FedInvent™ Patents
Patent Details for Tuesday, May 25, 2010
This page was updated on Monday, March 27, 2023 at 01:50 AM GMT
Department of Health and Human Services (HHS)
| US 07722565 | Wood et al. |
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| ASSIGNEE(S) | Traxtal, Inc. (Toronto, Ontario, Canada); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Bradford Johns Wood (Potomac, Maryland); Neil David Glossop (Toronto, Canada) |
| ABSTRACT | The invention provides systems and methods for providing access to a target site. Example systems may include a needle, a grid to guide the needle, a plate with an aperture, a member coupled to the plate and including a semispherical surface, and a hub slideably coupled to the plate by a guide. The system may also include a needle coupled to the hub, the needle including a magnetically trackable sensor positioned in a tip of the needle. The semispherical surface can be positioned against skin of a body and the hub slid relative to the plate along the guide to insert the needle through the aperture in the plate into the body until the tip reaches a target site. The hub can be locked by a lock mechanism when the tip of the needle reaches the target site, and an action performed on the target site through the needle. |
| FILED | Friday, November 04, 2005 |
| APPL NO | 11/718679 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722860 | Kappe et al. |
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| ASSIGNEE(S) | Seattle Biomedical Research Institute (Seattle, Washington) |
| INVENTOR(S) | Stefan H. I. Kappe (Seattle, Washington); Kai-Uwe C. Matuschewski (Berlin, Germany); Ann-Kristin Mueller (Dossenheim, Germany) |
| ABSTRACT | The invention provides methods for inducing an immune response in a vertebrate host against a protozoan parasite, comprising administering to the host a live protozoan parasite that is genetically engineered to disrupt a stage-specific gene function that is required by the protozoan parasite to establish a secondary infection in the vertebrate host. Representative protozoan parasites belong to the phyla Apicomplexa and Kinetoplastida. The vertebrate host may be a mammal or a bird. |
| FILED | Wednesday, June 22, 2005 |
| APPL NO | 11/165586 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722861 | Jacobs et al. |
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| INVENTOR(S) | William R. Jacobs (Pelham, New York); Tsungda Hsu (Bronx, New York); Stoyan Bardarov (Bronx, New York); Svetoslav Bardarov, legal representative (Worcester, Massachusetts); Vasan Sambandamurthy (Bronx, New York) |
| ABSTRACT | Non-naturally occurring mycobacteria in the Mycobacterium tuberculosis complex are provided. These mycobacteria have a deletion of an RD1 region or a region controlling production of a vitamin, and exhibit attenuated virulence in a mammal when compared to the mycobacteria without the deletion. Also provided are non-naturally occurring mycobacteria that have a deletion of a region controlling production of lysine, and mycobacteria comprising two attenuating deletions. Vaccines comprising these mycobacteria are also provided, as are methods of protecting mammals from virulent mycobacteria using the vaccines. Also provided are methods of preparing these vaccines which include the step of deleting an RD1 region or a region controlling production of a vitamin from a mycobacterium in the M. tuberculosis complex. |
| FILED | Friday, January 24, 2003 |
| APPL NO | 10/351452 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722862 | Bluestone et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey A. Bluestone (San Francisco, California); Qizhi Tang (San Francisco, California); Emma Masteller (San Francisco, California) |
| ABSTRACT | The invention provides methods for producing an autoantigen-specific regulatory T cell enriched composition, and resultant compositions and methods of use. |
| FILED | Thursday, June 22, 2006 |
| APPL NO | 11/473959 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.710 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722868 | Freeman et al. |
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| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Brigham and Women's Hospital (Boston, Massachusetts) |
| INVENTOR(S) | Gordon J. Freeman (Brookline, Massachusetts); Arlene H. Sharpe (Brookline, Massachusetts); Janet Buhlman (Allston, Massachusetts); Didier Mandelbrot (Newton, Massachusetts) |
| ABSTRACT | Disclosed are methods for modulating an immune response including a method for inhibiting the interaction between a B7 polypeptide and a PD-1 ligand, the method comprising contacting an immune cell bearing a PD-1 ligand, or an immune cell bearing a B7 polypeptide, with an agent that inhibits the interaction between the PD-1 ligand and the B7 polypeptide. Such agents may be an anti-PD-1 ligand antibody or a small molecule. Also disclosed is a method for modulating an immune response comprising contacting an immune cell bearing the PD-1 ligand, or an immune cell bearing the PD-1 polypeptide, with an agent that inhibits interactions between the PD-1 ligand and the PD-1 polypeptide, without inhibiting interactions between the PD-1 ligand and a B7 polypeptide, to thereby modulate an immune response. The agent may be an anti-PD-1 ligand antibody or a small molecule. |
| FILED | Wednesday, August 09, 2006 |
| APPL NO | 11/501392 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722894 | Wang et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yadong Wang (Somerville, Massachusetts); Guillermo Ameer (Chicago, Illinois); Robert Langer (Newton, Massachusetts) |
| ABSTRACT | A biodegradable polymer comprising a condensation polymer of glycerol and a diacid. The polymer may be adapted for use as a tissue engineering construct. For example, it may be seeded with cells or molecules may be attached to it to modify the metabolism and proliferation of cells or to modify the degradation rate and/or mechanism of the polymer. The polymer may also be exploited in a variety of medical and non-medical applications. |
| FILED | Monday, October 21, 2002 |
| APPL NO | 10/277562 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723021 | Greene et al. |
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| ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Warner C. Greene (Hillsborough, California); Kimberly S. Stopak (San Francisco, California); Carlos M. deNoronha (Hillsborough Court, California); Ya-Lin Chiu (San Francisco, California); Vanessa B. Soros (San Francisco, California); Wesley M. Yonemoto (San Francisco, California) |
| ABSTRACT | The present invention provides methods of identifying an agent that inhibits an activity of a lentiviral Vif protein. The present invention provides methods of identifying an agent that increases the level of active APOBEC3G in a cell. The present invention provides agents identified by a subject screening method; and further provides methods for treating lentivirus infections. |
| FILED | Tuesday, February 06, 2007 |
| APPL NO | 11/671991 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723022 | Krieg et al. |
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| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); Coley Pharmaceutical Group, Inc. (New York, New York); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Arthur M. Krieg (Wellesley, Massachusetts); Dennis Klinman (Potomac, Maryland); Alfred D. Steinberg (Potomac, Maryland) |
| ABSTRACT | Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/036527 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723023 | Sealfon et al. |
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| ASSIGNEE(S) | Mount Sinai School of Medicine (New York, New York) |
| INVENTOR(S) | Stuart Sealfon (Brooklyn, New York); Elisa Wurmbach (New York, New York); Tony Yuen (New York, New York) |
| ABSTRACT | The present invention identifies essentially all of the members of a specific group of genes that are preferentially transcribed upon the initialization of a signal transduction pathway. The present invention also discloses methods for detecting and/or quantifying the transcription of these specific genes. The present invention further discloses methods of using this information to characterize the effect of potential drugs on a cell. Solid supports comprising nucleic acids that can hybridize with the transcripts from this specific group of genes are also described. |
| FILED | Wednesday, August 14, 2002 |
| APPL NO | 10/218969 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723030 | Croce et al. |
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| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Carlo M. Croce (Columbus, Ohio); Chang-Gong Liu (Powell, Ohio); George A. Calin (Columbus, Ohio); Cinzia Sevignani (Philadelphia, Pennsylvania) |
| ABSTRACT | MicroRNA genes are highly associated with chromosomal features involved in the etiology of different cancers. The perturbations in the genomic structure or chromosomal architecture of a cell caused by these cancer-associated chromosomal features can affect the expression of the miR gene(s) located in close proximity to that chromosomal feature. Evaluation of miR gene expression can therefore be used to indicate the presence of a cancer-causing chromosomal lesion in a subject. As the change in miR gene expression level caused by a cancer-associated chromosomal feature may also contribute to cancerigenesis, a given cancer can be treated by restoring the level of miR gene expression to normal. microRNA expression profiling can be used to diagnose cancer and predict whether a particular cancer is associated with an adverse prognosis. The identification of specific mutations associated with genomic regions that harbor miR genes in CLL patients provides a means for diagnosing CLL and possibly other cancers. |
| FILED | Friday, July 29, 2005 |
| APPL NO | 11/194055 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723031 | Benkovic et al. |
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| ASSIGNEE(S) | ThePenn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J. Benkovic (State College, Pennsylvania); Frank Salinas (Wheaton, Illinois) |
| ABSTRACT | A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. |
| FILED | Monday, August 15, 2005 |
| APPL NO | 11/204125 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723035 | Croce et al. |
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| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Carlo Croce (Philadelphia, Pennsylvania); George Calin (Philadelphia, Pennsylvania) |
| ABSTRACT | The miR15 and miR16 micro RNA genes are located at 13q14 within a 30 kb region of loss characteristic of cells from certain cancers, such as cells from chronic lymphocytic leukemia or prostate cancer. Chronic lymphocytic leukemia or prostate cancer can be diagnosed by detecting a reduction in miR15 or miR16 gene copy number, by determining miR15 or miR16 gene mutational status, or by detecting a reduction in the RNA transcribed from these genes. The miR15 or miR16 gene products can inhibit the neoplastic or tumorigenic growth of cancers such as chronic lymphocytic leukemia or prostate cancer cells when administered to subjects suffering from these diseases. |
| FILED | Monday, March 13, 2006 |
| APPL NO | 11/375650 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723036 | Racila et al. |
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| ASSIGNEE(S) | The University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Emilian V. Racila (North Liberty, Iowa); George J. Weiner (Iowa City, Iowa) |
| ABSTRACT | The present invention encompasses methods for predicting metastasis in cancer by assessing the structure of the complement protein C1qA. The methods may encompass examining either protein or nucleic acids, and may further include making treatment decisions based on the predictive methods. |
| FILED | Thursday, August 17, 2006 |
| APPL NO | 11/505635 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07723037 — Methods and kits for diagnosing or monitoring autoimmune and chronic inflammatory disease
| US 07723037 | Richardson et al. |
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| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Bruce Richardson (Ann Arbor, Michigan); Qianjin Lu (Changsha, China PRC) |
| ABSTRACT | The present invention relates to compositions and methods for diagnosing, monitoring and/or treating an autoimmune or chronic inflammatory disease. In particular, the present invention provides methods for diagnosing, monitoring and treating an autoimmune disease (e.g., rheumatoid arthritis) or chronic inflammatory disease (e.g., systemic lupus erythematosus) based on detecting or altering (e.g., altering expression or methylation status of) autoimmune or chronic inflammatory disease proteins (e.g., CD70 and CD40L). The present invention also provides kits for detecting methylation status of autoimmune or chronic inflammatory disease proteins (e.g., CD70 and CD40L) and for diagnosing, monitoring and/or treating autoimmune or chronic inflammatory diseases. |
| FILED | Thursday, September 06, 2007 |
| APPL NO | 11/850897 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723040 | Bee et al. |
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| ASSIGNEE(S) | Gen-Probe Incorporated (San Diego, California) |
| INVENTOR(S) | Gary G. Bee (Vista, California); Yeasing Y. Yang (San Diego, California); Dan Kolk (Ramona, California); Cristina Giachetti (Solana Beach, California); Sherrol H. McDonough (San Diego, California) |
| ABSTRACT | Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed. |
| FILED | Thursday, September 04, 2008 |
| APPL NO | 12/204742 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723045 | Fogelman et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alan M. Fogelman (Beverly Hills, California); Srinivasa T. Reddy (Cerritos, California) |
| ABSTRACT | This invention provides novel assays for the detection of dysfunctional HDL. The assays are good diagnostics and/or prognostics for atherosclerosis or other pathologies characterized by an inflammatory response. In certain embodiments the methods involve measurements of heme-related HDL-associated proteins (e.g., haptoglobin, hemopexin, etc.), and/or measurements of the relative distribution of HDL-associated proteins between HDL and the non-lipoprotein fractions of plasma/serum, and/or measurements of the ability of pro-inflammatory HDL to consume nitric oxide, and/or measurement of the ability of HDL to inhibit LDL aggregation. |
| FILED | Thursday, February 08, 2007 |
| APPL NO | 11/672897 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723054 | Latz et al. |
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| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Eicke Latz (Boston, Massachusetts); Alberto Visintin (Worcester, Massachusetts); Douglas T. Golenbock (Wellesley, Massachusetts) |
| ABSTRACT | TLR9 is localized to endoplasmic reticulum and upon stimulation with a TLR9 ligand, is transported to a tubular lysosomal compartment as is CpG-DNA. Furthermore, it is shown that TLR9 and CpG-DNA directly bind. It was also found that the MyD88 translocates in response to activation of TLR9-mediated signaling. Methods of identifying compounds that affect translocation and activity of TLR9 and MyD88 are described. |
| FILED | Thursday, January 26, 2006 |
| APPL NO | 11/341319 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723057 | Snow |
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| ASSIGNEE(S) | Proteotech, Inc. (Kirkland, Washington) |
| INVENTOR(S) | Alan D. Snow (Lynnwood, Washington) |
| ABSTRACT | A screening assay for selecting macromolecules that interfere with the binding of a sulfated GAG to beta amyloid, the assay comprising affixing a sulfated GAG to a substrate, co-incubating the macromolecule and a known amount of beta amyloid with the sulfated GAG, determining the amount of beta amyloid bound to the sulfated GAG affixed to the substrate; wherein the macromolecule will be one which interferes with the binding of the sulfated GAG to beta amyloid. |
| FILED | Tuesday, March 30, 1999 |
| APPL NO | 10/536111 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.910 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723069 | Soll et al. |
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| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Dieter Soll (Hamden, Connecticut); Jesse Rinehart (New Haven, Connecticut) |
| ABSTRACT | Nucleic acids encoding genes with SepRS and tRNASep activity for site specific incorporation of phosphoserine into a protein or polypeptide and methods of use thereof are described. Typically, SepRS preferentially aminoacylates tRNASep with O-phosphoserine and the tRNASep recognizes at least one codon such as a stop codon. In a preferred embodiment the nucleic acids are on vectors. In one embodiment, the vectors are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. In an alternative embodiment, the vectors are expressed in an in vitro transcription/translation system. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery. |
| FILED | Monday, April 03, 2006 |
| APPL NO | 11/396439 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723075 | Penner et al. |
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| ASSIGNEE(S) | The Queens's Medical Center (Honolulu, Hawaii) |
| INVENTOR(S) | Reinhold Penner (Honolulu, Hawaii); Andrea Flieg (Honolulu, Hawaii) |
| ABSTRACT | The invention relates to methods useful in identifying molecules that bind TRPM5, which modulate TRPM5 ion channel activity, and/or which alter expression of TRPM5 within cells. The TRPM5 channels as described herein contain TRPM5 polypeptides, which are in turn encoded by TRPM5 nucleic acids. The ion channels described herein are preferably formed in HEK-293 cells from one or more novel TRPM5 polypeptides, which exhibit one or more of the unique TRPM5 properties described herein. |
| FILED | Monday, February 23, 2004 |
| APPL NO | 10/785758 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/70.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723087 | Pier et al. |
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| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Kimberly Jefferson (Dedham, Massachusetts) |
| ABSTRACT | The invention relates to nucleic acid sequences and related compositions for producing over-expression of the polysaccharide PNAG of Staphylococci. PNAG may be isolated and formulated into vaccines or used to generate antibodies. Binding agents of the nucleic acids are also described. The invention also relates to diagnostic and therapeutic methods using the compositions. |
| FILED | Wednesday, November 12, 2003 |
| APPL NO | 10/712391 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723089 | Williams et al. |
