FedInvent™ Patents
Patent Details for Tuesday, June 22, 2010
This page was updated on Monday, March 27, 2023 at 01:51 AM GMT
Department of Health and Human Services (HHS)
| US 07740840 | Zhan et al. |
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| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Chang-Guo Zhan (Lexington, Kentucky); Fang Zheng (Lexington, Kentucky); Wenchao Yang (Lexington, Kentucky) |
| ABSTRACT | Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (−)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (−)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration. |
| FILED | Monday, January 11, 2010 |
| APPL NO | 12/685341 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740845 | Cheung |
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| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Nai-Kong V. Cheung (Purchase, New York) |
| ABSTRACT | This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides different uses of the monoclonal antibody 8H9 or its derivative. |
| FILED | Thursday, March 06, 2003 |
| APPL NO | 10/505658 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740849 | Karumanchi et al. |
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| ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts); The Hospital for Sick Children (, Canada) |
| INVENTOR(S) | S. Ananth Karumanchi (Chestnut Hill, Massachusetts); Vikas P. Sukhatme (Newton, Massachusetts); Mourad Toporsian (Toronto, Canada); Michelle V. Letarte (Toronto, Canada) |
| ABSTRACT | Disclosed herein are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using combinations of compounds that alter soluble endoglin and sFlt-1 expression levels or biological activity. Also disclosed are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using compounds that increase endothelial nitric oxide synthase levels or biological activity. |
| FILED | Wednesday, May 31, 2006 |
| APPL NO | 11/443920 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740857 | Chakrabarty et al. |
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| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ananda Chakrabarty (Villa Park, Illinois); Tapas Das Gupta (River Forest, Illinois); Tohru Yamada (Oak Park, Illinois); Anita Chaudhari (Clifton Park, New York); Arsenio Fialho (Lisbon, Portugal); Chang Soo Hong (Chicago, Illinois) |
| ABSTRACT | The present invention relates to cupredoxin and cytochrome and their use, separately or together, to inhibit the spread of parasitemia in mammalian red blood cells and other tissues infected by the malaria parasite, and in particular the parasitemia of human red blood cells by P. falciparum. The invention provides isolated peptides that are variants, derivatives or structural equivalents of cupredoxins or cytochrome c, and compositions comprising cupredoxins and/or cytochrome c, or variants, derivatives or structural equivalents thereof, that are useful for treating or preventing malaria infection in mammals. Further, the invention provides methods to treat mammalian patients to prevent or inhibit the growth of malarial infection in mammals. The invention also provides methods to prevent the growth of malaria infection in insect vectors. |
| FILED | Monday, March 03, 2008 |
| APPL NO | 12/041411 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07740871 — Cancer immunotherapy with a viral antigen-defined, immunomodulator-secreting cell vaccine
| US 07740871 | Ambinder et al. |
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| ASSIGNEE(S) | Johns Hopkins University School of Medicine (Baltimore, Maryland) |
| INVENTOR(S) | Richard F. Ambinder (Lutherville, Maryland); Yiping Yang (Chapel Hill, North Carolina); Ivan M. Borrello (Baltimore, Maryland); Hyam I. Levitsky (Owing Mills, Maryland) |
| ABSTRACT | A human cell line, which lacks major histocompatibility class I (MHC-I) antigens and major histocompatibility class II (MHC-II) antigens and which has been modified to comprise and express (i) a nucleotide sequence encoding an immunomodulator and (ii) a nucleotide sequence encoding a viral antigen, and a method of inducing or stimulating an immune response in a human to a viral-associated disease or cancer comprising administering to the human (i) the aforementioned human cell line in an amount sufficient to induce or stimulate an immune response to the viral associated disease or cancer, (ii) a human cell line, which lacks MHC-I and MHC-11 antigens and which has been modified to comprise and express a nucleotide sequence encoding an immunomodulator, and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral-associated disease or cancer, or (iii) an immunomodulator and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral associated disease or cancer. |
| FILED | Friday, September 19, 2003 |
| APPL NO | 10/528311 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/277.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740880 | Kim et al. |
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| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Won Jong Kim (Salt Lake City, Utah); Sung Wan Kim (Salt Lake City, Utah) |
| ABSTRACT | A carrier for delivering small interfering RNA (siRNA) into cells includes a cholesterol residue covalently bonded to oligoarginine. Mixing the siRNA with the carrier produces a complex-containing composition. Contacting a cell with the complex-containing composition results in delivery of the siRNA into the cell. Delivery of an siRNA targeted to vascular endothelial growth factor is a treatment for cancer. Methods of making the carrier and complex are also disclosed. |
| FILED | Friday, March 03, 2006 |
| APPL NO | 11/367228 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741014 | Ryan et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Declan Ryan (Cahirdown, Ireland); Babak Amir-Parviz (Seattle, Washington); Vincent Linder (Renens, Switzerland); Vincent Semetey (Le Mans, France); Samuel K. Sia (New York, New York); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | A series of methods, compositions, and articles for patterning a surface with multiple, aligned layers of molecules, by exposing the molecules to electromagnetic radiation is provided. In certain embodiments, a single photomask acts as an area-selective filter for light at multiple wavelengths. A single set of exposures of multiple wavelengths through this photomask may make it possible to fabricate a pattern comprising discontinuous multiple regions, where the regions differ from each other in at least one chemical and/or physical property, without acts of alignment between the exposures. In certain embodiments, the surface includes molecules attached thereto that can be photocleaved upon exposure to a certain wavelength of radiation, thereby altering the chemical composition on at least a portion of the surface. |
| FILED | Monday, April 10, 2006 |
| APPL NO | 11/401485 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741021 | Burlingame et al. |
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| ASSIGNEE(S) | Regents of the University of California (Oakland, California); Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science (Rehovot, Israel) |
| INVENTOR(S) | Alma L. Burlingame (Sausalito, California); Katalin F. Medzihradszky (San Francisco, California); Zsuzsanna Darula (Boulder, Colorado); Eran Perlson (Givat Shmuel, Israel); Michael Fainzilber (Rehovot, Israel); Robert J. Chalkley (San Francisco, California); Darren Tyson (Aliso Viejo, California); Ralph A. Bradshaw (Lake Forest, California) |
| ABSTRACT | Post-translational O-sulfonation of a serine or threonine residue of proteins is detected, optionally comparatively, wherein the detected O-sulfonation is detected under a first physiological condition, and is compared with a control O-sulfonation detected under a second physiological condition, and a difference between the detected and control O-sulfonations indicates a difference between the first and second physiological conditions. Predetermined changes in physiological conditions are used to infer specific changes in O-sulfonation. Proteins are modified by introducing a predetermined change in O-sulfonation at a serine or threonine residue of the protein, and optionally, detecting a resultant change in O-sulfonation. These methods include introducing or increasing O-sulfonation, eliminating or reducing O-sulfonation; and derivatizing or substituting O-sulfonation. |
| FILED | Thursday, November 09, 2006 |
| APPL NO | 11/595319 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741022 | Porter et al. |
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| ASSIGNEE(S) | Wisconsin Alumi Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Frederick William Porter (Monona, Wisconsin); Ann Carol Palmenberg (Madison, Wisconsin); Christiane Wiese (Madison, Wisconsin); Yury Alexandrovitch Bochkov (Madison, Wisconsin) |
| ABSTRACT | The invention provides a method of inhibiting Ran protein activity in at least one eukaryotic cell or cell-free extract, the method comprising exposing an amino acid sequence comprising at least a portion of EMCV or TMEV leader protein, wherein the amino acid sequence comprises SEQ. ID NO: 14 or SEQ. ID NO: 15, to at least one cell in an amount effective to inhibit Ran activity in the targeted cell and evaluating Ran protein activity in the cell. |
| FILED | Thursday, January 18, 2007 |
| APPL NO | 11/654848 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741024 | Wyatt et al. |
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| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Richard T Wyatt (Rockville, Maryland); Joseph G Sodroski (Medford, Massachusetts); Tajib Mirzabekov (Palo Alto, California); Christoph Grundner (Oakland, California) |
| ABSTRACT | An immunogenic proteoliposome containing a transmembrane protein or oligomeric complexes containing such proteins, including viral envelope glycoproteins, in a lipid membrane around an elliptoid or spherical shape. The shape preferably also contains an attractant such as streptavidin or avidin and the lipid membrane contains a moiety that binds to the attractant such as biotin. The immunogenic transmembrane protein is bound to a ligand which is anchored in the shape. Methods for making the immunogenic proteoliposomes are provided. uses of the proteoliposome are described, including their use as immunogens to elicit immune reaction, and their use in screening assays, including their use as antigens to screen antibody libraries, as well as for drug screening and the identification of ligands. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 11/781998 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741032 | Evans et al. |
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| ASSIGNEE(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| INVENTOR(S) | William Edward Evans (Cordova, Tennessee); Mary Relling (Cordova, Tennessee); Qing Cheng (Memphis, Tennessee) |
| ABSTRACT | Single nucleotide polymorphisms (SNPs) in the gene encoding gamma glutamyl hydrolase (GGH) associated with reduced GGH activity are disclosed. The primary SNP is a change from a cytosine to a thymine at a position corresponding to nucleotide 511 of Genbank sequence accession no. NM 003878. Methods and kits for detecting these SNPs are provided, along with primers useful in detecting these SNP and for amplifying portions of the GGH gene containing these SNPs. |
| FILED | Thursday, July 08, 2004 |
| APPL NO | 10/887002 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741033 | Kelley et al. |
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| ASSIGNEE(S) | Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Shana Kelley (Boston, Massachusetts); Rahela Gasparac (Boston, Massachusetts); Melissa Lapierre-Devlin (Wakefield, Massachusetts); Bradford Taft (Medway, Massachusetts) |
| ABSTRACT | The detection of specific nucleic acid sequences using electrochemical readout would permit the rapid and inexpensive detection and identification of bacterial pathogens and the analysis of human genes. A new assay developed for this purpose is described that harnesses an electrocatalytic process to monitor nucleic acid hybridization. Furthermore, the new assay when used on nanoscale electrodes, provides ultrasensitive detection of nucleic acids. |
| FILED | Friday, August 06, 2004 |
| APPL NO | 10/913925 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741034 | Katz et al. |
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| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ruth Katz (Houston, Texas); Feng Jiang (Houston, Texas) |
