertz detector generates an electrical signal based on a modulation of the power of the combined beams due to the vibrating surface. The electrical signal indicates a characteristic of the surface vibration. Homodyne or heterodyne detection can be utilized. Advantageously, the sensor can see surfaces that are covered, concealed or otherwise obscured behind optically opaque materials, including plastic, cloth, foam, paper and other materials. Thus the sensor has a wide variety of applications where conventional vibrometers are not practical.
FILED Thursday, January 25, 2007
APPL NO 11/626966
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/502
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564739 Ehrenreich et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Sebastian Ehrenreich (Schoenau, Germany);  Jente B Kuang (Austin, Texas);  Chun-Tao Li (Rochester, Minnesota);  Hung Kai Ngo (Austin, Texas)
ABSTRACT A storage cell design evaluation circuit including a wordline timing and cell access detection circuit provides accurate information about state changes in static storage cells. A storage cell test row includes the access detection circuit, which provides the same loading during an access operation as the other cells in the array. The access detection circuit provides an output that may be probed without affecting the timing, read stability or writeability of the cell. The test row can test the clock and/or address timing of the row and may include a separate power supply rail for the row wordline driver, so that variation of access timing, read stability and writeability with wordline strength/access voltage can be determined. Multiple test rows may be cascaded among columns to provide a long delay line or ring oscillator for improved measurement resolution.
FILED Wednesday, May 21, 2008
APPL NO 12/125011
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/239
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564809 Manohar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Rajit Manohar (Ithaca, New York);  Clint Kelly (Ithaca, New York)
ABSTRACT An event synchronization protocol called time-based synchronization (TBS) is employed to control operation of a network simulation. In TBS, processors in the simulated network execute events based on comparisons between timestamps for each event and a value generated by a time tracking device in the processor. In this manner, event execution is not dependent on other processes in the network and the simulation can actually be carried out at speeds faster than real time. A multiprocessor network is specially designed to execute TBS-based simulations.
FILED Friday, May 06, 2005
APPL NO 11/123233
ART UNIT 2416 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/310
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564816 McHenry et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Shared Spectrum Company (Vienna, Virginia)
INVENTOR(S) Mark Allen McHenry (McLean, Virginia);  Alexe E. Leu (Arlington, Virginia)
ABSTRACT A method and transceiver for determining spectrum availability within a give area is disclosed. The given area includes cells in a grid. A belief evaluator receives a measurement from a signal and assigns an instantaneous belief indicator, an instantaneous disbelief indicator and an instantaneous ignorance indicator based on a detection threshold and the power level of the measurement. The indicators quantify the probability of a presence of a transmitter within the grid cell. A belief accumulator uses the instantaneous indicators along with accumulated belief, disbelief and ignorance indicators from previous measurements to determine cumulative belief, disbelief and ignorance indicators. The accumulated belief, disbelief and ignorance indicators are the results of previous measurements and belief/disbelief/ignorance determinations for the grid cell. An allocator indicates the status of the grid cell and whether a spectrum is available. If a spectrum is available, then the grid cell is added to other available cells within the area to generate the spectrum hole.
FILED Friday, May 12, 2006
APPL NO 11/432536
ART UNIT 2617 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/329
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564920 Dally
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William J. Dally (Stanford, California)
ABSTRACT An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to emphasize transition signal levels relative to repeated signal levels. The preferred equalizer includes an FIR transition filter using a look-up table. Parallel circuits including FIR filters and digital-to-analog converters provide a high speed equalizer with lower speed circuitry. The equalizer is particularly suited to in-cabinet and local area network transmissions where feedback circuitry facilitates adaptive training of the equalizer.
FILED Thursday, August 31, 2006
APPL NO 11/514515
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/296
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565046 Feng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ning-Ning Feng (Somerville, Massachusetts);  Rong Sun (Cambridge, Massachusetts);  Lionel C. Kimerling (Concord, Massachusetts);  Jurgen Michel (Arlington, Massachusetts)
ABSTRACT The mode transforming structure includes a first waveguide structure. A slot waveguide region is coupled to the first waveguide structure. The slot waveguide region includes one or more complementary tapered pairs so near lossless transforming between the first waveguide structure and the slot waveguide region occurs so as to allow optical modes to be transferred between the first waveguide and the slot waveguide region.
FILED Wednesday, December 12, 2007
APPL NO 11/954461
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/28
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565340 Herlocker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Science Foundation (NSF)
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) The State of Oregon Acting by and through the State Board of Higher Education on Behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Jonathan L. Herlocker (Philomath, Oregon);  Thomas G. Dietterich (Corvallis, Oregon)
ABSTRACT A method for assisting multi-tasking computer users includes receiving from a user a specification of a task being performed by the user or an indication of completion of a task, collecting state changes in multiple executing programs, predicting a current task being performed by the user based on a recent state change event, a past specification of a task being performed by the user, and past events and associated tasks. Based on the predicted current task, user interface elements in multiple executing programs are adapted to facilitate performance of the task. The method may also allow a user to specify a new task based on a task template derived from a completed task to facilitate completion of the new task. The task templates also may be shared among users, and active tasks may also be team tasks shared among users.
FILED Tuesday, May 30, 2006
APPL NO 11/443503
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/52
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565392 Turner
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Steven Turner (Westbrook, Maine)
ABSTRACT A carry/majority circuit, comprising a plurality of differential transistor pairs coupled in parallel and forming a pair of output nodes, with a single parallel gated level. Current is steered through a leg of the transistor pair having a higher input voltage.
FILED Wednesday, July 06, 2005
APPL NO 10/593807
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers: Arithmetic processing and calculating
78/701
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565540 Bogasky et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Accenture Global Services GmbH (Schaffhausen, Switzerland)
INVENTOR(S) John J. Bogasky (Silver Spring, Maryland);  Carl Almond (Tampa, Florida);  Andrew Schaefer (Hoboken, New Jersey)
ABSTRACT The present invention relates to a system and method for fully electronic identity authentication, with particular application to electronic election registration and voting. In particular, the present invention provides an authentication system that operates in conjunction with a secure server to authenticate users to provide access information as needed for the authenticated users to access the secure server.
FILED Friday, July 08, 2005
APPL NO 11/176681
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Support
713/173
VIEW PATENT @ USPTO:  Full Text   PDF 
US D596762 Ruegsegger
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
APPLICANT(S)
ASSIGNEE(S) APG West, Inc. (Phoenix, Arizona)
INVENTOR(S) Jack Ruegsegger (Glendale, Arizona)
ABSTRACT
FILED Thursday, October 11, 2007
APPL NO 29/292510
ART UNIT 2914 — Design
CURRENT CPC
Building units and construction elements
D25/113
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07563446 Schroit
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Alan J. Schroit (Houston, Texas)
ABSTRACT Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal. Also disclosed are methods for making phosphatidylserine conjugate compositions and their formulation for use in a variety of pharmaceutical applications including the detection and treatment of a variety of cancers and related conditions.