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| ASSIGNEE(S) | Mountain View Pharmaceuticals, Inc. (Menlo Park, California); Duke University (Durham, North Carolina) |
| INVENTOR(S) | L. David Williams (Fremont, California); Michael S. Hershfield (Durham, North Carolina); Susan J. Kelly (Chapel Hill, North Carolina); Mark G. P. Saifer (San Carlos, California); Merry R. Sherman (San Carlos, California) |
| ABSTRACT | A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. |
| FILED | Thursday, April 19, 2001 |
| APPL NO | 09/839946 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/190 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723094 | Kawaoka et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Stefan Hamm (River Vale, New Jersey); Hideki Ebihara (Winnipeg, Canada) |
| ABSTRACT | The invention provides a composition useful to prepare influenza viruses, e.g., in the absence of helper virus, using vectors which include PolII promoters and multiple ribozyme sequences. |
| FILED | Thursday, May 27, 2004 |
| APPL NO | 10/855975 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/239 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723096 | Schlom et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Elene Barzaga (Gaithersburg, Maryland); Sam Zaremba (Rockville, Maryland) |
| ABSTRACT | A nucleic acid molecule encoding an amino acid sequence consisting of an agonist of a MHC class I binding native sequence of CEA having an amino acid substitution and enhanced immunogenicity compared to the native sequence is described. A vector comprising the nucleic acid molecule, host cell comprising the vector and a kit comprising the encoded agonist peptide are also described. |
| FILED | Wednesday, December 03, 2003 |
| APPL NO | 10/725373 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723103 | Mead et al. |
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| ASSIGNEE(S) | Lucigen Corporation (, Wisconsin) |
| INVENTOR(S) | David A. Mead (Middleton, Wisconsin); Ronald Godiska (Verona, Wisconsin); Thomas W. Schoenfeld (Madison, Wisconsin); Spencer Hermanson (Watertown, Wisconsin) |
| ABSTRACT | Vector preparations and cloning constructs suitable for use in cloning are provided. Vector preparations are double-stranded DNA molecules having two 3′ termini, each terminus having a single base pair overhang that is capable of hybridizing to a single base pair overhang on a double stranded polynucleotide sequence to be cloned. The overhang of the vector preparation is suitably a dCMP and the overhang of the polynucleotide sequence to be cloned is suitably a dGMP. In other embodiments, the overhang of the polynucleotide sequence to be cloned is any ddNTP and the corresponding overhang of the vector preparation is any base that pairs to the ddNTP. The latter embodiment is particularly suited to preparing recombinant molecules having only a single insert. Methods of cloning, methods of preparing libraries of recombinant molecules and kits for carrying out the methods are also provided. |
| FILED | Monday, January 08, 2007 |
| APPL NO | 11/621031 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723111 | Hwu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Patrick Hwu (Potomac, Maryland); Michael H. Kershaw (Rockville, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The present invention relates to preventive, therapeutic, and diagnostic compositions and methods employing lymphocytes having T-cell receptors and chimeric receptors. In particular, the invention relates to pre-selected dual-specificity lymphocytes having endogenous T-cell receptors and chimeric T-cell receptors that recognize a strong antigen and tumor associated antigens where the pre-selected population of adoptively transferred lymphocytes is activated by in vivo immunization, thereby increasing the effectiveness of adoptive immunotherapy. |
| FILED | Friday, March 09, 2001 |
| APPL NO | 09/803578 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723112 | Clarke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); OncoMed Pharmaceuticals, Inc. (Redwood City, California) |
| INVENTOR(S) | Michael F. Clarke (Palo Alto, California); Tim Hoey (Hillsborough, California); Xinhao Wang (Freemont, California); Scott Dylla (Mountain View, California); Austin Gurney (San Francisco, California); Piero Dalerba (Palo Alto, California); Mark Prince (Ann Arbor, Michigan); Grace Chen (Howell, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for characterizing, treating and diagnosing cancer. In particular, the present invention provides a cancer stem cell profile, as well as novel stem cell cancer markers useful for the diagnosis, characterization, prognosis and treatment of cancer and in particular the targeting of solid tumor stem cells. |
| FILED | Tuesday, October 31, 2006 |
| APPL NO | 11/591019 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/971 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723300 | Peluso |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | John J. Peluso (Avon, Connecticut) |
| ABSTRACT | A progesterone regulator capable of modulating the non-genomic action of progesterone and methods of using the progesterone regulator are described. The progesterone regulator is useful for attenuating progesterone's inhibition of apoptosis and for the treatment of patients having a progesterone-responsive tissue disease such as endometriosis or cancer, particularly ovarian cancer. |
| FILED | Wednesday, April 04, 2007 |
| APPL NO | 11/732780 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723301 | Shaughnessy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | John D. Shaughnessy (Little Rock, Arkansas); Uli Ruther (Dusseldorf, Germany); Jurgen Knobloch (Cologne, Germany) |
| ABSTRACT | Pharmaceutical compositions comprising anti-teratogenic agents are disclosed. Additionally, pharmaceutical compositions comprising anti-neoplastic agents and anti-teratogenic agents are disclosed. Methods of assessing the teratogenicity of a compound are disclosed. The present invention further comprises applications of the aforementioned compositions and methods. |
| FILED | Wednesday, August 29, 2007 |
| APPL NO | 11/846854 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723303 | Fogelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Alan M. Fogelman (Beverly Hills, California); Mohamad Navab (Los Angeles, California); Gattadahalli M. Anantharamaiah (Birmingham, Alabama) |
| ABSTRACT | This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The agents are highly stable and readily administered via an oral route. |
| FILED | Tuesday, April 18, 2006 |
| APPL NO | 11/407390 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723313 | Bouck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Chicago, Illinois) |
| INVENTOR(S) | Noel P. Bouck (Occidental, California); David W. Dawson (Los Angeles, California); Paul R. Gillis (San Francisco, California); Olga Volpert (Wilmette, Illinois); Susan E. Crawford (Burr Ridge, Illinois); Veronica M. Stellmach (Chicago, Illinois) |
| ABSTRACT | The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous PEDF to cells associated with the tissue. The presence of exogenous PEDF inhibits angiogenesis within the tissue, in part by interfering with the ability of vascular endothelia to expand within the tissue. The invention also provides a method for determining the severity of a tumor be assaying for the presence of PEDF within the tumor. To facilitate the inventive methods, the present invention provides pharmaceutical compositions including sources of PEDF. |
| FILED | Wednesday, July 26, 2006 |
| APPL NO | 11/494363 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723328 | Longo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ABSTRACT | Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75NTR receptor molecule. Enhanced survival of neural and other cells has been observed. |
| FILED | Monday, April 03, 2006 |
| APPL NO | 11/396936 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/231.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723375 | Powis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona Board of Regents, acting on behalf of The University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Garth Powis (Houston, Texas) |
| ABSTRACT | Novel metabolites of wortmannin and wortmannin analogs and their use in inhibiting PI-3 kinase activity in mammals and the treatment and prevention of cancer or tumor formation in a subject are described herein. |
| FILED | Friday, December 29, 2006 |
| APPL NO | 11/618036 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723467 | Lipkowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New England Medical Center Hospitals, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Andrzej W. Lipkowski (Warsaw, Poland); Daniel B. Carr (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions. |
| FILED | Wednesday, July 13, 2005 |
| APPL NO | 11/180971 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723472 | Szoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Francis C. Szoka (San Francisco, California); Joshua I. Park (San Francisco, California); Robert Stull (Alameda, California) |
| ABSTRACT | The present invention provides chimeric polypeptides comprising a first polypeptide that binds to a component of extracellular matrix and a second polypeptide that provides for a therapeutic effect. The present invention further provides compositions, including pharmaceutical compositions, comprising a subject chimeric polypeptide. A subject chimeric polypeptide is useful in a variety of treatment, diagnostic, and research applications, which are also provided. |
| FILED | Tuesday, February 28, 2006 |
| APPL NO | 11/365073 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723473 | Huang |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | St. Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Jung San Huang (St. Louis, Missouri) |
| ABSTRACT | This invention is drawn to methods of using peptide-based antagonists of TGF-beta to facilitate the healing of cutaneous wounds that includes burns, lacerations and scrapes. The administration of peptide TGF-beta antagonists to wounds results in reduced scarring, wound contraction and deposition of extracellular matrix components, and increased rates of re-epithelialization during wound healing. |
| FILED | Thursday, May 11, 2006 |
| APPL NO | 11/432125 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723474 | Hanahan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Burnham Institute for Medical Research (La Jolla, California) |
| INVENTOR(S) | Douglas Hanahan (San Francisco, California); Erkki Ruoslahti (Rancho Santa Fe, California) |
| ABSTRACT | The present invention provides a conjugate that contains a therapeutic moiety linked to a homing peptide or peptidomimetic which selectively homes to vasculature of pre-malignant dysplastic skin and which includes the amino acid sequence SRPRR (SEQ ID NO: 1) or a conservative variant or peptidomimetic thereof. The present invention further provides a conjugate containing a therapeutic moiety linked to a homing peptide or peptidomimetic which selectively homes to vasculature of malignant skin and which includes the amino acid sequence CGKRK (SEQ ID NO: 6) or the amino acid sequence CDTRL (SEQ ID NO: 7), or a conservative variant or peptidomimetic of one of these sequences. |
| FILED | Wednesday, October 20, 2004 |
| APPL NO | 10/970847 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723475 | Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Timothy C. Thompson (Houston, Texas); Chenghui Ren (Houston, Texas); Chengzhen Ren (Houston, Texas) |
| ABSTRACT | The invention is directed to purified and isolated novel RGL2 polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. |
| FILED | Wednesday, August 31, 2005 |
| APPL NO | 11/217067 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723483 | Clemmons et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | David R. Clemmons (Chapel Hill, North Carolina); Laura A. Maile (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention provides αVβ3 integrin cysteine loop domain agonists and antagonists (including peptide agonists and antagonists and analogs thereof), along with methods of using the same. |
| FILED | Friday, May 06, 2005 |
| APPL NO | 11/123290 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723487 | Malkas et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CS-KEYS, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Linda H. Malkas (Indianapolis, Indiana); Robert J. Hickey (Indianapolis, Indiana); Pamela E. Bechtel (Tempe, Arizona); Min Park (Los Alamos, New Mexico); Derek J. Hoelz (Indianapolis, Indiana); Dragana Tomic (Baltimore, Maryland); Lauren Schnaper (Lutherville, Maryland) |
| ABSTRACT | The method for developing an antibody that exclusively binds to csPCNA. |
| FILED | Tuesday, November 13, 2007 |
| APPL NO | 11/983939 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723497 | Gross et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington University in St. Louis (St. Louis, Missouri) |
| INVENTOR(S) | Richard W. Gross (Chesterfield, Missouri); Christopher M. Jenkins (Saint Louis, Missouri) |
| ABSTRACT | A novel function phospholipase A2, referred to herein as calcium-independent phospholipase A2ε (iPLA2ε) having SEQ ID NO: 1 and SEQ ID NO: 2, and nucleic acid sequences (SEQ ID NO: 3 and SEQ ID NO: 4) encoding and expressing iPLA2ε is disclosed. This novel enzyme has been isolated and characterized and is involved in the catalysis and hydrolysis of lipids cycling in a living cell biosystem. In an embodiment, the iPLA2ε polypeptide is encoded and expressed by an isolated nucleic acid molecule comprising a set of iPLA2ε polynucleotides. In one aspect, an isolated and characterized gene comprises a polynucleotide having a sequence shown in SEQ ID NO: 3 and SEQ ID NO: 4. |
| FILED | Monday, December 13, 2004 |
| APPL NO | 11/010558 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723500 | Krieg et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); Coley Pharmaceutical Group, Inc. (New York, New York) |
| INVENTOR(S) | Arthur M. Krieg (Wellesley, Massachusetts); Joel Kline (Iowa City, Iowa); Dennis Klinman (Potomac, Maryland); Alfred D. Steinberg (Potomac, Maryland) |
| ABSTRACT | Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed. |
| FILED | Friday, August 11, 2006 |
| APPL NO | 11/503483 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723501 | Reed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Burham Institute for Medical Research (La Jolla, California) |
| INVENTOR(S) | John C. Reed (Rancho Santa Fe, California); Shinichi Takayama (San Diego, California) |
| ABSTRACT | The present invention provides a family of BAG-1 related proteins from humans (BAG-1L, BAG-1, BAG-2, BAG-3, BAG-4 and BAG-5), the invertebrate C. elegans (BAG-1, BAG-2) and the fission yeast S. pombe (BAG-1A, BAG-1B) and the nucleic acid molecules that encode them. |
| FILED | Monday, July 16, 2007 |
| APPL NO | 11/879274 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723504 | Bakaletz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nationwide Children's Hospital, Inc. (Columbus, Ohio) |
| INVENTOR(S) | Lauren O. Bakaletz (Hilliard, Ohio); Robert S. Munson, Jr. (Hilliard, Ohio) |
| ABSTRACT | The invention relates to a mutation within the sap operon of an avirulent clone of a nontypeable strain of Haemophilus influenzae (NTHi). The invention also relates to the NTHi sap operon genes and the polypeptides encoded by these polynucleotide sequences. The invention also relates to a novel 110 kDa NTHi outer membrane protein and the polynucleotide that encodes this outer membrane protein. Methods of screening for NTHi infection, and treating and preventing NTHi related disorders are also contemplated. |
| FILED | Wednesday, November 28, 2007 |
| APPL NO | 11/946563 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723507 | Acland et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Gregory M. Acland (Kennett Square, Pennsylvania); Anna V. Kukekova (Ithaca, New York); Gustavo D. Aguirre (Philadelphia, Pennsylvania); Elaine Ostrander (Potomac, Maryland); Dayna Akey (Seattle, Washington); Orly Goldstein (Ithaca, New York) |
| ABSTRACT | The invention relates to a method for identifying dogs which are genetically normal, heterozygous for, or homozygous for the mutation primarily responsible for Collie eye anomaly (CEA). The method comprises the steps of obtaining a biological sample from a dog and testing DNA in the biological sample for the presence or absence of a 7.8 kilobase deletion within chromosome 37 in which the CEA mutation is located. No deletion is indicative of a normal dog. A deletion on one allele of chromosome 37 is indicative of a dog that is heterozygous for the CEA mutation. A deletion in both alleles of chromosome 37 are indicative of a dog that is homozygous for the CEA mutation. Also provided is a kit for identifying a dog as normal, heterozygous for, or homozygous for the CEA mutation. |
| FILED | Monday, September 22, 2008 |
| APPL NO | 12/234803 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07723536 — Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof
| US 07723536 | Smith, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees Of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Amos B. Smith, III (Merion, Pennsylvania); Thomas J. Beauchamp (Fishers, Indiana); Matthew J. LaMarche (Reading, Massachusetts); Yuping Qiu (Princeton Junction, New Jersey); Michael D. Kaufman (Lawrence, Kansas); Hirokazu Arimoto (Nagoya, Japan); David R. Jones (Milford, Ohio); Kaoru Kobayashi (Osaka, Japan) |
| ABSTRACT | Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided. |
| FILED | Thursday, February 28, 2008 |
| APPL NO | 12/072730 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/404 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723564 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Omaha, Nebraska) |
| INVENTOR(S) | Robert E. Lewis (Omaha, Nebraska); Oleg V. Chaika (Omaha, Nebraska) |
| ABSTRACT | Materials and methods for identifying agents which modulate KSR mediated signal transduction are provided. |
| FILED | Thursday, August 02, 2007 |
| APPL NO | 11/833029 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723676 | Vilkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Science and Engineering Services, Inc. (Columbia, Maryland) |
| INVENTOR(S) | Andrey Vilkov (Columbia, Maryland); Vladimir M. Doroshenko (Sykesville, Maryland) |
