FedInvent™ Patents
Patent Details for Tuesday, December 29, 2009
This page was updated on Monday, March 27, 2023 at 01:29 AM GMT
Department of Defense (DOD)
US 07636999 | Choi et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Molecular Imprints, Inc. (Austin, Texas) |
INVENTOR(S) | Byung-Jin Choi (Austin, Texas); Anshuman Cherala (Austin, Texas); Daniel A. Babbs (Austin, Texas) |
ABSTRACT | A method of retaining a substrate to a wafer chuck. The method features accelerating a portion of the substrate toward the wafer chuck, generating a velocity of travel of the substrate toward the wafer chuck, and reducing the velocity before the substrate reaches the wafer chuck. In this manner, the force of impact of the portion with the wafer chuck is greatly reduced, which is believed to reduce the probability that the structural integrity of the substrate, and layers on the substrate and/or the wafer chuck, are damaged. |
FILED | Monday, January 31, 2005 |
APPL NO | 11/047499 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/559 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07637224 | Portmann et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Helmut Portmann (Panama City Beach, Florida); Elan Moritz (Lynn Haven, Florida); David Everhart (Panama City, Florida); Ronald Swart (Panama City, Florida) |
ABSTRACT | An inflatable barrier system halts an approaching boat. A barrier support platform houses a pressurized gas source and a power supply and has a winch connected to a pair of cables. An inflatable barrier body member having a bow and stern is coupled to the pressurized gas source for inflation of the body member and the cables are connected to the bow and stern to deploy the inflated body member at the surface of the water and to maintain the bow above the surface and the stern below the surface of the water. A barrier controller provides signals indicative of the approaching boat to initiate the inflation of the inflatable barrier body member and the deployment of the inflated barrier body member at the surface with the bow above the surface and the stern below the surface without inflicting excessive damage to the boat or injury to its occupants. |
FILED | Friday, June 20, 2008 |
APPL NO | 12/214920 |
ART UNIT | 3617 — Printing/Measuring and Testing |
CURRENT CPC | Ships 114/345 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07637456 | Chavez et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Joey N. Chavez (Rio Rancho, New Mexico); Paul J. Cruz (Los Lunas, New Mexico) |
ABSTRACT | A manual starter for an engine includes a main housing, an output shaft, a spring housing, a spring, and an attachment unit. The output shaft is disposed at least partially inside the main housing, and is configured to supply a starting torque to the engine. The spring housing is disposed in the main housing. This spring is disposed in the spring housing, and is configured to receive an initial force from a starter cord and to supply the starting torque to the output shaft. The attachment unit is configured to selectively couple the spring to the output shaft before the engine has started and decouple the spring from the output shaft after the engine has started. |
FILED | Tuesday, June 19, 2007 |
APPL NO | 11/765169 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/53.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07637459 | Mast et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
INVENTOR(S) | James Grant Mast (Fort Worth, Texas); Charles Eric Covington (Colleyville, Texas); Paul Eugene Darden (Arlington, Texas); William L. McKeown (Euless, Texas) |
ABSTRACT | A weight-on-gear sensor for use on an aircraft with landing skids having a bracket and a displacement sensor attached to the bracket is disclosed. The bracket has a center member connecting a first end member to a second end member. The center member has a centerline and the end members extend from the centerline of the center member. Mounting members extend along the centerline of the center member to facilitate attachment of the bracket to a cross tube. The displacement sensor connects the first end member to the second end member. The displacement sensor is parallel to, and offset from, the centerline of the center member so that when a bending moment is applied to the center member the first displacement sensor is either elongated or shortened. |
FILED | Tuesday, August 10, 2004 |
APPL NO | 11/659748 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/108 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07637461 | Spanjers |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Gregory G. Spanjers (Albuquerque, New Mexico) |
ABSTRACT | A method whereby one or more conducting plates electrically-biased negatively with respect to a spacecraft's electrical potential and insulated from the spacecraft surface are located around the spacecraft surface whereby contaminant ions in a plasma surrounding the spacecraft are attracted to and accelerated through the conducting plates electric potential, caused to collide with the conductive surface, neutralized through collisions with surface atoms, and then reflected away from the spacecraft as neutral atoms or molecules. |
FILED | Wednesday, January 23, 2008 |
APPL NO | 12/018202 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/171.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638130 | Ching et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Wei-Mei Ching (Bethesda, Maryland); Daryl J. Kelly (Newark, Ohio); Gregory A. Dasch (Stone Mountain, Georgia) |
ABSTRACT | A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi for the Karp, Kato and Gilliam strains has been produced. The invention is useful for detecting prior exposure to scrub typhus, screening for and/or identification of at least one infectious strain-similarity (i.e. a Karp-like, Kato-like or Gilliam-like strain) based on its strength of reaction toward a truncated protein and as a component in vaccine formulation sand production of immune globulins for passive prophylaxis and immunity in subjects. |
FILED | Thursday, December 27, 2007 |
APPL NO | 11/964982 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638228 | Minteer et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
INVENTOR(S) | Shelley D. Minteer (Pacific, Missouri); Niki L. Akers (St. Louis, Missouri); Christine M. Moore (St. Louis, Missouri) |
ABSTRACT | Disclosed are bioanodes comprising a quaternary ammonium treated Nafion® polymer membrane and a dehydrogenase incorporated within the treated Nafion® polymer. The dehydrogenase catalyzes the oxidation of an organic fuel and reduces an adenine dinucleotide. The ion conducting polymer membrane lies juxtaposed to a polymethylene green redox polymer membrane, which serves to electro-oxidize the reduced adenine dinucleotide. The bioanode is used in a fuel cell to produce high power densities. |
FILED | Friday, July 11, 2003 |
APPL NO | 10/617452 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638300 | Schultz et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peter Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason W. Chin (Cambridge, United Kingdom); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (Lancaster, Pennsylvania); Miro Pastrnak (San Diego, California) |
ABSTRACT | The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids. |
FILED | Wednesday, October 18, 2006 |
APPL NO | 11/583551 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638333 | Lee et al. |
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ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | John S. Lee (Hagerstown, Maryland); Peter Pushko (Frederick, Maryland); Michael D. Parker (Frederick, Maryland); Jonathan F. Smith (Sabillasville, Maryland); Susan L. Welkos (Frederick, Maryland) |
ABSTRACT | Using the nontoxic PA protein from B. anthracis, a method and composition for use in inducing an immune response which is protective against anthrax in subjects is described. |
FILED | Wednesday, May 21, 2003 |
APPL NO | 10/442502 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/456 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638346 | Schowalter et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
INVENTOR(S) | Leo J. Schowalter (Latham, New York); Joseph A. Smart (Mooresville, North Carolina); Shiwen Liu (Acton, Massachusetts); Kenneth E. Morgan (Castleton, New York); Robert T. Bondokov (Watervliet, New York); Timothy J. Bettles (Bethlehem, Pennsylvania); Glen A. Slack (Scotia, New York) |
ABSTRACT | Semiconductor structures and devices based thereon include an aluminum nitride single-crystal substrate and at least one layer epitaxially grown thereover. The epitaxial layer may comprise at least one of AlN, GaN, InN, or any binary or tertiary alloy combination thereof, and have an average dislocation density within the semiconductor heterostructure is less than about 106 cm−2. |
FILED | Monday, August 14, 2006 |
APPL NO | 11/503660 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/47 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638353 | Beernink et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | United Solar Ovonic LLC (Auburn Hills, Michigan) |
INVENTOR(S) | Kevin Beernink (Clarkston, Michigan); Ginger Pietka (Harrison Township, Michigan); Timothy Barnard (Rochester Hills, Michigan) |
ABSTRACT | A method for making a semiconductor device having front-surface electrical terminals in which the device is manufactured so as to include a bottom electrode, a top electrode and a semiconductor body therebetween. A first bus bar is disposed in a groove in the semiconductor body. It is in electrical communication with the bottom electrode, and includes a tab portion which projects from the device. A second bus bar is in electrical communication with the top electrode, and is disposed atop the first electrode, and electrically insulated therefrom. The tab of the first bus bar provides one terminal of the device and is folded onto the second bus bar and is electrically insulated therefrom. The second bus bar provides the second terminal of the device. |
FILED | Tuesday, June 03, 2008 |
APPL NO | 12/131963 |
ART UNIT | 2823 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/57 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638379 | Cheng et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | SemiSouth Laboratories, Inc. (Starkville, Michigan); Mississippi State University (Mississippi State, Michigan) |
INVENTOR(S) | Lin Cheng (Starkville, Mississippi); Michael S. Mazzola (Starkville, Mississippi) |
ABSTRACT | Semiconductor devices and methods of making the devices are described. The devices can be implemented in SiC and can include epitaxially grown n-type drift and p-type trenched gate regions, and an n-type epitaxially regrown channel region on top of the trenched p-gate regions. A source region can be epitaxially regrown on top of the channel region or selectively implanted into the channel region. Ohmic contacts to the source, gate and drain regions can then be formed. The devices can include edge termination structures such as guard rings, junction termination extensions (JTE), or other suitable p-n blocking structures. The devices can be fabricated with different threshold voltages, and can be implemented for both depletion and enhanced modes of operation for the same channel doping. The devices can be used as discrete power transistors and in digital, analog, and monolithic microwave integrated circuits. |
FILED | Tuesday, November 06, 2007 |
APPL NO | 11/935442 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/193 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638498 | Escher et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Loma Linda University (Loma Linda, California) |
INVENTOR(S) | Alan P. Escher (Redlands, California); Fengchun Li (Loma Linda, California) |