| ABSTRACT | Gene probes for specific regions of chromosome 3 (3p21.3) and chromosome 10 (10q22) have been found to be tools for the diagnosis and prognosis of smoking related cancers such as non-small cell lung cancer (NSCLC). For example, these probes can be used with fluorescence in situ hybridization (FISH), and used to stratify smokers into high and low risk groups, as well as determine a patients susceptibility to the development of smoking related cancers. |
| FILED | Tuesday, September 28, 2004 |
| APPL NO | 10/952251 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741035 | Shaughnessy et al. |
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| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | John D. Shaughnessy (Little Rock, Arkansas); Bart Barlogie (Little Rock, Arkansas); Fenghuang Zhan (Little Rock, Arkansas) |
| ABSTRACT | Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to over-expression of genes such as ASPM, OPN3 and CKS1B which are located in chromosome 1q. Given the frequent amplification of 1q in many cancers, it is possible that these genes can be used as powerful prognostic markers and therapeutic targets for multiple myeloma and other cancer. |
| FILED | Wednesday, June 08, 2005 |
| APPL NO | 11/147829 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741040 | Markowitz |
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| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Sanford D. Markowitz (Pepper Pike, Ohio) |
| ABSTRACT | In certain aspects, the invention provides isolated SLC5A8 (also referred to as Hui1) nucleic acid molecules, which encode novel sodium solute symporter members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SLC5A8 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a SLC5A8 gene has been introduced or disrupted. The invention still further provides isolated SLC5A8 proteins, fusion proteins, antigenic peptides, and anti-SLC5A8 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. In other aspects, the invention provides methods and compositions for detecting and treating SLC5A8-associated cancer. Differential methylation of the SLC5A8 nucleotide sequences has been observed in SLC5A8-associated cancer, such as colon cancer, breast cancer, thyroid cancer, or stomach cancer. |
| FILED | Friday, July 07, 2006 |
| APPL NO | 11/484025 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741066 | Liu |
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| INVENTOR(S) | Zhi-Ren Liu (Atlanta, Georgia) |
| ABSTRACT | A method for determining the presence of cancer cells in a tissue sample or cell sample by detecting the presence of phosphorylated p68 RNA helicase in the sample. Further, a method for determining the presence of metastatic cancer cells in a tissue sample or cell sample by detecting the level of phosphorylated P68 RNA helicase in the sample such that a greater level of the phosphorylated protein in the sample as compared to non-metastatic cells is an indication of the metastatic cancer cells in the sample. |
| FILED | Friday, February 24, 2006 |
| APPL NO | 11/361258 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741071 | Zhang et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Zhiwen Zhang (San Diego, California); Lital Alfonta (San Diego, California); Peter Schultz (La Jolla, California) |
| ABSTRACT | This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation. |
| FILED | Thursday, December 16, 2004 |
| APPL NO | 10/580987 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741086 | Shi et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Yang Shi (Brookline, Massachusetts); Yujiang Shi (Boston, Massachusetts) |
| ABSTRACT | LSD1, a homolog of nuclear amine oxidases, functions as a histone demethylase and transcriptional co-repressor. LSD1 specifically demethylates histone H3 lysine 4, which is linked to active transcription. Lysine demethylation occurs via an oxidation reaction that generates formaldehyde. Importantly, RNAi inhibition of LSD1 causes an increase in H3 lysine 4 methylation and concomitant de-repression of target genes, suggesting that LSD1 represses transcription via histone demethylation. The results thus identify a histone demethylase conserved from S. pombe to human and reveal dynamic regulation of histone methylation by both histone methylases and demethylases. |
| FILED | Friday, December 16, 2005 |
| APPL NO | 11/721789 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741104 | Fulwyler et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mack J Fulwyler (Sarasota, Florida); Joe W Gray (San Francisco, California) |
| ABSTRACT | The invention provides methods and devices for detecting the presence of one or more target analytes in a sample employing a channel having affixed therein one or more binding partners for each target analyte. Assays are carried out by transporting the sample through the channel to each successive binding partner so that target analyte present in said sample binds to the corresponding binding partner. The sample is then transported beyond the binding partner(s), followed by detection of any target analyte bound to each binding partner. In one embodiment, binding efficiency is increased by the use of segmented transport, wherein a first bolus or bubble of a fluid that is immiscible with the sample precedes the sample during transport and a second bolus or bubble of a fluid that is immiscible with the sample follows the sample. Many configurations are possible for the device of the invention. A preferred device includes: a substrate with a channel formed in its surface, and a cover element that overlies and seals the channel. Binding partner(s) are affixed to the surface of the cover element facing the channel lumen. |
| FILED | Thursday, December 01, 2005 |
| APPL NO | 11/293047 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741111 | Chodosh et al. |
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| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Lewis A. Chodosh (West Chester, Pennsylvania); Heather P. Gardner (Carmel, California) |
| ABSTRACT | This invention relates generally to a novel CaM multi-functional protein kinase, which has been named Pregnancy Up-Regulated, Nonubiquitous CaM Kinase (PNCK), and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary development in a spatially heterogeneous manner in certain subsets of cells, and overexpressed in a subset of primary breast cancers. The invention further relates to an analysis of a correlation between carcinogenesis and postnatal development, particularly mammary development, especially associated with parity; as well as to methods of using the kinase, or gene encoding it, as markers, prognostic tools, screening tools and therapies, in vitro and in vivo that are based upon that correlation. |
| FILED | Monday, March 13, 2006 |
| APPL NO | 11/374353 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741112 | Khan |
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| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Shaharyar M. Khan (North Garden, Virginia) |
| ABSTRACT | The present invention provides compositions and methods for direct transfection of mitochondria and chloroplast DNA in living cells. More particularly, the present invention is based on the use of viral vectors that specifically bind to receptors uniquely found on the target organelle. In one embodiment, as shown in |
| FILED | Thursday, December 12, 2002 |
| APPL NO | 10/498328 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741116 | Boyce |
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| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio); Shriners Hospitals For Childrens (Tampa, Florida) |
| INVENTOR(S) | Steven T. Boyce (Cincinnati, Ohio) |
| ABSTRACT | A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin, and provides structures and functions as in normal uninjured skin, such as barrier function, which is a definitive property of normal skin. The device contains cultured dermal and epidermal cells on a biocompatible, biodegradable reticulated matrix. All or part of the cells may be autologous, from the recipient of the cultured skin device, which advantageously eliminates concerns of tissue compatibility. The cells may also be modified genetically to provide one or more factors to facilitate healing of the engrafted skin replacement, such as an angiogenic factor to stimulate growth of blood vessels. The inventive device is easy to handle and manipulate for surgical transplant, can be made into large sheets to minimize the number of grafts required to cover a large surface area to be treated, and can be produced within the time frame to treat a burned individual requiring a skin graft. |
| FILED | Wednesday, March 06, 2002 |
| APPL NO | 10/092237 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/347 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741130 | Lee, Jr. et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jessamine Lee, Jr. (Cambridge, Massachusetts); Rustem F. Ismagilov (Chicago, Illinois); Xingyu Jiang (Arlington, Massachusetts); Paul J. A. Kenis (Champaign, Illinois); Rosaria Ferrigno (Bron, France); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | The present invention relates to fluidic systems and, in particular, fluidic arrays and methods for using them to promote interaction of materials. In one embodiment, the present invention is directed to a microfluidic system. The microfluidic system includes a first fluid path and a second fluid path segregated from the first fluid path by a first convection controller at a first contact region, wherein at least one of the first fluid path and the second fluid path has a cross-sectional dimension of less than about 1 millimeter. In another aspect, the present invention is directed to a method of promoting interaction. In another aspect, the invention relates to a device and method for performing titrations. |
| FILED | Friday, February 20, 2004 |
| APPL NO | 10/783983 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/809 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741271 | Kuchroo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Vijay K. Kuchroo (Newton, Massachusetts); Sumone Chakravarti (Oakland, California); Terry Strom (Brookline, Massachusetts); Xin Xiao Zheng (Wellesley, Massachusetts); Jennifer Meyers (Brighton, Massachusetts) |
| ABSTRACT | The invention relates to methods of modulating immune responses in a subject, such as by administering to the subject agents which modulate tim-1, tim-2 or tim-4 activity, or which modulate the physical interaction between tim-1 and tim-4 or between tim-2 and a tim-2 ligand. Immune responses include, but are not limited to, autoimmune disorders, transplantation tolerance, and Th1 and Th2-mediated responses and disorders. The invention also relates to novel assays for identifying agents which modulate the physical interaction between tim-1 and tim-4. In addition, the invention relates to novel soluble tim-4 polypeptides and to nucleic acids which encode them. |
| FILED | Monday, March 14, 2005 |
| APPL NO | 11/080091 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741283 | Huang |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | St. Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Jung Huang (St. Louis, Missouri) |
| ABSTRACT | Disclosed are compositions and methods useful in the regulation of cell proliferation. The invention provides TGF-β (transforming growth factor β) and IGFBP-3 (insulin like growth factor binding protein 3) as ligands that engage LRP (low density lipoprotein receptor-related protein), heretofore known as TβR-V (TGF-β receptor V) and IGFBP-3 receptor, to effect a change in the phosphorylation and activation status of IRS (insulin receptor substrate) proteins. Compositions comprising TGF-β or IGFBP-3 and LRP or IRS protein are useful in the inhibition of cell proliferation and in the treatment of various diseases associated with unregulated cell proliferation. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/966371 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741290 | Mochly-Rosen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustee of The Leland Stanford Juinior University (Stanford, California) |
| INVENTOR(S) | Daria D. Mochly-Rosen (Menlo Park, California); Koichi K. Inagaki (Shiga, Japan) |
| ABSTRACT | Methods are described for slowing or inhibiting the progression of heart failure in a mammalian subject suffering from chronic hypertension. The methods involve administering an εPKC, β1PKC, or βIIPKC peptide inhibitor, examples of which are provided. |