FILED Tuesday, August 31, 2004
APPL NO 10/930686
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563447 Franzusoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) GlobeImmune, Inc. (Louisville, Colorado)
INVENTOR(S) Alex Franzusoff (Denver, Colorado);  Donald Bellgrau (Highlands Ranch, Colorado)
ABSTRACT Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.
FILED Monday, June 25, 2007
APPL NO 11/768144
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/191.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563448 Ellenhorn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Joshua D.I. Ellenhorn (Beverly Hills, California);  Don J. Diamond (Glendora, California)
ABSTRACT Mutations to the tumor suppressor protein p53 have been observed in 40-60% of all human cancers. These mutations are often associated with high nuclear and cytoplasmic concentrations of p53. Since many tumors exhibit highly elevated p53 levels, the protein is an attractive target for cancer immunotherapy. Unfortunately, p53 is an autoantigen that is likely to be tolerated as a self-protein by the immune system. The present invention is based on the discovery that this self-tolerance can be overcome by administration of recombinant modified vaccinia Ankara (MVA) containing a nucleic acid that encodes p53 (rMVAp53). The invention discloses a method of generating a p53-specific CTL response to tumor cells expressing mutated p53 by administering a composition comprising rMVAp53. Administration of rMVAp53 decreases tumor development, tumor growth, and mortality in a variety of malignant cell types. These effects are enhanced by administration of CTLA-4 blocker and/or CpG oligodeoxynucleotide immunomodulators.
FILED Monday, May 21, 2007
APPL NO 11/805180
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/199.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563567 Huang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Curators of the Univeristy of Missouri of Columbia (Columbia, Missouri)
INVENTOR(S) Tim Hui-Ming Huang (Columbia, Missouri);  Huidong Shi (Columbia, Missouri)
ABSTRACT Novel methods are herein provided for high-throughput, dual analysis of DNA methylation and gene expression, and triple analysis of DNA methylation, gene expression and gene-associated histone acetylation in cancer cells using arrayed expressed CpG island sequence tags (ECISTs). ECISTs correspond to genomic DNA fragments comprising GC-rich segments along with promoter and/or exon (e.g., first exon) portions of genes. The GC-rich segments are useful for screening hypermethylated CpG sites in cancer cells, while the corresponding promoter and exon-containing portions are useful for determining corresponding transcript levels and assessing histone acetylation. Also provided are high-throughput methods for either confirming methylation-dependent gene silencing, or identifying therapeutically effective demethylating agents, using the ECIST array panels to identify hypermethylated loci, and measure expression levels thereof after cellular exposure to demethylating agents. Further provided are high-throughput methods for distinguishing between direct (primary) demethylation-dependent gene up-regulation, and indirect (secondary) demethylation-dependent up-regulation within apparent epigenetic cascades.
FILED Monday, April 14, 2003
APPL NO 10/414540
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563573 Fornace, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Albert J. Fornace, Jr. (Bethesda, Maryland);  Sally A. Amundson (Rockville, Maryland);  Jeffrey M. Trent (Rockville, Maryland)
ABSTRACT A method is disclosed for detecting exposure of organisms to biologically significant or hazardous amounts of ionizing radiation. The method uses nucleic acid microarray hybridization to evaluate biological effects, such as patterns of expression of genes after radiation exposure. Numerous genes are provided which have been found to be responsive to radiation exposure in a variety of cell lines. These genes are incorporated into probe sets, which are exposed to a labeled nucleic acid composition from a test cell, such as cDNA reverse transcribed from mRNA in the test cell, which specifically hybridizes to members of the probe set when the cell has been exposed to a biologically significant amount of ionizing radiation. Whether the nucleic acid composition hybridizes to the nucleic acid molecules representing genes that are differentially expressed is determined. The invention also includes methods for determining a dose response relationship between radiation exposure and differential expression of one or more genes, for example to determine a probable radiation dose in cells that have actually or potentially been exposed to the ionizing radiation. The invention also includes probe sets and microarrays used in this method.
FILED Monday, March 06, 2006
APPL NO 11/370079
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563583 Ballinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Genentech, Inc. (South San Francisco, California)
INVENTOR(S) Marcus D Ballinger (Burlingame, California);  Jennifer T Jones (San Leandro, California);  Wayne J Fairbrother (Burlingame, California);  Mark S Sliwkowski (San Carlos, California);  James A Wells (South San Francisco, California)
ABSTRACT The present invention provides heregulin variants that are capable of binding an ErbB receptor. Included in the invention are variants of human heregulins, and, in particular, variants of human heregulin-β1 having enhanced affinity for the ErbB-3 and ErbB-4 receptors. These variants include at least one amino acid substitution and can include further modifications. The invention also provides nucleic acid molecules encoding heregulin variants and related vectors, host cells, pharmaceutical compositions, and methods.
FILED Thursday, February 02, 2006
APPL NO 11/347808
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563584 Perez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Omar D. Perez (Stanford, California);  Garry P. Nolan (San Francisco, California)
ABSTRACT The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides methods and compositions of screening for bioactive agents capable of coordinately modulating the activity of a plurality of proteins in single cells. The methods and compositions can be used to determine the protein activation profile of a cell for predicting or diagnosing a disease state, and for monitoring treatment of a disease state.
FILED Wednesday, July 10, 2002
APPL NO 10/193462
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563589 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Yi Zhang (Chapel Hill, North Carolina);  Ru Cao (Chapel Hill, North Carolina)
ABSTRACT The present invention provides a reconstituted complex including EED, EZH2 and SUZ12 wherein the reconstituted complex has histone methyltransferase (HMTase) activity for lysine 27 of histone H3 (H3-K27). The reconstituted complex may further include RbAp48, AEBP2 or both. Also disclosed are methods of producing the reconstituted complex, methods of identifying compounds that inhibit the HTMase activity of the reconstituted complex and methods of identifying candidate compounds for treating cancer. Reagents and kits including the reconstituted complex are further provided.
FILED Friday, May 27, 2005
APPL NO 11/140659
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/15
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563595 Cuevas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Javier Cuevas (Lutz, Florida);  Emily Severance (Lutz, Florida)
ABSTRACT The present invention concerns a novel α7 nicotinic receptor subunit isoform, α7-2. The α7-2 isoform contributes to novel acetylcholine receptors (AChRs) with pharmacological and biophysical properties distinct from those of wild-type α7-1-nAChRs and closely resembling those of α7-nAChRs found in intrinsic cardiac neurons and Type II α7-nAChRs of superior cervical ganglion neurons. Polynucleotides encoding the α7-2 isoform, vectors and genetically modified cells containing such polynucleotides are also provided. In addition, methods are provided for producing the α7-2 isoform as are methods of using such isoforms for screening compounds for activity at the nAChR.
FILED Friday, November 07, 2003
APPL NO 10/703953
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563596 Luyten et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Frank P. Luyten (Rockville, Maryland);  Malcolm Moos, Jr. (Bethesda, Maryland);  Bang Hoang (University Heights, Ohio);  Shouwen Wang (Rockville, Maryland)
ABSTRACT An isolated cDNA encoding a growth-inducing protein, Frzb, capable of stimulating bone, cartilage, muscle and nerve tissue formation. Frzb binds to and modulates the activity of Wnt growth factors which play a role in various developmental and neoplastic processes. The cDNA and protein sequences of human, bovine and Xenopus Frzb are provided. Production and purification of recombinant Frzb are also described.