ABSTRACT | A substance for preventing, delaying the onset of, or treating one or more than one autoimmune disease, the substance comprising a polynucleotide construct comprising a polynucleotide sequence encoding the pro-apoptotic protein BAX and encoding one or more than one autoantigen for the autoimmune disease. A method for preventing, delaying the onset of or treating an autoimmune disease in a patient comprising selecting a patient who is susceptible to developing the autoimmune disease, who is developing the autoimmune disease or who has the autoimmune disease and administering to the patient one or more than one dose of a polynucleotide construct comprising a polynucleotide sequence encoding the pro-apoptotic protein BAX and encoding one or more than one autoantigen for an autoimmune disease, or comprising a polynucleotide sequence encoding the adenoviral protein E3-GP19k, or comprising a polynucleotide sequence encoding ΔBCL-2. |
FILED | Thursday, August 09, 2007 |
APPL NO | 11/836661 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638554 | Waleh et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Nahid Waleh (Palo Alto, California); Nurulain T. Zaveri (Saratoga, California) |
ABSTRACT | Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) wherein R1 through R3 and R5 through R11 are defined herein, and α, β and γ are optional bonds, providing that when α is absent, β is present, and when β is absent, α is present. When α is present, preferred R4 moieties are selected from O, S, NH and CH2, and when α is absent, preferred R4 groups are selected from OH, SH, NH2 and CH3. When γ is present, the preferred R5 substituent is O, while when γ is absent, the preferred R5 substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use. |
FILED | Friday, April 14, 2006 |
APPL NO | 11/404230 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638751 | Dauler et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Eric A. Dauler (Charlestown, Massachusetts); Andrew J. Kerman (Somerville, Massachusetts); Karl K. Berggren (Arlington, Massachusetts); Vikas Anant (Somerville, Massachusetts); Joel K. W. Yang (Cambridge, Massachusetts) |
ABSTRACT | A multi-element optical detector includes a plurality of optical detector elements capable of producing an output signal having information about the state of an incident electromagnetic radiation as a function of time. An active region includes a photosensitive region of one of the optical detector elements separated in part or in whole from the photosensitive region of at least one other optical detector element by a distance less than the wavelength of the electromagnetic radiation that the optical detector elements are being used to detect. |
FILED | Friday, May 09, 2008 |
APPL NO | 12/118187 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Radiant energy 250/214.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638768 | Otten, III et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Kestrel Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Leonard John Otten, III (Placitas, New Mexico); Paul Harrison (Albuquerque, New Mexico); Desirae L. Cuevas (Albuquerque, New Mexico); Paul Fournier (Albuquerque, New Mexico) |
ABSTRACT | The device and method of the present invention are useful for determining the characteristics of an infrared wavefront. The present invention involves positioning a beam of light containing the infrared wavefront to be characterized onto a distorted grating, using the grating to produce a plurality of images, determining the infrared wavefront from the plurality of images and analyzing the infrared wavefront for features that characterize the infrared wavefront. |
FILED | Tuesday, June 19, 2007 |
APPL NO | 11/820651 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/338.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638791 | Razeghi |
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APPLICANT(S) | |
ASSIGNEE(S) | MP Technologies, LLC (Evanston, Illinois) |
INVENTOR(S) | Manijeh Razeghi (Wilmette, Illinois) |
ABSTRACT | An improved photodiode and method of producing an improved photodiode comprising doping an InAs layer of an InAs/GaSb region situated on top of an InAs/GaSb:Be superlattice and below an InAs:Si/GaSb regions such that the quantum efficiency of the photodiode increases and dominant dark current mechanisms change from diffusion to band-to-band tunneling as the InAs layer is doped with Beryllium. |
FILED | Wednesday, March 05, 2008 |
APPL NO | 12/042804 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638818 | Wu et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Cree, Inc. (Goleta, California) |
INVENTOR(S) | Yifeng Wu (Goleta, California); Marcia Moore (Santa Barbara, California); Tim Wisleder (Auckland, New Zealand); Primit Parikh (Goleta, California) |
ABSTRACT | A semiconductor device, and particularly a high electron mobility transistor (HEMT), having a plurality of epitaxial layers and experiencing an operating (E) field. A negative ion region in the epitaxial layers to counter the operating (E) field. One method for fabricating a semiconductor device comprises providing a substrate and growing epitaxial layers on the substrate. Negative ions are introduced into the epitaxial layers to form a negative ion region to counter operating electric (E) fields in the semiconductor device. Contacts can be deposited on the epitaxial layers, either before or after formation of the negative ion region. |
FILED | Friday, July 07, 2006 |
APPL NO | 11/482330 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/192 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638937 | Eden et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of the University Illinois (Urbana, Illinois) |
INVENTOR(S) | J. Gary Eden (Mahomet, Illinois); Sung-Jin Park (Yong-In, South Korea); Clark J. Wagner (Urbana, Illinois) |
ABSTRACT | Roll to roll fabrication methods of the invention enable low cost mass production of microdischarge devices and arrays. A preferred embodiment method of fabricating a discharge device includes providing a dielectric layer sheet, a first electrode, and a second electrode sheet. A cavity is provided through at least a portion of the dielectric layer sheet. At least the dielectric layer sheet and second electrode sheet are rolled together. Another preferred embodiment method of fabrication a discharge device includes method of fabricating a discharge device includes providing a dielectric layer sheet and a cavity through at least a portion of the dielectric layer sheet. A first electrode is disposed as a film of conducting material on the dielectric layer sheet around a rim of the cavity. A second electrode sheet is provided. The dielectric layer sheet is rolled together with first electrode and second electrode sheets. |
FILED | Tuesday, March 01, 2005 |
APPL NO | 11/070100 |
ART UNIT | 2821 — Semiconductors/Memory |
CURRENT CPC | Electric lamp and discharge devices 313/503 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639093 | Ardehali |
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APPLICANT(S) | |
ASSIGNEE(S) | Tialinx, Inc. (Newport Beach, California) |
INVENTOR(S) | Mohammad Ardehali (Camarillo, California) |
ABSTRACT | In one embodiment, a voltage-controlled oscillator is provided having an output signal whose frequency is responsive to a tuning signal and is independent of amplitude of oscillation. The voltage-controlled oscillator includes: a plurality of differential inverter stages coupled to form a loop, each differential inverter stage having a differential pair of transistors configured to steer a tail current from a current source, the current source sourcing the tail current responsive to a feedback signal; and a control circuit configured to generate the feedback signal responsive to a reference signal such that an amplitude of the output signal is independent of the tuning signal and depends on the reference signal, and the frequency of oscillation is decoupled from the amplitude of oscillation. |
FILED | Saturday, December 30, 2006 |
APPL NO | 11/618812 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Oscillators 331/57 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639105 | Ayazi et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Farrokh Ayazi (Atlanta, Georgia); Gavin Kar-Fal Ho (Cambridge, Massachusetts); Reza Abdolvand (Stillwater, Oklahoma) |
ABSTRACT | Disclosed are micromechanical resonator apparatus having features that permit multiple resonators on the same substrate to operate at different operating frequencies. Exemplary micromechanical resonator apparatus includes a support substrate and suspended micromechanical resonator apparatus having a resonance frequency. In one embodiment, the suspended micromechanical resonator apparatus comprises a device substrate that is suspended from and attached to the support substrate, a piezoelectric layer formed on the suspended device substrate, and a plurality of interdigitated upper electrodes formed on the piezoelectric layer. In another embodiment, the suspended micromechanical resonator apparatus comprises a device substrate that is suspended from and attached to the support substrate, a lower electrode formed on the suspended device substrate, a piezoelectric layer formed on the lower electrode, and a plurality of interdigitated upper electrodes formed on the piezoelectric layer. The substrate may comprise a silicon substrate, or a semiconductor-on-insulator substrate, such as a diamond on silicon substrate. Additionally, lateral frequency-adjusting electrodes may be disposed adjacent to the resonator apparatus that are separated therefrom by a capacitive gap, and which are configured to receive a direct current voltage that adjusts the resonance frequency of the resonator apparatus. |
FILED | Friday, January 18, 2008 |
APPL NO | 12/009527 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Wave transmission lines and networks 333/186 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639201 | Marklein et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Eric Marklein (Amherst, Massachusetts); Daniel Schaubert (Amherst, Massachusetts) |
ABSTRACT | An ultra wideband loop antenna having a planar antenna element defining an at least semi-elliptical perimeter having a major axis, a minor axis and a center. There is also an elongated, contiguous discontinuity in the antenna element that is symmetric about the antenna element minor axis, entirely located within the antenna element, and defining a discontinuity feed end located on the minor axis and spaced from one side of the antenna element perimeter by an element feed width, and further defining an opposed discontinuity ground end located on the minor axis and spaced from the opposing side of the antenna element perimeter by an element ground width, to define an antenna element ground portion, wherein the feed width is greater than the ground width. The antenna also has a feed region connecting the feed end of the discontinuity to the perimeter, to define antenna element feed ends that are adjacent to the feed region. |
FILED | Thursday, January 17, 2008 |
APPL NO | 12/015701 |
ART UNIT | 2821 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Radio wave antennas 343/866 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639356 | Prokes et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Sharka M. Prokes (Columbia, Maryland); Orest J. Glembocki (Alexandria, Virginia) |
ABSTRACT | An apparatus comprising a substrate and at least two nanowires on the substrate, the nanowires comprising a core and a metal shell, wherein the core is selected from the group consisting of a semiconductor and a dielectric, thereby forming a nanowire-composite to allow plasmon coupling for enhancements of the electric fields and enhancements of the surface enhanced Raman signal (SERS) and enhancements of the chemical or biological specificity and sensitivity. A method of making a SERS-active substrate comprising providing a substrate and affixing a plurality of nanowires on the substrate thereby forming a nano-composite, creating plasmon coupling leading to enhanced electric fields in the vicinity of the nanowires and enhancements of the surface enhanced Raman signal (SERS) and enhancements of the chemical or biological specificity and sensitivity. |
