FedInvent™ Patents

Patent Details for Tuesday, February 23, 2010

This page was updated on Monday, March 27, 2023 at 01:48 AM GMT

Department of Defense (DOD)

07665218 — Azimuth measuring apparatus and method

US 07665218	Pinto
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Robert P. Pinto (Dover, New Jersey)
ABSTRACT	An apparatus for measuring the azimuth of a tube having a bore axis includes a centering mandrel having a longitudinal axis; a flexible member for defining a bore axis projection of the bore axis; a tensioner fixed to one end of the flexible member, and a pair of adjusters connected to the tensioner, the adjusters for moving the tensioner along a respective pair of axes that are perpendicular to the bore axis projection, the axes of the adjusters being mutually perpendicular.
FILED	Wednesday, March 26, 2008
APPL NO	12/055533
ART UNIT	2841 — SELECT * FROM codes_techcenter;
CURRENT CPC	Geometrical instruments 033/333
VIEW PATENT	@ USPTO: Full Text PDF

07665293 — Low speed rotor shaft for a small twin spool gas turbine engine

US 07665293	Wilson, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Jack W. Wilson, Jr. (Palm Beach Gardens, Florida); Robert E. deLaneuville (North Palm Beach, Florida); Paul E. Orndoff (Palm Beach Gardens, Florida); Ryan C. McMahon (North Palm Beach, Florida)
ABSTRACT	An inner rotor shaft for use in a small twin spool gas turbine engine, the inner rotor shaft having a hollow middle section formed of a smaller diameter hollow section on a compressor end and a larger diameter hollow section on the turbine end of the shaft. Solid shaft end extend from the hollow section to form a forward solid shaft end to secure the fan rotor disk and an aft solid shaft end to secure the turbine rotor disk. A parabolic shaped transition section joins the forward shaft end to the smaller diameter hollow section, and a conical shaped transition section joins the aft shaft end to the larger diameter hollow section. A conical shaped transition piece joins the two hollow sections together to form an inner rotor shaft that can fit within a minimal space between the compressor rotor disk and the annular combustor assembly of the engine. The conical shaped transition section on the turbine end is so shaped in order to fit within a space formed inside the high pressure turbine rotor disk of the engine in order to minimize the axial spacing between the bearings that support the inner rotor shaft and raise the critical speed of the shaft to a safe level above the operating speed of the engine in order to make such a small twin spool gas turbine engine possible.
FILED	Friday, October 19, 2007
APPL NO	11/975671
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/226.100
VIEW PATENT	@ USPTO: Full Text PDF

07665300 — Thin, flexible actuator array to produce complex shapes and force distributions

US 07665300	Biggs et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	S. James Biggs (Cambridge, Massachusetts); R. Dodge Daverman (Boston, Massachusetts)
ABSTRACT	An actuator includes a bistable mechanism having a tension beam and a compression beam defined by a relief slit in a flexible substrate; and a first shape memory element that upon heating actuates the actuator from a first position to a second position. A heat source can be thermally coupled to actuate the first shape memory element, or the first shape memory element can be heated by passing current through the element. The actuators can be formed in an array. Such arrays can be useful for tactile displays, massagers, and the like. Also included are methods of operation and manufacturing.
FILED	Friday, March 11, 2005
APPL NO	11/078195
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/528
VIEW PATENT	@ USPTO: Full Text PDF

07665306 — Heat shields for use in combustors

US 07665306	Bronson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Thomas J. Bronson (Mesa, Arizona); Rodolphe Dudebout (Phoenix, Arizona)
ABSTRACT	A combustor includes an inner liner; an outer liner circumscribing the inner liner and forming a combustion chamber with the inner liner; a combustor dome coupled to the inner and outer liners; and a plurality of heat shields coupled to combustor dome. Each of the heat shields includes a heat shield plate defined by a first edge facing the inner liner and a second edge facing the outer liner; and a plurality of baffles extending from the heat shield plate. Each of the plurality of baffles includes two ribs and a connection portion connecting the two ribs to form a closed portion and an opposite open portion. The open portion of each of the plurality of baffles faces the first edge or the second edge.
FILED	Friday, June 22, 2007
APPL NO	11/767306
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/752
VIEW PATENT	@ USPTO: Full Text PDF

07665307 — Dual wall combustor liner

US 07665307	Burd et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Steven W. Burd (Cheshire, Connecticut); Stephen K. Kramer (Cromwell, Connecticut); John T. Ols (Coventry, Connecticut)
ABSTRACT	A combustor liner assembly includes an outer shell made of a ceramic composite and an inner heat shell that is supported within the outer shell. The inner heat shield defines a surface that is exposed to combustion gases. The inner heat shield is made of material that is compatible with the ceramic matrix composite and that provides favorable thermal gradient capability for a combustion chamber.
FILED	Thursday, December 22, 2005
APPL NO	11/316657
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/753
VIEW PATENT	@ USPTO: Full Text PDF

07665688 — Convertible aerial vehicle with contra-rotating wing/rotors and twin tilting wing and propeller units

US 07665688	Cylinder et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David A Cylinder (New Egypt, New Jersey); James C Kellogg (Alexandria, Virginia)
ABSTRACT	A micro aerial vehicle can be converted during flight between a fixed wing flight mode and a rotary wing flight mode. The canard design micro aerial vehicle includes a fuselage, two tiltable propellers and airfoils arranged at a forward portion of fuselage, a pair of coaxial drive shafts positioned aft of the tiltable propeller and airfoil arranged for contra-rotation, a stop rotor mechanism, and a pair of wing panels, each of the wing panels attached to one of the coaxial drive shafts. The wing panels act as contra-rotating rotor blades in the rotary wing flight mode, and act as fixed wing panels in the fixed wing mode.
FILED	Tuesday, March 27, 2007
APPL NO	11/691971
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeronautics and astronautics 244/7.A00
VIEW PATENT	@ USPTO: Full Text PDF

07665953 — Methods and system for recuperated cooling of integral turbine nozzle and shroud assemblies

US 07665953	Lee et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Ching-Pang Lee (Cincinnati, Ohio); Eric Alan Estill (Morrow, Ohio); James Harvey Laflen (Loveland, Ohio); Katherine Jaynetorrence Andersen (Cincinnati, Ohio)
ABSTRACT	A method for cooling a shroud segment of a gas turbine engine is provided. The method includes providing a turbine shroud assembly including a shroud segment having an inner surface and a leading edge that is substantially perpendicular to the inner surface, and coupling a turbine nozzle to the turbine shroud segment such that a gap is defined between an aft edge of an outer band of the turbine nozzle and the leading edge. The method also includes directing cooling air into the gap, and directing the cooling air in the gap through at least one cooling hole extending between the leading edge and the inner surface.
FILED	Thursday, November 30, 2006
APPL NO	11/565176
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Rotary kinetic fluid motors or pumps 415/1
VIEW PATENT	@ USPTO: Full Text PDF

07665959 — Rack and pinion variable vane synchronizing mechanism for inner diameter vane shroud

US 07665959	Giaimo et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	John A. Giaimo (Weston, Florida); John P. Tirone, III (Moodus, Connecticut)
ABSTRACT	An inner diameter vane shroud of a variable vane assembly accommodates a synchronization mechanism for coordinating rotation of an array of variable vanes. The inner diameter vane shroud has a gear track that runs circumferentially through the vane shroud. An array of variable vanes is rotatably mounted in the vane shroud at an inner end. Each vane has a gear pinion at its inner end, which interfaces with the gear track. As one of the individual variable vanes is rotated by an actuation source, the other variable vanes of the variable vane array are rotated a like amount by the rack and pinion gear interface.
FILED	Wednesday, July 20, 2005
APPL NO	11/185622
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Rotary kinetic fluid motors or pumps 415/160
VIEW PATENT	@ USPTO: Full Text PDF

07665960 — Turbine shroud thermal distortion control

US 07665960	Shi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Jun Shi (Glastonbury, Connecticut); Kevin E. Green (Broad Brook, Connecticut); Shaoluo L. Butler (Manchester, Connecticut); Gajawalli V. Srinivasan (South Windsor, Connecticut); Glenn N. Levasseur (Colchester, Connecticut)
ABSTRACT	A shroud suitable for use in a gas turbine engine exhibits substantially uniform thermal growth.
FILED	Thursday, August 10, 2006
APPL NO	11/502079
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Rotary kinetic fluid motors or pumps 415/173.100
VIEW PATENT	@ USPTO: Full Text PDF

07665961 — Turbine outer air seal

US 07665961	Lutjen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Paul M. Lutjen (Kennebunkport, Maine); John D. Wiedemer (Glastonbury, Connecticut); James N. Knapp (Sanford, Maine); Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Christopher R. Joe (Wethersfield, Connecticut); Blake J. Luczak (Manchester, Connecticut); Gary L. Grogg (South Berwick, Maine); Michael F. Benamati (Saco, Maine)
ABSTRACT	A turbine outer air seal includes, in a radially inner major surface thereof, at least one circumferential groove accommodating a plurality of holes which supply air for film cooling the radially inner surface of the air seal.
FILED	Wednesday, November 29, 2006
APPL NO	11/605586
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Rotary kinetic fluid motors or pumps 415/173.100
VIEW PATENT	@ USPTO: Full Text PDF

07665985 — Apparatus for distributed ignition of fuels by light sources

US 07665985	Chehroudi et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	ERC Incorporated (Huntsville, Alabama)
INVENTOR(S)	Behrouz Chehroudi (Laguna Niguel, California); Ghanshyam L. Vaghjiani (Palmdale, California); Andrew David Ketsdever (Alta Loma, California)
ABSTRACT	An apparatus for distributed ignition is disclosed wherein a combustion fuel and an ignition mixture are combined where the ignition mixture comprises ignition agents and fuel and where ignition agents can be nano-metallic particles in combination with single-walled carbon nano-tubes (SWCNTs). The combination of ignition mixture and combustion fuel in the presence of oxygen are exposed to light causing heating of the ignition agents and combustion of the fuel within which the ignition agents are interspersed. A system for igniting fuels using the method is also disclosed.
FILED	Tuesday, July 25, 2006
APPL NO	11/492728
ART UNIT	3743 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Combustion 431/2
VIEW PATENT	@ USPTO: Full Text PDF

07665999 — Land grid array (LGA) interposer structure of a moldable dielectric polymer providing for electrical contacts on opposite sides of a carrier plane

US 07665999	Hougham et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Gareth G. Hougham (Ossining, New York); Brian S. Beaman (Cary, North Carolina); Evan G. Colgan (Chestnut Ridge, New York); Paul W. Coteus (Yorktown Heights, New York); Stefano S. Oggioni (Besana in Brianza, Italy); Enrique Vargas (Bronx, New York)
ABSTRACT	A module arrangement which includes a land grid array (LGA) interposer structure, including an electrically insulating carrier plane, and at least one interposer mounted on a first surface of said carrier plane. The interposer possesses a hemi-toroidal configuration in transverse cross-section and is constituted of a moldable dielectric elastomeric material. A plurality of electrically-conductive elements are arranged about the surface of the at least one hemi-toroidal interposer and extend radically inwardly and downwardly from an uppermost end thereof into electrical contact with at least one component located on an opposite side of the electrically insulating carrier plane.
FILED	Friday, November 14, 2008
APPL NO	12/270956
ART UNIT	2839 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Electrical connectors 439/66
VIEW PATENT	@ USPTO: Full Text PDF

07666051 — Device and method for achieving enhanced field emission utilizing nanostructures grown on a conductive substrate

US 07666051	Ren et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Soldier Center (CCDC SC) Research, Development and Engineering Command (RDECOM) Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S)	Zhifeng Ren (Newton, Massachusetts); Sung Ho Jo (Chestnut Hill, Massachusetts); Debasish Banerjee (Chestnut Hill, Massachusetts)
ABSTRACT	A device and method is presented for achieving a high field emission from the application of a low electric field. More specifically, the device includes a substrate wherein a plurality of nanostructures are grown on the substrate. The relationship of the nanostructures and the substrate (the relationship includes the number of nanostructures on the substrate, the orientation of the nanostructures in relationship to each other and in relationship to the substrate, the geometry of the substrate, the morphology of the nanostructures and the morphology of the substrate, the manner in which nanostructures are grown on the substrate, the composition of nanostructure and composition of substrate, etc) allow for the generation of the high field emission from the application of the low electric field.
FILED	Tuesday, January 09, 2007
APPL NO	11/651267
ART UNIT	2889 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Electric lamp or space discharge component or device manufacturing 445/49
VIEW PATENT	@ USPTO: Full Text PDF

07666155 — Systems and methods for off-weighting a limb

US 07666155	Jensen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Medefficiency, Inc. (Wheat Ridge, Colorado)
INVENTOR(S)	Jeffrey Jensen (Evergreen, Colorado); William O. Reid, Jr. (Longmont, Colorado)
ABSTRACT	Embodiments of the present invention provide a system for limb off-weighting, including a sleeve operable to wrap at least partially around a leg, a support strut coupled to the sleeve to receive weight applied to the sleeve, and a foot assembly configured to support and protect the bottom of a foot, wherein the foot assembly is coupled to the support strut and operable to receive weight applied to the sleeve and transfer the weight to underlying surfaces, thus off-weighting and reducing pressure and shearing forces on the foot and ankle. According to some embodiments, foot assembly pivots around the support strut providing an assembled mode and a storage mode. According to other embodiments, sleeve is an open-ended conical shape. According to various other embodiments, the support strut may be tilted to accommodate legs and/or calves of varying sizes, and the foot assembly may adjust to feet of varying sizes.
FILED	Wednesday, March 16, 2005
APPL NO	11/082388
ART UNIT	3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Surgery: Splint, brace, or bandage 62/23
VIEW PATENT	@ USPTO: Full Text PDF

07666386 — Solid chemical hydride dispenser for generating hydrogen gas

US 07666386	Withers-Kirby et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Lynntech Power Systems, Ltd. (College Station, Texas)
INVENTOR(S)	Sandra Withers-Kirby (College Station, Texas); John R. Lund, Jr. (College Station, Texas); Brad Fiebig (Bryan, Texas)
ABSTRACT	A device for generating hydrogen gas is provided. The device (101) comprises a first hydrogen-containing composition (107) that reacts with a second composition to evolve hydrogen gas; a dispenser (105) adapted to apply the first composition to a first porous member (109); and a conduit (111) adapted to supply the second composition to the first porous member. In a preferred embodiment, the first composition is selected from the group consisting of hydrides, borohydrides and boranes, the second composition is water, and the dispenser is spring-loaded and is charged with the first composition. As the first composition reacts with water at the interface to evolve hydrogen gas, the dispenser forces the reaction product across the interface and out of the dispenser, where it will not interfere with the progress of the hydrogen evolution reaction.
FILED	Monday, February 06, 2006
APPL NO	11/348282
ART UNIT	1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry of inorganic compounds 423/650
VIEW PATENT	@ USPTO: Full Text PDF

07666404 — Glanders/meliodosis vaccines

US 07666404	Ulrich et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Ricky Ulrich (Hagerstown, Maryland); Jeffrey Jeddeloh (Oakville, Missouri); Petra Oyston (Salisbury, United Kingdom)
ABSTRACT	The present invention relates to nucleic acids encoding B. mallei and B. pseudomallei AHL synthases and LuxR transcriptional regulators, and methods for use, as well as describes the construction, characterization and use of avirulent strains of B. mallei and methods of use.
FILED	Tuesday, July 15, 2003
APPL NO	10/620242
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/93.200
VIEW PATENT	@ USPTO: Full Text PDF

07666414 — Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen

US 07666414	Bander
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S)	Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S)	Neil Bander (Chappaqua, New York)
ABSTRACT	Modified antibodies, or antigen-binding fragments thereof, to the extracellular domain of human prostate specific membrane antigen (PSMA) are provided. The modified anti-PSMA antibodies, or antigen-binding fragments thereof, have been rendered less immunogenic compared to their unmodified counterparts to a given species, e.g., a human. Pharmaceutical compositions including the aforesaid antibodies, nucleic acids, recombinant expression vectors and host cells for making such antibodies and fragments are also disclosed. Methods of using the antibodies of the invention to detect human PSMA, or to ablate or kill a PSMA-expressing cell, e.g., a PSMA-expressing cancer or prostatic cell, either in vitro or in vivo, are also provided.
FILED	Friday, September 02, 2005
APPL NO	11/219563
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/133.100
VIEW PATENT	@ USPTO: Full Text PDF

07666431 — Compositions and methods for the inhibition of membrane fusion by paramyxoviruses

US 07666431	Broder et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
INVENTOR(S)	Christopher C. Broder (Rockville, Maryland); Katharine N. Bossart (San Francisco, California)
ABSTRACT	Fusion of the membrane of enveloped viruses with the plasma membrane of a receptive host cell is a prerequisite for viral entry and infection and an essential step in the life cycle of all enveloped viruses, such as paramyxoviruses. The instant invention is directed to providing polypeptides which are a heptad portion of a Henipavirus F protein effective against fusion between a membrane of a paramyxovirus and a plasma membrane of a cell. The instant invention also provides nucleic acids, compositions, and methods effective against paramyxovirus infection. Accordingly, the instant invention provides therapeutic agents and vaccines effective against paramyxoviruses viruses, especially HeV or NiV.
FILED	Wednesday, November 13, 2002
APPL NO	10/528800
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/186.100
VIEW PATENT	@ USPTO: Full Text PDF

