FedInvent™ Patents
Patent Details for Tuesday, February 16, 2010
This page was updated on Monday, March 27, 2023 at 01:48 AM GMT
Department of Health and Human Services (HHS)
| US 07662114 | Seip et al. |
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| ASSIGNEE(S) | Focus Surgery, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Ralf Seip (Indianapolis, Indiana); Wo-Hsing Chen (Fishers, Indiana); Narendra T. Sanghvi (Indianapolis, Indiana) |
| ABSTRACT | Ultrasound transducers are disclosed which focus acoustic energy at various focal locations while minimizing focal spot degradation and the generation of unwanted on-axis or off-axis energy concentrations through using a generally constant f-number at the various focal locations. |
| FILED | Wednesday, March 02, 2005 |
| APPL NO | 11/070371 |
| ART UNIT | 3768 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery: Kinesitherapy 61/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662115 | Leismer |
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| INVENTOR(S) | Jeffrey M. Leismer (Gainesville, Florida) |
| ABSTRACT | A device for non-invasively mechanically stimulating bone or muscle includes a vibrational energy generator for applying vibrational energy to a first end of a length of a tissue which includes bone and/or muscle. The vibrational energy is for inducing strain in at least one region within the length of tissue. A restraint is disposed opposite the first end of the length to resist translation of the length during operation of the device and to provide loading to the bone or muscle. A connecting structure couples the restraint to the vibrational energy generator. The device does not require gravity to operate and as a result is expected to have applications in space, such as with astronauts, with those having bone ailments such as bed-ridden patients, persons with osteoporosis or disuse atrophy, athletes, recovering bone cancer patients, and persons with muscoskeletal disorders. |
| FILED | Monday, May 15, 2006 |
| APPL NO | 11/433988 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery: Kinesitherapy 61/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662361 | Au et al. |
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| INVENTOR(S) | Jessie L.-S. Au (Columbus, Ohio); M. Guillaume Wientjes (Columbus, Ohio) |
| ABSTRACT | The invention provides methods and compositions for modulating the activity of therapeutic agents for the treatment of a cancer by administering one or more agents that (either alone or in combination) induces telomere damage and inhibits telomerase activity in the cancer cell. The method initially uses, e.g., a telomere damage-inducing agent such as paclitaxel, and a telomerase inhibitory agent such as AZT. The invention also provides methods for identifying other agents with telomere damage-inducing activity and/or telomerase inhibitory activity (as well as and compositions having such activity), for use in the treatment of cancer. |
| FILED | Thursday, February 02, 2006 |
| APPL NO | 11/346405 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662362 | Kuppusamy et al. |
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| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Periannan Kuppusamy (New Albany, Ohio); Ramasamy P. Pandian (Columbus, Ohio); Narasimham L. Parinandi (Upper Arlington, Ohio); Jay L. Zweier (Blacklick, Ohio) |
| ABSTRACT | A new class of micro- and nano-particulate paramagnetic spin probes especially useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro. |
| FILED | Tuesday, September 07, 2004 |
| APPL NO | 10/935297 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662374 | Greene et al. |
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| ASSIGNEE(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mark I. Greene (Penn Valley, Pennsylvania); Hongtao Zhang (Paoli, Pennsylvania); Mark Richter (Philadelphia, Pennsylvania); Ramachandran Murali (Swarthmore, Pennsylvania) |
| ABSTRACT | Antibodies which bind to activated members of the erbB, TNF, and IgSF family of receptors and pharmaceutical compositions comprising the same are disclosed. Peptides and mimetics of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are also described. Methods of using such antibodies, peptides, and mimetics in tumor therapeutic, prophylactic, imaging and diagnostic applications are disclosed. |
| FILED | Monday, August 05, 2002 |
| APPL NO | 10/213292 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662382 | Cosgrove |
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| ASSIGNEE(S) | Boys Town National Research Hospital (Omaha, Nebraska) |
| INVENTOR(S) | Dominic Cosgrove (Omaha, Nebraska) |
| ABSTRACT | The present invention is directed to the identification and use of agents, particularly peptides and monoclonal antibodies that disrupt the interaction between Collagen XIII and α1β1 integrin. |
| FILED | Friday, February 08, 2008 |
| APPL NO | 12/069297 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/145.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662394 | Chang |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Gwong-Jen J. Chang (Fort Collins, Colorado) |
| ABSTRACT | The present invention encompasses isolated nucleic acids containing transcriptional units which encode a signal sequence of one flavivirus and an immunogenic flavivirus antigen of a second flavivirus or of a chimeric immunogenic flavivirus antigen comprising sequence from more than one flavivirus. The invention further encompasses a nucleic acid and protein vaccine and the use of the vaccine to immunize a subject against flavivirus infection. The invention also provides antigens encoded by nucleic acids of the invention, antibodies elicited in response to the antigens and use of the antigens and/or antibodies in detecting flavivirus or diagnosing flavivirus infection. |
| FILED | Thursday, April 04, 2002 |
| APPL NO | 10/500796 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662395 | Schlom et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Judith Kantor (Rockville, Maryland); James W. Hodge (Gaithersburg, Maryland) |
| ABSTRACT | The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition. |
| FILED | Wednesday, April 30, 2008 |
| APPL NO | 12/112819 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662396 | Paterson et al. |
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| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yvonne Paterson (Philadelphia, Pennsylvania); Nicholas Souders (Philadelphia, Pennsylvania); Duane Sewell (Cheltenham, Pennsylvania); Zhen-kun Pan (Wynnewood, Pennsylvania); Reshma Singh (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides recombinant polypeptides comprising an N-terminal fragment of an ActA protein or LLO protein fused to an antigen or a fragment thereof, nucleotides encoding same, recombinant vectors comprising same, and immunogenic and therapeutic methods utilizing same. |
| FILED | Monday, March 13, 2006 |
| APPL NO | 11/373528 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/200.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662397 | Krempl et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Christine D. Krempl (Wuerzburg, Germany); Peter L. Collins (Silver Spring, Maryland); Brian R. Murphy (Bethesda, Maryland); Ursula Buchholz (Silver Spring, Maryland); Stephen S. Whitehead (Montgomery Village, Maryland) |
| ABSTRACT | Recombinant respiratory syncytial virus (RSV) having the position of genes shifted within the genome or antigenome of the recombinant virus are infectious and attenuated in humans and other mammals. Gene shifted RSV are constructed by insertion, deletion or rearrangement of genes or genome segments within the recombinant genome or antigenome and are useful in vaccine formulations for eliciting an anti-RSV immune response. Also provided are isolated polynucleotide molecules and vectors incorporating a recombinant RSV genome or antigenome wherein a gene or gene segment is shifted to a more promoter-proximal or promoter-distal position within the genome or antigenome compared to a wild type position of the gene in the RSV gene map. Shifting the position of genes in this manner provides for a selected increase or decrease in expression of the gene, depending on the nature and degree of the positional shift. |
| FILED | Tuesday, February 08, 2005 |
| APPL NO | 11/054343 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/211.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662400 | Kita et al. |
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| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Hirohito Kita (Rochester, Minnesota); Jens Ponikau (Amherst, New York); Christopher Lawrence (Blacksburg, Virginia) |
| ABSTRACT | This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided. |
| FILED | Friday, October 13, 2006 |
| APPL NO | 11/580454 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/274.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662409 | Masters |
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| ASSIGNEE(S) | Gel-Del Technologies, Inc. (Saint Paul, Minnesota) |
| INVENTOR(S) | David B. Masters (Hastings, Minnesota) |
| ABSTRACT | The present invention relates to protein matrix materials and devices and the methods of making and using protein matrix materials and devices. More specifically the present invention relates to protein matrix materials and devices that may be utilized for various medical applications including, but not limited to, drug delivery devices for the controlled release of pharmacologically active agents, encapsulated or coated stent devices, vessels, tubular grafts, vascular grafts, wound healing devices including protein matrix suture material and meshes, skin/bone/tissue grafts, biocompatible electricity conducting matrices, clear protein matrices, protein matrix adhesion prevention barriers, cell scaffolding and other biocompatible protein matrix devices. Furthermore, the present invention relates to protein matrix materials and devices made by forming a film comprising one or more biodegradable protein materials, one or more biocompatible solvents and optionally one or more pharmacologically active agents. The film is then partially dried, rolled or otherwise shaped, and then compressed to form the desired protein matrix device. |
| FILED | Wednesday, February 28, 2001 |
| APPL NO | 09/796170 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/484 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662410 | Sligar et al. |
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| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen G. Sligar (Urbana, Illinois); Timothy H. Bayburt (Champaign, Illinois) |
| ABSTRACT | Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. Membrane scaffold proteins (MSP) assemble with target membrane or other hydrophobic or partially hydrophobic proteins or membrane fragments to form soluble nanoscale particles which preserve their native structure and function; they are improved over liposomes and detergent micelles. In the presence of phospholipid, MSPs form nanoscopic phospholipid bilayer disks, with the MSP stabilizing the particle at the perimeter of the bilayer domain. The particle bilayer structure allows manipulation of incorporated proteins in solution or on solid supports, including for use with such surface-sensitive techniques as scanning probe microscopy or surface plasmon resonance. The nanoscale particles facilitate pharmaceutical and biological research, structure/function correlation, structure determination, bioseparation, and drug discovery. |
| FILED | Tuesday, May 23, 2006 |
| APPL NO | 11/439466 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/499 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662547 | Wu et al. |
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| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Yuntao Wu (Manassas, Virginia); Rebecca Alyson Crook Yoder (Fairfax, Virginia); Jeremy Kelly (Arlington, Virginia); Dongyang Yu (Manassas, Virginia) |
| ABSTRACT | HIV infection can be detected by measuring phosphorylation levels of the actin-depolymerizing factor (AFD)/cofilin family, and infection can be treated and/or prevented by modulating the HIV co-receptor signaling pathway. |
| FILED | Friday, May 04, 2007 |
| APPL NO | 11/744776 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662549 | Markl et al. |
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| ASSIGNEE(S) | The University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Isabel D. C. Markl (San Francisco, California); Peter A. Jones (La Cañada, California); Yoshitaka Tomigahara (Osaka, Japan); Gangning Liang (Rowland Heights, California); Hualin Fu (Los Angeles, California); Jonathan Cheng (Monterey Park, California) |
| ABSTRACT | There is disclosed 103 novel methylation-altered DNA sequences (“marker sequences”) that have distinct methylation patterns in cancer, compared to normal tissue. In many instances, these marker sequences represent novel sequences not found in the GenBank data base, and none of these marker sequences have previously been characterized with respect to their methylation pattern in human cancers including, but not limited to those of bladder and prostate. These 103 sequences have utility as diagnostic, prognostic and therapeutic markers in the treatment of human cancer, and as reagents in kits for detecting methylated CpG-containing nucleic acids. |
| FILED | Friday, October 27, 2000 |
| APPL NO | 09/699243 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662556 | Shuman et al. |
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| ASSIGNEE(S) | Sloan Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Stewart Shuman (New York, New York); JoAnn Sekiguchi (Belmont, Massachusetts); Joseph Fernandez (Carlsbad, California); Robert Marcil (Carlsbad, California); James Hoeffler (Carlsbad, California); John Comiskey (Carlsbad, California) |
| ABSTRACT | The present invention provides a method of covalently joining a DNA strand to an RNA strand comprising (a) forming a topoisomerase-DNA intermediate by incubating a DNA cleavage substrate comprising a topoisomerase cleavage site with a topoisomerase specific for that site, wherein the topoisomerase-DNA intermediate has one or more 5′ single-strand tails; and (b) adding to the topoisomerase-DNA intermediate an acceptor RNA strand complementary to the 5′ single-strand tail under conditions permitting a ligation of the covalently bound DNA strand of the topoisomerase-DNA intermediate to the RNA acceptor strand and dissociation of the topoisomerase, thereby covalently joining the DNA strand to the RNA strand. The present invention also provides a method of tagging a 5′ end of an RNA molecule. The present invention further provides a DNA-RNA molecule which has been joined in vitro by the use of a topoisomerase. The present invention also provides a method of tagging a 5′ end of an mRNA. The present invention provides a method of isolating and cloning full-length gene sequences using capped mRNA after subtraction of non-capped RNA. |