FILED | Tuesday, April 08, 2008 |
APPL NO | 12/078888 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/301 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639462 | Graebel et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Jeffrey Graebel (Plymouth, Minnesota); Yifei Zhang (Blaine, Minnesota) |
ABSTRACT | A method and system for reducing transient event effects, such as radiation effects, in an electrostatic discharge (ESD) power clamp is provided. The ESD power clamp includes triggering circuitry to determine the on-time of the power clamp during an ESD event, and drive circuits driving pull down devices to carry the ESD current. Two separate driver circuits are used to control the pull down circuits separately to guard against a single event effect (SEE). The ESD power clamp operates when both drive circuits are operated simultaneously to shunt the ESD to ground. |
FILED | Tuesday, October 25, 2005 |
APPL NO | 11/257510 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/56 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639565 | Bernecky et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | W. Robert Bernecky (Mystic, Connecticut); Matthew J. Krzych (Tiverton, Rhode Island) |
ABSTRACT | A matched-field based sonar system and method of use that supports real-time, three-dimensional acoustic source localization using a mobile, horizontal array. The system receives and processes acoustic array, non-acoustic array, and own-ship navigational data in the matched-field process (MFP). Driven by own-ship and array status, a global bathymetry database and an acoustic environmental model are used to generate replicas for the MFP. If a three-dimensional tracker is assigned, then the tracker will steer the search region to maintain contact on the target of interest. Displays are provided to the user including tracker displays (which provide tracker information), MFP ambiguity surface displays (which support contact localization), and non-acoustic and navigational displays. A control interface allows a user to control the search region in bearing, range, depth, and frequency; assign the three-dimensional tracker function; and control display processing. |
FILED | Monday, June 25, 2007 |
APPL NO | 11/767787 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/131 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639628 | Kogge |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Notre Dame du lac (Notre Dame, Indiana) |
INVENTOR(S) | Peter M. Kogge (Granger, Indiana) |
ABSTRACT | A method that includes activating and deactivating two counts between an active state and not an active state such that no more than one count at a time is in an active state. The method also includes receiving a request packet of information that requires a reply and incrementing the count that is in an active state, and setting a flag in the request packet of information that requires a reply, the flag being set to correspond to the count that is in the active state. The method further includes receiving a reply packet of information corresponding to a previously received request packet of information, the reply packet of information having a flag setting corresponding to the previously received request packet of information, and decrementing the count that corresponds to the flag setting of the reply packet of information. A network is also disclosed. |
FILED | Friday, July 14, 2006 |
APPL NO | 11/457543 |
ART UNIT | 2416 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/252 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639663 | Nerses et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | ITT Manufacturing Enterprises, Inc. (Wilmington, Delaware) |
INVENTOR(S) | Annita Nerses (Arlington, Virginia); Robert M. Wetstein (Nanuet, New York); Kaushik B. Patel (Bridgewater, New Jersey); Jon Schafer (Princeton Junction, New Jersey) |
ABSTRACT | The present invention protocol offers guaranteed Quality of Service (QoS) for a predetermined number of circuits in a highly dynamic, scalable network. The present invention protocol employs a Time Division Multiple Access (TDMA) reservation scheme to transmit deterministic data (e.g., image data) to a destination, while utilizing a Carrier Sense Multiple Access/Collision Avoidance (CSMA/CA) contention scheme to support non-deterministic data traffic. The protocol operates over a link-state based routing protocol that reliably floods routing and resource reservation information to the nodes in the network. Moreover, the present invention capitalizes on certain properties of a radio, such as a RAKE type receiver, to enable simultaneous re-transmissions of resource and route reservation information to constructively interfere and enhance the strength and range of the signal. |
FILED | Friday, March 04, 2005 |
APPL NO | 11/071587 |
ART UNIT | 2617 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/347 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639714 | Stolfo et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Ke Wang (Mountain View, California) |
ABSTRACT | A method, apparatus and medium are provided for detecting anomalous payloads transmitted through a network. The system receives payloads within the network and determines a length for data contained in each payload. A statistical distribution is generated for data contained in each payload received within the network, and compared to a selected model distribution representative of normal payloads transmitted through the network. The model payload can be selected such that it has a predetermined length range that encompasses the length for data contained in the received payload. Anomalous payloads are then identified based on differences detected between the statistical distribution of received payloads and the model distribution. The system can also provide for automatic training and incremental updating of models. |
FILED | Friday, November 12, 2004 |
APPL NO | 10/986447 |
ART UNIT | 2416 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/474 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639722 | Paxton et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Alan H. Paxton (Albuquerque, New Mexico); Harold C. Miller (Albuquerque, New Mexico); Jonathan Stohs (Albuquerque, New Mexico) |
ABSTRACT | An optical element for homogenizing and, possibly, concentrating the output from high-power two-dimensional semiconductor laser arrays, which has the basic shape of a convex-flat cylindrical lens with a facet cut into the convex surface for each individual semiconductor laser bar. |
FILED | Monday, October 29, 2007 |
APPL NO | 11/926246 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/71 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639868 | Regli et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | William C. Regli (Philadelphia, Pennsylvania); Cheuk Yiu Ip (Hong Kong, China Hong Kong); Leonard Sieger (Philadelphia, Pennsylvania) |
ABSTRACT | A method of providing an automated classifier for 3D CAD models wherein the method provides an algorithm for learning new classifications. The method enables existing model comparison algorithms to adapt to different classifications that are relevant in many engineering applications. This ability to adapt to different classifications allows greater flexibility in data searching and data mining of engineering data. |
FILED | Wednesday, June 16, 2004 |
APPL NO | 10/869061 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/159 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07640283 | Hou |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | Hsieh S. Hou (Rancho Palos Verdes, California) |
ABSTRACT | A front-end shared Haar transform is particularly adapted for cascade connection to an appended transform for providing lossless transform of an input data set, the appended transforms selected from the group consisting of an appended discrete cosine type-II (DCT-II) transform for forming a lossless DCT-II transform, an appended discrete cosine type-IV (DCT-IV) transform for forming a lossless DCT-IV transform, and an appended Haar transform for forming a lossless extended Haar transform. |
FILED | Monday, June 27, 2005 |
APPL NO | 11/168979 |
ART UNIT | 2193 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07640386 | Coteus et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Paul W. Coteus (Yorktown Heights, New York); Warren E. Maule (Cedar Park, Texas); Edward J. Seminaro (Milton, New York); Robert B. Tremaine (Stormville, New York) |
ABSTRACT | Systems and methods for providing memory modules with multiple hub devices. Exemplary systems include a cascade-interconnect memory system with a memory bus, a memory controller and a memory module. The memory controller is in communication with the memory bus for generating, receiving and responding to memory access requests. The memory module includes a first hub device with three or more ports and a second hub device with three or more ports. A first port on the first hub device is in communication with the memory controller via the memory bus, a second port on the first hub device is in communication with a first set of memory devices, and a third port on the first hub device is cascade connected to a first port on the second hub device. A second port on the second hub device is in communication with a second set of memory devices and a third port on the second hub device supports a cascaded connection to a subsequent hub device in the memory system. |
FILED | Wednesday, May 24, 2006 |
APPL NO | 11/420046 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electrical computers and digital data processing systems: Input/output 710/316 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07640511 | Keel et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Paul Erich Keel (Cambridge, Massachusetts); Jeffrey Huang (Concord, Massachusetts) |
ABSTRACT | A system identifies information based on relations between information objects. The system identifies a first set of information objects that each includes associated positional information. The system identifies at least one spatial relation between the first set of information objects based on a spatial arrangement of the information objects as determined by positional information associated with the first set of information objects. The system further identifies a second set of information objects based on the relation(s) between the first set of information objects and outputs an identity of the second set of information objects. A unique card layout is also disclosed. |
FILED | Friday, April 29, 2005 |
APPL NO | 11/118301 |
ART UNIT | 2173 — Graphical User Interface and Document Processing |
CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/769 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07640539 | Alexander, III et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | William Preston Alexander, III (Austin, Texas); Scott Thomas Jones (Austin, Texas); Frank Eliot Levine (Austin, Texas); Robert John Urquhart (Austin, Texas) |
ABSTRACT | A system and method for collecting a plurality of metrics during a single run of a computer program. The mechanism of the present invention initializes a plurality of counters to count events associated with metrics of interest. The mechanism of the present invention then counts the occurrence of events associated with metrics of interest during a single execution of a computer program. Responsive to a determination that a counter in a plurality of counters has generated an interrupt, the interrupt is rerouted to an interrupt handler, wherein the interrupt handler generates trace records comprising trace information corresponding to the interrupt. The mechanism of the present invention then generates profiles for the trace records, wherein the profiles differentiate the trace records based on the metric type associated with each trace record. |