| FILED | Friday, June 01, 2007 |
| APPL NO | 11/809521 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741295 | Schramm et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Vern L. Schramm (New Rochelle, New York); Jef D. Boeke (Baltimore, Maryland); Anthony Sauvé (Bronx, New York); Ivana Celic (Baltimore, Maryland) |
| ABSTRACT | A novel compound, 2′/3′-O-acetyl-ADP-ribose, is provided. The compound is a mixture of the 2′ and 3′ regioisomers of O-acetyl-ADP ribose, and is formed nonenzymatically from 2′-O-acetyl-ADP-ribose, which is the newly discovered product of the reaction of Sir2 enzymes with acetylated peptides and NAD+. Analogs of 2′/3′-O-acetyl-ADP-ribose are also provided. Additionally, methods of preparing 2′/3′-O-acetyl-ADP-ribose, methods of determining whether a test compound is an inhibitor of a Sir2 enzyme, methods of detecting Sir2 activity in a composition, methods of deacetylating an acetylated peptide, and methods of inhibiting the deacetylation of an acetylated peptide are provided. Prodrugs of 2′/3′-O-acetyl-ADP-ribose are also provided. |
| FILED | Friday, September 05, 2008 |
| APPL NO | 12/231880 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741298 | Altaba et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Ariel Ruiz i Altaba (New York, New York); Pilar Sanchez (Valencia, Spain); William Rom (Rye, New York); Kam-Meng Tchou Wong (New York, New York) |
| ABSTRACT | The present invention relates to compounds, small interfering RNAs and compositions and methods of inhibiting tumorigenesis using agents that inhibit the sonic hedgehog and GLI signaling pathway, including agents that inhibit GLI expression, synthesis and/or function. The present invention also relates to particular biomarkers that can be used in the diagnosis and prognosis of cancer. Methods of treating cancer, including glioblastomas, medulloblastomas, basal cell carcinomas, prostate cancer and small cell and non-small cell lung cancer are also provided using small organic compounds, siRNAs and blocking antibodies that inhibit or block the SHH/GLI pathway. |
| FILED | Tuesday, August 31, 2004 |
| APPL NO | 10/930723 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741300 | Dow et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | National Jewish Medical and Research Center (Denver, Colorado) |
| INVENTOR(S) | Steven W. Dow (Littleton, Colorado); Robyn E. Elmslie (Littleton, Colorado); Jurgen Karl Johannes Schwarze (Witten, Germany); Erwin W. Gelfand (Englewood, Colorado) |
| ABSTRACT | This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, an infectious disease, or a condition associated with a deleterious activity of a self-antigen. Also disclosed are therapeutic compositions useful in such a method. |
| FILED | Tuesday, December 27, 2005 |
| APPL NO | 11/320019 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741304 | Slaton et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of The University of Minnesota (Saint Paul, Minnesota) |
| INVENTOR(S) | Joel W. Slaton (Minneapolis, Minnesota); Khalil Ahmed (Minneapolis, Minnesota); Gretchen M. Unger (Chaska, Minnesota); Alan Davis (Lakeville, Minnesota); Dan Sloper (Maplewood, Minnesota) |
| ABSTRACT | The invention provides for antisense oligonucleotides that hybridize to casein kinase 2 nucleic acid sequences and methods of using such antisense oligonucleotides to inhibit expression of casein kinase 2 and reduce the size of solid tumors. |
| FILED | Thursday, June 14, 2007 |
| APPL NO | 11/763366 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741306 | Slack et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Frank J. Slack (Guilford, Connecticut); Steven M. Johnson (Redwood City, California); Helge Grosshans (Basel, Switzerland); Joanne Barnes Weidhaas (Westport, Connecticut) |
| ABSTRACT | Naturally occurring miRNAs that regulate human oncogenes and methods of use thereof are described. Suitable nucleic acids for use in the methods and compositions described herein include, but are not limited to, pri-miRNA, pre-miRNA, mature miRNA ,or fragments of variants thereof that retain the biological activity of the mature miRNA and DNA encoding a pri-miRNA, pre-miRNA, mature miRNA, fragments or variants thereof, or regulatory elements of the miRNA. The compositions are administered to a subject prior to administration of a cytotoxic therapy in an amount effective to sensitize cells or tissues to be treated to the effects of the cytotoxic therapy. |
| FILED | Monday, October 22, 2007 |
| APPL NO | 11/876503 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741307 | Sullenger et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Christopher P. Rusconi (Durham, North Carolina) |
| ABSTRACT | RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed. |
| FILED | Friday, October 26, 2007 |
| APPL NO | 11/925645 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741437 | Valenzuela et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); Merial Limited (Duluth, Georgia) |
| INVENTOR(S) | Jesus G. Valenzuela (Rockville, Maryland); Jose M. C. Ribiero (Rockville, Maryland); Shaden Kamhawi (Rockville, Maryland); Yasmine Belkaid (Norwood, Ohio); Laurent Fischer (Lyons, France); Jean-Christophe Audonnet (Lyons, France); Francis Milward (Bogart, Georgia) |
| ABSTRACT | Substantially purified salivary P. ariasi and P. perniciosus polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the P. ariasi and P. perniciosus polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating or preventing Leishmaniasis are disclosed. |
| FILED | Thursday, September 18, 2003 |
| APPL NO | 10/527500 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741446 | Pardridge et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Armagen Technologies, Inc. (Santa Monica, California) |
| INVENTOR(S) | William M. Pardridge (Pacific Palisades, California); Ruben J. Boado (Agoura Hills, California) |
| ABSTRACT | The invention provides diagnostic and therapeutic macromolecular compositions that cross the blood-brain barrier, in some embodiments in both directions, while allowing their activity to remain substantially intact once across the barrier. Also provided are methods for using such compositions in the diagnosis or treatment of CNS disorders such as Alzheimer's disease. |
| FILED | Monday, August 20, 2007 |
| APPL NO | 11/841623 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741456 | Khosla et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Chaitan Khosla (Palo Alto, California); Camilla M. Kao (Palo Alto, California) |
| ABSTRACT | Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method. |
| FILED | Monday, October 02, 2006 |
| APPL NO | 11/543267 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741458 | Ranum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Laura P. W. Ranum (St. Paul, Minnesota); Michael D. Koob (Roseville, Minnesota); Kellie A. Benzow (Plymouth, Minnesota); Melinda L. Moseley-Alldredge (St. Paul, Minnesota) |
| ABSTRACT | The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided. |
| FILED | Monday, February 24, 2003 |
| APPL NO | 10/373667 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741469 | Smith |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Richard J. Smith (Iowa City, Iowa) |
| ABSTRACT | This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of genes encoding proteins involved in deafness caused by dominant negative mechanism of action by RNA interference (RNAi) using small nucleic acid molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid, short interfering RNA, double-stranded RNA (dsRNA), micro-RNA (mRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of genes involved in deafness caused by dominant negative mechanism of action. |
| FILED | Wednesday, April 04, 2007 |
| APPL NO | 11/732619 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741520 | Brueggemeier et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Robert W Brueggemeier (Dublin, Ohio); Bin Su (Columbus, Ohio); Edgar S Diaz-Cruz (Columbus, Ohio); Serena Landini (Columbus, Ohio) |
| ABSTRACT | Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloalkyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alkyl, aryl, alkylaryl, arylalkyl, and cycloalkyl; R3, with the base nitrogen, forms an amide or sulfonamide; R4 is selected from nitro, amine, amide, and benzamide; or a pharmaceutically acceptable salts thereof. Also provided are small molecule selective aromatase inhibitors having a molecular weight of less 500 g/mol. In some embodiments, the small molecule selective aromatase inhibitors described herein have a molecular weight of less than 450 g/mol. Also provided are methods for suppressing aromatase activity expression in cancer cells comprising the step of administering a pharmaceutically effective amount of a small molecule aromatase inhibitor to a subject in need of such treatment. In one embodiment, the cancer cells are breast cancer cells. |
| FILED | Monday, February 05, 2007 |
| APPL NO | 11/702276 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741521 | Reed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | John C. Reed (Rancho Santa Fe, California); Maurizio Pellecchia (San Diego, California) |
| ABSTRACT | Various phenylamine derivatives are described as well as the use of compounds to inhibit BID protein for controlling apoptotic cascade. |
| FILED | Friday, December 22, 2006 |
| APPL NO | 11/645239 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741686 | Khuri-Yakub et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Butrus T. Khuri-Yakub (Palo Alto, California); Xuefeng Zhuang (Stanford, California); Arif Sanli Ergun (Mountain View, California) |
| ABSTRACT | A one or two-dimensional capacitive micro-machined ultrasonic transducer (CMUT) array with supporting frame is provided. The CMUT array has at least three array elements deposited on a conductive substrate. The invention also has at least one CMUT cell in the array element, a conductive top layer deposited to a top side of the element, and a conductive via disposed within the elements. The via is isolated from the conductive top layer and conducts with the substrate. There are at least two isolation trenches in the conductive substrate, and the trenches are disposed between adjacent vias to conductively isolating the vias. A substrate region between the trenches forms a mechanical support frame. At least one conductive electrode is deposited to a bottom surface of the conductive substrate, where the electrode conducts with the via. The support frame eliminates the need for a carrier wafer in the process steps. |
| FILED | Friday, July 20, 2007 |
| APPL NO | 11/880459 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/416 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742173 | Yun et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Seok-Hyun Yun (Cambridge, Massachusetts); Johannes F. De Boer (Somerville, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts) |
| ABSTRACT | Arrangements and methods are provided for obtaining data associated with a sample. For example, at least one first electro-magnetic radiation can be provided to a sample and at least one second electro-magnetic radiation can be provided to a reference (e.g., a non-reflective reference). A frequency of such radiation(s) can repetitively vary over time with a first characteristic period. In addition, a polarization state of the first electro-magnetic radiation, the second electro-magnetic radiation, a third electro-magnetic radiation (associated with the first radiation) or a fourth electro-magnetic radiation (associated with the second radiation) can repetitively vary over time with a second characteristic period which is shorter than the first period. The data for imaging at least one portion of the sample can be provided as a function of the polarization state. In addition or alternatively, the third and fourth electro-magnetic radiations can be combined so as to determine an axial reflectance profile of at least one portion of the sample. |
| FILED | Thursday, April 05, 2007 |
| APPL NO | 11/697012 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/479 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07739872 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Michael J. Murphy (Vernon, Connecticut); Jeffrey Lavin (Bloomfield, Connecticut); Jorge Farah (Glastonbury, Connecticut); Luis Coreano (Manchester, Connecticut); Henry Huizinga (Manchester, Connecticut); Andrew Burdick (East Hartford, Connecticut) |