| FILED | Friday, September 19, 2003 |
| APPL NO | 10/666486 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662563 | Gonzalgo et al. |
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| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Mark L. Gonzalgo (Livermore, California); Peter A. Jones (La Canada, California); Gangning Liang (Rowland Heights, California) |
| ABSTRACT | There is disclosed a cancer diagnostic method based upon DNA methylation differences at specific CpG sites. Specifically, the inventive method provides for a bisulfite treatment of DNA, followed by methylation-sensitive single nucleotide primer extension (Ms-SNuPE), for determination of strand-specific methylation status at cytosine residues. |
| FILED | Monday, May 01, 2006 |
| APPL NO | 11/415322 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662565 | Albino et al. |
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| ASSIGNEE(S) | Vector Tobacco, Inc. (Morrisville, North Carolina) |
| INVENTOR(S) | Anthony P. Albino (New York, New York); Ellen D. Jorgensen (South Salem, New York); Frank Traganos (Katonah, New York); Zbigniew Darzynkiewicz (Chappaque, New York); Wendy Jin (Chapel Hill, North Carolina) |
| ABSTRACT | Aspects of the invention concern methods for detecting, identifying and evaluating tobacco and tobacco products to determine the potential that these compositions have to contribute to a tobacco-related disease. It is based, at least in part; on the discovery that exposure of pulmonary cells to smoke or smoke condensate obtained from tobacco or tobacco products induces double stranded breaks in cellular DNA, which were efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX. |
| FILED | Wednesday, May 11, 2005 |
| APPL NO | 11/596088 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662569 | Targan et al. |
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| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Stephan R. Targan (Santa Monica, California); Eric A. Vasiliauskas (Manhattan Beach, California); William S. Mow (Culver City, California); Huiying Yang (Cerritos, California); Phillip R. Fleshner (Beverly Hills, California); Jerome I. Rotter (Los Angeles, California) |
| ABSTRACT | The invention provides a method of diagnosing or predicting susceptibility to a clinical subtype of Crohn's disease in a subject having Crohn's disease by determining the presence or absence of IgA anti-I2 antibodies in the subject, where the presence of the IgA anti-I2 antibodies indicates that the subject has a clinical subtype of Crohn's disease. In one embodiment, a method of the invention is practiced by further determining the presence or absence in the subject of a NOD2 variant, anti-Saccharomyces cerevisiae antibodies (ASCA), IgA anti-OmpC antibodies, or perinuclear anti-neutrophil cytoplasmic antibodies (pANCA). The methods of the invention can be used to diagnose or predict susceptibility to a clinical subtype of Crohn's disease, for example, a fibrostenotic subtype, a subtype characterized by the need for small bowel surgery, or a subtype characterized by the absence of features of ulcerative colitis. |
| FILED | Friday, April 11, 2003 |
| APPL NO | 10/413501 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662570 | Strauss et al. |
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| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Jerome F. Strauss (Wyndmoor, Pennsylvania); Mary D. Sammel (Wallingford, Pennsylvania); Rita Leite (Boothwyn, Pennsylvania); Amy Brown (Swarthmore, Pennsylvania) |
| ABSTRACT | The present invention provides methods of predicting or detecting labor in a female subject and methods of testing a compound for an ability to delay the onset of labor. The present invention also provides methods of testing a labor marker useful in the diagnostic methods, isolated peptides identified in the present invention, methods for inhibiting labor, utilizing the peptides, and kits comprising methods of the present invention. |
| FILED | Thursday, January 26, 2006 |
| APPL NO | 11/339816 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662573 | Ling et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Shari M. Ling (Ellicott City, Maryland); Lorah Perlee (Wilton, Connecticut); Velizar T. Tchernev (Sofia, Bulgaria); Serguei Lejnine (Mercer Island, Washington); Dhavalkumar D. Patel (Chapel Hill, North Carolina); Luigi Ferrucci (Baltimore, Maryland); Ming Zhan (Germantown, Maryland) |
| ABSTRACT | Methods are provided for evaluating osteoarthritis (OA), for example for diagnosing OA, to confirm a diagnosis of OA, to assess or prognose progression of OA, determining the severity of a subject who has OA, and determining a subject's risk of developing OA in the future, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes determining an amount of activity (such as an amount of protein present or an amount of expression) of OA risk-related molecules, such as soluble vascular adhesion protein 1 (sVAP-1) or interleukin-15 (IL-15). Also provided are methods of identifying one or more compounds that alter the activity of an OA-related molecule, thereby identifying potential anti-osteoarthritis drugs. |
| FILED | Friday, August 12, 2005 |
| APPL NO | 11/573711 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662579 | Fonseca et al. |
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| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Rafael Fonseca (Rochester, Minnesota); Philip R. Greipp (Rochester, Minnesota) |
| ABSTRACT | The invention provides methods and materials for determining a prognosis for myeloma and myeloma-disposed patients. The methods include the use of FISH techniques. The identification of the chromosomal abnormalities t(4;14)(p16;q32), t(14;16)(q32;q23), or 17p13 deletion (p53) in plasma cells from a patient indicates a poor prognosis. |
| FILED | Monday, November 10, 2003 |
| APPL NO | 10/705134 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662588 | Judd et al. |
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| ASSIGNEE(S) | The University of Montana (Missoula, Montana) |
| INVENTOR(S) | Ralph C. Judd (Florence, Montana); D. Scott Manning (Missoula, Montana) |
| ABSTRACT | Nucleic acid and amino acid sequences of the Omp85 proteins of N. gonorrhoeae and N. meningitidis, and fragments thereof are useful in vaccine compositions, therapeutic compositions and diagnostic compositions for use in the prevention, treatment and diagnosis of non-symptomatic gonococcal infection or symptomatic disease and non-symptomatic meningococcal infection and symptomatic disease. Antibodies are developed to these proteins and also useful in the compositions and methods described herein. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 11/605689 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662594 | Kong et al. |
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| ASSIGNEE(S) | New England Biolabs, Inc. (Ipswich, Massachusetts) |
| INVENTOR(S) | Huimin Kong (Wenham, Massachusetts); Myriam Vincent (Crenans, France); Yan Xu (Hamilton, Massachusetts) |
| ABSTRACT | Methods and a kit are provided for selectively and exponentially amplifying nucleic acids and include the use of a single strand helicase preparation or a thermostable helicase in the absence of a single strand binding protein and a DNA polymerase such that the amplification can be performed isothermally. |
| FILED | Thursday, January 05, 2006 |
| APPL NO | 11/327175 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662599 | Sherman et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Saint Paul, Minnesota); Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | David H. Sherman (Ann Arbor, Michigan); Nathan Magarvey (Minneapolis, Minnesota); Zachary Q. Beck (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides polypeptides involved in cryptophycin biosynthesis and the nucleic acid molecules that encode such polypeptides. The nucleic acid molecules and polypeptides of the invention or variants thereof can be used in the methods of the invention to produce cryptophycins. |
| FILED | Tuesday, March 27, 2007 |
| APPL NO | 11/691715 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662604 | Prabhakar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Vikas Prabhakar (Cambridge, Massachusetts); Ishan Capila (Ashland, Massachusetts); Rahul Raman (Arlington, Massachusetts); Carlos Bosques (Arlington, Massachusetts); Kevin Pojasek (Cambridge, Massachusetts); Ram Sasisekharan (Bedford, Massachusetts) |
| ABSTRACT | The invention relates to chondroitinase ABC I and uses thereof. In particular, the invention relates to recombinant and modified chondroitinase ABC I, their production and their uses. The chondroitinase ABC I enzymes of the invention are useful for a variety of purposes, including degrading and analyzing polysaccharides such as glycosaminoglycans (GAGs). These GAGs can include chondroitin sulfate, dermatan sulfate, unsulfated chondroitin and hyaluronan. The chondroitinase ABC I enzymes can also be used in therapeutic methods such as promoting nerve regeneration, promoting stroke recovery, treating spinal cord injury, treating epithelial disease, treating infections and treating cancer. |
| FILED | Wednesday, December 13, 2006 |
| APPL NO | 11/638287 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662619 | Kingsley et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | David H. Kingsley (Magnolia, Delaware); Joshua Zimmerberg (Bethesda, Maryland) |
| ABSTRACT | The present invention provides an isolated nucleic acid comprising the nucleotides set forth in the Sequence Listing as SEQ ID NO: 1. SEQ ID NO: 1 is an example of GP64-6His nucleic acid. The invention further provides polypeptides encoded by GP64-6His nucleic acids as well as the polypeptide encoded by SEQ ID NO: 2. The invention also provides liposomes comprising GP64-6His polypeptides as well as liposomes comprising GP64-6His polypeptides and biological molecules. The invention further provides a method of increasing the solubility of polypeptides comprising linking a 6His tag to a polypeptide and measuring the solubility of the 6His-tagged polypeptide, whereby an increase in solubility of the 6His-tagged polypeptide can be detected. The invention also provides a method of solubilizing a viral fusion polypeptide comprising linking a 6His tag to a viral fusion polypeptide. Further provided is a method of delivering a biological molecule to a cell comprising, administering the liposome comprising a GP64-6His polypeptide to a cell. This invention also provides a method of delivering a viral vaccine to a cell comprising administering the liposome comprising a GP64-6His polypeptide to a cell. Also provided is a method of delivering a DNA vaccine to a cell comprising administering the liposome comprising a GP64-6His polypeptide to a cell. Further provided is a GP64-6His polypeptide further comprising a binding site for a cell surface molecule. Also provided by this invention are chimeric proteins comprising GP64-6His. |
| FILED | Thursday, November 15, 2001 |
| APPL NO | 10/416979 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662642 | Kenten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wellstat BioCatalysis, LLC (Gaithersburg, Maryland) |
| INVENTOR(S) | John H. Kenten (Boyds, Maryland); Alfonso Tramontano (Rockville, Maryland); Aprile L. Pilon (Gaithersburg, Maryland); Gerald L. Lohnas (Catonsville, Maryland); Steven F. Roberts (Bethesda, Maryland) |
| ABSTRACT | Disclosed are epitope-containing heat shock fusion proteins, DNA constructs encoding such fusion proteins, and methods of use. More specifically, disclosed are ubiquitin fusion proteins comprising ubiquitin fused to a plurality of identical or non-identical epitopes at specified locations. |
| FILED | Tuesday, October 07, 2003 |
| APPL NO | 10/681388 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/503 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662644 | Hahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Klaus M. Hahn (San Diego, California); Alexei Toutchkine (San Diego, California); Rajeev Muthyala (Champaign, Illinois); Vadim Kraynov (San Diego, California); Steven J. Bark (San Diego, California); Dennis R. Burton (La Jolla, California); Chester Chamberlain (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides peptide synthons having protected functional groups for attachment of desired moieties (e.g. functional molecules or probes). Also provided are peptide conjugates prepared from such synthons, and synthon and conjugate preparation methods including procedures for identifying optimum probe attachment sites. Biosensors are provided having functional molecules that can locate and bind to specific biomolecules within living cells. Biosensors can detect chemical and physiological changes in those biomolecules as living cells are moving, metabolizing and reacting to its environment. Methods are included for detecting GTP activation of a Rho GTPase protein using polypeptide biosensors. When the biosensor binds GTP-activated Rho GTPase protein, an environmentally sensitive dye emits a signal of a different lifetime, intensity or wavelength than when not bound. New fluorophores whose fluorescence responds to environmental changes are also provided that have improved detection and attachment properties, and that can be used in living cells, or in vitro. |
| FILED | Monday, February 12, 2007 |
| APPL NO | 11/673909 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/546 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662750 | Hangauer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York); Roswell Park Cancer Institute (Buffalo, New York) |
| INVENTOR(S) | David G. Hangauer (East Amherst, New York); Tao Ji (Amherst, New York); Madison Lee (Buffalo, New York); Steven Pruitt (Williamsville, New York) |