FILED Monday, July 18, 2005
APPL NO 11/184005
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563597 Ahlquist et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Paul G. Ahlquist (Madison, Wisconsin);  Dohun Pyeon (Madison, Wisconsin);  Paul F. Lambert (Madison, Wisconsin)
ABSTRACT A method of producing a packaged DNA sequence is disclosed. In one embodiment, the method comprises the steps of: (a) selecting a DNA sequence to be packaged and a papillomaviral capsid sequence, wherein the DNA sequence to be packaged is between 7 Kb-8.5 Kb, (b) co-transfecting the products of step (a) into transfectable cells, wherein the DNA sequence is packaged, and (c) purifying packaged particles.
FILED Monday, January 30, 2006
APPL NO 11/275819
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563601 Gaur
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Rajesh K. Gaur (Glendora, California)
ABSTRACT The present invention relates to riboswitches that have been engineered to regulate pre-mRNA splicing. In particular, the insertion of a high affinity theophylline binding aptamer into the 3′ splice site region, 5′ splice site region, or branchpoint sequence (BPS) of a pre-mRNA modulates RNA splicing in the presence of theophylline. Accordingly, the aspects of the present invention include, but are not limited to, theophylline-dependent riboswitches which modulate RNA splicing, methods of modulating RNA splicing using theophylline and its corresponding riboswitches, methods of improving/identifying theophylline-dependent riboswitches, methods of treating diseases associated with or caused by abnormal RNA splicing.
FILED Thursday, June 01, 2006
APPL NO 11/446527
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563612 Saxena et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Brij B. Saxena (Englewood, New Jersey);  Premila Rathnam (Englewood Cliffs, New Jersey);  Makul Singh (Teaneck, New Jersey);  Meirong Hao (Rego Park, New York)
ABSTRACT The present invention relates to a chimeric nucleic acid molecule encoding a fusion protein having a human lutropin hormone-receptor domain and a human chorionic gonadotropin-β subunit domain, the isolated human lutropin hormone-receptor/human chorionic gonadotropin-β fusion protein, and antibodies which recognize part or all the domains of the fusion protein. Also provided are compositions having the human lutropin hormone-receptor/human chorionic gonadotropin-β fusion protein and a pharmaceutical carrier and compositions including antibodies to the fusion protein and a pharmaceutical carrier. The present invention also relates to methods of treating androgen-excess-mediated disease conditions by administering to a subject an antibody to the human lutropin hormone-receptor/human chorionic gonadotropin-β fusion protein under conditions suitable to treat the conditions, and methods of immunocontraception that involve administering to a subject the chimeric nucleic acid molecule encoding the human lutropin hormone receptor/human chorionic gonadotropin-β fusion protein, the fusion protein in whole or in part, or antibodies thereto.
FILED Monday, September 26, 2005
APPL NO 11/235621
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563613 Dennis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Florida (Gainesville, Florida)
INVENTOR(S) Donn M. Dennis (Gainesville, Florida);  Charles R. Martin (Gainesville, Florida);  Timothy E. Morey (Gainesville, Florida);  Richard E. Partch (Potsdam, New York);  Dinesh O Shah (Gainesville, Florida);  Manoj Varshney (Gainesville, Florida)
ABSTRACT A method of removing a toxic compound comprising contacting the toxic compound with a particle having two regions, the first region containing a detoxifying enzyme and the second region containing a material selected to partition the toxic compound into the second region. The particle may be a nanoparticle.
FILED Monday, August 01, 2005
APPL NO 11/195046
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/262
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563617 Hearing et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation Of State University of New York (Albany, New York)
INVENTOR(S) Patrick Hearing (St. James, New York);  Wadie F. Bahou (Setauket, New York);  Ziv Sandalon (Bellevue, Washington);  Dmitri V. Gnatenko (Port Jefferson, New York)
ABSTRACT The invention provides recombinant vectors including adenovirus/adeno-associated virus (Ad/AAV) vectors and mini-adenovirus (mAd) vectors. Further, the invention provides cells containing these vectors, and methods for making and using the vectors and cells. The compositions and methods of the invention are useful in transferring nucleotide sequences of interest into a cell, including, but not limited to, in gene therapy applications.
FILED Thursday, May 12, 2005
APPL NO 11/127832
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563619 Williams et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Van Andel Research Institute (Grand Rapids, Michigan);  Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Bart Williams (Grand Rapids, Michigan);  Caroline M. Alexander (Madison, Wisconsin);  Charlotta Lindvall (Grand Rapids, Michigan);  Nisha McConnell (Madison, Wisconsin)
ABSTRACT It is disclosed here that low density lipoprotein receptor-related protein 5 (LRP5) is a cell surface marker for somatic mammary stem cells and mammary tumor stem cells. The disclosure here provides new tools for enriching somatic mammary stem cells and mammary tumor stem cells. Methods of screening for agents that modulate LRP5 activity, of treating mammary tumor or breast cancer, of monitoring somatic mammary stem cells and mammary tumor stem cells in vivo are also provided, and of assessing prognosis of human breast cancer.
FILED Wednesday, May 30, 2007
APPL NO 11/807937
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563766 Philp et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Deborah Philp (Rockville, Maryland);  Hynda K. Kleinman (Kensington, Maryland);  Michael Elkin (Jerusalem, Israel)
ABSTRACT Disclosed herein are methods and compositions suitable for the promotion of hair growth on humans and other animals. Disclosed embodiments include compositions comprising actin-binding peptides. In some embodiments, the actin-binding peptides comprise fragments of thymosin β4. In other embodiments, the disclosure provides compositions comprising fragments of thymosin β4 and/or other actin-binding peptides that are suitable for the treatment of alopecia and other conditions associated with hair loss. In still further embodiments, the disclosure provides compositions comprising the sequence of approximately six or seven amino acids of the thymosin β4 sequence that bind actin.
FILED Wednesday, January 22, 2003
APPL NO 10/502115
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563772 Mochly-Rosen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Daria Mochly-Rosen (Menlo Park, California);  Rachel Bright (Claremont, California)
ABSTRACT Methods of increasing blood flow in a mammalian brain blood vessel characterized by, or otherwise experiencing, decreased blood flow due to an ischemic or other hypoxic event, vasoconstriction or vasospasm following hemorrhagic stroke; due to chronic high blood pressure; and/or due to idiopathic causes are provided. The method for increasing blood flow in such a mammalian brain blood vessel includes administering to a patient in need thereof a therapeutically effective amount of an inhibitor of δ protein kinase C. In certain embodiments, the inhibitor can be chronically administered without causing desensitization of the patient to the inhibitor. Kits for increasing blood flow in a mammalian brain blood vessel characterized by, or otherwise experiencing, decreased blood flow due to an ischemic or other hypoxic event, vasoconstriction or vasospasm following hemorrhagic stroke; due to chronic high blood pressure; and/or due to idiopathic causes are provided.
