FedInvent™ Patents

Patent Details for Tuesday, November 03, 2009 

This page was updated on Monday, March 27, 2023 at 01:28 AM GMT

Department of Defense (DOD) 

US 07610946 Morris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Mark C. Morris (Phoenix, Arizona);  Steve H. Halfmann (Chandler, Arizona);  Jason C. Smoke (Phoenix, Arizona)
ABSTRACT A core assembly including two cores is used to manufacture a blade. The first core has an outer surface shaped to complement the tip wall bottom surface. The second core has a tip surface, a side surface, and a protrusion or a depression. The tip surface is shaped to complement at least a portion of the tip wall top surface and is configured to be disposed proximate the first core. The side surface is shaped to complement at least a portion of the side wall, and the protrusion extends from the second core side surface to contact at least a portion of the ceramic mold inner surface. In embodiments employing a depression, the depression is formed in the side surface.
FILED Friday, January 05, 2007
APPL NO 11/650265
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal founding
164/516
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611324 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ching-Pang Lee (Cincinnati, Ohio);  Eric Alan Estill (Morrow, Ohio);  James Harvey Laflen (Loveland, Ohio);  Paul Hadley Vitt (Hamilton, Ohio);  Michael Elliot Wymore (Madison, Alabama)
ABSTRACT A method of assembling a gas turbine engine is provided. The method includes coupling at least one turbine nozzle segment within the gas turbine engine. The at least one turbine nozzle segment includes at least one airfoil vane extending between an inner band and an outer band that includes an aft flange and a radial inner surface. The method also includes coupling at least one turbine shroud segment downstream from the at least one turbine nozzle segment, wherein the at least one turbine shroud segment includes a leading edge and a radial inner surface, coupling a cooling fluid source in flow communication with the at least one turbine nozzle segment such that cooling fluid channeled to each turbine nozzle outer band aft flange is directed at an oblique discharge angle towards the leading edge of the at least one turbine shroud segment, and channeling the cooling fluid through at least a first group of cooling openings having a larger aggregate cross-sectional area and a second group of cooling openings having a smaller aggregate cross-sectional area to facilitate preferential cooling of the turbine shroud.
FILED Thursday, November 30, 2006
APPL NO 11/565273
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611619 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Yi Zhang (Evanston, Illinois);  Khalid Salaita (Evanston, Illinois)
ABSTRACT The invention provides a simple and convenient strategy for reducing the dimensions of organic micro- and nanostructures on metal surfaces. By varying electrochemical desorption conditions, organic structures patterned by Dip-Pen Nanolithography or any of the micro-contact printing procedures can be gradually desorbed in a controlled fashion. The electrochemical desorption is initiated at the exterior of the feature and moves inward as a function of time. The desorption process and adsorbate desorption are modified and controlled as a function of substrate morphology, adsorbate head and tail groups, and electrolyte solvent and salt. Different nanostructures made of different adsorbates can be miniaturized based upon judicious selection of adsorbate and supporting electrolyte.
FILED Monday, July 07, 2003
APPL NO 10/520554
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/640
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611625 Hazlebeck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armaments Center (CCDC AC)
APPLICANT(S)
ASSIGNEE(S) General Atomics (San Diego, California)
INVENTOR(S) David A. Hazlebeck (El Cajon, California);  John L. Perlman (San Diego, California)
ABSTRACT A system and method for oxidizing a feed material includes a reactor vessel that forms an enclosed chamber. The vessel includes a port for introducing the feed material into the chamber where it can be oxidized to create salts and particulates, together with a fluid effluent. After their creation, the salts and particulates flow into a brine pool maintained within the chamber. Thereafter, brine, including salts and particulates, can be removed from the chamber through a vessel outlet. Further, the vessel includes a fluid effluent discharge pipe extending from outside the vessel, through the brine pool, into the chamber. As a result of this structure, the fluid effluent can be separated from the salts and particulates and discharged from the chamber through the pipe, passing through the brine pool.
FILED Wednesday, April 12, 2006
APPL NO 11/279522
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Liquid purification or separation
210/179
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611661 Villalobos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Guillermo R. Villalobos (Springfield, Virginia);  Jas S. Sanghera (Ashburn, Virginia);  Shyam S. Bayya (Ashburn, Virginia);  Ishwar D. Aggarwal (Fairfax Station, Virginia)
ABSTRACT This invention pertains to product and process. The product is a transparent product of a density in excess 99.5% comprising spinel and having uniform mechanical properties. The process pertains to fabrication of a transparent spinel product comprising the steps of dissolving a sintering aid in water to form a neutral sintering aid solution, adding a suitable additive to the sintering aid solution, applying the sintering aid solution to spinel particles to form a spinel dispersion, sub-dividing or atomizing the spinel dispersion to form droplets comprising one or more spinel particles coated with the final spinel solution, drying the droplets to form dried coated particles comprising one or more spinel particles coated with a dried layer of the sintering aid, and densifying the dried coated particles to form a transparent spinel product having, uniform optical and mechanical properties in absence of grains of exaggerated size.
FILED Thursday, March 24, 2005
APPL NO 11/094543
ART UNIT 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/681
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US 07611858 Svetlov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Stanislav Svetlov (Gainesville, Florida);  Ronald L. Hayes (Gainesville, Florida);  Ka-Wang (Kevin) Wang (Gainesville, Florida)
ABSTRACT Traumatic insult to the brain leads to a degradation of low molecular weight of cannabinoid type 1 receptor (CB1) and generation of high molecular weight complexes in the cortex and hippocampus, as assessed by both N-terminal and C-terminal specific antibodies. The formation and release of CB1 oligomers was dramatically increased into CSF within 1 hour following traumatic brain insult. Novel CB1 receptor-based, prognostic markers of traumatic brain injury and other forms of brain injury are disclosed. A method of repopulating damaged neural cells by proliferation of a subgroup of neural progenitor cells is described. Targeting CB1 receptors for therapeutic neuroprotection in TBI is also disclosed.
FILED Friday, April 20, 2007
APPL NO 11/738159
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.950
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611866 Georgiou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Multidisciplinary University Research Initiative (MURI)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) George Georgiou (Austin, Texas);  Ki Jun Jeong (Austin, Texas);  Barrett R. Harvey (Souderton, Pennsylvania);  Brent L. Iverson (Austin, Texas)
ABSTRACT The invention overcomes the deficiencies of the prior art by providing a rapid approach for isolating polypeptides capable of anchoring heterologous polypeptides to a bacterial inner membrane. In the technique, libraries of candidate anchor polypeptides are expressed as fusions with a heterologous polypeptide that is capable of being detected when bound to the inner membrane. In bacteria expressing a functional anchor sequence, the heterologous polypeptide becomes bound to outer face of the inner membrane. Bacteria with the functional anchor sequence can be identified by removing the outer membrane to remove non-anchored heterologous polypeptide followed by detection of anchored heterologous polypeptide. Such bacteria may be detected in numerous ways, including use of direct fluorescence or secondary antibodies that are fluorescently labeled, allowing use of efficient techniques such as fluorescence activated cell sorting (FACS).
FILED Friday, March 18, 2005
APPL NO 11/084717
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611896 Martin
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Samuel K. Martin (Nairobi, Kenya)
ABSTRACT Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detection of antibodies to Leishmania parasite soluble antigens and antigen-capture ELISAs for the detection of Leishmania parasite soluble antigens in host samples. Also disclosed are immunodiagnostic kits for the detection of Leishmania parasite circulating antigens or IgM and IgG antibodies in a sample from subject having visceral, cutaneous or canine leishmaniasis. In these methods and kits, detection may be done photometrically or visually. The methods and kits also allow the visualization of Leishmania amastigotes or promastigotes in a sample.
FILED Monday, June 13, 2005
APPL NO 11/150322
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/404
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US 07611911 Abraham et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David William Abraham (Croton-on-Hudson, New York);  Eugene John O'Sullivan (Nyack, New York)
ABSTRACT A method (and resulting structure) of patterning a magnetic thin film, includes using a chemical transformation of a portion of the magnetic thin film to transform the portion to be non-magnetic and electrically insulating.
FILED Wednesday, October 08, 2003
APPL NO 10/680260
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/3
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US 07611969 Chu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Houston (Houston, Texas)
INVENTOR(S) Ching-Wu Chu (Houston, Texas);  Feng Chen (Houston, Texas);  Yu-Yi Xue (Houston, Texas);  Jason Shulman (Houston, Texas);  Stephen Tsui (Houston, Texas)
ABSTRACT A negative dielectric is induced by the application of a dc bias-electric field in aggregates of oxide nano-particles whose surfaces have been specially treated. The magnitude of the dielectric constant and the frequency where the negative dielectric constant occurs can be adjusted. Such material systems have profound implications in novel devices as well as in science development, e.g. unusual wave propagation, secured communication and ultra-high temperature superconductivity.
FILED Friday, February 17, 2006
APPL NO 11/356767
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/466
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US 07612085 Mach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Robert H. Mach (Eureka, Missouri);  Zhude Tu (Eureka, Missouri);  Wenhua Chu (St. Louis, Missouri);  Suwanna Vangveravong (Ballwin, Missouri);  Richard Hotchkiss (Chesterfield, Missouri);  William Hawkins (Olivette, Missouri);  Rebecca Aft (Chesterfield, Missouri)
ABSTRACT A series of N-substituted 9-azabicyclo[3.3.1]nonan-3α-yl phenylcarbamate analogs are disclosed, as well as methods of their preparation. Their affinities for sigma (σ1 and σ2) receptors are described. Two new compounds, N-(9-(4-aminobutyl)-9-azabicyclo[3.3.1]nonan-3α-yl)-N′-(2-methoxy-5-methylphenyl)carbamate and N-(9-(6-aminohexyl)-9-azabicyclo[3.3.1]nonan-3α-yl)-N′-(2-methoxy-5-methylphenyl)carbamate, are shown to have a high affinity and selectivity for σ2 versus σ1 receptors. Among the disclosed compounds are biotinylated and fluorescent analogs. These compounds can serve as probes to the σ2 receptor. In addition, some disclosed compounds can induce apoptotic cell death by both caspase-dependent and caspase-independent mechanisms, and are effective for treatment of tumors. The compounds can be used as chemotherapeutics or chemosensitizers in the treatment of a wide variety of solid tumors.