| ABSTRACT | An example exhaust duct assembly includes a front liner, an intermediate liner and a rear liner. Each of the front, intermediate and rear liners include an inner liner exposed to combustion gases and an outer liner spaced radially apart from the inner liner. An air passage defined between the inner liner and the outer liner provides cooling air utilized for insulating an inner surface of the exhaust duct assembly. A closeout member is provided between the inner and outer liner and defines a portion of an air passage between the closeout member and the inner liner. Air flowing through the air passage is injected into a joint to provide cooling. The closeout member includes a horizontal leg that is bendable in a radial direction to accommodate relative movement between the inner liner and the outer liner. |
| FILED | Monday, February 14, 2005 |
| APPL NO | 11/057892 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/770 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07739921 | Babcock |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wade Babcock (Waldorf, Maryland) |
| ABSTRACT | A flow measurement system uses conduits adapted to be coupled to and throughout a liquid or gaseous fluid flow distribution system. Each conduit is instrumented to measure parameters associated with the liquid or gaseous fluid moving therethrough, and wireless transmit a unique code and data indicative of the parameters so-measured. A remotely-located receiver and output device(s) may be used to provide the data and unique code associated with each of the conduits in a human-discernable format. Each conduit may also receive data resulting in adjustment of fluid flow through the conduit. |
| FILED | Tuesday, August 21, 2007 |
| APPL NO | 11/900133 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/861.570 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07739938 | Nair et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael L. Nair (Rosedale, Maryland); John A. Condon (Timonium, Maryland) |
| ABSTRACT | The launching of an unmanned projectile includes pre-packaging a barrel with a projectile, a pusher cup, and a gas generator. The gas generator generates gas to propel the projectile out of the barrel. A pressure chamber increases a pressure of the gas in the barrel. The pressure chamber comprises a front body portion connected to the gas generator; an aft body portion connected to the front body portion and the gas generator; and a vent sleeve positioned around the front body portion and adapted to provide an aperture through which the gas exits the barrel in order to control a level of gas pressure in the barrel. A triggering of the gas generator causes the pusher cup to push the projectile out of the barrel at a predetermined launch velocity in order to attain a predetermined self-propelled flight trajectory, wherein the triggering causes the pusher cup to exit the barrel. |
| FILED | Saturday, September 15, 2007 |
| APPL NO | 11/856037 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07739953 | Laib |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gerald Laib (Olney, Maryland) |
| ABSTRACT | A method of making a thin film explosive detonator includes forming a substrate layer; depositing a metal layer in situ on the substrate layer; and reacting the metal layer to form a primary explosive layer. The method and apparatus formed thereby integrates fabrication of a micro-detonator in a monolithic MEMS structure using “in-situ” production of the explosive material within the apparatus, in sizes with linear dimensions below about 1 mm. The method is applicable to high-volume low-cost manufacturing of MEMS safety-and-arming devices. The apparatus can be initiated either electrically or mechanically at either a single point or multiple points, using energies of less than about 1 mJ. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/981304 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/202.140 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07739965 | Heinrichs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark Anthony Heinrichs (Brielle, New Jersey); Donald Edmund Fabula (Hazlet, New Jersey); Eric Robert Boyd (Ramsey, New Jersey) |
| ABSTRACT | Shipping and storage containers, racks, and pallets including automatic interlocking mechanisms are provided. An embodiment of the automatically locking pallet includes a pallet frame including a forklift tine opening, a pallet platform, a locking component movable into and out of a locking arrangement with an interface fitting of a storage assembly when the automatically locking pallet and the storage assembly are stacked, and an actuator operatively connected to the locking component. The actuator may be activated by a forklift tine entering the forklift tine opening to move the locking component out of the locking arrangement. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/387081 |
| ART UNIT | 3637 — Static Structures, Supports and Furniture |
| CURRENT CPC | Horizontally supported planar surfaces 18/53.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740104 | Parkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Red Tail Hawk Corporation (Ithaca, New York) |
| INVENTOR(S) | John W. Parkins (Ithaca, New York); John R. MacGillivray (Ithaca, New York) |
| ABSTRACT | A non-vented shell earplug for insertion into the ear canal has multiple chambers configured as coupled acoustic resonators. Each chamber is provided with an acoustic element having inertia and resistance coupling the chamber to its neighbor to form multiple resonant chambers. The dimensions of the individual acoustic elements set the frequency response of the earplug, and determine the attenuation characteristics of the resonators. Unlike the single chamber resonator of the prior art, the multiple-resonator earplug provides attenuation in both low and high frequency segments of the noise spectrum. Additionally, the present invention teaches placing loudspeaker and/or sound sensing transducer for sound communication purposes and active noise control within the earplug, with their sound field patterns directed into a chamber for coupling to the ear canal. The use of multiple resonators enhances the high frequency communications response of the earplug. |
| FILED | Wednesday, January 11, 2006 |
| APPL NO | 11/330300 |
| ART UNIT | 2832 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Acoustics 181/135 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740441 | Huber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Floride Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | David J Huber (Tequestra, Florida); Cheryl A Schopf (Jupiter, Florida); Jack W Wilson, Jr. (Palm Beach Gardens, Florida) |
| ABSTRACT | A small twin spool gas turbine engine with a bearing support arrangement in which the bearings are dampened by O-rings secured between the bearing races and the support structure, the bearings are arranged in series so that a cooling air can be passed through the bearings to prevent overheating, and the bearings are dry lubricated. The aft end of the engine includes high speed and low speed ball bearings supported with preload springs to add additional damping capability. The end bearing support assemblies form a cooling air path for the cooling fluid to flow through a passage within one of the guide vanes, through the bearings and a hole in the low pressure turbine rotor disk and out the exhaust of the engine. A snorkel tube extends into the bypass air channel drawing air for the bearings, and has a slanted opening preventing dirt particulates from entering the bearing cooling passage. |
| FILED | Friday, August 01, 2008 |
| APPL NO | 12/184729 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/112 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740442 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Ching-Pang Lee (Cincinnati, Ohio); Eric Alan Estill (Morrow, Ohio); James Harvey Laflen (Loveland, Ohio); Daniel Verner Jones (Fairfield, Ohio) |
| ABSTRACT | A method for cooling a shroud segment of a gas turbine engine includes providing a turbine shroud assembly including a shroud segment having a leading edge defining a forward face. A turbine nozzle is coupled to the turbine shroud assembly such that a gap is defined between an aft face of an outer band of the turbine nozzle and the forward face, wherein a lip formed on the aft face is positioned radially inwardly with respect to the gap and extends substantially axially downstream from the gap. Cooling air is directed into the gap. Cooling air exiting the gap impinges against the lip to facilitate film cooling the shroud segment. |
| FILED | Thursday, November 30, 2006 |
| APPL NO | 11/565447 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740444 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Ching-Pang Lee (Cincinnati, Ohio); James Harvey Laflen (Loveland, Ohio); Dustin Alfred Placke (Cincinnati, Ohio); George Elliott Moore (Lebanon, Ohio); Katherine Jaynetorrence Andersen (Cincinnati, Ohio); Daniel Verner Jones (Maineville, Ohio) |
| ABSTRACT | A method for cooling a turbine shroud assembly includes providing a turbine shroud assembly including a shroud segment having a leading edge, a trailing edge and a midsection defined therebetween. A shroud support circumferentially spans and supports the shroud segment. The shroud support includes a forward hanger coupled to the leading edge, a midsection hanger coupled to the midsection and an aft hanger coupled to the trailing edge. An annular shroud ring structure includes a midsection position control ring coupled to the midsection hanger and an aft position control ring coupled to the aft hanger. Cooling air is extracted from a compressor positioned upstream of the turbine shroud assembly. Cooling air is metered through the shroud support directly into only at least one active convection cooling zone defined between the shroud segment and the shroud support while substantially preventing cooling air from entering an inactive convection cooling zone positioned radially outwardly from the at least one active convection cooling zone and defined between the shroud support and the shroud ring structure and between the midsection position control ring and the aft position control ring. |
| FILED | Thursday, November 30, 2006 |
| APPL NO | 11/565387 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/173.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740821 | Watkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | James J. Watkins (South Hadley, Massachusetts); David M. Hess (Belchertown, Massachusetts) |
| ABSTRACT | A mesoporous silicate is prepared by a method that includes combining a silicate precursor, a bifunctional catalyst, and a structure-directing surfactant in an aqueous medium having a pH of about 4 to about 10. A mesoporous silicate forms as an aqueous suspension and can then be isolated. The mesoporous silicate can be formed under mild conditions of temperature and pH, and it exhibits a surprisingly high degree of network condensation. |
| FILED | Thursday, May 01, 2008 |
| APPL NO | 12/113336 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740960 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Dongming Zhu (Westlake, Ohio); Robert A. Miller (Brecksville, Ohio) |
| ABSTRACT | A multilayered coating system consisting of a multicomponent zirconia-base or hafnia-base oxide top layer, an interlayer comprised of a plurality of sublayers and a bond coat layer is provided. The multilayered coating system of the present invention, with an interlayer comprised of a plurality of sublayers, provides a protective coating solution for silicon-base ceramic components exposed to very high temperatures and/or high gas flow velocity water vapor combustion environments. The plurality of sublayers affords for a multitude of interfaces that aid in phonon scattering within the coating system and thereby reduces its thermal conductivity. Furthermore, the plurality of interlayer sublayers afford a strain tolerant buffer between the top layer and substrate and thereby accommodate the thermal expansion mismatch between the oxide top layer (coefficient of thermal expansion (CTE) up to ˜8-10×10−6 m/m-C) and the silicon-base ceramic substrate (CTE≈4-5×10−6 m/m-C). |
| FILED | Monday, August 28, 2006 |
| APPL NO | 11/510573 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/699 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740974 | Masel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Richard I. Masel (Champaign, Illinois); Robert Larsen (Urbana, Illinois); Su Yun Ha (Pullman, Washington) |