FILED Friday, December 23, 2005
APPL NO 11/317806
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/16
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563775 Villafuerte
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Betty C. Villafuerte (Lousiville, Kentucky)
INVENTOR(S) Betty C. Villafuerte (Louisville, Kentucky)
ABSTRACT The present invention relates to the novel protein Insulin-Responsive DNA Binding Protein-1 (IRDBP-1) and nucleotide sequences that encode it. IRDBP-1 binds to nucleic acid regions of genes that respond when cells are exposed to insulin. IRDBP-1 regulates genes important in mediating the insulin response in mammals and in regulating conditions such as diabetes, obesity, insulin-resistant syndrome and cell proliferative disorders. The present invention provides nucleic acids useful as probes for detecting nucleic acids encoding regions of the IRDBP-1 protein. Within the scope of the present invention are recombinant cells, tissues and animals containing non-naturally occurring recombinant nucleic acid molecules encoding IRDBP-1, including expression vectors, antibodies specific for IRDBP-1, assays for IRDBP-1 polypeptide, and methods relating to all of the foregoing, the development of therapeutic and diagnostic agents that mimic, facilitate or inhibit the action of IRDBP-1, and/or are based on relationships to the structure and action of IRDBP-1.
FILED Wednesday, December 04, 2002
APPL NO 10/310002
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563868 Yajnik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Vandana Yajnik (Brookline, Massachusetts);  Herbert H. Samuels (New Rochelle, New York);  Dangsheng Li (New York, New York)
ABSTRACT Nucleic acids encoding NRIF3 are described. Polypeptides having amino acid sequences of NRIF3 proteins are also provided. A method is also provided for isolating and cloning NRIF3 cDNA. NRIF3 is useful in development/implementation of high throughput screens to identify novel thyroid hormone receptor (TR) and retinoid X receptor (RXR) agonists and antagonists. Methods are also provided for identifying compounds that directly interfere with the interaction of NRIF3 and TR or RXR. Finally, therapies based on modulation of NRIF3 activity are disclosed.
FILED Monday, May 19, 2003
APPL NO 10/441967
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564618 Shribak
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Mykhailo Shribak (Woods Hole, Massachusetts)
ABSTRACT A method for performing differential interference contrast microscopy on a specimen includes collecting at least two images with illumination respectively having first and second beam-shear directions relative to a rotational orientation of the specimen, determining data associated with an intensity distribution of each of the collected images, and calculating values having a spatial distribution that is substantially independent of the rotational orientation of the specimen. A differential interference contrast microscope includes a beam-shearing assembly that includes a beam-shearing component. The beam-shearing assembly is configured to provide a variable shear vector without a movement of the beam-shearing component. A microscopy system can include the microscope and an imaging-control unit.
FILED Monday, June 18, 2007
APPL NO 11/820219
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/371
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564980 Zurek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) Sensimetrics Corporation (Somerville, Massachusetts)
INVENTOR(S) Patrick M. Zurek (Arlington, Massachusetts);  Joseph G. Desloge (Brookline, Massachusetts)
ABSTRACT An immersive hearing loss and auditory prostheses simulator allows a person who listens through the simulation system to experience an actual shift in his or her thresholds for detecting ambient sounds, in a way that is similar to the shift in thresholds experienced by a hearing-impaired person. The simulator shifts the listener's thresholds while also processing the input signals for suprathreshold stimulation. With a controlled degree of auditory threshold shift with loudness recruitment, a hearing loss simulator is made valid and flexible.
FILED Thursday, April 21, 2005
APPL NO 11/111036
ART UNIT 2614 — Optics
CURRENT CPC
Electrical audio signal processing systems and devices
381/60
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565198 Bennett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S) Medtronic Urinary Solutions, Inc. (Minneapolis, Minnesota)
INVENTOR(S) Maria Bennett (Lyndhurst, Ohio);  Robert B. Strother (Willoughby Hills, Ohio);  Julie Grill (Chapel Hill, North Carolina);  Joseph J. Mrva (Euclid, Ohio);  Therese Zmina (Willoughby, Ohio);  Geoffrey B. Thrope (Shaker Heights, Ohio)
ABSTRACT Systems and methods treat urinary incontinence by the bilateral stimulation of the left and/or right branches of the dorsal genital nerves using a single lead implanted in adipose or other tissue in the region at or near the pubic symphysis.
FILED Friday, June 10, 2005
APPL NO 11/149654
ART UNIT 3766 — Optics
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565202 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert J. Greenberg (Los Angeles, California);  Richard Williamson (Saugus, California)
ABSTRACT The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
FILED Friday, January 31, 2003
APPL NO 10/355793
ART UNIT 3766 — Optics
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565340 Herlocker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Science Foundation (NSF)
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) The State of Oregon Acting by and through the State Board of Higher Education on Behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Jonathan L. Herlocker (Philomath, Oregon);  Thomas G. Dietterich (Corvallis, Oregon)
ABSTRACT A method for assisting multi-tasking computer users includes receiving from a user a specification of a task being performed by the user or an indication of completion of a task, collecting state changes in multiple executing programs, predicting a current task being performed by the user based on a recent state change event, a past specification of a task being performed by the user, and past events and associated tasks. Based on the predicted current task, user interface elements in multiple executing programs are adapted to facilitate performance of the task. The method may also allow a user to specify a new task based on a task template derived from a completed task to facilitate completion of the new task. The task templates also may be shared among users, and active tasks may also be team tasks shared among users.
FILED Tuesday, May 30, 2006
APPL NO 11/443503
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/52
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565540 Bogasky et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Accenture Global Services GmbH (Schaffhausen, Switzerland)
INVENTOR(S) John J. Bogasky (Silver Spring, Maryland);  Carl Almond (Tampa, Florida);  Andrew Schaefer (Hoboken, New Jersey)
ABSTRACT The present invention relates to a system and method for fully electronic identity authentication, with particular application to electronic election registration and voting. In particular, the present invention provides an authentication system that operates in conjunction with a secure server to authenticate users to provide access information as needed for the authenticated users to access the secure server.
FILED Friday, July 08, 2005
APPL NO 11/176681
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Support
713/173
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE40862 Flack et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Mary R. Flack (Ann Arbor, Michigan);  Richard Knazek (Mount Airy, Maryland);  Marcus Reidenberg (Scarsdale, New York)
ABSTRACT A method for treating cancer in a human, which comprises administering to the human subject an anti-cancer effective amount of a compound selected from gossypol, gossypol acetic acid, gossypolone, metabolites thereof, or physiologically acceptable salts thereof. Also included is a method for treating cancer in a human which comprises administering to the human subject an anti-cancer effective amount of any of the compounds listed above in combination with an anti-cancer effective amount of other conventional chemotherapeutic agents. Finally, the invention also encompasses a pharmaceutical composition comprising an anti-cancer effective amount of gossypol, gossypol acetic acid, or gossypolone, and an anti-cancer effective amount of a conventional chemotherapeutic agent, or combinations of the latter.
