FedInvent™ Patents
Patent Details for Tuesday, September 22, 2009
This page was updated on Monday, March 27, 2023 at 01:27 AM GMT
Department of Health and Human Services (HHS)
| US 07591812 | Tamari |
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| INVENTOR(S) | Yehuda Tamari (Oyster Bay, New York) |
| ABSTRACT | The invention is a closed complaint venous reservoir with at least one pliable wall having at least three innovative features: 1) the venous reservoir incorporates means that purge gas bubbles entering the venous reservoir without the user intervention, 2) the venous reservoir incorporates a cardiotomy reservoir, and 3) the pliable wall of the venous reservoir is sealed within a rigid housing allowing control of its “atmospheric” pressure, and therefore the pressure at which that wall collapses. The combination of the three innovative features provides a collapsible compliant reservoir unitized with cardiotomy reservoir having air removal features and enabling vacuum augmented venous drainage (VAVD) that match that of the open hardshell venous-cardiotomy reservoir unit, while retaining the advantages of the closed soft shell venous reservoir. |
| FILED | Monday, July 24, 2006 |
| APPL NO | 11/491853 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/406 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591996 | Hwang et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Joo Ha Hwang (Bellevue, Washington); Andrew Brayman (Edmonds, Washington) |
| ABSTRACT | Selective occlusion of a blood vessel is achieved by selectively damaging endothelial cells at a target location in the blood vessel, resulting in the formation of a fibrin clot proximate to the damaged endothelial cells. Additional fibrinogen can then be introduced into the blood vessel if occlusion is not achieved, as the fibrinogen is converted to fibrin by enzymes released by the exposed thrombogenic tissue and activated platelets. Endothelial cells are selectively damaged using thermal effects induced by ultrasound, by mechanical effects induced by ultrasound, or by mechanical effects produced by a tool introduced into the blood vessel (such as a catheter-based tool). A particularly preferred technique for selectively damaging endothelial cells involves introducing an ultrasound activatable agent into the blood vessel, and causing cavitation in that agent using pulses of high-intensity focused ultrasound having a duration insufficient to induce thermal damage in adjacent perivascular tissue. |
| FILED | Wednesday, August 17, 2005 |
| APPL NO | 11/206639 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592003 | Nagai et al. |
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| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Yoshinori Nagai (Kanagawa, Japan); Paul W. Kincade (Nichols Hills, Oklahoma) |
| ABSTRACT | The discovery of Toll-like receptors (TLRs) on the surface of hematopoietic cells provides new methods for the stimulation and differentiation of various classes of progenitor cells. TLR2 and TLR4 agonists (natural ligands, mimetics, antibodies) are particularly useful in these methods. The cells can be isolated and used for various purpose including tissue regeneration and grafting. In contrast, antagonists of TLRs can be used to protect cells from various insults such as chemo- and radiotherapy, acute and chronic infection, and transplantation by inhibiting activation and differentiation. TLR2, TLR4 and TLR9 pathway antagonists (soluble TLR, mimetics, antibodies) are particularly useful in these methods. Cells can be isolated and used for various purposes including transplantation. |
| FILED | Friday, September 29, 2006 |
| APPL NO | 11/537200 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592007 | Gribben et al. |
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| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Genetics Institute, LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | John G. Gribben (Brookline, Massachusetts); Gordon J. Freeman (Brookline, Massachusetts); Lee M. Nadler (Newton, Massachusetts); Paul Rennert (Holliston, Massachusetts); Cindy L. Jellis (Londonderry, New Hampshire); Edward Greenfield (Randolph, Massachusetts); Gary S. Gray (Brookline, Massachusetts) |
| ABSTRACT | Isolated ligands which bind a molecule expressed on the surface of T cells and induce antigen specific apoptosis in activated T cells are disclosed. Preferably, the T cell surface molecule is CTLA4 and the ligand is a monoclonal anti-CTLA4 antibody that binds to an epitope of CTLA4 distinct from the binding sites of B7-1 and B7-2. Upon binding of the antibody to CTLA4 on an activated T cell, in the presence of an antigenic signal, antigen specific apoptosis is induced. The invention also describes a novel natural CTLA4 ligand, distinct from B7-1 and B7-2, which mediates induction of apoptosis. Pharmaceutical compositions of anti-CTLA4 antibodies or other isolated CTLA4 ligands which can be administered to subjects to induce T cell apoptosis, thereby clonally deleting antigen specific T cells, such as alloreactive T cells in transplantation situations or autoreactive T cells in autoimmune disorders, are also disclosed. Methods for inducing T cell apoptosis in vitro with an anti-CTLA4 antibody or other ligand of the invention together with an antigen specific signal are also disclosed, e.g., for use in purging alloreactive T cells from donor bone marrow prior to bone marrow transplantation to inhibit graft versus host disease. |
| FILED | Tuesday, December 09, 2003 |
| APPL NO | 10/732847 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/154.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592008 | Sligar et al. |
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| ASSIGNEE(S) | The Board of Trustees of the University of Illinois, a body corporate and politic of the State of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen G. Sligar (Urbana, Illinois); Timothy H. Bayburt (Urbana, Illinois); Mary A. Schuler (Urbana, Illinois); Natanya R. Civjan (Urbana, Illinois); Ylena V. Grinkova (Urbana, Illinois); Ilia G. Denisov (Urbana, Illinois); Stephen James Grimme (Urbana, Illinois) |
| ABSTRACT | The membrane scaffold proteins (MSP) of the present invention assemble with hydrophobic or partially hydrophobic proteins to form soluble nanoscale particles which preserve native structure and function; they are improved over liposomes and detergent micelles, in terms of stability and preservation of biological activity and native conformation. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles, which are robust in terms of integrity and maintenance of biological activity of incorporated proteins, facilitate pharmaceutical and biological research, structure/function correlations, structure determinations, bioseparations, and drug discovery. |
| FILED | Tuesday, January 11, 2005 |
| APPL NO | 11/033489 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592014 | Binley et al. |
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| ASSIGNEE(S) | Progenics Pharmaceuticals Inc. (Tarrytown, New York); Aaron Diamond Aids Research Centre (ADARC) (New York, New York) |
| INVENTOR(S) | James M. Binley (Brooklyn, New York); Norbert Schuelke (New City, New York); William C. Olson (Ossining, New York); Paul J. Maddon (Scarsdale, New York); John P. Moore (New York, New York) |
| ABSTRACT | This invention provides an isolated nucleic acid which comprises a nucleotide segment having a sequence encoding a viral envelope protein comprising a viral surface protein and a corresponding viral transmembrane protein wherein the viral envelope protein contains one or more mutations in amino acid sequence that enhance the stability of the complex formed between the viral surface protein and transmembrane protein. This invention also provides a viral envelope protein comprising a viral surface protein and a corresponding viral transmembrane protein wherein the viral envelope protein contains one or more mutations in amino acid sequence that enhance the stability of the complex formed between the viral surface protein and transmembrane protein. This invention further provides methods of treating HIV-1 infection. |
| FILED | Friday, October 28, 2005 |
| APPL NO | 11/261390 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592021 | Shankar et al. |
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| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Gita Natarajan Shankar (Saratoga, California); Rae Lyn Burke (San Francisco, California) |
| ABSTRACT | Formulations and methods for transmucosal delivery of a beneficial agent are described in which a pH-responsive component and a temperature-responsive component are combined and applied to a mucous membrane. The temperature-responsive component is a component that, in aqueous solutions, is capable of undergoing a temperature-dependent sol to gel phase transition. The formulations may be characterized as having bioadhesive properties, and are suitable for delivery of a variety of beneficial agents. |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/242680 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/484 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592141 | Schwinn et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Debra A. Schwinn (Durham, North Carolina); Daniel Laskowitz (Chapel Hill, North Carolina); Mihai V. Podgoreanu (Raleigh, North Carolina); Eugene W. Moretti (Durham, North Carolina) |
| ABSTRACT | The present invention provides a method of identifying a subject having a reduced risk of developing sepsis, comprising detecting at least one APOE3 allele in nucleic acid from the subject. |
| FILED | Tuesday, December 13, 2005 |
| APPL NO | 11/302064 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592147 | Glimcher et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard University (Cambridge, Massachusetts) |
| INVENTOR(S) | Laurie H. Glimcher (West Newton, Massachusetts); Eun Sook Hwang (Seoul, South Korea) |
| ABSTRACT | The instant invention is based, at least in part, on the dentification of a mechanism by which T-bet modulates IL2 production. The present invention pertains to methods of identifying agents that modulate the kinase-mediated interaction of T-bet with RelA, as well as methods of use therefore. |
| FILED | Tuesday, November 07, 2006 |
| APPL NO | 11/593811 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592152 | Prabhakar et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vikas Prabhakar (Cambridge, Massachusetts); Ishan Capila (Ashland, Massachusetts); Rahul Raman (Arlington, Massachusetts); Carlos Bosques (Cambridge, Massachusetts); Kevin Pojasek (Cambridge, Massachusetts); Ram Sasisekharan (Bedford, Massachusetts) |
| ABSTRACT | The invention relates to chondroitinase ABC I and uses thereof. In particular, the invention relates to recombinant and modified chondroitinase ABC I, their production and their uses. The chondroitinase ABC I enzymes of the invention are useful for a variety of purposes, including degrading and analyzing polysaccharides such as glycosaminoglycans (GAGs). These GAGs can include chondroitin sulfate, dermatan sulfate, unsulfated chondroitin and hyaluronan. The chondroitinase ABC I enzymes can also be used in therapeutic methods such as promoting nerve regeneration, promoting stroke recovery, treating spinal cord injury, treating epithelial disease, treating infections and treating cancer. |
| FILED | Wednesday, December 13, 2006 |
| APPL NO | 11/638094 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592154 | Miller et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Christine A. Miller (San Francisco, California); Ronen Mosseri (Tel Aviv, Israel); Stanley N. Cohen (Stanford, California) |
| ABSTRACT | Compositions and methods are provided for the use of SOS pathway targeted agents in antimicrobial formulations. The innate sensitivity of bacteria to antibiotics is increased by disrupting a mechanism that normally activates the bacterial SOS response or by inhibiting steps in the SOS response pathway itself. SOS response induction can result from exposure of bacteria to certain antibiotics, including β-lactam antibiotics and other agents that affect cell wall synthesis. By transiently delaying bacterial cell division, SOS response induction interferes with bacterial killing by ordinarily lethal concentrations of these drugs A pharmaceutical composition comprising an SOS targeted agent is administered to a patient suffering from a microbial infection, in combination with an antibiotic that induces an SOS response. The identification of the SOS pathway as a target for modulating antibiotic action provides a basis for further therapeutic development, through screening assays designed to detect molecules or genes that act on these pathways. |
| FILED | Tuesday, August 01, 2006 |
| APPL NO | 11/498208 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592161 | Lambowitz et al. |
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| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio); The University of Texas Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Alan M. Lambowitz (Austin, Texas); Huatao Guo (Alhambra, California); Michael Karberg (Austin, Texas) |