| ABSTRACT | The present invention relates to 1,4-disubstituted naphthalene scaffold compounds and other closely related scaffold compounds. The present invention also relates to combinatorial libraries of such compounds. In addition, the present invention relates to a method of identifying a protein-protein interaction antagonist. The method first involves providing a compound as described herein. Next, the compound is contacted with interacting proteins of a protein-protein interaction target complex, whereby the compound is allowed to compete with the interacting proteins. Then, the activity of the compound for inhibiting formation of the protein-protein interaction target complex is measured. Finally, the compound that inhibits formation of the protein-protein interaction target complex is identified as a protein-protein interaction antagonist. Also disclosed is a method for modulating a protein-protein interaction. The method involves contacting interacting proteins of a protein-protein interaction target with a compound as described herein, whereby the protein-protein interaction between the interacting proteins is modulated. |
| FILED | Monday, December 06, 2004 |
| APPL NO | 11/005194 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662772 | Marchionni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Acorda Therapeutics, Inc. (Hawthorne, New York); Beth Israel Deaconess Medical Center (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mark Marchionni (Arlington, Massachusetts); Ralph Kelly (Chestnut Hill, Massachusetts); Beverly Lorell (Needham, Massachusetts); Douglas B. Sawyer (Brookline, Massachusetts) |
| ABSTRACT | The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646268 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662773 | James et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Biocon Limited (, India) |
| INVENTOR(S) | Kenneth D. James (Mebane, North Carolina); Balasingam Radhakrishnan (Chapel Hill, North Carolina); Navdeep B. Malkar (Cary, North Carolina); Mark A. Miller (Raleigh, North Carolina); Nnochiri N. Ekwuribe (Cary, North Carolina) |
| ABSTRACT | Modified natriuretic compounds and conjugates thereof are disclosed in the present invention. In particular, conjugated forms of hBNP are provided that include at least one modifying moiety attached thereto. The modified natriuretic compound conjugates retain activity for stimulating cGMP production, binding to NPR-A receptor, and in some embodiments an improved half-life in circulation as compared to unmodified counterpart natriuretic compounds. Oral, parenteral, subcutaneous, and intravenous forms of the compounds and conjugates may be prepared as treatments and/or therapies for heart conditions particularly congestive heart failure. Modifying moieties comprising oligomeric structures having a variety of lengths and configurations are also disclosed. Analogs of the natriuretic compound are also disclosed, having an amino acid sequence that is other than the native sequence. |
| FILED | Wednesday, November 26, 2003 |
| APPL NO | 10/723933 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662783 | Brooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Peter C. Brooks (Carmel, New York); Jennifer Roth (North Babylon, New York); Abebe Akalu (Forest Hills, New York) |
| ABSTRACT | The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured collagen type-IV with substantially greater affinity than to the native triple helical form of collagen type-IV. Methods utilizing such antagonists for therapeutic treatment of tumor growth, tumor metastasis or of restenosis also are described, as are methods to use such antagonists as diagnostic markers of angiogenesis in normal or diseased tissues both in vivo and ex vivo. The invention further describes methods for treating tumors using said antagonists in combination with radiation therapy and therapies comprising the antagonists and radiation treatment. |
| FILED | Friday, October 14, 2005 |
| APPL NO | 11/251442 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662785 | DeNardo et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of California (Oakland, California); Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Sally DeNardo (El Macero, California); Gerald DeNardo (El Macero, California); Rodney Balhorn (Livermore, California) |
| ABSTRACT | This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity. |
| FILED | Wednesday, February 09, 2005 |
| APPL NO | 11/055181 |
| ART UNIT | 1614 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662791 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Shi-Lung Lin (Alhambra, California); Cheng-Ming Chuong (Irvine, California); Randall B. Widelitz (Fullerton, California) |
| ABSTRACT | The present invention provides novel compositions and methods for suppressing the expression of a targeted gene using mRNA-cDNA duplexes. The invention further provides novel methods and compositions for generating amplified mRNA-cDNA hybrids, whose quantity is high enough to be used for the invention's gene silencing transfection. This improved RNA-polymerase chain reaction method uses thermocycling steps of promoter-linked double-stranded cDNA or RNA synthesis, in vitro transcription and then reverse transcription to amplify the amount of mRNA-cDNA hybrids up to two thousand folds within one round of the above procedure. |
| FILED | Wednesday, August 01, 2001 |
| APPL NO | 09/920342 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662793 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yukai He (Pittsburgh, Pennsylvania); Jennifer R. Grandis (Pittsburgh, Pennsylvania); Leaf Huang (Pittsburgh, Pennsylvania) |
| ABSTRACT | A nucleic acid is provided comprising an expression cassette which includes transcription control sequences of a member of a class of Pol III-transcribed genes in which no transcribed portion of the Pol III gene is required for transcription of the gene. In the expression cassette, the transcribed 5′ hairpin structure of the Pol III gene is deleted. The transcription control sequences are operably linked to a sequence of an EGFR gene in an antisense orientation suitable for decreasing expression of EGFR in the cell when transcribed. Lastly, a method for decreasing expression of EGFR in cells is provided that includes the step of contacting target cells either parenterally or directly into the tumor or tissue adjacent to the tumor cells with the nucleic acid of the present invention. |
| FILED | Wednesday, March 12, 2003 |
| APPL NO | 10/387252 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662795 | Rodriguez et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Ronald Rodriguez (Glenwood, Maryland); Ying Li (Gibson Island, Maryland) |
| ABSTRACT | The present invention relates to compositions and methods for enhancing the oncolytic activity of replication-competent, target cell-specific adenovirus vectors by modification of the E1A gene product. The target cell-specific replication-competent adenovirus vectors comprise a chimera of an adenovirus gene essential for replication, preferably an early gene, and the Androgen receptor (or a portion thereof) under the transcriptional control of a cell type-specific transcriptional regulatory element (TRE). By providing for cell type-specific transcription through the use of one or more cell type-specific TREs, the adenovirus vectors effect prostate-specific cytotoxicity due to selective replication. |
| FILED | Friday, August 08, 2003 |
| APPL NO | 10/523899 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662910 | Hammock et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bruce D. Hammock (Davis, California); In-Hae Kim (Davis, California); Christophe Morisseau (West Sacramento, California); Takaho Watanabe (Kanagawa-ken, Japan); John W. Newman (Davis, California); Paul Jones (Matawan, New Jersey); Sung Hee Hwang (Davis, California); Paul Whetstone (Davis, California) |
| ABSTRACT | Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases. |
| FILED | Thursday, October 20, 2005 |
| APPL NO | 11/256685 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662912 | Lacey |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Simon F. Lacey (Glendora, California) |
| ABSTRACT | The present invention relates to HLA-A*02-restricted cellular epitopes within the VP1 polypeptide of human polyomaviruses, which are useful as diagnostic reagents for virus infection. Preferred peptides correspond to amino acids residues 107-116, 108-116 and 44-52 of BKV VP1, and are processed in vivo in natural infection with BKV. Effector T cell populations stimulated by the peptides represent functional CTLs as assessed by cytotoxicity and cytokine production, and are reactive against cells presenting both the BKV peptides above and the JC virus homolog sequences. |
| FILED | Wednesday, November 19, 2008 |
| APPL NO | 12/273808 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662919 | Kitajewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jan Kitajewski (Ridgewood, New Jersey); Carrie Shawber (Washington Township, New Jersey); Yasuhiro Funahashi (New York, New York) |
| ABSTRACT | This invention provides a method for treating a subject having a tumor and a method for inhibiting angiogenesis in a subject, both comprising administering to the subject an effective amount of a composition of matter comprising the extracellular domain of a Notch receptor protein operably affixed to a half-life-increasing moiety. This invention also provides a composition of matter comprising the extracellular domain of Notch4 receptor protein operably affixed to a half-life-increasing moiety. This invention further provides an article of manufacture. Finally, this invention provides a replicable vector which encodes a polypeptide comprising the extracellular domain of a Notch receptor protein operably affixed to a half-life-increasing moiety, a host vector system which comprises such replicable vector and a method of producing such polypeptide. |
| FILED | Tuesday, April 26, 2005 |
| APPL NO | 11/114962 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662923 | Nelsestuen |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Saint Paul, Minnesota) |
| INVENTOR(S) | Gary L Nelsestuen (St. Paul, Minnesota) |
| ABSTRACT | The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described. |
| FILED | Thursday, November 02, 2006 |
| APPL NO | 11/555846 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/384 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662924 | Colamonici et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Oscar Colamonici (Chicago, Illinois); Shahid Siddiqui (Wilmette, Illinois) |
| ABSTRACT | The present invention provides β-subunit-Associated Regulator of Apoptosis, or BARA, polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, non-human transgenic animals, devices and methods for producing BARA polypeptides. The invention further provides compositions comprising BARA nucleic acids, polypeptides, and fusions or derivatives thereof. The invention further provides methods for treating, preventing, or ameliorating a medical disease, condition, or disorder comprising administering BARA or BARA compositions, as well as methods of diagnosing a pathological condition related to BARA. Still further, the invention provides methods of modulating levels of BARA expression and methods of determining whether a compound stimulates or inhibits BARA polypeptide activity or BARA polypeptide production. |
| FILED | Monday, November 07, 2005 |
| APPL NO | 11/267986 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662928 | Balthasar et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Joseph P. Balthasar (Lancaster, New York); Ryan J. Hansen (Carmel, Indiana); Feng Jin (Lockport, New York) |
| ABSTRACT | Antibodies to heavy chain of human FcRn are provided which function as non-competitive inhibitors of IgG binding to FcRn. The antibodies may be polyclonal, monoclonal, chimeric or humanized, or antigen binding fragments thereof. These antibodies are useful for reducing the concentration of pathogenic IgGs in individuals and therefore used as a therapeutic tool in autoimmune and alloimmune conditions. |
| FILED | Wednesday, December 06, 2006 |
| APPL NO | 11/634676 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662938 | Schinazi et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); The University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Raymond F. Schinazi (Decatur, Georgia); Dennis C. Liotta (McDonough, Georgia); Chung K. Chu (Athens, Georgia); J. Jeffrey McAtee (Atlanta, Georgia); Junxing Shi (Decatur, Georgia); Yongseok Choi (Athens, Georgia); Kyeong Lee (Athens, Georgia); Joon H. Hong (Athens, Georgia) |
| ABSTRACT | A class of 2′-fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formula: wherein Base is a purine or pyrimidine base; R1 is OH, H, OR3, N3, CN, halogen, including F, or CF3, lower alkyl, amino, lower alkylamino, di(lower)alkylamino, or alkoxy, and base refers to a purine or pyrimidine base; R2 is H, phosphate, including monophosphate, diphosphate, triphosphate, or a stabilized phosphate prodrug; acyl, or other pharmaceutically acceptable leaving group which when administered in vivo, is capable of providing a compound wherein R2 is H or phosphate; sulfonate ester including alkyl or aryalkyl sulfonyl including methanesulfonyl, benzyl, wherein the phenyl group is optionally substituted with one or more substituents as described in the definition of aryl given above, a lipid, an amino acid, peptide, or cholesterol; and R3 is acyl, alkyl, phosphate, or other pharmaceutically acceptable leaving group which when administered in vivo, is capable of being cleaved to the parent compound, or a pharmaceutically acceptable salt thereof. |
| FILED | Monday, November 19, 2007 |
| APPL NO | 11/942551 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/4.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662941 | Lemischka et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Princeton - Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Ihor R. Lemischka (Princeton, New Jersey); Christoph Schaniel (Princeton, New Jersey); Feng Li (Plainsboro, New Jersey); Xenla Schafer (Princeton, New Jersey); Patrick J. Paddison (Oyster Bay, New York) |
| ABSTRACT | The present invention relates to methods and compositions for assaying embryonic stem cell maintenance. In particular, the present invention provides reporter constructs for stem cell pluripotency and differentiation and cells and organisms containing such constructs. |
| FILED | Tuesday, January 17, 2006 |
| APPL NO | 11/332943 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662946 | Ginsburg et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | David Ginsburg (Ann Arbor, Michigan); Gallia Levy (Ann Arbor, Michigan); Han-Mou Tsai (Manhasset, New York) |
| ABSTRACT | The present invention relates to a disintegrin and metalloproteinase containing thrombospondin 1-like domains (ADAMTS) and in particular to a novel ADAMTS13 protease and to nucleic acids encoding ADAMTS13 proteases. The present invention encompasses both native and recombinant wild-type forms of ADAMTS13, as well as mutant and variant forms including fragments, some of which posses altered characteristics relative to the wild-type ADAMTS13. The present invention also relates to methods of using ADAMTS13, including for treatment of TTP. The present invention also relates to methods for screening for the presence of TTP. The present invention further relates to methods for developing anticoagulant drugs based upon ADAMTS13. |
| FILED | Friday, March 17, 2006 |
| APPL NO | 11/378752 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662969 | Doyle |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Michael P. Doyle (Glenn Dale, Maryland) |
| ABSTRACT | This invention relates to compositions and methods for achieving the efficient aziridination of organic molecules, especially olefins. More specifically, the invention is directed to a mild, selective, and efficient aziridination protocol that involves catalysis by a mixed-valent dirhodium(II,III) catalyst (Rh25+). Especially preferred sources for forming such mixed-valent dirhodium(II,III) catalyst (Rh25+) are dirhodium(II) carboxamidates, such as dirhodium(II) caprolactamate, and their derivatives and analogues. |
| FILED | Wednesday, March 15, 2006 |
| APPL NO | 11/375020 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662999 | Burns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | National Institutes of Health (NIH) (Bethesda, Maryland); The United States of America as represented by the Department of Health and Human Services (DHHS) (Washington, District of Columbia); U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR) (, None) |
| INVENTOR(S) | Mark R. Burns (Kenmore, Washington); Sunil A. David (Lawrence, Kansas) |
| ABSTRACT | Small molecule polycationic agents are used to modulate or interrupt biological processes by binding to oligosaccharide-based biomolecules. Compounds that inhibit nitric oxide, TNFα or other immunomodulators are provided and are useful for treating immunological disease and disease of an infectious disorder. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/693941 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 564/152 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664604 | Heine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | John J. Heine (New Port Richey, Florida); Robert P. Velthuizen (Livingston, New Jersey); Jerry Alan Thomas (Potomac, Maryland) |
| ABSTRACT | The present invention is a method of determining breast cancer risk including the steps of establishing a risk probably value associated with a patient, the risk probability value calculated from an array of risk factors associated with breast cancer, applying a computer algorithm adapted to find abnormalities in the patient's mammogram, and increasing the tolerance level for false positive results in the computer algorithm responsive to a higher probability value associated with the patient and decreasing the tolerance level for false positive results in the computer algorithm responsive to a lower probability value associated with the patient. |
| FILED | Monday, December 02, 2002 |
| APPL NO | 10/065929 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07661271 | Millsaps, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Knox T. Millsaps, Jr. (Monterey, California) |
| ABSTRACT | An integrated electric gas turbine comprises a compressor that includes a plurality of airfoils. An electric motor is arranged to drive the compressor, and a combustor is arranged to receive compressed air from the compressor and further arranged to receive a fuel input. A turbine is arranged to receive the combustion gases from the combustor. A generator is integrated with the turbine and arranged to provide a power output. A controller is connected between the generator and the electric motor and arranged to direct a portion of the power output from the generator to the electric motor. |
| FILED | Friday, March 18, 2005 |
| APPL NO | 11/086734 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/786 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661291 | McMahan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Lisa E. McMahan (Tampa, Florida); Joseph G. Protola (Clearwater, Florida); Bruce Wayne Castleman (Pinellas Park, Florida) |
| ABSTRACT | A method for enhancing the accuracy of a sensor is provided. The method includes determining a measure of the output of the sensor, determining whether the measure falls outside of an acceptable range for the output of the sensor, and, when the measure falls outside the acceptable range, modifying the measure of the output such that the measure falls within the acceptable range for the sensor. |
| FILED | Thursday, March 15, 2007 |
| APPL NO | 11/686751 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/1.380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661312 | Dukich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Peter J. Dukich (Blaine, Minnesota); Gregory A. Miller (Maple Grove, Minnesota) |
| ABSTRACT | An inertial measurement unit is described that includes a first subassembly comprising one or more inertial sensors, a second subassembly comprising support electronics for the one or more inertial sensors, and at least one pair of mating connectors configured to provide an interface between the first subassembly and the second subassembly. |
| FILED | Friday, June 30, 2006 |
| APPL NO | 11/427937 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/493 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661313 | Maguire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jason M. Maguire (Middetown, Rhode Island); Gregory H. Ames (Wakefield, Rhode Island) |
| ABSTRACT | An accelerometer is provided including a strain sensor with a substantially linear configuration. The strain sensor is mounted on a transducer such that the strain sensor extends laterally across the transducer. The transducer has a base and a plurality of flaps joined at a first end to the base and supporting the strain sensor at a second end. The flaps translate acceleration in a predefined direction to strain in the strain sensor. Further embodiments have flaps defining an interrupted surface with greater height at the center and flaps that have features for enhancing the strain caused by acceleration. |
| FILED | Monday, November 05, 2007 |
| APPL NO | 11/934846 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/514.160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661319 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Chang Liu (Winnetka, Illinois); Jonathan Engel (Minneapolis, Minnesota); Nannan Chen (Urbana, Illinois); Jack Chen (Fremont, California) |
| ABSTRACT | A micromachined artificial sensor comprises a support coupled to and movable with respect to a substrate. A polymer, high-aspect ratio cilia-like structure is disposed on and extends out-of-plane from the support. A strain detector is disposed with respect to the support to detect movement of the support. |
| FILED | Friday, June 01, 2007 |
| APPL NO | 11/809523 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/774 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661362 | Hennings et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Reynolds Systems, Inc. (Middletown, California) |
| INVENTOR(S) | George N Hennings (Ridgecrest, California); Richard K Reynolds (Calistoga, California); Christopher J Nance (Middletown, California) |
| ABSTRACT | An igniter assembly that includes a housing, a secondary explosive input charge, a pyrotechnic output charge and a barrier system that is disposed between the input charge and the pyrotechnic output charge. The barrier system shields the pyrotechnic output charge from energy released by the input charge to prevent the output charge from being cooked-off or initiated unless the input charge is detonated. |
| FILED | Thursday, September 25, 2008 |
| APPL NO | 12/237875 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/202.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661469 | O'Loughlin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | James P. O'Loughlin (Placitas, New Mexico) |
| ABSTRACT | A method of cooling a plurality of devices operated in parallel and heated by relatively long duration pulses using a single coolant flow channel to the devices in series that transports the heat from the several devices in a contiguous series of heat pulses to the heat exchanger. |
| FILED | Monday, April 28, 2008 |
| APPL NO | 12/110427 |
| ART UNIT | 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Heat exchange 165/269 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661483 | Mulukutla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | NanoScale Corporation (Manhattan, Kansas) |
| INVENTOR(S) | Ravichandra S. Mulukutla (Manhattan, Kansas); Paul S. Malchesky (Painesville, Ohio); Ronaldo Maghirang (Manhattan, Kansas); John S. Klabunde (Manhattan, Kansas); Kenneth J. Klabunde (Manhattan, Kansas); Olga Koper (Manhattan, Kansas) |
| ABSTRACT | Methods of reducing smoke levels in smoke-affected areas, reducing the level of toxic compounds produced by fires, fire suppression, and increasing flame retardancy. In particular, methods according to the present invention comprise dispersing nanocrystalline particles in the areas affected by smoke for sorption of smoke particulates and toxic compounds produced from a fire. The nanocrystalline particles are also effective for use in methods of fire suppression and flame retardancy. |
| FILED | Wednesday, August 22, 2007 |
| APPL NO | 11/843330 |
| ART UNIT | 1796 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Fire extinguishers 169/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662024 | Bechtold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | V.I. Mfg. Inc. (Ontario, New York) |
| INVENTOR(S) | Michael J. Bechtold (Ontario, New York); Darryle E. Fowler (Shortville, New York); David E. Mohring (Pittsford, New York); Thomas Williams (Webster, New York); Robert Henderson (Livonia, New York); Alex DiNicola (Webster, New York); Christopher Wood (Webster, New York); Joseph P. Meisenzahl (Webster, New York); Scott Bambrick (Rochester, New York) |
| ABSTRACT | A polishing apparatus comprising a base for affixing structures thereto, a drive wheel, a polishing wheel assembly, a polishing belt, and at least one routing wheel engaged with the polishing belt. The polishing wheel assembly includes an elongated arm including a distal end, and a rotatable polishing wheel supported at the distal end of the elongated arm. The polishing belt is made with an abrasive outer surface to perform the polishing, and an inner surface for engagement with the perimeters of the drive wheel and the polishing wheel. The routing wheel is engaged with the outer surface of the polishing belt, such that the contact arc of the polishing belt with the polishing wheel differs from an arc of the polishing wheel perimeter extending from a first tangent line between the drive wheel and the polishing wheel to a second tangent line between the drive wheel and the polishing wheel. |
| FILED | Wednesday, May 02, 2007 |
| APPL NO | 11/743333 |
| ART UNIT | 3727 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Abrading 451/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662265 | Chiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); A123 Systems, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Yet-Ming Chiang (Framingham, Massachusetts); Benjamin Hellweg (London, United Kingdom); Richard K. Holman (Belmont, Massachusetts); Steven M. Tobias (Cambridge, Massachusetts); Dong-Wan Kim (Cambridge, Massachusetts); Ryan Craig Wartena (Cambridge, Massachusetts) |
| ABSTRACT | Methods are provided for making bipolar electrochemical devices, such as batteries, using electrophoresis. A bipolar device is assembled by applying a field that creates a physical separation between two active electrode materials, without requiring insertion of a discrete separator film or electrolyte layer. |
| FILED | Monday, April 18, 2005 |
| APPL NO | 11/108602 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/491 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662309 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Jye-Shane Yang (Ping-Chen, Taiwan); Vance Williams (Vancouver, Canada); Yijun Miao (Reston, Virginia); Claus G. Lugmair (San Jose, California); Igor A. Levitsky (Fall River, Massachusetts); Jinsang Kim (Ann Arbor, Michigan); Robert Deans (Grafton, Massachusetts) |
| ABSTRACT | The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer. |
| FILED | Monday, October 17, 2005 |
| APPL NO | 11/252419 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions 252/301.350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662545 | Nuzzo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); William R. Childs (Champaign, Illinois); Michael J. Motala (Champaign, Illinois); Keon Jae Lee (Savoy, Illinois) |
| ABSTRACT | A method of making a microstructure includes selectively activating a portion of a surface of a silicon-containing elastomer, contacting the activated portion with a substance, and bonding the activated portion and the substance, such that the activated portion of the surface and the substance in contact with the activated portion are irreversibly attached. The selective activation may be accomplished by positioning a mask on the surface of the silicon-containing elastomer, and irradiating the exposed portion with UV radiation. |
| FILED | Thursday, October 14, 2004 |
| APPL NO | 10/965279 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662568 | O'Leary et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Timothy J. O'Leary (Silver Spring, Maryland); Jeffrey T. Mason (Gaithersburg, Maryland) |
| ABSTRACT | Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection. |
| FILED | Friday, March 06, 2009 |
| APPL NO | 12/399060 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662669 | Chang-Chien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Space and Mission Systems Corp. (Los Angeles, California) |
| INVENTOR(S) | Patty Pei-Ling Chang-Chien (Redondo Beach, California); Kelly Jill Tornquist Hennig (Torrance, California); Ken Wai-Kin Ho (Alhambra, California); Ann Kent-Ming Ho (Temple City, California) |