FILED Wednesday, July 11, 2007
APPL NO 11/776533
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/299
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612152 Braun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Paul V. Braun (Savoy, Illinois);  Soo Hyoun Cho (Champaign, Illinois);  Scott R. White (Champaign, Illinois);  Nancy R. Sottos (Champaign, Illinois);  H. Magnus Andersson (Champaign, Illinois)
ABSTRACT A composite material includes a polymer matrix, a polymerizer, and a plurality of capsules containing a corresponding activator for the polymerizer. The composite material can also include an adhesion promoter, and the polymerizer can be phase separated from the polymer matrix. The composite material can be made by dispersing the polymerizer and capsules into the polymer matrix. These composite materials can exhibit improved environmental stability, and can be used with a wider variety of activators.
FILED Friday, May 06, 2005
APPL NO 11/123859
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
525/476
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US 07612170 Punnonen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Maxygen, Inc. (Redwood City, California)
INVENTOR(S) Juha Punnonen (Belmont, California);  Alexandra L. L. Lazetic (San Jose, California);  Steven R. Leong (Berkeley, California);  Jean Chia-Chun Chang (Los Gatos, California)
ABSTRACT The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability of the polypeptides to preferentially bind a CD28 or CTLA-4 receptor at a level greater or less than the ability of human B7-1 to bind CD28 or CTLA-4, or to induce or inhibit altered level of T cell proliferation response greater compared to that generated by human B7-1. The polypeptides and polynucleotides of the invention are useful in therapeutic and prophylactic treatment methods, gene therapy applications, and vaccines.
FILED Friday, January 13, 2006
APPL NO 11/332037
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
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US 07612184 Seeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Nadrian Seeman (New York, New York);  Hao Yan (Durham, North Carolina);  Xiaoping Zhang (Woodside, New York);  Zhiyong Shen (Fremont, California)
ABSTRACT The present invention is directed to a sequence dependent polynucleotide nanomechanical device based on a nucleic acid paranemic crossover (PX) molecule which is a four-stranded structure related to parallel double crossover molecules, except that every possible crossover takes place. Eliminating two crossovers leads to a topoisomer, termed JX2, in which one pair of ends are switched (rotated 180°) while the other pair of ends remain the same. The device can be cycled between the two states, PX and JX2, by replacing single strands that set the state to be PX or JX2.
FILED Friday, February 21, 2003
APPL NO 10/370101
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
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US 07612206 Mach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Robert Mach (Eureka, Missouri);  Michael J. Welch (Clayton, Missouri);  Douglas J. Rowland (Davis, California);  Zhude Tu (Frontenac, Missouri)
ABSTRACT Novel benzamide compounds of Formula (I), Formula (II), and Formula (III), salts, water soluble salts, analogs and radiolabeled counterparts thereof as sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors. A method for diagnosing a mammal for the presence of a mammalian tumor therein comprises administering to the mammal a diagnostic imaging detectable effective amount of a benzamide compound having a structure illustrated in Formula (I), Formula (II) and Formula (III) and detecting binding of the compound to a tumor in the mammal. A method for diagnostic imaging of a mammalian tissue having cell surface sigma-2 receptors comprising administering to a mammal a diagnostic imaging amount of a compound having a structure illustrated in Formula (I) Formula (II) and Formula (III) and detecting an image of a tissue having an ample cells with sigma-2 receptors.
FILED Saturday, March 08, 2008
APPL NO 12/044952
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612290 Le
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) Wiliams - Pyro, Inc. (Fort Worth, Texas)
INVENTOR(S) Kevin D. Le (Richland Hills, Texas)
ABSTRACT A flexible high speed micro-cable and method of making the same are described. The parallel conductors incorporated in the present cable contribute to the flat cross section of the cable, while the unique combination of materials yield a flexible cable with a low profile. The data transfer rate and transmission losses of a cable, as provided herein, exceed High Speed Universal Serial Bus (USB) 2.0 specifications and data transmission is achieved from USB devices. The lower volume and mass of the cable make it ideal for applications needing low mass payload, such as satellites. The flexible nature of the cable allow it to readily conform to a desired structure for mounting or routing. A flexible high speed micro-cable is fabricated from a unique combination of materials and fabrication can be readily automated.
FILED Wednesday, June 04, 2008
APPL NO 12/132989
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Conductors and insulators
174/117.F00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612317 Chalfant, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Space Photonics, Inc. (Fayetteville, Arkansas)
INVENTOR(S) Charles H. Chalfant, III (Fayetteville, Arkansas);  Fred J. Orlando (West Melbourne, Florida);  Jeffrey T. Gregory (Mountainburg, Arkansas);  Chad B. O'Neal (Ruston, Louisiana);  Terry L. Tidwell (Fayetteville, Arkansas)
ABSTRACT A targeting and tracking apparatus and method for optical transceivers is disclosed. The tracking function is performed internally by way of translating an internal optical fiber in the focal plane of the transceiver telescope using miniature motorized translation systems and/or micro-electro-mechanical systems (MEMS). The optical design of the transceiver provides a wide field of view and a pointing and tracking field of regard that is directly proportional to the translation of the optical fiber in the focal plane of the telescope. The apparatus and method can eliminate the need for external gimballing systems and scanning mirrors, and replace the gimballed optical beam steering function with motorized translation systems and/or MEMS that consumes very little power.
FILED Monday, September 12, 2005
APPL NO 11/224628
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/203.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612324 Payton et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) David Payton (Calabasas, California);  Mike Daily (Thousand Oaks, California);  Mike Howard (Westlake Village, California);  Craig Lee (Redondo Beach, California)
ABSTRACT An apparatus configured to obtain, process, and relay data to a user in a coherent and useful manner. An active fiducial is equipped with an interface for receiving and transmitting data. The fiducial may transmit its position using a satellite-based position sensing device such as a GPS. Active fiducials may also be equipped with battery power pack regenerated with solar cells. Similarly, the fiducials can be equipped with at least one video camera or other device having a focal plane array and a computer software system, configured to recognize shapes. The fiducials may also be equipped with inductive coils or other means for sensing metal containing compounds. The active fiducials may be equipped with a gas chromatograph. The active fiducials may use a variety of propulsion means including motor driven tracks, motor driven wheels, propellers, or other device or a combination of devices.
FILED Monday, March 14, 2005
APPL NO 11/080053
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/221
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612329 Chalfant, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Space Photonics, Inc. (Fayetteville, Arkansas)
INVENTOR(S) Charles H. Chalfant, III (Fayetteville, Arkansas);  Fred J. Orlando (West Melbourne, Florida);  Jeffrey T. Gregory (Mountainburg, Arkansas);  Chad B. O'Neal (Ruston, Louisiana)
ABSTRACT A beam steering apparatus and method for free space optical transceivers is disclosed. The beam steering function is performed internally by way of translating an internal optical fiber in the focal plane of the transceiver telescope using miniature micro-electro-mechanical systems (MEMS). The optical design of the transceiver provides a wide field of view and a pointing and tracking field of regard that is directly proportional to the translation of the optical fiber in the focal plane of the telescope. The apparatus and method can eliminate the need for external gimballing systems, and replace the gimballed free space optical beam steering function with MEMS that consumes very little power.
FILED Monday, September 12, 2005
APPL NO 11/224745
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/234
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US 07612390 Saxler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Adam William Saxler (Durham, North Carolina);  Yifeng Wu (Goleta, California);  Primit Parikh (Goleta, California)
ABSTRACT A heterojunction transistor may include a channel layer comprising a Group III nitride, a barrier layer comprising a Group III nitride on the channel layer, and an energy barrier comprising a layer of a Group III nitride including indium on the channel layer such that the channel layer is between the barrier layer and the energy barrier. The barrier layer may have a bandgap greater than a bandgap of the channel layer, and a concentration of indium (In) in the energy barrier may be greater than a concentration of indium (In) in the channel layer. Related methods are also discussed.
FILED Friday, February 17, 2006
APPL NO 11/357752
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/194
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612540 Singh
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Harmohan N. Singh (Rockaway, New Jersey)
ABSTRACT Embodiments provide a method and a system for determining cell imbalance condition of a multi-cell battery including a plurality of cell strings. To determine a cell imbalance condition, a charge current is applied to the battery and is monitored during charging. The charging time for each cell string is determined based on the monitor of the charge current. A charge time difference of any two cell strings in the battery is used to determine the cell imbalance condition by comparing with a predetermined acceptable charge time difference for the cell strings.
FILED Tuesday, October 24, 2006
APPL NO 11/552287
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Battery or capacitor charging or discharging
320/162
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US 07612729 Horner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Rob Horner (San Diego, California);  Rod Cozad (San Diego, California);  Hale Simonds (San Diego, California);  Robbi Mangra (San Diego, California)
ABSTRACT A VHTR TSA For Impedance Matching Method (NC#098835). The method includes providing a first antenna element of a tapered slot antenna pair, providing a second antenna element of the tapered slot antenna pair and operatively coupling the first antenna element and the second antenna element to form the tapered slot antenna pair having a gap height and a TSA thickness having a correlation represented by the following equation: h = w × z 0 × e r 44 × π ;
where h=gap height w=TSA thickness z0=characteristic impedance er=dielectric constant of dielectric spacing material V=a constant having a value greater than or equal to 15 and less than or equal to 100. π=ratio of a circle's circumference to its diameter.
FILED Thursday, August 23, 2007
APPL NO 11/843841
ART UNIT 2821 — Printing/Measuring and Testing
CURRENT CPC
Communications: Radio wave antennas
343/767
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612731 Peterson
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Lewis Peterson (La Habra, California)
ABSTRACT Methods and apparatus for a plate to prevent energy from a first antenna from interfering with a collocated second antenna. In one embodiment, the plate includes first and second conductive layers to shadow the second antenna and thereby block energy from reaching the second antenna. A resonant quarter wavelength spacing of the plates forces energy broadside minimizing the spillover the edge caused by diffraction. Multiple conductive layers having increasing radii can block diffracted energy from spilling over and around the plate. The multiple plates of increasing radii affect a waterfall-like spill wherein energy is lost in each level.
FILED Friday, March 30, 2007
APPL NO 11/693971
ART UNIT 2821 — Printing/Measuring and Testing
CURRENT CPC
Communications: Radio wave antennas
343/841
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US 07612775 Goyne et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Linda J Goyne (Florissant, Missouri);  Ken L Bernier (O'Fallon, Missouri);  Jeremy D Childress (Saint Peters, Missouri)
ABSTRACT A method for rendering a real-time conformal view of terrestrial body's terrain being traversed by a mobile platform includes storing digital terrain elevation data (DTED) tiles for at least a portion of the terrain of a terrestrial body into an external removable mass data storage device (ERMDSD). The ERMDSD is connectable to an onboard computer system (OCS) comprising embedded mobile platform components that include at least one processing card, at least random access memory (RAM) device and at least one graphics card. The method additionally includes executing a real-time rendering assist application (RTRAA) stored in the processing card to dynamically repackage the DTED tiles into DTED chunks being representative of an area of the terrestrial body to be traversed (ATBT) by the mobile platform. The method further includes executing the RTRAA to create a base mesh of root diamonds representative of the ATBT and tessellate the root diamonds to create a plurality of leaf diamonds. Further yet the method includes utilizing the graphics card only to render the leaf diamonds, thereby generating a realtime conformal view of the ATBT.