| ABSTRACT | The present invention provides a system and methods for analyzing the function of nucleotide integrases and modified group II introns. The system comprises a donor plasmid comprising a wild-type or modified group II intron, a recipient plasmid comprising a DNA recognition site and a promoterless reporter gene downstream of the DNA target site, and a host cell. The method comprises the steps of transforming a host cell with the donor and recipient plasmids, assaying for expression of the reporter gene, isolating plasmid DNA from the cotransformed cells, and analyzing the plasmid DNA to confirm that the group II intron has been inserted into the target sequence. The present invention also provides a method for simultaneously analyzing the activity of two or more modified nucleotide integrases. The present invention also relates to methods of preparing a library of donor plasmids containing a plurality of diverse modified group II intron DNA sequences. |
| FILED | Tuesday, October 22, 2002 |
| APPL NO | 10/277643 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592170 | Le Doux et al. |
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| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Joseph M. Le Doux (Decatur, Georgia); Martin L. Yarmush (Newton, Massachusetts); Jeffrey R. Morgan (Sharon, Massachusetts) |
| ABSTRACT | The invention provides new methods for purifying and concentrating viruses. The inventors have discovered that high molecular weight proteoglycans present in retroviral stocks are co-concentrated with the retroviruses, and can inhibit retroviral transduction. The new purification and concentration methods feature treatment of virus stock with an anionic polyelectrolyte and a cationic polyelectrolyte, followed by centrifugation. The new methods minimize the amount of proteoglycan co-precipitated with the infectious virus. |
| FILED | Tuesday, April 12, 2005 |
| APPL NO | 11/104161 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/239 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592174 | Sylvester et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Karl G. Sylvester (Los Altos, California); Monika Tataria (St. Louis, Missouri); Laurie Ailles (Palo Alto, California); Irving L. Weissman (Stanford, California) |
| ABSTRACT | Methods and compositions are provided for the identification and isolation of mammalian mesenchymal stem cells. The methods of the invention provide a means to obtain substantially homogeneous MSC populations. In some embodiments, the homogeneous MSC composition is stable in non-differentiating culture conditions, where the proportion of cells in the composition that have an MSC phenotype are maintained over multiple passages. |
| FILED | Friday, February 09, 2007 |
| APPL NO | 11/704611 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592188 | Hahn et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Klaus M. Hahn (Chapel Hill, North Carolina); Alexei Toutchkine (Arlington, Massachusetts) |
| ABSTRACT | The invention provides dyes, biosensors, and methods for using the dyes and biosensors to detect selected target molecules. The biosensors have a binding domain and a dye, or a dye which is attached directly to the target of interest. Binding domains contemplated by the invention include biomolecules or fragments of biomolecules that interact with target molecules of interest and can be specific to a given conformational state or covalent modification of the molecule (e.g. phosphorylation). In one embodiment, the binding domain of a biosensor is a single chain variable fragment (scFv) with a dye of the invention linked to a CDR3 region. The invention also provides environmentally sensitive dyes useful for detecting changes in the binding, conformational change, or posttranslational modification of the selected target. |
| FILED | Monday, March 14, 2005 |
| APPL NO | 11/079907 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592313 | Zheng et al. |
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| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Guoxing Zheng (Rockford, Illinois); Aoshuang Chen (Rockford, Illinois) |
| ABSTRACT | The thymus-derived CD4+CD25+ T cells belong to a subset of regulatory T cells potentially capable of suppressing the proliferation of pathogenic effector T cells. Intriguingly, these suppressor cells are themselves anergic, proliferating poorly to mitogenic stimulation in culture. The inventors have found that the 4-1BB co-stimulator receptor, best known for promoting the proliferation and survival of CD8+ T cells, also induces the proliferation of the CD4+CD25+ regulatory T cells both in culture and in vivo. The proliferating CD4+CD25+ T cells produce no detectable IL-2, suggesting that 4-1BB costimulation of these cells does not involve IL-2 production. The 4-1BB-expanded CD4+CD25+ T cells are functional, as they remain suppressive to other T cells in co-culture. These results support the notion that the peripheral expansion of the CD4+CD25+ T cells is controlled in part by co-stimulation. |
| FILED | Thursday, May 12, 2005 |
| APPL NO | 11/596706 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592317 | Weichselbaum et al. |
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| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Dana-Farber Cancer Institute (Boston, Massachusetts) |
| INVENTOR(S) | Ralph H. Weichselbaum (Chicago, Illinois); Dennis E. Hallahan (Park Ridge, Illinois); Donald W. Kufe (Wellesley, Massachusetts); Vikas P. Sukhatme (Newton Centre, Massachusetts) |
| ABSTRACT | The present disclosure demonstrates the successful use of constitutive promoters operatively linked to genes encoding radiosensitizing or radioprotecting factors, administered to cells, tissues, or patients in conjunction with radiation exposure. Also disclosed are pharmacological preparations to be used to increase the levels of radiosensitizing compounds such as TNF-α, or radioprotective compounds such as MnSOD, in specified tissues or tumors of a subject. |
| FILED | Thursday, August 11, 1994 |
| APPL NO | 08/289290 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592319 | Li et al. |
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| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Gloria C. Li (New York, New York); Paul W. J. J. Burgman (New York, New York) |
| ABSTRACT | This invention provides a method for increasing the susceptibility of a cell to DNA-damaging agents, comprising introducing into the cell an antisense oligonucleotide that specifically hybridizes to a nucleic acid encoding a DNA dependent protein kinase subunit so as to prevent expression of the DNA dependent protein kinase subunit; wherein the antisense oligonucleotide is in an amount sufficient to increase the sensitivity of the cell to heat, chemical, or radiation-induced DNA damage; and wherein the DNA dependent protein kinase subunit is a DNA dependent protein kinase catalytic subunit, a Ku70, or a Ku80. This invention also provides a method of treating a tumor in a subject, comprising administering to the subject an antisense oligonucleotide that specifically hybridizes to a nucleic acid encoding a DNA dependent protein kinase subunit so as to prevent expression of the DNA dependent protein kinase subunit; wherein the antisense oligonucleotide is in an amount sufficient to increase the sensitivity of the tumor to heat, chemical or radiation-induced DNA damage; and wherein the DNA dependent protein kinase subunit is a DNA dependent protein kinase catalytic subunit, a Ku70, or a Ku80. This invention provides an antisense oligonucleotide that specifically hybridizes to a nucleic acid encoding a DNA dependent protein kinase subunit, wherein the DNA dependent protein kinase subunit is a DNA, dependent protein kinase catalytic subunit, Ku70, or Ku80, so as to prevent expression of the DNA dependent protein kinase subunit. |
| FILED | Wednesday, November 12, 2003 |
| APPL NO | 10/712642 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592320 | DeBenedetti et al. |
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| INVENTOR(S) | Arrigo DeBenedetti (Shreveport, Louisiana); Robert J. DeFatta (Shreveport, Louisiana) |
| ABSTRACT | A novel gene therapy for cancer has been discovered, which unlike most prior approaches, does not require specific knowledge of the cancer cells, but instead targets a general characteristic that distinguishes cancer cells from normal cells, i.e., elevated eIF4E expression. The expression of a toxin or conditional toxin such as HTK is translationally repressed in normal cells by placing a complex 5′ UTR in front of its reading frame. In prototype experiments, this HTK mRNA, a transcriptional product of the BK-UTK vector, was translationally regulated so as to largely inhibit its production in normal murine and human cells, while cancer cells efficiently translated the protein, which a resulting increased sensitivity to GCV. Synthesis of the HTK protein from the BK-UTK vector (containing the 5′ UTR of Fibroblast growth factor-2 (“FGF-2”) readily occurred in a panel of murine and human breast carcinoma lines, but not in normal cell lines. Subcutaneous tumors and experimental lung metastases of the breast carcinoma line MM2MT in BALB/c mice were greatly reduced by transfection with the BK-UTK vector, followed by GCV administration. Both the BK-UTK and the BK-TK (control) vectors were effective in reducing lung metastasis following systemic delivery of the vectors and subsequent GCV administration. However, the BK-TK vector was highly toxic to mice while little to no toxicity was seen in mice treated with the BK-UTK vector. |
| FILED | Thursday, November 20, 2003 |
| APPL NO | 10/718163 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592421 | Ferrone et al. |
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| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York) |
| INVENTOR(S) | Soldano Ferrone (Buffalo, New York); Wei Luo (Getzville, New York); Xinhui Wang (Williamsville, New York) |
| ABSTRACT | The present invention provides peptide mimics for HLA class II antigens. The peptide mimics were identified by panning phage display peptide libraries with anti-HLA class II monoclonal antibodies. The peptide mimics inhibit the binding of an anti-HLA class II antigen antibody to HLA class II antigen positive cells and also elicit antibodies which can bind to HLA class II antigen positive cells. The identified peptide mimics can be used as immunogens for therapy of diseases related to cells expressing the HLA class II antigen, such as Non-Hodgkins Lymphoma. |
| FILED | Friday, March 19, 2004 |
| APPL NO | 10/804392 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592440 | Freier et al. |
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| ASSIGNEE(S) | Isis Pharmaceuticals, Inc. (Carlsbad, California); University of Utah (Salt Lake City, Utah) |
| INVENTOR(S) | Susan M. Freier (San Diego, California); Olga Matveeva (Salt Lake City, Utah); Alexander Tsodikov (Salt Lake City, Utah); Michael C. Giddings (Salt Lake City, Utah); Jacqueline R. Wyatt (Encinitas, California) |
| ABSTRACT | Methods for obtaining antisense oligonucleotides with activity against a desired target are provided. Methods of identifying oligonucleotide sequence motifs which are predictive of antisense oligonucleotide activity are provided, as are motifs identified according to this method. Methods of selecting effective antisense oligonucleotide sequences and effective antisense target sequences are provided, as are sequences selected according to these methods. In other methods of the invention, oligonucleotides are designed to hybridize to target sequences containing one or more activity-enhancing motifs. Antisense oligonucleotides designed according to these methods are also provided. |
| FILED | Wednesday, October 15, 2003 |
| APPL NO | 10/686317 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592501 | Wiles et al. |
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| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Michael V. Wiles (Somesville, Maine); Robert Taft (South West Harbor, Maine); Eva M. Eicher (Seal Cove, Maine) |
| ABSTRACT | The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals. |
| FILED | Wednesday, August 11, 2004 |
| APPL NO | 10/915840 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592503 | Baguisi et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Alexander Baguisi (Grafton, Massachusetts); Eric W. Overstrom (Grafton, Massachusetts) |
| ABSTRACT | The present invention pertains to methods for cloning animals. In particular, the invention includes methods of cloning an animal by combining a genome from an activated donor cell with an activated enucleated oocyte to thereby obtain a nuclear transfer embryo, and impregnating an animal with the nuclear transfer embryo in conditions suitable for gestation of a cloned animal. The invention further relates to methods of chemically enucleating an oocyte having a meiotic spindle apparatus by exposing the oocyte with a compound that destabilizes the meiotic spindle apparatus. |
| FILED | Friday, August 06, 2004 |