FILED Monday, October 16, 2006
APPL NO 11/581734
ART UNIT 1614 — Design
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/682
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07562588 Absmeier et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Delphi Technologies, Inc. (Troy, Michigan)
INVENTOR(S) John P. Absmeier (Rochester, New York);  Sean M. Kelly (Pittsford, New York);  Gail E. Geiger (Caledonia, New York)
ABSTRACT In an SOFC stack system, a reformer supplies reformate to the stack. An anode tail gas portion is recycled into the reformer. An inline flowmeter indicates an apparent recycle flow rate. A map of anode tail gas composition as a function of fuel utilization efficiency U, reformer oxygen/carbon ratio O:C, and recycle percentage R is generated on a laboratory test bed at various recycle rates and fuel utilization rates. Compositions are sent through a flowmeter and a Coriolus mass flowmeter provide a Coriolus flow and sensor voltage function across the various compositions and flow rates to create an average curve and an average (reference) voltage at a given flow. A scale factor Z is calculated and used to determine a scaled sensor voltage X for use in an average flow polynomial curve fit equation to calculate tail gas mass flow rate at any flow value indicated by the flow meter.
FILED Thursday, April 27, 2006
APPL NO 11/412620
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/861.850
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07562706 Li et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Shell Oil Company (Houston, Texas)
INVENTOR(S) Ruijian Li (Katy, Texas);  John Michael Karanikas (Houston, Texas)
ABSTRACT A system for treating a tar sands formation is disclosed. A plurality of heaters are located in the formation. The heaters include at least partially horizontal heating sections at least partially in a hydrocarbon layer of the formation. The heating sections are at least partially arranged in a pattern in the hydrocarbon layer. The heaters are configured to provide heat to the hydrocarbon layer. The provided heat creates a plurality of drainage paths for mobilized fluids. At least two of the drainage paths converge. A production well is located to collect and produce mobilized fluids from at least one of the converged drainage paths in the hydrocarbon layer.
FILED Friday, October 20, 2006
APPL NO 11/584429
ART UNIT 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Wells
166/245
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07562707 Miller
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Shell Oil Company (Houston, Texas)
INVENTOR(S) David Scott Miller (Katy, Texas)
ABSTRACT Method for treating a hydrocarbon containing formation are described herein. Methods may include providing heat to a first section of the formation with one or more first heaters in the first section. First hydrocarbons may be heated in the first section such that at least some of the first hydrocarbons are mobilized. At least some of the mobilized first hydrocarbons may be produced through a production well located in a second section of the formation. The second section may be located substantially adjacent to the first section. A portion of the second section may be provided some heat from the mobilized first hydrocarbons, but is not conductively heated by heat from the first heaters. Heat may be provided to the second section with one or more second heaters in the second section to further heat the second section.
FILED Friday, October 19, 2007
APPL NO 11/975688
ART UNIT 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Wells
166/245
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07562878 Dietle et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Kalsi Engineering, Inc. (Sugar Land, Texas)
INVENTOR(S) Lannie L. Dietle (Houston, Texas);  John E. Schroeder (Richmond, Texas)
ABSTRACT A hydrodynamically lubricating geometry for the generally circular dynamic sealing lip of rotary seals that are employed to partition a lubricant from an environment. The dynamic sealing lip is provided for establishing compressed sealing engagement with a relatively rotatable surface, and for wedging a film of lubricating fluid into the interface between the dynamic sealing lip and the relatively rotatable surface in response to relative rotation that may occur in the clockwise or the counter-clockwise direction. A wave form incorporating an elongated dimple provides the gradual convergence, efficient impingement angle, and gradual interfacial contact pressure rise that are conducive to efficient hydrodynamic wedging. Skewed elevated contact pressure zones produced by compression edge effects provide for controlled lubricant movement within the dynamic sealing interface between the seal and the relatively rotatable surface, producing enhanced lubrication and low running torque.
FILED Wednesday, March 22, 2006
APPL NO 11/386209
ART UNIT 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Seal for a joint or juncture
277/559
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563292 Ahmed et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Shabbir Ahmed (Naperville, Illinois);  Sheldon H. D. Lee (Willowbrook, Illinois);  John David Carter (Bolingbrook, Illinois);  Michael Krumpelt (Naperville, Illinois);  Deborah J. Myers (Lisle, Illinois)
ABSTRACT A method of producing a H2 rich gas stream includes supplying an O2 rich gas, steam, and fuel to an inner reforming zone of a fuel processor that includes a partial oxidation catalyst and a steam reforming catalyst or a combined partial oxidation and stream reforming catalyst. The method also includes contacting the O2 rich gas, steam, and fuel with the partial oxidation catalyst and the steam reforming catalyst or the combined partial oxidation and stream reforming catalyst in the inner reforming zone to generate a hot reformate stream. The method still further includes cooling the hot reformate stream in a cooling zone to produce a cooled reformate stream. Additionally, the method includes removing sulfur-containing compounds from the cooled reformate stream by contacting the cooled reformate stream with a sulfur removal agent. The method still further includes contacting the cooled reformate stream with a catalyst that converts water and carbon monoxide to carbon dioxide and H2 in a water-gas-shift zone to produce a final reformate stream in the fuel processor.
FILED Friday, February 27, 2004
APPL NO 10/789219
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Gas: Heating and illuminating
048/61
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563484 Wang et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Hsing-Lin Wang (Los Alamos, New Mexico);  Benjamin R. Mattes (Santa Fe, New Mexico)
ABSTRACT Immersion precipitation of solutions having 15%-30% (w/w) and various molecular weights of the emeraldine base form of polyaniline in polar aprotic solvents are shown to form integrally skinned asymmetric membranes and fibers having skin layers <1 μm thick which exhibit improved rates of gas transport while preserving good selectivity. These membranes can be further transformed by an acid doping process after fabrication to achieve excellent permeation rates and high selectivities for particular gas separations. Prior to the use of concentrated EB solutions, the formation of integrally skinned asymmetric membranes was not possible, since films and fibers made from <5% w/w polyaniline solutions were found to disintegrate during the IP process.
FILED Tuesday, September 28, 2004
APPL NO 10/953673
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/387
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563532 Choudhury et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) E.I. du Pont de Nemours and Company (Wilmington, Delaware)
INVENTOR(S) Biswajit Choudhury (Kingston, Canada);  Mark Gerrit Roelofs (Hockessin, Delaware);  Zhen-Yu Yang (Hockessin, Delaware)
ABSTRACT A fluorinated ion exchange polymer is prepared by grafting a monomer onto a base polymer, wherein the grafting monomer is selected from the group consisting of structure 1a, 1b and mixture thereof;
wherein Y is selected from the group consisting of —RFSO2F, —RFSO3M, —RSO2NH2 and —RFSO2N(M)SO2R2F, where in M is hydrogen, an alkali cation or ammonium; and RF and R2F are perfluorinated or partially fluorinated, and may optionally include ether oxygens; and n is between 1 and 2 for 1a, or n is between 1 and 3 for 1b. These ion exchange polymers are useful is preparing catalyst coated membranes and membrane electrode assemblies for fuel cells.