| ABSTRACT | An exemplary fuel cell of the invention includes a formic acid fuel solution in communication with an anode (12, 134), an oxidizer in communication with a cathode (16, 135) electrically linked to the anode, and an anode catalyst that includes Pd. An exemplary formic acid fuel cell membrane electrode assembly (130) includes a proton-conducting membrane (131) having opposing first (132) and second surfaces (133), a cathode catalyst on the second membrane surface, and an anode catalyst including Pd on the first surface. |
| FILED | Friday, November 05, 2004 |
| APPL NO | 10/578055 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741033 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Shana Kelley (Boston, Massachusetts); Rahela Gasparac (Boston, Massachusetts); Melissa Lapierre-Devlin (Wakefield, Massachusetts); Bradford Taft (Medway, Massachusetts) |
| ABSTRACT | The detection of specific nucleic acid sequences using electrochemical readout would permit the rapid and inexpensive detection and identification of bacterial pathogens and the analysis of human genes. A new assay developed for this purpose is described that harnesses an electrocatalytic process to monitor nucleic acid hybridization. Furthermore, the new assay when used on nanoscale electrodes, provides ultrasensitive detection of nucleic acids. |
| FILED | Friday, August 06, 2004 |
| APPL NO | 10/913925 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741036 | Ecker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ibis Biosciences, Inc. (Carlsbad, California) |
| INVENTOR(S) | David J. Ecker (Encinitas, California); Richard H. Griffey (Vista, California); Rangarajan Sampath (San Diego, California); Steven Hofstadler (Vista, California); John McNeil (La Jolla, California) |
| ABSTRACT | Method for detecting and identifying unknown bioagents, including bacteria, viruses and the like, by a combination of nucleic acid amplification and molecular weight determination using primers which hybridize to conserved sequence regions of nucleic acids derived from a bioagent and which bracket variable sequence regions that uniquely identify the bioagent. The result is a “base composition signature” (BCS) which is then matched against a database of base composition signatures, by which the bioagent is identified. |
| FILED | Friday, January 13, 2006 |
| APPL NO | 11/331978 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741111 | Chodosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Lewis A. Chodosh (West Chester, Pennsylvania); Heather P. Gardner (Carmel, California) |
| ABSTRACT | This invention relates generally to a novel CaM multi-functional protein kinase, which has been named Pregnancy Up-Regulated, Nonubiquitous CaM Kinase (PNCK), and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary development in a spatially heterogeneous manner in certain subsets of cells, and overexpressed in a subset of primary breast cancers. The invention further relates to an analysis of a correlation between carcinogenesis and postnatal development, particularly mammary development, especially associated with parity; as well as to methods of using the kinase, or gene encoding it, as markers, prognostic tools, screening tools and therapies, in vitro and in vivo that are based upon that correlation. |
| FILED | Monday, March 13, 2006 |
| APPL NO | 11/374353 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741146 | Cornfeld et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Emcore Solar Power, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Arthur Cornfeld (Sandia Park, New Mexico); Tansen Varghese (Albuquerque, New Mexico); Jacqueline Diaz (Albuquerque, New Mexico) |
| ABSTRACT | A method of forming a multifunction solar cell including an upper subcell, a middle subcell, and a lower subcell by providing a first substrate for the epitaxial growth of semiconductor material; forming a first solar subcell on the substrate having a first band gap; forming a second solar subcell over the first solar subcell having a second band gap smaller than the first band gap; forming a graded interlayer over the second subcell, the graded interlayer having a third band gap greater than the second band gap; forming a third solar subcell over the graded interlayer having a fourth band gap smaller than the second band gap such that the third subcell is lattice mismatched with respect to the second subcell; attaching a surrogate second substrate over the third solar subcell and removing the first substrate; and etching a first trough around the periphery of the solar cell to the surrogate second substrate so as to form a mesa structure on the surrogate second substrate and facilitate the removal of said solar cell from the surrogate second substrate. |
| FILED | Tuesday, August 12, 2008 |
| APPL NO | 12/190449 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/87 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741147 | Kiesel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Peter Kiesel (Palo Alto, California); Oliver Schmidt (Palo Alto, California) |
| ABSTRACT | A technique for creating high quality Schottky barrier devices in doped (e.g., Li+) crystalline metal oxide (e.g., ZnO) comprises field-controlled diffusion of mobile dopant atoms within the metal oxide crystal lattice. When heated (e.g., above 550 K) in the presence of an electric field (e.g., bias to ground of +/−50 V) the dopant atoms are caused to collect to form an ohmic contact, leaving a depletion region. The size of the depletion region controls the thickness of the Schottky barrier. Metal-semiconductor junction devices such as diodes, photo-diodes, photo-detectors, MESFETs, etc. may thereby be fabricated. |
| FILED | Friday, December 22, 2006 |
| APPL NO | 11/615331 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741431 | Allon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nahum Allon (Macabim, Israel); Carolyn Chambers (Adelphi, Maryland); Ashima Saxena (Fairfax, Virginia); Bhupendra P. Doctor (Potomac, Maryland) |
| ABSTRACT | A novel targeting peptide from the C-terminal of endothelin and/or a novel fusogenic peptide from hemagglutinin are optionally conjugated to the carboxy group of 1,2-dioleoyl-sn-glycero-3-succinate and incorporated into liposomes for therapeutic treatment. The novel targeting peptide directs liposomes to lung cells, and, therefore, is useful for delivering liposomes encapsulating cholinesterase genes, particularly, the human serum butyryl cholinesterase (Hu BChE) gene, as a treatment against nerve agents. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims. 37 CFR §1.72(b). |
| FILED | Wednesday, January 25, 2006 |
| APPL NO | 11/339404 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741503 | Wynne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James H Wynne (Alexandria, Virginia); Christopher T Lloyd (Springfield, Virginia); Joseph P. Buckley (Fairfax Station, Virginia); Ramesh R. Pant (Fairfax, Virginia); Brian T. Rasley (Fairbanks, Alaska) |
| ABSTRACT | A compound having the formula: Each R1 is C1-C3 alkyl group or fluoridated C1-C3 alkyl group. The value n is a positive integer. Each R2 is alkylene group or polyethylene glycol group. Y1 is hydrogen, quaternary ammonium-containing group, or phenol-containing group. Y2 is quaternary ammonium-containing group or phenol-containing group. The quaternary ammonium-containing group is non-aromatic and contains no more than one quaternary ammonium. |
| FILED | Wednesday, May 16, 2007 |
| APPL NO | 11/749252 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/425 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741557 | Cobb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Corning Incorporated (Corning, New York) |
| INVENTOR(S) | Joshua Monroe Cobb (Victor, New York); John H Bruning (Pittsford, New York) |
| ABSTRACT | An apparatus for obtaining energy from a polychromatic radiant energy source has a light concentrator for concentrating and redirecting incident radiant energy, having an optical axis, and a spectral separator disposed along the optical axis, apart from the light concentrator and in the path of concentrated, redirected radiant energy. The spectral separator has a first planar surface treated to reflect a first spectral band of light toward a first focal region and to transmit a second spectral band and a second planar surface spaced apart from the first planar surface and oblique with respect to the first planar surface. The second planar surface is treated to reflect the second spectral band back through the first planar surface and toward a second focal region spaced apart from the first focal region. First and second light receivers are disposed nearest each respective focal region for receiving the first and second spectral bands. |
| FILED | Thursday, August 03, 2006 |
| APPL NO | 11/498673 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/246 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741615 | Putterman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Seth Putterman (Los Angeles, California); James K. Gimzewski (Los Angeles, California); Brian B. Naranjo (Los Angeles, California) |
| ABSTRACT | Ferroelectric, pyroelectric and piezoelectric crystals are used to generate spatially localized high energy (up to and exceeding 100 keV) electron and ion beams, which may be used in a wide variety of applications including pulsed neutron generation, therapeutic X-ray/electron devices, elemental analysis, local scanning chemical analysis, high energy scanning microscopy, point source compact transmission electron microscopy, compact ion beam sources, positron sources, micro-thrusters for ion engines, and improved fusion efficiency especially of the Farnsworth type. The high-energy emission can be created by simply heating the material or by application of external coercive electromagnetic and acoustic fields. |
| FILED | Friday, April 22, 2005 |
| APPL NO | 11/596586 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/424 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741634 | Shim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Heejae Shim (Medford, New York); Jagadeesh S. Moodera (Somerville, Massachusetts) |
| ABSTRACT | A Josephson junction (JJ) device includes a buffered substrate comprising a first buffer layer formed on a substrate. A second buffer layer is formed on the first buffer layer. The second buffer layer includes a hexagonal compound structure. A trilayer structure is formed on the buffered substrate comprising at least two layers of a superconducting material. A thin tunnel barrier layer is positioned between the at least two layers. The buffered substrate is used to minimize lattice mismatch and interdiffusion in the trilayer structure so as to allow the JJ device to operate above 20 K. |
| FILED | Wednesday, March 26, 2008 |
| APPL NO | 12/055593 |
| ART UNIT | 2823 — Optics |
| CURRENT CPC | Active solid-state devices 257/36 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742000 | Mohamadi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Tialinx, Inc. (Irvine, California) |
| INVENTOR(S) | Farrokh Mohamadi (Irvine, California) |
| ABSTRACT | In one embodiment, an integrated circuit antenna array includes: a substrate, a plurality of first antennas adjacent a first side of the substrate; and an RF network adjacent a second side of the substrate, the RF feed network coupling to a distributed plurality of amplifiers integrated with the substrate and to a distributed plurality of phase-shifters also integrated with the substrate, each phase shifter being associated with a receptor to receive a beam-forming command, wherein each receptor is configured to receive the beam-forming command through either a near-field coupling or a far-field coupling. |
| FILED | Wednesday, October 18, 2006 |
| APPL NO | 11/550789 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/700.MS0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742327 | Chuang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ching Te Chuang (South Salem, New York); Jae-Joon Kim (Yorktown Heights, New York); Keunwoo Kim (Somers, New York) |