| APPL NO | 10/913013 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592806 | Josan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Sonal Josan (Mountain View, California); John M. Pauly (Stanford, California); Kim B. Pauly (Stanford, California) |
| ABSTRACT | A method for creating a magnetic resonance image of an object with at least a first species and a second species, wherein the first species has a first T2 time and the second species has a second T2 time longer than the first T2 time is provided. An excitation with an ultra short echo time using a pulse is provided, comprising a first subpulse that creates a transverse magnetization component for the first species and the second species and a second subpulse that creates a transverse magnetization for the first species and substantially returns the second species to a longitudinal axis, wherein the transverse magnetization component substantially decays for the first species during an interval between the first subpulse and the second subpulse. At least one echo is read. A magnetic resonance image is created from the at least one echo. |
| FILED | Friday, August 15, 2008 |
| APPL NO | 12/192347 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Measuring and testing 324/305 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592807 | Pineda et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Angel R. Pineda (Fullerton, California); Charles A. McKenzie (London, Canada); Huanzhou Yu (Mountain View, California); Scott B. Reeder (Middleton, Wisconsin) |
| ABSTRACT | A method of separating signals from at least two species in a body using echo-coherent time magnetic resonance imaging is provided. A plurality of echo signals is acquired at acquisition times optimized based on the noise properties of images with different variance with possibly correlated noise resulting in possibly asymmetrically positioned images with respect to an echo time. The plurality of echo signals is combined iteratively by using a maximum likelihood decomposition algorithm for non-identically distributed noise. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 11/738343 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593503 | Sukovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Xoran Technologies, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Predrag Sukovic (Birmingham, Michigan); Neal Clinthome (Ann Arbor, Michigan); Miodrag Rakic (Redondo Beach, California); James A. Bertolina (Portage, Michigan); Joseph Webster Stayman (Ann Arbor, Michigan) |
| ABSTRACT | A CT scanner includes a pair of shields to protect an operator from x-rays from the CT scanner. The CT scanner has a gantry that provides structural support and housing for the components including an x-ray source and a detector arranged on the gantry to face one another. Lead shields are located on opposing sides of the x-ray source and extend between the x-ray source and the detector. The CT scanner further includes a computer located on an opposing side of the gantry from the x-ray source and the detector. The lead shields rotate with the gantry and prevent the x-ray from reaching the operator while the CT scanner is in operation. |
| FILED | Wednesday, February 14, 2007 |
| APPL NO | 11/674748 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593559 | Toth et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Cynthia A. Toth (Chapel Hill, North Carolina); Marcin Stopa (Poznan, Poland); Bradley A. Bower (Hillsborough, North Carolina) |
| ABSTRACT | A method/system preserves annotations of different pathological conditions or changes that are recognized on cross-sections within a three dimensional volume of a patient's eye so that the annotations are maintained in a visible state in an en face projection produced with a SVP technique. it is thus possible to coregister the annotated conditions or changes with other types of two dimensional en face images such as images from other ophthalmic devices (e.g., angiography device, microperimetry device, autofluorescence device, fundal photography device.). The annotations are also maintained in a visible state in the coregistered image. |
| FILED | Friday, November 17, 2006 |
| APPL NO | 11/600913 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593776 | Loeb et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Gerald E. Loeb (South Pasadena, California); Jack Weissberg (Culver City, California); Nuria Rodriguez (Los Angeles, California) |
| ABSTRACT | A novel system and method for restoring functional movement of a paralyzed limb(s) or a prosthetic device. Stimulating one or more muscles of a patient using an implanted neuromuscular implants and sensing the response of the stimulated muscle by the implants, wherein the sensing the response is not limited to data related to patient's movement intention, the posture, muscle extension, M-Wave and EMG. A communication and control protocol to operate the system safely and efficiently, use of forward and reverse telemetry channels having a limited bandwidth capacity, and minimizing the adverse consequences caused by errors in data transmission and intermittent loss of power to the implants. Adjusting stimulation rates and phases of the stimulator in order to achieve an efficient control of muscle force while minimizing fatigue and therefore providing for smooth movements and dynamic increase of the strength in patient's muscle contraction. |
| FILED | Tuesday, July 03, 2007 |
| APPL NO | 11/773322 |
| ART UNIT | 3766 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D600641 | Starck |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | PHS General Design Services B.V. (Amsterdam, Netherlands) |
| INVENTOR(S) | Philippe Starck (Paris, France) |
| ABSTRACT | |
| FILED | Friday, January 02, 2009 |
| APPL NO | 29/330270 |
| ART UNIT | 2912 — Design |
| CURRENT CPC | Equipment for production, distribution, or transformation of energy D13/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07591225 | Cope et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Randall D. Cope (Ridgecrest, California); Gabriel H. Soto (Ridgecrest, California); John K. Kandell (Ridgecrest, California); Brian D. Dutton (Ridgecrest, California) |
| ABSTRACT | A self-contained fuze module, for installation on pieces of ordnance, having sensing devices and processing capability within the fuze module to determine whether conditions have been met to arm the ordnance. The fuze module is a unitary sealed module communicating with a launch vehicle via one or more communication/power buses. |
| FILED | Wednesday, July 18, 2007 |
| APPL NO | 11/779622 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591299 | Gordon et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Touchstone Research Laboratory, Ltd. (Triadelphia, West Virginia) |
| INVENTOR(S) | Brian L. Gordon (Wheeling, West Virginia); Gregg W. Wolfe (Wheeling, West Virginia) |
| ABSTRACT | A method and apparatus for the production of long lengths of continuous-fiber metal matrix composite prepeg ribbon or tape. The tape or ribbon is produced by bringing together multiple fiber tows into a formed bundle of fibers and infiltrating the bundle with metal using a continuous pultrusion process. Pultrusion is a preferred method of tape or ribbon manufacture since it places the fibers in tension during manufacture and avoids subsequent issues associated with buckling stress. |
| FILED | Wednesday, November 24, 2004 |
| APPL NO | 10/995274 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Metal founding 164/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591622 | de Jesus et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Horacio B. de Jesus (Hungtington Beach, California); Elio Dalmau (La Crescenta, California) |
| ABSTRACT | A nutmount apparatus includes a sleeve, a bushing insertable into the sleeve and a nut. The nutmount apparatus may further include a nut retainer for holding an internally threaded nut. The nutmount apparatus may be used, in conjunction with a threaded screw or bolt, to secure a first structure, such as an aircraft wall or cover panel, to a second structure, such as an aircraft frame. |
| FILED | Friday, July 22, 2005 |
| APPL NO | 11/188028 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Expanded, threaded, driven, headed, tool-deformed, or locked-threaded fastener 411/111 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591631 | Hendricks et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Gavin Hendricks (Manchester, Connecticut); Nils G. Dahl (Stonington, Connecticut); Kevin M. Plante (Coventry, Connecticut); Charles C. Wu (Glastonbury, Connecticut); Christopher J. Loconto (Worcester, Massachusetts) |
| ABSTRACT | A turbo machine includes a housing having a bearing compartment for receiving lubrication. The housing also provides a buffer compartment for receiving air, for example, compressor bleed air. A turbine shaft is supported within the housing on a bearing for rotation relative to the housing. The bearing is arranged within the bearing compartment. A seal is arranged between the turbine shaft and the housing and separates the bearing and buffer compartments. The seal includes opposing lubrication and air sides that are respectively exposed to the bearing and buffer compartments. The buffer tube is fluidly connected to a body of the buffer compartment. A buffer tube introduces flow generally tangential to an inner surface of the body for generating a swirl within the body. The buffer tube includes a velocity control device such a venturi arranged at an exit of the tube to control the velocity of the flow entering the body. An orifice plate is arranged upstream from the venturi to control the flow to a desired flow rate. The swirling flow within the body at the desired flow rate and velocity provides a uniform pressure gradient at idle having a large enough pressure magnitude to create the desired pressure differential across the seal. The increased pressure in the buffer compartment in the vicinity of the seal prevents leakage of lubricant past the seal at idle. |
| FILED | Friday, June 30, 2006 |
| APPL NO | 11/480267 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/111 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591897 | Sunkara et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Mahendra Kumar Sunkara (Louisville, Kentucky); Sreeram Vaddiraju (Mountain View, California); Miran Mozetic (Ljubljan, Slovenia); Uros Cvelbar (Idrija, Slovenia) |
| ABSTRACT | A process for the rapid synthesis of metal oxide nanoparticles at low temperatures and methods which facilitate the fabrication of long metal oxide nanowires. The method is based on treatment of metals with oxygen plasma. Using oxygen plasma at low temperatures allows for rapid growth unlike other synthesis methods where nanomaterials take a long time to grow. Density of neutral oxygen atoms in plasma is a controlling factor for the yield of nanowires. The oxygen atom density window differs for different materials. By selecting the optimal oxygen atom density for various materials the yield can be maximized for nanowire synthesis of the metal. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385015 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591996 | Hwang et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Joo Ha Hwang (Bellevue, Washington); Andrew Brayman (Edmonds, Washington) |
| ABSTRACT | Selective occlusion of a blood vessel is achieved by selectively damaging endothelial cells at a target location in the blood vessel, resulting in the formation of a fibrin clot proximate to the damaged endothelial cells. Additional fibrinogen can then be introduced into the blood vessel if occlusion is not achieved, as the fibrinogen is converted to fibrin by enzymes released by the exposed thrombogenic tissue and activated platelets. Endothelial cells are selectively damaged using thermal effects induced by ultrasound, by mechanical effects induced by ultrasound, or by mechanical effects produced by a tool introduced into the blood vessel (such as a catheter-based tool). A particularly preferred technique for selectively damaging endothelial cells involves introducing an ultrasound activatable agent into the blood vessel, and causing cavitation in that agent using pulses of high-intensity focused ultrasound having a duration insufficient to induce thermal damage in adjacent perivascular tissue. |
| FILED | Wednesday, August 17, 2005 |
| APPL NO | 11/206639 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592173 | Stamper et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David M. Stamper (Clarksburg, Maryland); Marianne Walch (Millsboro, Delaware); Darrell H. Hill (Monroeville, New Jersey) |
| ABSTRACT | Biofilm on glass beads deposited within a bottom portion of a vertically elongated bioreactor housing for possible experimental evaluation through a testing port in the housing which is also provided with inlet ports for aeration and infeed of nutrients with liquid. The biofilm collected within the housing chamber undergoes growth on glass slides within a cross-sectionally rectangular portion of the bioreactor housing from which the slides may be upwardly withdrawn under selective control without biofilm damage. The bioreactor housing arrangement also provides a high length to width ratio designed to enhance aeration. |