07666467 — Magnetic tunnel junctions using amorphous materials as reference and free layers

US 07666467	Parkin
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Stuart Stephen Papworth Parkin (San Jose, California)
ABSTRACT	Magnetic tunnel junctions are constructed from a MgO or Mg—ZnO tunnel barrier and amorphous magnetic layers in proximity with, and on respective sides of, the tunnel barrier. The amorphous magnetic layer preferably includes Co and at least one additional element selected to make the layer amorphous, such as boron. Magnetic tunnel junctions formed from the amorphous magnetic layers and the tunnel barrier have tunneling magnetoresistance values of up to 200% or more.
FILED	Tuesday, October 30, 2007
APPL NO	11/928602
ART UNIT	1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Coating processes 427/131
VIEW PATENT	@ USPTO: Full Text PDF

07666485 — Alkali metal-wax micropackets for alkali metal handling

US 07666485	Lal et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Amit Lal (Ithaca, New York); Shankar Radhakrishnan (Ithaca, New York)
ABSTRACT	A method of making alkali-metal vapor cells by first forming microscale-wax micropackets with alkali metals inside allows fabrication of vapor cells at low cost and in a batch fabricated manner. Alkali metals are enclosed in a chemically inert wax to preform alkali metal-wax micropackets, keeping the alkali metals from reacting with the ambient surroundings during the vapor cell fabrication. This enables the deposition of precise amounts of pure alkali metal inside the vapor cells. Laser ablation of the alkali metal-wax micropackets provides a simple and effective way of releasing the enclosed metal. The method reduces the cost of making chip-scale atomic clocks and allows shipping of alkali vapor packets without contamination issues, thereby creating a technology for alkali-metal vendors to provide small packets of alkali metals.
FILED	Tuesday, June 06, 2006
APPL NO	11/447201
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Stock material or miscellaneous articles 428/34.100
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07666588 — Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy

US 07666588	Ecker et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S)	Ibis Biosciences, Inc. (Carlsbad, California)
INVENTOR(S)	David J. Ecker (Encinitas, California); Richard H. Griffey (Vista, California); Rangarajan Sampath (San Diego, California); Steven A. Hofstadler (Oceanside, California); John McNeil (La Jolla, California); Stanley T. Crooke (Carlsbad, California); Lawrence B. Blyn (Mission Viejo, California); Thomas A. Hall (Oceanside, California); Yun Jiang (Carlsbad, California); James C. Hannis (Vista, California); Neil White (Encinitas, California); Vivek Samant (Encinitas, California); Mark W. Eshoo (Solana Beach, California); Jared J. Drader (Carlsbad, California)
ABSTRACT	The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.
FILED	Friday, September 12, 2003
APPL NO	10/660998
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
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07666592 — Methods for concurrent identification and quantification of an unknown bioagent

US 07666592	Ecker et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Ibis Biosciences, Inc. (Carlsbad, California)
INVENTOR(S)	David J. Ecker (Encinitas, California); Rangarajan Sampath (San Diego, California); Lawrence B. Blyn (Mission Viejo, California); Steven A. Hofstadler (Oceanside, California); Thomas A. Hall (Oceanside, California)
ABSTRACT	The present invention provides methods for the quantification of an unknown bioagent in a sample by amplification of nucleic acid of the bioagent, and concurrent amplification of a known quantity of a calibration polynucleotide from which are obtained a bioagent identifying amplicon and a calibration amplicon. Upon molecular mass analysis, mass and abundance data are obtained. The identity of the bioagent is then determined from the molecular mass of the bioagent identifying amplicon and the quantity of the identified bioagent in the sample is determined from the abundance data of the bioagent identifying amplicon and the abundance data of the calibration amplicon.
FILED	Thursday, February 17, 2005
APPL NO	11/059776
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
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07666594 — Methods for assaying a sample for an aggregant

US 07666594	Bazan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Singapore, Singapore)
ABSTRACT	This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.
FILED	Tuesday, January 31, 2006
APPL NO	11/344942
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666595 — Biomarkers for predicting prostate cancer progression

US 07666595	Rubin et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Materiel Command (AMC)
APPLICANT(S)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Mark A. Rubin (Cambridge, Massachusetts); Francesca Demichelis (Cambridge, Massachusetts)
ABSTRACT	The present invention relates to the identification and use of gene expression profiles with clinical relevance to prostate cancer. In particular, the invention provides the identity of genes whose expression, at the transcriptional and protein levels, is correlated with prostate cancer progression. Methods and kits are described for using these gene expression profiles in the study and/or diagnosis of prostate cancer diseases, in the prediction of prostate cancer progression, and in the selection and/or monitoring of treatment regimens. The invention also relates to the screening of drugs that target these genes or their protein products, in particular for the development of therapeutics for modulating prostate cancer progression.
FILED	Friday, February 24, 2006
APPL NO	11/361517
ART UNIT	1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666617 — Devices and methods for profiling enzyme substrates

US 07666617	Bieberich et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S)	University of Maryland, Baltimore County (Baltimore, Maryland)
INVENTOR(S)	Charles Bieberich (Brookeville, Maryland); Xiang Li (Baltimore, Maryland)
ABSTRACT	The present invention relates to apparatus and methods for separating and detecting enzyme substrates using separation gels. For example, the apparatus and methods can be used to separate and detect kinase substrates for further analysis. The apparatus and methods can also be used to detect enzyme inhibitors, such as kinase inhibitors.
FILED	Thursday, March 27, 2008
APPL NO	12/078157
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/17
VIEW PATENT	@ USPTO: Full Text PDF

07666684 — Determination of explosives including RDX

US 07666684	Swager et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Timothy M. Swager (Newton, Massachusetts); Trisha L. Andrew (Cambridge, Massachusetts); Samuel W. Thomas (Quincy, Massachusetts); Jean Bouffard (Cambridge, Massachusetts)
ABSTRACT	The present invention provides sensors and methods for determination of an analyte. The analytes may be determined by monitoring, for example, a change in an optical signal of an emissive material upon exposure to an analyte. In some embodiments, the analyte and the emissive material may interact via a chemical reaction, or other chemical, biochemical or biological interaction (e.g., recognition), to form a new emissive species. In some cases, the present invention may be used for the detection of analytes such as explosives (e.g., RDX, PETN). Methods of the present invention may be advantageous in that the high sensitivity of luminescence (e.g., fluorescence) spectroscopy can allow for the reliable detection of small changes in luminescence intensity.
FILED	Monday, October 16, 2006
APPL NO	11/581777
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry: Analytical and immunological testing 436/106
VIEW PATENT	@ USPTO: Full Text PDF

07666708 — Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices

US 07666708	Lieber et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Charles M. Lieber (Lexington, Massachusetts); Yi Cui (Union City, California); Xiangfeng Duan (Mountain View, California); Yu Huang (Cambridge, Massachusetts)
ABSTRACT	A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal is, axis, has a largest cross-sectional dimension less than 500 nanometers, and a free-standing and bulk-doped semiconductor with at least one portion having a smallest width of less than 500 nanometers. At least one portion of such a semiconductor may a smallest width of less than 200 nanometers, or less than 150 nanometers, or less than 100 nanometers, or less than 80 nanometers, or less than 70 nanometers, or less than 60 nanometers, or less than 40 nanometers, or less than 20 nanometers, or less than 10 nanometers, or even less an 5 nanometers. Such a semiconductor may be doped during growth. Such a semiconductor may be part of a device, which may include any of a variety of devices and combinations thereof, and a variety assembling techniques may be used to fabricate devices from such a semiconductor.
FILED	Wednesday, October 04, 2006
APPL NO	11/543352
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/99
VIEW PATENT	@ USPTO: Full Text PDF

07666911 — Self assembled nanostructures and methods for preparing the same

US 07666911	Russell et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Multidisciplinary University Research Initiative (MURI)
APPLICANT(S)
ASSIGNEE(S)	NanoSembly, LLC (Harrison City, Pennsylvania)
INVENTOR(S)	Alan J. Russell (Gibsonia, Pennsylvania); Richard R. Koepsel (Pittsburgh, Pennsylvania); Sang Beom Lee (Harrison City, Pennsylvania)
ABSTRACT	The present invention provides amphiphilic diacetylene compounds, and compositions and self-assembled nanotubes containing the same. Also provided are methods of producing the compounds, compositions, and nanotubes of the invention, and methods of destroying or inhibiting the growth or proliferation of microorganisms using the nanotubes of the present invention.
FILED	Tuesday, September 27, 2005
APPL NO	11/237838
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/614
VIEW PATENT	@ USPTO: Full Text PDF

07666981 — Inhibitors of prostasin

US 07666981	Chai et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Karl X. Chai (Winter Springs, Florida); Li-Mei Chen (Winter Springs, Florida)
ABSTRACT	A class of proteins useful as inhibitors of prostasin and method for identifying them are provided. These proteins have the structure wherein the amino acids P1-P4 from the scissile bond are respectively leu-ile-ala-arg and the amino acids at positions P5-P15 are serpin sequences.
FILED	Thursday, May 08, 2003
APPL NO	10/434349
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324
VIEW PATENT	@ USPTO: Full Text PDF

07667012 — Chemoselective ligation

US 07667012	Saxon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Eliana Saxon (Albany, California); Carolyn R. Bertozzi (Berkeley, California)
ABSTRACT	The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g. on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
FILED	Thursday, April 20, 2006
APPL NO	11/408605
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Organic compounds 536/17.200
VIEW PATENT	@ USPTO: Full Text PDF

07667046 — N-sulfonyldicarboximide containing tethering compounds

US 07667046	Benson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S)	Karl E. Benson (St. Paul, Minnesota); Moses M. David (Woodbury, Minnesota); Cary A. Kipke (Woodbury, Minnesota); Brinda B. Lakshmi (Woodbury, Minnesota); Charles M. Leir (Falcon Heights, Minnesota); George G. Moore (Afton, Minnesota); Rahul Shah (Woodbury, Minnesota)
ABSTRACT	Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonyldicarboximide group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a connector group between the substrate and the amine-containing material. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.
FILED	Monday, November 19, 2007
APPL NO	11/942060
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Organic compounds 548/435
VIEW PATENT	@ USPTO: Full Text PDF

07667399 — Large area hybrid photomultiplier tube

US 07667399	Contarino et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Vincent Michael Contarino (Lusby, Maryland); Pavlo Molchanov (Lexington Park, Maryland)
ABSTRACT	A large area hybrid photomultiplier tube that includes a photocathode for emitting photoelectrons in correspondence with incident light, a semiconductor device having an electron incident surface for receiving photoelectrons from the photocathode, and a cone shaped container. The container has a first opening and a second opening. The photocathode is disposed at the first opening, and the semiconductor device is disposed at the second opening.
FILED	Thursday, April 26, 2007
APPL NO	11/801771
ART UNIT	2889 — Optics
CURRENT CPC	Electric lamp and discharge devices 313/532
VIEW PATENT	@ USPTO: Full Text PDF

07667467 — Method and system for determining antenna characterization

US 07667467	Khosravi et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Mahmood F. Khosravi (Bedford, New Hampshire); Robert B. Lombardi (Nashua, New Hampshire); Donald B. Spencer (Merrimack, New Hampshire); Leonard Ruvinsky (Merrimack, New Hampshire); Michael C. Freeman (Franklin, New Hampshire)
ABSTRACT	An antenna and its associated components are consolidated in a small measurement box, and multiple tests are competed simultaneously, with a single vector network analyzer. This can be done by treating the “Far Field” measurements (typically measured on antenna/RCS ranges) as another port of a larger passive network. After characterization of one ideal “gold” unit (or a sample set of “gold” units), the S-parameters of subsequent units are measured in the same passive test box environment. The results of these subsequent tests are compared to the results of the “gold unit's” test, and if they are repeated to within some tolerance, electrical similarity can be proven.
FILED	Friday, August 05, 2005
APPL NO	11/596137
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Measuring and testing 324/638
VIEW PATENT	@ USPTO: Full Text PDF

07667515 — Time delay apparatus and method of using same

US 07667515	Elliott et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Ken Elliott (Thousand Oaks, California); Susan Morton (Newbury Park, California); Mark Rodwell (Goleta, California)
ABSTRACT	Disclosed is a time delay generator 200 apparatus and method. The apparatus includes a time delay gate 212, a mixer 216 (a Gilbert cell circuit), and a current digital to analog converter 206. The mixer 216, comprised of first and second transistor differential pairs 218 and 220, receives an analog input signal 202 without a delay as well as a delayed input signal 210 produced by the time gate delay. The digital to analog converter regulates the relative current flow between a first control signal 232 and a second control signal 238, effectively altering the mixing of the undelayed input signal 208 and the delayed input signal 210 to generate a delayed output signal 214 with a time or phase delay substantially equal to the temporal delay represented by the digital signal input 204. The time delay generator exhibits reduced phase noise and a linear time delay response.
FILED	Saturday, May 31, 2008
APPL NO	12/156266
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Miscellaneous active electrical nonlinear devices, circuits, and systems 327/280
VIEW PATENT	@ USPTO: Full Text PDF

07667555 — Composite right/left handed (CRLH) branch-line couplers

US 07667555	Itoh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Multidisciplinary University Research Initiative (MURI)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Tatsuo Itoh (Rolling Hills, California); Christophe Caloz (Montreal, Canada); I-Hsiang Lin (Mountain View, California); Hiroshi Okabe (Tokyo, Japan)
ABSTRACT	High-frequency couplers and coupling techniques are described utilizing artificial composite right/left-handed transmission line (CRLH-TL). Three specific forms of couplers are described; (1) a coupled-line backward coupler is described with arbitrary tight/loose coupling and broad bandwidth; (2) a compact enhanced-bandwidth hybrid ring coupler is described with increased bandwidth and decreased size; and (3) a dual-band branch-line coupler that is not limited to a harmonic relation between the bands. These variations are preferably implemented in a microstrip fabrication process and may use lumped-element components. The couplers and coupling techniques are directed at increasing the utility while decreasing the size of high-frequency couplers, and are suitable for use with separate coupler or couplers integrated within integrated devices.
FILED	Friday, May 16, 2008
APPL NO	12/122371
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Wave transmission lines and networks 333/118
VIEW PATENT	@ USPTO: Full Text PDF

07667560 — Membrane actuator based on ferromagnetic shape memory alloy composite for synthetic jet actuator

US 07667560	Taya et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Minoru Taya (Seattle, Washington); Robert Yuanchang Liang (Seattle, Washington); Yasuo Kuga (Seattle, Washington)
ABSTRACT	A membrane actuator includes a magnetically actuatable membrane and a magnetic trigger. The membrane includes a shape memory alloy (SMA), and the magnetic trigger is configured to induce a martensitic transformation in the SMA, to produce a larger force than would be achievable with non-SMA-based materials. Such a membrane actuator can be beneficially incorporated into a wide variety of devices, including fluid pumps, shock absorbing systems, and synthetic jet producing devices for use in an aircraft. The membrane/diaphragm can be formed from a ferromagnetic SMA, or a ferromagnetic material can be coupled with an SMA such that the SMA and the ferromagnetic material move together. A hybrid magnetic trigger, including a permanent magnet and an electromagnet, is preferably used for the magnetic trigger, as hybrid magnetic triggers are easy to control, and produce larger magnetic gradients than permanent magnets or electromagnets alone.
FILED	Monday, July 09, 2007
APPL NO	11/774916
ART UNIT	2832 — Semiconductors/Memory
CURRENT CPC	Electricity: Magnetically operated switches, magnets, and electromagnets 335/78
VIEW PATENT	@ USPTO: Full Text PDF

07667830 — Mixer-based time domain reflectometer and method

US 07667830	Harres
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The Boeing Company (Irvine, California)
INVENTOR(S)	Daniel N. Harres (Belleville, Illinois)
ABSTRACT	An apparatus to measure optical characteristics of a fiber optic transmission line or other optical medium may include a source to generate a bipolar pulse signal waveform. The apparatus may also include a mixer to mix the bipolar pulse signal waveform and an optical pulse and reflected signal waveform from the fiber optic transmission line or other optical medium to form a mixed product waveform, wherein the reflected signal is responsive to the optical pulse being transmitted into the fiber optic transmission line or optical medium.
FILED	Thursday, March 23, 2006
APPL NO	11/277239
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/73.100
VIEW PATENT	@ USPTO: Full Text PDF

07667994 — Magnetic racetrack with current-controlled motion of domain walls within an undulating energy landscape