FILED Thursday, July 28, 2005
APPL NO 11/191621
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/423
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612869 Pereira et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) California Institute Of Technology (Pasadena, California)
INVENTOR(S) Francisco Pereira (Pasadena, California);  Darius Modarress (Rancho Palos Verdes, California);  Mory Gharib (San Marino, California);  Dana Dabiri (Altadena, California);  David Jeon (Los Angeles, California)
ABSTRACT A system and method for determining instantaneously the three-dimensional coordinates of large sets of points in space is disclosed. This system uses two or more CCD cameras (or any other type of camera), each with its own lens and pinhole. The CCD's are all arranged so that the pixel arrays are within the same plane. The CCD's are also arranged in a predefined pattern. The combination of the multiple images acquired from the CCD's onto one single image forms a pattern, which is dictated by the predefined arrangement of the CCD's. The size and centroid on the combined image are a direct measure of the depth location Z and in-plane position (X,Y), respectively. The use of a predefined pattern enables high speed computation through simple algorithmic procedures. Moreover, the use of CCD cameras allows for the recording of such datasets at the corresponding image frame rate, thus opening the use of the invention to the mapping of dynamical systems.
FILED Tuesday, February 28, 2006
APPL NO 11/365970
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/3.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612870 Graff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) California Institute Of Technology (Pasadena, California)
INVENTOR(S) Emilio Castano Graff (Pasadena, California);  Francisco Pereira (Pasadena, California);  Morteza Gharib (San Marino, California);  Michele Milano (Tempe, Arizona)
ABSTRACT Determining instantaneously three-dimensional coordinates of large sets of points in space using apertures associated with cameras or camera parts. An embodiment associates information from the apertures with different portions of the imager, so that portions on the imager do not overlap.
FILED Thursday, September 14, 2006
APPL NO 11/522500
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/3.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612876 Widen
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Kenneth C. Widen (Topanga, California)
ABSTRACT A measure of the quality of a laser beam is obtained by comparing the power of a theoretical Gaussian beam through a (certain sized area) pinhole to the power of a test beam through a same sized (area) pinhole. The theoretical surrogate Gaussian beam with the same second moment of intensity as the test beam is used to determine the “bucket size” used in “power-in-the-bucket” techniques. The bucket size is an interaction area determined by the wavelength of the laser light, the focusing distance, and the 1/e2 radius of the near field intensity. The beam quality is determined by taking the square root of the ratio of the theoretical power through a bucket and the actual power through a pinhole with the same size as the bucket. The beam quality of different types of beam profiles can be obtained with a single method or measure.
FILED Thursday, May 29, 2008
APPL NO 12/129019
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/121
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US 07613074 Blackmon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Fletcher A. Blackmon (Forestdale, Massachusetts);  Lee E. Estes (Mattapoisett, Massachusetts);  Gilbert Fain (East Freetown, Massachusetts);  Lynn T. Antonelli (Cranston, Rhode Island)
ABSTRACT The present invention includes a system and method of use for communications from an in-air platform to a submerged platform. The system includes a laser positionable on the in-air platform above a water medium that sends a pulsed information-bearing laser beam containing a modulated communications signal to create and react in a non-linear regime manner with the water medium at an air/water interface. The beam vaporizes and optically breaks down a portion of the water medium, creates a shock wave and generates bubble oscillations at the vaporized portion. An acoustic sensor on the submerged platform detects these shock wave oscillations within the water medium and a demodulator-decoder that identifies these broadband acoustic transients that contain deterministically placed energy and demodulates-decodes the acoustic transients into the transmitted communications signals from the in-air platform.
FILED Tuesday, January 03, 2006
APPL NO 11/326679
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/134
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613075 Cray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin A. Cray (West Kingston, Rhode Island);  Walter H. Boober (Newport, Rhode Island);  Stephen E. Forsythe (Portsmouth, Rhode Island);  Lee E. Estes (Mattapoisett, Massachusetts);  Andrew J. Hull (Portsmouth, Rhode Island)
ABSTRACT An acoustic sensing device includes a housing having an internal cavity filled with a vibration decoupling medium. An acoustic window formed of an acoustically transparent material is mounted in the housing. This mounting can be by antivibration mounts to prevent housing noise from affecting the acoustic window. A scanning laser vibrometer is positioned within the housing and directed to detect vibrations of the acoustic window. Antivibration mounts are joined between said scanning laser vibrometer and said housing. In further embodiments, the scanning laser vibrometer detects vibrations at a plurality of locations on the acoustic window forming a virtual array.
FILED Tuesday, June 12, 2007
APPL NO 11/761536
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/149
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613309 Jones et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Douglas L. Jones (Champaign, Illinois);  Michael E. Lockwood (Champaign, Illinois);  Robert C. Bilger (Champaign, Illinois);  Carolyn T. Bilger, legal representative (Champaign, Illinois);  Albert S. Feng (Champaign, Illinois);  Charissa R. Lansing (Champaign, Illinois);  William D. O'Brien (Champaign, Illinois);  Bruce C. Wheeler (Champaign, Illinois);  Mark Elledge (Austin, Texas);  Chen Liu (Lisle, Illinois)
ABSTRACT System (10) is disclosed including an acoustic sensor array (20) coupled to processor (42). System (10) processes inputs from array (20) to extract a desired acoustic signal through the suppression of interfering signals. The extraction/suppression is performed by modifying the array (20) inputs in the frequency domain with weights selected to minimize variance of the resulting output signal while maintaining unity gain of signals received in the direction of the desired acoustic signal. System (10) may be utilized in hearing aids, voice input devices, surveillance devices, and other applications.
FILED Thursday, November 07, 2002
APPL NO 10/290137
ART UNIT 2614 — Semiconductors/Memory
CURRENT CPC
Electrical audio signal processing systems and devices
381/94.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613323 Nister et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Sarnoff Corporation (Princeton, New Jersey)
INVENTOR(S) David Nister (Lexington, Kentucky);  James Bergen (Hopewell, New Jersey)
ABSTRACT A method and apparatus for determining camera pose characterized by six degrees of freedom (e.g., for use in computer vision systems) is disclosed. In one embodiment an image captured by the camera is received, and at least two constraints on the potential pose are enforced in accordance with known relations of the image to the camera, such that the potential pose is constrained to two remaining degrees of freedom. At least one potential pose is then determined in accordance with the remaining two degrees of freedom.
FILED Wednesday, June 22, 2005
APPL NO 11/159967
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613509 Wolf et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Patrick D. Wolf (Durham, North Carolina);  Iyad Obeid (Brussels, Belgium)
ABSTRACT Systems, Methods, and Computer Program Products for Transmitting Neural Signal Information. Systems, method, and computer program products are provided for neural signal transmission. A system according to one embodiment can include a signal receiver operable to receive a neural signal comprising an action potential. The system can also include an action potential detector operable to communicate with the signal receiver and detect when the action potential occurs. In addition, the system can include a transmitter in communication with the action potential detector and operable to transmit an information signal indicating the time when the action potential occurs and, in addition, can transmit samples associated with a detected action potential.
FILED Monday, November 29, 2004
APPL NO 10/998385
ART UNIT 3766 — Selective Visual Display Systems
CURRENT CPC
Surgery
6/545
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US 07613553 Benjamin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael R. Benjamin (Boston, Massachusetts)
ABSTRACT A method for autonomously controlling a vehicle includes establishing decision variables for maneuvering the vehicle. Behavior functions are established for behaviors of the vehicle as a function of at least one of the established decision variables. These behavior function give a score which may be weighted, indicating the desirability of engaging in the associated behavior. A summation of the weighted behavior functions can be solved while the vehicle is operating to determine the values of the decision variables giving the highest summation of scores. In a preferred method, an optimal structure for the behavior functions and summation solution is taught. The method then guides the vehicle in accordance with the determined decision variable values.
FILED Friday, July 30, 2004
APPL NO 10/911765
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/26
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613579 Haddad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Darren Haddad (Frankfort, New York);  Andrew J. Noga (Rome, New York)
ABSTRACT The invention disclosed herein provides a method and apparatus for analyzing periodic signals so as to determine the degree of harmonicity in real time. Harmonicity estimates are generated for each segment of a signal without the need to process subsequent segments. Harmonicity estimates can be generated in the absence of a fundamental frequency component. The invention has utility in the audio/speech domain for automated speaker identification.
FILED Thursday, November 08, 2007
APPL NO 11/998990
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/66
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613761 Hou
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Hsieh S. Hou (Rancho Palos Verdes, California)
ABSTRACT A shared lossless Haar transform and an appended discrete cosine transform type-II are combined to form a discrete cosine type-II transform in a parallel pipelined architecture for providing lossless data transformation.
FILED Monday, June 27, 2005
APPL NO 11/168978
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers: Arithmetic processing and calculating
78/402
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613803 Pioso
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Bennett G. Pioso (Clifton, Virginia)
ABSTRACT The MIST provides a mechanism to dynamically determine and characterize the status of distributed objects that communicate in a complex, multiple sub-system, and systems integration environment. At run time, objects that should be participating in the environment are determined. A static database or dynamic learning mechanism is used to characterize the platform's interface graph. The status of event channels and servers, and their corresponding interfaces, are continuously determined and depicted. Status is graphically displayed by using various filtering, a circular interface display, and 2-D graph displays to allow a user to rapidly identify the occurrence, source, and impact of system interface faults.
FILED Monday, June 09, 2003
APPL NO 10/456560
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/224
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613848 Amini et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lisa D. Amini (Yorktown Heights, New York);  Anshul Sehgal (New York, New York);  Jeremy I. Silber (New York, New York);  Olivier Verscheure (Hopewell Junction, New York)
ABSTRACT Disclosed are a method, upstream processing node, and computer readable medium for dynamically stabilizing a stream processing system. The method includes receiving at least one computing resource allocation target. The method further includes determining that an input data flow rate of at least one upstream processing element varies. The computing resource is dynamically allocated to the upstream processing element in response to the input rate of the upstream processing element varying. Data flow is dynamically controlled between the upstream processing element and at least one downstream processing element.