| FILED | Friday, April 16, 2004 |
| APPL NO | 10/826789 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/299.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592422 | Swiercz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Medical College of Ohio (Toledo, Ohio) |
| INVENTOR(S) | Rafal Swiercz (Bastrop, Texas); Steven H. Selman (Toledo, Ohio); Jerzy Jankun (Sylvania, Ohio); Joanna Chorostowska-Wynimko (Warsaw, Poland); Ewa Skrzypczak-Jankun (Sylvania, Ohio) |
| ABSTRACT | The present invention is based upon the discovery that modified plasminogen activator inhibitor type-I (PAI-1) in which two or more amino acid residues that do not contain a sulfhydryl group have been replaced with amino acid residues that contain a sulfhydryl group and, therefore, forms intramolecular disulfide bonds, have increased in vivo half-life. Also disclosed are the modified PAI-1 proteins, derivatives and analogs thereof, specific antibodies, nucleic acid molecules and host cells. Methods for producing modified PAI-1, derivatives and analogs are also provided. The invention further relates to Therapeutics, pharmaceutical compositions and method of using the composition for treatment. The invention may be used to inhibit angiogenesis in a subject, thereby treating diseases or conditions associated with undesired angiogenesis and cell proliferation. Such conditions include psoriasis, chronic inflammation, tumor invasion and metastasis and conditions in which angiogenesis is pathogenic. The modifide PAI-1 molecules of the present invention are useful for the treatment, prophylaxis, management and amelioration of cardiovascular diseases such as, but not limited to those that are related to hyperfibrinolysis, hemophilia, and vessel leakage syndrome. |
| FILED | Tuesday, March 04, 2003 |
| APPL NO | 10/506406 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592535 | Kanatzidis et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees operating Michingan State University (East Lansing, Michigan) |
| INVENTOR(S) | Mercouri Kanatzidis (Okemos, Michigan); Kuei-Fang Hsu (Chang Hua Hsien, Taiwan) |
| ABSTRACT | A thermoelectric material of the general formula Ag1−XMmM′Q2+m, wherein M is selected from the group consisting of Pb, Sn, Ca, Sr, Ba, divalent transition metals, and combinations thereof; M′ is selected from the group consisting of Bi, Sb, and combinations thereof; Q is selected from the group consisting of Se, Te, S, and combinations thereof; 8≦m≦24; and 0.01≦x≦0.7. In embodiments of the invention, the compositions exhibit n-type semiconductor properties. In preferred embodiments, x is from 0.1 to 0.3, and m is from 10 to 18. The compositions may be synthesized by adding stoichiometric amounts of starting materials comprising Ag, M, M′, and Q to a reaction vessel, heating the starting materials to a temperature and for a period of time sufficient to melt the materials, and cooling the reaction product at a controlled rate of cooling. |
| FILED | Wednesday, August 25, 2004 |
| APPL NO | 10/571338 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/241 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592539 | Peumans et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Peter Peumans (Palo Alto, California); Stephen R. Forrest (Princeton, New Jersey) |
| ABSTRACT | Solid state photosensitive devices including photovoltaic devices are provided which comprise a first electrode and a second electrode in superposed relation; and at least one isolated Light Harvesting Complex (LHC) between the electrodes. Preferred photosensitive devices comprise an electron transport layer formed of a first photoconductive organic semiconductor material, adjacent to the LHC, disposed between the first electrode and the LHC; and a hole transport layer formed of a second photoconductive organic semiconductor material, adjacent to the LHC, disposed between the second electrode and the LHC. Solid state photosensitive devices of the present invention may comprise at least one additional layer of photoconductive organic semiconductor material disposed between the first electrode and the electron transport layer; and at least one additional layer of photoconductive organic semiconductor material, disposed between the second electrode and the hole transport layer. Methods of generating photocurrent are provided which comprise exposing a photovoltaic device of the present invention to light. Electronic devices are provided which comprise a solid state photosensitive device of the present invention. |
| FILED | Friday, November 07, 2003 |
| APPL NO | 10/704226 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592679 | Kamins et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Theodore I. Kamins (Palo Alto, California); Philip J. Kuekes (Palo Alto, California); Carrie L. Donley (Chapel Hill, North Carolina); Jason J. Blackstock (Palo Alto, California) |
| ABSTRACT | A sensor includes at least two electrodes, and at least one nanowire extending substantially laterally between the electrodes. The at least one nanowire has at least two segments with a junction or connection formed therebetween. A sensing material changeable between at least two states is positioned adjacent to the junction or connection, and adjacent to at least a portion of each of the segments. |
| FILED | Thursday, October 19, 2006 |
| APPL NO | 11/583648 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/414 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592707 | Krishnamoorthy et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Ashok V. Krishnamoorthy (San Diego, California); John E. Cunningham (San Diego, California) |
| ABSTRACT | One embodiment of the present invention provides a system that facilitates precise inter-chip alignment for proximity communication and power delivery. The system includes a first integrated circuit chip, whose surface has etch pit wells. The system also includes a second integrated circuit chip, whose surface has corresponding etch pit wells configured to align with the etch pit wells of the first integrated circuit chip. A shaped structure is placed in an etch pit well of the first integrated circuit chip such that when the corresponding etch pit well of the second integrated circuit chip is substantially aligned with the etch pit well of the first integrated circuit chip, the shaped structure mates with both the etch pit well of the first integrated circuit chip and with the corresponding etch pit well of the second integrated circuit chip, thereby precisely aligning the first integrated circuit chip with the second integrated circuit chip. Besides aiding in alignment, the shaped structure also creates a conductive connection between the first integrated circuit chip and the second integrated circuit chip. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385445 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/777 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592727 | Doughty |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Samuel P. S. Doughty (Mount Ephraim, New Jersey) |
| ABSTRACT | A device for imposing a torque load upon rotating machinery comprises a rotary unit and plural electromagnetic units. The rotary unit includes a shaft and conductive disks discretely fastened thereto. Each electromagnetic unit includes a bracket-shaped magnetic core and one or more ferromagnetic pieces discretely fastened thereto. The device's shaft is joined end-to-end to the motor's shaft, permitting integral axial rotation of the device's shaft, the disks and the motor's shaft. Each electromagnetic unit is placed so that the core “brackets” the two extreme disks, while each piece is between two disks. During rotation, a wire (coiled around each core) conducts current of selected amperage so as to generate a magnetic field of sufficient intensity that a magnetic flux circuit is formed through the stationary core and pieces and the rotating disks, resulting in a Lorentz force associated with the magnetic field and eddy currents engendered in the disks. |
| FILED | Monday, August 01, 2005 |
| APPL NO | 11/194831 |
| ART UNIT | 2839 — Semiconductors/Memory |
| CURRENT CPC | Electrical generator or motor structure 310/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592962 | Horner et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rob Horner (San Diego, California); Dennis Bermeo (San Diego, California) |
| ABSTRACT | A EPC Tapered Slot Antenna Method (NC#098518). The method comprising operatively coupling an input feed to a tapered slot antenna pair, wherein said tapered slot antenna pair comprises a first antenna element and a second antenna element; and electronically coupling a conductive launch structure to the first and second element at a location between a lowest operating frequency phase center and a launch end of the tapered slot antenna pair. |
| FILED | Monday, July 09, 2007 |
| APPL NO | 11/775044 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/767 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593013 | Agutter et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | James Agutter (Salt Lake City, Utah); Stefano Foresti (Salt Lake City, Utah); Shaun Moon (Salt Lake City, Utah); Julio Bermudez (Salt Lake City, Utah); Yarden Livnat (Salt Lake City, Utah); Thomas Morahan (Salt Lake City, Utah) |
| ABSTRACT | A visualization system for heterogeneous data sets comprises: a unique visualization interface created by a visualization engine. The visualization interface comprises a first area defining a center of attention, second area defining a parameter space and a plurality of correlation elements. The first area is a two-dimensional space for the display of items of interest. The second area provides a space in which parameters associated with the items of interest can be displayed. The correlation elements indicate relationships and their strength between items of interest and parameters in the second area. The visualization engine preferably comprises an input module, a control module, a retrieving module, a rendering module, and an analysis module. These components are coupled together to receive input from a user, retrieve data from a data source, and present the unique visualization interface to the user. |
| FILED | Thursday, March 09, 2006 |
| APPL NO | 11/373085 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/440 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593250 | Naumov et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Alaska) |
| INVENTOR(S) | Ivan I. Naumov (Fayetteville, Arkansas); Laurent M. Bellaiche (Fayetteville, Arkansas); Sergey A. Prosandeev (Fayetteville, Arkansas); Inna V. Ponomareva (Fayetteville, Arkansas); Igor A. Kornev (Fayetteville, Arkansas) |
| ABSTRACT | A ferroelectric nanostructure formed as a low dimensional nano-scale ferroelectric material having at least one vortex ring of polarization generating an ordered toroid moment switchable between multi-stable states. A stress-free ferroelectric nanodot under open-circuit-like electrical boundary conditions maintains such a vortex structure for their local dipoles when subject to a transverse inhomogeneous static electric field controlling the direction of the macroscopic toroidal moment. Stress is also capable of controlling the vortex's chirality, because of the electromechanical coupling that exists in ferroelectric nanodots. |
| FILED | Friday, June 08, 2007 |
| APPL NO | 11/811444 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Static information storage and retrieval 365/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593454 | Rasmussen |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ITT Manufacturing Enterprises, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Donald John Rasmussen (Fort Wayne, Indiana) |
| ABSTRACT | A method of correcting phase error of a phase shift keyed (PSK) signal includes (a) receiving a signal modulated by a spreading sequence; (b) despreading the received signal using a receiver spreading sequence similar to the spreading sequence of step (a); (c) calculating a crosscorrelation profile between the receiver spreading sequence and the received signal; and (d) calculating an autocorrelation profile of the receiver spreading sequence to determine a spreading code property (SCP). The method also includes (e) estimating a timing error in alignment between the autocorrelation and the crosscorrelation profiles; and (f) correcting a phase error of the signal despread in step (c), by using the SCP and the estimated timing error. |
| FILED | Wednesday, December 21, 2005 |
| APPL NO | 11/314123 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593489 | Koshy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | John C. Koshy (Jackson, New Jersey); Joseph C. Liberti (Howell, New Jersey); Timothy R. Hoerning (Roselle Park, New Jersey) |
| ABSTRACT | A STBICM MIMO receiver includes a plurality of demappers for demapping a plurality of complex symbols transmitted by a STBICM MIMO transmitter. Each demapper is configured to have one or more complex symbols associated therewith and is responsible for demapping its associated complex symbols. |