| ABSTRACT | A method for fragmentation of analyte ions for mass spectroscopy and a system for mass spectroscopy. The method produces gas-phase analyte ions, produces gas-phase radical species separately from the analyte ions, and mixes the gas-phase analyte ions and the radical species at substantially atmospheric pressure conditions to produce fragment ions prior to introduction into a mass spectrometer. The system includes a gas-phase analyte ion source, a gas-phase radical species source separate from the gas-phase analyte ion source, a mixing region where the gas-phase analyte ions and the radical species are mixed at substantially atmospheric pressure to produce fragment ions of the analyte ions, a mass spectrometer having an entrance where at least a portion of the fragment ions are introduced into a vacuum of the mass spectrometer, and a detector in the mass spectrometer which determines a mass to charge ratio analysis of the fragment ions. |
| FILED | Tuesday, December 18, 2007 |
| APPL NO | 11/959006 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/281 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724937 | So et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter So (Boston, Massachusetts); Bevin Engelward (Lexington, Massachusetts); Timothy Ragan (Somerville, Massachusetts); Karsten Bahlmann (Cambridge, Massachusetts); Ki Hean Kim (Belmont, Massachusetts); Lily Hsu Laiho (San Luis Obispo, California); Hayden Huang (New York, New York) |
| ABSTRACT | In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two photons into a region of interest, scanning the region of interest across a portion of the tissue, imaging a plurality of layers of the tissue in a plurality of volumes of the tissue in the region of interest, sectioning the portion of the tissue and imaging a second plurality of layers of the tissue in a second plurality of volumes of the tissue in the region of interest, detecting a fluorescence image of the tissue due to said excitation light; and processing three-dimensional data that is collected to create a three-dimensional image of the region of interest. |
| FILED | Monday, May 12, 2008 |
| APPL NO | 12/152136 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725174 | Kern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Steven E. Kern (Salt Lake City, Utah); Olinto Linares-Perdomo (Salt Lake City, Utah); Santosh Kumar Balakrishnan (Salt Lake City, Utah) |
| ABSTRACT | This disclosure provides a method of indicating a subject's reaction to different agents administered to induce anesthesia. In particular, the subject's reaction can be assessed by receiving electrical signals from first and second electrodes spatially distributed on different regions of a subject's head, and by processing the electrical signals from the electrodes to provide a first indicator of the subject's reaction to a first of the agents and a second indicator of the subject's reaction to a second agent. |
| FILED | Thursday, June 28, 2007 |
| APPL NO | 11/770355 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725178 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Peng-Sheng Chen (La Canada, California); Shengmei Zhou (Los Angeles, California) |
| ABSTRACT | Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia, myocardial ischemia, congestive heart failure and other diseased conditions of the heart associated with elevated sympathetic neural discharges in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a patient from the stellate ganglia, the thoracic ganglia, or both, and detecting increases in the sympathetic neural discharges. The methods and systems may further comprise delivering therapy to the patient in response to a detected increase in the sympathetic neural discharge, such as delivering one or more pharmacological agents; stimulating myocardial hyperinnervation in the sinus node and right ventricle of the heart of the patient; and applying cardiac pacing, cardioversion or defibrillation shocks. Pharmacologic agents which may be used in connection with the delivery of include those which are known to exert anti-arrhythmic effect and anti-convulsant agents, such as phenytoin, carbamazepine, valproate, and phenobarbitone. Other pharmacologic agents may be used to treat impending myocardial ischemia and other diseased conditions of the heart associated with elevated sympathetic neural discharges. |
| FILED | Tuesday, August 16, 2005 |
| APPL NO | 11/205923 |
| ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725192 | Eskandar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Emad Eskandar (Nahant, Massachusetts); Ziv Williams (Boston, Massachusetts) |
| ABSTRACT | The invention relates, in part, to methods of administering electrical or magnetic brain stimulation to increase learning rate. |
| FILED | Tuesday, October 10, 2006 |
| APPL NO | 11/545808 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725267 | Prabhakarpandian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Balabhaskar Prabhakarpandian (Madison, Alabama); Shivshankar Sundaram (Madison, Alabama); Kapil Pant (Huntsville, Alabama) |
| ABSTRACT | The present invention is a synthetic microfluidic microvasculature network and associated methods. The synthetic microfluidic microvasculature network mimics the structure, fluid flow characteristics, and physiological behavior of physiological microvasculature networks. Computational methods for simulating flow and particle adherence in synthetic and physiological microvascular systems and methods for determining parameters influencing particle adhesion and drug delivery are also described. The invention has many uses including the optimization of drug delivery and microvascular treatments and in describing disease mechanisms that affect the microvasculature such as inflammation, diabetes and hypertension. |
| FILED | Friday, March 31, 2006 |
| APPL NO | 11/393715 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725565 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Peter Chao-yuan Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); Mark G. Polyak (Alexandria, Virginia); James M. Wilson (Alexandria, Virginia); Jae In Yoon (Centreville, Virginia) |
| ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes. |
| FILED | Wednesday, November 19, 2008 |
| APPL NO | 12/274243 |
| ART UNIT | 2451 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/219 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07721433 | Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Ralph J. Thompson (Wells, Maine); Susan M. Tholen (Kennebunk, Maine) |
| ABSTRACT | An outer seal assembly of a turbine rotor stage is secured within a circumferential groove of the turbine casing in such a manner as to both fix the outer seal assembly in its installed position and also provide for sealing around its outer periphery so as to thereby prevent the leakage of cooling air therearound. A plurality of arcuate elements having an angle-shaped cross sectional profile are provided to interface between radially extending arms of the outer seal assembly and the inner surface of the casing, with a locking mechanism then being applied to secure the two structures in their installed positions. Each of the arcuate elements includes a radially extending panel, a plurality of forwardly extending hooks that are disposed within a groove in the casing, and a second forwardly extending flange that engages the rear surface of the outer seal assembly arm. As the outer seal assembly arm is urged rearwardly during operation, the arcuate element is caused to rotate about a fulcrum in the circumferential groove such that a radially outer edge of the radially extending panel is urged against a casing inner surface so as to thereby enhance the sealing relationship therebetween. |
| FILED | Monday, March 28, 2005 |
| APPL NO | 11/091172 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/889.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721437 | Howell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Stephen John Howell (West Newbury, Massachusetts); John Carl Jacobson (Melrose, Massachusetts); Timothy P. McCaffrey (Swampscott, Massachusetts); Barry Francis Barnes (Malden, Massachusetts) |
| ABSTRACT | A method facilitates assembling a combustor for a gas turbine engine, wherein the combustor includes a swirler assembly. The method comprises machining material to form a domeplate, positioning a sealplate including an overhanging portion against the domeplate, securing the sealplate in position relative to the domeplate with a welding process, and welding the swirler assembly to the domeplate. |
| FILED | Thursday, December 06, 2007 |
| APPL NO | 11/951765 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/889.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721478 | Withers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Materials and Electrochemical Research Corp. (Tucson, Arizona) |
| INVENTOR(S) | James C. Withers (Tucson, Arizona); Lori A. Bracamonte (Tucson, Arizona); Roger S. Storm (Tucson, Arizona); Sion M. Pickard (Tucson, Arizona); Raouf O. Loutfy (Tucson, Arizona) |
| ABSTRACT | A fabrication technique is described for producing lighter weight and improved wear and erosion resistant gun barrels. The barrels are produced in an unconventional manner from the inside bore to the outside diameter of the barrel and combine a refractory metal, metal alloy, or ceramic composite inner liner with a metal matrix composite (MMC) or titanium or other suitable high strength, lightweight metal or metal alloy outer shell. A unique aspect of the invention is that there is a compositional gradation from the liner at the inside bore to the overwrap which extends to the outside diameter of the barrel. A process is also described to produce barrels with a refractory metal liner with improved wear and erosion resistance by depositing the refractory metal on the ID of a pre-fabricated barrel. |
| FILED | Wednesday, April 27, 2005 |
| APPL NO | 11/115929 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/76.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721522 | Farah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Jorge I. Farah (Glastonbury, Connecticut); Jason Hickman (Royal Palm Beach, Florida); Jose Cintron (Tequesta, Florida) |
| ABSTRACT | A bushing for assembling an exhaust duct liner with an exhaust duct in a gas turbine engine comprises a body, a bushing opening and a first tab. The body is insertable into a duct opening in an exhaust duct. The bushing opening receives a shaft of a liner fastener, wherein the fastener is connectable with a duct liner. The first tab extends into the duct opening and prevents rotation of the liner fastener. |
| FILED | Thursday, August 31, 2006 |
| APPL NO | 11/514293 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/39.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721550 | Peters |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Donald W. Peters (Colchester, Connecticut) |
| ABSTRACT | An aircraft engine nozzle assembly includes an adjustable flap portion that is movable about a pivot for changing the size of an exhaust exit area. A bracket having a curved slot establishes a range of possible movement of the flap portion. A link includes a guide member portion that is received in the curved slot for guiding the movement of the flap portion. The link is connected to a static engine structure and the bracket is movable with the flap portion. The curved slot establishes a range of possible movement of the flap portion along a direction of the curved slot. |
| FILED | Wednesday, August 10, 2005 |
| APPL NO | 11/200895 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/771 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721666 | Sovel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James E. Sovel (Panama City Beach, Florida) |
| ABSTRACT | A line retrieve-release system is provided for mounting on the hull of a boat. Jaws are coupled to the hull of the boat and face substantially aft relative to the boat's bow. The jaws are capable of movement between a partially open position defining the system's “line retrieve” position and a fully open position defining the system's “line release” position. A latch coupled to the jaws is biased to cooperate therewith in the partially open position to thereby define a first enclosed region bounded by the jaws and latch. The latch permits one-way entry into the first enclosed region when a force is applied to the latch from outside of the first enclosed region. Line catch means are coupled to the hull of the boat aft of the jaws. The line catch means combines with the jaws in their partially open position to define a second enclosed region adjacent to the first enclosed region. The line catch means permits one-way entry to the second enclosed region when a force is applied thereto from outside of the second enclosed region. Actuator element(s) are coupled to the jaws to move them to their fully open position to thereby open both the first and second enclosed regions. The actuator elements also allow the retrieve-release system to reset to its “line retrieve” position. |
| FILED | Tuesday, September 25, 2007 |
| APPL NO | 11/973985 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/218 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721669 | Portmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Helmut Portmann (Panama City, Florida); Elan Moritz (Panama City, Florida) |
| ABSTRACT | A common payload rail externally supports a submerged payload from an unmanned marine vehicle. A vehicle interface module has a conforming surface rigidly secured to the unmanned vehicle and feed-through conduits. A functionality module is secured to the vehicle interface module and contains internal interfacing components to minimize or eliminate any modifications to the payload and vehicle. A payload interface module having feed-through conduits is secured to the functionality module and has longitudinally extending rail structures sized to engage correspondingly shaped longitudinally extending receiving means on the payload. The longitudinally extending rail structures are shaped to extend into longitudinally extending receiving means on the payload to arrest lateral displacement between the payload interface module and the payload and at least one securing mechanism on the payload interface module is disposed to engage the payload to arrest longitudinal displacement between the payload interface module and the payload. |
| FILED | Thursday, December 13, 2007 |
| APPL NO | 12/002855 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721762 | Welle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Richard P. Welle (Huntington Beach, California) |
| ABSTRACT | Embodiments of valve apparatuses are described. |
| FILED | Tuesday, July 26, 2005 |
| APPL NO | 11/190312 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/828 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721843 | Belenger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert V. Belenger (Raynham, Massachusetts); Gennaro Lopriore (Somerset, Massachusetts) |
| ABSTRACT | A visual-acoustic device is provided that contains an acoustic detector to produce sound waves in communication with a moiré pattern generator that produces moiré patterns corresponding to the sound waves. The device includes a rigid plate having a first repetitive pattern and a flexible plate spaced from the rigid, plate and having a second repetitive pattern corresponding to the first repetitive pattern. The sound waves induce movement of the flexible plate such that the second repetitive pattern moves with respect to the first repetitive pattern to produce the moiré pattern. The visual-acoustic device can be arranged as a visual-acoustic stethoscope. |
| FILED | Wednesday, February 08, 2006 |
| APPL NO | 11/357470 |
| ART UNIT | 2832 — Fluid Handling and Dispensing |
| CURRENT CPC | Acoustics 181/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722315 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Ching-Pang Lee (Cincinnati, Ohio); Eric Alan Estill (Morrow, Ohio); James Harvey Laflen (Loveland, Ohio); Paul Hadley Vitt (Hamilton, Ohio); Michael Elliot Wymore (Madison, Alabama) |
| ABSTRACT | A method of assembling a gas turbine engine includes coupling a turbine shroud assembly within the gas turbine engine. The turbine shroud assembly includes a shroud segment having a leading edge defining a forward face and a radial inner surface. A turbine nozzle is coupled to the turbine shroud assembly such that a gap is defined between an aft face of an outer band of the turbine nozzle and the forward face. A plurality of recuperated cooling openings are defined through the leading edge at an oblique inlet angle with respect to a centerline of the gap and between the forward face and the radial inner surface to direct cooling fluid through the leading edge to facilitate preferential cooling of the leading edge. |
| FILED | Thursday, November 30, 2006 |
| APPL NO | 11/565253 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722539 | Carter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); Mirabilis Medica (Seattle, Washington) |
| INVENTOR(S) | Stephen J. Carter (La Conner, Washington); Shahram Vaezy (Seattle, Washington); Roy W. Martin (Anacortes, Washington); George W. Keilman (Woodinville, Washington); Lawrence A. Crum (Bellevue, Washington) |
| ABSTRACT | A noninvasive technique that can be used to deny blood flow to a particular region of tissue, without the inherent risks associated with invasive procedures such as surgery and minimally-invasive procedures such as embolization. Blood flow in selected portions of the vasculature can be occluded by selectively treating specific portions of the vasculature with high intensity focused ultrasound (HIFU). The occlusion denies undesired tissue the nutrients and oxygen provided by blood flow, causing necrosis in the undesired tissue. An imaging technology (such as magnetic resonance imaging, magnetic resonance angiography, ultrasound imaging, Doppler based ultrasound imaging, or computed tomographic angiography) is used to identify the undesired tissue, and the vascular structures associated with the undesired tissue. A portion of the vasculature providing blood flow to the undesired tissue is selected, and HIFU is administered to the selected portion of the vasculature to occlude blood flow through that portion of the vasculature. |
| FILED | Thursday, August 18, 2005 |
| APPL NO | 11/207554 |
| ART UNIT | 3768 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Surgery 6/439 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722782 | Coffey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rechargeable Battery Corporation (College Station, Texas) |
| INVENTOR(S) | Brendan Coffey (Austin, Texas); Ramesh C. Kainthla (College Station, Texas); Charles Edward Sesock (College Station, Texas) |