FILED Tuesday, June 13, 2006
APPL NO 11/451947
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital data processing systems: Input/output
710/29
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US 07614021 Allen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jeffery C. Allen (San Diego, California)
ABSTRACT A method of determining an amplifier performance is provided. One embodiment establishes a number of amplifier performance constraints. A search is then conducted for an input and an output disk that satisfy the amplifier performance constraints. A vector index is then generated that includes a load reflectance SL and a generator reflectance SG at a number of different radio frequencies. The amplifier performance constraints are then input into the vector index and the load reflectances SL and generator reflectances SG that meet the amplifier performance constraints are determined.
FILED Tuesday, May 22, 2007
APPL NO 11/752034
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/1
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07611508 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Deshan Yang (Madison, Wisconsin);  John Michael Bertram (Fridley, Minnesota);  Mark Christopher Converse (Cottage Grove, Wisconsin);  John Goodwin Webster (Madison, Wisconsin);  David Mahvi (Middleton, Wisconsin)
ABSTRACT An antenna for microwave tumor ablation provides coaxial antenna conductors surrounded by an insulated sleeve of length and size promoting destructive interference of axial microwave energy passing inside and outside of the sleeve to limit the tail of SAR power toward the skin.
FILED Tuesday, August 23, 2005
APPL NO 11/210063
ART UNIT 3739 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Surgery
66/33
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611673 Kartalov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Emil Kartalov (Pasadena, California);  Axel Scherer (Laguna Beach, California);  W. French Anderson (San Gabriel, California)
ABSTRACT Component microfluidic devices which are integrated with polydimethylsiloxane (PDMS) microfluidic chips, include designs for an electrical and optical pressure gauge, valve, electrostatic and magnetic pumps, alternating or mixing pumps, a solenoid, a magnetometer, a magnetically actuated reversible filter and valve, and a hydrolysis valve. These devices enhance and miniaturize microfluidic control, thereby expanding the available capabilities and allowing complete system miniaturization for handheld diagnostic apparatuses.
FILED Thursday, September 28, 2006
APPL NO 11/529130
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611713 Sette et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Pharmexa Inc. (San Diego, California)
INVENTOR(S) Alessandro Sette (La Jolla, California);  John Sidney (San Diego, California);  Scott Southwood (Santee, California);  Maria Vitiello (La Jolla, California);  Brian Livingston (San Diego, California);  Esteban Celis (Rochester, Minnesota);  Ralph Kubo (Carlsbad, California);  Howard Grey (La Jolla, California);  Robert Chesnut (Cardiff-by-the-Sea, California)
ABSTRACT This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.
FILED Thursday, September 04, 2003
APPL NO 10/654601
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/189.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611833 Ahlquist et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Paul G. Ahlquist (Madison, Wisconsin);  Masayuki Ishikawa (Sapporo, Japan);  Juana Diez (Barcelona, Spain);  Duane B. Price (Mountain Brook, Alabama);  Wai-Ming Lee (Madison, Wisconsin)
ABSTRACT An antiviral agent comprising an altered MAB1, MAB2, MAB3, or OLE1 gene, gene homologs or related genes is disclosed. In another embodiment, the present invention is a method of creating a virus resistant organism comprising creating a transgenic organism comprising an antiviral agent selected from the group of altered MAB1 genes, MAB2 genes, MAB3 genes or OLE1 genes, homologs of these genes, related genes and combinations of these genes and homologs.
FILED Monday, July 14, 2003
APPL NO 10/618896
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611838 Harbison et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Christopher T. Harbison (Hamilton, New Jersey);  Richard A. Young (Weston, Massachusetts);  David B. Gordon (Somerville, Massachusetts);  Ernest Fraenkel (Cambridge, Massachusetts)
ABSTRACT The invention relates to the identification of biologically-active DNA-binding sites to which a protein of interest binds in a cell. The invention also relates to the identification of agents and conditions which alter the biologically-active DNA-binding sites to which a protein binds. One aspect of the invention also provides methods for identifying pathways that are regulated by transcriptional regulators and for modulating the activity of the pathways.
FILED Thursday, March 03, 2005
APPL NO 10/591271
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611843 Felden
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Brice Felden (Le Lou du Lac, France)
ABSTRACT The present invention is directed to eubacterial tmDNA sequences and the corresponding tmRNA sequences. The present invention is further directed to alignments of eubacterial tmDNA sequences and the use of the sequences and sequence alignments for the development of antibacterial drugs. The present invention is also directed to the use of the sequences for the development of diagnostic assays.
FILED Wednesday, January 11, 2006
APPL NO 11/329230
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611844 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California)
INVENTOR(S) Ken Y. Lin (Boston, Massachusetts);  John Cooke (Palo Alto, California)
ABSTRACT The present invention provides methods of detecting asymmetric dimethylarginine (ADMA) in a sample, particularly a sample that may contain symmetrical dimethylarginine (SDMA) and/or arginine. The methods generally involve modifying any SDMA and arginine in the sample such that SDMA and arginine are readily distinguishable from ADMA; and detecting ADMA. The invention further provides antibodies specific for ADMA; antibodies specific for modified SDMA; and antibodies specific for modified arginine. The invention further provides kits for practicing the subject methods.
FILED Thursday, November 13, 2003
APPL NO 10/713674
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611852 Thomson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) James A. Thomson (Madison, Wisconsin);  Timothy J. Kamp (Madison, Wisconsin);  Yue Ma (Madison, Wisconsin);  Jia-Qiang He (Madison, Wisconsin)
ABSTRACT Human embryonic stem cells form embryoid bodies in culture which contain differentiated human cells. Some of the human cells in embryoid bodies differentiate into cardiomyocytes. Here the biological and electrical characteristics of those cardiomyocytes are described with reference to the use of cardiomyocytes derived from human embryonic stem cells in drug screening protocols for mechanisms of cardiac toxicity.
FILED Friday, July 25, 2003
APPL NO 10/627245
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611858 Svetlov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Stanislav Svetlov (Gainesville, Florida);  Ronald L. Hayes (Gainesville, Florida);  Ka-Wang (Kevin) Wang (Gainesville, Florida)
ABSTRACT Traumatic insult to the brain leads to a degradation of low molecular weight of cannabinoid type 1 receptor (CB1) and generation of high molecular weight complexes in the cortex and hippocampus, as assessed by both N-terminal and C-terminal specific antibodies. The formation and release of CB1 oligomers was dramatically increased into CSF within 1 hour following traumatic brain insult. Novel CB1 receptor-based, prognostic markers of traumatic brain injury and other forms of brain injury are disclosed. A method of repopulating damaged neural cells by proliferation of a subgroup of neural progenitor cells is described. Targeting CB1 receptors for therapeutic neuroprotection in TBI is also disclosed.
FILED Friday, April 20, 2007
APPL NO 11/738159
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.950
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611870 Feinberg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University School of Medicine (Baltimore, Maryland)
INVENTOR(S) Andrew P. Feinberg (Lutherville, Maryland)
ABSTRACT The present invention provides methods and kits for identifying an increased risk of developing cancer in a subject. The methods include analyzing a first biological sample, such as a blood sample, from the subject for loss of imprinting of the IGF2 gene. According to the methods a loss of imprinting is indicative of an increased risk of developing cancer. The method can include analyzing genomic DNA from the sample for altered methylation of the IGF2 gene. The altered methylation for example includes hypomethylation of a differentially methylated region of IGF2, corresponding to SEQ ID NO:1 or a polymorphism thereof. The method can be performed on a subject having no apparent or suspected hyperproliferative disorder such as cancer.
FILED Friday, January 03, 2003
APPL NO 10/336552
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611910 Balin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Intracell, LLC (Merion, Pennsylvania)
INVENTOR(S) Brian J. Balin (Paoli, Pennsylvania);  J. Todd Abrams (Merion, Pennsylvania);  Alan P. Hudson (Novi, Michigan);  Judith A. Whittum-Hudson (Novi, Michigan)
ABSTRACT The invention relates to a method of treating Alzheimer's disease in a mammal comprising administering to the mammal an anti-microbial agent having anti-Chlamydia pneumoniae activity. The invention also relates to a method of diagnosing Alzheimer's disease in a mammal comprising measuring the serum anti-Chlamydia pneumoniae antibody titer in a patient suspected of having Alzheimer's disease.
FILED Friday, January 12, 2007
APPL NO 11/622641
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/811
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612039 Khalili
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Temple University - Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Kamel Khalili (Merion, Pennsylvania)
ABSTRACT The growth of normal and abnormally proliferating cells can be inhibited by the introduction of agnoprotein, or biologically active fragments or derivatives of agnoprotein, into the cell in the absence of any other polyoma virus protein or viral replication.
FILED Wednesday, June 11, 2003
APPL NO 10/517710
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612042 Maihle et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Tumor Biology Investment Group, Inc. (Lexington, Kentucky)
INVENTOR(S) Nita J. Maihle (New Haven, Connecticut);  Lee Hakjoo (Pittsford, New York)
ABSTRACT The present invention discloses a method using human soluble ErbB3, for example p85-sErbB3, as a negative regulator of heregulin-stimulated ErbB2, ErbB3, and ErbB4 activation. The present invention also discloses p85-sErbB3 binding to heregulin with an affinity comparable to that of full-length ErbB3, and competitively inhibiting high affinity heregulin binding to ErbB2/ErbB3 heterodimers on the cell surface of breast carcinoma cells. The present invention also uses p85-sErbB3 to inhibit heregulin-induced phosphorylation of ErbB2, ErbB3, and ErbB4 in cells, as a negative regulator of heregulin-stimulated signal transduction, and as a block for cell growth. The present invention is also directed to nucleic acids and expression vectors encoding p85-sErbB3, host cells harboring such expression vectors, and methods of producing the protein. The present invention discloses a method of therapeutically treating human malignancies associated with heregulin-mediated cell growth such as breast and prostate cancer.
FILED Wednesday, January 23, 2008
APPL NO 12/018610
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612044 Kawakami et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Yutaka Kawakami (Kanagawa, Japan);  Steven A. Rosenberg (Potomac, Maryland)
ABSTRACT The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the MART-1 melanoma antigen and a second melanoma antigen designated gp100. This invention further provides immunogenic peptides derived from the MART-1 melanoma antigen or gp100 antigen which have been modified to enhance their immunogenicity. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma.
FILED Monday, May 21, 2007
APPL NO 11/751233
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612071 Kamen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Syntrix Biosystems, Inc. (Auburn, Washington)
INVENTOR(S) Barton Aron Kamen (Princeton Junction, New Jersey);  Peter David Cole (Montclair, New Jersey);  Angela King Smith (West Windsor, New Jersey);  John Anthony Zebala (Sammamish, Washington)
ABSTRACT The present invention relates to pharmaceutical compositions containing the antifolate aminopterin, processes for making the compositions, and methods of using them to treat disorders in adult and pediatric patients. Pharmaceutical compositions substantially free of impurities are provided comprising a therapeutically effective amount of aminopterin, or a pharmaceutically acceptable salt thereof. Relative to the teachings of the prior art, the disclosed methods and compositions provide unexpected improvements that include a greater interpatient oral bioavailability in pediatric patients, a smaller interpatient coefficient of variation of oral bioavailability, a smaller mean intrapatient coefficient of variation of oral bioavailability, a greater therapeutic index, a smaller coefficient of variation of toxicity, efficacy in combination therapy, and efficacy of certain polyglutamated metabolites.
FILED Wednesday, March 09, 2005
APPL NO 11/078614
ART UNIT 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/249
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612080 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cincinnati Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) Yi Zheng (Cincinnati, Ohio);  Huzoor Akbar (Athens, Ohio);  David A. Williams (Cincinnati, Ohio);  Wieslaw Adam Mazur (Mason, Ohio)
ABSTRACT The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.
FILED Friday, November 18, 2005
APPL NO 11/283556
ART UNIT 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/275
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612085 Mach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Robert H. Mach (Eureka, Missouri);  Zhude Tu (Eureka, Missouri);  Wenhua Chu (St. Louis, Missouri);  Suwanna Vangveravong (Ballwin, Missouri);  Richard Hotchkiss (Chesterfield, Missouri);  William Hawkins (Olivette, Missouri);  Rebecca Aft (Chesterfield, Missouri)
ABSTRACT A series of N-substituted 9-azabicyclo[3.3.1]nonan-3α-yl phenylcarbamate analogs are disclosed, as well as methods of their preparation. Their affinities for sigma (σ1 and σ2) receptors are described. Two new compounds, N-(9-(4-aminobutyl)-9-azabicyclo[3.3.1]nonan-3α-yl)-N′-(2-methoxy-5-methylphenyl)carbamate and N-(9-(6-aminohexyl)-9-azabicyclo[3.3.1]nonan-3α-yl)-N′-(2-methoxy-5-methylphenyl)carbamate, are shown to have a high affinity and selectivity for σ2 versus σ1 receptors. Among the disclosed compounds are biotinylated and fluorescent analogs. These compounds can serve as probes to the σ2 receptor. In addition, some disclosed compounds can induce apoptotic cell death by both caspase-dependent and caspase-independent mechanisms, and are effective for treatment of tumors. The compounds can be used as chemotherapeutics or chemosensitizers in the treatment of a wide variety of solid tumors.
FILED Wednesday, July 11, 2007
APPL NO 11/776533
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/299
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612166 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Trustees of Tufts College (Boston, Massachusetts)
INVENTOR(S) Krishna Kumar (Cambridge, Massachusetts);  Vittorio Montanari (Somerville, Massachusetts)
ABSTRACT Aspects of the present invention relate to compounds for preparing fluorocarbon compounds, methods for preparing fluorocarbon compounds, and methods for purifying a mixture of compounds. One aspect of the present invention relates to a trivalent iodonium fluorocarbon. The trivalent iodonium fluorocarbon compound of the invention is useful for attaching a fluorocarbon group to a compound that has a nucleophilic functional group. Another aspect of the present invention relates to a method of preparing a trivalent iodonium fluorocarbon. Another aspect of the present invention relates to a method of preparing a fluorocarbon by treating a compound bearing a nucleophilic functional group with a trivalent iodonium fluorocarbon compound. Another aspect of the present invention relates to a method or purifying a mixture comprising a first and a second compound by treating the mixture with a trivalent iodonium fluorocarbon to attach a fluorocarbon group to the second compound leaving the first compound unchanged, and purifying the mixture by fluorous-phase purification.
FILED Wednesday, May 18, 2005
APPL NO 11/597067
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/344
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612167 Sharma et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Arun Sharma (Oak Park, Illinois);  Ronald Hoffman (Chicago, Illinois)
ABSTRACT The present invention relates to novel human hiwi protein and genes that encode such proteins. The invention is directed toward the isolation and characterization of human hiwi proteins. The invention specifically provides isolated complementary DNA copies of mRNA corresponding to a human hiwi gene. Also provided are recombinant expression constructs capable of expressing the human hiwi gene of the invention in cultures of transformed prokaryotic and eukaryotic cells, as well as such cultures of transformed cells that synthesize the human hiwi proteins encoded therein. The invention also provides methods for isolating human hematopoietic stem cells.
FILED Tuesday, May 31, 2005
APPL NO 11/141072
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612171 Friedman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Jeffrey M. Friedman (New York, New York);  Gwo-Hwa Lee (New York, New York);  Ricardo Proenca (Astoria, New York)
ABSTRACT The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In particular, the present invention relates to identification and characterization of the receptor for leptin, including a naturally occurring soluble form of the receptor that is expected to modulate leptin activity, in particular to agonize leptin activity. The invention further relates to the nucleic acids encoding the receptor, and to methods for using the receptor, e.g., to identify leptin analogs, therapeutically, such as in gene therapy or in soluble form as an agonist or antagonist of leptin activity, or diagnostically.
FILED Thursday, March 16, 2006
APPL NO 11/377486
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612184 Seeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Nadrian Seeman (New York, New York);  Hao Yan (Durham, North Carolina);  Xiaoping Zhang (Woodside, New York);  Zhiyong Shen (Fremont, California)
ABSTRACT The present invention is directed to a sequence dependent polynucleotide nanomechanical device based on a nucleic acid paranemic crossover (PX) molecule which is a four-stranded structure related to parallel double crossover molecules, except that every possible crossover takes place. Eliminating two crossovers leads to a topoisomer, termed JX2, in which one pair of ends are switched (rotated 180°) while the other pair of ends remain the same. The device can be cycled between the two states, PX and JX2, by replacing single strands that set the state to be PX or JX2.
FILED Friday, February 21, 2003
APPL NO 10/370101
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612186 Roosild et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Tarmo Roosild (Las Vegas, Nevada);  Jason Greenwald (Zurich, Switzerland);  Senyon Choe (Solana Beach, California);  Roland Riek (Zurich, Switzerland)
ABSTRACT A class of integral membrane proteins, referred to as Mistic polypeptides, their variants, fusion proteins including a Mistic polypeptide domain, and nucleic acid molecules encoding Mistic polypeptides and Mistic fusion proteins are disclosed herein. Also described are methods of using Mistic polypeptides and Mistic fusion proteins to produce and/or isolate recombinant proteins (including without limitation classes of eukaryotic proteins that have previously been intractable to recombinant bacterial expression, such as, eukaryotic integral membrane proteins).
FILED Thursday, December 22, 2005
APPL NO 11/317847
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612188 Nelsestuen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Saint Paul, Minnesota)
INVENTOR(S) Gary L Nelsestuen (St. Paul, Minnesota)
ABSTRACT The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.
FILED Thursday, November 02, 2006
APPL NO 11/555769
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612189 Hancock et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) GE Healthcare UK Limited (Amersham, United Kingdom);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Suzanne Hancock (Cardiff, United Kingdom);  Simon Stubbs (Cardiff, United Kingdom);  Nicholas Thomas (Cardiff, United Kingdom);  Ellen Fanning (Nashville, Tennessee);  Jinming Gu (Boston, Massachusetts)
ABSTRACT The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.
FILED Friday, July 22, 2005
APPL NO 11/572510
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612197 Beaucage et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as repesented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Serge L Beaucage (Silver Spring, Maryland);  Marcin K Chmielewski (Poznan, Poland)
ABSTRACT Provided is a hydroxyl-protected alcohol comprising a thermolabile hydroxyl-protecting group comprising a 2-pyridyl substituent and a precursor of the thermolabile hydroxyl-protected alcohol. An exemplary thermolabile hydroxyl-protected alcohol is represented by the formula Pg-O—R, wherein Pg is a protecting group of the formula: (Formula) wherein: A is a 2-pyridyl; Z is CH2 or NR1; R1, R2, R2′, R3 and R3′ are the same or different and each can be, e.g., H, alkyl, or alkyl comprising an aryl substituent; W is CO, CS, or SO; and R is the organic residue of the hydroxyl-protected alcohol. Also provided is a method of producing an alcohol, which method comprises heating the hydroxyl-protected alcohol, which optionally may be obtained from a precursor, at a temperature effective to cleave the hydroxyl-protecting group. The method can be used to produce oligonucleotides.
FILED Friday, May 07, 2004
APPL NO 10/556219
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/25.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612206 Mach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Robert Mach (Eureka, Missouri);  Michael J. Welch (Clayton, Missouri);  Douglas J. Rowland (Davis, California);  Zhude Tu (Frontenac, Missouri)
ABSTRACT Novel benzamide compounds of Formula (I), Formula (II), and Formula (III), salts, water soluble salts, analogs and radiolabeled counterparts thereof as sigma-2 receptor radiotracers for imaging the proliferative status of solid tumors. A method for diagnosing a mammal for the presence of a mammalian tumor therein comprises administering to the mammal a diagnostic imaging detectable effective amount of a benzamide compound having a structure illustrated in Formula (I), Formula (II) and Formula (III) and detecting binding of the compound to a tumor in the mammal. A method for diagnostic imaging of a mammalian tissue having cell surface sigma-2 receptors comprising administering to a mammal a diagnostic imaging amount of a compound having a structure illustrated in Formula (I) Formula (II) and Formula (III) and detecting an image of a tissue having an ample cells with sigma-2 receptors.
FILED Saturday, March 08, 2008
APPL NO 12/044952
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613309 Jones et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Douglas L. Jones (Champaign, Illinois);  Michael E. Lockwood (Champaign, Illinois);  Robert C. Bilger (Champaign, Illinois);  Carolyn T. Bilger, legal representative (Champaign, Illinois);  Albert S. Feng (Champaign, Illinois);  Charissa R. Lansing (Champaign, Illinois);  William D. O'Brien (Champaign, Illinois);  Bruce C. Wheeler (Champaign, Illinois);  Mark Elledge (Austin, Texas);  Chen Liu (Lisle, Illinois)
ABSTRACT System (10) is disclosed including an acoustic sensor array (20) coupled to processor (42). System (10) processes inputs from array (20) to extract a desired acoustic signal through the suppression of interfering signals. The extraction/suppression is performed by modifying the array (20) inputs in the frequency domain with weights selected to minimize variance of the resulting output signal while maintaining unity gain of signals received in the direction of the desired acoustic signal. System (10) may be utilized in hearing aids, voice input devices, surveillance devices, and other applications.
FILED Thursday, November 07, 2002
APPL NO 10/290137
ART UNIT 2614 — Semiconductors/Memory
CURRENT CPC
Electrical audio signal processing systems and devices
381/94.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613335 McLennan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Geoffrey McLennan (Iowa City, Iowa);  Martin Donnelley (Blackwood, Australia);  Deepa Gopalakrishnan (San Diego, California);  Eric Hoffman (Iowa City, Iowa);  Joseph Reinhardt (Iowa City, Iowa);  Melissa Suter (Iowa City, Iowa)
ABSTRACT In one embodiment, a method that includes comparing a subject color medical image to normal color medical image data; and identifying abnormal pixels from the subject color medical image. Another embodiment includes a computer readable medium comprising machine readable instructions for implementing one or more steps of that method. Another embodiment includes a device that has a field programmable gate array configured to perform one or more of the steps of that method. Another embodiment includes a device that has an application specific integrated circuit configured to perform one or more of the steps of that method.
FILED Thursday, February 12, 2004
APPL NO 10/777764
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613494 Hadley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) J. Rock Hadley (Centerville, Utah);  Dennis Parker (Centerville, Utah);  Aaron J. Burnett (Bountiful, Utah)
ABSTRACT The present invention includes a system that allows for the easy substitution of imaging elements attached to an anatomical positioning device. One or more imaging elements may be mounted to the anatomical positioning device in such a way that the placement of the imaging elements in relation to the anatomical positioning device and the subject can be easily controlled by the operator.
FILED Friday, November 26, 2004
APPL NO 10/998189
ART UNIT 3768 — Selective Visual Display Systems
CURRENT CPC
Surgery
6/407
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07610775 Tonkovich et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Velocys, Inc. (Plain City, Ohio)
INVENTOR(S) Anna Lee Tonkovich (Dublin, Ohio);  Wayne W. Simmons (Dublin, Ohio);  Laura J. Silva (Dublin, Ohio);  Dongming Qiu (Carbondale, Illinois);  Steven T. Perry (Galloway, Ohio);  Thomas Yuschak (Dublin, Ohio);  Thomas P. Hickey (Dublin, Ohio);  Ravi Arora (Dublin, Ohio);  Amanda Smith (Galloway, Ohio);  Robert Dwayne Litt (Westerville, Ohio);  Paul Neagle (Westerville, Ohio)
ABSTRACT The disclosed invention relates to a distillation process for separating two or more components having different volatilities from a liquid mixture containing the components. The process employs microchannel technology for effecting the distillation and is particularly suitable for conducting difficult separations, such as the separation of ethane from ethylene, wherein the individual components are characterized by having volatilities that are very close to one another.
FILED Friday, July 08, 2005
APPL NO 11/177941
ART UNIT 3744 — SELECT * FROM codes_techcenter;
CURRENT CPC
Refrigeration
062/617
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07610962 Fowler
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Shell Oil Company (Houston, Texas)
INVENTOR(S) Thomas David Fowler (Houston, Texas)
ABSTRACT Systems, methods, and heaters for treating a subsurface formation are described herein. At least one method for providing acidic gas to a subsurface formation is described herein. The method may include providing heat from one or more heaters to a portion of a subsurface formation; producing fluids that include one or more acidic gases from the formation using a heat treatment process. At least a portion of one of the acidic gases may be introduced into the formation, or into another formation, through one or more wellbores at a pressure below a lithostatic pressure of the formation in which the acidic gas is introduced.
FILED Friday, April 20, 2007
APPL NO 11/788864
ART UNIT 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Wells
166/267
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611524 Maitland et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Duncan J. Maitland (Pleasant Hill, California);  Ward Small, IV (Livermore, California);  Jonathan Hartman (Sacramento, California)
ABSTRACT A flexible extension for a shape memory polymer occlusion removal device. A shape memory polymer instrument is transported through a vessel via a catheter. A flexible elongated unit is operatively connected to the distal end of the shape memory polymer instrument to enhance maneuverability through tortuous paths en route to the occlusion.
FILED Tuesday, September 27, 2005
APPL NO 11/238018
ART UNIT 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
66/157
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611565 Paglieri et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Stephen N. Paglieri (White Rock, New Mexico);  Iver E. Anderson (Ames, Iowa);  Robert L. Terpstra (Ames, Iowa)
ABSTRACT A device for hydrogen separation has a porous support and hydrogen separation material on the support. The support is prepared by heat treatment of metal microparticles, preferably of iron-based or nickel-based alloys that also include aluminum and/or yttrium. The hydrogen separation material is then deposited on the support. Preferred hydrogen separation materials include metals such as palladium, alloys, platinum, refractory metals, and alloys.
FILED Monday, October 16, 2006
APPL NO 11/581981
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Gas separation: Processes
095/56
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US 07611573 Bhattacharya
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Raghu N. Bhattacharya (Littleton, Colorado)
ABSTRACT The invention provides CBD ZnS/Zn(O,OH)S and spray deposited ZnS/Zn(O,OH)S buffer layers prepared from a solution of zinc salt, thiourea and ammonium hydroxide dissolved in a non-aqueous/aqueous solvent mixture or in 100% non-aqueous solvent. Non-aqueous solvents useful in the invention include methanol, isopropanol and triethyl-amine. One-step deposition procedures are described for CIS, CIGS and other solar cell devices.
FILED Friday, April 02, 2004
APPL NO 10/592963
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions: Coating or plastic
16/286.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611834 Chhabra et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Livermore, California)
INVENTOR(S) Swapnil Chhabra (San Jose, California);  José´ M. Cintrón (Indianapolis, Indiana);  Renée Shediac (Oakland, California)
ABSTRACT Methods and devices for protein assays based on Edman degradation in microfluidic channels are disclosed herein. As disclosed, the cleaved amino acid residues may be immobilized in an array format and identified by detectable labels, such as antibodies, which specifically bind given amino acid residues. Alternatively, the antibodies are immobilized in an array format and the cleaved amino acids are labeled identified by being bound by the antibodies in the array.
FILED Friday, September 30, 2005
APPL NO 11/239387
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611835 Kim et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jungbae Kim (Richland, Washington);  Ja Hun Kwak (Richland, Washington);  Jay W. Grate (West Richland, Washington)
ABSTRACT A process for preparing high stability, high activity biocatalytic materials is disclosed and processes for using the same. The process involves coating of a material or fiber with enzymes and enzyme aggregate providing a material or fiber with high biocatalytic activity and stability useful in heterogeneous environments. In one illustrative approach, enzyme “seeds” are covalently attached to polymer nanofibers followed by treatment with a reagent that crosslinks additional enzyme molecules to the seed enzymes forming enzyme aggregates thereby improving biocatalytic activity due to increased enzyme loading and enzyme stability. This approach creates a useful new biocatalytic immobilized enzyme system with potential applications in bioconversion, bioremediation, biosensors, and biofuel cells.
FILED Friday, September 30, 2005
APPL NO 11/241506
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611856 Schmidt et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Jurgen G. Schmidt (Los Alamos, New Mexico);  Anne E. Boyer (Atlanta, Georgia);  Suzanne R. Kalb (Atlanta, Georgia);  Hercules Moura (Tucker, Georgia);  John R. Barr (Suwannee, Georgia);  Adrian R. Woolfitt (Atlanta, Georgia)
ABSTRACT The present invention is directed to a method for detecting the presence of clostridial neurotoxins in a sample by mixing a sample with a peptide that can serve as a substrate for proteolytic activity of a clostridial neurotoxin; and measuring for proteolytic activity of a clostridial neurotoxin by a mass spectroscopy technique. In one embodiment, the peptide can have an affinity tag attached at two or more sites.
FILED Wednesday, November 03, 2004
APPL NO 10/980346
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.720
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611878 Kim et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jungbae Kim (Richland, Washington);  Ja Hun Kwak (Richland, Washington);  Jay W. Grate (West Richland, Washington)
ABSTRACT The present invention relates generally to high stability, high activity biocatalytic materials and processes for using the same. The materials comprise enzyme aggregate coatings having high biocatalytic activity and stability useful in heterogeneous environment. These new materials provide a new biocatalytic immobilized enzyme system with applications in bioconversion, bioremediation, biosensors, and biofuel cells.
FILED Friday, September 30, 2005
APPL NO 11/251540
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/174
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611903 Vogel et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) John S. Vogel (San Jose, California);  Ted J. Ognibene (Oakland, California);  Graham S. Bench (Livermore, California);  Graham F. Peaslee (Holland, Michigan)
ABSTRACT A system for quantitatively reducing oxide gases. A pre-selected amount of zinc is provided in a vial. A tube is provided in the vial. The zinc and the tube are separated. A pre-selected amount of a catalyst is provided in the tube. Oxide gases are injected into the vial. The vial, tube, zinc, catalyst, and the oxide gases are cryogenically cooled. At least a portion of the vial, tube, zinc, catalyst, and oxide gases are heated.
FILED Wednesday, September 11, 2002
APPL NO 10/241301
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/177
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612185 Lu et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Yi Lu (Champaign, Illinois);  Juewen Liu (Urbana, Illinois)
ABSTRACT Sensors comprising aptazymes capable of detecting the presence and concentration of effectors, as well as methods of using such sensors, are disclosed.
FILED Friday, March 07, 2003
APPL NO 10/384497
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612541 Brainard et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) John P. Brainard (Albuquerque, New Mexico);  Todd R. Christenson (Albuquerque, New Mexico)
ABSTRACT A charge-pump voltage converter for converting a low voltage provided by a low-voltage source to a higher voltage. Charge is inductively generated on a transfer rotor electrode during its transit past an inductor stator electrode and subsequently transferred by the rotating rotor to a collector stator electrode for storage or use. Repetition of the charge transfer process leads to a build-up of voltage on a charge-receiving device. Connection of multiple charge-pump voltage converters in series can generate higher voltages, and connection of multiple charge-pump voltage converters in parallel can generate higher currents. Microelectromechanical (MEMS) embodiments of this invention provide a small and compact high-voltage (several hundred V) voltage source starting with a few-V initial voltage source. The microscale size of many embodiments of this invention make it ideally suited for MEMS- and other micro-applications where integration of the voltage or charge source in a small package is highly desirable.
FILED Tuesday, August 07, 2007
APPL NO 11/835046
ART UNIT 2839 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Single generator systems
322/2.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612896 Stone
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Gary Franklin Stone (Livermore, California)
ABSTRACT A method of measuring the three-dimensional volume or perimeter shape of an interior cavity includes the steps of collecting a first optical slice of data that represents a partial volume or perimeter shape of the interior cavity, collecting additional optical slices of data that represents a partial volume or perimeter shape of the interior cavity, and combining the first optical slice of data and the additional optical slices of data to calculate of the three-dimensional volume or perimeter shape of the interior cavity.
FILED Tuesday, September 02, 2008
APPL NO 12/202569
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/627
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612937 Jorgensen et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Gary J. Jorgensen (Pine, Colorado);  Randy Gee (Arvada, Colorado)
ABSTRACT A silver mirror construction that maintains a high percentage of hemispherical reflectance throughout the UV and visible spectrum when used in solar reflectors, comprising: a) a pressure sensitive adhesive layer positioned beneath a silver overlay; b) a polymer film disposed on the silver overlay; c) an adhesive layer positioned on the polymer film; and d) a UV screening acrylic film disposed on the adhesive layer.
FILED Friday, December 16, 2005
APPL NO 11/303836
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/361
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07611619 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Yi Zhang (Evanston, Illinois);  Khalid Salaita (Evanston, Illinois)
ABSTRACT The invention provides a simple and convenient strategy for reducing the dimensions of organic micro- and nanostructures on metal surfaces. By varying electrochemical desorption conditions, organic structures patterned by Dip-Pen Nanolithography or any of the micro-contact printing procedures can be gradually desorbed in a controlled fashion. The electrochemical desorption is initiated at the exterior of the feature and moves inward as a function of time. The desorption process and adsorbate desorption are modified and controlled as a function of substrate morphology, adsorbate head and tail groups, and electrolyte solvent and salt. Different nanostructures made of different adsorbates can be miniaturized based upon judicious selection of adsorbate and supporting electrolyte.
FILED Monday, July 07, 2003
APPL NO 10/520554
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/640
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611833 Ahlquist et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Paul G. Ahlquist (Madison, Wisconsin);  Masayuki Ishikawa (Sapporo, Japan);  Juana Diez (Barcelona, Spain);  Duane B. Price (Mountain Brook, Alabama);  Wai-Ming Lee (Madison, Wisconsin)
ABSTRACT An antiviral agent comprising an altered MAB1, MAB2, MAB3, or OLE1 gene, gene homologs or related genes is disclosed. In another embodiment, the present invention is a method of creating a virus resistant organism comprising creating a transgenic organism comprising an antiviral agent selected from the group of altered MAB1 genes, MAB2 genes, MAB3 genes or OLE1 genes, homologs of these genes, related genes and combinations of these genes and homologs.
FILED Monday, July 14, 2003
APPL NO 10/618896
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611969 Chu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Houston (Houston, Texas)
INVENTOR(S) Ching-Wu Chu (Houston, Texas);  Feng Chen (Houston, Texas);  Yu-Yi Xue (Houston, Texas);  Jason Shulman (Houston, Texas);  Stephen Tsui (Houston, Texas)
ABSTRACT A negative dielectric is induced by the application of a dc bias-electric field in aggregates of oxide nano-particles whose surfaces have been specially treated. The magnitude of the dielectric constant and the frequency where the negative dielectric constant occurs can be adjusted. Such material systems have profound implications in novel devices as well as in science development, e.g. unusual wave propagation, secured communication and ultra-high temperature superconductivity.
FILED Friday, February 17, 2006
APPL NO 11/356767
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/466
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612057 Brewer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S) Karen Brewer (Blacksburg, Virginia);  Shawn Swavey (Kettering, Ohio)
ABSTRACT The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging π-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
FILED Wednesday, July 20, 2005
APPL NO 11/184840
ART UNIT 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/188
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612166 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) Trustees of Tufts College (Boston, Massachusetts)
INVENTOR(S) Krishna Kumar (Cambridge, Massachusetts);  Vittorio Montanari (Somerville, Massachusetts)
ABSTRACT Aspects of the present invention relate to compounds for preparing fluorocarbon compounds, methods for preparing fluorocarbon compounds, and methods for purifying a mixture of compounds. One aspect of the present invention relates to a trivalent iodonium fluorocarbon. The trivalent iodonium fluorocarbon compound of the invention is useful for attaching a fluorocarbon group to a compound that has a nucleophilic functional group. Another aspect of the present invention relates to a method of preparing a trivalent iodonium fluorocarbon. Another aspect of the present invention relates to a method of preparing a fluorocarbon by treating a compound bearing a nucleophilic functional group with a trivalent iodonium fluorocarbon compound. Another aspect of the present invention relates to a method or purifying a mixture comprising a first and a second compound by treating the mixture with a trivalent iodonium fluorocarbon to attach a fluorocarbon group to the second compound leaving the first compound unchanged, and purifying the mixture by fluorous-phase purification.
FILED Wednesday, May 18, 2005
APPL NO 11/597067
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/344
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612184 Seeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Nadrian Seeman (New York, New York);  Hao Yan (Durham, North Carolina);  Xiaoping Zhang (Woodside, New York);  Zhiyong Shen (Fremont, California)
ABSTRACT The present invention is directed to a sequence dependent polynucleotide nanomechanical device based on a nucleic acid paranemic crossover (PX) molecule which is a four-stranded structure related to parallel double crossover molecules, except that every possible crossover takes place. Eliminating two crossovers leads to a topoisomer, termed JX2, in which one pair of ends are switched (rotated 180°) while the other pair of ends remain the same. The device can be cycled between the two states, PX and JX2, by replacing single strands that set the state to be PX or JX2.
FILED Friday, February 21, 2003
APPL NO 10/370101
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612185 Lu et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Yi Lu (Champaign, Illinois);  Juewen Liu (Urbana, Illinois)
ABSTRACT Sensors comprising aptazymes capable of detecting the presence and concentration of effectors, as well as methods of using such sensors, are disclosed.
FILED Friday, March 07, 2003
APPL NO 10/384497
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612424 Espinosa et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Horacio D. Espinosa (Winnetka, Illinois);  Changhong Ke (Evanston, Illinois)
ABSTRACT Nano-electromechanical device having an electrically conductive nano-cantilever wherein the nano-cantilever has a free end that is movable relative to an electrically conductive substrate such as an electrode of a circuit. The circuit includes a power source connected to the electrode and to the nano-cantilever for providing a pull-in or pull-out voltage therebetween to effect bending movement of the nano-cantilever relative to the electrode. Feedback control is provided for varying the voltage between the electrode and the nano-cantilever in response to the position of the cantilever relative to the electrode. The device provides two stable positions of the nano-cantilever and a hysteresis loop in the current-voltage space between the pull-in voltage and the pull-out voltage. A first stable position of the nano-cantilever is provided at sub-nanometer gap between the free end of the nano-cantilever and the electrode with a pull-in voltage applied and with a stable tunneling electrical current present in the circuit. A second stable position of the nano-cantilever is provided with a pull-out voltage between the cantilever and the electrode with little or no tunneling electrical current present in the circuit. The nano-electromechanical device can be used in a scanning probe microscope, ultrasonic wave detection sensor, NEMS switch, random access memory element, gap sensor, logic device, and a bio-sensor when the nano-cantilever is functionalized with biomolecules that interact with species present in the ambient environment be them in air or aqueous solutions. In the latest case, the NEMS needs to be integrated with a microfluidic system.
FILED Tuesday, March 21, 2006
APPL NO 11/385970
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/415
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612985 Dementiev et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Viacheslav V. Dementiev (Madison, Wisconsin);  Robert C. West (Madison, Wisconsin);  Robert J. Hamers (Madison, Wisconsin);  Kiu-Yuen Tse (Madison, Wisconsin)
ABSTRACT Disclosed are supercapacitors having organosilicon electrolytes, high surface area/porous electrodes, and optionally organosilicon separators. Electrodes are formed from high surface area material (such as porous carbon nanotubes or carbon nanofibers), which has been impregnated with the electrolyte. These type devices appear particularly suitable for use in electric and hybrid electric vehicles.
FILED Monday, July 07, 2008
APPL NO 12/168405
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/502
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613214 Sanders
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Scott Thomas Sanders (Madison, Wisconsin)
ABSTRACT A mode-locked laser employs a light-wavelength-dependent, path-length adjuster to provide different path-lengths for multiple light frequencies and dual modulation frequencies selecting multiple modes with different wavelengths. The result is a single cavity laser producing mode-locked light outputs at defined different frequencies. Tuning of each frequency may be obtained by changing the laser modulation frequencies.
FILED Wednesday, May 16, 2007
APPL NO 11/749553
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/18
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07611862 Ponce
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Adrian Ponce (Pasadena, California)
ABSTRACT A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the test surface comprises lanthanide ions. Aromatic molecules are released from the bacterial spores; a complex of the lanthanide ions and aromatic molecules is formed on the test surface, the complex is excited to generate a characteristic luminescence on the test surface; the luminescence on the test surface is detected and quantified.
FILED Thursday, January 12, 2006
APPL NO 11/332788
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/34
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612355 Wu et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ming Chiang Wu (Orinda, California);  Pei Yu Chiou (Los Angeles, California);  Aaron T. Ohta (Berkeley, California)
ABSTRACT An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 μm or less. The apparatus is referred to as optoelectric tweezers (OET) and provides a number of advantages over conventional optical tweezers, in particular the ability to perform operations in parallel and over a large area without damage to living cells. The OET device generally comprises a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a change in the electric field pattern. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells. The OET preferably includes a microscopic imaging means to provide feedback for the optical manipulation, such as detecting position and characteristics wherein the light patterns are modulated accordingly.
FILED Tuesday, April 12, 2005
APPL NO 11/105304
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/559.40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612462 Viterna
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Larry A. Viterna (Olmsted Falls, Ohio)
ABSTRACT A floating wind turbine system with a tower structure that includes at least one stability arm extending therefrom and that is anchored to the sea floor with a rotatable position retention device that facilitates deep water installations. Variable buoyancy for the wind turbine system is provided by buoyancy chambers that are integral to the tower itself as well as the stability arm. Pumps are included for adjusting the buoyancy as an aid in system transport, installation, repair and removal. The wind turbine rotor is located downwind of the tower structure to allow the wind turbine to follow the wind direction without an active yaw drive system. The support tower and stability arm structure is designed to balance tension in the tether with buoyancy, gravity and wind forces in such a way that the top of the support tower leans downwind, providing a large clearance between the support tower and the rotor blade tips. This large clearance facilitates the use of articulated rotor hubs to reduced damaging structural dynamic loads. Major components of the turbine can be assembled at the shore and transported to an offshore installation site.
FILED Thursday, April 24, 2008
APPL NO 12/150072
ART UNIT 2839 — Semiconductors/Memory
CURRENT CPC
Prime-mover dynamo plants
290/53
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07612221 Haas et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Michael J. Haas (Oreland, Pennsylvania);  William N. Marmer (Fort Washington, Pennsylvania);  Thomas A. Foglia (Lafayette Hill, Pennsylvania)
ABSTRACT The present invention relates to a method for producing fatty acid alkyl esters, involving transesterifying a feedstock containing lipid-linked fatty acids with an alcohol and an alkaline catalyst to form fatty acid alkyl esters. The feedstock has not been previously treated to release the lipid components of said feedstock, or the feedstock has been previously treated to release lipid components and the feedstock contains residual lipids (e.g., <about 30% of the original content of lipids).
FILED Monday, January 23, 2006
APPL NO 11/337458
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
554/174
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612250 Overstrom et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Eric W. Overstrom (Grafton, Massachusetts);  Daniela Fischer Russell (Guelph, Canada)
ABSTRACT A nuclear transfer embryo is formed by destabilizing microtubules of an oocyte, whereby essentially all endogenous chromatin collects at a second polar body during meiosis of an oocyte. The oocyte is fused with the nucleus of a donor somatic cell of the same species of said oocyte prior to cessation of extrusion of the second polar body from the oocyte, thereby forming the nuclear transfer embryo. In one embodiment, the nuclear transfer embryo is employed to impregnate an animal, such as a mammal. In another embodiment, the donor nucleus is transgenic.
FILED Monday, July 29, 2002
APPL NO 10/208653
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/24
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07611914 Fitz et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S) John L. Fitz (Baltimore, Maryland);  Daniel S. Hinkel (Sykesville, Maryland);  Scott C. Horst (Sykesville, Maryland)
ABSTRACT The present invention is a method of fabricating a waveguide using a sacrificial spacer layer. The first step in this process is to fabricate the underlying optical semiconductor structure. A trench is then etched in this structure resulting in an underlying L-shaped structure. A sacrificial spacer layer is deposited in the trench. The waveguide is created in the trench on the sacrificial spacer layer using a mask layer to angle the vertex of the L-shaped structure. User-defined portions of the sacrificial spacer layer are subsequently removed to create air gaps between the waveguide and the sidewalls of the trench in the optical semiconductor.
FILED Friday, June 16, 2006
APPL NO 11/472225
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/22
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07613848 Amini et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lisa D. Amini (Yorktown Heights, New York);  Anshul Sehgal (New York, New York);  Jeremy I. Silber (New York, New York);  Olivier Verscheure (Hopewell Junction, New York)
ABSTRACT Disclosed are a method, upstream processing node, and computer readable medium for dynamically stabilizing a stream processing system. The method includes receiving at least one computing resource allocation target. The method further includes determining that an input data flow rate of at least one upstream processing element varies. The computing resource is dynamically allocated to the upstream processing element in response to the input rate of the upstream processing element varying. Data flow is dynamically controlled between the upstream processing element and at least one downstream processing element.
FILED Tuesday, June 13, 2006
APPL NO 11/451947
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital data processing systems: Input/output
710/29
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07612374 Wu et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S) Yiliang Wu (Mississauga, Canada);  Yuning Li (Mississauga, Canada);  Beng S Ong (Singapore, Singapore)
ABSTRACT A thin film transistor comprising: (a) an insulating layer; (b) a gate electrode; (c) a semiconductor layer; (d) a source electrode; and (e) a drain electrode, wherein the insulating layer, the gate electrode, the semiconductor layer, the source electrode, and the drain electrode are in any sequence as long as the gate electrode and the semiconductor layer both contact the insulating layer, and the source electrode and the drain electrode both contact the semiconductor layer, and wherein at least one of the source electrode, the drain electrode, and the gate electrode comprise coalesced coinage metal containing nanoparticles and a residual amount of one or both of a stabilizer covalently bonded to the coalesced coinage metal containing nanoparticles and a decomposed stabilizer covalently bonded to the coalesced coinage metal containing nanoparticles.
FILED Wednesday, December 12, 2007
APPL NO 11/954736
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/60
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07610791 Kwun et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S) Southwest Research Institute (San Antonio, Texas)
INVENTOR(S) Hegeon Kwun (San Antonio, Texas);  Ronald H. Peterson (Helotes, Texas)
ABSTRACT Systems and methods are described that carry out an intelligent, variable, time-gain control (TGC) of signal amplification in a long-range, guided-wave inspection and monitoring system. The systems and methods compensate for signal attenuation over the longer distances that guided-wave inspection techniques are capable of operating with. The sensor signal received is divided into relevant frequency bands that are each subjected to a variable TGC through separate variable gain amplifiers (VGAs). The gain selection is processor controlled through the use of a digital look-up table (LUT) stored with predetermined gain functions and/or data that are both time and frequency specific. The signal components are re-combined and digitized for further signal analysis and defect detection. The LUT is established through one or more methods including a weld signal amplitude equalization approach and a background noise equalization approach.
FILED Thursday, March 08, 2007
APPL NO 11/715655
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/1.820
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07611612 Nair et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S)
ASSIGNEE(S) Ceramatec, Inc. (Salt Lake City, Utah)
INVENTOR(S) Balakrishnan G. Nair (Sandy, Utah);  Jesse Nachlas (Salt Lake City, Utah)
ABSTRACT A mixed potential NOx sensor apparatus for measuring the total NOx concentration in a gas stream is disclosed. The NOx sensing apparatus comprises a multilayer ceramic structure with electrodes for sensing both oxygen and NOx gas concentrations and includes screen-printed metalized patterns that function to heat the ceramic sensing element to the proper temperature for optimum performance. This design may provide advantages over the existing technology by miniaturizing the sensing element to provide potentially faster sensor light off times and thereby reduce undesired exhaust gas emissions. By incorporating the heating source within the ceramic sensing structure, the time to reach the temperature of operation is shortened, and thermal gradients and stresses are minimized. These improvements may provide increased sensor performance, reliability, and lifetime.
FILED Thursday, July 14, 2005
APPL NO 11/182278
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical and wave energy
24/426
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 07612731 Peterson
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Lewis Peterson (La Habra, California)
ABSTRACT Methods and apparatus for a plate to prevent energy from a first antenna from interfering with a collocated second antenna. In one embodiment, the plate includes first and second conductive layers to shadow the second antenna and thereby block energy from reaching the second antenna. A resonant quarter wavelength spacing of the plates forces energy broadside minimizing the spillover the edge caused by diffraction. Multiple conductive layers having increasing radii can block diffracted energy from spilling over and around the plate. The multiple plates of increasing radii affect a waterfall-like spill wherein energy is lost in each level.
FILED Friday, March 30, 2007
APPL NO 11/693971
ART UNIT 2821 — Printing/Measuring and Testing
CURRENT CPC
Communications: Radio wave antennas
343/841
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. Agency for International Development (USAID) 

US 07612043 Gonzalez et al.
FUNDED BY
U.S. Agency for International Development (USAID)
APPLICANT(S)
ASSIGNEE(S) Boston Biomedical Research Institute (Watertown, Massachusetts)
INVENTOR(S) Ruben Rene Gonzalez (Watertown, Massachusetts);  Paul C. Leavis (Epping, New Hampshire)
ABSTRACT Disclosed herein are peptides comprising a leptin sequence and methods for their use in preventing ObR signaling in a leptin-responsive cell. A leptin peptide of the present invention binds to but does not activate ObR signaling in a leptin-responsive cell, thereby inhibiting the up-regulatory effects of leptin on ObR signaling in the leptin-responsive cell. Administration of the peptide effectively prevents embryo implantation in a mammal to which the peptide has been administered. Also disclosed herein is a method for identifying a peptide antagonist of ObR, wherein the peptide comprises a leptin sequence.
FILED Friday, June 06, 2008
APPL NO 12/157127
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07613617 Williams et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) David E. Williams (Stafford, Virginia);  Stephen J. McElroy (Manassas, Virginia)
ABSTRACT Systems and methods for managing powered industrial vehicles are provided. In one embodiment, the system includes an analyzer module configured to determine route data based on facility layout data. The system also includes a dispatch management module configured to receive a request to transport cargo from a first location to a second location in the warehouse, and a surface visibility module configured to track the cargo after it is transferred from the first location to the second location by receiving scanned barcode data from the cargo via a scanner connected to a wireless network.
FILED Wednesday, May 03, 2006
APPL NO 11/417007
ART UNIT 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/1
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07611830 Thatte et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Veteran's Affairs (Washington, District of Columbia)
INVENTOR(S) Hemant Thatte (Medfield, Massachusetts);  Kunda Biswas (Boston, Massachusetts);  Shukri Khuri (Westwood, Massachusetts);  Thomas Michel (Lincoln, Massachusetts)
ABSTRACT The present invention provides for compositions and methods for the preservation of tissues and organs ex vivo and in situ. In addition, the present invention provides for kits that may be used in the preparation of the solutions of the present invention. The present invention also provides a device for perfusing tissues and organs with the solutions of the present invention.
FILED Tuesday, April 10, 2001
APPL NO 10/257176
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07611920 Jost
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Steven R. Jost (Amherst, New Hampshire)
ABSTRACT A room temperature operation polycrystalline infrared responsive photodetector, manufactured by a process, comprising the steps of patterning vacuum-deposited material and dry-etching a photonic crystal structure with resonant coupling tuned to long wavelengths.
FILED Friday, November 17, 2006
APPL NO 11/601223
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/57
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07612038 Fallon et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Justin R. Fallon (Harvard, Massachusetts);  Beth McKechnie (Franklin, Massachusetts);  Michael Rafii (Baltimore, Maryland);  Hilliary Creely (Providence, Rhode Island);  Mark A. Bowe (Damascus, Maryland);  Alison Amenta (Pawtucket, Rhode Island);  Mary Lynn Mercado (Robbinsville, New Jersey);  Hiroki Hagiwara (Tokyo, Japan)
ABSTRACT The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.
FILED Wednesday, February 20, 2002
APPL NO 10/081736
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 03, 2009.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2009/fedinvent-patents-20091103.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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