| FILED | Tuesday, March 14, 2006 |
| APPL NO | 11/374835 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/340 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593492 | Lande |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Mark Lande (Nashua, New Hampshire) |
| ABSTRACT | A high quality real-time Turbo-Mud processing system that chooses between a high complexity multi-user detectors that results in better estimates of the bit streams and computationally low linear-based-MUD/Turbo-MUD at each MUD window in each Turbo Iteration. In one embodiment this technique optimizes both the BER and the computational complexity of the receiver by using low complexity MUDs to reduce the number of symbols that the high complexity MUDs need to process. The present invention also provides an efficient means of estimating symbols transmitted in a multi-user environment in overloaded or super-saturated conditions. |
| FILED | Friday, September 15, 2006 |
| APPL NO | 11/532125 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/346 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593587 | Rosario |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Dalton S. Rosario (Germantown, Maryland) |
| ABSTRACT | A method of detecting an image anomaly (target) within a scene represented by image data comprises obtaining test data from a test window within the scene, combining the test data with reference data to generate combined data, then comparing the combined data with either the test data or the reference data. An improved image analyzer includes a computational unit configured to execute this method. In one example, image data is generated by a hyperspectral imager. |
| FILED | Friday, July 01, 2005 |
| APPL NO | 11/171366 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593644 | Kaertner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Franz X. Kaertner (Newton, Massachusetts); Jung Won Kim (Boston, Massachusetts); Michael Perrott (Cambridge, Massachusetts) |
| ABSTRACT | A RF-synchronization system includes a laser that creates pulse trains for synchronization. A modulation means transfers the timing information of the pulse train into an amplitude modulation of an optical or electronic system. A synchronization module changes the driving frequency of the modulation means until it reaches a phase-locked state with the pulse train. |
| FILED | Tuesday, May 10, 2005 |
| APPL NO | 11/125800 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593702 | Lie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Donald Y. C. Lie (San Diego, California); Jeremy Daniel Popp (San Diego, California) |
| ABSTRACT | Open-Loop RF Transmitter Output Power Control for Increased Power Efficiency (NC #98068) method includes determining a desired RF output power and obtaining a battery voltage value; determining a supply control voltage, a bias control voltage and a highest power efficiency; and transmitting selected values of the supply control voltage and the bias control voltage to supply control circuitry and bias control circuitry. |
| FILED | Tuesday, June 06, 2006 |
| APPL NO | 11/449183 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/127.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593835 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Spectral Sciences, Inc. (Burlington, Massachusetts) |
| INVENTOR(S) | Gail P. Anderson (Boulder, Colorado); Alexander Berk (Canton, Massachusetts); Prabhat K. Acharya (Burlington, Massachusetts); Larry S. Bernstein (Lexington, Massachusetts); Steven M. Adler-Golden (Newtonville, Massachusetts); Jamine Lee (Burlington, Massachusetts); Leonid Muratov (Woburn, Massachusetts) |
| ABSTRACT | A radiative transport band model method for prediction and analysis of high spectral resolution radiometric measurements. Atomic and molecular line center absorption is determined from finite spectral bin equivalent widths. A mathematically exact expansion for finite bin equivalent widths provides high accuracy at any desired spectral resolution. The temperature and pressure dependent Voigt line tail spectral absorption contributing to each spectral bin is pre-computed and fit to Padé approximants for rapid and accurate accounting of neighboring-to-distant lines. A specific embodiment has been incorporated into the MODTRAN™ radiation transport model. |
| FILED | Wednesday, April 05, 2006 |
| APPL NO | 11/398696 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07594111 | Kiriansky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vladimir L. Kiriansky (Mountain View, California); Derek L. Bruening (Cambridge, Massachusetts); Saman P. Amarasinghe (Waltham, Massachusetts) |
| ABSTRACT | Hijacking of an application is prevented by monitoring control flow transfers during program execution in order to enforce a security policy. At least three basic techniques are used. The first technique, Restricted Code Origins (RCO), can restrict execution privileges on the basis of the origins of instruction executed. This distinction can ensure that malicious code masquerading as data is never executed, thwarting a large class of security attacks. The second technique, Restricted Control Transfers (RCT), can restrict control transfers based on instruction type, source, and target. The third technique, Un-Circumventable Sandboxing (UCS), guarantees that sandboxing checks around any program operation will never be bypassed. |
| FILED | Thursday, December 18, 2003 |
| APPL NO | 10/740063 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/166 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07594260 | Porras et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Phillip Andrew Porras (Cupertino, California); Alfonso Valdes (San Carlos, California) |
| ABSTRACT | A method of network surveillance includes receiving network packets handled by a network entity and building at least one long-term and a least one short-term statistical profile from a measure of the network packets that monitors data transfers, errors, or network connections. A comparison of the statistical profiles is used to determine whether the difference between the statistical profiles indicates suspicious network activity. |
| FILED | Monday, May 05, 2003 |
| APPL NO | 10/429611 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Information security 726/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D600522 | Hillman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Paul D. Hillman (Albuquerque, New Mexico) |
| ABSTRACT | |
| FILED | Wednesday, April 16, 2008 |
| APPL NO | 29/306820 |
| ART UNIT | 2914 — Design |
| CURRENT CPC | Tools and hardware D8/72 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07591131 | Easley, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | William Lanier Easley, Jr. (West Peoria, Illinois); David Michael Milam (Dunlap, Illinois); Stephan Donald Roozenboom (Washington, Illinois); Michael Steven Bond (Chillicothe, Illinois); Amir Kapic (Dunlap, Illinois) |
| ABSTRACT | An exhaust treatment system for an engine is disclosed and may have an air induction circuit, an exhaust circuit, and an exhaust recirculation circuit. The air induction circuit may be configured to direct air into the engine. The exhaust circuit may be configured to direct exhaust from the engine and include a turbine driven by the exhaust, a particulate filter disposed in series with and downstream of the turbine, and a catalytic device disposed in series with and downstream of the particulate filter. The exhaust recirculation circuit may be configured to selectively redirect at least some of the exhaust from between the particulate filter and the catalytic device to the air induction circuit. The catalytic device is selected to create backpressure within the exhaust circuit sufficient to ensure that, under normal engine operating conditions above low idle, exhaust can flow into the air induction circuit without throttling of the air. |
| FILED | Thursday, November 30, 2006 |
| APPL NO | 11/606332 |
| ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Power plants 060/278 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591132 | Viola |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | GM Global Technology Operations, Inc. (Detroit, Michigan) |
| INVENTOR(S) | Michael B. Viola (Macomb Township, Michigan) |
| ABSTRACT | An exhaust aftertreatment system for an internal combustion engine is provided including an apparatus and method to inject a reductant into the exhaust gas feedstream. Included is a fuel metering device adapted to inject reductant into the exhaust gas feedstream and a controllable pressure regulating device. A control module is operatively connected to the reductant metering device and the controllable pressure regulating device, and, adapted to effect flow of reductant into the exhaust gas feedstream over a controllable flow range. |
| FILED | Wednesday, September 20, 2006 |
| APPL NO | 11/533425 |
| ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Power plants 060/286 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591150 | Turner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Terry D. Turner (Ammon, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho) |
| ABSTRACT | An apparatus and method for producing liquefied natural gas. A liquefaction plant may be coupled to a source of unpurified natural gas, such as a natural gas pipeline at a pressure letdown station. A portion of the gas is drawn off and split into a process stream and a cooling stream. The cooling stream passes through an expander creating work output. A compressor may be driven by the work output and compresses the process stream. The compressed process stream is cooled, such as by the expanded cooling stream. The cooled, compressed process stream is expanded to liquefy the natural gas. A gas-liquid separator separates a vapor from the liquid natural gas. A portion of the liquid gas is used for additional cooling. Gas produced within the system may be recompressed for reintroduction into a receiving line or recirculation within the system for further processing. |
| FILED | Monday, May 15, 2006 |
| APPL NO | 11/383411 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Refrigeration 062/613 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591197 | Bell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Perry M. Bell (Tracy, California); Allen T. Christian (Madison, Wisconsin); Christopher G. Bailey (Pleasanton, California); Ladona Willis (Manteca, California); Donald A. Masquelier (Tracy, California); Shanavaz L. Nasarabadi (Livermore, California) |
| ABSTRACT | A system for sampling air and collecting particles entrained in the air that potentially include bioagents. The system comprises providing a receiving surface, directing a liquid to the receiving surface and producing a liquid surface. Collecting samples of the air and directing the samples of air so that the samples of air with particles entrained in the air impact the liquid surface. The particles potentially including bioagents become captured in the liquid. The air with particles entrained in the air impacts the liquid surface with sufficient velocity to entrain the particles into the liquid but cause minor turbulence. The liquid surface has a surface tension and the collector samples the air and directs the air to the liquid surface so that the air with particles entrained in the air impacts the liquid surface with sufficient velocity to entrain the particles into the liquid, but cause minor turbulence on the surface resulting in insignificant evaporation of the liquid. |
| FILED | Tuesday, August 01, 2006 |
| APPL NO | 11/497918 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/863.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591310 | Minderhoud et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | Johannes Kornelis Minderhoud (Amsterdam, Netherlands); Richard Gene Nelson (Katy, Texas); Augustinus Wilhelmus Maria Roes (Houston, Texas); Robert Charles Ryan (Houston, Texas); Vijay Nair (Katy, Texas) |
| ABSTRACT | A method includes producing formation fluid from a subsurface in situ heat treatment process. The formation fluid is separated to produce a liquid stream and a gas stream. At least a portion of the liquid stream is provided to a hydrotreating unit. At least a portion of selected in situ heat treatment clogging compositions in the liquid stream are removed to produce a hydrotreated liquid stream by hydrotreating at least a portion of the liquid stream at conditions sufficient to remove the selected in situ heat treatment clogging compositions. |
| FILED | Friday, October 20, 2006 |
| APPL NO | 11/584803 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/267 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591834 | Buckley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Patrick R. Buckley (New York, New York); Duncan J. Maitland (Pleasant Hill, California) |