FILED | Tuesday, April 12, 2005 |
APPL NO | 11/104257 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE41063 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Gee-Kung Chang (Smyrna, Georgia); Arshad Chowdhury (Atlanta, Georgia); Georgios Ellinas (Nicosia, Cyprus) |
ABSTRACT | An optical signaling header technique applicable to optical networks wherein packet routing information is embedded in the same channel or wavelength as the data payload so that both the header and data payload propagate through network elements with the same path and the associated delays. The technique effects survivability and security of the optical networks by encompassing conventional electronic security with an optical security layer by generating replicated versions of the input data payload at the input node, and the transmission of each of the replicated versions over a corresponding one of the plurality of links. Moreover, each of the links is composed of multiple wavelengths to propagate optical signals or optical packets, and each of the replicated versions of the data payload may be propagated over a selected one of the wavelengths in each corresponding one of the plurality of links. |
FILED | Friday, May 02, 2008 |
APPL NO | 12/114622 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Optical communications 398/51 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 07638032 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Dao Min Zhou (Saugus, California); Amy Hines (Monterey Park, California); James Singleton Little (Saugus, California); Robert J. Greenberg (Los Angeles, California) |
ABSTRACT | The present invention relates to a process for cathodic protection of electrode or electrode materials wherein negative bias is applied on the electrode. the negative bias is obtained by asymmetric current pulse. The asymmetric current pulse is obtained by performing negative phase with higher amplitude. The asymmetric current pulse is obtained by performing negative phase with wider pulse width than that of the anodic phase. The asymmetric current pulse is obtained by performing negative phase with higher amplitude and with wider pulse width than that of the anodic phase. The present invention further relates to a process for cathodic protection of electrode or electrode materials, wherein negative bias is applied on the electrode, wherein the negative bias is obtained by asymmetric current pulse, wherein the asymmetric current pulse is obtained by performing negative phase with wider pulse width than that of the anodic phase. The wider pulse width is obtained by pulse trains. |
FILED | Thursday, October 25, 2007 |
APPL NO | 11/924349 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/740 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638119 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Jeffrey A. Johnson (Blanchardville, Wisconsin); Marcus J. Calkins (Madison, Wisconsin) |
ABSTRACT | A method of diminishing the symptoms of neurodegenerative disease in a patient is disclosed. In one embodiment, the method comprises the steps of: (a) identifying a patient with a neurodegenerative disease, (b) producing a cell culture, wherein the cell culture comprises cells with induced antioxidant response element (ARE) mediated transcription, and (c) transplanting at least a portion of the cell culture into the brain of the patient, wherein symptoms of neurodegenerative disease are diminished. |
FILED | Wednesday, November 30, 2005 |
APPL NO | 11/290293 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638122 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida); Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Hua Yu (Tampa, Florida); Drew Pardoll (Brookeville, Maryland); Richard Jove (Tampa, Florida) |
ABSTRACT | The present invention relates to methods for treating and/or preventing cancer. In particular the present invention relates to ex vivo immunotherapeutic methods. The methods comprise decreasing Stat3 (signal transducer and activator of transcription3) expression and/or function in tumor cells and the administration of such cells to a subject in need of treatment and/or prevention. Other methods of the invention comprise activating T-cells by co-culturing the T-cells with the tumor cells with decreased Stat3 expression or function. The invention further encompasses methods comprising decreasing Stat3 expression or function in antigen-presenting cells and co-administering tumor cells and the antigen-presenting cells with decreased Stat3 function to a patient. The invention further relates to methods for stimulating dendritic cell differentiation. |
FILED | Friday, March 07, 2003 |
APPL NO | 10/383707 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.710 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638128 | Dzau et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Duke University (Durham, North Carolina) |
INVENTOR(S) | Victor Dzau (Durham, North Carolina); Maria Mirotsou (Dresden, Germany) |
ABSTRACT | A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury associated with ischemic conditions. |
FILED | Monday, August 21, 2006 |
APPL NO | 11/508010 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638134 | Panicali et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Dennis L. Panicali (Acton, Massachusetts); Gail P. Mazzara (Winchester, Massachusetts); Linda R. Gritz (Somerville, Massachusetts); Patricia Greenhalgh (Bedford, Massachusetts) |
ABSTRACT | The present invention provides novel insertion sites for introducing DNA into pox vectors. |
FILED | Friday, February 20, 2004 |
APPL NO | 10/543944 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/232.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638135 | Rich et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Rebecca L. Rich (Salt Lake City, Utah); Bernd Kriekemeyer (Ulm, Germany); Rick T. Owens (Stewartsville, New Jersey); Magnus Hook (Houston, Texas); Barbara E. Murray (Houston, Texas); Sreedhar R. Nallapareddy (Houston, Texas); George M. Weinstock (Houston, Texas) |
ABSTRACT | A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized to inhibit adhesion of enterococcal bacteria to extracellular matrix proteins. The N-terminal region of Ace contained a region (residues 174-319), or A domain, contains several 47-residue tandem repeat units between the collagen-binding site and cell wall-associated regions. The Ace protein can be utilized in methods of preventing and/or treating enterococcal infection, and in addition, antibodies raised against Ace, or its A domain, can be used to effectively inhibit the adhesion of enterococcal cells to a collagen substrate. |
FILED | Monday, April 11, 2005 |
APPL NO | 11/102757 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/234.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638269 | Lingappa et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (, California); The University of Washington (, Washington) |
INVENTOR(S) | Jaisri R. Lingappa (Seattle, Washington); Kevin C. Klein (Seattle, Washington); Vishwanath R. Lingappa (San Francisco, California) |
ABSTRACT | A cell-free method for translation and assembly of viral capsid and capsid intermediates is disclosed. Also disclosed are novel capsid assembly intermediates and novel host proteins which bind to such assembly intermediates. The invention also includes a screening method for compounds that alter viral capsid assembly, and a method of treating viral infection using compounds which inhibit the capsid assembly pathway. |
FILED | Friday, September 13, 2002 |
APPL NO | 10/243509 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638273 | Hahnfeldt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Caritas St. Elizabeth's Medical Center of Boston, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Philip Hahnfeldt (Wellesley, Massachusetts); Lynn Hlatky (Wellesley, Massachusetts) |
ABSTRACT | Tumors can be directed into a vasculogenic program and used to regenerate tissues in a verterbrate host, identify factors originating from the tumor that are useful for tissue regeneration, and to generate such factors for use in a subject apart from the tumor itself. |
FILED | Wednesday, October 18, 2006 |
APPL NO | 11/582872 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638278 | Pollack et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Jonathan Robert Pollack (Burlingame, California); Jacques Lapointe (Montréal, Canada); James Duane Brooks (Stanford, California) |
ABSTRACT | The invention describes DNA copy number alterations (CNAs), identifiable by technologies such as array-based comparative genomic hybridization (array CGH) or fluorescence in situ hybridization (FISH), that define distinct genetic subtypes of prostate cancer, and are useful for improved prognostication and treatment stratification for patients with prostate cancer. |
FILED | Friday, May 12, 2006 |
APPL NO | 11/433844 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638284 | Estes et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); Board of Regents of the University of Texas (Austin, Texas) |
INVENTOR(S) | D. Mark Estes (League City, Texas); Amy Umbright (St. Louis, Missouri); Karen Haas (Durham, North Carolina) |
ABSTRACT | The invention provides an isolated and purified nucleic acid molecule encoding mammalian immunoglobulin A inducing protein (IGIP), and methods of using the IGIP nucleic acid molecule and IGIP, e.g., to prepare antibodies. Also provided is an anti-IGIP antibody and uses therefor. |
FILED | Tuesday, July 26, 2005 |
APPL NO | 11/189559 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638300 | Schultz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peter Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason W. Chin (Cambridge, United Kingdom); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (Lancaster, Pennsylvania); Miro Pastrnak (San Diego, California) |
ABSTRACT | The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids. |
FILED | Wednesday, October 18, 2006 |
APPL NO | 11/583551 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638302 | Maihle et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Tumor Biology Investment Group, Inc. (Lexington, Kentucky) |
INVENTOR(S) | Nita J. Maihle (Rochester, Minnesota); Hakjoo Lee (Rochester, Minnesota) |
ABSTRACT | The present invention discloses a method using human soluble ErbB3, for example p85-sErbB3, as a negative regulator of heregulin-stimulated ErbB2, ErbB3, and ErbB4 activation. The present invention also discloses p85-sErbB3 binding to heregulin with an affinity comparable to that of full-length ErbB3, and competitively inhibiting high affinity heregulin binding to ErbB2/ErbB3 heterodimers on the cell surface of breast carcinoma cells. The present invention also uses p85-sErbB3 to inhibit heregulin-induced phosphorylation of ErbB2, ErbB3, and ErbB4 in cells, as a negative regulator of heregulin-stimulated signal transduction, and as a block for cell growth. The present invention is also directed to nucleic acids and expression vectors encoding p85-sErbB3, host cells harboring such expression vectors, and methods of producing the protein. The present invention discloses a method of therapeutically treating human malignancies associated with heregulin-mediated cell growth such as breast and prostate cancer. |
FILED | Wednesday, January 23, 2008 |
APPL NO | 12/018515 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638303 | Maihle et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Tumor Biology Investment Group, Inc. (Lexington, Kentucky) |
INVENTOR(S) | Nita J. Maihle (New Haven, Connecticut); Hakjoo Lee (Pittsford, New York) |