| ABSTRACT | Techniques are provided for back-gate control in an asymmetrical memory cell. In one aspect, the cell includes five transistors and can be employed for static random access memory (SRAM) applications. An inventive memory circuit can include a plurality of bit line structures, a plurality of word line structures that intersect the plurality of bit line structures to form a plurality of cell locations, and a plurality of cells located at the plurality of cell locations. Each cell can be selectively coupled to a corresponding one of the bit line structures under control of a corresponding one of the word line structures. Each cell can include a first inverter having first and second field effect transistors (FETS) and a second inverter with third and fourth FETS that is cross-coupled to the first inverter to form a storage flip-flop. One of the FETS in the first inverter can be configured with independent front and back gates and can function as both an access transistor and part of one of the inverters. |
| FILED | Wednesday, November 05, 2008 |
| APPL NO | 12/265042 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742415 | Davé |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nikhil Davé (San Diego, California) |
| ABSTRACT | A determination of latency in IP networks is performed by sensing packets, determining a status of the sensed packets and comparing original packets with acknowledgements (ACKs). A packet header on a physical layer interface (e.g., int 0) is sensed. A determination is made of a sensed packet status. If the packet is sensed, a hashed record of the packet header is created, including a local clock time of when the packet was sensed. A determination is made as to whether the packet represents an ACK to a previously sensed TCP packet. If the packet represents an ACK to a previously sensed packet, a time delay between the previous sensing of the packet and the ACK is calculated. The time delay is the TCP ACK Round Trip Time (TCP RTT). |
| FILED | Wednesday, September 26, 2007 |
| APPL NO | 11/862094 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742597 | Lewis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | James M. Lewis (Moulton, Alabama) |
| ABSTRACT | An encryption system includes a plurality of encryption operations including individual encryption operations and group encryption operations available for application in the encryption of data. The plurality of encryption operations are selected from the group consisting of functional variance, functional alignment, mathematical offset, wide XOR function, short logical rotation, long logical rotation, functional order, and address encryption. The system includes at least one round of encryption composed of a first encryption operation and a second encryption operation. The first encryption operation is selected from the plurality of encryption operations acting upon input data to generate a first encrypted data set. The second encryption operation is selected from the plurality of encryption operations acting upon the first encrypted data set to generate a second encrypted data set. The first encryption operation and the second encryption operation are different. |
| FILED | Friday, December 28, 2007 |
| APPL NO | 12/003557 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Cryptography 380/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07739911 | Panetta |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Paul D. Panetta (Richland, Washington) |
| ABSTRACT | Using an ultrasonic field, properties of a solid liquid suspension such as through-transmission attenuation, backscattering, and diffuse field are measured. These properties are converted to quantities indicating the strength of different loss mechanisms (such as absorption, single scattering and multiple scattering) among particles in the suspension. Such separation of the loss mechanisms can allow for direct comparison of the attenuating effects of the mechanisms. These comparisons can also indicate a model most likely to accurately characterize the suspension and can aid in determination of properties such as particle size, concentration, and density of the suspension. |
| FILED | Friday, September 15, 2006 |
| APPL NO | 11/532484 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/599 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07739994 | Mcgilvray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Andrew N. Mcgilvray (East Peoria, Illinois); John T. Vachon (Peoria, Illinois); William E. Moser (Peoria, Illinois) |
| ABSTRACT | An internal combustion engine that includes a block, a cylinder head having an intake valve port and exhaust valve port formed therein, a piston, and a combustion chamber defined by the block, the piston, and the head. At least one thermoelectric device is positioned within either or both the intake valve port and the exhaust valve port. Each of the valves is configured to move within a respective intake and exhaust valve port thereby causing said valves to engage the thermoelectric devices resulting in heat transfer from the valves to the thermoelectric devices. The intake valve port and exhaust valve port are configured to fluidly direct intake air and exhaust gas, respectively, into the combustion chamber and the thermoelectric device is positioned within the intake valve port, and exhaust valve port, such that the thermoelectric device is in contact with the intake air and exhaust gas. |
| FILED | Monday, May 14, 2007 |
| APPL NO | 11/803402 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/193.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740362 | Neil et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Jefferson Science Associates (Newport News, Virginia) |
| INVENTOR(S) | George R. Neil (Williamsburg, Virginia); Michelle D. Shinn (Newport News, Virginia) |
| ABSTRACT | A radius of curvature controlled mirror for controlling precisely the focal point of a laser beam or other light beam. The radius of curvature controlled mirror provides nearly spherical distortion of the mirror in response to differential expansion between the front and rear surfaces of the mirror. The radius of curvature controlled mirror compensates for changes in other optical components due to heating or other physical changes. The radius of curvature controlled mirror includes an arrangement for adjusting the temperature of the front surface and separately adjusting the temperature of the rear surface to control the radius of curvature. The temperature adjustment arrangements can include cooling channels within the mirror body or convection of a gas upon the surface of the mirror. A control system controls the differential expansion between the front and rear surfaces to achieve the desired radius of curvature. |
| FILED | Tuesday, February 19, 2008 |
| APPL NO | 12/070522 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/845 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740424 | Pardini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Allan F. Pardini (Kennewick, Washington); Kevin L. Gervais (Richland, Washington); Royce A. Mathews (Kennewick, Washington); Ronald L. Hockey (Richland, Washington) |
| ABSTRACT | An apparatus and method are disclosed for separating articles from a group of articles. The apparatus includes a container for containing one or more articles coupled to a suitable fluidizer for suspending articles within the container and transporting articles to an induction tube. A portal in the induction tube introduces articles singly into the induction tube. A vacuum pulls articles through the induction tube separating the articles from the group of articles in the container. The apparatus and method can be combined with one or more unit operations or modules, e.g., for inspecting articles, assessing quality of articles, or ascertaining material properties and/or parameters of articles, including layers thereof. |
| FILED | Wednesday, February 15, 2006 |
| APPL NO | 11/355608 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Conveyors: Fluid current 46/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740845 | Cheung |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Nai-Kong V. Cheung (Purchase, New York) |
| ABSTRACT | This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides different uses of the monoclonal antibody 8H9 or its derivative. |
| FILED | Thursday, March 06, 2003 |
| APPL NO | 10/505658 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740902 | O'Brien et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | 3M Innovative Properties Company (Saint Paul, Minnesota) |
| INVENTOR(S) | Dennis P. O'Brien (Maplewood, Minnesota); Alison K. Schmoeckel (Stillwater, Minnesota); George D. Vernstrom (Cottage Grove, Minnesota); Radoslav Atanasoski (Edine, Minnesota); Thomas E. Wood (Stillwater, Minnesota); David G. O'Neill (Lake Elmo, Minnesota) |
| ABSTRACT | Methods are provided for making oxygen-reducing catalyst layers, which include simultaneous or sequential stops of physical vapor depositing an oxygen-reducing catalytic material onto a substrate, the catalytic material comprising a transition metal that is substantially free of platinum; and thermally treating the catalytic material. At least one of the physical vapor deposition and the thermal treatment is performed in a processing environment comprising a nitrogen-containing gas. |
| FILED | Thursday, April 20, 2006 |
| APPL NO | 11/379518 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740916 | Grunow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | EUV LLC. (Santa Clara, California) |
| INVENTOR(S) | Philip A. Grunow (San Leandro, California); Wayne M. Clift (Tracy, California); Leonard E. Klebanoff (San Clemente, California) |
| ABSTRACT | A coating for the protection of optical surfaces exposed to a high energy erosive plasma. A gas that can be decomposed by the high energy plasma, such as the xenon plasma used for extreme ultraviolet lithography (EUVL), is injected into the EUVL machine. The decomposition products coat the optical surfaces with a protective coating maintained at less than about 100 Å thick by periodic injections of the gas. Gases that can be used include hydrocarbon gases, particularly methane, PH3 and H2S. The use of PH3 and H2S is particularly advantageous since films of the plasma-induced decomposition products S and P cannot grow to greater than 10 Å thick in a vacuum atmosphere such as found in an EUVL machine. |
| FILED | Monday, April 05, 2004 |
| APPL NO | 10/818586 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/569 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740948 | Alvin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Mary Anne Alvin (Pittsburg, Pennsylvania) |
| ABSTRACT | This disclosure addresses the issue of providing a metallic-ceramic overlay coating that potentially serves as an interface or bond coat layer to provide enhanced oxidation resistance to the underlying superalloy substrate via the formation of a diffusion barrier regime within the supporting base material. Furthermore, the metallic-ceramic coating is expected to limit the growth of a continuous thermally grown oxide (TGO) layer that has been primarily considered to be the principal cause for failure of existing TBC systems. Compositional compatibility of the metallic-ceramic with traditional yttria-stabilized zirconia (YSZ) top coats is provided to further limit debond or spallation of the coating during operational use. A metallic-ceramic architecture is disclosed wherein enhanced oxidation resistance is imparted to the surface of nickel-based superalloy or single crystal metal substrate, with simultaneous integration of the yttria stabilized zirconia (YSZ) within the metallic-ceramic overlayer. |
| FILED | Thursday, May 31, 2007 |
| APPL NO | 11/756049 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/469 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740966 | Jacobson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Craig P. Jacobson (Lafayette, California); Steven J. Visco (Berkeley, California); Lutgard C. De Jonghe (Lafayette, California) |
| ABSTRACT | Multiple stacks of tubular electrochemical cells having a dense electrolyte disposed between an anode and a cathode preferably deposited as thin films arranged in parallel on stamped conductive interconnect sheets or ferrules. The stack allows one or more electrochemical cell to malfunction without disabling the entire stack. Stack efficiency is enhanced through simplified gas manifolding, gas recycling, reduced operating temperature and improved heat distribution. |
| FILED | Wednesday, August 30, 2006 |
| APPL NO | 11/512521 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/31 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740974 | Masel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Richard I. Masel (Champaign, Illinois); Robert Larsen (Urbana, Illinois); Su Yun Ha (Pullman, Washington) |