FILED Friday, June 25, 2004
APPL NO 10/570024
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/33
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564213 Bockelmann et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Eaton Corporation (Cleveland, Ohio)
INVENTOR(S) Thomas R. Bockelmann (Battle Creek, Michigan);  Kevin D. Beaty (Kalamazoo, Michigan);  Zhanijang Zou (Battle Creek, Michigan);  Xiaosong Kang (Battle Creek, Michigan)
ABSTRACT A battery control system for controlling a state of charge of a hybrid vehicle battery includes a detecting arrangement for determining a vehicle operating state or an intended vehicle operating state and a controller for setting a target state of charge level of the battery based on the vehicle operating state or the intended vehicle operating state. The controller is operable to set a target state of charge level at a first level during a mobile vehicle operating state and at a second level during a stationary vehicle operating state or in anticipation of the vehicle operating in the stationary vehicle operating state. The invention further includes a method for controlling a state of charge of a hybrid vehicle battery.
FILED Friday, August 13, 2004
APPL NO 10/917575
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Battery or capacitor charging or discharging
320/104
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564241 Barty et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Christopher P. J. Barty (Hayward, California);  Frederic V. Hartemann (San Ramon, California);  Dennis P. McNabb (Alameda, California);  Jason A. Pruet (Brentwood, California)
ABSTRACT The present invention utilizes novel laser-based, high-brightness, high-spatial-resolution, pencil-beam sources of spectrally pure hard x-ray and gamma-ray radiation to induce resonant scattering in specific nuclei, i.e., nuclear resonance fluorescence. By monitoring such fluorescence as a function of beam position, it is possible to image in either two dimensions or three dimensions, the position and concentration of individual isotopes in a specific material configuration. Such methods of the present invention material identification, spatial resolution of material location and ability to locate and identify materials shielded by other materials, such as, for example, behind a lead wall. The foundation of the present invention is the generation of quasimonochromatic high-energy x-ray (100's of keV) and gamma-ray (greater than about 1 MeV) radiation via the collision of intense laser pulses from relativistic electrons. Such a process as utilized herein, i.e., Thomson scattering or inverse-Compton scattering, produces beams having diameters from about 1 micron to about 100 microns of high-energy photons with a bandwidth of ΔE/E of approximately 10E−3.
FILED Tuesday, September 26, 2006
APPL NO 11/528182
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/304
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564387 Vawter et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) G. Allen Vawter (Corrales, New Mexico);  James Raring (Goleta, California);  Erik J. Skogen (Albuquerque, New Mexico)
ABSTRACT An optical analog-to-digital converter (ADC) is disclosed which converts an input optical analog signal to an output optical digital signal at a sampling rate defined by a sampling optical signal. Each bit of the digital representation is separately determined using an optical waveguide interferometer and an optical thresholding element. The interferometer uses the optical analog signal and the sampling optical signal to generate a sinusoidally-varying output signal using cross-phase-modulation (XPM) or a photocurrent generated from the optical analog signal. The sinusoidally-varying output signal is then digitized by the thresholding element, which includes a saturable absorber or at least one semiconductor optical amplifier, to form the optical digital signal which can be output either in parallel or serially.
FILED Friday, February 29, 2008
APPL NO 12/039931
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/137
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565657 Leung et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Vitus J. Leung (Albuquerque, New Mexico);  Cynthia A. Phillips (Albuquerque, New Mexico);  Michael A. Bender (East Northport, New York);  David P. Bunde (Urbana, Illinois)
ABSTRACT In a multiple processor computing apparatus, directional routing restrictions and a logical channel construct permit fault tolerant, deadlock-free routing. Processor allocation can be performed by creating a linear ordering of the processors based on routing rules used for routing communications between the processors. The linear ordering can assume a loop configuration, and bin-packing is applied to this loop configuration. The interconnection of the processors can be conceptualized as a generally rectangular 3-dimensional grid, and the MC allocation algorithm is applied with respect to the 3-dimensional grid.
FILED Tuesday, April 19, 2005
APPL NO 11/110206
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Virtual machine task or process management or task management/control
718/104
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07563451 Lin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Victor Shang-Yi Lin (Ames, Iowa);  Cheng-Yu Lai (Ames, Iowa);  Srdija Jeftinija (Ames, Iowa);  Dusan M. Jeftinija (Lexington, Kentucky)
ABSTRACT The invention provides an article comprising, a mesoporous silicate matrix, such as a particle, having one or more pores; and one or more releasable caps obstructing one or more of the pores. The articles are useful as delivery vehicles for encapsulated agents such as therapeutic agents, polynucleotides, polypeptides and the like.
FILED Thursday, April 22, 2004
APPL NO 10/830479
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563457 Cha et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer Cha (Berkeley, California);  Timothy J. Deming (Summerland, California);  Galen D. Stucky (Goleta, California);  Michael Wong (Houston, Texas);  Henrik Birkedal (Goleta, California);  Michael H. Bartl (Santa Barbara, California);  Jan L. Sumerel (Goleta, California)
ABSTRACT A design strategy for constructing hierarchically structured materials using nanoparticles and synthetic biopolymers has been developed. Block copolypeptides or homopolymer polyelectrolytes are used as structure-directing agents to arrange nanoparticles (composed of metals, metal non-oxides, metal oxides, or organics) into unusual microstructures, such as spheres, “apples” and “cups.” Hollow spheres can be made wherein nanoparticles of one composition are spatially oriented completely interior or exterior to nanoparticles of a second composition. These aggregates contain nanoparticles only in the shell walls, and maintain their hollowness upon calcination. These shapes can also be fabricated into films. These robust materials are anticipated to have great promise in applications that require surface catalysis, magnetic/electronic/optic properties, transport capabilities, and combinations thereof, such as drug delivery, packaging, catalysis, and sensors.
FILED Wednesday, October 02, 2002
APPL NO 10/263271
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/491
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564120 Lewis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Nathan S. Lewis (La Canada, California);  William J. Royea (Chicago, Illinois)
ABSTRACT Electrical structures and devices may be formed and include an organic passivating layer that is chemically bonded to a silicon-containing semiconductor material to improve the electrical properties of electrical devices. In different embodiments, the organic passivating layer may remain within finished devices to reduce dangling bonds, improve carrier lifetimes, decrease surface recombination velocities, increase electronic efficiencies, or the like. In other embodiments, the organic passivating layer may be used as a protective sacrificial layer and reduce contact resistance or reduce resistance of doped regions. The organic passivation layer may be formed without the need for high-temperature processing.
FILED Friday, September 02, 2005
APPL NO 11/219172
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/642
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564559 Choo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hyuck Choo (Albany, California);  Richard S. Muller (Kensington, California);  David Garmire (El Cerrito, California);  James W. Demmel (Berkeley, California);  Rishi Kant (Stanford, California)
ABSTRACT Provided herein are optical devices fabricated to include a reflective surface, actuators and stress-relieving structures. Systems containing such devices, and methods of manufacturing such devices, are also provided.