US 07667994	Moriya et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Rai Moriya (San Jose, California); Stuart Parkin (San Jose, California); Luc Thomas (San Jose, California)
ABSTRACT	A method for use with a magnetic racetrack device includes placing domain walls having a first structure and domain walls having a second, different structure along the racetrack at stable positions corresponding to different regions within the device. The domain walls having the first structure and the domain walls having the second structure occupy alternating positions along the racetrack. A current pulse is applied to the racetrack, so that each of the domain walls moves to an adjacent region. This results in a transformation of the domain walls having the first structure into domain walls having the second structure, and vice versa. The first structure may be a vortex structure and the second structure may be a transverse structure.
FILED	Wednesday, September 02, 2009
APPL NO	12/552667
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Static information storage and retrieval 365/81
VIEW PATENT	@ USPTO: Full Text PDF

07668212 — Optically triggered Q-switched photonic crystal laser and method of switching the same

US 07668212	Maune
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Brett Maune (New York, New York)
ABSTRACT	An improvement in a method of controlling lasing in a semiconductor laser fabricated in a photonic crystal laser having a plurality of holes into which a birefringent material with low refractive losses and low optical loses with controllable spatial refractive index orientation has been infiltrated comprises the step of rotating the molecular orientation or changing the physical orientation of the birefringent material infiltrated into the holes of the photonic crystal laser to switch cavity modes. The liquid crystal is aligned by use of an alignable photo addressable polymer layer adjacent to the liquid crystal. The cavity modes are optically switched within the laser without any requirement of external energy to maintain the lasing state of the laser, which allows its use as a memory element.
FILED	Monday, January 23, 2006
APPL NO	11/338495
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Coherent light generators 372/10
VIEW PATENT	@ USPTO: Full Text PDF

07668266 — Crest factor reduction in OFDM using blind selected pilot tone modulation

US 07668266	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Ning Chen (Atlanta, Georgia); Guotong Zhou (Atlanta, Georgia)
ABSTRACT	Orthogonal frequency division multiplexing (OFDM) is a spectrally efficient multicarrier modulation technique for high speed data transmission over multipath fading channels, but has low power efficiency. OFDM signals have large crest factors, or peak-to-average power ratios (PARs) which lead to power inefficiency in the RF portion of the transmitter. Selected mapping can be used to reduce the PAR of an OFDM signal and is distortionless. A technique is disclosed that links the index of a phase rotation sequence used in selected mapping to the location of pilot tones that are used to estimate the channel. Each pilot tone location-phase sequence selection produces a different PAR value for the time-domain OFDM signal, and the signal with the lowest PAR value is transmitted. The technique is “blind” in that the optimum pilot tone location-phase sequence index is not transmitted as side information. A technique to blindly detect the optimum index at the receiver is also disclosed.
FILED	Tuesday, March 14, 2006
APPL NO	11/374704
ART UNIT	2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Pulse or digital communications 375/347
VIEW PATENT	@ USPTO: Full Text PDF

07668627 — Mechanical flight control auxiliary power assist system

US 07668627	Shultz et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S)	Bell Helicopter Textron Inc. (Fort Worth, Texas)
INVENTOR(S)	Peter M. Shultz (North Richland Hills, Texas); Carlos A. Fenny (Arlington, Texas); Todd Walker (Fort Worth, Texas); Sam Arjunan (Great Mills, Maryland)
ABSTRACT	A mechanical flight control system for a rotary-wing aircraft is disclosed. The flight control system comprises an upstream portion, a downstream portion, and a booster means for connecting the upstream portion to the downstream portion. The booster means may comprise dual concentric valve actuators and/or a variety of system load limiting features.
FILED	Thursday, October 13, 2005
APPL NO	11/664664
ART UNIT	3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/3
VIEW PATENT	@ USPTO: Full Text PDF

07668664 — Design and selection of genetic targets for sequence resolved organism detection and identification

US 07668664	Malanoski et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Anthony P. Malanoski (Greenbelt, Maryland); Zheng Wang (Burke, Virginia); Baochuan Lin (Bethesda, Maryland); David A Stenger (Herndon, Virginia); Joel M Schnur (Burke, Virginia)
ABSTRACT	A computer-implemented method as follows. Providing a list of target sequences associated with one or more organisms. Providing a list of candidate prototype sequences suspected of hybridizing to one or more of the target sequences. Generating a collection of probes corresponding to each candidate prototype sequence, each collection of probes having a set of probes for every subsequence. The sets consist of the corresponding subsequence and every variation of the corresponding subsequence formed by varying a center nucleotide of the corresponding subsequence. Generating a set of fragments corresponding to each target sequence. Calculating the binding free energy of each fragment with a perfect complimentary sequence of the fragment. Determining which extended fragments are perfect matches to any of the probes. Assembling a base call sequence corresponding to each candidate prototype sequence.
FILED	Wednesday, August 22, 2007
APPL NO	11/843126
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/20
VIEW PATENT	@ USPTO: Full Text PDF

07668699 — Optimized stochastic resonance method for signal detection and image processing

US 07668699	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S)	Syracuse University (Syracuse, New York)
INVENTOR(S)	Hao Chen (Syracuse, New York); James Michels (Ithaca, New York); Pramod K Varshney (Fayetteville, New York)
ABSTRACT	Apparatus and method for improving the detection of signals obscured by noise using stochastic resonance noise. The method determines the stochastic resonance noise probability density function in non-linear processing applications that is added to the observed data for optimal detection with no increase in probability of false alarm. The present invention has radar, sonar, signal processing (audio, image and video), communications, geophysical, environmental, and biomedical applications.
FILED	Friday, October 20, 2006
APPL NO	11/551473
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/191
VIEW PATENT	@ USPTO: Full Text PDF

07668790 — System and method for fusing data from different information sources with shared-sampling distribution based boosting

US 07668790	Barbu et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Costin Barbu (Hattiesburg, Mississippi); Maura C Lohrenz (Pearl River, Louisiana)
ABSTRACT	A boosting—based method and system for fusing a set of classifiers that performs classification using weak learners trained on different views of the training data. The final ensemble contains learners that are trained on examples sampled with a shared sampling distribution. The combination weights for the final weighting rule are obtained at each iteration based on the lowest training error among the views. Weights are updated in each iteration based on the lowest training error among all views at that iteration to form the shared sampling distribution used at the next iteration. In each iteration, a weak learner is selected from the pool of weak learners trained on disjoint views based on the lowest training error among all views, resulting in a lower training and generalization error bound of the final hypothesis.
FILED	Monday, September 25, 2006
APPL NO	11/534697
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/25
VIEW PATENT	@ USPTO: Full Text PDF

07669081 — Systems and methods for scheduling, processing, and monitoring tasks

US 07669081	Lett et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Richard Lett (Fort Wayne, Indiana); Gregory Renno (Fort Wayne, Indiana); Thomas Terwiel (Fort Wayne, Indiana)
ABSTRACT	A computer-implemented method for performing a process is provided. The method comprises: (a) receiving a request to perform a process, the process comprising a plurality of tasks and at least a scheduler rule; (b) receiving a plurality of checkpoints associated with the process, each checkpoint comprising checkpoint state data and at least a respective checkpoint rule governing execution of the process; (c) determining a first task of the plurality of tasks to be scheduled into a priority queue, in accordance with the scheduler rule; (d) determining the first checkpoint of the plurality of checkpoints that is to be the first checkpoint used in processing the first task, in accordance with the scheduler rule; (e) creating the checkpoint state data for the first checkpoint; (f) saving the checkpoint state data for the first checkpoint; (g) processing the first task in accordance with the checkpoint rule associated with the first checkpoint; (h) determining the next task in the plurality of tasks to perform, based on the checkpoint rule associated with the first checkpoint; (i) updating the saved checkpoint data for the first checkpoint with the data and state associated with the first task; and (j) repeating steps (c) through (i) for each subsequent task and checkpoint, in accordance with the respective scheduler and checkpoint rules, until a predetermined condition has been reached.
FILED	Wednesday, September 27, 2006
APPL NO	11/535723
ART UNIT	2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Error detection/correction and fault detection/recovery 714/20
VIEW PATENT	@ USPTO: Full Text PDF

Department of Health and Human Services (HHS)

07666259 — Screening and crystallization plates for manual and high-throughput protein crystal growth

US 07666259	Thorne et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S)	Robert E. Thorne (Ithaca, New York); Viatcheslav Berejnov (Ithaca, New York); Yevgeniy Kalinin (Ithaca, New York)
ABSTRACT	In one embodiment, a crystallization and screening plate comprises a plurality of cells open at a top and a bottom, a frame that defines the cells in the plate, and at least two films. The first film seals a top of the plate and the second film seals a bottom of the plate. At least one of the films is patterned to strongly pin the contact lines of drops dispensed onto it, fixing their position and shape. The present invention also includes methods and other devices for manual and high-throughput protein crystal growth.
FILED	Tuesday, August 08, 2006
APPL NO	11/463033
ART UNIT	1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/68
VIEW PATENT	@ USPTO: Full Text PDF

07666284 — Electrodes with multilayer membranes and methods of using and making the electrodes

US 07666284	Heller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S)	Abbott Diabetes Care Inc. (Alameda, California)
INVENTOR(S)	Adam Heller (Austin, Texas); Ting Chen (Austin, Texas); Keith A. Friedman (Austin, Texas)
ABSTRACT	A sensor including a sensing layer is disposed over an electrode or an optode and a layer-by-layer assembled mass transport limiting membrane disposed over the sensing layer. The membrane includes at least one layer of a polyanionic or polycationic material. The assembled layers of the membrane are typically disposed in an alternating manner. The sensor also optionally includes a biocompatible membrane.
FILED	Monday, June 07, 2004
APPL NO	10/862932
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry: Electrical and wave energy 24/403.10
VIEW PATENT	@ USPTO: Full Text PDF

07666389 — Method of imaging cell death in vivo

US 07666389	Blankenberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); University of Washington (Seattle, Washington)
INVENTOR(S)	Francis G. Blankenberg (Menlo Park, California); Peter D. Katsikis (Merion Station, Pennsylvania); H. William Strauss (West Harrison, New York); Jonathan F. Tait (Seattle, Washington)
ABSTRACT	A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
FILED	Thursday, November 15, 2007
APPL NO	11/985567
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/1.110
VIEW PATENT	@ USPTO: Full Text PDF

07666391 — Breast homing peptides and methods of identifying same using aminopeptidase P

US 07666391	Ruoslahti et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Burnham Institute for Medical Research (La Jolla, California)
INVENTOR(S)	Erkki Ruoslahti (Rancho Santa Fe, California); Markus Essler (La Jolla, California)
ABSTRACT	The present invention provides a method of directing a moiety to breast vasculature in a subject by administering to the subject a conjugate which contains a moiety linked to a homing molecule that selectively homes to breast vasculature, whereby the moiety is directed to breast vasculature. In one embodiment, the homing molecule is a peptide containing the amino acid sequence PGPEGAG (SEQ ID NO: 1), or a peptidomimetic thereof.
FILED	Wednesday, May 29, 2002
APPL NO	10/158566
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.100
VIEW PATENT	@ USPTO: Full Text PDF

07666394 — Nanoparticles having reactive ester groups covalently coupled thereto and related methods

US 07666394	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Miqin Zhang (Bothell, Washington); Nathan Kohler (Seattle, Washington); Jonathan Whitney Gunn (Seattle, Washington)
ABSTRACT	A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
FILED	Wednesday, November 05, 2008
APPL NO	12/265489
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.320
VIEW PATENT	@ USPTO: Full Text PDF

07666395 — Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs

US 07666395	Boucher, Jr.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Richard C. Boucher, Jr. (Chapel Hill, North Carolina)
ABSTRACT	Chronic obstructive airway diseases are treated by administering an osmotically active compound such as a salt, sugar, sugar alcohol, or organic osmolyte to the afflicted airway surface. The compound may be administered as a liquid or dry powder aerosol formulation. Diseases that can be treated by the method include cystic fibrosis, chronic bronchitis, and ciliary dyskinesia. The formulations of the invention can also be used in conjunction with other active agents such as bronchodilators, sodium channel blockers, antibiotics, enzymes, or purinoceptor agonists on airway surfaces.
FILED	Thursday, November 18, 2004
APPL NO	10/992454
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/46
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07666405 — Deleted adenovirus vectors and methods of making and administering the same

US 07666405	Amalfitano et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Andrea Amalfitano (Durham, North Carolina); Yuan Tsong Chen (Chapel Hill, North Carolina); Huimin Hu (Memphis, Tennessee); Bradley Lowell Hodges (Milford, Massachusetts)
ABSTRACT	The present invention provides deleted adenovirus vectors. The inventive adenovirus vectors carry one or more deletions in the IVa2, 100K, polymerase and/or preterminal protein sequences of the adenovirus genome. The adenoviruses may additionally contain other deletions, mutations or other modifications as well. In particular preferred embodiments, the adenovirus genome is multiply deleted, i.e., carries two or more deletions therein. The deleted adenoviruses of the invention are “propagation-defective” in that the virus cannot replicate and produce new virions in the absence of complementing function(s). Preferred adenovirus vectors of the invention carry a heterologous nucleotide sequence encoding a protein or peptide associated with a metabolic disorder, more preferably a protein or peptide associated with a lysosomal or glycogen storage disease, most preferably, a lysosomal acid α-glucosidase. Further provided are methods for producing the inventive deleted adenovirus vectors. Further provided are methods of administering the deleted adenovirus vectors to a cell in vitro or in vivo.
FILED	Tuesday, September 07, 2004
APPL NO	10/935576
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/93.200
VIEW PATENT	@ USPTO: Full Text PDF

07666411 — Methods of treating and preventing colitis involving IL-13 and NK-T cells

US 07666411	Strober et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Warren Strober (Bethesda, Maryland); Ivan J. Fuss (Bethesda, Maryland); Frank Heller (Berlin, Germany); Richard S. Blumberg (Chestnut Hill, Massachusetts)
ABSTRACT	Method of treating or preventing the inflammatory response of colitis in a subject comprising administering to the subject an effective amount of a substance that modulates IL-13 activity (FIG. 3). The invention also provides a method of treating or preventing the inflammatory response of colitis in a subject comprising administering to the subject an effective amount of a substance that modulates NK-T cell activity. The invention also provides for the screening of substances that treat or prevent the inflammatory response of colitis.
FILED	Friday, June 14, 2002
APPL NO	10/517898
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/130.100
VIEW PATENT	@ USPTO: Full Text PDF

07666412 — Methods for the treatment of neoplastic disorders with anti-caveolin agents

US 07666412	Thompson
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Baylor College of Medicine (Houston, Texas)
INVENTOR(S)	Timothy C. Thompson (Houston, Texas)
ABSTRACT	The present invention relates to methods for the diagnosis, evaluation and treatment of metastatic diseases using metastatic sequences, such as caveolin, to target metastatic cells. According to the methods of the present invention, certain cancers, including metastatic prostate cancer, may be treated by therapies which suppress expression of the caveolin gene. The present invention relates to biological technologies designed to block the activity of caveolin or the function of caveolae, including vector delivery of antisense caveolin sequences, the use of anti-caveolin antibodies, the use of promoters, and other approaches targeting the expression of caveolin.
FILED	Wednesday, October 22, 2003
APPL NO	10/690713
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/130.100
VIEW PATENT	@ USPTO: Full Text PDF

07666417 — Methods and compositions for treating autoimmune diseases or conditions

US 07666417	Spies et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S)	Thomas Spies (Seattle, Washington); Veronika Spies (Seattle, Washington)
ABSTRACT	The present invention relates to methods of treating immune disorders, particularly autoimmune and inflammatory disorders such as rheumatoid arthritis, and methods of producing antibodies for use in therapeutic strategies for treating such disorders. Generally, the present methods involve the use of antibodies that specifically bind to NKG2D receptors present on the surface of cells underlying the disorders.
FILED	Friday, July 23, 2004
APPL NO	10/898003
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/143.100
VIEW PATENT	@ USPTO: Full Text PDF

07666424 — Methods of preparing and using single chain anti-tumor antibodies

US 07666424	Cheung et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S)	Nai-Kong Cheung (Purchase, New York); Hong-Fen Guo (New York, New York)
ABSTRACT	This invention provides a method for identifying cells expressing a target single chain antibody (scFv) directed against a target antigen from a collection of cells that includes cells that do not express the target scFv, comprising the step of combining the collection of cells with an anti-idiotype directed to an antibody specific for the target antigen and detecting interaction, if any, of the anti-idiotype with the cells, wherein the occurrence of an interaction identifies the cell as one which expresses the target scFv. This invention also provides a method for making a single chain antibody (scFv) directed against an antigen, wherein the selection of clones is made based upon interaction of those clones with an appropriate anti-idiotype, and heretofore inaccessible scFv so made. This invention provides the above methods or any combination thereof. Finally, this invention provides various uses of these methods.
FILED	Thursday, October 17, 2002
APPL NO	10/273762
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/178.100
VIEW PATENT	@ USPTO: Full Text PDF

07666427 — HIV vaccines based on Env of multiple clades of HIV

US 07666427	Nabel et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Gary J. Nabel (Washington, District of Columbia); Bimal Chakrabarti (Gaithersburg, Maryland); Wing-pui Kong (Germantown, Maryland); Yue Huang (Bethesda, Maryland); Zengguang Wang, legal representative (Silver Spring, Maryland); Zhi-yong Yang (Potomac, Maryland)
ABSTRACT	In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.
FILED	Wednesday, June 13, 2007
APPL NO	11/818113
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/184.100
VIEW PATENT	@ USPTO: Full Text PDF