| ABSTRACT | An exemplary fuel cell of the invention includes a formic acid fuel solution in communication with an anode (12, 134), an oxidizer in communication with a cathode (16, 135) electrically linked to the anode, and an anode catalyst that includes Pd. An exemplary formic acid fuel cell membrane electrode assembly (130) includes a proton-conducting membrane (131) having opposing first (132) and second surfaces (133), a cathode catalyst on the second membrane surface, and an anode catalyst including Pd on the first surface. |
| FILED | Friday, November 05, 2004 |
| APPL NO | 10/578055 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741071 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Zhiwen Zhang (San Diego, California); Lital Alfonta (San Diego, California); Peter Schultz (La Jolla, California) |
| ABSTRACT | This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation. |
| FILED | Thursday, December 16, 2004 |
| APPL NO | 10/580987 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741074 | Lopez de Leon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Alfredo Lopez de Leon (Davis, California); Michael Rey (Davis, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Wednesday, December 03, 2008 |
| APPL NO | 12/327509 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741084 | Viitanen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | E. I. du Pont de Nemours and Company (Wilmington, Delaware); Alliance for Sustainable Energy LLC (Golden, Colorado) |
| INVENTOR(S) | Paul V. Viitanen (West Chester, Pennsylvania); Carol M. McCutchen (Wilmington, Delaware); Mark Emptage (Wilmington, Delaware); Perry G. Caimi (Kennett Square, Pennsylvania); Min Zhang (Lakewood, Colorado); Yat-Chen Chou (Lakewood, Colorado) |
| ABSTRACT | Production of ethanol using a strain of xylose-utilizing Zymomonas with a genetic modification of the glucose-fructose oxidoreductase gene was found to be improved due to greatly reduced production of xylitol, a detrimental by-product of xylose metabolism synthesized during fermentation. |
| FILED | Thursday, September 27, 2007 |
| APPL NO | 11/862736 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/161 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741119 | Viitanen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | E. I. du Pont de Nemours and Company (Wilmington, Delaware); Alliance for Sustainable Energy LLC (Golden, Colorado) |
| INVENTOR(S) | Paul V. Viitanen (West Chester, Pennsylvania); Yat-Chen Chou (Lakewood, Colorado); Carol M. McCutchen (Wilmington, Delaware); Min Zhang (Lakewood, Colorado) |
| ABSTRACT | A strain of xylose-utilizing Zymomonas was engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation under process-relevant conditions. |
| FILED | Thursday, September 27, 2007 |
| APPL NO | 11/862566 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/440 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741120 | Klimov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Victor I. Klimov (Los Alamos, New Mexico); Jennifer A. Hollingsworth (Los Alamos, New Mexico); Scott A. Crooker (Los Alamos, New Mexico); Hyungrak Kim (Albuquerque, New Mexico) |
| ABSTRACT | Multifunctional nanocomposites are provided including a core of either a magnetic material or an inorganic semiconductor, and, a shell of either a magnetic material or an inorganic semiconductor, wherein the core and the shell are of differing materials, such multifunctional nanocomposites having multifunctional properties including magnetic properties from the magnetic material and optical properties from the inorganic semiconductor material. Various applications of such multifunctional nanocomposites are also provided. |
| FILED | Tuesday, August 28, 2007 |
| APPL NO | 11/897073 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741225 | Rohatgi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ajeet Rohatgi (Marietta, Georgia); Vichai Meemongkolkiat (Atlanta, Georgia) |
| ABSTRACT | A thin silicon solar cell having a back dielectric passivation and rear contact with local back surface field is described. Specifically, the solar cell may be fabricated from a crystalline silicon wafer having a thickness from 50 to 500 micrometers. A barrier layer and a dielectric layer are applied at least to the back surface of the silicon wafer to protect the silicon wafer from deformation when the rear contact is formed. At least one opening is made to the dielectric layer. An aluminum contact that provides a back surface field is formed in the opening and on the dielectric layer. The aluminum contact may be applied by screen printing an aluminum paste having from one to 12 atomic percent silicon and then applying a heat treatment at 750 degrees Celsius. |
| FILED | Tuesday, May 06, 2008 |
| APPL NO | 12/116132 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741353 | Huynh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | My Hang V. Huynh (Los Alamos, New Mexico) |
| ABSTRACT | Lead-free primary explosives of the formula (cat)Y[MII(T)X(H2O)6-X]Z, where T is 5-nitrotetrazolate, and syntheses thereof are described. Substantially stoichiometric equivalents of the reactants lead to high yields of pure compositions thereby avoiding dangerous purification steps. |
| FILED | Tuesday, May 15, 2007 |
| APPL NO | 11/803839 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/381 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741428 | Kong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Peter C. Kong (Idaho Falls, Idaho) |
| ABSTRACT | A method for producing a borohydride is described that includes the steps of providing a source of borate; providing a material that chemically reduces the source of the borate to produce a borohydride; and reacting the source of the borate and the material by supplying heat at a temperature that substantially effects the production of the borohydride. |
| FILED | Thursday, August 21, 2008 |
| APPL NO | 12/196134 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 528/394 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741466 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Kimberly Brown (Elk Grove, California); Paul Harris (Carnation, Washington); Elizabeth Zaretsky (Reno, Nevada); Edward Re (Davis, California); Elena Vlasenko (Davis, California); Keith McFarland (Davis, California); Alfredo Lopez de Leon (Davis, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. |
| FILED | Friday, March 21, 2008 |
| APPL NO | 12/053193 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741486 | Boyle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Timothy J Boyle (Albuquerque, New Mexico) |
| ABSTRACT | A water soluble, water stable, titanium alkoxide composition represented by the chemical formula (OC6H6N)2Ti(OC6H2(CH2N(CH3)2)3-2,4,6)2 with a theoretical molecular weight of 792.8 and an elemental composition of 63.6% C, 8.1% H, 14.1% N, 8.1% O and 6.0% Ti. |
| FILED | Wednesday, March 18, 2009 |
| APPL NO | 12/406449 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741577 | Kong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Peter C. Kong (Idaho Falls, Idaho); Jon D. Grandy (Idaho Falls, Idaho); Brent A. Detering (Idaho Falls, Idaho) |
| ABSTRACT | A device, method and system for generating a plasma is disclosed wherein an electrical arc is established and the movement of the electrical arc is selectively controlled. In one example, modular units are coupled to one another to collectively define a chamber. Each modular unit may include an electrode and a cathode spaced apart and configured to generate an arc therebetween. A device, such as a magnetic or electromagnetic device, may be used to selectively control the movement of the arc about a longitudinal axis of the chamber. The arcs of individual modules may be individually controlled so as to exhibit similar or dissimilar motions about the longitudinal axis of the chamber. In another embodiment, an inlet structure may be used to selectively define the flow path of matter introduced into the chamber such that it travels in a substantially circular or helical path within the chamber. |
| FILED | Tuesday, March 28, 2006 |
| APPL NO | 11/392141 |
| ART UNIT | 3742 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electric heating 219/121.360 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741613 | Mascarenhas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Livermore, California) |
| INVENTOR(S) | Nicholas Mascarenhas (Livermore, California); Peter Marleau (Dublin, California); James S. Brennan (Rodeo, California); Kevin D. Krenz (Livermore, California) |
| ABSTRACT | An instrument that will directly image the fast fission neutrons from a special nuclear material source has been described. This instrument can improve the signal to background compared to non imaging neutron detection techniques by a factor given by ratio of the angular resolution window to 4π. In addition to being a neutron imager, this instrument will also be an excellent neutron spectrometer, and will be able to differentiate between different types of neutron sources (e.g. fission, alpha-n, cosmic ray, and D-D or D-T fusion). Moreover, the instrument is able to pinpoint the source location. |
| FILED | Wednesday, September 24, 2008 |
| APPL NO | 12/237251 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/390.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742564 | Parham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Brookhaven Science Associates (Upton, New York); The University of Saskatchewan (Saskatoon, Saskatchewan, Canada) |
| INVENTOR(S) | Christopher Parham (Raleigh, North Carolina); Zhong Zhong (Stony Brook, New York); Etta Pisano (Chapel Hill, North Carolina); Dean Connor (Shirley, New York); Leroy D. Chapman (Saskatoon, Canada) |
| ABSTRACT | Systems and methods for detecting an image of an object using an X-ray beam having a polychromatic energy distribution are disclosed. According to one aspect, a method can include detecting an image of an object. The method can include generating a first X-ray beam having a polychromatic energy distribution. Further, the method can include positioning a single monochromator crystal in a predetermined position to directly intercept the first X-ray beam such that a second X-ray beam having a predetermined energy level is produced. Further, an object can be positioned in the path of the second X-ray beam for transmission of the second X-ray beam through the object and emission from the object as a transmitted X-ray beam. The transmitted X-ray beam can be directed at an angle of incidence upon a crystal analyzer. Further, an image of the object can be detected from a beam diffracted from the analyzer crystal. |
| FILED | Wednesday, January 24, 2007 |
| APPL NO | 11/657391 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/71 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742640 | Carlson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey J. Carlson (Albuquerque, New Mexico); Michael K. Giles (Las Cruces, New Mexico); Denise D. Padilla (Albuquerque, New Mexico); Patrick A. Davidson, Jr. (Albuquerque, New Mexico); David K. Novick (Albuquerque, New Mexico); Christopher W. Wilson (Albuquerque, New Mexico) |
| ABSTRACT | Methods for segmenting the reflected light of an illumination source having a characteristic wavelength from background illumination (i.e. clutter) in structured lighting systems can comprise pulsing the light source used to illuminate a scene, pulsing the light source synchronously with the opening of a shutter in an imaging device, estimating the contribution of background clutter by interpolation of images of the scene collected at multiple spectral bands not including the characteristic wavelength and subtracting the estimated background contribution from an image of the scene comprising the wavelength of the light source and, placing a polarizing filter between the imaging device and the scene, where the illumination source can be polarized in the same orientation as the polarizing filter. Apparatus for segmenting the light of an illumination source from background illumination can comprise an illuminator, an image receiver for receiving images of multiple spectral bands, a processor for calculations and interpolations, and a polarizing filter. |
| FILED | Friday, October 13, 2006 |
| APPL NO | 11/580572 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07740821 | Watkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | James J. Watkins (South Hadley, Massachusetts); David M. Hess (Belchertown, Massachusetts) |