| ABSTRACT | A particulate composite fuel of metal preferably of aluminum for a portable heater. The fuel reacts with oxygen in the air, producing heat. The composite fuel may also be flaked aluminum or iron nanopowder. A portable heater having a fuel mass, at least one thermal conductive member, and at least one insulating member. The heater transfers the heat of the oxidation of the metal particulate fuel to a desired mass to be heated, typically a food item. The multilayered heater also acts as a buffer absorbing released heat and releasing the heat to the desired mass at a rate slower than the absorbing. |
| FILED | Wednesday, July 12, 2006 |
| APPL NO | 11/486400 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions 252/70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722809 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hongrui Jiang (Madison, Wisconsin); David J. Beebe (Madison, Wisconsin) |
| ABSTRACT | A detection device is provided for detecting the presence of an agent in a fluid. The device includes a body defining first and second chambers. It is intended for the first chamber accommodating the flow of fluid therein. A first valve is disposed in the body between in the first and second chambers. The first valve opens in response to the presence of the agent in the fluid. A first detection structure is disposed in the second chamber in order to generate a predetermined signal in response to exposure to the fluid. |
| FILED | Friday, June 03, 2005 |
| APPL NO | 11/144723 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/58 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722816 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hongrui Jiang (Madison, Wisconsin); Sudheer S. Sridharamurthy (Madison, Wisconsin) |
| ABSTRACT | A detection device and method for detecting the presence of an agent in a fluid. The device includes a membrane having first and second sides. The membrane allows a stimulus, e.g. ultraviolet light, to dissolve in response to presence of the agent. A source is positioned on a first side of the membrane. The source sources the stimulus toward the membrane. A detection structure is disposed on the second side of the membrane for detecting the stimulus. The detection structure generates an output voltage in response to the intensity of the stimulus detected. As the membrane dissolves, the intensity of the stimulus detected changes. |
| FILED | Thursday, May 24, 2007 |
| APPL NO | 11/753167 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722836 | Doyle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Edward F. Doyle (Phoenix, Maryland); Alan T. Seitzinger (Abingdon, Maryland); John T. Lawton (Killen, Alabama); Jerry W. Owen (Tuscumbia, Alabama); Grady Lynn Holt (Florance, Alabama); Joseph T. Johnson (Segnal Mountain, Indiana) |
| ABSTRACT | The Chemical-agent Access and Neutralization System (CANS) of the present invention is a small, portable, single-use, disposable chemical treatment apparatus that is used to access and treat Chemical Agent Identification Set (CAIS) ampoules, bottles and/or containers that contain vesicant agents, or chemical warfare agents such as mustard or Lewisite. The apparatus and method of use of the present invention provides a resultant treatment residue that remains totally contained in the CANS treatment container and is safe for disposal. The CANS treatment container can be over packed into a Department of Transportation (DOT) certified shipping container, and shipped to permitted hazardous waste management facilities for ultimate disposal. |
| FILED | Friday, August 24, 2007 |
| APPL NO | 11/844535 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/237 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722851 | Keller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Teddy M Keller (Fairfax Station, Virginia); Syed B Qadri (Fairfax Station, Virginia) |
| ABSTRACT | A process of making carbon nanotubes comprising the steps of: providing a precursor composition comprising at least one metallic compound and at least one organic compound; wherein the organic compound is selected from the group consisting of an ethynyl compound, a metal-ethynyl complex, and combinations thereof; wherein the precursor composition is a liquid or solid at room temperature; and heating the precursor composition under conditions effective to produce carbon nanotubes. A carbon nanotube composition comprising carbon nanotubes and a metal component selected from the group consisting of metal nanoparticles and elemental metal; wherein the carbon nanotube composition is rigid. |
| FILED | Tuesday, February 12, 2008 |
| APPL NO | 12/029484 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722889 | Duffy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Seattle Biomedical Research Institute (Seattle, Washington); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Patrick Duffy (Seattle, Washington); Urszula Krzych (Washington, District of Columbia); Donald G. Heppner, Jr. (Vienna, Virginia); Vladislav A. Malkov (Seattle, Washington); Jason W. Wendler (Lincoln, Nebraska); Igor Bacik (Rockville, Maryland) |
| ABSTRACT | The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria. |
| FILED | Friday, September 29, 2006 |
| APPL NO | 12/088065 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/268.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722927 | Shtein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Max Shtein (Princeton, New Jersey); Stephen R. Forrest (Ann Arbor, Michigan); Jay B. Benzinger (Lawrenceville, New Jersey) |
| ABSTRACT | A device and a method for facilitating the deposition and patterning of organic materials onto substrates utilizing the vapor transport mechanisms of organic vapor phase deposition is provided. The device includes one or more nozzles, and an apparatus integrally connected to the one or more nozzles, wherein the apparatus includes one or more source cells, a carrier gas inlet, a carrier gas outlet, and a first valve capable of controlling the flow of a carrier gas through the one or more source cells. The method includes moving a substrate relative to an apparatus, and controlling the composition of the organic material and/or the rate of the organic material ejected by the one or more nozzles while moving the substrate relative to the apparatus, such that a patterned organic layer is deposited over the substrate. |
| FILED | Friday, July 18, 2008 |
| APPL NO | 12/175641 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/255.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722928 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Seunghun Hong (Chicago, Illinois); Vinayak P. Dravid (Glenview, Illinois) |
| ABSTRACT | In one aspect, a method of nanolithography is provided using a driving force to control the movement of a deposition compound from a scanning probe microscope tip to a substrate. Another aspect of the invention provides a tip for use in nanolithography having an internal cavity and an aperture restricting movement of a deposition compound from the tip to the substrate. The rate and extent of movement of the deposition compound through the aperture is controlled by a driving force. |
| FILED | Thursday, April 07, 2005 |
| APPL NO | 11/100483 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723017 | Bitensky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Mark W Bitensky (Waban, Massachusetts); Tatsuro Yoshida (West Newton, Massachusetts) |
| ABSTRACT | There are provided methods and compositions for the storage of red blood cells. The compositions are metabolic supplements that are preferably added to refrigerated red blood cells suspended in an additive solution. Red blood cells are preferably stored under conditions of oxygen-depletion. Metabolic compositions comprises pyruvate, inosine, adenine, and optionally dibasic sodium phosphate and/or monobasic sodium phosphate. |
| FILED | Thursday, May 26, 2005 |
| APPL NO | 11/138135 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723069 | Soll et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Dieter Soll (Hamden, Connecticut); Jesse Rinehart (New Haven, Connecticut) |
| ABSTRACT | Nucleic acids encoding genes with SepRS and tRNASep activity for site specific incorporation of phosphoserine into a protein or polypeptide and methods of use thereof are described. Typically, SepRS preferentially aminoacylates tRNASep with O-phosphoserine and the tRNASep recognizes at least one codon such as a stop codon. In a preferred embodiment the nucleic acids are on vectors. In one embodiment, the vectors are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. In an alternative embodiment, the vectors are expressed in an in vitro transcription/translation system. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery. |
| FILED | Monday, April 03, 2006 |
| APPL NO | 11/396439 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723070 | Tirrell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David A. Tirrell (Pasadena, California); Kristi Lynn Kiick (Altadena, California) |
| ABSTRACT | Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallylglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine. |
| FILED | Monday, February 05, 2007 |
| APPL NO | 11/671378 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723109 | Lewis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Randolph V. Lewis (Laramie, Wyoming) |
| ABSTRACT | The present invention relates to the fields of molecular biology and plant biology. Specifically, the invention is directed to the methods for expressing spider silk proteins in plants and the synthesis and purification of spider silk proteins therefrom. |
| FILED | Monday, October 29, 2007 |
| APPL NO | 11/926871 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723126 | Denes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ferencz S. Denes (Madison, Wisconsin); Sorin Odisei Manolache (Madison, Wisconsin); Jason M. Helgren (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Bradley James Larson (Madison, Wisconsin) |
| ABSTRACT | Methods for producing plasma-treated, functionalized inorganic oxide surfaces are provided. The methods include the steps of subjecting an oxide surface to a plasma to create hydroxyl functionalities on the surface and reacting the hydroxyl functionalities with epoxy group-containing molecules in situ in the absence of plasma. Biomolecules may be immobilized on the resulting functionalized surfaces. The methods may be used to treat a variety of oxide surfaces, including glass, quartz, silica and metal oxides. |
| FILED | Wednesday, March 24, 2004 |
| APPL NO | 10/809318 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/525 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723154 | Adekore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raliegh, North Carolina); LumenZ, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Bunmi T. Adekore (Medford, Massachusetts); Jonathan M. Pierce (Raleigh, North Carolina); Robert F. Davis (Pittsburgh, Pennsylvania); George B. Kenney (Medfield, Massachusetts) |
| ABSTRACT | A p-type ZnO-based II-VI compound semiconductor layer has silver, potassium and/or gold dopants therein at a net p-type dopant concentration of greater than about 1×1017 cm−3. A method of forming the layer includes using an atomic layer deposition (ALD) technique. This technique includes exposing a substrate to a combination of gases: a first reaction gas containing zinc at a concentration that is repeatedly transitioned between at least two concentration levels during a processing time interval, a second reaction gas containing oxygen and a p-type dopant gas containing at least one p-type dopant species selected from a group consisting of silver, potassium and gold. A concentration of oxygen in the second reaction gas may also be repeatedly transitioned between at least two concentration levels. The concentration of zinc in the first reaction gas and the concentration of oxygen in the second reaction gas may be transitioned in an alternating sequence, so that relatively high zinc concentrations in the first reaction gas overlap with relatively low oxygen concentrations in the second reaction gas and vice versa. |
| FILED | Thursday, October 19, 2006 |
| APPL NO | 11/551058 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723311 | Seeney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | NanoBioMagnetics, Inc. (, None); The University of Oklahoma Hough Ear Institute (, None); The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Charles E. Seeney (Edmond, Oklahoma); Kenneth J. Dormer (Edmond, Oklahoma); Richard D. Kopke (Oklahoma City, Oklahoma) |
| ABSTRACT | A system for introducing a bioactive substance into a target cell within a body. The bioactive substance is transported to the target cell using a superparamagnetic nanoparticle and a controllable magnetic field generator that is capable of moving the nanoparticle to the target cell through the body in three dimensions. The nanoparticle may be covered with a biocompatible shell that forms a covalent bond with the bioactive substance. In an alternative embodiment, the bioactive substance and a plurality of nanoparticles are supported by a bioerodable matrix that forms a nanosphere. The nanosphere may be moved into the target cell using an external magnetic field that is controllable to move the nanosphere in three dimensions through the body and the bioactive substance is released from the nanosphere once inside the target cell. |
| FILED | Friday, June 18, 2004 |
| APPL NO | 10/871243 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723420 | Laskoski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Laskoski (Springfield, Virginia); Teddy M Keller (Fairfax Station, Virginia) |
| ABSTRACT | An oligomer having the formula: Ar1 and Ar2 are each an aromatic group or a bisphenol residue. At least one of Ar1 and Ar2 is the aromatic group. The value of m is zero or one, and n is a positive integer. A polymer made by reacting the above oligomer with a crosslinker having at least two silyl hydrogen atoms. A method of: reacting a compound having the formula: with vinyl(dimethylchloro)silane to form the above oligomer. T is —OH, —Br, or —I. |
| FILED | Friday, July 25, 2008 |
| APPL NO | 12/179664 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 524/430 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723454 | Keller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Teddy M Keller (Fairfax Station, Virginia); Manoj K. Kolel-Veetil (Alexandria, Virginia) |
| ABSTRACT | A fiber of linear polymer coated with a siloxane-carborane polymer or a thermoset or ceramic made therefrom. An organic fiber coated with a siloxane-carborane polymer or a thermoset or ceramic made therefrom and a surfactant. An organic fiber coated with a siloxane-carborane polymer made from a hydrosilation reaction of a siloxane-carborane compound containing at least two unsaturated carbon-carbon bonds and a silane compound or a thermoset or ceramic made therefrom. A method of coating a fiber by contacting a fiber to an aqueous solution of a siloxane-carborane polymer and a surfactant or to a solution of a siloxane-carborane polymer in a non-halogenated organic solvent. A method of contacting a fiber to a solution of a siloxane-carborane polymer, drying the coating to a temperature that does not change the polymer to a thermoset or ceramic, and using the dried, coated fiber in a process that requires that the fiber be flexible. |
| FILED | Wednesday, August 30, 2006 |
| APPL NO | 11/468331 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 528/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723487 | Malkas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CS-KEYS, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Linda H. Malkas (Indianapolis, Indiana); Robert J. Hickey (Indianapolis, Indiana); Pamela E. Bechtel (Tempe, Arizona); Min Park (Los Alamos, New Mexico); Derek J. Hoelz (Indianapolis, Indiana); Dragana Tomic (Baltimore, Maryland); Lauren Schnaper (Lutherville, Maryland) |
| ABSTRACT | The method for developing an antibody that exclusively binds to csPCNA. |
| FILED | Tuesday, November 13, 2007 |
| APPL NO | 11/983939 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723558 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Tu-Chen Cheng (Timonium, Maryland); Joseph J. DeFrank (Bel Air, Maryland); Steven P. Harvey (Fallston, Maryland); Vipin K. Rastogi (Bel Air, Maryland) |
| ABSTRACT | The present invention relates to a near-universal non-corrosive, non-toxic, environmentally safe and user friendly decontaminant capable of detoxifying organophosphorus (OP)-based G-type, V-type neurotoxic chemical warfare, sulfur-mustard, and related OP based hazardous industrial materials in a dry powder form. The decontaminant contains OPH enzyme, OPAA enzyme, DFPase enzyme, dehalogenase enzyme, quaternary ammonium salt, a pH control reagent, a fire-fighting agent, and a foaming agent. The decontaminant is mixed with available water for use. |
| FILED | Tuesday, June 05, 2007 |
| APPL NO | 11/758431 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Hazardous or toxic waste destruction or containment 588/408 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723684 | Haddon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert C. Haddon (Riverside, California); Mikhail E. Itkis (Riverside, California) |
| ABSTRACT | Systems and methods for designing and fabricating carbon nanotube based detectors are disclosed. In some embodiments, one or more sensor elements can be formed from a film of single-walled carbon nanotubes (SWNTs). Bolometric properties of such detectors are disclosed. In some embodiments, the film can be thermally isolated in various ways, such as suspending the film and providing a vacuum environment, to provide the bolometric properties. Various properties of the SWNT films, such as resistivity-dependence on temperature and spectral response, can be obtained by adjusting the dimension and/or composition of the film. Examples of SWNT film formation, detector element fabrication, and array fabrication are disclosed. |
| FILED | Tuesday, January 30, 2007 |
| APPL NO | 11/668826 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723851 | La Tulipe, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Douglas C. La Tulipe, Jr. (Guilderland, New York); Mark Todhunter Robson (Danbury, Connecticut) |
| ABSTRACT | A method of forming a high aspect ratio via opening through multiple dielectric layers, a high aspect ratio electrically conductive via, methods of forming three-dimension integrated circuits, and three-dimensional integrated circuits. The methods include forming a stack of at least four dielectric layers and etching the first and third dielectric layers with processes selective to the second and fourth dielectric layers, etching the second and third dielectric layers with processes selective to the first and second dielectric layers. Advantageously the process used to etch the third dielectric layer is not substantially selective to the first dielectric layer. |