07666430 — Polypeptides and polynucleotides for enhancing immune reactivity to HER-2 protein

US 07666430	Kaumaya
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S)	The Ohio State University (Columbus, Ohio)
INVENTOR(S)	Pravin T. P. Kaumaya (Westerville, Ohio)
ABSTRACT	Compositions for stimulating the immune system and for treating malignancies associated with overexpression of the HER-2 protein are provided. Such compositions include immunogenic epitopes of the HER-2 proteins and chimeric and multivalent peptides which comprise such epitopes. The present invention also relates to polynucleotides which encode the chimeric peptides. Also provided are pharmaceutical compositions comprising such immunogenic compositions. Methods for stimulating an immune response to HER-2 protein are provided. Methods for treating breast cancer, ovarian cancer, prostate cancer, colon cancer and lung cancer are provided.
FILED	Friday, June 09, 2006
APPL NO	11/423194
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/185.100
VIEW PATENT	@ USPTO: Full Text PDF

07666434 — Rapid, efficient purification of HSV-specific T-lymphocytes and HSV antigens identified via same

US 07666434	Koelle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	David M. Koelle (Seattle, Washington); Zhi Liu (Seattle, Washington); Lawrence Corey (Mercer Island, Washington)
ABSTRACT	Described is a method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are specific to a virus that attacks skin. Also provided are HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection that have been identified via the methods of the invention. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection.
FILED	Thursday, September 18, 2008
APPL NO	12/233280
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/229.100
VIEW PATENT	@ USPTO: Full Text PDF

07666523 — Electrode surface coating and method for manufacturing the same

US 07666523	Zhou
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)	Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S)	Dao Min Zhou (Saugus, California)
ABSTRACT	An electrode surface coating and method for manufacturing the electrode surface coating comprising a conductive substrate; and one or more surface coatings comprising one or more of the following metals titanium, niobium, tantalum, ruthenium, rhodium, iridium, palladium, or gold, or an alloy of two or more metals, or a combination of two or more alloys or metal layers thereof having an increase in the surface area of 5 times to 500 times of the corresponding surface area resulting from the basic geometric shape.
FILED	Thursday, August 17, 2006
APPL NO	11/506290
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Stock material or miscellaneous articles 428/670
VIEW PATENT	@ USPTO: Full Text PDF

07666581 — Methods for preparing compositions comprising heat shock proteins useful for the treatment of cancer and infectious disease

US 07666581	Srivastava
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Connecticut Health Center (Farmington, Connecticut)
INVENTOR(S)	Pramod K. Srivastava (Avon, Connecticut)
ABSTRACT	The present invention relates to methods and compositions for the prevention and treatment of infectious diseases, and cancers. The methods of the invention comprises complexing a population of antigenic proteins or antigenic peptides derived from antigenic cells or viral particles to one or more different heat shock proteins in vitro. The population or the protein preparation used to produce the antigenic peptides comprises at least 50% of the different proteins or at least 50 different proteins of the antigenic cells or viral particles. Methods for making antigenic peptides comprise digesting a protein preparation of antigenic cells, a cellular fraction thereof, or of viral particles with one or more proteases, or exposing the protein preparation to ATP, guanidium hydrochloride, and/or acidic conditions.
FILED	Tuesday, August 20, 2002
APPL NO	10/225367
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

07666584 — Identification of a pin specific gene and protein (PIN-1) useful as a diagnostic treatment for prostate cancer

US 07666584	Stearns et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Philadelphia Health and Education Coporation (Philadelphia, Pennsylvania)
INVENTOR(S)	Mark E. Stearns (Villanova, Pennsylvania); Youji Hu (Gulph Mills, Pennsylvania); Min Wang (Gulph Mills, Pennsylvania)
ABSTRACT	The invention relates to nucleic acids encoding a mammalian ABCA5 gene, and proteins encoded thereby, whose expression is increased in certain diseases, disorders, or conditions, including, but not limited to, PIN. Further, the invention relates to diagnostic assays for identifying the DNA-binding protein ABCA5 (also known as PIN-1). The invention also relates to oligonucleotide sequence(s) or antibodies that specifically bind with ABCA5 or variants thereof.
FILED	Friday, September 01, 2006
APPL NO	11/515475
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

07666587 — Method of screening test substances for treating or preventing a disease mediated by plasma cells

US 07666587	Ron et al.
FUNDED BY	Department of Health and Human Services (HHS) U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	David Ron (New York, New York); Marcella Calfon (New York, New York); Heather Harding (Brooklyn, New York); Yuhong Zhang (Elmhurst, New York)
ABSTRACT	The present invention relates to a method of screening a compound for potential effectiveness in treating or preventing a mammalian disease mediated by plasma cells or a mammalian disease caused by virus infection of mammalian cells. Compounds are tested for their ability to inhibit IRE1-mediated processing of untranslatable XBP-1 mRNA into translatable XBP-1 mRNA. Drugs that are useful in treating or preventing a mammalian disease mediated by plasma cells and a method for detecting XBP-1 activity in living cells are also described.
FILED	Friday, April 11, 2003
APPL NO	10/413538
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666589 — Methylation profile of breast cancer

US 07666589	Levenson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Victor V. Levenson (Chicago, Illinois); Ronald B. Gartenhaus (Northbrook, Illinois)
ABSTRACT	The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods of identifying methylation patterns in genes associated with specific cancers.
FILED	Thursday, October 02, 2003
APPL NO	10/677701
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666591 — Single stranded DNA binding proteins from Archaea and uses therefor

US 07666591	Kowalczykowski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Stephen C. Kowalczykowski (Davis, California); Frédéric Chédin (Arcadia, California); Erica M. Seitz (Davis, California)
ABSTRACT	The invention provides ssDNA-binding proteins from three species of archaeons, Methanococcus jannaschii, Methanobacter theromoautotrophicum, and Archaeoglobus fulgidus, as well as the ability to identify ssDNA-binding proteins from other archaeons. The proteins help render DNA more accessible to DNA polymerase and are robust reagents for a variety of biotechnical processes, including PCR. The invention further provides nucleic acids encoding such proteins, vectors for transfecting host cells, host cells comprising the vectors, and methods of using the proteins.
FILED	Friday, January 14, 2005
APPL NO	11/035703
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666600 — Cross-reactive primers for amplifying the nucleic acids of HIV-1 and HIV-2

US 07666600	Linnen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S)	Gen-Probe Incorporated (San Diego, California)
INVENTOR(S)	Jeffrey M. Linnen (Poway, California); Wen Wu (Carlsbad, California)
ABSTRACT	Compositions, methods and kits for detecting the nucleic acids of HIV-1, HIV-2, or the combination of HIV-1 and HIV-2. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers, including cross-reacting hybridization probes and cross-reacting amplification primers, for detecting very low levels of viral nucleic acids.
FILED	Monday, August 13, 2007
APPL NO	11/837954
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666601 — Phenylthiocarbamide (PTC) taste receptor

US 07666601	Drayna et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); The University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Dennis Drayna (Potomac, Maryland); Un-Kyung Kim (Gaithersburg, Maryland); Mark Leppert (Salt Lake City, Utah)
ABSTRACT	The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
FILED	Thursday, October 11, 2007
APPL NO	11/871131
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666607 — TRAF family proteins

US 07666607	Zapata et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Burnham Institute for Medical Research (La Jolla, California)
INVENTOR(S)	Juan M. Zapata (San Diego, California); John C. Reed (Rancho Santa Fe, California)
ABSTRACT	In accordance with the present invention, there are provided novel TRAF-Protein-Binding-Domain polypeptides (TPBDs). The invention also provides nucleic acid molecules encoding TPBDs, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention TPBDs. Such TPBDs and/or anti-TPBD antibodies are useful for discovery of drugs that suppress autoimmunity, inflammation, allergy, allograph rejection, sepsis, and other diseases.
FILED	Friday, April 20, 2007
APPL NO	11/788741
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.100
VIEW PATENT	@ USPTO: Full Text PDF

07666616 — Nucleic acid sequences encoding luciferase for expression in filamentous fungi

US 07666616	Dunlap et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Institute of Mental Health (NIMH)
APPLICANT(S)
ASSIGNEE(S)	Trustees of Dartmouth College (Hanover, New Hampshire); Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Jay C. Dunlap (Thetford, Vermont); Jennifer Loros (Thetford, Vermont); Arun Mehra (Hanover, New Hampshire); Van D. Gooch (Morris, Minnesota)
ABSTRACT	The present invention relates to genetic reporters. Specifically, the present invention is directed to a modified gene encoding a luciferase for high level expression in an organism with a bias for cytosine (C) or guanine (G) in the third position of the codon.
FILED	Friday, September 30, 2005
APPL NO	11/576168
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/8
VIEW PATENT	@ USPTO: Full Text PDF

07666658 — Antibody catalysis of enantio- and diastereo-selective aldol reactions

US 07666658	Barbas et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Carlos F. Barbas (Solana Beach, California); Richard A. Lerner (La Jolla, California); Guofu Zhong (San Diego, California)
ABSTRACT	Nine efficient aldolase antibodies were generated using hapten 2. This hapten combines, in a single molecule, structural components employed for reactive immunization with structural components employed for forming a transition state analog of the aldol reaction. Characterization of two of these antibodies reveals that they are highly proficient (up to 1000-fold better than any other antibody catalyst) and enantioselective catalysts for aldol and retro-aldol reactions and exhibit enantio- and diastereo-selectivities opposite that of antibody 38C2.
FILED	Friday, October 06, 2000
APPL NO	10/110181
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/280
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07666674 — Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo

US 07666674	Klinman et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Dennis M. Klinman (Potomac, Maryland); Ihsan Gursel (Rockville, Maryland); Ken J. Ishii (Osaka, Japan)
ABSTRACT	Sterically stabilized cationic liposomes (SSCL) encapsulating a K type oligodeoxynucleotide (ODN) including a CpG motif are disclosed. These SSCL encapuslating a K type ODN can be used to effectively deliver the ODN to a cell. A novel method is also disclosed for producing the SSCL encapsulating the K type ODN. Administration of the SSCL encapsulating a K type ODN and a chemotherapeutic agent, such as a chimeric molecule comprising a targeting molecule selected from the group consisting of an IL-13, and an anti-IL-13 receptor antibody; and an effector molecule selected from the group consisting of a Pseudomonas exotoxin, a Diphtheria toxin, and a radionuclide, can be used to dramatically reduce the growth of solid tumors.
FILED	Monday, July 29, 2002
APPL NO	10/484991
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/375
VIEW PATENT	@ USPTO: Full Text PDF

07666840 — α-Conotoxin peptides

US 07666840	Watkins et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	The University of Utah Research Foundation (Salt Lake City, Utah); Cognetix, Inc. (Salt Lake City, Utah)
INVENTOR(S)	Maren Watkins (Salt Lake City, Utah); Baldomero M. Olivera (Salt Lake City, Utah); David R. Hillyard (Salt Lake City, Utah); J. Michael McIntosh (Salt Lake City, Utah); Robert M. Jones (Salt Lake City, Utah)
ABSTRACT	The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.
FILED	Tuesday, October 09, 2007
APPL NO	11/869480
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/13
VIEW PATENT	@ USPTO: Full Text PDF

07666846 — Cholesterol-containing compounds and their use as immunogens against Borrelia burgdorferi

US 07666846	Ben-Menachem et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Gil Ben-Menachem (Rockville, Maryland); Joanna Kubler-Kielb (Rockville, Maryland); Rachel Schneerson (Bethesda, Maryland); John B. Robbins (Chevy Chase, Maryland); Vince Pozsgay (Rockville, Maryland)
ABSTRACT	Unique compounds that can be used for inducing an immune response to Borrelia burgdorferi in a subject by administering a therapeutically effective amount of the glycolipid to the subject. Such administration is particularly useful for preventing or treating Lyme disease in a subject. The compounds(s), and therapeutically acceptable salts thereof, may be formulated into pharmaceutical or immunogenic compositions.
FILED	Friday, April 02, 2004
APPL NO	10/550907
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/25
VIEW PATENT	@ USPTO: Full Text PDF

07666849 — Ribosome structure and protein synthesis inhibitors

US 07666849	Steitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Rib-X Pharmaceuticals, Inc. (New Haven, Connecticut); Yale University (New Haven, Connecticut)
INVENTOR(S)	Thomas A. Steitz (Branford, Connecticut); Peter B. Moore (North Haven, Connecticut); Joyce A. Sutcliffe (Clinton, Connecticut); Adegboyega K. Oyelere (New Haven, Connecticut); Joseph A. Ippolito (Guilford, Connecticut)
ABSTRACT	The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.
FILED	Friday, February 25, 2005
APPL NO	11/067522
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44
VIEW PATENT	@ USPTO: Full Text PDF

07667012 — Chemoselective ligation

US 07667012	Saxon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Eliana Saxon (Albany, California); Carolyn R. Bertozzi (Berkeley, California)
ABSTRACT	The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g. on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
FILED	Thursday, April 20, 2006
APPL NO	11/408605
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Organic compounds 536/17.200
VIEW PATENT	@ USPTO: Full Text PDF

07667090 — Transgenic mouse model of B cell malignancy

US 07667090	Croce
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S)	Carlo M. Croce (Columbus, Ohio)
ABSTRACT	A transgenic non-human animal, such as a mouse, has a genome that include a nucleic acid construct having at least one transcriptional regulatory sequence capable of directing expression in B cells of the animal, wherein the transcriptional regulatory sequence is operably linked to a nucleic acid encoding a miR155 gene product. A method of testing the therapeutic efficacy of an agent in treating or preventing a lymphoproliferative condition includes assessing the effect(s) of the agent on a transgenic non-human animal.
FILED	Tuesday, April 24, 2007
APPL NO	12/298221
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Multicellular living organisms and unmodified parts thereof and related processes 8/18
VIEW PATENT	@ USPTO: Full Text PDF

07667096 — Conditional sterility in plants

US 07667096	Meagher et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S)	Richard B. Meagher (Athens, Georgia); Elizabeth McKinney (Athens, Georgia); Tehryung Kim (Taejeon, South Korea)
ABSTRACT	The present disclosure provides methods, recombinant DNA molecules, recombinant host cells containing the DNA molecules, and transgenic plant cells, plant tissue and plants which contain and express at least one antisense or interference RNA specific for a thiamine biosynthetic coding sequence or a thiamine binding protein or a thiamine-degrading protein, wherein the RNA or thiamine binding protein is expressed under the regulatory control of a transcription regulatory sequence which directs expression in male and/or female reproductive tissue. These transgenic plants are conditionally sterile; i.e., they are fertile only in the presence of exogenous thiamine. Such plants are especially appropriate for use in the seed industry or in the environment, for example, for use in revegetation of contaminated soils or phytoremediation, especially when those transgenic plants also contain and express one or more chimeric genes which confer resistance to contaminants.
FILED	Thursday, June 03, 2004
APPL NO	10/559301
ART UNIT	1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Multicellular living organisms and unmodified parts thereof and related processes 8/286
VIEW PATENT	@ USPTO: Full Text PDF

07667099 — Plastid division and related genes and proteins, and methods of use

US 07667099	Osteryoung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	Board of Trustees of Michigan State University (Lansing, Michigan)
INVENTOR(S)	Katherine W. Osteryoung (Williamston, Michigan); Stanislav Vitha (Haslett, Michigan); Olga A. Koksharova (Moscow, Russian Federation); Hongbo Gao (East Lansing, Michigan)
ABSTRACT	The present invention relates to genes encoding proteins involved in prokaryotic type or plastid division and/or morphology and the encoded proteins, and in particular to isolated Ftn2 (ARC6), ARC5, and Fzo-like genes and polypeptides. The present invention also provides methods for using Ftn2 (ARC6), ARC5, and Fzo-like genes, and polypeptides.
FILED	Friday, June 20, 2003
APPL NO	10/600070
ART UNIT	1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Multicellular living organisms and unmodified parts thereof and related processes 8/298
VIEW PATENT	@ USPTO: Full Text PDF

07667210 — Wide-area fluorescence detection system for multi-photon microscopy

US 07667210	Balaban et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Robert S. Balaban (Bethesda, Maryland); Christian A. Combs (Bethesda, Maryland); Jay R. Knutson (Bethesda, Maryland)
ABSTRACT	A multi-photon microscope has an illumination source, an objective lens unit arranged in an optical path of the illumination source, a first light collection system arranged to collect a first portion of light emitted from a sample when the sample is illuminated by light from the illumination source, and a second light collection system arranged to collect a second portion of light emitted from the sample when the sample is illuminated by light from the illumination source. The first portion of light when collected by the first light collection system and the second portion of light when collected by the second light collection system, together provide a means of collecting as much light from as many angles as possible emanating from an emitting point source. This collection scheme has the potential to approach the total emission collection of light from an emitting point source depending on the optical properties of the sample being imaged.
FILED	Tuesday, November 06, 2007
APPL NO	11/979600
ART UNIT	2884 — Optics
CURRENT CPC	Radiant energy 250/458.100
VIEW PATENT	@ USPTO: Full Text PDF