FILED Friday, June 02, 2006
APPL NO 11/446552
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564943 Sommer, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Spectramet, LLC (Bedford, Massachusetts)
INVENTOR(S) Edward J. Sommer, Jr. (Nashville, Tennessee);  Charles E. Roos (Nashville, Tennessee);  David B. Spencer (Bedford, Massachusetts);  R. Lynn Conley (Antioch, Tennessee)
ABSTRACT Disclosed herein is a metal sorting device including an X-ray tube, a dual energy detector array, a microprocessor, and an air ejector array. The device senses the presence of samples in the x-ray sensing region and initiates identifying and sorting the samples. After identifying and classifying the category of a sample, at a specific time, the device activates an array of air ejectors located at specific positions in order to place the sample in the proper collection bin.
FILED Thursday, August 03, 2006
APPL NO 11/498694
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/53
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565340 Herlocker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Science Foundation (NSF)
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) The State of Oregon Acting by and through the State Board of Higher Education on Behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Jonathan L. Herlocker (Philomath, Oregon);  Thomas G. Dietterich (Corvallis, Oregon)
ABSTRACT A method for assisting multi-tasking computer users includes receiving from a user a specification of a task being performed by the user or an indication of completion of a task, collecting state changes in multiple executing programs, predicting a current task being performed by the user based on a recent state change event, a past specification of a task being performed by the user, and past events and associated tasks. Based on the predicted current task, user interface elements in multiple executing programs are adapted to facilitate performance of the task. The method may also allow a user to specify a new task based on a task template derived from a completed task to facilitate completion of the new task. The task templates also may be shared among users, and active tasks may also be team tasks shared among users.
FILED Tuesday, May 30, 2006
APPL NO 11/443503
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/52
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07562581 Garverick et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Steven L. Garverick (Solon, Ohio);  Xinyu Yu (Cleveland, Ohio);  Lemi Toygur (Cleveland, Ohio);  Yunli He (Bedford, Ohio)
ABSTRACT Reliable and efficient sensing becomes increasingly difficult in harsher environments. A sensing module for high-temperature conditions utilizes a digital, rather than analog, implementation on a wireless platform to achieve good quality data transmission. The module comprises a sensor, integrated circuit, and antenna. The integrated circuit includes an amplifier, A/D converter, decimation filter, and digital transmitter. To operate, an analog signal is received by the sensor, amplified by the amplifier, converted into a digital signal by the A/D converter, filtered by the decimation filter to address the quantization error, and output in digital format by the digital transmitter and antenna.
FILED Friday, September 29, 2006
APPL NO 11/537488
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/777
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563615 Ponce
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Adrian Ponce (Altadena, California)
ABSTRACT An apparatus and method for automated monitoring of airborne bacterial spores. The apparatus is provided with an air sampler, a surface for capturing airborne spores, a thermal lysis unit to release DPA from bacterial spores, a source of lanthanide ions, and a spectrometer for excitation and detection of the characteristic fluorescence of the aromatic molecules in bacterial spores complexed with lanthanide ions. In accordance with the method: computer-programmed steps allow for automation of the apparatus for the monitoring of airborne bacterial spores.
FILED Friday, April 14, 2006
APPL NO 11/404382
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564539 Caldwell et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Ophir Corporation (Littleton, Colorado)
INVENTOR(S) Loren M. Caldwell (Fort Collins, Colorado);  Shoou-Yu Tang (Fort Collins, Colorado);  Martin J. O'Brien (Conifer, Colorado)
ABSTRACT A method for remotely sensing air outside a moving aircraft includes generating laser radiation within a swept frequency range. A portion of the laser radiation is projected from the aircraft into the air to induce scattered laser radiation. Filtered scattered laser radiation, filtered laser radiation, and unfiltered laser radiation are detected. At least one actual ratio is determined from data corresponding to the filtered scattered laser radiation and the unfiltered laser radiation. One or more air parameters are determined by correlating the actual ratio to at least one reference ratio.
FILED Monday, July 17, 2006
APPL NO 11/488259
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/28.500
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07562517 Kornecki
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Ted S. Kornecki (Aubum, Alabama)
ABSTRACT The rotary crimper for elevated crop beds is designed to crimp and mulch a field of crops with an elevated bed-type structure. The rotary crimper has a tubular inner roller and a plurality of crimping members extending from the inner roller. The crimping members have at least two projecting portions and at least one non-projecting portion. Structural support braces are disposed between the crimping members and crimping plates extend from the support braces. Additional crimping structures also extend the length of the inner tubular roller between the crimping members. In operation, the non-projecting portions of the crimping members and the crimping structures crimp the crops on the elevated portion of the beds, and the crimping member projecting portions and the crimping plates crimp the crops in the furrows between the elevated beds.
FILED Wednesday, September 17, 2008
APPL NO 12/212342
ART UNIT 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Harvesters
056/504
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563371 McCune-Sanders et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) William Jason McCune-Sanders (Burlington, Vermont);  Theodore Guy Roberts (Richmond, Vermont)
ABSTRACT A tubular plug flow digester system assembled from manufactured components, including a holding/heating tank (15) connected to a manifold (14) that feeds a single or multiple parallel injection pumps (12). These pumps force feedstock though check valves (13) and into single or parallel digester hulls. This hulls are composed of manufactured parts including tapered end sections (11) and hull sections (10) that can be assembled onsite to a configuration that accommodates operational needs. Biogas produced by this digester is pressurized due to a liquid column created by an elevated effluent outlet (25). Feedstock is inoculated with relevant microorganisms that promote the generation of methane-rich biogas. Inoculation members (26) positioned within the hulls shelter biofilms containing these microbes while allowing regions of the biofilm to slough or naturally release microbes into the flowing feedstock stream. Biogas is collected through a manifold (22) and its release is controlled by a regulator or a valve.
FILED Thursday, April 13, 2006
APPL NO 11/403473
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Liquid purification or separation
210/603
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07563609 Donnelly et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S)
ASSIGNEE(S) Genencor International, Inc. (Palo Alto, California)
INVENTOR(S) Mark Donnelly (Warrensville, Illinois);  William H. Eschenfeldt (St. Charles, Illinois);  Jonathan Trent (La Silva Beach, California)
ABSTRACT Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
FILED Tuesday, March 18, 2008
APPL NO 12/050455
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/189
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563860 Wu et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S) Yiliang Wu (Mississauga, Canada);  Ping Liu (Mississauga, Canada);  Beng S. Ong (Mississauga, Canada)
ABSTRACT An electronic device containing a polymer of Formula (I), Formula (II), or mixtures, or isomers thereof
wherein each R1 through R10 is independently hydrogen, alkyl, aryl, alkoxy, halogen, arylalkyl, cyano, or nitro providing that R1 and R2 exclude halogen, nitro and cyano; a and b represent the number of rings; and n represents the number of repeating groups or moieties.