| FILED | Tuesday, September 11, 2007 |
| APPL NO | 11/853118 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/761 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723941 | Roach et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey M. Roach (St. Charles, Missouri); Steven H. Degroote (Creve Coeur, Missouri) |
| ABSTRACT | A system and method of command signal conditioning in high response systems is disclosed. The system includes a central digital controller having a digital controller frame rate, a motor, a motor controller in communication with the digital controller and the motor, the motor controller having a motor controller frame rate higher than the digital controller frame rate, and a signal conditioner adapted to condition the command signal to produce a modified command signal at the motor controller frame rate. The signal conditioner is preferably implemented in software. In one embodiment, the signal conditioner is adapted to calculate a moving average at the frame rate of the motor controller. In another embodiment, the signal conditioner comprises a first order hold and a filter in communication therewith. A method of command signal conditioning in accordance with the foregoing is also disclosed. |
| FILED | Monday, December 29, 2003 |
| APPL NO | 10/748001 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Motive power systems 318/600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724103 | Feng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Xiao-Li Feng (Pasadena, California); Christopher J. White (Palo Alto, California); Seyed Ali Hajimiri (Pasadena, California); Michael L. Roukes (Pasadena, California) |
| ABSTRACT | A self-sustaining ultra-high frequency oscillator and method enable the ability to oscillate and output a signal. A balanced bridge circuit is utilized to null an embedding background response. A first vibrating nanoelectromechanical (NEMS) beam resonator is part of one of the branches of the balanced bridge circuit and determines the frequency of the oscillator's output signal. A feedback loop establishes and sets oscillation conditions of the oscillator's signal. Further, the feedback loop connects an output of the first resonator to an input of the balanced bridge circuit. |
| FILED | Wednesday, February 13, 2008 |
| APPL NO | 12/030815 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Oscillators 331/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724168 | Cruz-Albrecht et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Jose Cruz-Albrecht (Oak Park, California); Peter Petre (Oak Park, California) |
| ABSTRACT | A system for making a pulse domain linear programming circuit. The inputs and the outputs to the pulse domain linear programming circuit are time encoded pulse signals. The circuit includes arrays of two types of cross-coupled time encoding elements. The first type of elements includes two integrators, adders, a hysteresis quantizer, and a 1-bit self-feedback DAC. The second type of elements includes a bias element, a leaky integrator, adders, a fixed memory-less non-linearity, a regular integrator, a hysteresis quantizer and a 1-bit self-feedback DAC. The cross-coupling signals between the two types of elements are pulse time-encoded signals. All of the cross-coupling weights are set via 1-bit DACs having variable gains. The cross-coupling weights are used to set a constraint equation of a pulse domain linear programming problem. Methods to make the foregoing circuit are also described. |
| FILED | Friday, October 31, 2008 |
| APPL NO | 12/262782 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Coded data generation or conversion 341/138 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724183 | Mountcastle |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Technology Service Corporation (Silver Spring, Maryland) |
| INVENTOR(S) | Paul D. Mountcastle (Huntington, Connecticut) |
| ABSTRACT | A method of imaging a moving object, including the steps of: acquiring radar data reflected by the moving object, determining a motion state of the moving object; and generating a three-dimensional representation of the moving object based on the determined motion state, is disclosed. The motion state may be a complete solution of translational and rotational motion determined based on at least one of the inertia tensor components of the moving object, or solutions of Euler's torque-free equations of motions. The three-dimensional representation may be generated by reconstructing static patterns of the moving object based on estimated initial translational and rotational conditions of the object. A system for imaging the moving object according to this method is also disclosed. |
| FILED | Friday, October 19, 2007 |
| APPL NO | 11/907988 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/180 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724190 | Wei |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jerome H. Wei (La Habra, California) |
| ABSTRACT | Embodiments of the disclosure provide methods, apparatus, and articles related to code combination for GPS III, and more particularly, to methods and apparatuses for enabling signal modulation that potentially may minimize power throw away for target code power ratios by shifting linear signal constellation points radially to a circle of equal amplitude, e.g., where the circumference represents e.g. the average RMS power of the original linear signals. |
| FILED | Tuesday, October 02, 2007 |
| APPL NO | 11/866149 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/386 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724197 | Hardie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Planet Earth Communications, LLC (Mountain View, California) |
| INVENTOR(S) | George S. Hardie (Datil, New Mexico); Michael J. Maybell (Mountain View, California); Brian M. Cover (Scottsdale, Arizona); Michael S. Davis (Longmont, Colorado) |
| ABSTRACT | A parallel plate beam forming lens is formed form at least three parallel plates, and includes a plurality of beam port waveguides, each coupled to a beam port divider with a step increase in waveguide height. The beam port divider comprises a first divider having two outputs separated by a resistive septum, each of which is coupled to a second divider having two outputs separated by a resistive septum, with all of the second divider outputs coupled to a lens region through beam port apertures. On the opposite end from the beam port waveguides is a plurality of array port waveguides forming a transformer, thereafter to a section of waveguide, and thereafter to an array port divider including a resistive septum coupled to the lens region and a step decrease in waveguide height. Also positioned at the extents of the beam port apertures and the array port apertures are a plurality of dummy ports. The beam port waveguides and array port waveguides are equalized in length using a feedthrough structure and a jog structure. The array port dividers, lens region, and beam port dividers are formed from the second and third plate, while the waveguides are formed from the first and second plate, with the feedthrough and jog structures formed on a combination of all three plates. |
| FILED | Monday, April 30, 2007 |
| APPL NO | 11/799595 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/754 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724202 | Mayes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan R. Mayes (Austin, Texas); Mark G. Mayes (Austin, Texas) |
| ABSTRACT | An apparatus providing a low impedance transition from a pulse generator to one or more helical antennae. Conventional transition from coaxial-to-antenna causes energy loss. The present invention decreases that loss. |
| FILED | Thursday, July 03, 2008 |
| APPL NO | 12/217378 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/859 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724319 | Abbott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Jeffrey M. Brake (Newark, Delaware) |
| ABSTRACT | A method of forming a liquid crystal device, includes: contacting an aqueous solution comprising a surfactant and a receptor molecule with a top surface of a liquid crystal. The liquid crystal is in a holding compartment of a substrate, and the receptor molecule is adsorbed on the top surface of the liquid crystal forming an interface between the liquid crystal and the aqueous solution. The receptor molecule is different than the surfactant. A method of detecting a compound in a flowing stream includes passing an aqueous solution over a top surface of a liquid crystal in a holding compartment of a substrate. The method also includes determining whether a change in the orientation of the liquid crystal occurs as the aqueous solution is passed over the top surface of the liquid crystal. A change in the orientation of the liquid crystal indicates the presence of the compound in the flowing stream. |
| FILED | Wednesday, November 26, 2008 |
| APPL NO | 12/324403 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid crystal cells, elements and systems 349/58 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724500 | Long et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey W. Long (Alexandria, Virginia); Anne E. Fischer (Arlington, Virginia); Debra R. Rolison (Arlington, Virginia) |
| ABSTRACT | A composite concerning a porous carbon structure having a surface and pores and a coating of MnO2 on the carbon surface, wherein the coating does not completely fill or obstruct a majority of the pores, and wherein the coating is formed by self-limiting electroless deposition. |
| FILED | Friday, July 13, 2007 |
| APPL NO | 11/826362 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/502 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724566 | Sundstrom |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lance L. Sundstrom (Pinellas Park, Florida) |
| ABSTRACT | A magnetoresistive resistor memory cell having four individually polarizable magnetoresistive resistors that form a magnetoresistive bridge circuit. Each of the four magnetoresistive resistors is surrounded by a write trace segment pair. One upper write trace segment is directly above a magnetoresistive resistor and one lower write trace segment is directly below that resistor. The two write traces of a write trace segment pair are oriented at 90 degrees relative to the anisotropic axis, that is, the length, of the magnetoresistive resistor. The combination of the magnetoresistive resistor bridge circuit and four write trace segment pairs forms a magnetoresistive resistor memory cell. |
| FILED | Wednesday, August 27, 2008 |
| APPL NO | 12/230282 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724782 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Xinyuan Wang (Clifton, Virginia); Shiping Chen (Dublin, California) |
| ABSTRACT | An interval centroid-based watermark encoder encodes a watermark into a packet flow. Intervals are defined for the packet flow. Some of the intervals are selected as group A intervals while other intervals are selected as group B intervals. Group A and group B intervals are paired and assigned to watermark bits. A first or second value may be encoded by increasing the relative packet time between packets in either the group A (for the first bit value) or group B (for the second bit value) interval(s) of the interval pair(s) assigned to the watermark bits that are to represent the first or second bit value and the beginning of the same group interval(s). The relative packet times may be measured by a decoder and used to calculate a centroid difference for each interval pair. The centroid differences may be used to reconstruct the watermark. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/051882 |
| ART UNIT | 2461 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/514 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724786 | Bouma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Brett Eugene Bouma (Quincy, Massachusetts); Seok-Hyun (Andy) Yun (Cambridge, Massachusetts); Wang-Yuhl (William) Oh (Cambridge, Massachusetts); Johannes F. De Boer (Somerville, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts) |
| ABSTRACT | An apparatus and source arrangement for filtering an electromagnetic radiation can be provided which may include at least one spectral separating arrangement configured to physically separate one or more components of the electromagnetic radiation based on a frequency of the electromagnetic radiation. The apparatus and source arrangement may also have at least one continuously rotating optical arrangement which is configured to receive at least one signal that is associated with the one or more components. Further, the apparatus and source arrangement can include at least one beam selecting arrangement configured to receive the signal. |
| FILED | Friday, April 11, 2008 |
| APPL NO | 11/867953 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724796 | Forrest et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Stephen Forrest (Ann Arbor, Michigan); Noel Giebink (Ann Arbor, Michigan) |
| ABSTRACT | A device comprising an organic light emitting layer may be optically pumped to create excited states within the layer. When an electric field is applied across the layer, the excited states may dissociate into geminate polaron pairs within the organic layer. The dissociated states may change back to excitons when the electric field is rapidly reduced or removed. The organic light emitting layer may be optically pumped by an adjacent OLED, allowing for an electrically-driven device. |
| FILED | Tuesday, August 29, 2006 |
| APPL NO | 11/511356 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/46.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724994 | Pepper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | David M. Pepper (Malibu, California); David Sumida (Los Angeles, California) |
| ABSTRACT | An optical time delay module has a plurality of time delay elements connected in a series and a plurality an optical output couplers wherein each of said optical output couplers is operationally connected between one or more time delay elements in said series, the optical output couplers providing a plurality of optical outputs from said module with different optical delays controlled by a digital control word. |
| FILED | Monday, February 04, 2008 |
| APPL NO | 12/025643 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725037 | VanDevender et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Aaron Pace VanDevender (Champaign, Illinois); Paul G. Kwiat (Savoy, Illinois) |
| ABSTRACT | A method and apparatus for switching at least one wavelength component of an optical signal beam from a first state to a second state. The phase characterizing the optical signal component is incremented by interaction with one or more escort beams in a non-linear medium thereby switching the state of the optical signal component on the basis of its incremented phase. Multiple escort beams may also be employed to switch different wavelength components of the signal. The method may be employed to achieve high speed, and substantially transparent, switching of phase, intensity or polarization of a signal. |
| FILED | Monday, November 13, 2006 |
| APPL NO | 11/598510 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725236 | Delaloye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Jim E. Delaloye (Mesa, Arizona); Mike W. Rettler (Peoria, Arizona) |
| ABSTRACT | A system and method for controlling the rotational speed of a gas turbine engine in an aircraft includes appropriate devices and processes for determining a pressure of lubricant supplied to the turbine engine, and for determining a maneuver state of the aircraft. The rotational speed of the gas turbine engine is controlled based at least partially on the determined pressure and the determined maneuver state. Thus, if the aircraft is in a maneuver state that may cause a reduction or loss of lubricant to the gas turbine engine, the rotational speed of the gas turbine engine can be reduced to a magnitude sufficient to increase turbomachine tolerance to the reduced or no lubricant flow. |
| FILED | Thursday, February 15, 2007 |
| APPL NO | 11/707703 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725269 | Kessler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Metis Design Corporation (Cambridge, Massachusetts) |
| INVENTOR(S) | Seth S. Kessler (Brookline, Massachusetts); Kristin A. Jugenheimer (Cambridge, Massachusetts); Aaron B. Size (Cambridge, Massachusetts) |
| ABSTRACT | A device for use in detecting an event in a structure includes a sensor encapsulation, the encapsulation containing a sensor, an actuator positioned substantially in-plane to the sensor within the housing and a printed circuit board in communication with at least one of the sensor and the actuator. The printed circuit board includes a microprocessor constructed and arranged to collect data from at least one of the sensor and the actuator, a signal generator constructed and arranged to provide excitation to at least one of the sensor and the actuator, and an amplifier to condition the excitation. |
| FILED | Monday, March 03, 2008 |
| APPL NO | 12/041416 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725298 | Levine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Frank Eliot Levine (Austin, Texas); Milena Milenkovic (Madison, Alabama); Robert J. Urquhart (Austin, Texas) |
| ABSTRACT | An improved method, apparatus, and computer instructions for generating trace data. In response to detecting a new trace event, a determination is made as to whether the new trace event occurred at an expected period of time with respect to a prior trace event. A time stamp in the trace data is placed in response to a determination that the new trace event did not occur at the expected period of time, wherein time stamps occurring at the expected period if time are eliminated from the trace data and wherein compression of the trace data occurs. |
| FILED | Thursday, December 13, 2007 |
| APPL NO | 11/955535 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/187 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725565 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Peter Chao-yuan Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); Mark G. Polyak (Alexandria, Virginia); James M. Wilson (Alexandria, Virginia); Jae In Yoon (Centreville, Virginia) |
| ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes. |
| FILED | Wednesday, November 19, 2008 |
| APPL NO | 12/274243 |
| ART UNIT | 2451 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/219 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725595 | Geissler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William Karl Geissler (Stafford, Virginia); John Colin McEachen (Carmel, California) |