07667832 — System for identifying refractive-index fluctuations of a target

US 07667832	Backman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois); NorthShore University HealthSystem (Evanston, Illinois)
INVENTOR(S)	Vadim Backman (Chicago, Illinois); Yang Liu (Somerset, New Jersey); Young Kim (West Lafayette, Indiana)
ABSTRACT	Systems and methods for identifying refractive-index fluctuations of a target are described in this application. One embodiment includes identifying one or more properties of emergent light, the emergent light to be emergent from a target, and determining refractive-index fluctuations of the target based on the one or more properties of the emergent light. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations.
FILED	Monday, August 13, 2007
APPL NO	11/891884
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/128
VIEW PATENT	@ USPTO: Full Text PDF

07667882 — Fourier transform volume holographic spectrometer

US 07667882	Adibi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Georgia Tech Research Corp. (Atlanta, Georgia)
INVENTOR(S)	Ali Adibi (Suwanee, Georgia); Chao Ray Hsieh (Atlanta, Georgia); Arash Karbaschi (Smyrna, Georgia); Omid Momtahan (Smyrna, Georgia)
ABSTRACT	One embodiment of a system includes a volume hologram for dispersing a general diffuse beam of light provided as input; a detector for receiving and detecting light dispersed by the volume hologram; and a Fourier transforming lens for forming the Fourier transform of the light dispersed from the volume hologram onto the detector. Other systems and methods are also provided.
FILED	Wednesday, October 12, 2005
APPL NO	11/248866
ART UNIT	2872 — Optics
CURRENT CPC	Optical: Systems and elements 359/15
VIEW PATENT	@ USPTO: Full Text PDF

07668351 — System and method for automation of morphological segmentation of bio-images

US 07668351	Soliz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)	Kestrel Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Peter Soliz (Albuquerque, New Mexico); Mark Wilson (Albuquerque, New Mexico); Balaji Raman (Albuquerque, New Mexico)
ABSTRACT	Medical images are automatically segmented by customizing the morphological segmentation of features identified in the image based upon statistical analysis of the features within each region to be analyzed. The statistical description of the features, as reported through a feature vector, informs the system as to which input variables to select for further segmentation analysis for features residing within the region of the image analyzed. By customizing the automatic segmentation analysis to produce an enhanced image, features within the image are characterized more efficiently and precisely. False positive identification of lesions are minimized without sacrifice of true positive identifications.
FILED	Tuesday, January 20, 2004
APPL NO	10/760923
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/128
VIEW PATENT	@ USPTO: Full Text PDF

07668357 — Method and system for using computed tomography to test pulmonary function

US 07668357	Keall et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Stanford University (Palo Alto, California)
INVENTOR(S)	Paul John Keall (Richmond, Virginia); Sarang C. Joshi (Chapel Hill, North Carolina)
ABSTRACT	Computed axial tomography images of different respiratory phases of lungs are obtained, where the intensity of the image measures lung density. One image is deformed to the coordinate space of the other image, and the differences between the intensity values of the other image as compared to the mapped image are evaluated as measures of ventilation.
FILED	Monday, October 17, 2005
APPL NO	11/250627
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/130
VIEW PATENT	@ USPTO: Full Text PDF

07668586 — In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease

US 07668586	Hyman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Cornell Research Foundation, Inc. (Ithaca, New York); The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Bradley T. Hyman (Charlestown, Massachusetts); Richard Christie (New York, New York); Brian Bacskai (Charlestown, Massachusetts); Watt W. Webb (Ithaca, New York); Warren R. Zipfel (Ithaca, New York)
ABSTRACT	The present invention is directed to a method of detecting a neurodegenerative disease in a mammal by activating brain tissue of the mammal by application of radiation under conditions effective to promote a simultaneous multiphoton excitation of the brain tissue and to emit a fluorescence characteristic. The fluorescence characteristic is then compared to a standard fluorescence emitted by exciting healthy brain tissue of the mammal under the same conditions used to carry out the activating step. Brain tissue where the fluorescence characteristic differs from the standard fluorescence is identified as potentially having a neurodegenerative disease. Another aspect of the present invention is directed to a method of producing an image of brain tissue from a mammal by activating brain tissue of a mammal with radiation applied under conditions effective to promote a simultaneous multiphoton excitation of the brain tissue and to produce fluorescence. The fluorescence is then collected to produce an image of the brain tissue.
FILED	Wednesday, October 31, 2001
APPL NO	10/001643
ART UNIT	3737 — Selective Visual Display Systems
CURRENT CPC	Surgery 6/473
VIEW PATENT	@ USPTO: Full Text PDF

07668659 — Diagnosis and classification of multiple myeloma

US 07668659	Shaughnessy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S)	John D. Shaughnessy (Little Rock, Arkansas); Bart Barlogie (Little Rock, Arkansas); Fenghuang Zhan (Little Rock, Arkansas)
ABSTRACT	Gene expression profiling between normal B cells/plasma cells and multiple myeloma cells revealed four distinct subgroups of multiple myeloma plasma cells that have significant correlation with clinical characteristics known to be associated with poor prognosis. Diagnosis for multiple myeloma (and possibly monoclonal gammopathy of undetermined significance) based on differential expression of 14 genes, as well as prognostics for the four subgroups of multiple myeloma based on the expression of 24 genes were also established. Gene expression profiling also allows placing multiple myeloma into a developmental schema parallel to that of normal plasma cell differentiation. The development of a gene expression- or developmental stage-based classification system for multiple myeloma would lead to rational design of more accurate and sensitive diagnostics, prognostics and tumor-specific therapies for multiple myeloma.
FILED	Thursday, November 07, 2002
APPL NO	10/289746
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

07668662 — Patient-specific dosimetry

US 07668662	Kroll et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan); Smithkline Beecham Corporation (Philadelphia, Pennsylvania)
INVENTOR(S)	Stewart M. Kroll (Oakland, California); Jeffry A. Siegal (Cherry Hill, New Jersey); Richard L. Wahl (Ann Arbor, Michigan); Kenneth R. Zasadny (Wyandotte, Michigan)
ABSTRACT	A patient-specific optimally effective radiation dose for administration of a radiopharmaceutical to a patient for treatment of a disease may be established by basing the calculation of the appropriate therapeutic dose on factors such as the desired total body dose, the maximum tolerated dose, the typical clearance profile of the radiopharmaceutical, the patient's mass or maximum effective mass, and the patient-specific residence time of the radiopharmaceutical or an analog in the whole body of the patient. The use of the method allows for treatment of a patient with an appropriate dose which is maximally effective against the disease yet minimally toxic. The determination of a patient-specific therapeutic dose may be assisted by the use of a software program set to the particular parameters of the radiopharmaceutical.
FILED	Wednesday, August 10, 2005
APPL NO	11/200688
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

07668697 — Method for analyzing dynamic detectable events at the single molecule level

US 07668697	Volkov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Andrei Volkov (Houston, Texas); Costa M. Colbert (Houston, Texas); Ivan Pan (Houston, Texas); Anelia Kraltcheva (Houston, Texas); Mitsu Reddy (Pearland, Texas); Nasanshargal Battulga (Houston, Texas); Michael A. Rea (Sugarland, Texas); Keun Woo Lee (Jinju, GN 660-701, South Korea); Susan H. Hardin (College Station, Texas); Brent Mulder (Grandville, Michigan); Chris Hebel (Houston, Texas); Alok Bandekar (Houston, Texas)
ABSTRACT	A method to be implemented on or in a computer is disclosed, where the method includes data collection, calibration, candidate selection, and analysis of data streams associated with each candidate to classify single molecule fluorescence resonance energy transfer events. Once classified, the classification can be related to the nature of the events, such as the identification of dNTP incorporation during primer extension to obtain a base read out of an unknown template.
FILED	Tuesday, February 06, 2007
APPL NO	11/671956
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/187
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

07665309 — Secondary fuel delivery system

US 07665309	Parker et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S)	David M. Parker (Oviedo, Florida); Weidong Cai (Oviedo, Florida); Daniel W. Garan (Orlando, Florida); Arthur J. Harris (Orlando, Florida)
ABSTRACT	A secondary fuel delivery system for delivering a secondary stream of fuel and/or diluent to a secondary combustion zone located in the transition piece of a combustion engine, downstream of the engine primary combustion region is disclosed. The system includes a manifold formed integral to, and surrounding a portion of, the transition piece, a manifold inlet port, and a collection of injection nozzles. A flowsleeve augments fuel/diluent flow velocity and improves the system cooling effectiveness. Passive cooling elements, including effusion cooling holes located within the transition boundary and thermal-stress-dissipating gaps that resist thermal stress accumulation, provide supplemental heat dissipation in key areas. The system delivers a secondary fuel/diluent mixture to a secondary combustion zone located along the length of the transition piece, while reducing the impact of elevated vibration levels found within the transition piece and avoiding the heat dissipation difficulties often associated with traditional vibration reduction methods.
FILED	Monday, September 15, 2008
APPL NO	12/210356
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/776
VIEW PATENT	@ USPTO: Full Text PDF

07665328 — Method of producing hydrogen, and rendering a contaminated biomass inert

US 07665328	Bingham et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Klingler (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho)
ABSTRACT	A method for rendering a contaminated biomass inert includes providing a first composition, providing a second composition, reacting the first and second compositions together to form an alkaline hydroxide, providing a contaminated biomass feedstock and reacting the alkaline hydroxide with the contaminated biomass feedstock to render the contaminated biomass feedstock inert and further producing hydrogen gas, and a byproduct that includes the first composition.
FILED	Monday, June 19, 2006
APPL NO	11/425088
ART UNIT	1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Refrigeration 062/607
VIEW PATENT	@ USPTO: Full Text PDF

07665364 — Method and apparatus for remote sensing of molecular species at nanoscale utilizing a reverse photoacoustic effect

US 07665364	Su et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Ming Su (Oviedo, Florida); Thomas G. Thundat (Knoxville, Tennessee); David Hedden (Lenoir City, Tennessee)
ABSTRACT	A method and apparatus for identifying a sample, involves illuminating the sample with light of varying wavelengths, transmitting an acoustic signal against the sample from one portion and receiving a resulting acoustic signal on another portion, detecting a change of phase in the acoustic signal corresponding to the light of varying wavelengths, and analyzing the change of phase in the acoustic signal for the varying wavelengths of illumination to identify the sample. The apparatus has a controlled source for illuminating the sample with light of varying wavelengths, a transmitter for transmitting an acoustic wave, a receiver for receiving the acoustic wave and converting the acoustic wave to an electronic signal, and an electronic circuit for detecting a change of phase in the acoustic wave corresponding to respective ones of the varying wavelengths and outputting the change of phase for the varying wavelengths to allow identification of the sample. The method and apparatus can be used to detect chemical composition or visual features. A transmission mode and a reflection mode of operation are disclosed. The method and apparatus can be applied at nanoscale to detect molecules in a biological sample.
FILED	Thursday, December 14, 2006
APPL NO	11/639184
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/643
VIEW PATENT	@ USPTO: Full Text PDF

07665431 — Drive piston assembly for a valve actuator assembly

US 07665431	Sun
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	GM Global Technology Operations, Inc. (Detroit, Michigan)
INVENTOR(S)	Zongxuan Sun (Troy, Michigan)
ABSTRACT	A drive piston assembly is provided that is operable to selectively open a poppet valve. The drive piston assembly includes a cartridge defining a generally stepped bore. A drive piston is movable within the generally stepped bore and a boost sleeve is coaxially disposed with respect to the drive piston. A main fluid chamber is at least partially defined by the generally stepped bore, drive piston, and boost sleeve. First and second feedback chambers are at least partially defined by the drive piston and each are disposed at opposite ends of the drive piston. At least one of the drive piston and the boost sleeve is sufficiently configured to move within the generally stepped bore in response to fluid pressure within the main fluid chamber to selectively open the poppet valve. A valve actuator assembly and engine are also provided incorporating the disclosed drive piston assembly.
FILED	Wednesday, October 11, 2006
APPL NO	11/548297
ART UNIT	3748 — Printing/Measuring and Testing
CURRENT CPC	Internal-combustion engines 123/90.120
VIEW PATENT	@ USPTO: Full Text PDF

07665524 — Liquid metal heat exchanger for efficient heating of soils and geologic formations

US 07665524	DeVault et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Robert C. DeVault (Knoxville, Tennessee); David J. Wesolowski (Kingston, Tennessee)
ABSTRACT	Apparatus for efficient heating of subterranean earth includes a well-casing that has an inner wall and an outer wall. A heater is disposed within the inner wall and is operable within a preselected operating temperature range. A heat transfer metal is disposed within the outer wall and without the inner wall, and is characterized by a melting point temperature lower than the preselected operating temperature range and a boiling point temperature higher than the preselected operating temperature range.
FILED	Friday, September 29, 2006
APPL NO	11/536988
ART UNIT	3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Wells 166/302
VIEW PATENT	@ USPTO: Full Text PDF

07665844 — High-resolution adaptive optics scanning laser ophthalmoscope with multiple deformable mirrors

US 07665844	Chen et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security LLC (Livermore, California)
INVENTOR(S)	Diana C. Chen (Fremont, California); Scot S. Olivier (Livermore, California); Steven M. Jones (Livermore, California)
ABSTRACT	An adaptive optics scanning laser ophthalmoscopes is introduced to produce non-invasive views of the human retina. The use of dual deformable mirrors improved the dynamic range for correction of the wavefront aberrations compared with the use of the MEMS mirror alone, and improved the quality of the wavefront correction compared with the use of the bimorph mirror alone. The large-stroke bimorph deformable mirror improved the capability for axial sectioning with the confocal imaging system by providing an easier way to move the focus axially through different layers of the retina.
FILED	Thursday, October 18, 2007
APPL NO	11/874832
ART UNIT	2873 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Optics: Eye examining, vision testing and correcting 351/206
VIEW PATENT	@ USPTO: Full Text PDF

07665858 — Optical manifold

US 07665858	Falicoff et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Waqidi Falicoff (Stevenson Ranch, California); Julio C. Chaves (Madrid, Spain); Juan Carlos Miñano (Madrid, Spain); Pablo Benítez (Madrid, Spain); Oliver Dross (Madrid, Spain); William A. Parkyn, Jr. (Lomita, California)
ABSTRACT	Optical systems are described that have at least one source of a beam of blue light with divergence under 15°. A phosphor emits yellow light when excited by the blue light. A collimator is disposed with the phosphor and forms a yellow beam with divergence under 15°. A dichroic filter is positioned to transmit the beam of blue light to the phosphor and to reflect the beam of yellow light to an exit aperture. In different embodiments, the beams of blue and yellow light are incident upon said filter with central angles of 15°, 22°, and 45°. The filter may reflect all of one polarization and part of the other polarization, and a polarization rotating retroreflector may then be provided to return the unreflected light to the filter.
FILED	Friday, November 02, 2007
APPL NO	11/982480
ART UNIT	2875 — Optics
CURRENT CPC	Illumination 362/84
VIEW PATENT	@ USPTO: Full Text PDF

07666051 — Device and method for achieving enhanced field emission utilizing nanostructures grown on a conductive substrate

US 07666051	Ren et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Soldier Center (CCDC SC) Research, Development and Engineering Command (RDECOM) Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S)	Zhifeng Ren (Newton, Massachusetts); Sung Ho Jo (Chestnut Hill, Massachusetts); Debasish Banerjee (Chestnut Hill, Massachusetts)
ABSTRACT	A device and method is presented for achieving a high field emission from the application of a low electric field. More specifically, the device includes a substrate wherein a plurality of nanostructures are grown on the substrate. The relationship of the nanostructures and the substrate (the relationship includes the number of nanostructures on the substrate, the orientation of the nanostructures in relationship to each other and in relationship to the substrate, the geometry of the substrate, the morphology of the nanostructures and the morphology of the substrate, the manner in which nanostructures are grown on the substrate, the composition of nanostructure and composition of substrate, etc) allow for the generation of the high field emission from the application of the low electric field.
FILED	Tuesday, January 09, 2007
APPL NO	11/651267
ART UNIT	2889 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Electric lamp or space discharge component or device manufacturing 445/49
VIEW PATENT	@ USPTO: Full Text PDF

07666250 — Production of magnesium metal

US 07666250	Blencoe et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tenessee Research Foundation (Knoxville, Texas); Virginia Museum of Natural History Foundation (Martinsville, Virginia)
INVENTOR(S)	James G. Blencoe (Harriman, Tennessee); Lawrence M. Anovitz (Knoxville, Tennessee); Donald A. Palmer (Oliver Springs, Tennessee); James S. Beard (Martinsville, Virginia)
ABSTRACT	A process of producing magnesium metal includes providing magnesium carbonate, and reacting the magnesium carbonate to produce a magnesium-containing compound and carbon dioxide. The magnesium-containing compound is reacted to produce magnesium metal. The carbon dioxide is used as a reactant in a second process. In another embodiment of the process, a magnesium silicate is reacted with a caustic material to produce magnesium hydroxide. The magnesium hydroxide is reacted with a source of carbon dioxide to produce magnesium carbonate. The magnesium carbonate is reacted to produce a magnesium-containing compound and carbon dioxide. The magnesium-containing compound is reacted to produce magnesium metal. The invention further relates to a process for production of magnesium metal or a magnesium compound where an external source of carbon dioxide is not used in any of the reactions of the process. The invention also relates to the magnesium metal produced by the processes described herein.
FILED	Friday, April 29, 2005
APPL NO	11/119536
ART UNIT	1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/594
VIEW PATENT	@ USPTO: Full Text PDF