| ABSTRACT | A method for fabricating wafer-level packages including lateral interconnects. The method includes precutting a cover wafer at the locations where the cover wafer will be completely cut through to separate the wafer-level packages. The cover wafer is bonded to the substrate wafer using bonding rings so as to seal the integrated circuit within a cavity between the cover wafer and the substrate wafer, where the precuts face the substrate wafer. The cover wafer is then cut at the precut locations to remove the unwanted portions of the cover wafer between the packages and expose contacts or probe pads for the lateral interconnects. The substrate wafer is then cut between the wafer-level packages to separate the packages. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 11/782488 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/113 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662682 | Saxler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Adam William Saxler (Durham, North Carolina); Edward Lloyd Hutchins (Raleigh, North Carolina) |
| ABSTRACT | A method for epitaxial growth of Group III nitrides on a substrate using source gases consistent with metal organic chemical vapor deposition is provided. A heterostructure formed from two Group III nitride epitaxial layers is grown on a substrate in an atmosphere containing minimal hydrogen. The two Group III nitride epitaxial layers differ sufficiently in composition from one another in order to generate a two-dimensional electron gas at their interface. The substrate upon which the heterostructure is grown has a diameter of at least 100 mm. |
| FILED | Monday, May 12, 2008 |
| APPL NO | 12/118947 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662751 | Abbott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Justin J. Skaife (Lafayette, California) |
| ABSTRACT | Detection apparatus for use in the detection of the presence of a selected pathogen in a sample are disclosed. Such apparatus include: a substrate with a detection region on a surface thereof, the detection region having microstructures including grooves formed therein that will align liquid crystal material in contact therewith, the width and depth of the grooves being in the range of 10 μm or less; a blocking layer on the surface of the detection region of the substrate that does not disrupt the alignment of liquid crystal material in contact therewith, the blocking layer blocking nonspecific adsorption of pathogens to the surface; and a binding agent on the surface of the detection region of the substrate, the binding agent specifically binding the selected pathogen. |
| FILED | Friday, September 03, 2004 |
| APPL NO | 10/934023 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662842 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Ohio State Univesity Research Foundation (Columbus, Ohio); The University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Duane D. Miller (Germantown, Tennessee); James T. Dalton (Columbus, Ohio); Veeresa Gududuru (Memphis, Tennessee); Eunju Hurh (Camarillo, California) |
| ABSTRACT | Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides according to formulae (I) and (II) are disclosed where the various substituent groups are as defined in the specification. Methods of making these compounds, pharmaceutical compositions containing the compounds, and their use, particularly for treating or preventing cancer, are also disclosed. |
| FILED | Wednesday, July 19, 2006 |
| APPL NO | 11/458648 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/369 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663269 | Laughlin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | A-TECH Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Darren R. Laughlin (Albuquerque, New Mexico) |
| ABSTRACT | A printed circuit board (PCB) coil linear actuator is disclosed. The actuator includes a coil assembly and a magnet assembly. The coil assembly includes a plurality of PCB coils electrically connected in series. The PCB coils arranged in a row and adjacent PCB coils are separated by a gap. Each PCB coil includes a low aspect ratio, multi-layer coil member disposed on a board member. The actuator assembly includes a plurality of magnet units arranged in a row, wherein adjacent magnet units are separated by a gap. When the actuator is assembled, the PCB coils arranged in alternating sequence with the magnet units. The PCB coil linear actuator is intended to replace traditional slotted bobbin voice coil actuators (VCAs) and is particularly useful in fast steering mirror (FSM) applications. The PCB coil linear actuator provides many advantages over a VCA of an equivalent motor constant, including improved performance, lower weight and a lower profile. |
| FILED | Wednesday, December 13, 2006 |
| APPL NO | 11/610280 |
| ART UNIT | 2839 — Optics |
| CURRENT CPC | Electrical generator or motor structure 310/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663288 | Chandrashekhar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | M V S Chandrashekhar (Ithaca, New York); Christopher Ian Thomas (Ithaca, New York); Michael G. Spencer (Ithaca, New York) |
| ABSTRACT | High aspect ratio micromachined structures in semiconductors are used to improve power density in Betavoltaic cells by providing large surface areas in a small volume. A radioactive beta-emitting material may be placed within gaps between the structures to provide fuel for a cell. The pillars may be formed of SiC. In one embodiment, SiC pillars are formed of n-type SiC. P type dopant, such as boron is obtained by annealing a borosilicate glass boron source formed on the SiC. The glass is then removed. In further embodiments, a dopant may be implanted, coated by glass, and then annealed. The doping results in shallow planar junctions in SiC. |
| FILED | Thursday, August 24, 2006 |
| APPL NO | 11/509323 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/303 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663342 | Kimball et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | SolarBridge Technologies, Inc. (Champagne, Illinois) |
| INVENTOR(S) | Jonathan W. Kimball (Mahomet, Illinois); Philip T. Krein (Champaign, Illinois); Nicholas D. Benavides (Champaign, Illinois) |
| ABSTRACT | In an electrical power supply having a plurality of switching power converter circuits and configured to supply a voltage to an electrical load, a method of controlling a duty cycle of at least one switch of one of the plurality of switching power converter circuits includes determining a storage voltage produced by the one of the plurality of energy storage devices. The method further includes determining an average storage voltage corresponding to an average of storage voltages produced by each of the plurality of energy storage devices. The method further includes determining at least one control signal as a function of the storage voltage, the average storage voltage, and a reference voltage. The method further includes controlling the duty cycle of the at least one switch of the one of the plurality of switching power converter circuits based upon the at least one control signal. |
| FILED | Friday, January 26, 2007 |
| APPL NO | 11/627731 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663528 | Malakian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Kourken Malakian (Mount Laurel, New Jersey); Sabrina M. Chowdhury (Mount Laurel, New Jersey) |
| ABSTRACT | A hostile missile engager senses the missile and supplies kinematic data to an interceptor missile fire control processor, which predicts the target's future location with the aid of a powered/unpowered identifier. The identifier passes the kinematic data through filters having lags for powered and unpowered operation, to produce residuals and residual covariances. The probabilities of powered and unpowered motion are determined, and thresholded. If the probability of powered motion or unpowered motion exceeds its threshold, the motion is deemed known. If the target is deemed to be powered, a set of the three-dimensional kinematic features is applied to a nine-state Kalman filter to produce an optimal state. If the target missile is unpowered, a set of the three-dimensional kinematic features corresponding to the second lag is applied to a six-state Kalman filter to produce an optimal state for the unpowered motion. The optimal states control the interceptor toward the target. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/051892 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663546 | Miyamoto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Ryan Y. Miyamoto (Honolulu, Hawaii); Derek M. K. Ah Yo (Honolulu, Hawaii); Joseph M. Cardenas (Honolulu, Hawaii); Donald J. Harbin (Mililani, Hawaii); Luke B. Joseph (Honolulu, Hawaii); Ken C. K. Cheung (Kailua, Hawaii) |
| ABSTRACT | A phased array satellite communication (SATCOM) system for ground stations receives information signals and a beam from a satellite and autonomously steers communication signals by phase information toward a satellite extracted from the received satellite beam. The new phased array eliminates the need for phase shifters to control a beam. The new phased array satellite communications system avoids delay in digital signal processing or feedback systems to find satellite locations, enabling autonomous real-time electronic beam steering with no delay. The new system is also used to handle signals from and to multiple satellites simultaneously. The new system is useful in other applications where an enhanced point-to-point communication link is required. |
| FILED | Friday, June 23, 2006 |
| APPL NO | 11/474126 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663548 | McKay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | James P. McKay (Hermosa Beach, California); Gan-Tai Tseng (Rancho Palos Verdes, California) |
| ABSTRACT | A receiving system includes a combiner configured to receive signals from two or more antenna elements and to generate sum and difference outputs, and a switch configured to sequentially provide the sum and difference outputs as inputs to a receiver. |
| FILED | Friday, March 24, 2006 |
| APPL NO | 11/277470 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/424 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663618 | Svensson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Lars G. Svensson (Gothenburg, Sweden); William C. Athas (Redondo Beach, California); Rajat K. Lal (Culver City, California) |
| ABSTRACT | Power-efficient, pulsed driving of capacitive loads to controllable voltage levels, with particular applicability to LCDs. Energy stored in a portion of the capacitive load is recovered during a recovery phase. Time-varying signals are used to drive the load and to recover the stored energy, thus minimizing power losses, using processes named adiabatic charging and adiabatic discharging. |
| FILED | Friday, November 18, 2005 |
| APPL NO | 11/283292 |
| ART UNIT | 2629 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/211 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664120 | Hershey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Stephen P. Hershey (Aurora, Colorado) |
| ABSTRACT | In certain embodiments, a first node among a plurality of distributed nodes capable of forming or reforming a communication network between the nodes, each of the nodes including one or more transceivers, includes a memory for storing values for variables for the first node and includes a plurality of transceivers. The first node is operable to: (1) spontaneously and independent of a centralized controller associated with the network, transmit a probe message for purposes of forming or reforming a network; (2) receive a probe message from a second node for purposes of forming or reforming a network, the probe message including values for variables for the second node; (3) compare the values for the variables for the first node to the values for the variables for the second node within the probe message to determine, independent of a centralized controller associated with the network, whether the first node should set a home channel of one of its transceivers to a new channel; and (4) if so, set the home channel of a determined one of the transceivers of the first node to the new channel. |
| FILED | Tuesday, September 27, 2005 |
| APPL NO | 11/237990 |
| ART UNIT | 2416 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664144 | Fanson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Edgewater Computer Systems, Inc. (, Canada) |
| INVENTOR(S) | John Fanson (Ottawa, Canada); Yu Wang (Kanata, Canada) |
| ABSTRACT | A synchronization system and method for use in a packet switched communication network are provided. The synchronization system comprises a transmitter-identification system, a packet-boundary detection system and a storage-access system. The transmitter-identification system enables each receiving terminal within the network to know the identity of the originating transmitter terminal for a given packet of information, prior to the reception of this packet of information. The packet-boundary detection system enables detection of packet synchronization parameters for all transmitter-receiver pairs of terminals within the network. The storage-access system stores the detected packet synchronization parameters and allows the receiver to access the packet synchronization parameters. According to one embodiment of the invention, the synchronization method comprises the step of detecting synchronization parameters and, for a given receiver terminal, establishing the identity of the originating transmitter for an incoming packet of information, accessing synchronization parameters corresponding to the identified transmitter, adjusting receiver based on accessed synchronization parameters and decoding the incoming packet of information. |
| FILED | Thursday, December 21, 2006 |
| APPL NO | 11/614875 |
| ART UNIT | 2416 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/503 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664149 | Diels et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC. UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Jean-Claude Diels (Albuquerque, New Mexico); Ladan Arissian (Albuquerque, New Mexico) |
| ABSTRACT | Apparatus, systems, and methods are provided that utilize a material inserted into a laser cavity such that the material has an optical length that varies as the laser cavity varies to keep the repetition rate constant. The material may provide auto-stabilization of the optical output form the laser cavity. |
| FILED | Tuesday, May 08, 2007 |
| APPL NO | 11/745837 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664472 | Mosley, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | William H. Mosley, Jr. (Seminole, Florida); William E. Coleman, Jr. (Clearwater, Florida); Mark A. Gloudemans (Fort Wayne, Indiana); Bror W. Peterson (Murphy, Texas); Jayanti Patel (Saint Petersburg, Florida) |
| ABSTRACT | Reducing the peak-to-average power ratio of a signal comprises receiving the input signal, where the input signal is associated with at least one unacceptable frequency range. The input signal is clipped about an amplitude range to yield a clipped signal and clipped information, where the clipped information represents intermodulation products. The clipped information is filtered to yield an error signal. The error signal represents a subset of the intermodulation products, where an intermodulation product of the subset corresponds to the unacceptable frequency range. The error signal is subtracted from the input signal to yield an output signal. |
| FILED | Thursday, February 23, 2006 |
| APPL NO | 11/361641 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/91 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664604 | Heine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | John J. Heine (New Port Richey, Florida); Robert P. Velthuizen (Livingston, New Jersey); Jerry Alan Thomas (Potomac, Maryland) |
| ABSTRACT | The present invention is a method of determining breast cancer risk including the steps of establishing a risk probably value associated with a patient, the risk probability value calculated from an array of risk factors associated with breast cancer, applying a computer algorithm adapted to find abnormalities in the patient's mammogram, and increasing the tolerance level for false positive results in the computer algorithm responsive to a higher probability value associated with the patient and decreasing the tolerance level for false positive results in the computer algorithm responsive to a lower probability value associated with the patient. |
| FILED | Monday, December 02, 2002 |
| APPL NO | 10/065929 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07665089 | Vengerov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | David Vengerov (Sunnyvale, California) |
| ABSTRACT | One embodiment of the present invention provides a system that performs thread migration within an array of computing nodes, wherein computing nodes in the array contain central processing units (CPUs) and/or memories. During operation, the system identifies CPUs within the array of computing nodes that are available to accept a given thread. For each available CPU, the system computes an average communication distance between the CPU and memories which are accessed by the given thread. Next, the system determines whether to move the given thread to an available CPU based on the average communication distance for the available CPU. |
| FILED | Tuesday, November 02, 2004 |
| APPL NO | 10/980422 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/102 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07665092 | Vengerov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | David Vengerov (Sunnyvale, California) |
| ABSTRACT | One embodiment of the present invention provides a system that performs load balancing between task queues in a multiprocessor system. During operation, the system conditionally requests load information from a number of neighboring CPUs in a neighborhood of a requesting CPU. In response to the request, the system receives load information from one or more neighboring CPUs. Next, the system conditionally requests one or more neighboring CPUs to transfer tasks to the requesting CPU based on the received load information, thereby balancing load between the CPUs in the neighborhood. |
| FILED | Wednesday, December 15, 2004 |
| APPL NO | 11/013498 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D610038 | Kiel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Thomas J. Kiel (Bernardsville, New Jersey); Edward Zuckerman (Denville, New Jersey); Sanjay Parimi (Chester, New Jersey) |
| ABSTRACT | |
| FILED | Thursday, July 16, 2009 |
| APPL NO | 29/340305 |
| ART UNIT | 2914 — Design |
| CURRENT CPC | Transportation D12/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE41128 | Deshpande |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brewer Science Inc. (Rolla, Missouri) |
| INVENTOR(S) | Shreeram V. Deshpande (Ballwin, Missouri) |
| ABSTRACT | New polymers and new anti-reflective compositions containing such polymers are provided. The compositions comprise a polymer (e.g., epoxy cresol novolac resins) bonded with a chromophore (4-hydroxybenzoic acid, trimellitic anhydride). The inventive compositions can be applied to substrates (e.g., silicon wafers) to form anti-reflective coating layers having high etch rates which minimize or prevent reflection during subsequent photoresist exposure and developing. |
| FILED | Thursday, January 25, 2007 |
| APPL NO | 11/657983 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07661220 | Crandall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | David L. Crandall (Idaho Falls, Idaho); Richard W. Watson (Blackfoot, Idaho) |
| ABSTRACT | A firearm trigger assembly for use with a firearm includes a trigger mounted to a forestock of the firearm so that the trigger is movable between a rest position and a triggering position by a forwardly placed support hand of a user. An elongated trigger member operatively associated with the trigger operates a sear assembly of the firearm when the trigger is moved to the triggering position. An action release assembly operatively associated with the firearm trigger assembly and a movable assembly of the firearm prevents the trigger from being moved to the triggering position when the movable assembly is not in the locked position. |
| FILED | Thursday, September 09, 2004 |
| APPL NO | 10/939016 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/70.60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662217 | O'Brien et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Barry H. O'Brien (Idaho Falls, Idaho); Paul D. Ritter (Idaho Falls, Idaho) |
| ABSTRACT | A soil sampler includes a fluidized bed for receiving a soil sample. The fluidized bed may be in communication with a vacuum for drawing air through the fluidized bed and suspending particulate matter of the soil sample in the air. In a method of sampling, the air may be drawn across a filter, separating the particulate matter. Optionally, a baffle or a cyclone may be included within the fluidized bed for disentrainment, or dedusting, so only the finest particulate matter, including asbestos, will be trapped on the filter. The filter may be removable, and may be tested to determine the content of asbestos and other hazardous particulate matter in the soil sample. |
| FILED | Tuesday, April 03, 2007 |
| APPL NO | 11/695650 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Gas separation: Processes 095/275 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662263 | Chapman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | EUV LLC. (Santa Clara, California) |
| INVENTOR(S) | Henry N. Chapman (Livermore, California); John S. Taylor (Livermore, California) |
| ABSTRACT | A process is provided for producing near-perfect optical surfaces, for EUV and soft-x-ray optics. The method involves polishing or otherwise figuring the multilayer coating that has been deposited on an optical substrate, in order to correct for errors in the figure of the substrate and coating. A method such as ion-beam milling is used to remove material from the multilayer coating by an amount that varies in a specified way across the substrate. The phase of the EUV light that is reflected from the multilayer will be affected by the amount of multilayer material removed, but this effect will be reduced by a factor of 1−n as compared with height variations of the substrate, where n is the average refractive index of the multilayer. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/256317 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/192.340 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662298 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Evanston, Illinois); Samuel I. Stupp (Chicago, Illinois); Michael S. Arnold (Northbrook, Illinois) |
| ABSTRACT | The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media. |
| FILED | Monday, March 06, 2006 |
| APPL NO | 11/368581 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid purification or separation 210/781 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662321 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Jiusheng Guo (Centerville, Ohio); Lulu Song (Centerville, Ohio); Aruna Zhamu (Centerville, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | Disclosed are a nano-composite composition and a method of making such a composite that is composed of a matrix material and dispersed reinforcement nano-scaled graphene plates (NGPs) that are substantially aligned along at least one specified direction or axis. The method comprises: (a) providing a mixture of nano-scaled graphene plates (NGPs) and a matrix material in a fluent state; (b) extruding the mixture to form a filament wherein NGPs are aligned along a filament axis; (c) aligning a plurality of segments of the filament in a first direction, or moving the filament back and forth along a first direction and its opposite direction, to form a NGP-matrix filament preform; and (d) consolidating the preform to form the nanocomposite material. Also disclosed is a method of making a nano-composite fiber. |
| FILED | Wednesday, October 26, 2005 |
| APPL NO | 11/257508 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662545 | Nuzzo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); William R. Childs (Champaign, Illinois); Michael J. Motala (Champaign, Illinois); Keon Jae Lee (Savoy, Illinois) |
| ABSTRACT | A method of making a microstructure includes selectively activating a portion of a surface of a silicon-containing elastomer, contacting the activated portion with a substance, and bonding the activated portion and the substance, such that the activated portion of the surface and the substance in contact with the activated portion are irreversibly attached. The selective activation may be accomplished by positioning a mask on the surface of the silicon-containing elastomer, and irradiating the exposed portion with UV radiation. |
| FILED | Thursday, October 14, 2004 |
| APPL NO | 10/965279 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662759 | Tucker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Mark D. Tucker (Albuquerque, New Mexico); Kevin Irvine (Huntsville, Alabama); Paul Berger (Rome, New York); Robert Comstock (Bel Air, Maryland) |
| ABSTRACT | Decontamination formulations with an additive for enhancing mold remediation. The formulations include a solubilizing agent (e.g., a cationic surfactant), a reactive compound (e.g., hydrogen peroxide), a carbonate or bicarbonate salt, a water-soluble bleaching activator (e.g., propylene glycol diacetate or glycerol diacetate), a mold remediation enhancer containing Fe or Mn, and water. The concentration of Fe2+ or Mn2+ ions in the aqueous mixture is in the range of about 0.0001% to about 0.001%. The enhanced formulations can be delivered, for example, as a foam, spray, liquid, fog, mist, or aerosol for neutralization of chemical compounds, and for killing certain biological compounds or agents and mold spores, on contaminated surfaces and materials. |
| FILED | Friday, January 27, 2006 |
| APPL NO | 11/341920 |
| ART UNIT | 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Cleaning compositions for solid surfaces, auxiliary compositions therefor, or processes of preparing the compositions 510/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662785 | DeNardo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of California (Oakland, California); Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Sally DeNardo (El Macero, California); Gerald DeNardo (El Macero, California); Rodney Balhorn (Livermore, California) |
| ABSTRACT | This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity. |
| FILED | Wednesday, February 09, 2005 |
| APPL NO | 11/055181 |
| ART UNIT | 1614 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662993 | Alvarez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Marc A. Alvarez (Santa Fe, New Mexico); Rodolfo A. Martinez (Santa Fe, New Mexico); Clifford J. Unkefer (Los Alamos, New Mexico) |
| ABSTRACT | The present invention is directed to labeled compounds of the formulae wherein Q is selected from the group consisting of —S(═O)—, and —S(═O)2—, Z is selected from the group consisting of 1-naphthyl, substituted 1-naphthyl, 2-naphthyl, substituted 2-naphthyl, and phenyl groups with the structure wherein R1, R2, R3, R4 and R5 are each independently selected from the group consisting of hydrogen, a C1-C4 lower alkyl, a halogen, and an amino group selected from the group consisting of NH2, NHR and NRR′ where R and R′ are each independently selected from the group consisting of a C1-C4 lower alkyl, an aryl, and an alkoxy group, and X is selected from the group consisting of hydrogen, a C1-C4 lower alkyl group, and a fully-deuterated C1-C4 lower alkyl group. |
| FILED | Thursday, November 02, 2006 |
| APPL NO | 11/591828 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 562/427 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663077 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Jefferson Science Associates, LLC (Newport News, Virginia) |
| INVENTOR(S) | Michael W. Smith (Newport News, Virginia); Kevin Jordan (Newport News, Virginia) |
| ABSTRACT | An RF-induction heated side-pumped synthesis chamber for the production of carbon nanotubes. Such an apparatus, while capable of producing large volumes of carbon nanotubes, concurrently provides a simplified apparatus that allows for greatly reduced heat up and cool down times and flexible flowpaths that can be readily modified for production efficiency optimization. |
| FILED | Friday, October 27, 2006 |
| APPL NO | 11/589010 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electric heating 219/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663300 | Hack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey) |
| INVENTOR(S) | Michael Hack (Lambertville, New Jersey); Min-Hao Michael Lu (Lawrenceville, New Jersey); Michael S. Weaver (Princeton, New Jersey) |
| ABSTRACT | An organic light emitting device is provided. The device has a plurality of regions, each region having an organic emissive layer adapted to emit a different spectrum of light. The regions in combination emit light suitable for illumination purposes. The area of each region may be selected such that the device is more efficient that an otherwise equivalent device having regions of equal size. The regions may have an aspect ratio of at least about four. All parts of any given region may be driven at the same current. |
| FILED | Friday, August 16, 2002 |
| APPL NO | 10/219759 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/504 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663381 | Watkins, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth S. Watkins, Jr. (Dahlonega, Georgia); Shelby J. Morris (Hampton, Virginia); Daniel D. Masakowski (Worcester, Massachusetts); Ching Ping Wong (Duluth, Georgia); Shijian Luo (Boise, Idaho) |
| ABSTRACT | An electrical condition monitoring method utilizes measurement of electrical resistivity of a conductive composite degradation sensor to monitor environmentally induced degradation of a polymeric product such as insulated wire and cable. The degradation sensor comprises a polymeric matrix and conductive filler. The polymeric matrix may be a polymer used in the product, or it may be a polymer with degradation properties similar to that of a polymer used in the product. The method comprises a means for communicating the resistivity to a measuring instrument and a means to correlate resistivity of the degradation sensor with environmentally induced degradation of the product. |
| FILED | Wednesday, April 09, 2008 |
| APPL NO | 12/082161 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/693 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664147 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Rugents of the University of Colorado a body corporate (Denver, Colorado) |
| INVENTOR(S) | Oren Cohen (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado); Margaret M. Mumane (Boulder, Colorado) |
| ABSTRACT | Phase matching high harmonic generation (HHG) uses a single, long duration non-collinear modulating pulse intersecting the driving pulse. A femtosecond driving pulse is focused into an HHG medium (such as a noble gas) to cause high-harmonic generation (HHG), for example in the X-ray region of the spectrum, via electrons separating from and recombining with gas atoms. A non-collinear pulse intersects the driving pulse within the gas, and modulates the field seen by the electrons while separated from their atoms. The modulating pulse is low power and long duration, and its frequency and amplitude is chosen to improve HHG phase matching by increasing the areas of constructive interference between the driving pulse and the HHG, relative to the areas of destructive interference. |
| FILED | Monday, December 17, 2007 |
| APPL NO | 12/002523 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07661319 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Chang Liu (Winnetka, Illinois); Jonathan Engel (Minneapolis, Minnesota); Nannan Chen (Urbana, Illinois); Jack Chen (Fremont, California) |
| ABSTRACT | A micromachined artificial sensor comprises a support coupled to and movable with respect to a substrate. A polymer, high-aspect ratio cilia-like structure is disposed on and extends out-of-plane from the support. A strain detector is disposed with respect to the support to detect movement of the support. |
| FILED | Friday, June 01, 2007 |
| APPL NO | 11/809523 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/774 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07661468 | Schlitz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Ventiva, Inc. (Santa Clara, California) |
| INVENTOR(S) | Daniel Jon Schlitz (Lilburn, Georgia) |
| ABSTRACT | The present invention relates to cooling systems, and in particular to cooling systems providing forced convective gaseous flow. According to one aspect, a cooling system employs a heat sink in combination with an EHD pumping mechanism such as corona wind or micro-scale corona wind or by a temporally controlled ion-generation technique. A channel-array structure can be employed to embody the heat sink. The EHD pumps are located at the inlet or outlet of the heat sink channels. Many advantages are achieved by the cooling system of the invention, including that the entire system can have similar or better performance than a conventional heat sink and fan system but with one-tenth the volume and weight and can operate silently. The present invention also relates to a method of fabricating a micro-channel heat sink employing EHD gas flow. |
| FILED | Monday, January 23, 2006 |
| APPL NO | 11/338617 |
| ART UNIT | 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Heat exchange 165/121 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662298 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Evanston, Illinois); Samuel I. Stupp (Chicago, Illinois); Michael S. Arnold (Northbrook, Illinois) |
| ABSTRACT | The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media. |
| FILED | Monday, March 06, 2006 |
| APPL NO | 11/368581 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid purification or separation 210/781 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662545 | Nuzzo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); William R. Childs (Champaign, Illinois); Michael J. Motala (Champaign, Illinois); Keon Jae Lee (Savoy, Illinois) |
| ABSTRACT | A method of making a microstructure includes selectively activating a portion of a surface of a silicon-containing elastomer, contacting the activated portion with a substance, and bonding the activated portion and the substance, such that the activated portion of the surface and the substance in contact with the activated portion are irreversibly attached. The selective activation may be accomplished by positioning a mask on the surface of the silicon-containing elastomer, and irradiating the exposed portion with UV radiation. |
| FILED | Thursday, October 14, 2004 |
| APPL NO | 10/965279 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662644 | Hahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Klaus M. Hahn (San Diego, California); Alexei Toutchkine (San Diego, California); Rajeev Muthyala (Champaign, Illinois); Vadim Kraynov (San Diego, California); Steven J. Bark (San Diego, California); Dennis R. Burton (La Jolla, California); Chester Chamberlain (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides peptide synthons having protected functional groups for attachment of desired moieties (e.g. functional molecules or probes). Also provided are peptide conjugates prepared from such synthons, and synthon and conjugate preparation methods including procedures for identifying optimum probe attachment sites. Biosensors are provided having functional molecules that can locate and bind to specific biomolecules within living cells. Biosensors can detect chemical and physiological changes in those biomolecules as living cells are moving, metabolizing and reacting to its environment. Methods are included for detecting GTP activation of a Rho GTPase protein using polypeptide biosensors. When the biosensor binds GTP-activated Rho GTPase protein, an environmentally sensitive dye emits a signal of a different lifetime, intensity or wavelength than when not bound. New fluorophores whose fluorescence responds to environmental changes are also provided that have improved detection and attachment properties, and that can be used in living cells, or in vitro. |
| FILED | Monday, February 12, 2007 |
| APPL NO | 11/673909 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/546 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662652 | Zhou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Chongwu Zhou (Rowland Heights, California) |
| ABSTRACT | Indium oxide nanowires are used for determining information about different chemicals or Biologics. Chemicals are absorbed to the surface of the nanowires, and cause the semiconducting characteristics of the Nanowires to change. These changed characteristics are sensed, and used to determine either the presence of the materials and/or the concentration of the materials. The nanowires may be between 10 and 30 nm in diameter, formed using a comparable size particle of catalyst material. The nanowires may then be used as part of the channel of a field effect transistor, and the field effect transistor is itself characterized. |
| FILED | Tuesday, July 01, 2008 |
| APPL NO | 12/166302 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07662954 — Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
| US 07662954 | James et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Susan P. James (Bellvue, Colorado); Min Zhang (Fort Collins, Colorado); Guy Beauregard (Keokuk, Iowa) |
| ABSTRACT | An outer layer having an entanglement comprising an intermingling of cloaked hydrophilic guest and a hydrophobic polymer host, wherein molecules of the guest have been crosslinked with each other. Under certain circumstances, using complexes of the guest may be desirable or even necessary. The intermingling of the guest and host includes a physical tangling, whether it also comprises crosslinking by primary bonding (e.g., chemical/covalent bonding) there-between. Also a method of producing an outer layer having such an entanglement, including the steps of: temporarily cloaking at least a portion of the hydrophilic groups of the guest; intermingling at least a portion of the cloaked groups with a porous polymeric structure by diffusing the guest with cloaked groups into at least a portion of the structure's pores; within the pores, crosslinking at least a portion of the molecules of the guest with the guest; and removing the cloaking. Cloaking may be performed by silylation or acylation. Intermingling may be performed by producing a mixture of guest and host (whether in solution, powdered, granular, etc., form); next, a crosslinking of the guest with itself is performed; then, the mixture is molded into the outer layer. |
| FILED | Tuesday, October 29, 2002 |
| APPL NO | 10/283760 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/55.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662969 | Doyle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Michael P. Doyle (Glenn Dale, Maryland) |
| ABSTRACT | This invention relates to compositions and methods for achieving the efficient aziridination of organic molecules, especially olefins. More specifically, the invention is directed to a mild, selective, and efficient aziridination protocol that involves catalysis by a mixed-valent dirhodium(II,III) catalyst (Rh25+). Especially preferred sources for forming such mixed-valent dirhodium(II,III) catalyst (Rh25+) are dirhodium(II) carboxamidates, such as dirhodium(II) caprolactamate, and their derivatives and analogues. |
| FILED | Wednesday, March 15, 2006 |
| APPL NO | 11/375020 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663640 | Nayar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Shree Nayar (New York, New York); Michael Grossberg (New York, New York); Harish Peri (New York, New York); Peter Belhumeur (New York, New York) |
| ABSTRACT | Methods and systems are provided for displaying images onto an arbitrary surface, using a projector, such that the quality of the images is preserved despite surface imperfections or color variations. Methods and systems are also provided for controlling the appearance of a projection surface. Various embodiments use a detailed radiometric model and a calibration method to determine the pixel values required to be projected by a projector in order for a camera to observe a desired image. Other embodiments use a compensation algorithm that uses a feedback approach to provide the desired image compensation. Geometric mapping may be used to establish a correspondence between points in the images to be displayed by the projector and the corresponding points in the images that are captured by the camera. |
| FILED | Friday, July 02, 2004 |
| APPL NO | 10/883861 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/589 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664147 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rugents of the University of Colorado a body corporate (Denver, Colorado) |
| INVENTOR(S) | Oren Cohen (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado); Margaret M. Mumane (Boulder, Colorado) |
| ABSTRACT | Phase matching high harmonic generation (HHG) uses a single, long duration non-collinear modulating pulse intersecting the driving pulse. A femtosecond driving pulse is focused into an HHG medium (such as a noble gas) to cause high-harmonic generation (HHG), for example in the X-ray region of the spectrum, via electrons separating from and recombining with gas atoms. A non-collinear pulse intersects the driving pulse within the gas, and modulates the field seen by the electrons while separated from their atoms. The modulating pulse is low power and long duration, and its frequency and amplitude is chosen to improve HHG phase matching by increasing the areas of constructive interference between the driving pulse and the HHG, relative to the areas of destructive interference. |
| FILED | Monday, December 17, 2007 |
| APPL NO | 12/002523 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664642 | Espy-Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Carol Espy-Wilson (Washington, District of Columbia); Amit Juneja (Roxbury, Massachusetts) |
| ABSTRACT | A probabilistic framework for acoustic-phonetic automatic speech recognition organizes a set of phonetic features into a hierarchy consisting of a broad manner feature sub-hierarchy and a fine phonetic feature sub-hierarchy. Each phonetic feature of said hierarchy corresponds to a set of acoustic correlates and each broad manner feature of said broad manner feature sub-hierarchy is further associated with a corresponding set of acoustic landmarks. A pattern recognizer is trained from a knowledge base of phonetic features and corresponding acoustic correlates. Acoustic correlates are extracted from a speech signal and are presented to the pattern recognizer. Acoustic landmarks are identified and located from broad manner classes classified by the pattern recognizer. Fine phonetic features are determined by the pattern recognizer at and around the acoustic landmarks. The determination of fine phonetic features may be constrained by a pronunciation model. The most probable feature bundles corresponding to words and sentences are those that maximize the joint a posteriori probability of the fine phonetic features and corresponding acoustic landmarks. When the hierarchy is organized as a binary tree, binary classifiers such as Support Vector Machines can be used in the pattern classifier and the outputs thereof can be converted probability measures which, in turn may be used in the computation of the aforementioned joint probability of fine phonetic features and corresponding landmarks. |
| FILED | Thursday, March 17, 2005 |
| APPL NO | 11/081507 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/254 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07661319 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Chang Liu (Winnetka, Illinois); Jonathan Engel (Minneapolis, Minnesota); Nannan Chen (Urbana, Illinois); Jack Chen (Fremont, California) |
| ABSTRACT | A micromachined artificial sensor comprises a support coupled to and movable with respect to a substrate. A polymer, high-aspect ratio cilia-like structure is disposed on and extends out-of-plane from the support. A strain detector is disposed with respect to the support to detect movement of the support. |
| FILED | Friday, June 01, 2007 |
| APPL NO | 11/809523 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/774 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662459 | Zell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| INVENTOR(S) | Peter T. Zell (Moss Beach, California) |
| ABSTRACT | A thermal protection system for atmospheric entry of a vehicle, the system including a honeycomb structure with selected cross sectional shapes that receives and holds thermally cured thermal protection (TP) blocks that have corresponding cross sectional shapes. Material composition for TP blocks in different locations can be varied to account for different atmospheric heating characteristics at the different locations. TP block side walls may be attached to all, or to less than all, the corresponding honeycomb structure side walls. |
| FILED | Thursday, July 17, 2008 |
| APPL NO | 12/175379 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662772 | Marchionni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Acorda Therapeutics, Inc. (Hawthorne, New York); Beth Israel Deaconess Medical Center (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mark Marchionni (Arlington, Massachusetts); Ralph Kelly (Chestnut Hill, Massachusetts); Beverly Lorell (Needham, Massachusetts); Douglas B. Sawyer (Brookline, Massachusetts) |
| ABSTRACT | The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene. |
| FILED | Friday, August 22, 2003 |
| APPL NO | 10/646268 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07662114 | Seip et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Focus Surgery, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Ralf Seip (Indianapolis, Indiana); Wo-Hsing Chen (Fishers, Indiana); Narendra T. Sanghvi (Indianapolis, Indiana) |
| ABSTRACT | Ultrasound transducers are disclosed which focus acoustic energy at various focal locations while minimizing focal spot degradation and the generation of unwanted on-axis or off-axis energy concentrations through using a generally constant f-number at the various focal locations. |
| FILED | Wednesday, March 02, 2005 |
| APPL NO | 11/070371 |
| ART UNIT | 3768 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery: Kinesitherapy 61/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662321 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Jiusheng Guo (Centerville, Ohio); Lulu Song (Centerville, Ohio); Aruna Zhamu (Centerville, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | Disclosed are a nano-composite composition and a method of making such a composite that is composed of a matrix material and dispersed reinforcement nano-scaled graphene plates (NGPs) that are substantially aligned along at least one specified direction or axis. The method comprises: (a) providing a mixture of nano-scaled graphene plates (NGPs) and a matrix material in a fluent state; (b) extruding the mixture to form a filament wherein NGPs are aligned along a filament axis; (c) aligning a plurality of segments of the filament in a first direction, or moving the filament back and forth along a first direction and its opposite direction, to form a NGP-matrix filament preform; and (d) consolidating the preform to form the nanocomposite material. Also disclosed is a method of making a nano-composite fiber. |
| FILED | Wednesday, October 26, 2005 |
| APPL NO | 11/257508 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07662594 | Kong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | New England Biolabs, Inc. (Ipswich, Massachusetts) |
| INVENTOR(S) | Huimin Kong (Wenham, Massachusetts); Myriam Vincent (Crenans, France); Yan Xu (Hamilton, Massachusetts) |
| ABSTRACT | Methods and a kit are provided for selectively and exponentially amplifying nucleic acids and include the use of a single strand helicase preparation or a thermostable helicase in the absence of a single strand binding protein and a DNA polymerase such that the amplification can be performed isothermally. |
| FILED | Thursday, January 05, 2006 |
| APPL NO | 11/327175 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07664653 | Dearing |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Stephen M. Dearing (Cordova, Tennessee) |
| ABSTRACT | Systems and methods for correcting addresses to contain a code representing a delivery segment (ZIP+4™ code) within a defined geographic location (ZIP Code™) include determining whether the address is already matched with a ZIP+4™ code and contains a valid delivery point. Further, if a match the address cannot be made, the systems and method may correct or adjust the address and check if a match can be made after correcting and/or adjusting the address. If no match can be made after correcting and/or adjusting, the systems and methods may send the address to a district office and/or delivery unit to determine the ZIP+4™ code and the delivery point. |
| FILED | Monday, August 29, 2005 |
| APPL NO | 11/212808 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07664731 | Snapp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Robert F. Snapp (Memphis, Tennessee); David J. Payne (Collierville, Tennessee); James D. Wilson (Collierville, Tennessee) |
| ABSTRACT | A method and system for storing and retrieving data using hash-accessed multiple data stores, provides data protection while requiring low computational overhead and further provides storage and retrieval access based on only a single piece of access information, which is generally public. The algorithms provide high security against data-mining and other examination of the data stores. The access information is hashed and is split into offset fields used as indices into a plurality of data stores, generating a quasi-random relationship between the access information and the location of portions of a stored data element. Further protection may be provided by striping the data across the data stores in conformity with a striping order selected by a field of the hashed access information. |
| FILED | Thursday, September 22, 2005 |
| APPL NO | 11/231989 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07662592 | Stern et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Norman J Stern (Athens, Georgia); Edward A Svetoch (Serpukhov District, Russian Federation); Boris V Eruslanov (Serpukhov District, Russian Federation); Vladimir V Perelygin (Serpukhov District, Russian Federation); Vladimir P Levchuk (Serpukhov District, Russian Federation) |
| ABSTRACT | Novel peptides produced by bacteriocin-producing bacteria stimulate the production of bacteriocins in vitro. The producer bacteria are cultured in the presence of a novel inducer bacteria and a peptide having a carboxy terminal sequence of VKGLT in order to achieve an increase in bacteriocin production. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 11/782223 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/71.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07664343 | Withum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Timothy O. Withum (Olney, Maryland); Kurt P. Kopchik (Washington, District of Columbia); Oren I. Oxman (Rockville, Maryland) |
| ABSTRACT | Methods and systems of mapping of an optical character recognition (OCR) text string to a code included in a coding dictionary by supplementing the Levenshtein Distance Algorithm (LDA) with additional information in the form of adjustments based on particular character substitutions, insertions and deletions together with weighting based on multiple alternatives for the OCR text string. In one embodiment, an OCR text string mapping method (100) includes receiving (110) an OCR text string, comparing (120) it with selected text strings from a coding dictionary, computing (130) modified Levenshtein distances associated with the comparisons by determining (140) substitution penalties, determining (150) insertion penalties, determining (160) deletion penalties and combining (170) the penalties, selecting (180) the best matching text string from the coding dictionary based on the modified Levenshtein distances, determining (190) whether a maximum threshold distance is met, and assigning (200) a code associated with the best matching text string to the OCR text string when met, and assigning (210) a null or no code when not met. |
| FILED | Monday, January 23, 2006 |
| APPL NO | 11/338506 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 07663105 | Hoctor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Morpho Detection, Inc. (Newark, California) |
| INVENTOR(S) | Ralph Thomas Hoctor (Saratoga Springs, New York); Scott Stephen Zelakiewicz (Niskayuna, New York); Evren Asma (Niskayuna, New York); Jeffrey Gordon (Niskayuna, New York); Floribertus P. M. Heukensfeldt Jansen (Ballston Lake, New York) |
| ABSTRACT | An imaging system includes a platform having mounted thereon a coded-aperture imaging device and positioned to receive radiation over a baseline. The imaging system includes a computer configured to acquire a plurality of far-field datasets over the baseline, the plurality of far-field datasets comprising data received via the coded-aperture imaging device. The computer is also configured to form a preliminary image based on the acquired plurality of far-field datasets, and apply an expectation maximization (EM) algorithm to the preliminary image; wherein the EM algorithm includes an ordered subset algorithm. |
| FILED | Wednesday, December 10, 2008 |
| APPL NO | 12/331936 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/336.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 07664719 | Birdwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | John Douglas Birdwell (Oak Ridge, Tennessee); Tse-Wei Wang (Oak Ridge, Tennessee); Dale V. Stansberry (Knoxville, Tennessee); Jared Pendleton (Knoxville, Tennessee) |
| ABSTRACT | Methods of analyzing data are provided. An expert system receives input from at least a first source. Data is imported and analyzed by an expert system, wherein the expert system makes at least one first decision, which characterizes the data based on a rule base. The at least one first decision is displayable and modifiable by a first input from a first source. In response to the first input from the first source, the rule base may be re-applied to make at least one second decision, wherein the at least one second decision is different from the at least one first decision, or the at least one first decision may be accepted. The at least one first decision or the at least one second decision is then displayable and modifiable in response to a first input from a second source. In response to the first input from the second source, the rule base is either re-applied to make at least one third decision, wherein the third decision is different from the second decision, or either the first or second decisions are accepted. |
| FILED | Thursday, November 16, 2006 |
| APPL NO | 11/560601 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07662735 | Rosenflanz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | 3M Innovative Properties Company (Saint Paul, Minnesota) |
| INVENTOR(S) | Anatoly Z. Rosenflanz (Maplewood, Minnesota); Ahmet Celikkaya (Woodbury, Minnesota); Thomas J. Anderson (Woodbury, Minnesota) |
| ABSTRACT | Ceramic fibers comprising glass, and composites comprising such fibers. The glass comprises at least 35 percent by weight Al2O3, based on the total metal oxide content of the glass, a first metal oxide other than Al2O3, and a second, different metal oxide other than Al2O3. The glass contains not more than 10 percent by weight collectively As2O3, B2O3, GeO2, P2O5, SiO2, TeO2, and V2O5, based on the total weight of the glass. The first and the second metal oxides are each selected from the group consisting of Y2O3, REO, MgO, TiO2, Cr2O3, CuO, NiO, Fe2O3, ZrO2, HfO2 and complex metal oxides thereof. At least a portion of the glass may be converted to crystals. |
| FILED | Tuesday, June 26, 2007 |
| APPL NO | 11/768786 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions: Ceramic 51/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07663452 | Rauscher |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secertary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christen Rauscher (Alexandria, Virginia) |
| ABSTRACT | A ridge-waveguide filter with a signal input port at a first end and a signal output port at a second end contains a cascade assembly of metal-bounded ridge-waveguide sections with interspersed metal-bounded evanescent-mode coupling regions, and also contains low-loss ridge-waveguide port coupling networks to impedance-match the ends of the assembly to respective signal-port reference impedances. A frequency multiplexer with a composite-signal port and a plurality of channeled-signal ports is composed of a plurality of ridge-waveguide filters that are series-connected through a ridge-waveguide manifold containing a multiplicity of three-way waveguide junctions and quasi-lumped waveguide elements. |
| FILED | Wednesday, August 29, 2007 |
| APPL NO | 11/846571 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/135 |
| VIEW PATENT | @ USPTO: Full Text PDF |
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This week's information is published in the FedInvent Patents report for Tuesday, February 16, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100216.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page