| ABSTRACT | A method and system for steganography and steganalytic techniques are provided for effecting embedded communications in a variety of communication environments. One aspect may include an embedded transmitter for inserting embedded data into a packet and an embedded receiver for receiving the packet via, for example, a packetized communication network such as the Internet. Various aspects of the present invention provide robust communications with optimized throughput and may include various error handlers to maximize performance and ensure transfer of incorrupt data. A method for identifying and blocking embedded communications is also provided. |
| FILED | Tuesday, May 24, 2005 |
| APPL NO | 11/138699 |
| ART UNIT | 2457 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/235 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725682 | Gschwind et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael Gschwind (Chappaqua, New York); Balaram Sinharoy (Poughkeepsie, New York) |
| ABSTRACT | Methods and apparatus are provided for sharing storage and execution resources between architectural units in a microprocessor using a polymorphic function unit. A method for executing instructions in a processor having a polymorphic execution unit includes the steps of reloading a state associated with a first instruction class and reconfiguring the polymorphic execution unit to operate in accordance with the first instruction class, when an instruction of the first instruction class is encountered and the polymorphic execution unit is configured to operate in accordance with a second instruction class. The method also includes the steps of reloading a state associated with a second instruction class and reconfiguring the polymorphic execution unit to operate in accordance with the second instruction class, when an instruction of the second instruction class is encountered and the polymorphic execution unit is configured to operate in accordance with the first instruction class. |
| FILED | Tuesday, January 10, 2006 |
| APPL NO | 11/329320 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/43 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07721535 | Ruth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cummins Inc. (Columbus, Indiana) |
| INVENTOR(S) | Michael J. Ruth (Franklin, Indiana); Michael J. Cunningham (Greenwood, Indiana) |
| ABSTRACT | A method for modifying a NOx adsorber regeneration triggering variable. Engine operating conditions are monitored until the regeneration triggering variable is met. The adsorber is regenerated and the adsorbtion efficiency of the adsorber is subsequently determined. The regeneration triggering variable is modified to correspond with the decline in adsorber efficiency. The adsorber efficiency may be determined using an empirically predetermined set of values or by using a pair of oxygen sensors to determine the oxygen response delay across the sensors. |
| FILED | Friday, December 08, 2006 |
| APPL NO | 11/636184 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721543 | Massey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | Mary Cecelia Massey (San Antonio, Texas); Thomas Earl Boberg (San Antonio, Texas) |
| ABSTRACT | The present invention relates to a system and method for cooling a combustion gas charge prior. The combustion gas charge may include compressed intake air, exhaust gas, or a mixture thereof. An evaporator is provided that may then receive a relatively high temperature combustion gas charge and discharge at a relatively lower temperature. The evaporator may be configured to operate with refrigeration cycle components and/or to receive a fluid below atmospheric pressure as the phase-change cooling medium. |
| FILED | Monday, October 23, 2006 |
| APPL NO | 11/551871 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/618 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722731 | Routbort et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jules L. Routbort (Naperville, Illinois); Dileep Singh (Naperville, Illinois); Kenneth C. Goretta (Tokyo, Japan); Felipe Gutierrez-Mora (Seville, Spain) |
| ABSTRACT | A method for utilizing plastic deformation resulting from grain boundary sliding with or without a novel joint compound that leads to the joining of advanced ceramic materials, intermetallics, and cermets. A joint formed by this approach is as strong as or stronger than the materials joined. The method does not require elaborate surface preparation or application techniques. The method also allows for the formation of transparent joints between two subunits of a construct joined via plastic deformation. The method can be used to tailor residual stresses and maintain native porosity. |
| FILED | Tuesday, December 12, 2006 |
| APPL NO | 11/637635 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/89.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722757 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | William E. Miller (Naperville, Illinois); Victor A. Maroni (Naperville, Illinois); James L. Willit (Batavia, Illinois) |
| ABSTRACT | A method and device for the production of hydrogen from water and electricity using an active metal alloy. The active metal alloy reacts with water producing hydrogen and a metal hydroxide. The metal hydroxide is consumed, restoring the active metal alloy, by applying a voltage between the active metal alloy and the metal hydroxide. As the process is sustainable, only water and electricity is required to sustain the reaction generating hydrogen. |
| FILED | Friday, September 29, 2006 |
| APPL NO | 11/536979 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/637 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722966 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Se-Hee Lee (Lakewood, Colorado); C. Edwin Tracy (Golden, Colorado); J. Roland Pitts (Lakewood, Colorado) |
| ABSTRACT | Nano-composite materials are disclosed. An exemplary method of producing a nano-composite material may comprise co-sputtering a transition metal and a refractory metal in a reactive atmosphere. The method may also comprise co-depositing a transition metal and a refractory metal composite structure on a substrate. The method may further comprise thermally annealing the deposited transition metal and refractory metal composite structure in a reactive atmosphere. |
| FILED | Wednesday, May 11, 2005 |
| APPL NO | 11/128148 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/702 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723069 | Soll et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Dieter Soll (Hamden, Connecticut); Jesse Rinehart (New Haven, Connecticut) |
| ABSTRACT | Nucleic acids encoding genes with SepRS and tRNASep activity for site specific incorporation of phosphoserine into a protein or polypeptide and methods of use thereof are described. Typically, SepRS preferentially aminoacylates tRNASep with O-phosphoserine and the tRNASep recognizes at least one codon such as a stop codon. In a preferred embodiment the nucleic acids are on vectors. In one embodiment, the vectors are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. In an alternative embodiment, the vectors are expressed in an in vitro transcription/translation system. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery. |
| FILED | Monday, April 03, 2006 |
| APPL NO | 11/396439 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723077 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Synthetic Genomics, Inc. (San Diego, California) |
| INVENTOR(S) | Lei Young (Rockville, Maryland); Hamilton O. Smith (Reisterstown, Maryland); Daniel Glenn Gibson (Crofton, Maryland) |
| ABSTRACT | The present invention relates, e.g., to in vitro method, using isolated protein reagents, for joining two double stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity, comprising contacting the two DNA molecules in a reaction mixture with (a) a non-processive 5′ exonculease; (b) a single stranded DNA binding protein (SSB) which accelerates nucleic acid annealing; (c) a non strand-displacing DNA polymerase; and (d) a ligase, under conditions effective to join the two DNA molecules to form an intact double stranded DNA molecule, in which a single copy of the region of sequence identity is retained. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. |
| FILED | Friday, August 11, 2006 |
| APPL NO | 11/502746 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723114 | Coates, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | John T. Coates, Jr. (Anderson, South Carolina); Timothy A. DeVol (Clemson, South Carolina) |
| ABSTRACT | Disclosed are materials and systems useful in determining the existence of radionuclides in an aqueous sample. The materials provide the dual function of both extraction and scintillation to the systems. The systems can be both portable and simple to use, and as such can beneficially be utilized to determine presence and optionally concentration of radionuclide contamination in an aqueous sample at any desired location and according to a relatively simple process without the necessity of complicated sample handling techniques. The disclosed systems include a one-step process, providing simultaneous extraction and detection capability, and a two-step process, providing a first extraction step that can be carried out in a remote field location, followed by a second detection step that can be carried out in a different location. |
| FILED | Wednesday, January 10, 2007 |
| APPL NO | 11/621744 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723394 | Klimov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Victor L. Klimov (Los Alamos, New Mexico); Melissa A. Petruska (Los Alamos, New Mexico) |
| ABSTRACT | The present invention is directed to a process for preparing a solid composite having colloidal nanocrystals dispersed within a sol-gel matrix, the process including admixing colloidal nanocrystals with an amphiphilic polymer including hydrophilic groups selected from the group consisting of —COOH, —OH, —SO3H, —NH2, and —PO3H2 within a solvent to form an alcohol-soluble colloidal nanocrystal-polymer complex, admixing the alcohol-soluble colloidal nanocrystal-polymer complex and a sol-gel precursor material, and, forming the solid composite from the admixture. The present invention is also directed to the resultant solid composites and to the alcohol-soluble colloidal nanocrystal-polymer complexes. |
| FILED | Monday, November 17, 2003 |
| APPL NO | 10/715733 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Colloid systems and wetting agents; subcombinations thereof; processes of 516/98 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723463 | Fox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Robert V. Fox (Idaho Falls, Idaho); Recep Avci (Bozeman, Montana); Gary S. Groenewold (Idaho Falls, Idaho) |
| ABSTRACT | Methods of removing contaminant matter from porous materials include applying a polymer material to a contaminated surface, irradiating the contaminated surface to cause redistribution of contaminant matter, and removing at least a portion of the polymer material from the surface. Systems for decontaminating a contaminated structure comprising porous material include a radiation device configured to emit electromagnetic radiation toward a surface of a structure, and at least one spray device configured to apply a capture material onto the surface of the structure. Polymer materials that can be used in such methods and systems include polyphosphazine-based polymer materials having polyphosphazine backbone segments and side chain groups that include selected functional groups. The selected functional groups may include iminos, oximes, carboxylates, sulfonates, β-diketones, phosphine sulfides, phosphates, phosphites, phosphonates, phosphinates, phosphine oxides, monothio phosphinic acids, and dithio phosphinic acids. |
| FILED | Wednesday, April 12, 2006 |
| APPL NO | 11/279414 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 528/399 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723513 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Lianhe Yu (Raleigh, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Prathapan Sreedharan (Kerala, India); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | The present invention provides dipyrrin substituted porphyrinic macrocycles, intermediates useful for making the same, and methods of making the same. Such compounds may be used for purposes including the making of molecular memory devices, solar cells and light harvesting arrays. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 11/737979 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723643 | Hackel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); University of California (Davis, California) |
| INVENTOR(S) | Lloyd A. Hackel (Livermore, California); Tania M. Zaleski (Livermore, California); Hao-Lin Chen (Lafayette, California); Michael R. Hill (Davis, California); Kevin K. Liu (Newark, California) |
| ABSTRACT | A laser peening process for the densification of metal surfaces and sub-layers and for changing surface chemical activities provides retardation of the up-take and penetration of atoms and molecules, particularly Hydrogen, which improves the lifetime of such laser peened metals. Penetration of hydrogen into metals initiates an embrittlement that leaves the material susceptible to cracking. |
| FILED | Thursday, April 06, 2006 |
| APPL NO | 11/400618 |
| ART UNIT | 3742 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric heating 219/121.850 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724258 | Ebert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | David S. Ebert (Lafayette, Indiana); Joshua Schpok (Glendale, California) |
| ABSTRACT | 3D graphics animation is increasingly used in movies and virtual reality computer games to produce realistic visual simulations of physical and natural phenomena. The animation of diffuse liquids such as gases is an indispensable component in such special effects. The present system and methods utilize physically-based and more intuitive procedurally-based simulation techniques to simulate and render natural phenomena in computer graphics. The present invention facilitates user interaction in order to generate a variety of gas effects, for example, waves within water, plumes within hot gas, and flames within fire. Improved user interaction is achieved by improving rendering performance and introducing a new method of high-level control for Eulerian simulations. |
| FILED | Thursday, June 30, 2005 |
| APPL NO | 11/172098 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724733 | Benner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alan Frederic Benner (Poughkeepsie, New York); Cyriel Johan Agnes Minkenberg (Adliswil, Switzerland); Craig Brian Stunkel (Bethel, Connecticut) |
| ABSTRACT | The interconnecting network for switching data packets, having data and flow control information, comprises a local packet switch element (S1) with local input buffers (I(1,1) . . . I(1,y)) for buffering the incoming data packets, a remote packet switch element (S2) with remote input buffers (I(2,1) . . . I(2,y)) for buffering the incoming data packets, and data lines (L) for interconnecting the local and the remote packet switch elements (S1, S2). The interconnecting network further comprises a local and a remote arbiter (A1, A2) which are connected via control lines (CL) to the input buffers (I(1,1) . . . I(1,y), I(2,1) . . . I(2,y)), and which are formed such that they can provide that the flow control information is transmitted via the data lines (L) and the control lines (CL). |
| FILED | Thursday, March 31, 2005 |
| APPL NO | 11/095269 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/389 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724796 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Stephen Forrest (Ann Arbor, Michigan); Noel Giebink (Ann Arbor, Michigan) |
| ABSTRACT | A device comprising an organic light emitting layer may be optically pumped to create excited states within the layer. When an electric field is applied across the layer, the excited states may dissociate into geminate polaron pairs within the organic layer. The dissociated states may change back to excitons when the electric field is rapidly reduced or removed. The organic light emitting layer may be optically pumped by an adjacent OLED, allowing for an electrically-driven device. |
| FILED | Tuesday, August 29, 2006 |
| APPL NO | 11/511356 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/46.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725517 | Keenan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael R. Keenan (Albuquerque, New Mexico) |
| ABSTRACT | Several full-spectrum imaging techniques have been introduced in recent years that promise to provide rapid and comprehensive chemical characterization of complex samples. One of the remaining obstacles to adopting these techniques for routine use is the difficulty of reducing the vast quantities of raw spectral data to meaningful chemical information. Multivariate factor analysis techniques, such as Principal Component Analysis and Alternating Least Squares-based Multivariate Curve Resolution, have proven effective for extracting the essential chemical information from high dimensional spectral image data sets into a limited number of components that describe the spectral characteristics and spatial distributions of the chemical species comprising the sample. There are many cases, however, in which those constraints are not effective and where alternative approaches may provide new analytical insights. For many cases of practical importance, imaged samples are “simple” in the sense that they consist of relatively discrete chemical phases. That is, at any given location, only one or a few of the chemical species comprising the entire sample have non-zero concentrations. The methods of spectral image analysis of the present invention exploit this simplicity in the spatial domain to make the resulting factor models more realistic. Therefore, more physically accurate and interpretable spectral and abundance components can be extracted from spectral images that have spatially simple structure. |
| FILED | Thursday, September 22, 2005 |
| APPL NO | 11/233223 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/446 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07722752 | Schlenoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Florida State University Research Foundation (Tallahassee, Florida) |
| INVENTOR(S) | Joseph B. Schlenoff (Tallahassee, Florida); Zhijie Sui (Tucson, Arizona) |
| ABSTRACT | A microfluidic device for carrying a liquid, the device comprising a microfluidic channel having an interior wall and a polyelectrolyte film on the interior wall whereby liquid carried by the channel contacts the polyelectrolyte film, the polyelectrolyte film having a thickness of about 1 to about 1000 nanometers and comprising an interpenetrating network of a predominantly positively charged polymer and a predominantly negatively charged polymer, the predominantly positively charged polymer, the predominantly negatively charged polymer or both containing (i) a pH insensitive positively or negatively charged repeat unit having a pKa greater than 9 or less than 3, and (ii) a pH sensitive repeat unit, the pH sensitive repeat unit having a pKa of 3 to 9, whereby the pH of liquid in the microfluidic channel may be used to control the velocity or direction of electroosmotic flow of the liquid within said microfluidic channel. |
| FILED | Wednesday, March 02, 2005 |
| APPL NO | 11/070770 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722824 | Golovkina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Viktoriya N. Golovkina (Madison, Wisconsin); Franco Cerrina (Madison, Wisconsin) |
| ABSTRACT | Synthesis of arrays of chain molecules, such as oligonucleotides, in large quantities can be carried out utilizing projection onto an active substrate of a magnified image of a light emitting object array having selectable regions of light and dark areas forming a pattern. Projection optics formed entirely of mirrors are used to receive the light emitted from the object array and image the pattern of the array onto the active surface of the substrate. The mirrors in the projection optics include a first, concave mirror, a second, convex mirror, a third, concave mirror, and a fourth, convex mirror, each receiving the beam of light in turn, with the light reflected from the fourth mirror being imaged onto the active surface of the substrate with an image area greater than that of the original light emitting array. |
| FILED | Tuesday, August 01, 2006 |
| APPL NO | 11/497544 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722953 | Korgel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brian A. Korgel (Round Rock, Texas) |
| INVENTOR(S) | Brian A. Korgel (Round Rock, Texas); Keith P. Johnston (Austin, Texas) |
| ABSTRACT | A method for the production of a robust, chemically stable, crystalline, passivated nanoparticle and composition containing the same, that emit light with high efficiencies and size-tunable and excitation energy tunable color. The methods include the thermal degradation of a precursor molecule in the presence of a capping agent at high temperature and elevated pressure. A particular composition prepared by the methods is a passivated silicon nanoparticle composition displaying discrete optical transitions. |
| FILED | Thursday, October 07, 2004 |
| APPL NO | 10/959247 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723063 | Lauth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Intrinsic Lifesciences (La Jolla, California) |
| INVENTOR(S) | Xavier Lauth (San Diego, California); Mark E. Westerman (San Diego, California); Vaughn E. Ostland (La Quinta, California); Jason A. Stannard (San Diego, California); Michael W. Pennington (Mount Laurel, New Jersey) |
| ABSTRACT | The present invention concerns a method for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal; a method for measuring the level of hepcidin gene expression in a vertebrate animal; and a method for regulating the production of native, bioactive hepcidin in a vertebrate animal in vivo. The present invention also concerns an antibody or fragment thereof that specifically binds to a continuous, discontinuous, and/or conformational epitope of a mature and bioactive hepcidin folded as in the native configuration; and a pharmaceutical composition that includes the antibody or a hepcidin polypeptide and that provides antimicrobial, agonistic, or antagonistic activities in vivo in a vertebrate animal. |
| FILED | Thursday, April 28, 2005 |
| APPL NO | 11/119293 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.930 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723070 | Tirrell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David A. Tirrell (Pasadena, California); Kristi Lynn Kiick (Altadena, California) |
| ABSTRACT | Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallylglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine. |
| FILED | Monday, February 05, 2007 |
| APPL NO | 11/671378 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723109 | Lewis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Randolph V. Lewis (Laramie, Wyoming) |
| ABSTRACT | The present invention relates to the fields of molecular biology and plant biology. Specifically, the invention is directed to the methods for expressing spider silk proteins in plants and the synthesis and purification of spider silk proteins therefrom. |
| FILED | Monday, October 29, 2007 |
| APPL NO | 11/926871 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723255 | Hoveyda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Amir H. Hoveyda (Belmont, Massachusetts); Jason Kingsbury (Brookline, Massachusetts); Steven Garber (Brighton, Massachusetts); Brian Lawrence Gray (Chestnut Hill, Massachusetts); John T. Fourkas (Chestnut Hill, Massachusetts) |
| ABSTRACT | Highly active, recoverable and recyclable transition metal-based metathesis catalysts and their organometallic complexes including dendrimeric complexes are disclosed, including a Ru complex bearing a 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene and styrenyl ether ligand. The heterocyclic ligand significantly enhances the catalytic activity, and the styrenyl ether allows for the easy recovery of the Ru complex. Derivatized catalysts capable of being immobilized on substrate surfaces are also disclosed. The present catalysts can be used to catalyze ring-closing metathesis (RCM), ring-opening (ROM) and cross metatheses (CM) reactions, and promote the efficient formation of various trisubstituted olefins at ambient temperature in high yield. |
| FILED | Monday, July 11, 2005 |
| APPL NO | 11/178884 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/155 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723256 | Coates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Geoffrey W. Coates (Ithaca, New York); Zengquan Qin (Copley, Ohio); Claire Tova Cohen (Ithaca, New York) |
| ABSTRACT | Poly(propylene carbonates) are prepared from propylene oxide and CO2 with less than 10% cyclic propylene carbonate by product using cobalt based catalysts of structure preferably in combination with salt cocatalyst, very preferably cocatalyst where the cation is PPN+ and the anion is Cl− or OBzF5−. Novel products include poly(propylene carbonates) having a stereoregularity greater than 90% and/or a regioregularity of greater than 90%. |
| FILED | Monday, October 29, 2007 |
| APPL NO | 11/976800 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/167 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723262 | Feaver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | EnerG2, LLC (Seattle, Washington); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Aaron Feaver (Seattle, Washington); Guozhong Cao (Seattle, Washington) |
| ABSTRACT | Carbon cryogels, methods for making the carbon cryogels, methods for storing a gas using the carbon cryogels, and devices for storing and delivering a gas using the carbon cryogels. |
| FILED | Monday, November 21, 2005 |
| APPL NO | 11/284140 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/416 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723408 | Gerhardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Rosario A. Gerhardt (Marietta, Georgia); Runqing Qu (Roswell, Georgia); Zhi Li (Atlanta, Georgia); Robert J. Samuels (Atlanta, Georgia); Charles J. Capozzi (Alexandria, Virginia) |
| ABSTRACT | Composite materials are disclosed having low filler percolation thresholds for filler materials into the composite matrix material along with methods of controlling filler interconnectivity within the composite matrix material. Methods are, thus, disclosed that provide the ability to control the desired properties of the composites. The composites of the present disclosure are characterized by a “pseudo-crystalline” microstructure formed of matrix particles and filler particles where the matrix particles are faceted and substantially retain their individual particle boundaries and where the filler particles are interspersed between the matrix particles at the individual matrix particle boundaries such that the filler particles form a substantially interconnected network that substantially surrounds the individual faceted matrix particles. In an exemplary embodiment, the composites are formed by selecting matrix particles and filler particles wherein the ratio of the average size of the matrix particles to the average size of the filler particles is about 10 or more. The selected matrix particles exhibit a glass transition temperature. The matrix particles and the filler particles are mechanically mixed and then subjected to a temperature above the glass transition temperature of the matrix particles and a compression pressure for a period of time sufficient to cause the matrix particles to undergo deformation so as to compress them together eliminating void spaces between the particles without melting the matrix material. The method is also demonstrated to work in combination with more standard art methods such as solution mixing for the purposes of achieving additional control of the properties. |
| FILED | Thursday, February 16, 2006 |
| APPL NO | 11/357582 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 524/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724258 | Ebert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | David S. Ebert (Lafayette, Indiana); Joshua Schpok (Glendale, California) |
| ABSTRACT | 3D graphics animation is increasingly used in movies and virtual reality computer games to produce realistic visual simulations of physical and natural phenomena. The animation of diffuse liquids such as gases is an indispensable component in such special effects. The present system and methods utilize physically-based and more intuitive procedurally-based simulation techniques to simulate and render natural phenomena in computer graphics. The present invention facilitates user interaction in order to generate a variety of gas effects, for example, waves within water, plumes within hot gas, and flames within fire. Improved user interaction is achieved by improving rendering performance and introducing a new method of high-level control for Eulerian simulations. |
| FILED | Thursday, June 30, 2005 |
| APPL NO | 11/172098 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724373 | Glazier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | James A. Glazier (Bloomington, Indiana); Bogdan Dragnea (Bloomington, Indiana); Dragos Amarie (Bloomington, Indiana) |
| ABSTRACT | A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets. |
| FILED | Friday, December 15, 2006 |
| APPL NO | 11/611509 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724541 | Gracias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David H. Gracias (Baltimore, Maryland); Joe Tien (Brookline, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | Techniques for self assembly of macro-scale objects, optionally defining electrical circuitry, are described, as well as articles formed by self assembly. Components can be joined, during self-assembly by minimization of free energy, capillary attraction, or a combination. |
| FILED | Monday, February 13, 2006 |
| APPL NO | 11/352923 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Electrical systems and devices 361/810 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724738 | Chao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hung-Hsiang Jonathan Chao (Holmdel, New Jersey); Jinsoo Park (Leonia, New Jersey) |
| ABSTRACT | Packet-level multicasting may be used to avoid the cell header and the memory size problems. One or more multicast control cells may be appended before one or more data cells of a multicast packet to carry multicast bitmap information. The control cell may be stored at the cell memory. This approach is suitable for a multi-plane, multi-stage packet switch. |
| FILED | Friday, June 18, 2004 |
| APPL NO | 10/872187 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/390 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724782 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Xinyuan Wang (Clifton, Virginia); Shiping Chen (Dublin, California) |
| ABSTRACT | An interval centroid-based watermark encoder encodes a watermark into a packet flow. Intervals are defined for the packet flow. Some of the intervals are selected as group A intervals while other intervals are selected as group B intervals. Group A and group B intervals are paired and assigned to watermark bits. A first or second value may be encoded by increasing the relative packet time between packets in either the group A (for the first bit value) or group B (for the second bit value) interval(s) of the interval pair(s) assigned to the watermark bits that are to represent the first or second bit value and the beginning of the same group interval(s). The relative packet times may be measured by a decoder and used to calculate a centroid difference for each interval pair. The centroid differences may be used to reconstruct the watermark. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/051882 |
| ART UNIT | 2461 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/514 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724786 | Bouma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Brett Eugene Bouma (Quincy, Massachusetts); Seok-Hyun (Andy) Yun (Cambridge, Massachusetts); Wang-Yuhl (William) Oh (Cambridge, Massachusetts); Johannes F. De Boer (Somerville, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts) |
| ABSTRACT | An apparatus and source arrangement for filtering an electromagnetic radiation can be provided which may include at least one spectral separating arrangement configured to physically separate one or more components of the electromagnetic radiation based on a frequency of the electromagnetic radiation. The apparatus and source arrangement may also have at least one continuously rotating optical arrangement which is configured to receive at least one signal that is associated with the one or more components. Further, the apparatus and source arrangement can include at least one beam selecting arrangement configured to receive the signal. |
| FILED | Friday, April 11, 2008 |
| APPL NO | 11/867953 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07723234 | Babu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Clarkson University (Potsdam, New York); Infotonics Technology Center Inc. (Canandaigua, New York) |
| INVENTOR(S) | Suryadevara V. Babu (Potsdam, New York); Anita Natarajan (Potsdam, New York); Sharath Hegde (Portland, Oregon) |
| ABSTRACT | A method of removing polysilicon in preference to silicon dioxide and/or silicon nitride by chemical mechanical polishing. The method removes polysilicon from a surface at a high removal rate while maintaining a high selectivity of polysilicon to silicon dioxide and/or a polysilicon to silicon nitride. The method is particularly suitable for use in the fabrication of MEMS devices. |
| FILED | Wednesday, November 22, 2006 |
| APPL NO | 11/562443 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/693 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723464 | Delozier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Donovan M. Delozier (Newport News, Virginia); Kent A. Watson (New Kent, Virginia); John W. Connell (Yorktown, Virginia); Joseph G. Smith, Jr. (Smithfield, Virginia) |
| ABSTRACT | Novel compositions of matter comprise certain derivatives of 9,9-dialkyl fluorene diamine (AFDA). The resultant compositions, whether compositions of matter or monomers that are subsequently incorporated into a polymer, are unique and useful in a variety of applications. Useful applications of AFDA-based material include heavy ion radiation shielding components and components of optical and electronic devices. |
| FILED | Tuesday, February 13, 2007 |
| APPL NO | 11/674321 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 528/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724373 | Glazier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | James A. Glazier (Bloomington, Indiana); Bogdan Dragnea (Bloomington, Indiana); Dragos Amarie (Bloomington, Indiana) |
| ABSTRACT | A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets. |
| FILED | Friday, December 15, 2006 |
| APPL NO | 11/611509 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724423 | Bollond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alcatel-Lucent USA Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Paul Garry Bollond (Hamilton, New Jersey); Paul F. Wysocki (Flemington, New Jersey) |
| ABSTRACT | A method and apparatus for improved efficiency in optical fiber lasers. The system increases the efficiency of cladding pumped optical fiber amplifiers through a seeding technique which includes pumping an erbium/ytterbium doped fiber amplifier with pump energy, directing an optical signal through the erbium/ytterbium doped fiber amplifier, and seeding the optical signal with seed energy. The seed energy may have a higher energy level than the optical signal and a lower energy level than the pump energy, and the seed energy may be initially amplified in the amplifier and subsequently attenuated while amplifying the optical signal in the amplifier. |
| FILED | Thursday, March 16, 2006 |
| APPL NO | 11/377089 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optical: Systems and elements 359/341.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725169 | Boppart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Stephen A. Boppart (Champaign, Illinois); Chenyang Xu (Ayer, Massachusetts) |
| ABSTRACT | A method of forming an image of a sample includes performing SOCT on a sample. The sample may include a contrast agent, which may include an absorbing agent and/or a scattering agent. A method of forming an image of tissue may include selecting a contrast agent, delivering the contrast agent to the tissue, acquiring SOCT data from the tissue, and converting the SOCT data into an image. The contributions to the SOCT data of an absorbing agent and a scattering agent in a sample may be quantified separately. |
| FILED | Friday, April 14, 2006 |
| APPL NO | 11/405005 |
| ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725215 | Stange et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Kent Stange (Phoenix, Arizona); Richard Hess (Glendale, Arizona); Gerald B Kelley (Glendale, Arizona); Randy Rogers (Phoenix, Arizona) |
| ABSTRACT | A real-time multi-tasking digital control system with rapid recovery capability is disclosed. The control system includes a plurality of computing units comprising a plurality of redundant processing units, with each of the processing units configured to generate one or more redundant control commands. One or more internal monitors are employed for detecting data errors in the control commands. One or more recovery triggers are provided for initiating rapid recovery of a processing unit if data errors are detected. The control system also includes a plurality of actuator control units each in operative communication with the computing units. The actuator control units are configured to initiate a rapid recovery if data errors are detected in one or more of the processing units. A plurality of smart actuators communicates with the actuator control units, and a plurality of redundant sensors communicates with the computing units. |
| FILED | Thursday, May 04, 2006 |
| APPL NO | 11/381608 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07721662 | Way et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Thomas R. Way (Auburn, Alabama); Marlin R. Siegford (Opelika, Alabama); Dennis E. Rowe (Starkville, Mississippi) |
| ABSTRACT | The applicator system is designed to distribute agriculturally beneficial matter across a field. The system includes a supply reservoir and an agitator assembly that grates and abrades matter in the supply reservoir until the abraded matter precipitates out of the supply reservoir and onto a supply conveyor. The supply conveyor conveys the matter to a distribution device. The distribution device meters the matter onto at least two lateral distribution conveyors. At the end of each of the distribution conveyors the matter is funneled downwardly into an open trench created by a trenching device associated with each distribution conveyor. After the matter is deposited into the trench, a trench closing assembly directs soil back into the trench and compresses the soil surface. |
| FILED | Wednesday, June 18, 2008 |
| APPL NO | 12/214385 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Planting 111/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07721980 | Widmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Wilbur Widmer (Winter Haven, Florida); David Stewart (Boca Raton, Florida); Karel Grohmann (Davenport, Florida) |
| ABSTRACT | A method and apparatus for vacuum cooling heated viscous and/or high solids mixtures employs at least one cooling tank (1) having inwardly sloping side walls (15) from a top (14) to an opening that is attached to a outlet pump or valve (7) located at the tank bottom, a rotational spreader (8) near the top and at least one vacuum pump (5, 6) to maintain the predetermined vacuum in the tank, and input and output pumps (20, 21). The rotational spreader (8) breaks up the heated viscous and/or high solids mixture (9) and distributes it onto the side walls of the tank to form a film (10) which is cooled as it travels to and slides down the sides to the bottom where the viscous and/or high solids mixture is outputted from the tank by a pump or valve (7, 21, 26). Multiple stages of the apparatus may be employed preferably with progressively greater vacuum pressure in each stage to accomplish even further cooling of the viscous and/or high solids mixtures. |
| FILED | Tuesday, November 14, 2006 |
| APPL NO | 11/599056 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Solid material comminution or disintegration 241/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723565 | Amasino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Richard M. Amasino (Madison, Wisconsin); Si-Bum Sung (Madison, Wisconsin); Yuehui He (Madison, Wisconsin) |
| ABSTRACT | The invention provides vernalization-related polypeptides, nucleic acids and methods of using the same for inducibly-conferring epigenetic change on a target gene in plant or non-plant settings. |
| FILED | Friday, January 07, 2005 |
| APPL NO | 10/905520 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/278 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723584 | Coors et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James G. Coors (Madison, Wisconsin); Dustin T. Eilert (Mazomanie, Wisconsin); Patrick J. Flannery (Barneveld, Wisconsin) |
| ABSTRACT | According to the invention, there is provided seed and corn plants comprising brown midrib and gt1 genes conferring increased digestibility of plants and regrowth following cutting. The invention thus relates to corn plants, seeds and tissue cultures comprising brown midrib and gt1 genes, and to methods for producing a corn plant by crossing a corn plant comprising the brown midrib and gt1 genes with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants comprising brown midrib and gt1 genes with plants of another variety, such as an inbred line. |
| FILED | Wednesday, July 26, 2006 |
| APPL NO | 11/460076 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07722687 | Hampden-Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark J. Hampden-Smith (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); Plamen Atanassov (Albuquerque, New Mexico); Paolina Atanassova (Albuquerque, New Mexico); Klaus Kunze (Albuquerque, New Mexico); Paul Napolitano (Albuquerque, New Mexico); David Dericotte (Albuquerque, New Mexico); Rimple Bhatia (Albuquerque, New Mexico) |
| ABSTRACT | Energy devices such as batteries and methods for fabricating the energy devices. The devices are small, thin and lightweight, yet provide sufficient power for many handheld electronics. |
| FILED | Wednesday, June 14, 2006 |
| APPL NO | 11/424198 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Metal working 029/623.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07724782 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Xinyuan Wang (Clifton, Virginia); Shiping Chen (Dublin, California) |
| ABSTRACT | An interval centroid-based watermark encoder encodes a watermark into a packet flow. Intervals are defined for the packet flow. Some of the intervals are selected as group A intervals while other intervals are selected as group B intervals. Group A and group B intervals are paired and assigned to watermark bits. A first or second value may be encoded by increasing the relative packet time between packets in either the group A (for the first bit value) or group B (for the second bit value) interval(s) of the interval pair(s) assigned to the watermark bits that are to represent the first or second bit value and the beginning of the same group interval(s). The relative packet times may be measured by a decoder and used to calculate a centroid difference for each interval pair. The centroid differences may be used to reconstruct the watermark. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/051882 |
| ART UNIT | 2461 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/514 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07725531 | Sood et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Arun Sood (Clifton, Virginia); Yih Huang (Fairfax, Virginia); David Arsenault (Reston, Virginia) |
| ABSTRACT | A system and method for processing a client request using single use virtual servers. The method: receives the client request from a network; passes the client request to a new virtual incoming client request server; passes an application request from the virtual incoming client request server to a new virtual application server; destroys the virtual incoming client request server; passes an application result from the virtual application server to a new virtual outgoing client result server; destroys the new virtual application server; passes the application result from the new virtual outgoing client request server to the network; and destroys the virtual outgoing client request server. |
| FILED | Tuesday, September 18, 2007 |
| APPL NO | 11/857055 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/203 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07722858 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sudhir V. Shah (Little Rock, Arkansas); Alexei G. Basnakian (Little Rock, Arkansas); Yousri M. Barri (Richardson, Texas) |
| ABSTRACT | The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of measuring the level of cLDL and/or autoantibody to cLDL in a sample obtained from this individual. The invention further discloses a method of reducing carbamylation in an individual with a monomeric amino acid or other enzymatic or non-enzymatic inhibitors of carbamylation. The instant invention also provides a method to decrease the level of cLDL by direct elimination of cLDL from the blood or plasma of an individual. The invention also provides a method of treating or preventing atherosclerosis in an individual by inhibiting aggregation and/or deposition of cLDL in the individual. |
| FILED | Thursday, February 09, 2006 |
| APPL NO | 11/350660 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07723037 — Methods and kits for diagnosing or monitoring autoimmune and chronic inflammatory disease
| US 07723037 | Richardson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Bruce Richardson (Ann Arbor, Michigan); Qianjin Lu (Changsha, China PRC) |
| ABSTRACT | The present invention relates to compositions and methods for diagnosing, monitoring and/or treating an autoimmune or chronic inflammatory disease. In particular, the present invention provides methods for diagnosing, monitoring and treating an autoimmune disease (e.g., rheumatoid arthritis) or chronic inflammatory disease (e.g., systemic lupus erythematosus) based on detecting or altering (e.g., altering expression or methylation status of) autoimmune or chronic inflammatory disease proteins (e.g., CD70 and CD40L). The present invention also provides kits for detecting methylation status of autoimmune or chronic inflammatory disease proteins (e.g., CD70 and CD40L) and for diagnosing, monitoring and/or treating autoimmune or chronic inflammatory diseases. |
| FILED | Thursday, September 06, 2007 |
| APPL NO | 11/850897 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723328 | Longo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ABSTRACT | Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75NTR receptor molecule. Enhanced survival of neural and other cells has been observed. |
| FILED | Monday, April 03, 2006 |
| APPL NO | 11/396936 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/231.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 07724423 | Bollond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alcatel-Lucent USA Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Paul Garry Bollond (Hamilton, New Jersey); Paul F. Wysocki (Flemington, New Jersey) |
| ABSTRACT | A method and apparatus for improved efficiency in optical fiber lasers. The system increases the efficiency of cladding pumped optical fiber amplifiers through a seeding technique which includes pumping an erbium/ytterbium doped fiber amplifier with pump energy, directing an optical signal through the erbium/ytterbium doped fiber amplifier, and seeding the optical signal with seed energy. The seed energy may have a higher energy level than the optical signal and a lower energy level than the pump energy, and the seed energy may be initially amplified in the amplifier and subsequently attenuated while amplifying the optical signal in the amplifier. |
| FILED | Thursday, March 16, 2006 |
| APPL NO | 11/377089 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optical: Systems and elements 359/341.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07725267 | Prabhakarpandian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Balabhaskar Prabhakarpandian (Madison, Alabama); Shivshankar Sundaram (Madison, Alabama); Kapil Pant (Huntsville, Alabama) |
| ABSTRACT | The present invention is a synthetic microfluidic microvasculature network and associated methods. The synthetic microfluidic microvasculature network mimics the structure, fluid flow characteristics, and physiological behavior of physiological microvasculature networks. Computational methods for simulating flow and particle adherence in synthetic and physiological microvascular systems and methods for determining parameters influencing particle adhesion and drug delivery are also described. The invention has many uses including the optimization of drug delivery and microvascular treatments and in describing disease mechanisms that affect the microvasculature such as inflammation, diabetes and hypertension. |
| FILED | Friday, March 31, 2006 |
| APPL NO | 11/393715 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07722712 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Kaichang Li (Corvallis, Oregon) |
| ABSTRACT | A first variant of an adhesive composition for making a lignocellulosic composite includes soy protein and/or lignin; at least one substantially formaldehyde-free curing agent that includes at least one amine, amide, imine, imide, or nitrogen-containing heterocyclic functional group that can react with at least one functional group of the soy protein; and at least one compound selected from a boron compound, a group IA oxide or hydroxide, or a group IIA oxide or hydroxide. A second variant of an adhesive composition includes a first component selected from soy protein and/or lignin; and at least one substantially formaldehyde-free curing agent selected from a reaction product of epichlorohydrin with ethylenediamine, a reaction product of epichlorohydrin with bis-hexamethylenetriamine, or a reaction product of epichlorohydrin with hexamethylenediamine. |
| FILED | Wednesday, January 19, 2005 |
| APPL NO | 10/586623 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions: Coating or plastic 16/126.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07721601 | Yen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Packer Engineering, Inc. (Naperville, Illinois) |
| INVENTOR(S) | David W. Yen (Dayton, Ohio); JingYing Zhang (Kirkland, Washington); Peter J. Schubert (Naperville, Illinois) |
| ABSTRACT | A hydrogen storage tank for containing solid-state hydrogen storage media, and method for determining the hydrogen fill level in the tank. The tank has at least one compartment for storing the storage media, passages for transporting hydrogen gas to and from the compartment, and a heat distribution system for establishing a substantially uniform temperature in the storage media. A look-up table is generated for the tank that relates hydrogen pressure changes in the tank versus hydrogen fill levels in the tank as a function of temperature. The tank is filled to full capacity by adsorbing hydrogen on the storage media. Thereafter, hydrogen is released from the storage media for a time period during which there is a substantially constant demand on the tank, the change in pressure of the released hydrogen gas is measured, and the look-up table is applied to determine the hydrogen fill level in the tank. |
| FILED | Monday, June 18, 2007 |
| APPL NO | 11/764341 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/292 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07722279 | Neff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ITT Manufacturing Enterprises, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Todd Michael Neff (Salem, Virginia); Raymond Aguero (Roanoke, Virginia) |
| ABSTRACT | A molded plastic insert having a socket and groove formed on an outer surface to cooperate with spring loaded plungers on one of a pair of mating parts to couple the mating parts. A pair of indentations formed on the outer edge of the insert to accommodate any electrical leads between the mating parts. |
| FILED | Monday, November 26, 2007 |
| APPL NO | 11/944928 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Joints and connections 43/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723071 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher J. Evans (Los Angeles, California); Duane E. Keith, Jr. (Woodland Hills, California); Robert H. Edwards (Los Angeles, California); Daniel Kaufman (Santa Monica, California) |
| ABSTRACT | Recombinant forms of isolated and purified delta opioid receptors and methods to screen for compounds interactive with delta opioid receptors are described. |
| FILED | Friday, September 14, 2007 |
| APPL NO | 11/855971 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07723389 | Herzenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Leonard A. Herzenberg (Stanford, California); Leonore A. Herzenberg (Stanford, California); Stephen C. De Rosa (Seattle, Washington); James Andrus (Redwood City, California) |
| ABSTRACT | The invention provides pharmaceutical compositions for the treatment or prevention of the toxic effects of therapeutic agents and methods of treating or preventing such toxicity using a toxicity reducing amount of N-acetylcysteine either alone or in combination with a therapeutically effective amount or, to achieve its therapeutic advantages, an amount larger than what is customarily given as a therapeutically effective amount, of a therapeutic agent. The invention also provides pharmaceutical compositions for the treatment or prevention of the toxic effects of therapeutic agents and methods of treating or preventing such toxicity using a toxicity reducing amount of N-acetylcysteine either alone or in combination with a therapeutically effective amount or, to achieve its therapeutic advantages, an amount larger than what is customarily given as a therapeutically effective amount, of a therapeutic agent whose side effects are made worse by increased oxidative stress or treatment related decreases in subject cysteine/glutathione levels or are otherwise relieved by administration of NAC. |
| FILED | Monday, November 04, 2002 |
| APPL NO | 10/287175 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/562 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07725410 — Method, apparatus and system for aircraft deicing and estimating deicing completion times
| US 07725410 | Lee |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Transportation (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan Tuan Lee (Cambridge, Massachusetts) |
| ABSTRACT | The overall operating efficiency of processing objects, which are placed in a selected one of several available queues for subsequent processing at respective processing sites, is improved using a model relating the total time for processing to time of waiting in queue and processing. A deicing decision support tool uses the model for estimating completion times for deicing aircraft. |
| FILED | Thursday, April 06, 2006 |
| APPL NO | 11/398648 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 25, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100525.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page