07666289 — Methods and devices for high-throughput dielectrophoretic concentration

US 07666289	Simmons et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Livermore, California)
INVENTOR(S)	Blake A. Simmons (San Francisco, California); Eric B. Cummings (Livermore, California); Gregory J. Fiechtner (Germantown, Maryland); Yolanda Fintschenko (Livermore, California); Gregory J. McGraw (Ann Arbor, Michigan); Allen Salmi (Escalon, California)
ABSTRACT	Disclosed herein are methods and devices for assaying and concentrating analytes in a fluid sample using dielectrophoresis. As disclosed, the methods and devices utilize substrates having a plurality of pores through which analytes can be selectively prevented from passing, or inhibited, on application of an appropriate electric field waveform. The pores of the substrate produce nonuniform electric field having local extrema located near the pores. These nonuniform fields drive dielectrophoresis, which produces the inhibition. Arrangements of electrodes and porous substrates support continuous, bulk, multi-dimensional, and staged selective concentration.
FILED	Tuesday, September 02, 2008
APPL NO	12/202489
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry: Electrical and wave energy 24/643
VIEW PATENT	@ USPTO: Full Text PDF

07666387 — Carbonate thermochemical cycle for the production of hydrogen

US 07666387	Collins et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Jack L Collins (Knoxville, Tennessee); Leslie R Dole (Knoxville, Tennessee); Juan J Ferrada (Knoxville, Tennessee); Charles W Forsberg (Oak Ridge, Tennessee); Marvin J Haire (Oak Ridge, Tennessee); Rodney D Hunt (Oak Ridge, Tennessee); Benjamin E Lewis, Jr. (Knoxville, Tennessee); Raymond G Wymer (Oak Ridge, Tennessee)
ABSTRACT	The present invention is directed to a thermochemical method for the production of hydrogen from water. The method includes reacting a multi-valent metal oxide, water and a carbonate to produce an alkali metal-multi-valent metal oxide compound, carbon dioxide, and hydrogen.
FILED	Friday, October 19, 2007
APPL NO	11/874958
ART UNIT	1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry of inorganic compounds 423/657
VIEW PATENT	@ USPTO: Full Text PDF

07666424 — Methods of preparing and using single chain anti-tumor antibodies

US 07666424	Cheung et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S)	Nai-Kong Cheung (Purchase, New York); Hong-Fen Guo (New York, New York)
ABSTRACT	This invention provides a method for identifying cells expressing a target single chain antibody (scFv) directed against a target antigen from a collection of cells that includes cells that do not express the target scFv, comprising the step of combining the collection of cells with an anti-idiotype directed to an antibody specific for the target antigen and detecting interaction, if any, of the anti-idiotype with the cells, wherein the occurrence of an interaction identifies the cell as one which expresses the target scFv. This invention also provides a method for making a single chain antibody (scFv) directed against an antigen, wherein the selection of clones is made based upon interaction of those clones with an appropriate anti-idiotype, and heretofore inaccessible scFv so made. This invention provides the above methods or any combination thereof. Finally, this invention provides various uses of these methods.
FILED	Thursday, October 17, 2002
APPL NO	10/273762
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/178.100
VIEW PATENT	@ USPTO: Full Text PDF

07666463 — Methods for manufacturing porous nuclear fuel elements for high-temperature gas-cooled nuclear reactors

US 07666463	Youchison et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Dennis L. Youchison (Albuquerque, New Mexico); Brian E. Williams (Pocoima, California); Robert E. Benander (Pacoima, California)
ABSTRACT	Methods for manufacturing porous nuclear fuel elements for use in advanced high temperature gas-cooled nuclear reactors (HTGR's). Advanced uranium bi-carbide, uranium tri-carbide and uranium carbonitride nuclear fuels can be used. These fuels have high melting temperatures, high thermal conductivity, and high resistance to erosion by hot hydrogen gas. Tri-carbide fuels, such as (U,Zr,Nb)C, can be fabricated using chemical vapor infiltration (CVI) to simultaneously deposit each of the three separate carbides, e.g., UC, ZrC, and NbC in a single CVI step. By using CVI, a thin coating of nuclear fuel may be deposited inside of a highly porous skeletal structure made, for example, of reticulated vitreous carbon foam.
FILED	Wednesday, May 17, 2006
APPL NO	11/435412
ART UNIT	1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Coating processes 427/5
VIEW PATENT	@ USPTO: Full Text PDF

07666534 — Electro-catalytic oxidation device for removing carbon from a fuel reformate

US 07666534	Liu
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S)	The United States of America as Represented by the Untied States Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Di-Jia Liu (Naperville, Illinois)
ABSTRACT	An electro-catalytic oxidation device (ECOD) for the removal of contaminates, preferably carbonaceous materials, from an influent comprising an ECOD anode, an ECOD cathode, and an ECOD electrolyte. The ECOD anode is at a temperature whereby the contaminate collects on the surface of the ECOD anode as a buildup. The ECOD anode is electrically connected to the ECOD cathode, which consumes the buildup producing electricity and carbon dioxide. The ECOD anode is porous and chemically active to the electro-catalytic oxidation of the contaminate. The ECOD cathode is exposed to oxygen, and made of a material which promotes the electro-chemical reduction of oxygen to oxidized ions. The ECOD electrolyte is non-permeable to gas, electrically insulating and a conductor to oxidized. The ECOD anode is connected to the fuel reformer and the fuel cell. The ECOD electrolyte is between and in ionic contact with the ECOD anode and the ECOD cathode.
FILED	Tuesday, September 19, 2006
APPL NO	11/532928
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/21
VIEW PATENT	@ USPTO: Full Text PDF

07666583 — Identification of cancer protein biomarkers using proteomic techniques

US 07666583	Mor et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Gil G. Mor (Cheshire, Connecticut); David C. Ward (Las Vegas, Nevada); Patricia Bray-Ward (Las Vegas, Nevada)
ABSTRACT	The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.
FILED	Tuesday, January 18, 2005
APPL NO	11/037889
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

07666606 — Protein- protein interaction detection system using fluorescent protein microdomains

US 07666606	Waldo et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS)
APPLICANT(S)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Geoffrey S. Waldo (Santa Fe, New Mexico); Stephanie Cabantous (Los Alamos, New Mexico)
ABSTRACT	The invention provides a protein labeling and interaction detection system based on engineered fragments of fluorescent and chromophoric proteins that require fused interacting polypeptides to drive the association of the fragments, and further are soluble and stable, and do not change the solubility of polypeptides to which they are fused. In one embodiment, a test protein X is fused to a sixteen amino acid fragment of GFP (β-strand 10, amino acids 198-214), engineered to not perturb fusion protein solubility. A second test protein Y is fused to a sixteen amino acid fragment of GFP (β-strand 11, amino acids 215-230), engineered to not perturb fusion protein solubility. When X and Y interact, they bring the GFP strands into proximity, and are detected by complementation with a third GFP fragment consisting of GFP amino acids 1-198 (strands 1-9). When GFP strands 10 and 11 are held together by interaction of protein X and Y, they spontaneous association with GFP strands 1-9, resulting in structural complementation, folding, and concomitant GFP fluorescence.
FILED	Monday, December 05, 2005
APPL NO	11/295368
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.100
VIEW PATENT	@ USPTO: Full Text PDF

07666648 — Isolated polypeptide having arabinofuranosidase activity

US 07666648

Foreman et al.

FUNDED BY

Department of Energy (DOE): Office of Energy Efficiency and Renewable Energy (EERE); National Renewable Energy Laboratory (NREL); Federally Funded Research and Development Center (FFRDC); Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO

APPLICANT(S)

ASSIGNEE(S)

Danisco US Inc. (Palo Alto, California)

INVENTOR(S)

Pamela Foreman (Palo Alto, California); Pieter Van Solingen (Naaldwijk, Netherlands); Frits Goedegebuur (Vlaardingen, Netherlands); Michael Ward (Palo Alto, California)

ABSTRACT

Described herein are novel gene sequences isolated from Trichoderma reesei. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2, contain a cellulose binding domain. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry. cip1 cDNA sequence (SEQ ID NO: 1) GACTAGTTCA TAATACAGTA GTTGAGTTCA TAGCAACTTC 50 ACTCTCTAGC TGAACAAATT ATCTGCGCAA ACATGGTTCG CCGGACTGCT 100 CTGCTGGCCC TTGGGGCTCT CTCAACGCTC TCTATGGCCC AAATCTCAGA 150 CGACTTCGAG TCGGGCTGGG ATCAGACTAA ATGGCCCATT TCGGCACCAG 200 ACTGTAACCA GGGCGGCACC GTCAGCCTCG ACACCACAGT AGCCCACAGC 250 GGCAGCAACT CCATGAAGGT CGTTGGTGGC CCCAATGGCT ACTGTGGACA 300 CATCTTCTTC GGCACTACCC AGGTGCCAAC TGGGGATGTA TATGTCAGAG 350 CTTGGATTCG GCTTCAGACT GCTCTCGGCA GCAACCACGT CACATTCATC 400 ATCATGCCAG ACACCGCTCA GGGAGGGAAG CACCTCCGAA TTGGTGGCCA 450 AAGCCAAGTT CTCGACTACA ACCGCGAGTC CGACGATGCC ACTCTTCCGG 500 ACCTGTCTCC CAACGGCATT GCCTCCACCG TCACTCTGCC TACCGGCGCG 550 TTCCAGTGCT TCGAGTACCA CCTGGGCACT GACGGAACCA TCGAGACGTG 600 GCTCAACGGC AGCCTCATCC CGGGCATGAC CGTGGGCCCT GGCGTCGACA 650 ATCCAAACGA CGCTGGCTGG ACGAGGGCCA GCTATATTCC GGAGATCACC 700 GGTGTCAACT TTGGCTGGGA GGCCTACAGC GGAGACGTCA ACACCGTCTG 750 GTTCGACGAC ATCTCGATTG CGTCGACCCG CGTGGGATGC GGCCCCGGCA 800 GCCCCGGCGG TCCTGGAAGC TCGACGACTG GGCGTAGCAG CACCTCGGGC 850 CCGACGAGCA CTTCGAGGCC AAGCACCACC ATTCCGCCAC CGACTTCCAG 900 GACAACGACC GCCACGGGTC CGACTCAGAC ACACTATGGC CAGTGCGGAG 1000 GGATTGGTTA CAGCGGGCCT ACGGTCTGCG CGAGCGGCAC GACCTGCCAG 1050 GTCCTGAACC CATACTACTC CCAGTGCTTA TAAGGGGATG AGCATGGAGT 1100 GAAGTGAAGT GAAGTGGAGA GAGTTGAAGT GGCATTGCGC TCGGCTGGGT 1150 AGATAAAAGT CAGCAGCTAT GAATACTCTA TGTGATGCTC ATTGGCGTGT 1200 ACGTTTTAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 1250 AAAAAAAAAA AAAAAAAAAG GGGGCGGCCG C 1271

FILED

Friday, May 28, 2004

APPL NO

10/555358

ART UNIT

1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes

CURRENT CPC

Chemistry: Molecular biology and microbiology
435/200

VIEW PATENT

@ USPTO: Full Text PDF

07666807 — Hollow porous-wall glass microspheres for hydrogen storage

US 07666807	Heung et al.
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)
ASSIGNEE(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S)	Leung K. Heung (Aiken, South Carolina); Ray F. Schumacher (Aiken, South Carolina); George G. Wicks (Aiken, South Carolina)
ABSTRACT	A porous wall hollow glass microsphere is provided having a diameter range of between 1 to 200 microns, a density of between 1.0 to 2.0 gm/cc, a porous-wall structure having wall openings defining an average pore size of between 10 to 1000 angstroms, and which contains therein a hydrogen storage material. The porous-wall structure facilitates the introduction of a hydrogen storage material into the interior of the porous wall hollow glass microsphere. In this manner, the resulting hollow glass microsphere can provide a membrane for the selective transport of hydrogen through the porous walls of the microsphere, the small pore size preventing gaseous or liquid contaminants from entering the interior of the hollow glass microsphere.
FILED	Friday, October 21, 2005
APPL NO	11/256442
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Catalyst, solid sorbent, or support therefor: Product or process of making 52/8
VIEW PATENT	@ USPTO: Full Text PDF

07666818 — Combinatorial synthesis of ceramic materials

US 07666818	Lauf et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Robert J. Lauf (Oak Ridge, Tennessee); Claudia A. Walls (Oak Ridge, Tennessee); Lynn A. Boatner (Oak Ridge, Tennessee)
ABSTRACT	A combinatorial library includes a gelcast substrate defining a plurality of cavities in at least one surface thereof; and a plurality of gelcast test materials in the cavities, at least two of the test materials differing from the substrate in at least one compositional characteristic, the two test materials differing from each other in at least one compositional characteristic.
FILED	Monday, March 13, 2006
APPL NO	11/374235
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Combinatorial chemistry technology: Method, library, apparatus 56/13
VIEW PATENT	@ USPTO: Full Text PDF

07666850 — Drug screens based on the newly found role of dystroglycan proteolysis and restoration of dystroglycan function thereof

US 07666850	Bissell et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Mina J. Bissell (Berkeley, California); John L. Muschler (Albany, California)
ABSTRACT	The present invention provides methods and compositions for the diagnosis and treatment of cells lacking normal growth arresting characteristic. The present invention demonstrates that many tumor cells lack normal cell surface α-dystroglycan and thereby lack dystroglycan function. Dystroglycan can be lost from the cell surface by proteolytic shedding of a fragment of α-dystroglycan into the surrounding medium. Upon restoration of dystroglycan function and over-expression of the dystroglycan gene, the once tumorigenic cells revert to non-tumorigenic cells which polarize and arrest cell growth in the presence of basement membrane proteins, demonstrating that dystroglycan functions as a tumor marker and suppressor.
FILED	Thursday, June 09, 2005
APPL NO	11/150406
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44
VIEW PATENT	@ USPTO: Full Text PDF

07667012 — Chemoselective ligation

US 07667012	Saxon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Eliana Saxon (Albany, California); Carolyn R. Bertozzi (Berkeley, California)
ABSTRACT	The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g. on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
FILED	Thursday, April 20, 2006
APPL NO	11/408605
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Organic compounds 536/17.200
VIEW PATENT	@ USPTO: Full Text PDF

07667096 — Conditional sterility in plants

US 07667096	Meagher et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S)	Richard B. Meagher (Athens, Georgia); Elizabeth McKinney (Athens, Georgia); Tehryung Kim (Taejeon, South Korea)
ABSTRACT	The present disclosure provides methods, recombinant DNA molecules, recombinant host cells containing the DNA molecules, and transgenic plant cells, plant tissue and plants which contain and express at least one antisense or interference RNA specific for a thiamine biosynthetic coding sequence or a thiamine binding protein or a thiamine-degrading protein, wherein the RNA or thiamine binding protein is expressed under the regulatory control of a transcription regulatory sequence which directs expression in male and/or female reproductive tissue. These transgenic plants are conditionally sterile; i.e., they are fertile only in the presence of exogenous thiamine. Such plants are especially appropriate for use in the seed industry or in the environment, for example, for use in revegetation of contaminated soils or phytoremediation, especially when those transgenic plants also contain and express one or more chimeric genes which confer resistance to contaminants.
FILED	Thursday, June 03, 2004
APPL NO	10/559301
ART UNIT	1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Multicellular living organisms and unmodified parts thereof and related processes 8/286
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07667133 — Hybrid window layer for photovoltaic cells

US 07667133	Deng
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S)	The University of Toledo (Toledo, Ohio)
INVENTOR(S)	Xunming Deng (Syvania, Ohio)
ABSTRACT	A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.
FILED	Wednesday, October 29, 2003
APPL NO	10/696545
ART UNIT	1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Batteries: Thermoelectric and photoelectric 136/255
VIEW PATENT	@ USPTO: Full Text PDF

07667200 — Thermal microphotonic sensor and sensor array

US 07667200	Watts et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Michael R. Watts (Albuquerque, New Mexico); Michael J. Shaw (Tijeras, New Mexico); Gregory N. Nielson (Albuquerque, New Mexico); Anthony L. Lentine (Albuquerque, New Mexico)
ABSTRACT	A thermal microphotonic sensor is disclosed for detecting infrared radiation using heat generated by the infrared radiation to shift the resonant frequency of an optical resonator (e.g. a ring resonator) to which the heat is coupled. The shift in the resonant frequency can be determined from light in an optical waveguide which is evanescently coupled to the optical resonator. An infrared absorber can be provided on the optical waveguide either as a coating or as a plate to aid in absorption of the infrared radiation. In some cases, a vertical resonant cavity can be formed about the infrared absorber to further increase the absorption of the infrared radiation. The sensor can be formed as a single device, or as an array for imaging the infrared radiation.
FILED	Wednesday, December 05, 2007
APPL NO	11/950821
ART UNIT	2884 — Optics
CURRENT CPC	Radiant energy 250/338.100
VIEW PATENT	@ USPTO: Full Text PDF

07667383 — Light source comprising a common substrate, a first led device and a second led device

US 07667383	Choong
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Osram Opto Semiconductors GmbH (Regensburg, Germany)
INVENTOR(S)	Vi-En Choong (Carlsbad, California)
ABSTRACT	At least one stacked organic or polymeric light emitting diode (PLEDs) devices to comprise a light source is disclosed. At least one of the PLEDs includes a patterned cathode which has regions which transmit light. The patterned cathodes enable light emission from the PLEDs to combine together. The light source may be top or bottom emitting or both.
FILED	Wednesday, February 15, 2006
APPL NO	11/356389
ART UNIT	2889 — Optics
CURRENT CPC	Electric lamp and discharge devices 313/498
VIEW PATENT	@ USPTO: Full Text PDF

07667482 — Inductively powered power bus apparatus

US 07667482	Mort et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Eaton Corporation (Cleveland, Ohio)
INVENTOR(S)	Deborah K. Mort (Coraopolis, Pennsylvania); Carlos H. Rentel (Sussex, Wisconsin); Brian Thomas Pier (Milwaukee, Wisconsin)
ABSTRACT	An apparatus for a power bus includes an inductive power harvesting unit structured to provide a first power output arising from current flowing in the power bus, an energy storage unit structured to store energy from the first power output and to provide a second power output, and a selector structured to select one of the first and second power outputs and to provide a third power output from the selected one. A processor is powered from the third power output of the selector. The selector is further structured to normally provide the third power output from the first power output of the inductive power harvesting unit. The processor is structured to determine that the first power output of the inductive power harvesting unit is inadequate and to cause the selector to provide the third power output from the second power output of the energy storage unit.
FILED	Friday, September 21, 2007
APPL NO	11/859366
ART UNIT	2829 — Semiconductors/Memory
CURRENT CPC	Electricity: Measuring and testing 324/771
VIEW PATENT	@ USPTO: Full Text PDF

07667833 — Alignment method for parabolic trough solar concentrators

US 07667833	Diver
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Richard B. Diver (Albuquerque, New Mexico)
ABSTRACT	A Theoretical Overlay Photographic (TOP) alignment method uses the overlay of a theoretical projected image of a perfectly aligned concentrator on a photographic image of the concentrator to align the mirror facets of a parabolic trough solar concentrator. The alignment method is practical and straightforward, and inherently aligns the mirror facets to the receiver. When integrated with clinometer measurements for which gravity and mechanical drag effects have been accounted for and which are made in a manner and location consistent with the alignment method, all of the mirrors on a common drive can be aligned and optimized for any concentrator orientation.
FILED	Tuesday, June 12, 2007
APPL NO	11/761396
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/138
VIEW PATENT	@ USPTO: Full Text PDF

07667854 — Hand-held survey probe

US 07667854	Young et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Kevin L. Young (Idaho Falls, Idaho); Kevin E. Hungate (Idaho Falls, Idaho)
ABSTRACT	A system for providing operational feedback to a user of a detection probe may include an optical sensor to generate data corresponding to a position of the detection probe with respect to a surface; a microprocessor to receive the data; a software medium having code to process the data with the microprocessor and pre-programmed parameters, and making a comparison of the data to the parameters; and an indicator device to indicate results of the comparison. A method of providing operational feedback to a user of a detection probe may include generating output data with an optical sensor corresponding to the relative position with respect to a surface; processing the output data, including comparing the output data to pre-programmed parameters; and indicating results of the comparison.
FILED	Monday, December 18, 2006
APPL NO	11/612023
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/614
VIEW PATENT	@ USPTO: Full Text PDF

07667942 — Battery switch for downhole tools

US 07667942	Boling
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Schlumberger Technology Corporation (Sugar Land, Texas)
INVENTOR(S)	Brian E. Boling (Sugar Land, Texas)
ABSTRACT	An electrical circuit for a downhole tool may include a battery, a load electrically connected to the battery, and at least one switch electrically connected in series with the battery and to the load. The at least one switch may be configured to close when a tool temperature exceeds a selected temperature.
FILED	Monday, December 13, 2004
APPL NO	10/905050
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Electrical systems and devices 361/103
VIEW PATENT	@ USPTO: Full Text PDF

07668621 — Robotic guarded motion system and method

US 07668621	Bruemmer
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S)	David J. Bruemmer (Idaho Falls, Idaho)
ABSTRACT	A robot platform includes perceptors, locomotors, and a system controller. The system controller executes instructions for repeating, on each iteration through an event timing loop, the acts of defining an event horizon, detecting a range to obstacles around the robot, and testing for an event horizon intrusion. Defining the event horizon includes determining a distance from the robot that is proportional to a current velocity of the robot and testing for the event horizon intrusion includes determining if any range to the obstacles is within the event horizon. Finally, on each iteration through the event timing loop, the method includes reducing the current velocity of the robot in proportion to a loop period of the event timing loop if the event horizon intrusion occurs.
FILED	Wednesday, July 05, 2006
APPL NO	11/428769
ART UNIT	3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Generic control systems or specific applications 7/245
VIEW PATENT	@ USPTO: Full Text PDF

07668831 — Assigning unique identification numbers to new user accounts and groups in a computing environment with multiple registries

US 07668831	DeRobertis et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Christopher V. DeRobertis (Hopewell Junction, New York); Yantian T. Lu (Round Rock, Texas)
ABSTRACT	A method, system, and program storage device for creating a new user account or user group with a unique identification number in a computing environment having multiple user registries is provided. In response to receiving a command to create a new user account or user group, an operating system of a clustered computing environment automatically checks multiple registries configured for the operating system to determine whether a candidate identification number for the new user account or user group has been assigned already to one or more existing user accounts or groups, respectively. The operating system automatically assigns the candidate identification number to the new user account or user group created in a target user registry if the checking indicates that the candidate identification number has not been assigned already to any of the existing user accounts or user groups, respectively.
FILED	Thursday, October 27, 2005
APPL NO	11/260796
ART UNIT	2164 — Data Bases & File Management
CURRENT CPC	Data processing: Database and file management or data structures 77/9
VIEW PATENT	@ USPTO: Full Text PDF

07668970 — Optimized scalable network switch

US 07668970	Blumrich et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Matthias A. Blumrich (Ridgefield, Connecticut); Dong Chen (Croton on Hudson, New York); Paul W. Coteus (Yorktown Heights, New York)
ABSTRACT	In a massively parallel computing system having a plurality of nodes configured in m multi-dimensions, each node including a computing device, a method for routing packets towards their destination nodes is provided which includes generating at least one of a 2m plurality of compact bit vectors containing information derived from downstream nodes. A multilevel arbitration process in which downstream information stored in the compact vectors, such as link status information and fullness of downstream buffers, is used to determine a preferred direction and virtual channel for packet transmission. Preferred direction ranges are encoded and virtual channels are selected by examining the plurality of compact bit vectors. This dynamic routing method eliminates the necessity of routing tables, thus enhancing scalability of the switch.
FILED	Friday, October 05, 2007
APPL NO	11/868223
ART UNIT	2455 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Multicomputer data transferring 79/238
VIEW PATENT	@ USPTO: Full Text PDF

07669012 — Insertion of coherence requests for debugging a multiprocessor

US 07669012	Blumrich et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Matthias A. Blumrich (Ridgefield, Connecticut); Valentina Salapura (Chappaqua, New York)
ABSTRACT	A method and system are disclosed to insert coherence events in a multiprocessor computer system, and to present those coherence events to the processors of the multiprocessor computer system for analysis and debugging purposes. The coherence events are inserted in the computer system by adding one or more special insert registers. By writing into the insert registers, coherence events are inserted in the multiprocessor system as if they were generated by the normal coherence protocol. Once these coherence events are processed, the processing of coherence events can continue in the normal operation mode.
FILED	Tuesday, June 26, 2007
APPL NO	11/768547
ART UNIT	2189 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Memory 711/146
VIEW PATENT	@ USPTO: Full Text PDF

07669075 — Row fault detection system

US 07669075	Archer et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Charles Jens Archer (Rochester, Minnesota); Kurt Walter Pinnow (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian Edward Smith (Rochester, Minnesota)
ABSTRACT	An apparatus and program product check for nodal faults in a row of nodes by causing each node in the row to concurrently communicate with its adjacent neighbor nodes in the row. The communications are analyzed to determine a presence of a faulty node or connection.
FILED	Monday, August 25, 2008
APPL NO	12/197556
ART UNIT	2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Error detection/correction and fault detection/recovery 714/4
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

07666051 — Device and method for achieving enhanced field emission utilizing nanostructures grown on a conductive substrate

US 07666051	Ren et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Soldier Center (CCDC SC) Research, Development and Engineering Command (RDECOM) Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S)	Zhifeng Ren (Newton, Massachusetts); Sung Ho Jo (Chestnut Hill, Massachusetts); Debasish Banerjee (Chestnut Hill, Massachusetts)
ABSTRACT	A device and method is presented for achieving a high field emission from the application of a low electric field. More specifically, the device includes a substrate wherein a plurality of nanostructures are grown on the substrate. The relationship of the nanostructures and the substrate (the relationship includes the number of nanostructures on the substrate, the orientation of the nanostructures in relationship to each other and in relationship to the substrate, the geometry of the substrate, the morphology of the nanostructures and the morphology of the substrate, the manner in which nanostructures are grown on the substrate, the composition of nanostructure and composition of substrate, etc) allow for the generation of the high field emission from the application of the low electric field.
FILED	Tuesday, January 09, 2007
APPL NO	11/651267
ART UNIT	2889 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Electric lamp or space discharge component or device manufacturing 445/49
VIEW PATENT	@ USPTO: Full Text PDF

07666378 — High quantum yield white phosphors and methods of making

US 07666378	Meltzer et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S)	Richard S. Meltzer (Athens, Georgia); Sergey Feofilov (Petersburg, Russian Federation); Yi Zhou (Athens, Georgia)
ABSTRACT	Embodiments of the present disclosure include a composition comprising a Gd³⁺-Eu³⁺ white phosphor composition, methods of making the composition, and the like.
FILED	Monday, July 07, 2008
APPL NO	12/217587
ART UNIT	1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemistry of inorganic compounds 423/263
VIEW PATENT	@ USPTO: Full Text PDF

07666526 — Non-volatile resistance-switching oxide thin film devices

US 07666526	Chen et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	I-Wei Chen (Swarthmore, Pennsylvania); Yudi Wang (Drexel Hill, Pennsylvania); Soo Gil Kim (Drexel Hill, Pennsylvania)
ABSTRACT	Non-volatile resistance-switching oxide films, and devices therewith, are disclosed. One embodiment of a suitable device is composed of a SRO-CZO thin film having a thickness of from about 6 to about 30 nm, and composed of from about 3 to about 10 molar % of a SrRuO₃conducting oxide dopant and from about 90 to about 97 molar % of a CaZrO₃insulating oxide material.
FILED	Thursday, April 26, 2007
APPL NO	11/740309
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Stock material or miscellaneous articles 428/697
VIEW PATENT	@ USPTO: Full Text PDF

07666594 — Methods for assaying a sample for an aggregant

US 07666594	Bazan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Singapore, Singapore)
ABSTRACT	This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.
FILED	Tuesday, January 31, 2006
APPL NO	11/344942
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

07666619 — Compounds and methods for regulating bacterial growth and pathogenesis

US 07666619	Bassler et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	Princeton University (Princeton, New Jersey); Quorex Pharmaceuticals, Inc. (Carlsbad, California); University Technologies International, Inc. (Calgary, Alberta, Canada)
INVENTOR(S)	Bonnie L. Bassler (Princeton, New Jersey); Stephan Schauder (Princeton, New Jersey); Kevan Shokat (San Francisco, California); Michael G. Surette (Calgary, Canada)
ABSTRACT	The invention provides autoinducer-2 analogs that regulate the activity of autoinducer-2 and methods of using such analogs for regulating bacterial growth and pathogenesis.
FILED	Wednesday, March 17, 2004
APPL NO	10/802425
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/32
VIEW PATENT	@ USPTO: Full Text PDF

07666708 — Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices

US 07666708	Lieber et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Charles M. Lieber (Lexington, Massachusetts); Yi Cui (Union City, California); Xiangfeng Duan (Mountain View, California); Yu Huang (Cambridge, Massachusetts)
ABSTRACT	A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal is, axis, has a largest cross-sectional dimension less than 500 nanometers, and a free-standing and bulk-doped semiconductor with at least one portion having a smallest width of less than 500 nanometers. At least one portion of such a semiconductor may a smallest width of less than 200 nanometers, or less than 150 nanometers, or less than 100 nanometers, or less than 80 nanometers, or less than 70 nanometers, or less than 60 nanometers, or less than 40 nanometers, or less than 20 nanometers, or less than 10 nanometers, or even less an 5 nanometers. Such a semiconductor may be doped during growth. Such a semiconductor may be part of a device, which may include any of a variety of devices and combinations thereof, and a variety assembling techniques may be used to fabricate devices from such a semiconductor.
FILED	Wednesday, October 04, 2006
APPL NO	11/543352
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/99
VIEW PATENT	@ USPTO: Full Text PDF

07666817 — Cellular libraries of peptide sequences (CLiPS) and methods of using the same

US 07666817	Daugherty et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Patrick Sean Daugherty (Santa Barbara, California); Kevin T. Boulware (Santa Barbara, California)
ABSTRACT	The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme.
FILED	Wednesday, August 30, 2006
APPL NO	11/514377
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Combinatorial chemistry technology: Method, library, apparatus 56/4
VIEW PATENT	@ USPTO: Full Text PDF

07666994 — Cloning and expression of gonadotropin-releasing hormone (GnRH) receptors

US 07666994	Sower et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S)	University of New Hampshire (Durham, New Hampshire)
INVENTOR(S)	Stacia Sower (Newmarket, New Hampshire); Nathaniel V. Nucci (Philadelphia, Pennsylvania); Matthew R. Silver (Rockport, Massachusetts)
ABSTRACT	An isolated and purified GnRH protein receptor protein including an amino acid sequence selected from the group and an isolated and purified DNA which comprises a nucleotide sequence coding for the GnRH protein receptor protein. Also, a vector comprising the DNA of the GnRH protein receptor protein, a transformant carrying the vector comprising the DNA of the GnRH protein receptor protein, a process for producing a GnRH protein receptor protein or a salt thereof including culturing the transformant carrying the vector comprising the DNA of the GnRH protein receptor protein under sufficient conditions and for appropriate time to express the GnRH protein receptor protein, and a method of screening for a ligand to the GnRH protein receptor protein including contacting the GnRH protein receptor protein or a salt thereof with a sample to be tested. A screening method for a compound capable of inhibiting binding of the GnRH protein receptor protein with a ligand. Also, a kit for screening a compound capable of inhibiting binding of the GnRH protein receptor protein with a ligand including the GnRH protein receptor protein or a salt.
FILED	Monday, December 01, 2008
APPL NO	12/315229
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350
VIEW PATENT	@ USPTO: Full Text PDF

07667077 — Poly-halogenated triazapentadiene compositions

US 07667077	Dias et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S)	Board of Regents, The University of Texas (Arlington, Texas)
INVENTOR(S)	H. V. Rasika Dias (Arlington, Texas); Lorraine G. Van Waasbergen (Arlington, Texas); Jaime A. Flores (Arlington, Texas)
ABSTRACT	A new class of fluorinated or polyhalogenated triazapentadienes are disclosed. The synthesized triazapentadienes are thermally stable, soluble in typical solvents and have several metal binding sites for complexation with metal ions. The compounds are prepared as colorless crystalline solids. Synthesis takes advantage of a reaction with triethylamine. Synthesized triazapentadienes (with and without complexed metals) inhibit bacterial growth of both Gram positive and Gram-negative bacteria.
FILED	Wednesday, September 12, 2007
APPL NO	11/853951
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Organic compounds 564/243
VIEW PATENT	@ USPTO: Full Text PDF

07667099 — Plastid division and related genes and proteins, and methods of use

US 07667099	Osteryoung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	Board of Trustees of Michigan State University (Lansing, Michigan)
INVENTOR(S)	Katherine W. Osteryoung (Williamston, Michigan); Stanislav Vitha (Haslett, Michigan); Olga A. Koksharova (Moscow, Russian Federation); Hongbo Gao (East Lansing, Michigan)
ABSTRACT	The present invention relates to genes encoding proteins involved in prokaryotic type or plastid division and/or morphology and the encoded proteins, and in particular to isolated Ftn2 (ARC6), ARC5, and Fzo-like genes and polypeptides. The present invention also provides methods for using Ftn2 (ARC6), ARC5, and Fzo-like genes, and polypeptides.
FILED	Friday, June 20, 2003
APPL NO	10/600070
ART UNIT	1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Multicellular living organisms and unmodified parts thereof and related processes 8/298
VIEW PATENT	@ USPTO: Full Text PDF

07667497 — Process variation tolerant circuit with voltage interpolation and variable latency

US 07667497	Liang et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Xiaoyao Liang (Cambridge, Massachusetts); David Brooks (Cambridge, Massachusetts); Gu-Yeon Wei (Cambridge, Massachusetts)
ABSTRACT	A circuit having dynamically controllable power. The circuit comprises a plurality of pipelined stages, each of the pipelined stages comprising two clocking domains, a plurality of switching circuits, each switching circuit being connected to one of the pipelined stages, first and second power sources connected to each of the plurality of pipelined stages through the switching circuits, the first power source supplying a first voltage and the second power source supplying a second voltage, wherein the first and second power sources each may be applied to a pipelined stage independently of other pipelined stages, first and second complementary clocks, and a plurality of latches connected to the first and second complementary clocks and to the plurality of pipelined stages for proving latch-based clocking to control the first and second clocking domains and to enable time-borrowing across the plurality of switching circuits. The first voltage differs from the second voltage and the plurality of pipelined stages interpolates between the first and second voltages to provide differing effective voltages between the first and second voltages.
FILED	Thursday, October 30, 2008
APPL NO	12/261771
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Electronic digital logic circuitry 326/93
VIEW PATENT	@ USPTO: Full Text PDF

07667832 — System for identifying refractive-index fluctuations of a target

US 07667832	Backman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois); NorthShore University HealthSystem (Evanston, Illinois)
INVENTOR(S)	Vadim Backman (Chicago, Illinois); Yang Liu (Somerset, New Jersey); Young Kim (West Lafayette, Indiana)
ABSTRACT	Systems and methods for identifying refractive-index fluctuations of a target are described in this application. One embodiment includes identifying one or more properties of emergent light, the emergent light to be emergent from a target, and determining refractive-index fluctuations of the target based on the one or more properties of the emergent light. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations.
FILED	Monday, August 13, 2007
APPL NO	11/891884
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/128
VIEW PATENT	@ USPTO: Full Text PDF

07668266 — Crest factor reduction in OFDM using blind selected pilot tone modulation

US 07668266	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Ning Chen (Atlanta, Georgia); Guotong Zhou (Atlanta, Georgia)
ABSTRACT	Orthogonal frequency division multiplexing (OFDM) is a spectrally efficient multicarrier modulation technique for high speed data transmission over multipath fading channels, but has low power efficiency. OFDM signals have large crest factors, or peak-to-average power ratios (PARs) which lead to power inefficiency in the RF portion of the transmitter. Selected mapping can be used to reduce the PAR of an OFDM signal and is distortionless. A technique is disclosed that links the index of a phase rotation sequence used in selected mapping to the location of pilot tones that are used to estimate the channel. Each pilot tone location-phase sequence selection produces a different PAR value for the time-domain OFDM signal, and the signal with the lowest PAR value is transmitted. The technique is “blind” in that the optimum pilot tone location-phase sequence index is not transmitted as side information. A technique to blindly detect the optimum index at the receiver is also disclosed.
FILED	Tuesday, March 14, 2006
APPL NO	11/374704
ART UNIT	2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Pulse or digital communications 375/347
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

07665891 — Differential temperature sensor system and method

US 07665891	Savchenkov et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Anatoliy A. Savchenkov (Glendale, California); Nan Yu (Arcadia, California); Lute Maleki (Pasadena, California); Vladimir S. Iltchenko (Arcadia, California); Andrey B. Matsko (Pasadena, California); Dmitry V. Strekalov (Arcadia, California)
ABSTRACT	A differential temperature sensor system and method of determining a temperature shift of an optical resonator and its surroundings are provided. The differential temperature sensor system includes a light generating device capable of generating a beam having a carrier frequency, a modulator capable of modulating the beam with a sideband frequency, and an optical resonator capable of supporting an ordinary mode and an extraordinary mode. The system includes an ordinary mode-lock setup capable of locking the carrier frequency of the beam to the ordinary mode of the optical resonator and an extraordinary mode-lock setup capable of locking the sideband frequency of the beam to the extraordinary mode of the optical resonator by providing a specific radio frequency to the modulator substantially corresponding to a frequency shift between the ordinary mode and the extraordinary mode of the optical resonator resulting from a temperature change of the optical resonator. A processor precisely calculates the differential temperature based upon the frequency shift between the ordinary mode and extraordinary mode of the optical resonator.
FILED	Thursday, September 20, 2007
APPL NO	11/858318
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Thermal measuring and testing 374/117
VIEW PATENT	@ USPTO: Full Text PDF

07666259 — Screening and crystallization plates for manual and high-throughput protein crystal growth

US 07666259	Thorne et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S)	Robert E. Thorne (Ithaca, New York); Viatcheslav Berejnov (Ithaca, New York); Yevgeniy Kalinin (Ithaca, New York)
ABSTRACT	In one embodiment, a crystallization and screening plate comprises a plurality of cells open at a top and a bottom, a frame that defines the cells in the plate, and at least two films. The first film seals a top of the plate and the second film seals a bottom of the plate. At least one of the films is patterned to strongly pin the contact lines of drops dispensed onto it, fixing their position and shape. The present invention also includes methods and other devices for manual and high-throughput protein crystal growth.
FILED	Tuesday, August 08, 2006
APPL NO	11/463033
ART UNIT	1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/68
VIEW PATENT	@ USPTO: Full Text PDF

07666512 — Thermal resistant environmental barrier coating

US 07666512	Bhatia et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Tania Bhatia (Middletown, Connecticut); Harry Eaton (Woodstock, Connecticut); Ellen Y. Sun (South Windsor, Connecticut); Thomas H. Lawton (Wethersfield, Connecticut)
ABSTRACT	A process for preparing a silicon based substrate with a protective coating having improved thermal resistance at temperature up to at least 1500° C., and the resulting article.
FILED	Monday, August 09, 2004
APPL NO	10/915158
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Stock material or miscellaneous articles 428/446
VIEW PATENT	@ USPTO: Full Text PDF

07666939 — Dispersions of carbon nanotubes in polymer matrices

US 07666939	Wise et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	National Institute of Aerospace Associates (Hampton, Virginia); The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	Kristopher Eric Wise (Hampton, Virginia); Cheol Park (Yorktown, Virginia); Emilie J. Siochi (Newport News, Virginia); Joycelyn S. Harrison (Hampton, Virginia); Peter T. Lillehei (Yorktown, Virginia); Sharon E. Lowther (Hampton, Virginia)
ABSTRACT	Dispersions of carbon nanotubes exhibiting long term stability are based on a polymer matrix having moieties therein which are capable of a donor-acceptor complexation with carbon nanotubes. The carbon nanotubes are introduced into the polymer matrix and separated therein by standard means. Nanocomposites produced from these dispersions are useful in the fabrication of structures, e.g., lightweight aerospace structures.
FILED	Thursday, May 11, 2006
APPL NO	11/432201
ART UNIT	1796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Synthetic resins or natural rubbers 524/495
VIEW PATENT	@ USPTO: Full Text PDF

07667418 — Control system for bearingless motor-generator

US 07667418	Kascak et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	The University of Toledo (Toledo, Ohio)
INVENTOR(S)	Peter E. Kascak (Westlake, Ohio); Ralph H. Jansen (Grafton, Ohio); Timothy P. Dever (Westlake, Ohio)
ABSTRACT	A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.
FILED	Thursday, October 30, 2008
APPL NO	12/261707
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Motive power systems 318/400.20
VIEW PATENT	@ USPTO: Full Text PDF

07667847 — Photogrammetric system and method used in the characterization of a structure

US 07667847	Dorrington et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Adrian A. Dorrington (Hamilton, New Zealand); Thomas W. Jones (Smithfield, Virginia); Paul M. Danehy (Newport News, Virginia); Kent A. Watson (New Kent, Virginia); John W. Connell (Yorktown, Virginia); Richard S. Pappa (Newport News, Virginia); W. Keith Belvin (Wicomico, Virginia)
ABSTRACT	A photogrammetric system uses an array of spaced-apart targets coupled to a structure. Each target exhibits fluorescence when exposed to a broad beam of illumination. A photogrammetric imaging system located remotely with respect to the structure detects and processes the fluorescence (but not the illumination wavelength) to measure the shape of a structure.
FILED	Thursday, September 21, 2006
APPL NO	11/533921
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/445
VIEW PATENT	@ USPTO: Full Text PDF

07668796 — Automata learning algorithms and processes for providing more complete systems requirements specification by scenario generation, CSP-based syntax-oriented model construction, and R2D2C system requirements transformation

US 07668796	Hinchey et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Michael G. Hinchey (Bowie, Maryland); Tiziana Margaria (Dortmund, Germany); James L. Rash (Davidsonville, Maryland); Christopher A. Rouff (Beltsville, Maryland); Bernard Steffen (Dortmund, Germany)
ABSTRACT	Systems, methods and apparatus are provided through which in some embodiments, automata learning algorithms and techniques are implemented to generate a more complete set of scenarios for requirements based programming. More specifically, a CSP-based, syntax-oriented model construction, which requires the support of a theorem prover, is complemented by model extrapolation, via automata learning. This may support the systematic completion of the requirements, the nature of the requirement being partial, which provides focus on the most prominent scenarios. This may generalize requirement skeletons by extrapolation and may indicate by way of automatically generated traces where the requirement specification is too loose and additional information is required.
FILED	Thursday, September 28, 2006
APPL NO	11/536132
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/48
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

07666499 — High modulus polyamide fibers

US 07666499	Jung et al.
FUNDED BY	Department of Commerce (DOC) National Textile Center (NTC)
APPLICANT(S)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Dongwook Jung (Raleigh, North Carolina); Richard Kotek (Raleigh, North Carolina); Alan E. Tonelli (Cary, North Carolina); Nadarajah Vasanthan (Princeton, New Jersey)
ABSTRACT	A process for preparing high initial modulus and high tensile strength polyamide fibers is described. The process comprises complexing the polyamide with a Lewis acid, dry-jet wet spinning the complexed fibers, drying the spun fibers for a period of time, drawing the fibers, and soaking the fibers in solvent to remove the Lewis acid. High molecular weight nylon 6,6 fibers prepared according to the described process show initial moduli of up to 30.1 GPa and tenacities of up to 2.5 GPa.
FILED	Wednesday, September 27, 2006
APPL NO	11/528701
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Stock material or miscellaneous articles 428/364
VIEW PATENT	@ USPTO: Full Text PDF

07667157 — Portable plenum laser forming

US 07667157	Zhang et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S)	General Electric Company (Niskayuna, New York)
INVENTOR(S)	Wenwu Zhang (Schenectady, New York); Marshall Gordon Jones (Scotia, New York); Brian Harlow Farrell (Amsterdam, New York)
ABSTRACT	A laser forming system includes a motion system. A mounting fixture is affixed to the motion system for supporting a workpiece. A plenum is affixed to the fixture for surrounding the workpiece. A gas supply is joined in flow communication with the plenum for channeling thereto an inert gas under pressure to fill the plenum. A laser is aligned with the plenum for projecting a laser beam at the workpiece for laser forming thereof inside the plenum.
FILED	Thursday, March 24, 2005
APPL NO	11/089750
ART UNIT	3742 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Electric heating 219/121.630
VIEW PATENT	@ USPTO: Full Text PDF

07668787 — Method, apparatus, and program product for efficiently adding entities and relationships in a comprehension state of a collection of information

US 07668787	Bier
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Advanced Research and Development Activity (ARDA)
APPLICANT(S)
ASSIGNEE(S)	Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S)	Eric A Bier (Palo Alto, California)
ABSTRACT	Aspects of the disclosed technology present a workspace window responsive to a relationship data structure that represents a comprehension state including a presentation set of an ordered set of text strings from an electronic document. The presentation set includes one or more identified strings. The workspace window can then receive a quick-click command invocation on the one or more identified strings and modifies the relationship data structure by adding an entity/relationship object to the relationship data structure responsive to the quick-click command invocation and the one or more identified strings. The application relates to sensemaking or maintaining a comprehension state of a document collection, by recording evidence, spatial hypertext, automatic highlighting, automating inferencing, reading recommendations, and reading through multiple documents.
FILED	Tuesday, June 27, 2006
APPL NO	11/426915
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/11
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

07666438 — Multicomponent vaccines

US 07666438	Patti et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S)	Inhibitex, Inc. (Alpharetta, Georgia); The Provost Fellows and Scholars of the College of the Holy and Undivived Trinity of Queen Elizabeth Near Dublin (Dublin, Ireland); The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Joseph M. Patti (Cumming, Georgia); Timothy J. Foster (Dublin, Ireland); Magnus Hook (Houston, Texas)
ABSTRACT	Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful selection of the proteins, fragments, or antibodies, a vaccine is provided that imparts protection against a broad spectrum of Staphylococcus and other bacterial strains and against proteins that are expressed at different stages of the logarithmic growth curve. In one embodiment of the invention, a composition is provided that includes a fibrinogen binding domain of a fibrinogen binding protein and a bacterial component such as ca capsular polysaccharide, and both active and passive vaccines based on these components are also provided, along with methods of treating infection using these compositions and vaccines.
FILED	Tuesday, March 09, 2004
APPL NO	10/795267
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/243.100
VIEW PATENT	@ USPTO: Full Text PDF

07666590 — Identification of fat and lean phenotypes in chickens using molecular markers

US 07666590	Cogburn et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S)	University of Delaware (Newark, Delaware)
INVENTOR(S)	Larry A. Cogburn (New London, Pennsylvania); Wilfrid G. Carre (Edinburgh, United Kingdom); Xiaofei Wang (Nashville, Tennessee)
ABSTRACT	The present invention provides methods of screening chickens to determine those more likely to have a lean or fat phenotype. The invention also provides methods of screening chickens to identify a polymorphism associated with a fat or lean phenotype.
FILED	Thursday, December 16, 2004
APPL NO	11/013546
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

07667142 — Lightweight circuit board with conductive constraining cores

US 07667142	Vasoya et al.
FUNDED BY	Department of Transportation (USDOT) Federal Aviation Administration (FAA) National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S)	Stablcor, Inc. (Costa Mesa, California)
INVENTOR(S)	Kalu K. Vasoya (Santa Ana, California); Bharat M. Mangrolia (Santa Ana, California); William E. Davis (Huntington Beach, California); Richard A. Bohner (Hermosa Beach, California)
ABSTRACT	Prepregs, laminates, printed wiring board structures and processes for constructing materials and printed wiring boards that enable the construction of printed wiring boards with improved thermal properties. In one embodiment, the prepregs include substrates impregnated with electrically and thermally conductive resins. In other embodiments, the prepregs have substrate materials that include carbon. In other embodiments, the prepregs include substrates impregnated with thermally conductive resins. In other embodiments, the printed wiring board structures include electrically and thermally conductive laminates that can act as ground and/or power planes.
FILED	Wednesday, August 18, 2004
APPL NO	10/921616
ART UNIT	1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Electricity: Conductors and insulators 174/255
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

07666249 — Linear hearth furnace system and methods regarding same

US 07666249	Bleifuss et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)	Nu-Iron Technology, LLC (Charlotte, North Carolina)
INVENTOR(S)	Rodney L. Bleifuss (Grand Rapids, Minnesota); David J. Englund (Bovey, Minnesota); Richard F. Kiesel (Hibbing, Minnesota)
ABSTRACT	Systems and methods for use in processing raw material (e.g., iron bearing material) include a linear furnace apparatus extending along a longitudinal axis between a charging end and a discharging end (e.g., the linear furnace apparatus includes at least a furnace zone positioned along the longitudinal axis). Raw material is provided into one or more separate or separable containers (e.g., trays) at the charging end of the linear furnace apparatus. The separate or separable containers are moved through at least the furnace zone and to the discharging end where the processed material is discharged resulting in one or more empty containers. One or more of the empty containers are returned to the charging end of the linear furnace apparatus to receive further raw material.
FILED	Tuesday, August 19, 2008
APPL NO	12/194303
ART UNIT	1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/484
VIEW PATENT	@ USPTO: Full Text PDF

07666282 — Process for providing ethanol

US 07666282	Sylvester et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)	E.I. du Pont de Nemours and Company (Wilmington, Delaware)
INVENTOR(S)	Robert G. Sylvester (Newark, Delaware); Stephen Thomas Breske (Wilmington, Delaware); David A. Culver (Salem, New Jersey); Bruce M. Vrana (Hockessin, Delaware)
ABSTRACT	The invention is a process for the purification of ethanol. In one embodiment the process includes boiling a degassed beer feed (106) in a pre-boiler (110) to provide a vapor by-pass fraction (112) that by-passes the conventional beer column and is fed into the rectifier column (124). The process allows free capacity in the rectifier column of new or established plants to be filled by ethanol-water vapor and/or condensate streams that do not originate from the beer column.
FILED	Wednesday, December 28, 2005
APPL NO	11/320206
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Distillation: Processes, separatory 23/19
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

What You'll Find On This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, February 23, 2010.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100223.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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