FILED Thursday, April 06, 2006
APPL NO 11/399141
ART UNIT 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
528/380
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07562593 Engelbart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Roger W. Engelbart (St. Louis, Missouri);  Eugene A. Myers (St. Charles, Missouri);  Nancy L. Wood (Clayton, Missouri)
ABSTRACT Apparatus and methods for adjustably supporting probes are disclosed. In one embodiment, a sensor support assembly includes a base member adapted to be positioned proximate to and move along a surface of a material, the base member including a first outwardly projecting engagement member and a second outwardly projecting engagement member spaced apart from the first engagement member, and a support member coupled to the base member and including a boss adapted to engage a probe, wherein the first and second engagement members are adapted to engage the surface and to maintain a stand-off distance between the probe and the surface.
FILED Monday, December 11, 2006
APPL NO 11/609235
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/866.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07564943 Sommer, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Spectramet, LLC (Bedford, Massachusetts)
INVENTOR(S) Edward J. Sommer, Jr. (Nashville, Tennessee);  Charles E. Roos (Nashville, Tennessee);  David B. Spencer (Bedford, Massachusetts);  R. Lynn Conley (Antioch, Tennessee)
ABSTRACT Disclosed herein is a metal sorting device including an X-ray tube, a dual energy detector array, a microprocessor, and an air ejector array. The device senses the presence of samples in the x-ray sensing region and initiates identifying and sorting the samples. After identifying and classifying the category of a sample, at a specific time, the device activates an array of air ejectors located at specific positions in order to place the sample in the proper collection bin.
FILED Thursday, August 03, 2006
APPL NO 11/498694
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/53
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 07563581 Liu
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) State of Oregon acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon)
INVENTOR(S) Guowen Liu (Eugene, Oregon)
ABSTRACT This disclosure provides methods for detecting and localizing DNA mutations by DNA microarray. In various embodiments, the described methods include use of restriction endonuclease(s) and/or mismatch-recognition nuclease(s) to detect and/or localize mutations. In one representative method, reference and target DNA are digested using one or more restriction endonucleases, resultant DNA strands are labeled (e.g., using a DNA polymerase), and the labeled mixture of DNAs is hybridized to a microarray. In another representative method, reference and target DNA are denatured and annealed to form a mixture containing heteroduplex DNA, one or more mismatch-recognition nuclease(s) are used to nick or cleave at least a portion of the heteroduplex DNA, resultant DNA strands are labeled (e.g., using a DNA polymerase) and the labeled mixture of DNAs is hybridized to a microarray.
FILED Tuesday, April 29, 2008
APPL NO 12/111862
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07565340 Herlocker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Science Foundation (NSF)
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) The State of Oregon Acting by and through the State Board of Higher Education on Behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Jonathan L. Herlocker (Philomath, Oregon);  Thomas G. Dietterich (Corvallis, Oregon)
ABSTRACT A method for assisting multi-tasking computer users includes receiving from a user a specification of a task being performed by the user or an indication of completion of a task, collecting state changes in multiple executing programs, predicting a current task being performed by the user based on a recent state change event, a past specification of a task being performed by the user, and past events and associated tasks. Based on the predicted current task, user interface elements in multiple executing programs are adapted to facilitate performance of the task. The method may also allow a user to specify a new task based on a task template derived from a completed task to facilitate completion of the new task. The task templates also may be shared among users, and active tasks may also be team tasks shared among users.
FILED Tuesday, May 30, 2006
APPL NO 11/443503
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/52
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07562908 Nuccitelli
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Raytheon Comapny (Waltham, Massachusetts)
INVENTOR(S) Dominic S. Nuccitelli (Granada Hills, California)
ABSTRACT A flexible fluid conduit joint includes two or more flexible sections that preferentially bend about respective preferential bend axes of the sections. The sections each include a flexible bellows coupled at longitudinal ends to a pair of annular collars, and a pair of blade flexures or plates that are also attached to the annular collars. The blade flexures or plates prevent longitudinal expansion of the bellows, and inhibit bending of the flexible sections about an axis that is perpendicular to the plane or planes that the flexures define. Flexing of each section is thus preferentially channeled into a preferentially bending axis within or parallel to the plane or planes defined by the flexures. The sections have different orientations for their blade flexures or plates, allowing the flexible joint to act as a two-axis pivot that does not expand under fluid pressure.
FILED Tuesday, January 31, 2006
APPL NO 11/343675
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Pipe joints or couplings
285/226
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563459 Phillips
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Vetrans Affairs (Washington, District of Columbia)
INVENTOR(S) Catherine A. Phillips (Amarillo, Texas)
ABSTRACT The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.
FILED Friday, April 20, 2007
APPL NO 11/788643
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/577
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563628 Koch et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S) Thomas L. Koch (Califon, New Jersey);  Robert M. Pafchek (Blandon, Pennsylvania);  Mark A. Webster (Bethlehem, Pennsylvania)
ABSTRACT Disclosed is a method of fabricating an optical waveguide device including the steps of forming a mask over a waveguide core material layer so as to leave a portion of the layer exposed, and exposing the structure to an oxidizing environment to form an oxide layer on the waveguide core material layer at least in the exposed portion thereby defining the lateral dimension of the waveguide core. The resulting waveguide core has extremely smooth surfaces for low optical losses.
FILED Thursday, November 03, 2005
APPL NO 11/265931
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/31
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563875 Palys et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Sercretary of the Army (Washington, District of Columbia)
INVENTOR(S) Thomas J. Palys (Cascade, Maryland);  Randal J. Schoepp (Frederick, Maryland);  Kara E. Schmid (Frederick, Maryland)
ABSTRACT In this application is described the production of recombinant, chimeric, humanized antibodies specific for both BoNt/A and BoNT/B. The humanized antibodies were converted from a mouse anti-BoNT/A/B Fab fragment into a whole human IgG1 antibody. The antibodies are useful in assays for detecting human exposure to BoNT/A and BoNT/B.
FILED Monday, March 20, 2006
APPL NO 11/384712
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07563882 Zauderer et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Maurice Zauderer (Pittsford, New York);  Elizabeth E. Evans (Rochester, New York)
ABSTRACT The present invention relates to a novel human gene that is differentially expressed in human carcinoma. More specifically, the present invention relates to a polynucleotide encoding a novel human polypeptide named C35 that is overexpressed in human breast and bladder carcinoma. This invention also relates to C35 polypeptide, in particular C35 peptide epitopes and C35 peptide epitope analogs, as well as vectors, host cells, antibodies directed to C35 polypeptides, and the recombinant methods for producing the same. The present invention further relates to diagnostic methods for detecting carcinomas, including human breast carcinomas. The present invention further relates to the formulation and use of the C35 gene and polypeptides, in particular C35 peptide epitopes and C35 peptide epitope analogs, in immunogenic compositions or vaccines, to induce antibody or cell-mediated immunity against target cells, such as tumor cells, that express the C35 gene. The invention further relates to screening methods for identifying agonists and antagonists of C35 activity.
FILED Tuesday, June 10, 2003
APPL NO 10/457829
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.530
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, July 21, 2009.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2009/fedinvent-patents-20090721.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital