FedInvent™ Patents

Patent Details for Tuesday, October 06, 2009 

This page was updated on Monday, March 27, 2023 at 01:27 AM GMT

Department of Defense (DOD) 

US 07596950 Woltmann et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ivan Elmer Woltmann (West Chester, Ohio);  Thurmond Douglas Senter (Mason, Ohio);  Lawrence Paul Timko (Fairfield, Ohio)
ABSTRACT A gas turbine engine augmentor radial fuel spray bar has a counterswirling spray bar heat shield. Two embodiments of the heat shield include one with a cambered airfoil cross-section and another with a twisted airfoil cross-section and may have varying or constant degree of camber or twist, respectively, along a radial length of the spray bar heat shield. The spray bar may have one or more spray bar fuel tubes within the heat shield, openings in the heat shield, and fuel holes in the tubes operable for injecting fuel through the openings. A gas turbine engine augmentor having a plurality of circumferentially spaced apart radial flameholders may incorporate a plurality of the augmentor radial fuel spray bars with one or more of the augmentor radial fuel spray bars circumferentially disposed between one or more circumferentially adjacent pairs of the radial flameholders.
FILED Friday, September 16, 2005
APPL NO 11/228793
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/765
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597010 Clark et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Arthur E. Clark (Adelphi, Maryland);  Marilyn Wun-Fogle (Potomac, Maryland);  James B. Restorff (College Park, Maryland)
ABSTRACT A method of using a magnetostrictive material to achieve a high magnetomechanical coupling factor comprising building an internal anisotropy energy into the magnetostrictive material and applying a tensile or compressive stress to the magnetostrictive material with the built-in internal anisotropy energy. The internal anisotropy energy is built into the magnetostrictive material by annealing the magnetostrictive material under an annealing stress or a suitable magnetic field. For a positive magnetostrictive material, when the annealing stress is compressive, the stress applied to the annealed material under operation is tensile, and when the annealing stress is the tensile, the stress applied to the annealed material under operation is compressive. For a negative magnetostrictive material, when the annealing stress is compressive, the stress applied to the annealed material under operation is tensile, and when the annealing stress is tensile, the stress applied to the annealed material under operation is compressive.
FILED Tuesday, November 15, 2005
APPL NO 11/274635
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/862.335
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597038 Travis
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Matt H. Travis (Fall City, Washington)
ABSTRACT An exemplary stores launch tube includes an outer tube and an inner tube. The inner tube is disposed interior the outer tube and is configured to reduce load as a store exits therefrom. The inner tube may be made of a flexible material. At least one load-reducing device may be disposed between the inner tube and the outer tube. The inner tube may be received within a canister that has an outer casing that is attachable to the outer tube. Alternately, the inner tube may be attached directly to the outer tube. The inner tube may include more than one tube section. If desired, filler material, such as foam, may be disposed between the inner tube and the outer tube. The outer tube may have a substantially circular cross-section, or an oval cross-section, or any cross-section as desired to accommodate structural considerations.
FILED Wednesday, January 31, 2007
APPL NO 11/701304
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/1.510
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597046 Laib
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gerald Laib (Olney, Maryland)
ABSTRACT A method of making a thin film explosive detonator includes forming a substrate layer; depositing a metal layer in situ on the substrate layer; and reacting the metal layer to form a primary explosive layer. The method and apparatus formed thereby integrates fabrication of a micro-detonator in a monolithic MEMS structure using “in-situ” production of the explosive material within the apparatus, in sizes with linear dimensions below about 1 mm. The method is applicable to high-volume low-cost manufacturing of MEMS safety-and-arming devices. The apparatus can be initiated either electrically or mechanically at either a single point or multiple points, using energies of less than about 1 mJ.
FILED Wednesday, December 03, 2003
APPL NO 10/729266
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Ammunition and explosives
12/202.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597047 Doyle et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Warfare Center (NAWC)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts);  Pacific Coast Systems LLC (Asbury, New Jersey)
INVENTOR(S) Thomas Doyle (Helendale, California);  Diana P. Schaeffer (Denville, New Jersey)
ABSTRACT According to one embodiment, a system for simulating an actual explosion of an explosive device includes one or more firing devices and a control module. A firing device comprises a pyrotechnic device operable to direct a pyrotechnic explosion in a predetermined direction to simulate the actual explosion of the explosive device. The control module receives a trigger signal from a trigger device, which is operable to send the trigger signal in response to a trigger event. The control module detonates the firing devices in response to the trigger signal.
FILED Friday, June 30, 2006
APPL NO 11/427855
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/355
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597162 Won
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) iRobot Corporation (Bedford, Massachusetts)
INVENTOR(S) Chikyung Won (Somerville, Massachusetts)
ABSTRACT An articulated tracked vehicle that has a main section, which includes a main frame, and a forward section. The main frame has two sides and a front end, and includes a pair of parallel main tracks. Each main track includes a flexible continuous belt coupled to a corresponding side of the main frame. The forward section includes an elongated arm. One end of the arm is pivotally coupled to the main frame near the forward end of the main frame about a transverse axis that is generally perpendicular to the sides of the main frame. The arm has a length sufficiently long to allow the forward section to extend below the main section in at least some degrees of rotation of the arm, and a length shorter than the length of the main section. The center of mass of the main section is located forward of the rearmost point reached by the end of the arm in its pivoting about the transverse axis. The main section is contained within the volume defined by the main tracks and is symmetrical about a horizontal plane, thereby allowing inverted operation of the robot.
FILED Wednesday, December 24, 2003
APPL NO 10/745941
ART UNIT 3611 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Motor vehicles
180/9.320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597692 Weaver et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) James C. Weaver (Sudbury, Massachusetts);  R. Rox Anderson (Lexington, Massachusetts);  Terry O. Herndon (Carlisle, Massachusetts)
ABSTRACT The present invention relates to microscission methods and devices used for the manipulation or modification of the body tissue by the formation of microconduits in a tissue. The term “microconduit” refers to a small opening, channel, or hole into, or through, a tissue, that allows transfer of materials by liquid flow, and by electrophoresis, the microconduit being formed upon impact of a plurality of accelerated microparticles with the surface of the tissue. This process of “microscission” comprises forming at least one microconduit in tissue including the steps of: accelerating a plurality of microparticles to a velocity that causes the microparticles to penetrate a region of tissue surface upon impingement of the microparticles on the tissue surface; and directing the microparticle towards the region of tissue surface, thereby causing the microparticles to penetrate the tissue and form a microconduit in the tissue.
FILED Monday, March 15, 2004
APPL NO 10/800587
ART UNIT 3767 — Optics
CURRENT CPC
Surgery
64/500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597717 Lu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ryan P. Lu (Carlsbad, California);  Stephen D. Russell (San Diego, California);  Ayax D. Ramirez (Chula Vista, California)
ABSTRACT A scanning probe microscopy head may include a base portion, cantilevers coupled to the base portion, and at least one tip coupled to each of the cantilevers. At least two of the cantilevers and associated tips may be configured to perform a different scanning probe microscopy technique. The cantilevers may be positioned perpendicular to the base portion and may be coupled to the perimeter of the base portion. The base portion may include circuitry coupled thereto for providing electricity to the tips. The cantilevers may each be placed into a recessed slot along the perimeter of the base and secured to the base by a securing mechanism, such as a spring clip. The cantilevers may be operatively coupled to a linear positioner, such as a piezoelectric motor, coupled to the perimeter of the base for controlling the amount of protrusion of the cantilevers from the perimeter of the base.
FILED Monday, June 25, 2007
APPL NO 11/767713
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/22
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US 07597791 Huang et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Lotien Richard Huang (Brookline, Massachusetts);  James Christopher Sturm (Princeton, New Jersey);  Robert Hamilton Austin (Princeton, New Jersey)
ABSTRACT A method and apparatus for generating tunable, uniform electric fields in fluidic applications for rapid separation of molecules, such as DNA, is provided. A region receives the molecules to be separated, the molecules being injected into the region by an injection channel connected thereto. Fluidic microchannels or resistor arrays connected to sides of the region inject currents into the region and produce electric fields in the region that can be oriented at any angle. The electric fields can separate the molecules according to size, and can be used to move or manipulate the molecules within the region. Further, the molecules can be separated by controlling fluid flows within the region to manipulate the molecules. One or more reservoirs can be attached to the fluidic microchannels for collecting the molecules after separation, movement, or manipulation.
FILED Wednesday, May 15, 2002
APPL NO 10/147370
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical and wave energy
24/600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597838 Subramanian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Suresh Subramanian (Mason, Ohio);  James Dale Steibel (Mason, Ohio);  Douglas Melton Carper (Trenton, Ohio);  Toby George Darkins, Jr. (Loveland, Ohio)
ABSTRACT A ceramic matrix composite with a ceramic matrix and a gradient layering of coating on ceramic fibers. The coating typically improves the performance of the composite in one direction while degrading it in another direction. For a SiC-SiC ceramic matrix composite, a BN coating is layered in a gradient fashion or in a step-wise fashion in different regions of the article comprising the ceramic. The BN coating thickness is applied over the ceramic fibers to produce varying desired physical properties by varying the coating thickness within differing regions of the composite, thereby tailoring the strength of the composite in the different regions. The coating may be applied as a single layer as a multi-layer coating to enhance the performance of the coating as the ceramic matrix is formed or infiltrated from precursor materials into a preform of the ceramic fibers.
FILED Thursday, December 30, 2004
APPL NO 11/027403
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/640
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597867 Santiago et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Francisco Santiago (Fredericksburg, Virginia);  Victor H. Gehman, Jr. (Dahlgren, Virginia);  Karen J. Long (Upper Marlboro, Maryland);  Kevin A. Boulais (Waldorf, Maryland)
ABSTRACT Carbon nanotube apparatus, and methods of carbon nanotube modification, include carbon nanotubes having locally modified properties with the positioning of the modifications being controlled. More specifically, the positioning of nanotubes on a substrate with a deposited substance, and partially vaporizing part of the deposited substance etches the nanotubes. The modifications of the carbon nanotubes determine the electrical properties of the apparatus and applications such as a transistor or Shockley diode. Other applications of the above mentioned apparatus include a nanolaboratory that assists in study of merged quantum states between nanosystems and a macroscopic host system.
FILED Tuesday, July 31, 2007
APPL NO 11/894640
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/414
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597890 Chinnaiyan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Arul Chinnaiyan (Plymouth, Michigan);  David Beer (Chelsea, Michigan);  Guoan Chen (Ann Arbor, Michigan);  Xiaoju Wang (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
FILED Thursday, March 08, 2007
APPL NO 11/715642
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/133.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597934 Nagaraj et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Bangalore A. Nagaraj (West Chester, Ohio);  Mark D. Gorman (Cincinnati, Ohio)
ABSTRACT A method for making a gas turbine engine turbine blade comprising an airfoil section a platform section, an under platform section, and a dovetail section, the exterior surface of the dovetail section comprising a shank exterior surface and a serrated exterior surface. The blade further includes a silicon-modified diffusion aluminide layer a surface of a turbine blade section selected from the group consisting of the exterior surface of the under platform section, the exterior surface of the dovetail section, and combinations thereof, the aluminide layer having a concentration of silicon at a surface of the aluminide layer in the range of about 1 weight percent to about 10 weight percent and a concentration of aluminum at the surface of the aluminide layer in the range of about 5 weight percent to about 25 weight percent.
FILED Tuesday, February 21, 2006
APPL NO 11/358339
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/397.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597966 Spitsberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Irene Spitsberg (Loveland, Ohio);  Brett Allen Rohrer Boutwell (Liberty Township, Ohio);  Robert William Bruce (Loveland, Ohio);  Curtis Alan Johnson (Niskayuna, New York);  Bangalore Aswatha Nagaraj (West Chester, Ohio);  William Scott Walston (Cincinnati, Ohio)
ABSTRACT A thermal barrier coating and deposition process for a component intended for use in a hostile thermal environment, such as the turbine, combustor and augmentor components of a gas turbine engine. The TBC has a first coating portion on at least a first surface portion of the component. The first coating portion is formed of a ceramic material to have at least an inner region, at least an outer region overlying the inner region, and a columnar microstructure whereby the inner and outer regions comprise columns of the ceramic material. The columns of the inner region are more closely spaced than the columns of the outer region so that the inner region of the first coating portion is denser than the outer region of the first coating portion, wherein the higher density of the inner region promotes the impact resistance of the first coating portion.
FILED Friday, June 10, 2005
APPL NO 11/160164
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Stock material or miscellaneous articles
428/469
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598000 Chan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Yuk Chan (Eatontown, New Jersey);  Terrill B. Atwater (North Plainfield, New Jersey)
ABSTRACT An anode for a metal-air battery has an electrode and a metal foil interconnected with the electrode. A barrier layer surrounds the metal foil and includes a polymer blend that substantially reduces the passage of moisture therethrough while permitting the passage of ions therethrough. A method of making the barrier layer is also presented.
FILED Wednesday, January 05, 2005
APPL NO 11/031949
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/231.950
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598341 Hanahan et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Burnham Institue for Medical Research (La Jolla, California);  The Regents of the Universtiy of California (Oakland, California)
INVENTOR(S) Douglas Hanahan (San Francisco, California);  Erkki Ruoslahti (Rancho Santa Fe, California);  Johanna A. Joyce (New York, New York);  Pirjo Laakkonen (Helsinki, Finland)
ABSTRACT The invention provides a conjugate that includes a therapeutic moiety linked to a peptide or peptidomimetic that selectively homes to vasculature of premalignant pancreas. The peptide or peptidomimetic contains at least 5 contiguous amino acids of an amino acid sequence selected from CRSRKG (SEQ ID NO:9) and CEYQLDVE (SEQ ID NO:34), or a conservative variant or peptidomimetic thereof. The invention additionally provides a conjugate containing a therapeutic moiety linked to a peptide or peptidomimetic that selectively homes to pancreatic tumor cells and pancreatic tumor vasculature, the peptide or peptidomimetic comprising at least 5 contiguous amino acids of an amino acid sequence selected from CKAAKNK (SEQ ID NO:15), CKGAKAR (SEQ ID NO:19), and VGVGEWSV (SEQ ID NO:35), or a conservative variant or peptidomimetic thereof.
FILED Friday, October 29, 2004
APPL NO 10/977367
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
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US 07598342 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Albany Medical College (Albany, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  James A. Bennett (Delmar, New York);  Herbert Jacobson (Albany, New York);  George C. Shields (Clinton, New York);  Karl N. Kirschner (Clinton, New York)
ABSTRACT The invention relates to compounds that include peptide and peptidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
FILED Monday, February 26, 2007
APPL NO 11/678784
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598352 Koide
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Shohei Koide (Rochester, New York)
ABSTRACT A method of identifying a polypeptide monobody having target protein binding activity, said method comprising: providing a host cell comprising (i) a reporter gene under control of a 5′ regulatory region operable in the host cell, (ii) a first chimeric gene which encodes a first fusion polypeptide comprising a target protein, or fragment thereof, fused to a C-terminus of a DNA-binding domain which binds to the 5′ regulatory region of the reporter gene, and (iii) a second chimeric gene which encodes a second fusion polypeptide comprising a polypeptide monobody fused to a transcriptional activation domain; and detecting expression of the reporter gene, which indicates binding of the polypeptide monobody of the second fusion polypeptide to the target protein such that the transcriptional activation domain of the second fusion polypeptide is in sufficient proximity to the DNA-binding domain of the first fusion polypeptide to allow expression of the reporter gene.
FILED Monday, November 19, 2001
APPL NO 10/006760
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598363 Seeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Nadrian C. Seeman (New York, New York);  Baoquan Ding (New York, New York);  Pamela E. Constantinou (New York, New York);  Tong Wang (Brooklyn, New York);  Jens Kopatsch (Brooklyn, New York);  Xiaoping Zhang (Woodside, New York);  Ruojie Sha (Pomona, New York);  Lisa Israel (New York, New York)
ABSTRACT Robust nucleic acid arrays and lattices are assembled based on double crossover cohesion of polygonal units whose edges are composed of nucleic acid multi-crossover domains.
FILED Thursday, June 09, 2005
APPL NO 11/148423
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598381 Thompson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey);  The University of Southern California (Los Angeles, California);  The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Mark E. Thompson (Anaheim, California);  Carsten Borek (Pasadena, California);  Kenneth Hanson (Los Angeles, California);  Peter Djurovich (Long Beach, California);  Yiru Sun (Princeton, New Jersey);  Stephen Forrest (Ann Arbor, Michigan);  Arnold Tamayo (Glendale, California)
ABSTRACT Certain iridium compounds which may comprise an iridium(III)-ligand complex having the general formula: (C^N)2—Ir—(N^N). (C^N) and (N^N) may each represent a ligand coordinated to an iridium atom. The iridium compounds may have a primary phosphorescent photoluminescence peak wavelength in the near-infrared (IR) range. Also, organic devices that use certain iridium compounds. The organic device may comprise an organic layer and the organic layer may comprise any of the iridium compounds disclosed herein. Also, organic devices that use certain metalloporphyrin compounds. The metalloporphyrin compounds may comprise a core porphyrin structure with four pyrrole rings. The metalloporphyrin compounds may have a primary phosphorescent photoluminescence peak wavelength in the near-IR range.
FILED Monday, September 11, 2006
APPL NO 11/518311
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598513 Kouvetakis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents, Acting for and on behalf of Arizona State University, A Corporate Body Organized under Arizona Law (, None)
INVENTOR(S) John Kouvetakis (Mesa, Arizona);  Matthew Bauer (Hillsboro, Oregon);  John Tolle (Gilbert, Arizona)
ABSTRACT A novel method for synthesizing device-quality alloys and ordered phases in a Si—Ge—Sn system uses a UHV-CVD process and reactions of SnD4 with SiH3GeH3. Using the method, single-phase SixSnyGe1-x-y semiconductors (x≦0.25, y≦0.11) are grown on Si via Ge1-xSnx buffer layers The Ge1-xSnx buffer layers facilitate heteroepitaxial growth of the SixSnyGe1-x-y films and act as compliant templates that can conform structurally and absorb the differential strain imposed by the more rigid Si and Si—Ge—Sn materials. The SiH3GeH3 species was prepared using a new and high yield method that provided high purity semiconductor grade material.
FILED Monday, June 14, 2004
APPL NO 10/559979
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598514 Freedman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Microsoft Corporation (Redmond, Washington)
INVENTOR(S) Michael H. Freedman (Redmond, Washington);  Chetan V. Nayak (Santa Monica, California);  Sankar Das Sarma (Potomac, Maryland)
ABSTRACT A quantum computer can only function stably if it can execute gates with extreme accuracy. “Topological protection” is a road to such accuracies. Quasi-particle interferometry is a tool for constructing topologically protected gates. Assuming the corrections of the Moore-Read Model for ν=5/2's FQHE (Nucl. Phys. B 360, 362 (1991)) we show how to manipulate the collective state of two e/4-charge anti-dots in order to switch said collective state from one carrying trivial SU(2) charge, |1>, to one carrying a fermionic SU(2) charge |ε>. This is a NOT gate on the {|1>, |ε>} qubit and is effected by braiding of an electrically charged quasi particle σ which carries an additional SU(2)-charge. Read-out is accomplished by σ-particle interferometry.
FILED Wednesday, May 28, 2008
APPL NO 12/128417
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598555 Papworth Parkin
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Stuart Stephen Papworth Parkin (San Jose, California)
ABSTRACT MgO tunnel barriers are formed by depositing a thin layer of Mg on a suitable underlayer, and then directing oxygen and additional Mg towards the Mg layer. The oxygen reacts with the additional Mg and the Mg in the Mg layer to form a MgO tunnel barrier that enjoys excellent tunneling characteristics. The MgO tunnel barriers so formed may be used in magnetic tunnel junctions having tunneling magnetoresistance (TMR) values of greater than 100%. The highest TMR values are observed for junctions that have been annealed and that have a (100) crystallographic orientation.
FILED Monday, October 25, 2004
APPL NO 10/973954
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598567 Hefner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Allen Hefner (Darnestown, Maryland);  Sei-Hyung Ryu (Cary, North Carolina);  Anant Agarwal (Chapel Hill, North Carolina)
ABSTRACT A semiconductor device includes a drift layer having a first conductivity type and a body region adjacent the drift layer. The body region has a second conductivity type opposite the first conductivity type and forms a p-n junction with the drift layer. The device further includes a contactor region in the body region and having the first conductivity type, and a shunt channel region extending through the body region from the contactor region to the drift layer. The shunt channel region has the first conductivity type. The device further includes a first terminal in electrical contact with the body region and the contactor region, and a second terminal in electrical contact with the drift layer. The shunt channel region has a length, thickness and doping concentration selected such that: 1) the shunt channel region is fully depleted when zero voltage is applied across the first and second terminals, 2) the shunt channel becomes conductive at a voltages less than the built-in potential of the drift layer to body region p-n junction, and/or 3) the shunt channel is not conductive for voltages that reverse biase the p-n junction between the drift region and the body region.
FILED Friday, November 03, 2006
APPL NO 11/556448
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/328
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598582 Boisvert et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Joseph Charles Boisvert (Thousand Oaks, California);  Takahiro D. Isshiki (Pasadena, California);  Rengarajan Sudharsanan (Stevenson Ranch, California)
ABSTRACT A photodetector and a method for fabricating a photodetector. The photodetector may include a substrate, a buffer layer formed on the substrate, and an absorption layer formed on the buffer layer for receiving incident photons and generating charged carriers. An N-doped interface layer may be formed on the absorption layer, an N-doped cap layer may be formed on the N-doped interface layer, and a dielectric passivation layer may be formed above the cap layer. A P+ diffusion region may be formed within the cap layer, the N-doped interface layer and at least a portion of the absorption layer, and at least one contact may be formed on and coupled to the P+ diffusion region.
FILED Wednesday, June 13, 2007
APPL NO 11/762489
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/436
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598651 Kornbluh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Roy D. Kornbluh (Palo Alto, California);  Ronald E. Pelrine (Louisville, Colorado);  Harsha Prahlad (Cupertino, California);  Scott E. Stanford (Mountain View, California)
ABSTRACT The present invention provides meta-materials with an actively controllable mechanical property. The meta-material includes a deformable structure and a set of activation elements. The activation elements are controllable between multiple states. The meta-material includes a first value for a mechanical property when one or more of the activation elements is in the first activation state and includes a second value for the mechanical property when the activation elements have been activated to the second activation state. In one aspect, the meta-material resembles a composite material where the connectivity between the component materials or shape and arrangement of the component materials is dynamically controllable so as to affect a mechanical property of the meta-material.
FILED Friday, March 11, 2005
APPL NO 11/078678
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598652 Kornbluh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Roy D. Kornbluh (Palo Alto, California);  Ronald E. Pelrine (Longmont, Colorado);  Harsha Prahlad (Cupertino, California);  Scott E. Stanford (Mountain View, California)
ABSTRACT The present invention provides meta-materials with an actively controllable mechanical property. The meta-material includes a deformable structure and a set of activation elements. The activation elements are controllable between multiple states. The meta-material includes a first value for a mechanical property when one or more of the activation elements is in the first activation state and includes a second value for the mechanical property when the activation elements have been activated to the second activation state. In one aspect, the meta-material resembles a composite material where the connectivity between the component materials or shape and arrangement of the component materials is dynamically controllable so as to affect a mechanical property of the meta-material.
FILED Monday, July 30, 2007
APPL NO 11/830806
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598850 Manz
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Paul C. Manz (Matawan, New Jersey)
ABSTRACT An information system, method, and computer program product is provided for the centralized warning of existing or developing significant events and/or threats to affected users carrying a user warning and positioning device, while reporting the location of all user's carrying the user warning and positioning devices of the system to existing command and control systems. The present invention's future event warning capabilities permit those same affected users to be warned of impending events in enough time for the users to take positive actions in response to these events and/or address those events. The system of the present invention includes a pager-like user warning and positioning device, worn by or carried by the individual user, or mounted in a vehicle or vessel, having a geographical positioning means therein, which periodically transmits the geographical location of the individual user, vehicle or vessel, and listens for warning/notification event messages transmitted by a network bridge or situational awareness workstation and threat warning gateway (central processing means). When an event/threat warning is received by the user warning and positioning device, the pager-like user warning and positioning device alerts the user via indicia relative to the event/situation, including audible spoken warnings and instructions on how to react, and may retransmit the event/threat warning to other user warning and positioning devices in the network, provided the threat has not occurred and the event/threat warning has not been previously relayed.
FILED Wednesday, July 12, 2006
APPL NO 11/489800
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/506
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598897 Kirichenko
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Communications-Electronics Research, Development and Engineering Center (CERDEC)
Department of the Navy (DON)
Office of Naval Research (ONR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) HYPRES, Inc. (Elmsford, New York)
INVENTOR(S) Dmitri Kirichenko (Pleasantville, New York)
ABSTRACT A superconducting Analog-to-Digital Converter (ADC) employing rapid-single-flux-quantum (RSFQ) logic is disclosed. The ADC has only superconductor active components, and is characterized as being an Nth-order bandpass sigma-delta ADC, with the order “N” being at least 2. The ADC includes a sequence of stages, which stages include feedback loops and resonators. The ADC further includes active superconducting components which directionally couple resonator pairs of adjacent stages. The active superconducting components electrically shield the higher order resonator from the lower order resonator. These active superconductor components include a superconducting quantum interference device (SQUID) amplifier, which is inductively coupled to the higher order resonator, and may include a Josephson transmission line (JTL), which is configured to electrically connect the SQUID amplifier to the lower order resonator. The first stage of ADC may employ an implicit feedback loop.
FILED Thursday, December 13, 2007
APPL NO 11/955666
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599165 Hampden-Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Cabot Corporation (Boston, Massachusetts)
INVENTOR(S) Mark J. Hampden-Smith (Albuquerque, New Mexico);  Toivo T. Kodas (Albuquerque, New Mexico);  Quint H. Powell (Albuquerque, New Mexico);  Daniel J. Skamser (Albuquerque, New Mexico);  James Caruso (Albuquerque, New Mexico);  Clive D. Chandler (Portland, Oregon)
ABSTRACT Provided are palladium-containing powders and a method and apparatus for manufacturing the palladium-containing particles of high quality, of a small size and narrow size distribution. An aerosol is generated from liquid feed and sent to a furnace, where liquid in droplets in the aerosol is vaporized to permit formation of the desired particles, which are then collected in a particle collector. The aerosol generation involves preparation of a high quality aerosol, with a narrow droplet size distribution, with close control over droplet size and with a high droplet loading suitable for commercial applications. Powders may have high resistance to oxidation of palladium. Multi-phase particles are provided including a palladium-containing metallic phase and a second phase that is dielectric. Electronic components are provided manufacturable using the powders.
FILED Tuesday, February 06, 2007
APPL NO 11/671969
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/306.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599248 Williams
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Earl G Williams (Fairfax, Virginia)
ABSTRACT A system and method for determining vector acoustic intensity fields using a spherical array of acoustic sensors, and a regularization technique. A mobile spherical array of a number of microphones that image the acoustic intensity vector throughout a large volume internal and external to the spherical array.
FILED Tuesday, December 18, 2007
APPL NO 11/959454
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/8
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599253 Huang
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Dehua Huang (Newport, Rhode Island)
ABSTRACT The invention as disclosed is of a combined acoustic pressure and acoustic vector sensor array, where multiple acoustic pressure sensors are integrated with an acoustic vector sensor in a towed array as a means of resolving the left-right ambiguity of the multiple acoustic pressure sensors.
FILED Thursday, July 24, 2008
APPL NO 12/221149
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599524 Camus et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Sarnoff Corporation (Princeton, New Jersey)
INVENTOR(S) Theodore A. Camus (Mount Laurel, New Jersey);  Richard Wildes (Toronto, Canada)
ABSTRACT A method of quickly and robustly localizing a pair of concentric circular region boundaries in a digital image, such as the pupil and iris boundaries in an image of a human eye is disclosed. Specularities in the image are optionally filled. An object containing concentric regions, e.g., a pupil and iris, is found within the image.
FILED Monday, April 05, 2004
APPL NO 10/818307
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/117
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599876 Lo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Aeronautical Systems Center (ASC)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Advanced Simulation and Computing Program (ASC)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Andrew Lo (Lexington, Massachusetts);  Tung Chan (Cambridge, Massachusetts);  Tomaso Poggio (Wellesley, Massachusetts)
ABSTRACT Disclosed herein is an automated Electronic Market-Maker, comprising a Market Quality Control Module for generating trading recommendations to maintain market quality; an Inventory Control Module for generating trading recommendations to maintain inventory; a Speculation Module for generating trading recommendations to generate profits; and an Arbitration Module to receive trading recommendations from said Market Quality Control Module, Inventory Control Module, and Speculation Control Module and resolve any conflicts between the received recommendations.
FILED Wednesday, March 15, 2000
APPL NO 09/526633
ART UNIT 3692 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599896 Peters, II
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Richard Alan Peters, II (Nashville, Tennessee)
ABSTRACT An architecture for robot intelligence enables a robot to learn new behaviors and create new behavior sequences autonomously and interact with a dynamically changing environment. Sensory information is mapped onto a Sensory Ego-Sphere (SES) that rapidly identifies important changes in the environment and functions much like short term memory. Behaviors are stored in a DBAM that creates an active map from the robot's current state to a goal state and functions much like long term memory. A dream state converts recent activities stored in the SES and creates or modifies behaviors in the DBAM.
FILED Monday, February 04, 2008
APPL NO 12/025540
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/14
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07597890 Chinnaiyan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Arul Chinnaiyan (Plymouth, Michigan);  David Beer (Chelsea, Michigan);  Guoan Chen (Ann Arbor, Michigan);  Xiaoju Wang (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
FILED Thursday, March 08, 2007
APPL NO 11/715642
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/133.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597907 Muzykantov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Vladimir R. Muzykantov (Warwick, Pennsylvania);  Tom Dziubla (Lansdale, Pennsylvania)
ABSTRACT The present invention is a method for encapsulating active protein in a polymeric nanocarrier. The instant method employs homogenization at subzero temperatures so that enzyme activity is retained. Enzymes which can be encapsulated by the present method include, for example, antioxidant enzymes and xenobiotic detoxifying enzymes. Encapsulation of an enzyme protects it from protease degradation and increases therapeutic half-life. Advantageously, polymeric nanoparticles of the invention are permeable to enzyme substrates and therefore enzymes encapsulated by the instant method can exert their effect without release from the nanocarrier. Methods for decomposing a reactive oxygen species, protecting against vascular oxidative stress, and detoxifying a xenobiotic are also provided.
FILED Friday, November 04, 2005
APPL NO 11/266785
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/490
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598028 Macoska
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Jill A. Macoska (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for the detecting, treating, and empirically investigating cellular proliferation disorders and cellular motility disorders. In particular, the present invention provides compositions and methods for using CXCL chemokines (e.g., CXCL1, CXCL5, CXCL6, CXCL12), CXCL receptors (e.g., CXCR1, CXCR2, CXCR4, CXCR7), and/or pathway related compounds (e.g., NF-kappaB, ERK ½, ELK-1) in the diagnosis, treatment, and empirical investigation of prostate disorders (e.g., prostate cancer, benign prostatic hypertrophy, prostatitis).
FILED Wednesday, November 28, 2007
APPL NO 11/946676
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598042 Getzenberg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Robert H. Getzenberg (Pittsburgh, Pennsylvania)
ABSTRACT A novel prostate cancer marker is described that is found in cancerous and normal prostate cells of individuals that have prostate cancer but is not found in the prostate of individuals without prostate cancer. The marker also is present in normal tissue adjacent to tumor tissue in individuals having prostate cancer. The marker, however, is absent in the prostate of individuals without prostate cancer. Methods employing the novel prostate cancer marker of the invention to predict the occurrence of the prostate disease, monitor the progression of prostate cancer and effect the treatment of prostate cancer, also are described.
FILED Monday, March 01, 2004
APPL NO 10/514735
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598043 Lyden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) David Lyden (New York, New York);  Rosandra N. Kaplan (New York, New York);  Rebecca D. Riba (New York, New York);  Shahin Rafii (Great Neck, New York)
ABSTRACT The present invention is directed to a method of inhibiting tumor formation in a cancer patient at a site remote from sites of prior tumor formation and to a method of preventing metastases. These methods involve administering to the cancer patient an inhibitor of vascular endothelial growth factor receptor 1+ bone marrow-derived cells under conditions effective either to inhibit tumor formation in the cancer patient at a site remote from sites of prior tumor formation or to prevent metastases. Candidate compounds useful for such purposes can be screened depending on whether they bind to vascular endothelial growth factor receptor 1+ bone marrow-derived cells. Metastases in a cancer patient can be monitored by evaluating a patient sample for detection and quantification of vascular endothelial growth factor receptor 1+ bone marrow-derived cells and comparing the level of vascular endothelial growth factor receptor 1+ bone marrow-derived cells to prior levels.
FILED Monday, November 21, 2005
APPL NO 11/284265
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598048 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Qun-Yong Zhou (Irvine, California);  Clayton M. Bullock (Irvine, California)
ABSTRACT The invention provides a method for screening for a compound for modulating circadian rhythm. The method involves (a) providing a compound that is a Prokineticin 2 (PK2) receptor antagonist or agonist; and (b) determining the ability of the compound to modulate one or more indicia of circadian rhythm function, wherein a compound that modulates one or more indicia of circadian rhythm function is identified as a compound for modulating circadian rhythm. The invention also provides a mouse PK2 receptor nucleic acid, polypeptide and related compositions. Further provided is a method for modulating circadian rhythm of an animal, which involves administering an effective amount of a PK2 receptor antagonist or agonist to an animal. Also provided is an isolated nucleic acid comprising a PK2 gene promoter operatively linked to a heterologous nucleotide sequence.
FILED Tuesday, April 15, 2003
APPL NO 10/417426
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598052 Giordano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Thomas Giordano (Ann Arbor, Michigan);  Ronald Koenig (Ann Arbor, Michigan);  Rork Kuick (Dexter, Michigan);  Samir Hanish (Seattle, Washington);  Yuri Nikiforov (Pittsburgh, Pennsylvania);  Dafydd G. Thomas (Fenton, Michigan)
ABSTRACT The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with thyroid cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of thyroid cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
FILED Tuesday, October 10, 2006
APPL NO 11/545586
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598054 Kovalenko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Immunetics, Inc. (Boston, Massachusetts)
INVENTOR(S) Victor Kovalenko (Saco, Maine);  Andrew E. Levin (Wellesley, Massachusetts);  Lee Anne Beausang (Norfolk, Massachusetts)
ABSTRACT The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-β-D-glucan in a sample.
FILED Friday, April 28, 2006
APPL NO 11/413977
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/25
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598058 Debinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Waldemar Debinski (Winston-Salem, North Carolina);  Jeffrey P. Thompson (Landisville, Pennsylvania)
ABSTRACT This invention provides nucleic acid molecules encoding mutant human interleukin 13 molecules showing varying specificity for the restricted (IL4 independent) IL13 receptor. The mutant hIL13 molecules include those made by substituting the amino acid residues that occur in the alpha-helix regions of native hIL13 with various other amino acid residues. Some of the mutants retain the ability to bind and cause signaling through IL13 receptors, while other mutants do not.
FILED Tuesday, August 24, 2004
APPL NO 10/924558
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.520
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598067 Beavo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Bern (Bern, Switzerland);  University of Washington (Seattle, Washington)
INVENTOR(S) Joseph A. Beavo (Seattle, Washington);  Thomas Seebeck (Ortschwaben, Switzerland);  Scott Haydn Soderling (Beaverton, Oregon);  Ana Rascon (Caracas, Venezuela);  Roya Zoraghi (Nashville, Tennessee);  Stefan Kunz (Bern, Switzerland);  Kewei Gong (Los Angeles, California);  Natalie Glavas (Daly City, California)
ABSTRACT The present invention provides isolated full-length nucleic acid molecules encoding the novel PDE protein of the invention, and methods for uses thereof. The nucleic acid molecules of the invention also include peptide nucleic acids (PNA), and antisense molecules that react with the nucleic acid molecules of the invention. The invention also relates to agonists, antibodies, antagonists or inhibitors of the activity of novel PDE proteins. These compositions are useful for the diagnosis, prevention or treatment of conditions associated with the presence or the deficiency of novel PDE proteins.
FILED Thursday, June 01, 2006
APPL NO 11/421658
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/196
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598071 Brown et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  Institut National de Recherche Scientifique (Quebec, Canada)
INVENTOR(S) Kevin Brown (Kensington, Maryland);  Ning Zhi (Rockville, Maryland);  Peter Tijssen (Pointe-Claire, Canada);  Zoltan Zadori (Montreal, Canada)
ABSTRACT The invention relates to infectious clones of parvovirus B19, methods of cloning infectious B19 clones, and methods of cloning viral genomes that have secondary DNA structures that are unstable in bacterial cells. A B19 infectious clone and methods of producing B19 infectious clones are useful for producing infectious virus. Infectious virus is useful for identifying and developing therapeutically effective compositions for treatment and/or prevention of human parvovirus B19 infections.
FILED Friday, July 09, 2004
APPL NO 10/887770
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/235.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598072 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John A. T. Young (San Diego, California);  Shakti Narayan (Palo Alto, California)
ABSTRACT A cell-free viral uncoating assay is provided.
FILED Wednesday, December 08, 2004
APPL NO 11/007145
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/239
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598077 Horikawa et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Izumi Horikawa (Rockville, Maryland);  J. Carl Barrett (Rockville, Maryland)
ABSTRACT Artificial TERT promoters, which are useful for enhancing the differential expression of operably linked heterologous nucleic acid sequences, such as polypeptide cytotoxins, are disclosed herein. Methods for treating disease cells, such as cancer cells, while minimizing effects on normal, somatic cells by administering therapeutically effective amounts of heterologous nucleic acid sequences operably linked to artificial TERT promoters are provided. Kits containing artificial TERT promoters for enhancing differential expression are also provided.
FILED Thursday, June 05, 2003
APPL NO 10/456830
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598221 Scheinberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) David A. Scheinberg (New York, New York);  Javier Pinilla-Ibarz (New York, New York)
ABSTRACT The present invention is directed to a synthetic peptide comprising a sequence of amino acids containing at least a segment that is an analogue of a native peptide that specifically binds to HLA A0201 or HLA A0301 molecules on a cell characteristic of a pathophysiologic state in a mammal. The synthetic peptide may be derived from native peptides comprising a breakpoint region of the WT1 protein.
FILED Monday, September 12, 2005
APPL NO 11/223139
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598223 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Peter P. Lee (Menlo Park, California);  Tor B. Stuge (Menlo Park, California)
ABSTRACT Methods and compositions for producing target cell reactive lymphocytes, e.g., cytolytic T-lymphocytes, in a subject are provided. In practicing the subject methods, a lymphocyte population is contacted with an effective amount of a target cell peptide mixture of active and inactive peptides to produce lymphocytes reactive, e.g., cytolytic, for the target cell. Also provided are compositions, kits, and systems for practicing the subject methods. The subject invention finds use in a variety of different applications, including therapeutic applications.
FILED Tuesday, July 19, 2005
APPL NO 11/185245
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/15
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598225 Schlom et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Jeffrey Schlom (Potomac, Maryland);  Dennis L. Panicali (Acton, Massachusetts)
ABSTRACT We have discovered that by using a recombinant viral vector, preferably a pox virus vector having at least one insertion site containing a DNA segment encoding prostate-specific antigen (PSA), operably linked to a promoter capable of expression in the host, a specific humoral and cellular immune response to PSA can be generated. The method preferably comprises introducing a sufficient amount of the recombinant pox virus vector into a host to stimulate the immune response, and contacting the host with additional PSA at periodic intervals thereafter. The additional PSA may be added by using a second pox virus vector from a different pox genus. In another embodiment, additional PSA can be added by contacting the host with PSA by a variety of other methods, including in one preferred embodiment adding PSA. The PSA may be formulated with an adjuvant or in a liposomal formulation.
FILED Friday, October 20, 2000
APPL NO 09/693121
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598234 Savage et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Brigham Young University (Provo, Utah)
INVENTOR(S) Paul B. Savage (Springville, Utah);  Chunhong Li (Provo, Utah)
ABSTRACT A series of novel steroid derivatives are described. The steroid derivatives are antibacterial agents. The steroid derivatives also act to sensitize bacteria to other antibiotics including erythromycin and novobiocin.
FILED Friday, July 16, 2004
APPL NO 10/892828
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/182
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598238 Laskin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey);  Rutgers, the State University (New Brunswick, New Jersey);  Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S) Jeffrey D. Laskin (Piscataway, New Jersey);  Ned Heindel (Easton, Pennsylvania);  Diane Heck (Rumson, New Jersey);  Anna Marie Vetrano (North Brunswick, New Jersey);  Christophe Guillon (Bethlehem, Pennsylvania);  Peter DeMatteo (Allentown, Pennsylvania)
ABSTRACT Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.
FILED Friday, July 28, 2006
APPL NO 11/495948
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/222.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598287 Munn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Medical College of Georgia Research Institute, Inc. (Augusta, Georgia)
INVENTOR(S) David Munn (Augusta, Georgia);  Andrew Mellor (Augusta, Georgia)
ABSTRACT The present invention provides improved treatment methods by the administration of both an inhibitor of indoleamine-2,3-dioxygenase in addition to the administration of an additional therapeutic agent.
FILED Tuesday, February 17, 2004
APPL NO 10/780797
ART UNIT 1614 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/419
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598340 Metchetner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Eugene Metchetner (Palo Alto, California);  Igor B. Roninson (Wilmette, Illinois)
ABSTRACT A hybridoma (termed “UIC2 hybridoma”, ATCC Accession No. HB11027) producing monoclonal antibodies (termed “UIC2 mAb”) directed against an extracellular domain of a cell surface P-glycoprotein antigen associated with multidrug resistance in primate cells was produced by fusing a human myeloma cell with a spleen cell derived from a BALB/c mouse immunized with syngeneic 3T3 fibroblasts previously transfected with the isolated human mdr1 cDNA. UIC2 mAb, thus produced, as well as fragments and recombinant derivatives thereof, may be used to detect and isolate multidrug resistant primate cells and human mdr1 gene products, and to reverse multidrug resistance in primate cells, including cells of multidrug resistant human tumors.
FILED Tuesday, November 12, 2002
APPL NO 10/292541
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598341 Hanahan et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Burnham Institue for Medical Research (La Jolla, California);  The Regents of the Universtiy of California (Oakland, California)
INVENTOR(S) Douglas Hanahan (San Francisco, California);  Erkki Ruoslahti (Rancho Santa Fe, California);  Johanna A. Joyce (New York, New York);  Pirjo Laakkonen (Helsinki, Finland)
ABSTRACT The invention provides a conjugate that includes a therapeutic moiety linked to a peptide or peptidomimetic that selectively homes to vasculature of premalignant pancreas. The peptide or peptidomimetic contains at least 5 contiguous amino acids of an amino acid sequence selected from CRSRKG (SEQ ID NO:9) and CEYQLDVE (SEQ ID NO:34), or a conservative variant or peptidomimetic thereof. The invention additionally provides a conjugate containing a therapeutic moiety linked to a peptide or peptidomimetic that selectively homes to pancreatic tumor cells and pancreatic tumor vasculature, the peptide or peptidomimetic comprising at least 5 contiguous amino acids of an amino acid sequence selected from CKAAKNK (SEQ ID NO:15), CKGAKAR (SEQ ID NO:19), and VGVGEWSV (SEQ ID NO:35), or a conservative variant or peptidomimetic thereof.
FILED Friday, October 29, 2004
APPL NO 10/977367
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598342 Andersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Albany Medical College (Albany, New York)
INVENTOR(S) Thomas T. Andersen (Albany, New York);  James A. Bennett (Delmar, New York);  Herbert Jacobson (Albany, New York);  George C. Shields (Clinton, New York);  Karl N. Kirschner (Clinton, New York)
ABSTRACT The invention relates to compounds that include peptide and peptidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
FILED Monday, February 26, 2007
APPL NO 11/678784
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598352 Koide
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Shohei Koide (Rochester, New York)
ABSTRACT A method of identifying a polypeptide monobody having target protein binding activity, said method comprising: providing a host cell comprising (i) a reporter gene under control of a 5′ regulatory region operable in the host cell, (ii) a first chimeric gene which encodes a first fusion polypeptide comprising a target protein, or fragment thereof, fused to a C-terminus of a DNA-binding domain which binds to the 5′ regulatory region of the reporter gene, and (iii) a second chimeric gene which encodes a second fusion polypeptide comprising a polypeptide monobody fused to a transcriptional activation domain; and detecting expression of the reporter gene, which indicates binding of the polypeptide monobody of the second fusion polypeptide to the target protein such that the transcriptional activation domain of the second fusion polypeptide is in sufficient proximity to the DNA-binding domain of the first fusion polypeptide to allow expression of the reporter gene.
FILED Monday, November 19, 2001
APPL NO 10/006760
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598355 Nicchitta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Christopher V. Nicchitta (Durham, North Carolina);  James J. Wassenberg (Durham, North Carolina);  Meredith F. N. Rosser (Durham, North Carolina);  Robyn C. Reed (Durham, North Carolina)
ABSTRACT The present invention discloses characterization of interactions between ligands and Hsp90 proteins, including GRP94, wherein ligand binding to the N-terminal nucleotide binding domain of GRP94 elicits a conformational change that converts the GRP94 from an inactive to an active conformation, and wherein the chaperone and peptide-binding activities of the GRP94 are markedly stimulated. Also disclosed are purification, screening, and therapeutic methods pertaining to the biological activity of GRP94, and in some instances HSP90, based upon the characterization of ligand interactions of Hsp90 peptide-binding proteins, including GRP94.
FILED Thursday, August 01, 2002
APPL NO 10/210333
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/413
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598356 Bedows et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Board of Regents of the University of Nebraska by and on Behalf of the University of Nebraska Medical Center (Omaha, Nebraska)
INVENTOR(S) Elliott Bedows (Bellevue, Nebraska);  Jason A. Wilken (Omaha, Nebraska)
ABSTRACT The present invention relates to a two-step method for isolating proteins from the cystine-knot superfamily based on dye ligand affinity chromatography and reversed-phase chromatography. Advantageously, the method can be performed in a relatively short period of time, involves inexpensive reagents, and requires little sample preparation before and during the purification process. Protein fusions between cystine-knot proteins and proteins of interest are further provided for the isolation of said protein of interest or complexes containing said protein of interest using the two-step method disclosed.
FILED Thursday, July 08, 2004
APPL NO 10/887106
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/413
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598363 Seeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Nadrian C. Seeman (New York, New York);  Baoquan Ding (New York, New York);  Pamela E. Constantinou (New York, New York);  Tong Wang (Brooklyn, New York);  Jens Kopatsch (Brooklyn, New York);  Xiaoping Zhang (Woodside, New York);  Ruojie Sha (Pomona, New York);  Lisa Israel (New York, New York)
ABSTRACT Robust nucleic acid arrays and lattices are assembled based on double crossover cohesion of polygonal units whose edges are composed of nucleic acid multi-crossover domains.
FILED Thursday, June 09, 2005
APPL NO 11/148423
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598739 Vaughan, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) John Thomas Vaughan, Jr. (Stillwater, Minnesota);  Kamil Ugurbil (Minneapolis, Minnesota);  Gregor Adriany (Minneapolis, Minnesota)
ABSTRACT A plurality of linear current elements are configured about a specimen to be imaged. A current in each current element is controlled independent of a current in other current elements to select a gradient and to provide radio frequency shimming. Each current element is driven by a separate channel of a transmitter and connected to a separate channel of a multi-channel receiver. The impedance, and therefore, the current, in each current element is controlled mechanically or electrically.
FILED Monday, April 21, 2003
APPL NO 10/420541
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/318
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599732 Sevick-Muraca et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Eva M. Sevick-Muraca (Edinburg, Texas);  Alan B. Thompson (Hillsboro, Oregon);  Roy Ranadhir (Edinburg, Texas)
ABSTRACT According to one embodiment of the invention, a method for biomedical imaging includes directing time-varying excitation light at a surface area of a light scattering material, the material comprising a fluorescent target. Time-varying emission light from the fluorescent target is detected, substantially at a two-dimensional sensor surface, in response to the time-varying excitation light stimulating the fluorescent target. The time-varying emission light is filtered to reject excitation light re-emitted from the material. A three-dimensional image of the fluorescent target is generated based on the detection substantially at the sensor surface.
FILED Friday, June 18, 2004
APPL NO 10/872333
ART UNIT 3737 — Optics
CURRENT CPC
Surgery
6/476
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07596915 Lee et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Davis Energy Group, Inc. (Davis, California)
INVENTOR(S) Brain E. Lee (Corral de Tierra, California);  Stephan K. Barsun (Davis, California);  Richard C. Bourne (Davis, California);  Marc A. Hoeschele (Davis, California);  David A. Springer (Winters, California)
ABSTRACT A method of forming an insulated concrete foundation is provided comprising constructing a foundation frame, the frame comprising an insulating form having an opening, inserting a pocket former into the opening; placing concrete inside the foundation frame; and removing the pocket former after the placed concrete has set, wherein the concrete forms a pocket in the placed concrete that is accessible through the opening. The method may further comprise sealing the opening by placing a sealing plug or sealing material in the opening. A system for forming an insulated concrete foundation is provided comprising a plurality of interconnected insulating forms, the insulating forms having a rigid outer member protecting and encasing an insulating material, and at least one gripping lip extending outwardly from the outer member to provide a pest barrier. At least one insulating form has an opening into which a removable pocket former is inserted. The system may also provide a tension anchor positioned in the pocket former and a tendon connected to the tension anchor.
FILED Tuesday, May 29, 2007
APPL NO 11/806060
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/223.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597147 Vitek et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Shell Oil Company (Houston, Texas)
INVENTOR(S) John Michael Vitek (Oak Ridge, Tennessee);  Michael Patrick Brady (Oak Ridge, Tennessee);  Joseph Arno Horton, Jr. (Oak Ridge, Tennessee)
ABSTRACT Systems, methods, and heaters for treating a subsurface formation are described herein. Systems and methods for making heaters are described herein. At least one heater includes a ferromagnetic conductor and an electrical conductor. The electrical conductor is electrically coupled to the ferromagnetic conductor. The heater provides a first amount of heat at a lower temperature. The heater may provide a second reduced amount of heat when the heater reaches a selected temperature, or enters a selected temperature range, at which the ferromagnetic conductor undergoes a phase transformation.
FILED Friday, April 20, 2007
APPL NO 11/788863
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Wells
166/302
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597236 Tolle et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Charles R. Tolle (Idaho Falls, Idaho);  Denis E. Clark (Idaho Falls, Idaho);  Herschel B. Smartt (Idaho Falls, Idaho);  Karen S. Miller (Idaho Falls, Idaho)
ABSTRACT A material-forming tool and a method for forming a material are described including a shank portion; a shoulder portion that releasably engages the shank portion; a pin that releasably engages the shoulder portion, wherein the pin defines a passageway; and a source of a material coupled in material flowing relation relative to the pin and wherein the material-forming tool is utilized in methodology that includes providing a first material; providing a second material, and placing the second material into contact with the first material; and locally plastically deforming the first material with the material-forming tool so as mix the first material and second material together to form a resulting material having characteristics different from the respective first and second materials.
FILED Tuesday, August 16, 2005
APPL NO 11/205616
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal fusion bonding
228/112.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597475 Shu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Deming Shu (Darien, Illinois);  Hanfei Yan (Moriches, New York);  Jorg M. Maser (Oak Park, Illinois)
ABSTRACT A multidimensional alignment apparatus is provided for multidimensional aligning of two linear multilayer Laue lenses (MLLs) for two-dimensional hard X-ray focusing. The multidimensional alignment apparatus precisely aligns and ensures stability of two linear MLLs performing hard x-ray focusing. The multidimensional alignment apparatus includes a base, a lower stages group controlling a first upstream MLL, an upper stages group positioned over the lower stages group controlling a second downstream MLL and an upper stage support attached to the base. The lower stages group provides five degrees of freedom precision positioning adjustment for the first upstream MLL. The second downstream MLL is mounted on the upper stages group with three degrees of freedom adjustment capability.
FILED Thursday, September 18, 2008
APPL NO 12/233137
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/205
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597819 Hankins
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Matthew G. Hankins (Albuquerque, New Mexico)
ABSTRACT Etchant solutions comprising a redox buffer can be used during the release etch step to reduce damage to the structural layers of a MEMS device that has noble material films. A preferred redox buffer comprises a soluble thiophosphoric acid, ester, or salt that maintains the electrochemical potential of the etchant solution at a level that prevents oxidation of the structural material. Therefore, the redox buffer preferentially oxidizes in place of the structural material. The sacrificial redox buffer thereby protects the exposed structural layers while permitting the dissolution of sacrificial oxide layers during the release etch.
FILED Monday, December 20, 2004
APPL NO 11/017108
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/79.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597860 Rabinovich et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Alexander Rabinovich (Swampscott, Massachusetts);  Nikolai Alexeev (Moscow, Russian Federation);  Leslie Bromberg (Sharon, Massachusetts);  Daniel R. Cohn (Chestnut Hill, Massachusetts);  Andrei Samokhin (Moscow, Russian Federation)
ABSTRACT A novel apparatus and method is disclosed for a plasmatron fuel converter (“plasmatron”) that efficiently uses electrical energy to produce hydrogen rich gas. The volume and shape of the plasma discharge is controlled by a fluid flow established in a plasma discharge volume. A plasmatron according to this invention produces a substantially large effective plasma discharge volume allowing for substantially greater volumetric efficiency in the initiation of chemical reactions within a volume of bulk fluid reactant flowing through the plasmatron.
FILED Friday, April 08, 2005
APPL NO 11/101926
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/186.40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07597862 Meikrantz et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David H. Meikrantz (Idaho Falls, Idaho);  Terry A. Todd (Aberdeen, Idaho);  Troy J. Tranter (Idaho Falls, Idaho);  E. Philip Horwitz (Naperville, Illinois)
ABSTRACT A method of recovering daughter isotopes from a radioisotope mixture. The method comprises providing a radioisotope mixture solution comprising at least one parent isotope. The at least one parent isotope is extracted into an organic phase, which comprises an extractant and a solvent. The organic phase is substantially continuously contacted with an aqueous phase to extract at least one daughter isotope into the aqueous phase. The aqueous phase is separated from the organic phase, such as by using an annular centrifugal contactor. The at least one daughter isotope is purified from the aqueous phase, such as by ion exchange chromatography or extraction chromatography. The at least one daughter isotope may include actinium-225, radium-225, bismuth-213, or mixtures thereof. A liquid-liquid extraction system for recovering at least one daughter isotope from a source material is also disclosed.
FILED Wednesday, September 20, 2006
APPL NO 11/533592
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598034 Miller et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Benjamin L. Miller (Penfield, New York);  Christopher M. Strohsahl (Saugerties, New York)
ABSTRACT Method of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.
FILED Monday, January 03, 2005
APPL NO 10/584875
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598037 Perov et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) U Chicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Alexander N. Perov (Woodridge, Illinois);  Darrell P. Chandler (Yorkville, Illinois)
ABSTRACT A method and apparatus are provided for implementing non-destructive quality control of substrates and printed biological microarrays. A method and apparatus are provided for implementing quality control of gel-based microarrays prepared by dispensing a gel-forming composition on a solid substrate. The method utilizes the difference between the wettability properties of a supporting substrate and a gel, where the gel is hydrophilic. Condensation of vapor of a chemically inert water-soluble liquid, such as water or glycerol, on the surface of a substrate under inspection creates a layer of tiny droplets that affect both transmission and scattering of light on the surface. A pattern of condensation, characterized by spatial distribution, average size of the droplets and spacing between the droplets, reflects variation in wetting properties of the substrate. The pattern of condensation circumscribes printed microarray features to be non-destructively imaged and analyzed.
FILED Wednesday, July 12, 2006
APPL NO 11/485203
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598224 Zamora et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)
ASSIGNEE(S) BioSurface Engineering Technologies, Inc. (Rockville, Maryland)
INVENTOR(S) Paul O. Zamora (Gaithersburg, Maryland);  Louis A. Pena (Poquott, New York);  Xinhua Lin (Plainview, New York)
ABSTRACT The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.
FILED Thursday, February 24, 2005
APPL NO 11/065970
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/18
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598346 Altier et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) Pioneer Hi-Bred International, Inc. (Johnston, Iowa);  E. I. du Pont de Nemours and Company (Wilmington, Delaware);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Daniel J. Altier (Granger, Iowa);  Virginia C. Crane (Des Moines, Iowa);  Irina Ellanskaya (Kyiv, Ukraine);  Natalia Ellanskaya, legal representative (Kyiv, Ukraine);  Jacob T. Gilliam (Norwalk, Iowa);  Jennie Hunter-Cevera (Elliott City, Maryland);  James K. Presnail (Avondale, Pennsylvania);  Eric J. Schepers (Port Deposit, Maryland);  Carl R. Simmons (Des Moines, Iowa);  Tamas Torok (Richmond, California);  Nasser Yalpani (Johnston, Iowa)
ABSTRACT The invention relates to compositions including amino acid sequences isolated from fungal fermentation broths and methods for protecting a plant from a pathogen, particularly a fungal pathogen.
FILED Tuesday, May 15, 2007
APPL NO 11/748994
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599059 Laurence et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ted A. Laurence (Livermore, California);  Shimon Weiss (Los Angels, California)
ABSTRACT A method for analyzing/monitoring the properties of species that are labeled with fluorophores. A detector is used to detect photons emitted from species that are labeled with one or more fluorophores and located in a confocal detection volume. The arrival time of each of the photons is determined. The interval of time between various photon pairs is then determined to provide photon pair intervals. The number of photons that have arrival times within the photon pair intervals is also determined. The photon pair intervals are then used in combination with the corresponding counts of intervening photons to analyze properties and interactions of the molecules including brightness, concentration, coincidence and transit time. The method can be used for analyzing single photon streams and multiple photon streams.
FILED Friday, July 25, 2003
APPL NO 10/521632
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/317
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599876 Lo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Aeronautical Systems Center (ASC)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Advanced Simulation and Computing Program (ASC)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Andrew Lo (Lexington, Massachusetts);  Tung Chan (Cambridge, Massachusetts);  Tomaso Poggio (Wellesley, Massachusetts)
ABSTRACT Disclosed herein is an automated Electronic Market-Maker, comprising a Market Quality Control Module for generating trading recommendations to maintain market quality; an Inventory Control Module for generating trading recommendations to maintain inventory; a Speculation Module for generating trading recommendations to generate profits; and an Arbitration Module to receive trading recommendations from said Market Quality Control Module, Inventory Control Module, and Speculation Control Module and resolve any conflicts between the received recommendations.
FILED Wednesday, March 15, 2000
APPL NO 09/526633
ART UNIT 3692 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07600095 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota)
ABSTRACT Executing a scatter operation on a parallel computer includes: configuring a send buffer on a logical root, the send buffer having positions, each position corresponding to a ranked node in an operational group of compute nodes and for storing contents scattered to that ranked node; and repeatedly for each position in the send buffer: broadcasting, by the logical root to each of the other compute nodes on a global combining network, the contents of the current position of the send buffer using a bitwise OR operation, determining, by each compute node, whether the current position in the send buffer corresponds with the rank of that compute node, if the current position corresponds with the rank, receiving the contents and storing the contents in a reception buffer of that compute node, and if the current position does not correspond with the rank, discarding the contents.
FILED Thursday, April 19, 2007
APPL NO 11/737286
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/28
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE40929 Gray et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Joe W. Gray (San Francisco, California);  Daniel Pinkel (Lafayette, California);  Olli-Pekka Kallioniemi (Turku, Finland);  Anne Kallioniemi (Tampere, Finland);  Masaru Sakamoto (Tokyo, Japan)
ABSTRACT Methods and compositions for staining based upon nucleic acid sequence that employ nudeic nucleic acid probes are provided. Said methods produce staining patterns that can be tailored for specific cytogenetic analyses. Said probes are appropriate for in situ hybridization and stain both interphase and metaphase chromosomal material with reliable signals. The nucleic acid probes are typically of a complexity greater than 50 kb, the complexity depending upon the cytogenetic application. Methods and reagents are provided for the detection of genetic rearrangements. Probes and test kits are provided for use in detecting genetic rearrangements, particularly for use in tumor cytogenetics, in the detection of disease related loci, specifically cancer, such as chronic myelogenous leukemia (CML), retinoblastoma, ovarian and uterine cancers, and for biological dosimetry. Methods and reagents are described for cytogenetic research, for the differentiation of cytogenetically similar but genetically different diseases, and for many prognostic and diagnostic applications.
FILED Friday, March 31, 2006
APPL NO 11/396221
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07597941 Sunkara et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Mahendra Kumar Sunkara (Louisville, Kentucky);  Gopinath Bhimarasetti (Hillsboro, Oregon)
ABSTRACT A method of synthesizing and controlling the internal diameters, conical angles, and morphology of tubular carbon nano/micro structures. Different morphologies can be synthesized included but not limited to cones, straight tubes, nozzles, cone-on-tube (funnels), tube-on-cone, cone-tube-cone, n-staged structures, multijunctioned tubes, Y-junctions, dumbbell (pinched morphology) and capsules. The process is based on changing the wetting behavior of a low melting metals such as gallium, indium, and aluminum with carbon using a growth environment of different gas phase chemistries. The described carbon tubular morphologies can be synthesized using any kind of gas phase excitation such as, but not limited to, microwave excitation, hot filament excitation, thermal excitation and Radio Frequency (RF) excitations. The depositions area is only limited by the substrate area in the equipment used and not limited by the process. The internal diameters of the carbon tubular structures can be varied from a few nm to as high as about 20 microns. The wall thickness is about 10-20 nm. The carbon tubular structures can be formed open on both ends are directly applicable to micro-fluidics. Gallium required for the growth of the carbon tubes can be supplied either as a thin film on the substrate or could be supplied through the gas phase with different precursors such as Tri-methyl gallium. Seamless Y-junctions with no internal obstructions can be synthesized without the need of templates. Multi-channeled junctions can also be synthesized without any internal obstructions. Gallium that partially fills the carbon structures can be removed from the tubes by simple heating in vacuum at temperature above 600°.
FILED Thursday, September 09, 2004
APPL NO 10/937738
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/576
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598087 Bright
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Frank V. Bright (Williamsville, New York)
ABSTRACT This invention provides protein or polypeptide imprinted polymers with integrated emission sites (PIPIES) for detecting the presence of a protein or polypeptide analyte comprising templated sites which are specific for the analyte. At or near the templated sites are selectively placed reporter molecules. A method is also disclosed for the preparation of the PIPIES and the use of these for the detection of analytes.
FILED Friday, January 07, 2005
APPL NO 11/031318
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/164
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598313 Emrick et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Todd S. Emrick (South Deerfield, Massachusetts);  Kurt Breitenkamp (Northampton, Massachusetts)
ABSTRACT Polymer capsules from amphiphilic graft copolymers comprising reactive, hydrophobic polyolefin backbones, and hydrophilic poly(ethylene glycol) (PEG) grafts are produced by self-assembly of the polymers at the oil-water interface, and crosslinking the assembly with bis-cyclooctene PEG derivatives in conjunction with ring-open metathesis polymerization catalysts. The use of the graft copolymer architecture in capsule synthesis provides significant opportunities to tune both the surface properties, in terms of recognition, and the membrane properties, in terms of mechanical strength, encapsulation, and release.
FILED Friday, September 03, 2004
APPL NO 10/934084
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
524/553
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598344 Belcher et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Angela M. Belcher (Lexington, Massachusetts);  Christine J. Schmidt (Austin, Texas);  Kiley P. H. Miller (Somerville, Massachusetts);  Archit Sanghvi (Austin, Texas)
ABSTRACT The present invention includes a bifunctional specificity structure that includes a peptide linker having a first and a second binding domain, wherein the first binding domain is selective for a first biomaterial and the second binding domain is selective for a second biomaterial. The present invention also includes a method of making and identifying the bifunctional structure of the present invention and methods of using the same.
FILED Thursday, September 04, 2003
APPL NO 10/654623
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/327
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598363 Seeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Nadrian C. Seeman (New York, New York);  Baoquan Ding (New York, New York);  Pamela E. Constantinou (New York, New York);  Tong Wang (Brooklyn, New York);  Jens Kopatsch (Brooklyn, New York);  Xiaoping Zhang (Woodside, New York);  Ruojie Sha (Pomona, New York);  Lisa Israel (New York, New York)
ABSTRACT Robust nucleic acid arrays and lattices are assembled based on double crossover cohesion of polygonal units whose edges are composed of nucleic acid multi-crossover domains.
FILED Thursday, June 09, 2005
APPL NO 11/148423
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598513 Kouvetakis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents, Acting for and on behalf of Arizona State University, A Corporate Body Organized under Arizona Law (, None)
INVENTOR(S) John Kouvetakis (Mesa, Arizona);  Matthew Bauer (Hillsboro, Oregon);  John Tolle (Gilbert, Arizona)
ABSTRACT A novel method for synthesizing device-quality alloys and ordered phases in a Si—Ge—Sn system uses a UHV-CVD process and reactions of SnD4 with SiH3GeH3. Using the method, single-phase SixSnyGe1-x-y semiconductors (x≦0.25, y≦0.11) are grown on Si via Ge1-xSnx buffer layers The Ge1-xSnx buffer layers facilitate heteroepitaxial growth of the SixSnyGe1-x-y films and act as compliant templates that can conform structurally and absorb the differential strain imposed by the more rigid Si and Si—Ge—Sn materials. The SiH3GeH3 species was prepared using a new and high yield method that provided high purity semiconductor grade material.
FILED Monday, June 14, 2004
APPL NO 10/559979
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598514 Freedman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Microsoft Corporation (Redmond, Washington)
INVENTOR(S) Michael H. Freedman (Redmond, Washington);  Chetan V. Nayak (Santa Monica, California);  Sankar Das Sarma (Potomac, Maryland)
ABSTRACT A quantum computer can only function stably if it can execute gates with extreme accuracy. “Topological protection” is a road to such accuracies. Quasi-particle interferometry is a tool for constructing topologically protected gates. Assuming the corrections of the Moore-Read Model for ν=5/2's FQHE (Nucl. Phys. B 360, 362 (1991)) we show how to manipulate the collective state of two e/4-charge anti-dots in order to switch said collective state from one carrying trivial SU(2) charge, |1>, to one carrying a fermionic SU(2) charge |ε>. This is a NOT gate on the {|1>, |ε>} qubit and is effected by braiding of an electrically charged quasi particle σ which carries an additional SU(2)-charge. Read-out is accomplished by σ-particle interferometry.
FILED Wednesday, May 28, 2008
APPL NO 12/128417
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598723 Gaillard et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Clemson University (, None)
INVENTOR(S) Jay Gaillard (Clemson, South Carolina);  Razvan Marian Ciocan (Central, South Carolina);  Malcolm Skove (Central, South Carolina);  Apparao M. Rao (Anderson, South Carolina)
ABSTRACT A method and system is disclosed that can be used to directly detect and analyze an electric signal electrostatically induced a semi-conductive or conductive element at resonance. Through detection of the changes in the characteristics of the signal from the element, the disclosed devices can detect, for instance, presence of chemical/biological species in a sample or measure physical parameters of a sample such as pressure/acceleration, magnetic force, temperature, and/or extremely small masses. The disclosed systems include one or more micro- or nano-sized elements. Through modulation of an electric charge on a counter-electrode that is located at a pre-determined distance from the element, a modulating charge can be induced upon the element. Resonance can be directly detected via electronic monitoring of the induced signal for the higher harmonics of the natural resonant frequency.
FILED Tuesday, February 14, 2006
APPL NO 11/354268
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/76.420
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599069 Toussaint, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
Materials Research Science and Engineering Centers (MRSECs)
APPLICANT(S)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Kimani C. Toussaint, Jr. (Chicago, Illinois);  Norbert F. Scherer (Winnetka, Illinois);  Justin E. Jureller (Chicago, Illinois);  Sungnam Park (Chicago, Illinois)
ABSTRACT Provided are techniques for generating optical vector beams (e.g., radially and azimuthally polarized light) using passive or active phase stable optical interferometry. Techniques may split an input optical beam into at least two output beams, and then couple those beams simultaneously into a passively phase stable optical interferometer. Beam splitting may be achieved by a diffractive optical element and coupling may be achieved by a single refractive optical device (lenses) or by a single mirror device (e.g., parabolic and spherical). The interferometer may provide the ability to manipulate (or transform) the polarization of part of the wavefront of each beam, as well as the ability to manipulate (or transform) the phase of part of the wavefront of each beam, such that the beams when combined have a vector beam polarization state.
FILED Friday, May 05, 2006
APPL NO 11/418694
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/491
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599876 Lo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Aeronautical Systems Center (ASC)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Advanced Simulation and Computing Program (ASC)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Andrew Lo (Lexington, Massachusetts);  Tung Chan (Cambridge, Massachusetts);  Tomaso Poggio (Wellesley, Massachusetts)
ABSTRACT Disclosed herein is an automated Electronic Market-Maker, comprising a Market Quality Control Module for generating trading recommendations to maintain market quality; an Inventory Control Module for generating trading recommendations to maintain inventory; a Speculation Module for generating trading recommendations to generate profits; and an Arbitration Module to receive trading recommendations from said Market Quality Control Module, Inventory Control Module, and Speculation Control Module and resolve any conflicts between the received recommendations.
FILED Wednesday, March 15, 2000
APPL NO 09/526633
ART UNIT 3692 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/37
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07598371 Willson et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Aeronautics and Space Administration (NASA)
National Space Biomedical Research Institute (NSBRI)
APPLICANT(S)
ASSIGNEE(S) University of Houston (Houston, Texas)
INVENTOR(S) Richard C. Willson (Houston, Texas);  Jason C. Murphy (North Wales, Pennsylvania)
ABSTRACT An immobilized metal affinity chromatography (IMAC) method for separating and/or purifying compounds containing a non-shielded purine or pyrimidine moiety or group such as nucleic acid, presumably through interaction with the abundant aromatic nitrogen atoms in the purine or pyrimidine moiety. The method can also be used to purify compounds containing purine or pyrimidine moieties where the purine and pyrimidine moieties are shielded from interaction with the column matrix from compounds containing a non-shielded purine or pyrimidine moiety or group. Thus, double-stranded plasmid and genomic DNA, which has no low binding affinity can be easily separated from RNA and/or oligonucleotides which bind strongly to metal-charged chelating matrices. IMAC columns clarify plasmid DNA from bacterial alkaline lysates, purify a ribozyme, and remove primers and other contaminants from PCR reactions. The metal ion affinity of yeast RNA decreases in the order: copper (II), nickel (II), zinc (II), and cobalt (II).
FILED Tuesday, November 06, 2001
APPL NO 09/994701
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/25.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599061 Ting et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) David Z. Ting (Arcadia, California);  Cory J. Hill (Pasadena, California);  Sumith V. Bandara (Stevenson Ranch, California);  Sarath D. Gunapala (Stevenson Ranch, California)
ABSTRACT The present invention is directed to methods of photonic crystal formation, and to methods and apparatus for using such photonic crystals, particularly in conjunction with detector arrays. Photonic crystal parameters and detector array parameters are compared to optimize the selection and orientation of a photonic crystal shape. A photonic crystal is operatively positioned relative to a plurality of light sensors. The light sensors can be separated by a pitch distance and positioned within one half of the pitch distance of an exit surface of the photonic crystals.
FILED Thursday, July 21, 2005
APPL NO 11/188226
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599074 Sun et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Ke-Xun Sun (Stanford, California);  Robert L. Byer (Stanford, California)
ABSTRACT An angular magnification effect of diffraction is exploited to provide improved sensing and scanning. This effect is most pronounced for a normal or near-normal incidence angle in combination with a grazing diffraction angle, so such configurations are preferred. Angular sensitivity can be further enhanced because the width of the diffracted beam can be substantially less than the width of the incident beam. Normal incidence configurations with two symmetric diffracted beams are preferred, since rotation and vertical displacement can be readily distinguished. Increased sensitivity to vertical displacement can be provided by incorporating an interferometer into the measurement system. Quad cell detectors can be employed to provide sensitivity to rotation about the grating surface normal. A 2-D grating can be employed to provide sensitivity to angular displacements in two different planes (e.g., pitch and yaw). Combined systems can provide sensitivity to vertical displacement and to all three angular degrees of freedom.
FILED Tuesday, June 19, 2007
APPL NO 11/820720
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/614
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599896 Peters, II
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Richard Alan Peters, II (Nashville, Tennessee)
ABSTRACT An architecture for robot intelligence enables a robot to learn new behaviors and create new behavior sequences autonomously and interact with a dynamically changing environment. Sensory information is mapped onto a Sensory Ego-Sphere (SES) that rapidly identifies important changes in the environment and functions much like short term memory. Behaviors are stored in a DBAM that creates an active map from the robot's current state to a goal state and functions much like long term memory. A dream state converts recent activities stored in the SES and creates or modifies behaviors in the DBAM.
FILED Monday, February 04, 2008
APPL NO 12/025540
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/14
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 07597692 Weaver et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) James C. Weaver (Sudbury, Massachusetts);  R. Rox Anderson (Lexington, Massachusetts);  Terry O. Herndon (Carlisle, Massachusetts)
ABSTRACT The present invention relates to microscission methods and devices used for the manipulation or modification of the body tissue by the formation of microconduits in a tissue. The term “microconduit” refers to a small opening, channel, or hole into, or through, a tissue, that allows transfer of materials by liquid flow, and by electrophoresis, the microconduit being formed upon impact of a plurality of accelerated microparticles with the surface of the tissue. This process of “microscission” comprises forming at least one microconduit in tissue including the steps of: accelerating a plurality of microparticles to a velocity that causes the microparticles to penetrate a region of tissue surface upon impingement of the microparticles on the tissue surface; and directing the microparticle towards the region of tissue surface, thereby causing the microparticles to penetrate the tissue and form a microconduit in the tissue.
FILED Monday, March 15, 2004
APPL NO 10/800587
ART UNIT 3767 — Optics
CURRENT CPC
Surgery
64/500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07598513 Kouvetakis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents, Acting for and on behalf of Arizona State University, A Corporate Body Organized under Arizona Law (, None)
INVENTOR(S) John Kouvetakis (Mesa, Arizona);  Matthew Bauer (Hillsboro, Oregon);  John Tolle (Gilbert, Arizona)
ABSTRACT A novel method for synthesizing device-quality alloys and ordered phases in a Si—Ge—Sn system uses a UHV-CVD process and reactions of SnD4 with SiH3GeH3. Using the method, single-phase SixSnyGe1-x-y semiconductors (x≦0.25, y≦0.11) are grown on Si via Ge1-xSnx buffer layers The Ge1-xSnx buffer layers facilitate heteroepitaxial growth of the SixSnyGe1-x-y films and act as compliant templates that can conform structurally and absorb the differential strain imposed by the more rigid Si and Si—Ge—Sn materials. The SiH3GeH3 species was prepared using a new and high yield method that provided high purity semiconductor grade material.
FILED Monday, June 14, 2004
APPL NO 10/559979
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/14
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07598774 Belluomini et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Wendy Ann Belluomini (Austin, Texas);  Aniket Mukul Saha (Austin, Texas)
ABSTRACT An limited-switch dynamic logic (LSDL) circuit provides reduced power consumption by reducing clock power dissipation. By clocking LSDL gates with a clock signal having a reduced voltage swing in the evaluation phase, the LSDL gates are permitted to operate, while reducing the clock power consumption dramatically. Since clock power consumption dominates in LSDL circuits, the reduction in clock power dissipation results in a significant reduction in overall circuit power consumption. The reduced swing clock is produced at a plurality of local clock buffers by supplying the local clock buffers with an extra power supply rail that is switched onto the clock distribution lines by the local clock buffers in response to the full-swing evaluate phase clock received from the global clock distribution network by the local clock buffers.
FILED Wednesday, June 25, 2008
APPL NO 12/145715
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Electronic digital logic circuitry
326/121
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07599594 Fitz et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S) John L. Fitz (Baltimore, Maryland);  Daniel S. Hinkel (Sykesville, Maryland);  Scott C. Horst (Sykesville, Maryland)
ABSTRACT The present invention is a method of fabricating a waveguide using a sacrificial spacer layer. The first step in this process is to fabricate the underlying optical semiconductor structure. A trench is then etched in this structure and a sacrificial spacer layer is deposited in the trench. The waveguide is then created in the trench on the sacrificial spacer layer. User-defined portions of the sacrificial spacer layer are subsequently removed to create air gaps between the waveguide and the sidewalls of the trench in the optical semiconductor.
FILED Wednesday, June 07, 2006
APPL NO 11/452568
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/129
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07597014 Tans
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Commerce (Washington, District of Columbia)
INVENTOR(S) Pieter P. Tans (Boulder, Colorado)
ABSTRACT A system and method for using an air collection device to collect a continuous air sample as the device descends through the atmosphere are provided. The air collection device may be one or more coils of thin-walled elongated hollow tubing having a small interior diameter. The thin-walled elongated hollow tubing may be of a substantially nonreactive and nonabsorptive material such as stainless steel. A valve or the like controls the flow of air into and out of the tubing with one of the ends of the tubing closed and the other of the ends open at the beginning or end of the ascent and closed substantially at the end of the descent to seal the continuous air sample in the air collection device. The air collection device may be insulated and have cushioning. Once the continuous air sample is collected in the air collection device, it is analyzed to determine the presence and mole fraction of trace gases at different altitudes in the atmosphere. A high resolution continuous vertical profile of the trace gas may be created. The air collection device may also be used to store a sample gas using a compressor which draws or pushes the gas into the air collection device over a selected period of time. The stored gas may be analyzed in the same manner as the atmospheric air to obtain a time history of the gas sample.
FILED Tuesday, August 15, 2006
APPL NO 11/464607
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/864.510
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 07598049 Ray et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S) Satoris, Inc. (San Jose, California);  The Borad of Trustees of the Leland Stanford Junior University (Palo Alto, California);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Sandip Ray (San Francisco, California);  Anton Wyss-Coray (Belmont, California)
ABSTRACT The inventors have discovered a collection of proteinaceous biomarkers (“AD biomarkers) which can be measured in peripheral biological fluid samples to aid in the diagnosis of neurodegenerative disorders, particularly Alzheimer's disease and mild cognitive impairment (MCI). The invention further provides methods of identifying candidate agents for the treatment of Alzheimer's disease by testing prospective agents for activity in modulating AD biomarker levels.
FILED Friday, November 19, 2004
APPL NO 10/993813
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07598371 Willson et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Aeronautics and Space Administration (NASA)
National Space Biomedical Research Institute (NSBRI)
APPLICANT(S)
ASSIGNEE(S) University of Houston (Houston, Texas)
INVENTOR(S) Richard C. Willson (Houston, Texas);  Jason C. Murphy (North Wales, Pennsylvania)
ABSTRACT An immobilized metal affinity chromatography (IMAC) method for separating and/or purifying compounds containing a non-shielded purine or pyrimidine moiety or group such as nucleic acid, presumably through interaction with the abundant aromatic nitrogen atoms in the purine or pyrimidine moiety. The method can also be used to purify compounds containing purine or pyrimidine moieties where the purine and pyrimidine moieties are shielded from interaction with the column matrix from compounds containing a non-shielded purine or pyrimidine moiety or group. Thus, double-stranded plasmid and genomic DNA, which has no low binding affinity can be easily separated from RNA and/or oligonucleotides which bind strongly to metal-charged chelating matrices. IMAC columns clarify plasmid DNA from bacterial alkaline lysates, purify a ribozyme, and remove primers and other contaminants from PCR reactions. The metal ion affinity of yeast RNA decreases in the order: copper (II), nickel (II), zinc (II), and cobalt (II).
FILED Tuesday, November 06, 2001
APPL NO 09/994701
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/25.400
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07598897 Kirichenko
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Communications-Electronics Research, Development and Engineering Center (CERDEC)
Department of the Navy (DON)
Office of Naval Research (ONR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) HYPRES, Inc. (Elmsford, New York)
INVENTOR(S) Dmitri Kirichenko (Pleasantville, New York)
ABSTRACT A superconducting Analog-to-Digital Converter (ADC) employing rapid-single-flux-quantum (RSFQ) logic is disclosed. The ADC has only superconductor active components, and is characterized as being an Nth-order bandpass sigma-delta ADC, with the order “N” being at least 2. The ADC includes a sequence of stages, which stages include feedback loops and resonators. The ADC further includes active superconducting components which directionally couple resonator pairs of adjacent stages. The active superconducting components electrically shield the higher order resonator from the lower order resonator. These active superconductor components include a superconducting quantum interference device (SQUID) amplifier, which is inductively coupled to the higher order resonator, and may include a Josephson transmission line (JTL), which is configured to electrically connect the SQUID amplifier to the lower order resonator. The first stage of ADC may employ an implicit feedback loop.
FILED Thursday, December 13, 2007
APPL NO 11/955666
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/172
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 07598061 Forsberg et al.
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) The State of Oregon, Acting By and Through the State Board of Higher Education; Oregon State Univ (Corvallis, Oregon)
INVENTOR(S) Neil E. Forsberg (Corvallis, Oregon);  Steven B. Puntenney (Independence, Oregon)
ABSTRACT Methods are disclosed for detecting, quantifying and/or identifying a fungal species in a sample or for diagnosing jejunal hemorrhage syndrome in a subject. The methods generally include amplifying a fungal nucleic acid sequence present in the sample using a primer selected from the group consisting of: SEQ. ID NO 5, SEQ. ID NO 6, SEQ. ID NO 7, SEQ. ID NO 8, SEQ. ID NO 9, SEQ. ID NO 10, SEQ. ID NO 11, SEQ. ID NO 12, SEQ. ID NO 13, SEQ. ID NO 14 or SEQ. ID NO 16; and observing or measuring the amplified nucleic acid sequence. The fungal species can thereby be detected, quantified, and/or identified. Fungal contamination also can be detected or measured in a biological or feed or food sample.
FILED Wednesday, March 14, 2007
APPL NO 11/724596
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07598403 Salvatore et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The University of South Carolina Research Foundation (Columbia, South Carolina)
INVENTOR(S) Brian A. Salvatore (Shreveport, Louisiana);  Ferdinand C. Solis (Lexington, South Carolina)
ABSTRACT Processes for the preparation of biologically active chromanones are disclosed, including processes for the preparation of intermediates useful in the preparation of the biologically active chromanones. The chromanones and the intermediates disclosed herein may be useful for a variety of therapies, including the treatment of various cancers and the treatment of inflammation and inflammation related disorders.
FILED Monday, May 17, 2004
APPL NO 10/557065
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/401
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 06, 2009.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2009/fedinvent-patents-20091006.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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