ABSTRACT | The present invention discloses a method using human soluble ErbB3, for example p85-sErbB3, as a negative regulator of heregulin-stimulated ErbB2, ErbB3, and ErbB4 activation. The present invention also discloses p85-sErbB3 binding to heregulin with an affinity comparable to that of full-length ErbB3, and competitively inhibiting high affinity heregulin binding to ErbB2/ErbB3 heterodimers on the cell surface of breast carcinoma cells. The present invention also uses p85-sErbB3 to inhibit heregulin-induced phosphorylation of ErbB2, ErbB3, and ErbB4 in cells, as a negative regulator of heregulin-stimulated signal transduction, and as a block for cell growth. The present invention is also directed to nucleic acids and expression vectors encoding p85-sErbB3, host cells harboring such expression vectors, and methods of producing the protein. The present invention discloses a method of therapeutically treating human malignancies associated with heregulin-mediated cell growth such as breast and prostate cancer. |
FILED | Monday, June 23, 2008 |
APPL NO | 12/144166 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638319 | Cardozo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Timothy Cardozo (New York, New York); Susan Zolla-Pazner (New York, New York) |
ABSTRACT | Newly discovered structural characteristic of the gp120 V3 loop have resulted in a “rule” or algorithm, that is used in a method for determining whether a subject is infected with HIV-1 virus that expresses selectivity for CXCR4 or CCR5 chemokine receptors. A positively charged surface patch defined by V3 loop residues 11 and 24 or 25 at the base of the β-strands in the V3 loop and the homologous β2-β3 chemokine hairpin is responsible for CXCR4 receptor selection. Thus a method for detecting the presence of HIV-1 virus that is selective for X4-co-receptors in a subject infected with HIV-1 or suspected of being infected, from the amino acid sequence of at least a part of the HIV-1 gp120 V3 region peptide that includes residues 11, 24 and 25, or from the nucleotide sequence of a nucleic acid encoding said V3 region peptide, is disclosed. |
FILED | Tuesday, March 07, 2006 |
APPL NO | 11/369010 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638322 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Minhyung Lee (Salt Lake City, Utah); Sung Wan Kim (Salt Lake City, Utah) |
ABSTRACT | Plasmids useful for treating ischemic disease, such as ischemic heart disease, are described. The plasmids express vascular endothelial growth factor (VEGF) under the control of a promoter (RTP801) that is up-regulated under hypoxic conditions. Pharmaceutical compositions for treating ischemic disease include mixtures of the hypoxia-regulated VEGF plasmids and pharmaceutically acceptable carriers. Methods for treating ischemic disease include administering such pharmaceutical compositions to a person in need of such treatment. |
FILED | Monday, February 23, 2004 |
APPL NO | 10/546115 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638324 | Reed et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Burnham Institute for Medical Research (La Jolla, California) |
INVENTOR(S) | John C. Reed (Rancho Santa Fe, California); Adam Godzik (San Diego, California); Bin Guo (San Diego, California) |
ABSTRACT | The invention provides Bcl-G polypeptides and encoding nucleic acids. Bcl-G polypeptides include Bcl-GL and Bcl-GS. The invention also provides mouse Bcl-G. The invention also provides vectors containing Bcl-G nucleic acids, host cells containing such vectors, Bcl-G anti-sense nucleic acids and related compositions. The invention additionally provides Bcl-G oligonucleotides that can be used to hybridize to or amplify a Bcl-G nucleic acid. Anti-Bcl-G specific antibodies are also provided. Further provided are kits containing Bcl-G nucleic acids or Bcl-G specific antibodies. Such kits and reagents can be used to diagnose cancer, monitor response to therapy, or predict the prognosis of a cancer patient. The invention additionally provides methods of modulating apoptosis using Bcl-G polypeptides, encoding nucleic acids, or compounds that modulate the activity or expression of Bcl-G polypeptides. The methods for modulating apoptosis can be used to treat diseases such as cancer. |
FILED | Thursday, December 14, 2000 |
APPL NO | 09/738396 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638331 | Godbey et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Administration of the Tulane Rducation Fund (New Orleans, Louisiana) |
INVENTOR(S) | W. Terrance Godbey (New Orleans, Louisiana); Anthony Atala (Winston-Salem, North Carolina) |
ABSTRACT | The present invention provides methods and constructs for selectively expressing an Apoptosis-Inducing Gene (AIG) in a population of cells that overexpress cyclooxygenase-2 (COX-2) to induce apoptosis in the cell. To achieve this goal a chimeric gene construct is used that comprises a cyclooxygenase-2 promoter (COX-2 promoter) that is operably linked to at least one AIG such that the COX-2 promoter is activated in cells that overexpress COX-2, thereby resulting in transcription and translation of the AIG, which in turn activates apoptosis in the cell. Thus, apoptosis is selectively induced in only those cells capable of overexpressing COX-2. |
FILED | Thursday, December 23, 2004 |
APPL NO | 11/023020 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/440 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638341 | Rubinsky et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Berkeley, California) |
INVENTOR(S) | Boris Rubinsky (Albany, California); Cesar A. Gonzalez (Anahuac, Mexico) |
ABSTRACT | A method of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample. An apparatus for determining the condition of a bulk tissue sample, having: a first induction coil (or antenna); a second induction coil (or antenna); an alternating current power supply connected to the first induction coil (or antenna), the alternating current power supply configured to generate a spectrum of currents (or voltage) in the first induction coil (or antenna); and a measurement system connected to the second induction coil (or antenna), wherein the measurement system is configured to measure a phase shift difference in the spectrum of currents (or voltages) between the first and second induction coils (or antennae) when the first and second induction coils (or antennae) are positioned on opposite sides of a tissue sample. |
FILED | Friday, May 12, 2006 |
APPL NO | 11/664755 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/149 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638492 | Wood et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Genetics Institute, LLC (Cambridge, Massachusetts) |
INVENTOR(S) | Clive R. Wood (Boston, Massachusetts); Gordon J. Freeman (Brookline, Massachusetts) |
ABSTRACT | The invention identifies PD-1 as a receptor for B7-4. B7-4 can inhibit immune cell activation upon binding to an inhibitory receptor on an immune cell. Accordingly, the invention provides agents for modulating PD-1, B7-4, and the interaction between B7-4 and PD-1 in order to modulate a costimulatory or an inhibitory signal in a immune cell resulting in modulation of the immune response. |
FILED | Thursday, August 31, 2006 |
APPL NO | 11/514328 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638494 | Fogelman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alan M. Fogelman (Beverly Hills, California); Mohamad Navab (Los Angeles, California) |
ABSTRACT | This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The peptides are highly stable and readily administered via an oral route. |
FILED | Tuesday, April 01, 2003 |
APPL NO | 10/520207 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638528 | Kucera et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Wake Forest University School of Medicine (Winston-Salem, North Carolina); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Louis S. Kucera (Pfafftown, North Carolina); Ronald A. Fleming (Cary, North Carolina); Khalid S. Ishaq (Chapel Hill, North Carolina); Gregory L. Kucera (Winston-Salem, North Carolina); Susan L. Morris-Natschke (Apex, North Carolina) |
ABSTRACT | The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions of the invention include compounds which comprise a phosphocholine moiety covalently conjugated with one or more antiviral agents (e.g. nucleoside analogue, protease inhibitor, etc.) to a lipid backbone. The invention also includes pharmaceutical compositions and kits for use in treatment of a virus infection in mammals. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to treat the infection, to a mammal infected with a virus. Additionally, the invention includes compositions and methods useful for combating a cancer in a mammal and for facilitating delivery of a therapeutic agent to a mammalian cell. The compositions of the invention include compounds which comprise an alkyl lipid or phospholipid moiety covalently conjugated with an anticancer agent (e.g. a nucleoside analogue). The invention also includes pharmaceutical compositions and kits for combating a cancer and for facilitating delivery of a therapeutic agent to a mammalian cell. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to combat a cancer or to facilitate delivery of a therapeutic agent to a mammalian cell. |
FILED | Thursday, April 06, 2006 |
APPL NO | 11/398529 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/283 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638543 | Verkman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alan Verkman (San Francisco, California); Tonghui Ma (San Francisco, California) |
ABSTRACT | The invention provides compositions, pharmaceutical preparations and methods for inhibition of cystic fibrosis transmembrane conductance regulator protein (CFTR) that are useful for the study and treatment of CFTR-mediated diseases and conditions. The compositions and pharmaceutical preparations of the invention may comprise one or more thiazolidinone compounds, and may additionally comprise one or more pharmaceutically acceptable carriers, excipients and/or adjuvants. The methods of the invention comprise, in certain embodiments, administering to a patient suffering from a CFTR-mediated disease or condition, an efficacious amount of a thiazolidinone compound. In other embodiments the invention provides methods of inhibiting CFTR that comprise contacting cells in a subject with an effective amount of a thiazolidinone compound. In addition, the invention features a non-human animal model of CFTR-mediated disease which model is produced by administration of a thiazolidinone compound to a non-human animal in an amount sufficient to inhibit CFTR. |
FILED | Monday, June 11, 2007 |
APPL NO | 11/761295 |
ART UNIT | 1614 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/369 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638544 | Harran et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Patrick G. Harran (Dallas, Texas); Xiaodong Wang (Dallas, Texas); Jef K. De Brabander (Dallas, Texas); Lin Li (Dallas, Texas); Ranny Mathew Thomas (Dallas, Texas); Hidetaka Suzuki (Dallas, Texas) |
ABSTRACT | Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of the dimeric mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology. |
FILED | Monday, December 17, 2007 |
APPL NO | 11/958365 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/374 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638624 | Glick |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Gary D. Glick (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like. |
FILED | Tuesday, January 03, 2006 |
APPL NO | 11/324419 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Organic compounds 540/217 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638637 | Lynch et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Kevin R. Lynch (Charlottesville, Virginia); Timothy L. Macdonald (Charlottesville, Virginia) |
ABSTRACT | The present invention relates to S1P analogs that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds have the general structure (I) wherein R11 is C5-C18 alkyl or C5-C18 alkenyl; Q is selected from the group consisting of C3-C6 optionally substituted cycloalkyl, C3-C6 optionally substituted heterocyclic, C3-C6 optionally substituted aryl C3-C6 optionally substituted heteroaryl and; R2 is selected from the group consisting of H, C1-C4 alkyl, (C1-C4 alkyl)OH and (C1-C4 alkyl)NH2; R23 is H or C1-C4 alkyl, and R15 is a phosphonate ester or a phosphate ester or a pharmaceutically acceptable salt or tautomer thereof. |
FILED | Wednesday, November 03, 2004 |
APPL NO | 10/578216 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 548/340.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638640 | Seeram et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Navindra P. Seeram (Los Angeles, California); David Heber (Los Angeles, California) |
ABSTRACT | Compositions of purified and biologically active ellagitannins are provided by separation from pomegranate husk using a method of extraction and purification using a solid polymeric adsorbent and the uses of the said compounds. |
FILED | Thursday, March 30, 2006 |
APPL NO | 11/395447 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 549/278 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638678 | Hoyer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Arizona Board of Regents (Tucson, Arizona) |
INVENTOR(S) | Patricia B. Hoyer (Tucson, Arizona); Loretta P. Mayer (Flagstaff, Arizona) |
ABSTRACT | The present invention relates to an animal model for human perimenopause and menopause. Also provided by the present invention are methods of making the animal model and methods of screening using the model. Also provided are methods of inducing ovarian failure in animals such as pets and wildlife. |
FILED | Friday, August 29, 2003 |
APPL NO | 10/650799 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639362 | Ye et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Jing Yong Ye (Ann Arbor, Michigan); Yunbo Guo (Ann Arbor, Michigan); Theodore B. Norris (Dexter, Michigan); James R. Baker, Jr. (Ann Arbor, Michigan) |
ABSTRACT | A photonic crystal sensor for outputting an output signal using a light source. The photonic crystal sensor includes a photonic crystal structure and a defect member disposed adjacent the photonic crystal structure. The defect member defines an operative surface. An input light signal from the light source is inputted to the photonic crystal structure and defect member and is internally reflected to thereby output the output signal. Also, the output signal relates to a condition at the operative surface. |
FILED | Wednesday, July 25, 2007 |
APPL NO | 11/881040 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/445 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07640114 | Showe et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
INVENTOR(S) | Louise C. Showe (Media, Pennsylvania); Michael K. Showe (Media, Pennsylvania); Laszlo Kari (Hamilton, Montana); Michael Nebozhyn (Yeadon, Pennsylvania); Andrey Loboda (Philadelphia, Pennsylvania) |
ABSTRACT | A method of developing a gene expression profile indicative of the presence or stage of a selected a disease, disorder or genetic pathology in a mammalian subject employs penalized discriminant analysis with recursive feature elimination. A method of diagnosing a cancer in a mammalian subject includes the steps of examining a sample containing the subject's immune cells and detecting a variance in the expression of a statistically significant number of genes, e.g., at least 10 non-tumor genes from those same genes in a characteristic disease or healthy gene expression profile. A significant variance in expression of these genes when compared to a gene expression profile, preferably an average gene expression profile of a normal control, or significant similarities to an average gene profile of subjects with cancer, correlates with a specific type of cancer and/or location of tumor. |
FILED | Friday, May 21, 2004 |
APPL NO | 10/558252 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07637122 | Turner et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho) |
ABSTRACT | Apparatuses and methods are provided for producing liquefied gas, such as liquefied natural gas. In one embodiment, a liquefaction plant may be coupled to a source of unpurified natural gas, such as a natural gas pipeline at a pressure letdown station. A portion of the gas is drawn off and split into a process stream and a cooling stream. The cooling stream may sequentially pass through a compressor and an expander. The process stream may also pass through a compressor. The compressed process stream is cooled, such as by the expanded cooling stream. The cooled, compressed process stream is expanded to liquefy the natural gas. A gas-liquid separator separates the vapor from the liquid natural gas. A portion of the liquid gas may be used for additional cooling. Gas produced within the system may be recompressed for reintroduction into a receiving line. |
FILED | Thursday, September 28, 2006 |
APPL NO | 11/536477 |
ART UNIT | 3744 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Refrigeration 062/611 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07637457 | Bennett |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Charles L. Bennett (Livermore, California) |
ABSTRACT | A solar thermal powered aircraft powered by heat energy from the sun. A Rankine-Brayton hybrid cycle heat engine is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller or other mechanism for enabling sustained free flight. The Rankine-Brayton engine has a thermal battery, preferably containing a lithium-hydride and lithium mixture, operably connected to it so that heat is supplied from the thermal battery to a working fluid. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat. |
FILED | Thursday, March 29, 2007 |
APPL NO | 11/731253 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/59 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07637967 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
INVENTOR(S) | Keqin Huang (Export, Pennsylvania); Harold D. Harter (Munhall, Pennsylvania); Paul G. Turkal (McMurray, Pennsylvania) |
ABSTRACT | The present invention provides for a method of depositing a stepped-gradient fuel electrode onto a fuel cell support 2 and the resulting fuel cell, that comprises placing a solid oxide fuel cell support that has at least an air electrode layer 4 and an electrolyte layer 6 into an atmospheric plasma spraying chamber and measuring spray parameters of an atmospheric plasma spray to obtain reactive oxides, conductive metal and graphite phases. Then spraying the spray parameters onto the solid oxide fuel cell support to produce multiple sub-layers 8 on the solid oxide fuel cell support, and adjusting a hydrogen usage of the atmospheric plasma spray. The adjusting of the hydrogen usage comprises using high hydrogen levels for the initial spraying of the sub-layers producing a first gradient region, and a lower hydrogen level for subsequent spraying of the sub-layers, producing a second gradient region. |
FILED | Thursday, December 08, 2005 |
APPL NO | 11/298321 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Metal working 029/623.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638026 | Willit et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | James L. Willit (Batavia, Illinois); John P. Ackerman (Prescott, Arizona); Mark A. Williamson (Naperville, Illinois) |
ABSTRACT | This is a single stage process for treating spent nuclear fuel from light water reactors. The spent nuclear fuel, uranium oxide, UO2, is added to a solution of UCl4 dissolved in molten LiCl. A carbon anode and a metallic cathode is positioned in the molten salt bath. A power source is connected to the electrodes and a voltage greater than or equal to 1.3 volts is applied to the bath. At the anode, the carbon is oxidized to form carbon dioxide and uranium chloride. At the cathode, uranium is electroplated. The uranium chloride at the cathode reacts with more uranium oxide to continue the reaction. The process may also be used with other transuranic oxides and rare earth metal oxides. |
FILED | Wednesday, August 24, 2005 |
APPL NO | 11/215202 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/47 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638034 | Sansinena et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Jose-Maria Sansinena (Los Alamos, New Mexico); Antonio Redondo (Los Alamos, New Mexico); Virginia Olazabal (Los Alamos, New Mexico); Mark A. Hoffbauer (Los Alamos, New Mexico); Elshan A. Akhadov (Los Alamos, New Mexico) |
ABSTRACT | A barrier structure for use in an electrochemical stochastic membrane sensor for single molecule detection. The sensor is based upon inorganic nanopores having electrically tunable dimensions. The inorganic nanopores are formed from inorganic materials and an electrically conductive polymer. Methods of making the barrier structure and sensing single molecules using the barrier structure are also described. |
FILED | Thursday, September 21, 2006 |
APPL NO | 11/525329 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/775 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638182 | D'urso et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Brian R D'urso (Clinton, Tennessee); John T Simpson (Clinton, Tennessee) |
ABSTRACT | A microchannel glass article includes a glass body having a porous, spinodal nanostructure and defining at least one microchannel extending from a surface of the article substantially through the article. |
FILED | Friday, July 28, 2006 |
APPL NO | 11/460658 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/188 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638297 | Anderson et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | J. Christopher Anderson (San Francisco, California); Ning Wu (Brookline, Massachusetts); Stephen Santoro (Cambridge, Massachusetts); Peter G. Schultz (La Jolla, California) |
ABSTRACT | Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base codon. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with homoglutamines using these orthogonal pairs. |
FILED | Wednesday, July 07, 2004 |
APPL NO | 10/563686 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638300 | Schultz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peter Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason W. Chin (Cambridge, United Kingdom); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (Lancaster, Pennsylvania); Miro Pastrnak (San Diego, California) |
ABSTRACT | The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids. |
FILED | Wednesday, October 18, 2006 |
APPL NO | 11/583551 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638356 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Fan Yang (Somerset, New Jersey); Stephen R. Forrest (Ann Arbor, Michigan) |
ABSTRACT | An optoelectronic device and a method of fabricating a photosensitive optoelectronic device includes depositing a first organic semiconductor material on a first electrode to form a continuous first layer having protrusions, a side of the first layer opposite the first electrode having a surface area at least three times greater than an underlying lateral cross-sectional area; depositing a second organic semiconductor material directly on the first layer to form a discontinuous second layer, portions of the first layer remaining exposed; depositing a third organic semiconductor material directly on the second layer to form a discontinuous third layer, portions of at least the second layer remaining exposed; depositing a fourth organic semiconductor material on the third layer to form a continuous fourth layer, filling any exposed gaps and recesses in the first, second, and third layers; and depositing a second electrode on the fourth layer, wherein at least one of the first electrode and the second electrode is transparent, and the first and third organic semiconductor materials are both of a donor-type or an acceptor-type relative to second and fourth organic semiconductor materials, which are of the other material type. |
FILED | Tuesday, July 11, 2006 |
APPL NO | 11/483641 |
ART UNIT | 2815 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/82 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638410 | Nastasi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Michael A. Nastasi (Santa Fe, New Mexico); Lin Shao (College Station, Texas) |
ABSTRACT | The transfer of strained semiconductor layers from one substrate to another substrate involves depositing a multilayer structure on a substrate having surface contaminants. An interface that includes the contaminants is formed in between the deposited layer and the substrate. Hydrogen atoms are introduced into the structure and allowed to diffuse to the interface. Afterward, the deposited multilayer structure is bonded to a second substrate and is separated away at the interface, which results in transferring a multilayer structure from one substrate to the other substrate. The multilayer structure includes at least one strained semiconductor layer and at least one strain-induced seed layer. The strain-induced seed layer can be optionally etched away after the layer transfer. |
FILED | Monday, December 18, 2006 |
APPL NO | 11/641471 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638616 | Fidantsef et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
INVENTOR(S) | Ana Fidantsef (Davis, California); Michael Lamsa (Davis, California); Brian Gorre-Clancy (Elk Grove, California) |
ABSTRACT | The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences. |
FILED | Thursday, June 26, 2008 |
APPL NO | 12/147333 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639119 | Carrender et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Institute K1-53 (Richland, Washington) |
INVENTOR(S) | Curtis L. Carrender (Morgan Hill, California); Ronald W. Gilbert (Morgan Hill, California) |
ABSTRACT | A system and method of inventorying multiple objects utilizing a multi-level or a chained radio frequency identification system. The system includes a master tag and a plurality of upper level tags and lower level tags associated with respective objects. The upper and lower level tags communicate with each other and the master tag so that reading of the master tag reveals the presence and absence of upper and lower level tags. In the chained RF system, the upper and lower level tags communicate locally with each other in a manner so that more remote tags that are out of range of some of the upper and lower level tags have their information relayed through adjacent tags to the master tag and thence to a controller. |
FILED | Friday, September 28, 2007 |
APPL NO | 11/864112 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/10.420 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639359 | Chung et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicagoArgonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Seok-Hwan Chung (Rockville, Maryland); Axel F. Hoffmann (Chicago, Illinois); Samuel D. Bader (Oak Park, Illinois) |
ABSTRACT | A biosensor utilizing bio-functionalized magnetic nanoparticles is provided. An external magnetic field is applied to a suspension of magnetic nanoparticles. A linearly polarized incident light is applied to the suspension of magnetic nanoparticles. A photocurrent from polarized light scattering by bio-functionalized magnetic nanoparticles in liquid is detected. The magneto-optic sensing technique is applied to a micro-fluidic channel for rapid and sensitive detection with a small sample amount, and subsequent magnetic separation for detoxification. This technique is used for the detection of Brownian relaxation with time sweep as well as frequency sweep. The magneto-optical sensor enables rapidly detecting changes in local dynamic properties of the magnetic nanoparticles in liquids and magnetic modulation of ferromagnetic particles in liquid provides increased signal sensitivity. |
FILED | Friday, October 19, 2007 |
APPL NO | 11/875475 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/338 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639770 | Leung |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ka-Ngo Leung (Hercules, California) |
ABSTRACT | A cylindrical neutron generator is formed with a coaxial RF-driven plasma ion source and target. A deuterium (or deuterium and tritium) plasma is produced by RF excitation in a cylindrical plasma ion generator using an RF antenna. A cylindrical neutron generating target is coaxial with the ion generator, separated by plasma and extraction electrodes which contain many slots. The plasma generator emanates ions radially over 360° and the cylindrical target is thus irradiated by ions over its entire circumference. The plasma generator and target may be as long as desired. The plasma generator may be in the center and the neutron target on the outside, or the plasma generator may be on the outside and the target on the inside. In a nested configuration, several concentric targets and plasma generating regions are nested to increase the neutron flux. |
FILED | Tuesday, April 22, 2008 |
APPL NO | 12/107545 |
ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/159 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07637142 | Tsui et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Zyvex Labs (Richardson, Texas) |
INVENTOR(S) | Kenneth Tsui (Richardson, Texas); Aaron Geisberger (Phoenix, Arizona) |
ABSTRACT | An apparatus including a micro-mechanical calibration member having at least a portion that is elastically biasable away from a neutral position in response to mechanical contact. The apparatus may also include a fixed member proximate the micro-mechanical calibration member which may be referenced to automatically detect deflection of the micro-mechanical calibration member away from the neutral position. The micro-mechanical calibration member may also be configured to receive a micro-mechanical contacting member to provide the mechanical contact employed to bias the micro-mechanical calibration member away from the neutral position. |
FILED | Monday, August 14, 2006 |
APPL NO | 11/464423 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/1.790 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638346 | Schowalter et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
INVENTOR(S) | Leo J. Schowalter (Latham, New York); Joseph A. Smart (Mooresville, North Carolina); Shiwen Liu (Acton, Massachusetts); Kenneth E. Morgan (Castleton, New York); Robert T. Bondokov (Watervliet, New York); Timothy J. Bettles (Bethlehem, Pennsylvania); Glen A. Slack (Scotia, New York) |
ABSTRACT | Semiconductor structures and devices based thereon include an aluminum nitride single-crystal substrate and at least one layer epitaxially grown thereover. The epitaxial layer may comprise at least one of AlN, GaN, InN, or any binary or tertiary alloy combination thereof, and have an average dislocation density within the semiconductor heterostructure is less than about 106 cm−2. |
FILED | Monday, August 14, 2006 |
APPL NO | 11/503660 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/47 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638815 | D'Evelyn et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Momentive Performance Materials Inc. (Albany, New York) |
INVENTOR(S) | Mark Philip D'Evelyn (Niskayuna, New York); Dong-Sil Park (Niskayuna, New York); Steven Francis LeBoeuf (Schenectady, New York); Larry Burton Rowland (Scotia, New York); Kristi Jean Narang (Voorheesville, New York); Huicong Hong (Niskayuna, New York); Stephen Daley Arthur (Glenville, New York); Peter Micah Sandvik (Clifton Park, New York) |
ABSTRACT | A crystalline composition is provided. The crystalline composition may include gallium and nitrogen; and the crystalline composition may have an infrared absorption peak at about 3175 cm−1, with an absorbance per unit thickness of greater than about 0.01 cm−1. |
FILED | Tuesday, January 09, 2007 |
APPL NO | 11/621560 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07637960 | Cai et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Houston (Houston, Texas) |
INVENTOR(S) | Chengzhi Cai (Houston, Texas); Chi-Ming Yam (Stafford, Texas); Guoting Qin (Houston, Texas); Steven Pei (Houston, Texas); Qingkai Yu (Houston, Texas) |
ABSTRACT | Thin and short cantilevers possess both a low force constant and a high resonance frequency, thus are highly desirable for atomic force microscope (AFM) imaging and force measurement. According to some embodiments, the invention provides small silicon (Si) cantilevers integrated with a Si tip, for example fabricated from SOI wafers that are used for reducing the variation of thickness of the cantilevers. In one example, the fabrication process provided SOI chips containing 40 silicon cantilevers integrating with an ultra-sharp Si tip. The resolution of images obtained with these tips was much higher than those obtained with the commercial tips, while the force constants were much less, that is, more suitable for imaging soft samples. The availability of such SOI chips greatly facilitates large scale modification of the surfaces of the silicon cantilever tips with a monolayer of oligo(ethylene glycol) derivatives that resist the non-specific interactions with proteins, rendering them most suitable for imaging and measurement of biological samples. |
FILED | Wednesday, November 15, 2006 |
APPL NO | 11/599726 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/40 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639739 | Rose et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Kenneth Rose (Ojai, California); Rui Zhang (Fremont, California); Shankar Regunathan (Bellevue, Washington) |
ABSTRACT | A method is described for efficiently determining total end-to-end distortion of a pre-compressed data stream, such as video streams or other media streams, at the time of delivery over a lossy-network, and for providing adaptive error-resilient delivery schemes based on distortion estimates. The methods can be utilized with single or multilayer packet streams and are particularly well suited for video streams. By way of example, distortion estimates are performed by generating side-information at the time of data stream compression, wherein the side-information is used in conjunction with information about the network status to determine an estimated distortion for the group of packets when the data stream is transported over the network to a destination end. This estimation may be utilized within described resiliency techniques in which the error correction mechanism is selected in response to the estimated distortion, which may be additionally refined in reference to cost factors. |
FILED | Friday, November 01, 2002 |
APPL NO | 10/286364 |
ART UNIT | 2621 — Selective Visual Display Systems |
CURRENT CPC | Pulse or digital communications 375/240.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639868 | Regli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | William C. Regli (Philadelphia, Pennsylvania); Cheuk Yiu Ip (Hong Kong, China Hong Kong); Leonard Sieger (Philadelphia, Pennsylvania) |
ABSTRACT | A method of providing an automated classifier for 3D CAD models wherein the method provides an algorithm for learning new classifications. The method enables existing model comparison algorithms to adapt to different classifications that are relevant in many engineering applications. This ability to adapt to different classifications allows greater flexibility in data searching and data mining of engineering data. |
FILED | Wednesday, June 16, 2004 |
APPL NO | 10/869061 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/159 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07638284 | Estes et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); Board of Regents of the University of Texas (Austin, Texas) |
INVENTOR(S) | D. Mark Estes (League City, Texas); Amy Umbright (St. Louis, Missouri); Karen Haas (Durham, North Carolina) |
ABSTRACT | The invention provides an isolated and purified nucleic acid molecule encoding mammalian immunoglobulin A inducing protein (IGIP), and methods of using the IGIP nucleic acid molecule and IGIP, e.g., to prepare antibodies. Also provided is an anti-IGIP antibody and uses therefor. |
FILED | Tuesday, July 26, 2005 |
APPL NO | 11/189559 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638682 | St. Martin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
INVENTOR(S) | Steven K. St. Martin (Columbus, Ohio); Anne Dorrance (Wooster, Ohio); Ron J. Fioritto (Wooster, Ohio); Sue Ann Berry (Wooster, Ohio); Scott McIntyre (Wooster, Ohio); Marcia Feller (Nevada, Ohio) |
ABSTRACT | A soybean cultivar designated HFPR-5 is disclosed. The invention relates to the seeds of soybean cultivar HFPR-5, to the plants of soybean HFPR-5, to plant parts of soybean cultivar HFPR-5 and to methods for producing a soybean plant produced by crossing soybean cultivar HFPR-5 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean variety HFPR-5, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar HFPR-5 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing the cultivar HFPR-5 with another soybean cultivar. |
FILED | Friday, December 07, 2007 |
APPL NO | 11/952525 |
ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/312 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 07638319 | Cardozo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Timothy Cardozo (New York, New York); Susan Zolla-Pazner (New York, New York) |
ABSTRACT | Newly discovered structural characteristic of the gp120 V3 loop have resulted in a “rule” or algorithm, that is used in a method for determining whether a subject is infected with HIV-1 virus that expresses selectivity for CXCR4 or CCR5 chemokine receptors. A positively charged surface patch defined by V3 loop residues 11 and 24 or 25 at the base of the β-strands in the V3 loop and the homologous β2-β3 chemokine hairpin is responsible for CXCR4 receptor selection. Thus a method for detecting the presence of HIV-1 virus that is selective for X4-co-receptors in a subject infected with HIV-1 or suspected of being infected, from the amino acid sequence of at least a part of the HIV-1 gp120 V3 region peptide that includes residues 11, 24 and 25, or from the nucleotide sequence of a nucleic acid encoding said V3 region peptide, is disclosed. |
FILED | Tuesday, March 07, 2006 |
APPL NO | 11/369010 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D606910 | Malassigne et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the United States Department of Veterans Affairs (Washington, District of Columbia); Medical College of Wisconsin (Milwaukee, Wisconsin); University of South Florida (Tampa, Florida) |
INVENTOR(S) | Pascal Malassigne (White Fish Bay, Wisconsin); Jeffrey Harrow (Lutz, Florida); Robert Jensen (Milwaukee, Wisconsin); John Erdman (Sturtevant, Wisconsin) |
ABSTRACT | |
FILED | Thursday, June 05, 2008 |
APPL NO | 29/319243 |
ART UNIT | 2916 — Design |
CURRENT CPC | Transportation D12/132 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07639363 | Chao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Tien-Hsin Chao (Valencia, California); Hanying Znod (Arcadia, California) |
ABSTRACT | An Electro-Optic Imaging Fourier Transform Spectrometer (EOIFTS) for Hyperspectral Imaging is described. The EOIFTS includes an input polarizer, an output polarizer, and a plurality of birefringent phase elements. The relative orientations of the polarizers and birefringent phase elements can be changed mechanically or via a controller, using ferroelectric liquid crystals, to substantially measure the spectral Fourier components of light propagating through the EIOFTS. When achromatic switches are used as an integral part of the birefringent phase elements, the EIOFTS becomes suitable for broadband applications, with over 1 micron infrared bandwidth. |
FILED | Thursday, September 07, 2006 |
APPL NO | 11/518536 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/453 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07640116 | Duong et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Tuan Duong (Glendora, California); Margaret Ryan (Pasadena, California) |
ABSTRACT | The present invention relates to a space-invariant independent component analysis and electronic nose for detection of selective chemicals in an unknown environment, and more specifically, an approach to analysis of sensor responses to mixtures of unknown chemicals by an electronic nose in an open and changing environment. It is intended to fill the gap between an alarm, which has little or no ability to distinguish among chemical compounds causing a response, and an analytical instrument, which can distinguish all compounds present but with no real-time or continuous event monitoring ability. |
FILED | Thursday, September 07, 2006 |
APPL NO | 11/518535 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
US 07640223 | Birdwell et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | John Douglas Birdwell (Oak Ridge, Tennessee); Tse-Wei Wang (Oak Ridge, Tennessee); Dale V. Stansberry (Knoxville, Tennessee); Jared Pendleton (Knoxville, Tennessee) |
ABSTRACT | An item is organized and presented by displaying a table, wherein the table displays a plurality of data comprising analysis results characterizing the at least one item, and wherein an analysis result is based on a decision made by an expert system according to a rule base. Input is accepted from a source, wherein the input may cause the analysis results to be modified, and wherein the results may be modified by re-applying the rule base. In response to the input, an updated table is created, wherein the updated table comprises the modified analysis results. This updated table is then displayable. |
FILED | Thursday, November 16, 2006 |
APPL NO | 11/560566 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Artificial intelligence 76/47 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 07639628 | Kogge |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Notre Dame du lac (Notre Dame, Indiana) |
INVENTOR(S) | Peter M. Kogge (Granger, Indiana) |
ABSTRACT | A method that includes activating and deactivating two counts between an active state and not an active state such that no more than one count at a time is in an active state. The method also includes receiving a request packet of information that requires a reply and incrementing the count that is in an active state, and setting a flag in the request packet of information that requires a reply, the flag being set to correspond to the count that is in the active state. The method further includes receiving a reply packet of information corresponding to a previously received request packet of information, the reply packet of information having a flag setting corresponding to the previously received request packet of information, and decrementing the count that corresponds to the flag setting of the reply packet of information. A network is also disclosed. |
FILED | Friday, July 14, 2006 |
APPL NO | 11/457543 |
ART UNIT | 2416 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/252 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 07638346 | Schowalter et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
INVENTOR(S) | Leo J. Schowalter (Latham, New York); Joseph A. Smart (Mooresville, North Carolina); Shiwen Liu (Acton, Massachusetts); Kenneth E. Morgan (Castleton, New York); Robert T. Bondokov (Watervliet, New York); Timothy J. Bettles (Bethlehem, Pennsylvania); Glen A. Slack (Scotia, New York) |
ABSTRACT | Semiconductor structures and devices based thereon include an aluminum nitride single-crystal substrate and at least one layer epitaxially grown thereover. The epitaxial layer may comprise at least one of AlN, GaN, InN, or any binary or tertiary alloy combination thereof, and have an average dislocation density within the semiconductor heterostructure is less than about 106 cm−2. |
FILED | Monday, August 14, 2006 |
APPL NO | 11/503660 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/47 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07637161 | Vornbrock et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon UTD Inc. (Springfield, Virginia) |
INVENTOR(S) | Theodore J. Vornbrock (Takoma Park, Maryland); Benjamin Dolgin (Alexandria, Virginia) |
ABSTRACT | An acoustic sensor configured to detect sound waves traveling through a substrate in which the acoustic sensor is embedded. The acoustic sensor includes a piezoelectric element and mass configured to receive and react to sound waves in three dimensions. Also, methods of using the acoustic sensor to receive sound waves traveling through a substrate. |
FILED | Wednesday, April 19, 2006 |
APPL NO | 11/406361 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/587 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638503 | Hsieh-Wilson et al. |
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FUNDED BY |
|
APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Linda C. Hsieh-Wilson (San Marino, California); Sarah E. Tully (Pasadena, California); Ross Mabon (Princeton, New Jersey); Cristal I. Gama (Los Angeles, California) |
ABSTRACT | Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical conditions associated with neurological disorders using the compounds and compositions provided herein. |
FILED | Thursday, May 26, 2005 |
APPL NO | 11/140618 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/53 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07638607 | Vale, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
INVENTOR(S) | Wylie Walker Vale, Jr. (La Jolla, California); Teresa M Reyes (Encinitas, California); Paul E Sawchenko (Carlsbad, California); Jean E F Rivier (La Jolla, California); Kathy A Lewis (San Diego, California); John B Hogenesch (Encinitas, California); Joan M Vaughan (San Diego, California); Marilyn H Perrin (La Jolla, California) |
ABSTRACT | A human urocortin-related peptide with significant sequence homology to the CRF neuropeptide family was identified. A mouse CDNA was isolated from whole brain poly (A+) RNA that encodes a predicted 38 amino acid peptide protein designated herein as urocortin II. Both human URP and mouse Ucn II are structurally related to the other known mammalian family members, CRF and urocortin (Ucn). These peptides are involved in the regulation of the hypothalamic-pituitary-adrenal axis under basal and stress conditions, suggesting a similar role for URP and Ucn IL Synthesized Ucn-II and URP peptide binds with higher affinity to CRF-R2 than to CRF-R1 Ucn II and human URP appear to be involved in the regulation of body temperature and appetite and may play a role in other stress related phenomenon. These findings identify Ucn II and human URP as a new members of the CRF family of neuropeptides, which are expressed centrally and bind to CRF-R2. |
FILED | Thursday, April 05, 2007 |
APPL NO | 11/784317 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/399 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07639662 | Young |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
INVENTOR(S) | C. David Young (Plano, Texas) |
ABSTRACT | A communications system is disclosed. The communication system includes a plurality of transceiver nodes configured to utilize a time division multiple access structure to communicate between the transceiver nodes. Each of the transceiver nodes generates congestion metric information based on the utilization of a link to each of its neighbors. A time division multiple access structure that includes a plurality of time slots during which the transceiver nodes are configured to communicate data cells is also disclosed. The data cells are transmitted from a transmission queue. The data cells include routing information and the congestion metric information. |
FILED | Friday, September 19, 2003 |
APPL NO | 10/666772 |
ART UNIT | 2617 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/345 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 29, 2009.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2009/fedinvent-patents-20091229.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page