| ABSTRACT | A shape memory material with integrated actuation using embedded particles. One embodiment provides a shape memory material apparatus comprising a shape memory material body and magnetic pieces in the shape memory material body. Another embodiment provides a method of actuating a device to perform an activity on a subject comprising the steps of positioning a shape memory material body in a desired position with regard to the subject, the shape memory material body capable of being formed in a specific primary shape, reformed into a secondary stable shape, and controllably actuated to recover the specific primary shape; including pieces in the shape memory material body; and actuating the shape memory material body using the pieces causing the shape memory material body to be controllably actuated to recover the specific primary shape and perform the activity on the subject. |
| FILED | Friday, March 26, 2004 |
| APPL NO | 10/810422 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Surgery 66/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591871 | Gerung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Henry Gerung (Albuquerque, New Mexico); Timothy J. Boyle (Kensington, Maryland); Scott D. Bunge (Cuyahoga Falls, Ohio) |
| ABSTRACT | A method for providing a route for the synthesis of a Ge(0) nanometer-sized material from. A Ge(II) precursor is dissolved in a ligand heated to a temperature, generally between approximately 100° C. and 400° C., sufficient to thermally reduce the Ge(II) to Ge(0), where the ligand is a compound that can bond to the surface of the germanium nanomaterials to subsequently prevent agglomeration of the nanomaterials. The ligand encapsulates the surface of the Ge(0) material to prevent agglomeration. The resulting solution is cooled for handling, with the cooling characteristics useful in controlling the size and size distribution of the Ge(0) materials. The characteristics of the Ge(II) precursor determine whether the Ge(0) materials that result will be nanocrystals or nanowires. |
| FILED | Thursday, February 17, 2005 |
| APPL NO | 11/060157 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/362 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591897 | Sunkara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Mahendra Kumar Sunkara (Louisville, Kentucky); Sreeram Vaddiraju (Mountain View, California); Miran Mozetic (Ljubljan, Slovenia); Uros Cvelbar (Idrija, Slovenia) |
| ABSTRACT | A process for the rapid synthesis of metal oxide nanoparticles at low temperatures and methods which facilitate the fabrication of long metal oxide nanowires. The method is based on treatment of metals with oxygen plasma. Using oxygen plasma at low temperatures allows for rapid growth unlike other synthesis methods where nanomaterials take a long time to grow. Density of neutral oxygen atoms in plasma is a controlling factor for the yield of nanowires. The oxygen atom density window differs for different materials. By selecting the optimal oxygen atom density for various materials the yield can be maximized for nanowire synthesis of the metal. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385015 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591957 | Carr |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | RAPT Industries, Inc. (Fremont, California) |
| INVENTOR(S) | Jeffrey W. Carr (Livermore, California) |
| ABSTRACT | Reactive atom plasma processing can be used to shape, polish, planarize and clean the surfaces of difficult materials with minimal subsurface damage. The apparatus and methods use a plasma torch, such as a conventional ICP torch. The workpiece and plasma torch are moved with respect to each other, whether by translating and/or rotating the workpiece, the plasma, or both. The plasma discharge from the torch can be used to shape, planarize, polish, and/or clean the surface of the workpiece, as well as to thin the workpiece. The processing may cause minimal or no damage to the workpiece underneath the surface, and may involve removing material from the surface of the workpiece. |
| FILED | Thursday, November 01, 2001 |
| APPL NO | 10/002483 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Etching a substrate: Processes 216/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591979 | Hill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | David E. Hill (Knoxville, Tennessee); Miguel Rodriquez, Jr. (Oak Ridge, Tennessee); Elias Greenbaum (Knoxville, Tennessee) |
| ABSTRACT | An automatic, self-contained device for detecting toxic agents in a water supply includes an analyzer for detecting at least one toxic agent in a water sample, introducing means for introducing a water sample into the analyzer and discharging the water sample from the analyzer, holding means for holding a water sample for a pre-selected period of time before the water sample is introduced into the analyzer, and an electronics package that analyzes raw data from the analyzer and emits a signal indicating the presence of at least one toxic agent in the water sample. |
| FILED | Monday, October 20, 2003 |
| APPL NO | 10/689316 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591984 | Bulian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Christopher J. Bulian (Yankton, South Dakota); Robert C. Dye (Los Alamos, New Mexico); Steven F. Son (Los Alamos, New Mexico); Betty S. Jorgensen (Jemez Springs, New Mexico); W. Lee Perry (Jemez Springs, New Mexico) |
| ABSTRACT | Tungsten trioxide hydrate (WO3.H2O) was prepared from a precursor solution of ammonium paratungstate in concentrated aqueous hydrochloric acid. The precursor solution was rapidly added to water, resulting in the crash precipitation of a yellow white powder identified as WO3.H2O nanosized platelets by x-ray diffraction and scanning electron microscopy. Annealing of the powder at 200° C. provided cubic phase WO3 nanopowder, and at 400° C. provided WO3 nanopowder as a mixture of monoclinic and orthorhombic phases. |
| FILED | Monday, July 28, 2003 |
| APPL NO | 10/629489 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592043 | Burrows et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Paul E. Burrows (Kennewick, Washington); Linda S. Sapochak (Kennewick, Washington) |
| ABSTRACT | A method and apparatus for forming patterned coatings of thin film, non-polymerizable compounds on a substrate. A mixture of the non-polymerizable compound and a liquid carrier is pumped into the interior of a heated evaporation box having an internal temperature sufficient to convert substantially all of the non-polymerizable compound and liquid carrier to a gaseous form. The non-polymerizable compound and liquid carrier are then removed from the evaporation box via exit slit in the evaporation box. Adjacent to the exit slit, and maintained in a vacuum, is a first substrate upon which the non-polymerizable compound condenses. The first substrate is in motion, for example on a web roller, thereby allowing a continuous coating of the non-polymerizable compound to be applied to the first substrate. Once the non-polymerizable compound is applied to one side of the first substrate, an energy source is then directed toward the opposite side of the first substrate. In this manner, a portion of the non-polymerizable compound is removed from the first substrate. A second substrate is then provided adjacent to the first substrate, and the non-polymerizable compound is thereby transferred from the first substrate onto the second substrate. By repeatedly transferring portions of the non-polymerizable material from the first substrate to the second substrate in this manner, the thin film, non-polymerizable materials can be formed onto the second substrate in a predetermined pattern, and in a continuous and highly efficient process. |
| FILED | Monday, February 14, 2005 |
| APPL NO | 11/057905 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/248.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592090 | Seabaugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | NexTech Materials, Ltd. (Lewis Center, Ohio) |
| INVENTOR(S) | Matthew M. Seabaugh (Columbus, Ohio); Scott L. Swartz (Columbus, Ohio) |
| ABSTRACT | The invention relates to perovskite oxide electrode materials in which one or more of the elements Mg, Ni, Cu, and Zn are present as minority components that enhance electrochemical performance, as well as electrode products with these compositions and methods of making the electrode materials. Such electrodes are useful in electrochemical system applications such as solid oxide fuel cells, ceramic oxygen generation systems, gas sensors, ceramic membrane reactors, and ceramic electrochemical gas separation systems. |
| FILED | Tuesday, September 20, 2005 |
| APPL NO | 11/231340 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592139 | West et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia National Laboratories (Liverpool, California) |
| INVENTOR(S) | Jason A. A. West (Castro Valley, California); Kyle W. Hukari (San Ramon, California); Kamlesh D. Patel (Dublin, California); Kenneth A. Peterson (Albuquerque, New Mexico); Ronald F. Renzi (Tracy, California) |
| ABSTRACT | Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores are described. Systems for direct analysis are disclosed including thermal lysers coupled to sample preparation stations. Integrated systems capable of performing sample lysis, labeling and protein fingerprint analysis of biological material, for example, vegetative bacterial cells, bacterial spores and viruses are provided. |
| FILED | Wednesday, February 16, 2005 |
| APPL NO | 11/059079 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592282 | Ginosar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Daniel M. Ginosar (Idaho Falls, Idaho); Lucia Petkovic (Idaho Falls, Idaho) |
| ABSTRACT | A method of modifying an alkylation catalyst to reduce the formation of condensed hydrocarbon species thereon. The method comprises providing an alkylation catalyst comprising a plurality of active sites. The plurality of active sites on the alkylation catalyst may include a plurality of weakly acidic active sites, intermediate acidity active sites, and strongly acidic active sites. A base is adsorbed to a portion of the plurality of active sites, such as the strongly acidic active sites, selectively poisoning the strongly acidic active sites. A method of modifying the alkylation catalyst by providing an alkylation catalyst comprising a pore size distribution that sterically constrains formation of the condensed hydrocarbon species on the alkylation catalyst or by synthesizing the alkylation catalyst to comprise a decreased number of strongly acidic active sites is also disclosed, as is a method of improving a regeneration efficiency of the alkylation catalyst. |
| FILED | Thursday, November 11, 2004 |
| APPL NO | 10/986742 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592291 | Rollins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Batelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Harry W. Rollins (Idaho Falls, Idaho); Lucia M. Petkovic (Idaho Falls, Idaho); Daniel M. Ginosar (Idaho Falls, Idaho) |
| ABSTRACT | A precursor to a catalytic structure comprising zinc oxide and copper oxide. The zinc oxide has a sheet-like morphology or a spherical morphology and the copper oxide comprises particles of copper oxide. The copper oxide is reduced to copper, producing the catalytic structure. The catalytic structure is fabricated by a hydrothermal process. A reaction mixture comprising a zinc salt, a copper salt, a hydroxyl ion source, and a structure-directing agent is formed. The reaction mixture is heated under confined volume conditions to produce the precursor. The copper oxide in the precursor is reduced to copper. A method of hydrogenating a carbon oxide using the catalytic structure is also disclosed, as is a system that includes the catalytic structure. |
| FILED | Wednesday, March 21, 2007 |
| APPL NO | 11/688930 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592440 | Freier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Isis Pharmaceuticals, Inc. (Carlsbad, California); University of Utah (Salt Lake City, Utah) |
| INVENTOR(S) | Susan M. Freier (San Diego, California); Olga Matveeva (Salt Lake City, Utah); Alexander Tsodikov (Salt Lake City, Utah); Michael C. Giddings (Salt Lake City, Utah); Jacqueline R. Wyatt (Encinitas, California) |
| ABSTRACT | Methods for obtaining antisense oligonucleotides with activity against a desired target are provided. Methods of identifying oligonucleotide sequence motifs which are predictive of antisense oligonucleotide activity are provided, as are motifs identified according to this method. Methods of selecting effective antisense oligonucleotide sequences and effective antisense target sequences are provided, as are sequences selected according to these methods. In other methods of the invention, oligonucleotides are designed to hybridize to target sequences containing one or more activity-enhancing motifs. Antisense oligonucleotides designed according to these methods are also provided. |
| FILED | Wednesday, October 15, 2003 |
| APPL NO | 10/686317 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592462 | Huynh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, Minnesota) |
| INVENTOR(S) | My Hang V. Huynh (Los Alamos, New Mexico) |
| ABSTRACT | Lead-free primary explosives of the formula [MII(A)R(BX)S](CY)T, where A is 1,5-diaminotetrazole, and syntheses thereof are described. Substantially stoichiometric equivalents of the reactants lead to high yields of pure compositions thereby avoiding dangerous purification steps. |
| FILED | Thursday, February 15, 2007 |
| APPL NO | 11/707610 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592602 | Ziock |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Klaus-Peter Ziock (Clinton, Tennessee) |
| ABSTRACT | In a vehicle, a single detector plane simultaneously measures radiation coming through two coded-aperture masks, one on either side of the detector. To determine which side of the vehicle a source is, the two shadow masks are inverses of each other, i.e., one is a mask and the other is the anti-mask. All of the data that is collected is processed through two versions of an image reconstruction algorithm. One treats the data as if it were obtained through the mask, the other as though the data is obtained through the anti-mask. |
| FILED | Thursday, February 22, 2007 |
| APPL NO | 11/710226 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/393 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593250 | Naumov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Alaska) |
| INVENTOR(S) | Ivan I. Naumov (Fayetteville, Arkansas); Laurent M. Bellaiche (Fayetteville, Arkansas); Sergey A. Prosandeev (Fayetteville, Arkansas); Inna V. Ponomareva (Fayetteville, Arkansas); Igor A. Kornev (Fayetteville, Arkansas) |
| ABSTRACT | A ferroelectric nanostructure formed as a low dimensional nano-scale ferroelectric material having at least one vortex ring of polarization generating an ordered toroid moment switchable between multi-stable states. A stress-free ferroelectric nanodot under open-circuit-like electrical boundary conditions maintains such a vortex structure for their local dipoles when subject to a transverse inhomogeneous static electric field controlling the direction of the macroscopic toroidal moment. Stress is also capable of controlling the vortex's chirality, because of the electromechanical coupling that exists in ferroelectric nanodots. |
| FILED | Friday, June 08, 2007 |
| APPL NO | 11/811444 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Static information storage and retrieval 365/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593758 | Foltyn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Stephen R. Foltyn (Los Alamos, New Mexico); Quanxi Jia (Los Alamos, New Mexico); Paul N. Arendt (Los Alamos, New Mexico); Terry G. Holesinger (Los Alamos, New Mexico); Haiyan Wang (Los Alamos, New Mexico) |
| ABSTRACT | A superconducting tape having reduced AC losses. The tape has a high temperature superconductor layer that is segmented. Disruptive strips, formed in one of the tape substrate, a buffer layer, and the superconducting layer create parallel discontinuities in the superconducting layer that separate the current-carrying elements of the superconducting layer into strips or filament-like structures. Segmentation of the current-carrying elements has the effect of reducing AC current losses. Methods of making such a superconducting tape and reducing AC losses in such tapes are also disclosed. |
| FILED | Thursday, October 06, 2005 |
| APPL NO | 11/245722 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07591883 | Kameoka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jun Kameoka (College Station, Texas); Keiyo Nakano (Aichi, Japan) |
| ABSTRACT | A nanofiber membrane is formed on a microfiber membrane. The nanofiber membrane may be electro sprayed directly onto the microfiber membrane and becomes integrated with the microfiber membrane to form a filter. The microfiber membrane provides structural integrity to for the nanofiber membrane, and an additional microfiber membrane may be added to sandwich the nanofiber membrane. |
| FILED | Friday, October 28, 2005 |
| APPL NO | 11/262550 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Gas separation: Processes 095/273 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07591897 | Sunkara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Mahendra Kumar Sunkara (Louisville, Kentucky); Sreeram Vaddiraju (Mountain View, California); Miran Mozetic (Ljubljan, Slovenia); Uros Cvelbar (Idrija, Slovenia) |
| ABSTRACT | A process for the rapid synthesis of metal oxide nanoparticles at low temperatures and methods which facilitate the fabrication of long metal oxide nanowires. The method is based on treatment of metals with oxygen plasma. Using oxygen plasma at low temperatures allows for rapid growth unlike other synthesis methods where nanomaterials take a long time to grow. Density of neutral oxygen atoms in plasma is a controlling factor for the yield of nanowires. The oxygen atom density window differs for different materials. By selecting the optimal oxygen atom density for various materials the yield can be maximized for nanowire synthesis of the metal. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/385015 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592008 | Sligar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois, a body corporate and politic of the State of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen G. Sligar (Urbana, Illinois); Timothy H. Bayburt (Urbana, Illinois); Mary A. Schuler (Urbana, Illinois); Natanya R. Civjan (Urbana, Illinois); Ylena V. Grinkova (Urbana, Illinois); Ilia G. Denisov (Urbana, Illinois); Stephen James Grimme (Urbana, Illinois) |
| ABSTRACT | The membrane scaffold proteins (MSP) of the present invention assemble with hydrophobic or partially hydrophobic proteins to form soluble nanoscale particles which preserve native structure and function; they are improved over liposomes and detergent micelles, in terms of stability and preservation of biological activity and native conformation. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles, which are robust in terms of integrity and maintenance of biological activity of incorporated proteins, facilitate pharmaceutical and biological research, structure/function correlations, structure determinations, bioseparations, and drug discovery. |
| FILED | Tuesday, January 11, 2005 |
| APPL NO | 11/033489 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592144 | Wood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | David W. Wood (Princeton, New Jersey); Georgios Skretas (Princeton, New Jersey) |
| ABSTRACT | The invention relates to fusion proteins and bacteria encoding them. The fusion proteins include a ligand-binding domain interposed between the splicing domains of an intein. An auxotroph-relieving protein domain is fused to one of the splicing domains so that the auxotroph-relieving function of the domain is activated upon ligand binding. The fusion proteins can be expressed in bacterial cells and used as sensors of binding of compounds with the ligand-binding domain of proteins such as the human estrogen receptors or the human thyroid hormone receptor. The bacterially expressed fusion proteins can detect and report agonist and antagonist activity characteristic of the naturally-occurring hormone with the ability to modulate the function of the protein from which the ligand-binding domain of the fusion protein is derived. |
| FILED | Thursday, March 17, 2005 |
| APPL NO | 11/082642 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592170 | Le Doux et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Joseph M. Le Doux (Decatur, Georgia); Martin L. Yarmush (Newton, Massachusetts); Jeffrey R. Morgan (Sharon, Massachusetts) |
| ABSTRACT | The invention provides new methods for purifying and concentrating viruses. The inventors have discovered that high molecular weight proteoglycans present in retroviral stocks are co-concentrated with the retroviruses, and can inhibit retroviral transduction. The new purification and concentration methods feature treatment of virus stock with an anionic polyelectrolyte and a cationic polyelectrolyte, followed by centrifugation. The new methods minimize the amount of proteoglycan co-precipitated with the infectious virus. |
| FILED | Tuesday, April 12, 2005 |
| APPL NO | 11/104161 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/239 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592254 | Abelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John R. Abelson (Urbana, Illinois); Sreenivas Jayaraman (Sunnyvale, California); Gregory S. Girolami (Urbana, Illinois); Yu Yang (Urbana, Illinois); Do Young Kim (Urbana, Illinois) |
| ABSTRACT | The present invention provides methods for conformally or superconformally coating and/or uniformly filling structures with a continuous, conformal layer or superconformal layer. Methods of the present invention improve conformal or superconformal coverage of surfaces and improve fill in recessed features compared to conventional physical deposition and chemical deposition methods, thereby minimizing formation of voids or gaps in a deposited conformal or superconformal layer. The present methods are capable of coating or filling features useful for the fabrication of a broad class of electronic, electrical and electromechanical devices. |
| FILED | Tuesday, October 31, 2006 |
| APPL NO | 11/554748 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/677 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592269 | Jacobs |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Heiko O. Jacobs (Minneapolis, Minnesota) |
| ABSTRACT | A method of forming a charge pattern includes treating a stamp layer with a plasma, applying the treated stamp layer to a surface of a substrate to thereby form a charge pattern on the surface of the substrate, and separating the stamp layer from the surface of the substrate. In one aspect, the method includes depositing nanoparticles on the surface of the substrate. An apparatus made in accordance with the method is also provided. |
| FILED | Tuesday, June 19, 2007 |
| APPL NO | 11/820473 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/763 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592504 | Klessig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Boyce Thompson Istitute for Plant Research, Inc. (Ithaca, New York) |
| INVENTOR(S) | Daniel F. Klessig (Dryden, New York); Dhirendra Kumar (Jonesborough, Tennessee) |
| ABSTRACT | Methods and kits for determining the specificity of siRNAs for their targets are provided. Also provided is a method for performing genetic analysis of the target protein or gene using different versions of a synthetic gene to complement the phenotype induced by RNAi-mediated silencing of the target protein and/or gene of interest. Finally, a method for treating genetic disorders associated with production of mutated proteins is also disclosed. |
| FILED | Wednesday, June 14, 2006 |
| APPL NO | 11/452821 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592506 | Grotewold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Erich Grotewold (Columbus, Ohio); Anusha P Dia (Columbus, Ohio); Edward L. Braun (Gainesville, Florida) |
| ABSTRACT | Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming a plant cell with an expression construct comprising a nucleic acid which encodes a transactivator protein comprising the myb domain of the maize “ZmMyb-IF35” protein and an activation domain. Another method comprises transforming a plant cell with an expression construct comprising a transgene which encodes an antisense ZmMyb-IF35 RNA. The present invention also relates to expression constructs and vectors used in the present methods, transformed plant cells and transgenic plants prepared according to the present methods, and the seeds of such transgenic plants. |
| FILED | Friday, December 22, 2006 |
| APPL NO | 11/615494 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/286 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593250 | Naumov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Alaska) |
| INVENTOR(S) | Ivan I. Naumov (Fayetteville, Arkansas); Laurent M. Bellaiche (Fayetteville, Arkansas); Sergey A. Prosandeev (Fayetteville, Arkansas); Inna V. Ponomareva (Fayetteville, Arkansas); Igor A. Kornev (Fayetteville, Arkansas) |
| ABSTRACT | A ferroelectric nanostructure formed as a low dimensional nano-scale ferroelectric material having at least one vortex ring of polarization generating an ordered toroid moment switchable between multi-stable states. A stress-free ferroelectric nanodot under open-circuit-like electrical boundary conditions maintains such a vortex structure for their local dipoles when subject to a transverse inhomogeneous static electric field controlling the direction of the macroscopic toroidal moment. Stress is also capable of controlling the vortex's chirality, because of the electromechanical coupling that exists in ferroelectric nanodots. |
| FILED | Friday, June 08, 2007 |
| APPL NO | 11/811444 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Static information storage and retrieval 365/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593776 | Loeb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Gerald E. Loeb (South Pasadena, California); Jack Weissberg (Culver City, California); Nuria Rodriguez (Los Angeles, California) |
| ABSTRACT | A novel system and method for restoring functional movement of a paralyzed limb(s) or a prosthetic device. Stimulating one or more muscles of a patient using an implanted neuromuscular implants and sensing the response of the stimulated muscle by the implants, wherein the sensing the response is not limited to data related to patient's movement intention, the posture, muscle extension, M-Wave and EMG. A communication and control protocol to operate the system safely and efficiently, use of forward and reverse telemetry channels having a limited bandwidth capacity, and minimizing the adverse consequences caused by errors in data transmission and intermittent loss of power to the implants. Adjusting stimulation rates and phases of the stimulator in order to achieve an efficient control of muscle force while minimizing fatigue and therefore providing for smooth movements and dynamic increase of the strength in patient's muscle contraction. |
| FILED | Tuesday, July 03, 2007 |
| APPL NO | 11/773322 |
| ART UNIT | 3766 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07591913 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Zhifeng Ren (Newton, Massachusetts); Gang Chen (Carlisle, Massachusetts); Shankar Kumar (Watertown, Massachusetts); Hohyun Lee (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally provides methods of improving thermoelectric properties of alloys by subjecting them to one or more high temperature annealing steps, performed at temperatures at which the alloys exhibit a mixed solid/liquid phase, followed by cooling steps. For example, in one aspect, such a method of the invention can include subjecting an alloy sample to a temperature that is sufficiently elevated to cause partial melting of at least some of the grains. The sample can then be cooled so as to solidify the melted grain portions such that each solidified grain portion exhibits an average chemical composition, characterized by a relative concentration of elements forming the alloy, that is different than that of the remainder of the grain. |
| FILED | Wednesday, April 06, 2005 |
| APPL NO | 11/100950 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Metal treatment 148/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592747 | Beach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert A. Beach (Altadena, California); Shouleh Nikzad (Valencia, California); Robert P. Strittmatter (Pasadena, California); Lloyd Douglas Bell (Sunland, California) |
| ABSTRACT | A photocathode, for generating electrons in response to incident photons in a photodetector, includes a base layer having a first lattice structure and an active layer having a second lattice structure and epitaxially formed on the base layer, the first and second lattice structures being sufficiently different to create a strain in the active layer with a corresponding piezoelectrically induced polarization field in the active layer, the active layer having a band gap energy corresponding to a desired photon energy. |
| FILED | Wednesday, February 09, 2005 |
| APPL NO | 11/056633 |
| ART UNIT | 2889 — Semiconductors/Memory |
| CURRENT CPC | Electric lamp and discharge devices 313/542 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07593763 | Lambert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Childrens Hospital Los Angeles (Los Angeles, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | James L. Lambert (Sunland, California); Mark S. Borchert (La Canada, California) |
| ABSTRACT | A non-invasive in vivo method for assessing macular carotenoids includes performing Optical Coherence Tomography (OCT) on a retina of a subject. A spatial representation of carotenoid levels in the macula based on data from the OCT of the retina can be generated. |
| FILED | Thursday, February 05, 2004 |
| APPL NO | 10/773099 |
| ART UNIT | 3768 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07591881 | Yeager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Artifex Equipment, Inc. (Penngrove, California); The United States of America as represented by the United States Department of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas G. Yeager (Penngrove, California); Kathleen C. Hayes (College Park, Maryland) |
| ABSTRACT | This invention provides novel devices and methods for manipulation of moisture/fluid levels in and/or upon objects and is used to, e.g., safely dry wet books and documents with minimal deleterious side effects or to add humidity to such books/documents or other objects or areas. |
| FILED | Thursday, September 29, 2005 |
| APPL NO | 11/241746 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Gas separation: Processes 095/117 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592506 | Grotewold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Erich Grotewold (Columbus, Ohio); Anusha P Dia (Columbus, Ohio); Edward L. Braun (Gainesville, Florida) |
| ABSTRACT | Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming a plant cell with an expression construct comprising a nucleic acid which encodes a transactivator protein comprising the myb domain of the maize “ZmMyb-IF35” protein and an activation domain. Another method comprises transforming a plant cell with an expression construct comprising a transgene which encodes an antisense ZmMyb-IF35 RNA. The present invention also relates to expression constructs and vectors used in the present methods, transformed plant cells and transgenic plants prepared according to the present methods, and the seeds of such transgenic plants. |
| FILED | Friday, December 22, 2006 |
| APPL NO | 11/615494 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/286 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07593289 | Schaefer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Phoenix Science and Technology, Inc. (Chelmsford, Massachusetts) |
| INVENTOR(S) | Raymond B. Schaefer (Lexington, Massachusetts); Michael Grapperhaus (Dracut, Massachusetts); John Gallagher (Goffstown, New Hampshire) |
| ABSTRACT | A reflector employs materials and design features that can transfer both light and sound emission simultaneously, from sources to planes or volumes, in an efficient and controlled manner. Compound orthogonal parabolic reflectors employ an extension onto conventional orthogonal parabolic reflectors to efficiently deliver light and/or sound to a focal volume or surface. The extension shapes the output, and can provide inflow and outflow to the focal region, along with a brush. Pulsed sources may be employed, which may emit light, sound or both light and sound, may erode and may be wire initiated with the wire replaced after each pulse by a wire feed. |
| FILED | Monday, April 17, 2006 |
| APPL NO | 11/379028 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/138 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 07592816 | Edwards |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Federal Aviation Administration (Washington, District of Columbia) |
| INVENTOR(S) | Steven William Edwards (Keller, Texas) |
| ABSTRACT | A Localizer cable fault analyzer that memorizes which antenna in a Localizer antenna array caused a fault. The Localizer equipment monitors the antenna transmit and monitor cables for continuity using a DC voltage. The present invention senses the voltage drop on the antenna circuit when a fault occurs and causes an indicator device to signal the presence of the fault in that particular antenna circuit. The indicator device continues to signal the presence of a fault until a reset switch is activated. |
| FILED | Tuesday, August 08, 2006 |
| APPL NO | 11/500331 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Measuring and testing 324/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 07593835 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Spectral Sciences, Inc. (Burlington, Massachusetts) |
| INVENTOR(S) | Gail P. Anderson (Boulder, Colorado); Alexander Berk (Canton, Massachusetts); Prabhat K. Acharya (Burlington, Massachusetts); Larry S. Bernstein (Lexington, Massachusetts); Steven M. Adler-Golden (Newtonville, Massachusetts); Jamine Lee (Burlington, Massachusetts); Leonid Muratov (Woburn, Massachusetts) |
| ABSTRACT | A radiative transport band model method for prediction and analysis of high spectral resolution radiometric measurements. Atomic and molecular line center absorption is determined from finite spectral bin equivalent widths. A mathematically exact expansion for finite bin equivalent widths provides high accuracy at any desired spectral resolution. The temperature and pressure dependent Voigt line tail spectral absorption contributing to each spectral bin is pre-computed and fit to Padé approximants for rapid and accurate accounting of neighboring-to-distant lines. A specific embodiment has been incorporated into the MODTRAN™ radiation transport model. |
| FILED | Wednesday, April 05, 2006 |
| APPL NO | 11/398696 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07591812 | Tamari |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yehuda Tamari (Oyster Bay, New York) |
| ABSTRACT | The invention is a closed complaint venous reservoir with at least one pliable wall having at least three innovative features: 1) the venous reservoir incorporates means that purge gas bubbles entering the venous reservoir without the user intervention, 2) the venous reservoir incorporates a cardiotomy reservoir, and 3) the pliable wall of the venous reservoir is sealed within a rigid housing allowing control of its “atmospheric” pressure, and therefore the pressure at which that wall collapses. The combination of the three innovative features provides a collapsible compliant reservoir unitized with cardiotomy reservoir having air removal features and enabling vacuum augmented venous drainage (VAVD) that match that of the open hardshell venous-cardiotomy reservoir unit, while retaining the advantages of the closed soft shell venous reservoir. |
| FILED | Monday, July 24, 2006 |
| APPL NO | 11/491853 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/406 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07592008 | Sligar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois, a body corporate and politic of the State of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen G. Sligar (Urbana, Illinois); Timothy H. Bayburt (Urbana, Illinois); Mary A. Schuler (Urbana, Illinois); Natanya R. Civjan (Urbana, Illinois); Ylena V. Grinkova (Urbana, Illinois); Ilia G. Denisov (Urbana, Illinois); Stephen James Grimme (Urbana, Illinois) |
| ABSTRACT | The membrane scaffold proteins (MSP) of the present invention assemble with hydrophobic or partially hydrophobic proteins to form soluble nanoscale particles which preserve native structure and function; they are improved over liposomes and detergent micelles, in terms of stability and preservation of biological activity and native conformation. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles, which are robust in terms of integrity and maintenance of biological activity of incorporated proteins, facilitate pharmaceutical and biological research, structure/function correlations, structure determinations, bioseparations, and drug discovery. |
| FILED | Tuesday, January 11, 2005 |
| APPL NO | 11/033489 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07592321 | Whitley et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chester B. Whitley (Brooklyn Park, Minnesota); R. Scott McIvor (St. Louis Park, Minnesota) |
| ABSTRACT | Isolated nucleic acid-based vectors and lentivirus vectors, and methods of using those vectors to inhibit or prevent metabolic disorders in a mammal, are provided. |
| FILED | Monday, February 14, 2005 |
| APPL NO | 11/057410 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07592953 | Morana |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Comtech Mobile Datacom Corporation (Germantown, Maryland) |
| INVENTOR(S) | Sebastian Morana (Aldie, Virginia) |
| ABSTRACT | Provided is a mobile satellite transceiver system for communicating with a Global Positioning System (GPS) satellite and a communications satellite. In on implementation, the mobile satellite transceiver system includes a GPS receiver configured to receive communications from the GPS satellite, a satellite modem configured to transmit and receive communications from the communications satellite, and an operating system. In some implementations, the operating system of the mobile satellite transceiver system is configured to send and receive text messages to/from the communications satellite via the satellite modem. In some implementations the mobile satellite transceiver system also includes a Radio Frequency Identification (RFID) interrogator for communicating with RFID tags. |
| FILED | Friday, December 29, 2006 |
| APPL NO | 11/618379 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/357.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 22, 2009.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2009/fedinvent-patents-20090922.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page