| ABSTRACT | A mesoporous silicate is prepared by a method that includes combining a silicate precursor, a bifunctional catalyst, and a structure-directing surfactant in an aqueous medium having a pH of about 4 to about 10. A mesoporous silicate forms as an aqueous suspension and can then be isolated. The mesoporous silicate can be formed under mild conditions of temperature and pH, and it exhibits a surprisingly high degree of network condensation. |
| FILED | Thursday, May 01, 2008 |
| APPL NO | 12/113336 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740826 | Khabashesku et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Valery N. Khabashesku (Houston, Texas); Haiqing Peng (Houston, Texas); John L. Margrave (Bellaire, Texas); Mary Lou Margrave, legal representative (Bellaire, Texas); Wilbur Edward Billups (Houston, Texas); Yunming Ying (Houston, Texas) |
| ABSTRACT | A method for functionalizing the wall of single-wall or multi-wall carbon nanotubes involves the use of acyl peroxides to generate carbon-centered free radicals. The method allows for the chemical attachment of a variety of functional groups to the wall or end cap of carbon nanotubes through covalent carbon bonds without destroying the wall or endcap structure of the nanotube. Carbon-centered radicals generated from acyl peroxides can have terminal functional groups that provide sites for further reaction with other compounds. Organic groups with terminal carboxylic acid functionality can be converted to an acyl chloride and further reacted with an amine to form an amide or with a diamine to form an amide with terminal amine. The reactive functional groups attached to the nanotubes provide improved solvent dispersibility and provide reaction sites for monomers for incorporation in polymer structures. The nanotubes can also be functionalized by generating free radicals from organic sulfoxides. |
| FILED | Tuesday, October 24, 2006 |
| APPL NO | 11/585368 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741022 | Porter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumi Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Frederick William Porter (Monona, Wisconsin); Ann Carol Palmenberg (Madison, Wisconsin); Christiane Wiese (Madison, Wisconsin); Yury Alexandrovitch Bochkov (Madison, Wisconsin) |
| ABSTRACT | The invention provides a method of inhibiting Ran protein activity in at least one eukaryotic cell or cell-free extract, the method comprising exposing an amino acid sequence comprising at least a portion of EMCV or TMEV leader protein, wherein the amino acid sequence comprises SEQ. ID NO: 14 or SEQ. ID NO: 15, to at least one cell in an amount effective to inhibit Ran activity in the targeted cell and evaluating Ran protein activity in the cell. |
| FILED | Thursday, January 18, 2007 |
| APPL NO | 11/654848 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741091 | DeAngelis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma); Wei Jing (Edmond, Oklahoma) |
| ABSTRACT | The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella multocida, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure. |
| FILED | Thursday, January 25, 2007 |
| APPL NO | 11/698311 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741130 | Lee, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jessamine Lee, Jr. (Cambridge, Massachusetts); Rustem F. Ismagilov (Chicago, Illinois); Xingyu Jiang (Arlington, Massachusetts); Paul J. A. Kenis (Champaign, Illinois); Rosaria Ferrigno (Bron, France); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | The present invention relates to fluidic systems and, in particular, fluidic arrays and methods for using them to promote interaction of materials. In one embodiment, the present invention is directed to a microfluidic system. The microfluidic system includes a first fluid path and a second fluid path segregated from the first fluid path by a first convection controller at a first contact region, wherein at least one of the first fluid path and the second fluid path has a cross-sectional dimension of less than about 1 millimeter. In another aspect, the present invention is directed to a method of promoting interaction. In another aspect, the invention relates to a device and method for performing titrations. |
| FILED | Friday, February 20, 2004 |
| APPL NO | 10/783983 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/809 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741475 | Fraser-Reid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Natural Products and Glycotechnology Research Institute, Inc. (Fearrington, North Carolina) |
| INVENTOR(S) | Bertram Fraser-Reid (Pittsboro, North Carolina); Jun Lu (Cary, North Carolina) |
| ABSTRACT | The present application provides arabinans and mannose-capped arabinan compositions of formulas I-VIII, described herein, and methods of making the compositions. |
| FILED | Tuesday, February 13, 2007 |
| APPL NO | 11/674287 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/123 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741734 | Joannopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
| ABSTRACT | The electromagnetic energy transfer device includes a first resonator structure receiving energy from an external power supply. The first resonator structure has a first Q-factor. A second resonator structure is positioned distal from the first resonator structure, and supplies useful working power to an external load. The second resonator structure has a second Q-factor. The distance between the two resonators can be larger than the characteristic size of each resonator. Non-radiative energy transfer between the first resonator structure and the second resonator structure is mediated through coupling of their resonant-field evanescent tails. |
| FILED | Wednesday, July 05, 2006 |
| APPL NO | 11/481077 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical transmission or interconnection systems 37/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741936 | Weller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Thomas Weller (Lutz, Florida); Balaji Lakshminarayanan (Tampa, Florida); Srinath Balachandran (Tampa, Florida) |
| ABSTRACT | The present invention provides a monolithic inductor developed using radio frequency micro electromechanical (RF MEMS) techniques. In a particular embodiment of the present invention, a tunable radio frequency microelectromechanical inductor includes a coplanar waveguide and a direct current actuatable contact switch positioned to vary the effective width of a narrow inductive section of the center conductor of the CPW line upon actuation the DC contact switch. In a specific embodiment of the present invention, the direct current actuatable contact switch is a diamond air-bridge integrated on an alumina substrate to realize an RF switch in the CPW and microstrip topology. |
| FILED | Tuesday, September 04, 2007 |
| APPL NO | 11/849703 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742504 | Zimmermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Roger Zimmermann (Walnut, California); Cyrus Shahabi (Irvine, California); Kun Fu (Los Angeles, California); Shu-Yuen Didi Yao (Los Angeles, California) |
| ABSTRACT | Systems and techniques for transmitting data stream to a client include transmitting a data segment from one of a plurality of nodes of a continuous media server to a client according to a scheduler on the node. A system includes a plurality of data processing devices, each data processing device coupled with at least one storage device. Each data processing device includes a scheduler to schedule transmission of the data segment to a client in sequence with other data segments, and a module to transmit the data segment to the client. |
| FILED | Friday, January 24, 2003 |
| APPL NO | 10/351461 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/487 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742662 | Cunningham |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Brian T. Cunningham (Champaign, Illinois) |
| ABSTRACT | Photonic crystal (PC) sensors, and sensor arrays and sensing systems incorporating PC sensors are described which have integrated fluid containment and/or fluid handling structures. Sensors and sensing systems of the present disclosure are capable of high throughput sensing of analytes in fluid samples, bulk refractive index detection, and label-free detection of a range of molecules, including biomolecules and therapeutic candidates. The present disclosure also provides a commercially attractive fabrication platform for making photonic crystal sensors and systems wherein an integrated fluid containment structure and a photonic crystal structure are fabricated in a single molding or imprinting processing step amendable to high throughput processing. |
| FILED | Tuesday, November 06, 2007 |
| APPL NO | 11/983109 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742664 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Vescent Photonics, Inc. (Denver, Colorado) |
| INVENTOR(S) | Michael H. Anderson (Lyons, Colorado); Scott D. Rommel (Lakewood, Colorado); Scott R. Davis (Denver, Colorado) |
| ABSTRACT | Liquid crystal waveguides for dynamically controlling the refraction of light. Generally, liquid crystal materials may be disposed within a waveguide in a cladding proximate or adjacent to a core layer of the waveguide. In one example, portions of the liquid crystal material can be induced to form refractive or lens shapes in the cladding that interact with a portion (e.g. evanescent) of light in the waveguide so as to permit electronic control of the refraction/bending, focusing, or defocusing of light as it travels through the waveguide. In one example, a waveguide may be formed using one or more patterned or shaped electrodes that induce formation of such refractive or lens shapes of liquid crystal material, or alternatively, an alignment layer may have one or more regions that define such refractive or lens shapes to induce formation of refractive or lens shapes of the liquid crystal material. In another example, such refractive or lens shapes of liquid crystal material may be formed by patterning or shaping a cladding to define a region or cavity to contain liquid crystal material in which the liquid crystal materials may interact with the evanescent light. |
| FILED | Tuesday, October 12, 2004 |
| APPL NO | 10/963946 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Optical waveguides 385/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07740864 | Cain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Kenneth D. Cain (Moscow, Idaho); Benjamin R. LaFrentz (Auburn, Alabama); Scott LaPatra (Twin Falls, Idaho) |
| ABSTRACT | Fish are immunized by a mass vaccination method, such as by immersion in water containing an attenuated strain of a pathogenic bacterium that does not effectively cause disease in fish when the non-attenuated pathogenic bacterium is exposed to the fish by immersion. An illustrative example of the method is for immunizing against coldwater disease caused by Flavobacterium psychrophilum, which may be attenuated by serial passage in media containing increasing amounts of an antibiotic, such as rifampicin. |
| FILED | Monday, June 02, 2008 |
| APPL NO | 12/156509 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/200.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740867 | Barletta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Raul G. Barletta (Lincoln, Nebraska); N. Beth Harris (Lincoln, Nebraska) |
| ABSTRACT | Disclosed are methods for the determination of virulence determinants in bacteria and in particular bacteria of the genus Mycobacterium. Also disclosed are compositions and methods for stimulating an immune response in an animal using bacteria and virulence determinants identified by the methods of the present invention. |
| FILED | Tuesday, November 27, 2007 |
| APPL NO | 11/945770 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/234.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740889 | Stern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); State Research Center for Applied Microbiology and Biotechnology, Ministry of Health and Social Development, RF, as represented by Director of the State Research Center for Applied Microbiology and Biotechnology, Ministry of Health and Social Development, RF (Obolensk, Russian Federation) |
| INVENTOR(S) | Norman J Stern (Athens, Georgia); Edward A Svetoch (Serpukhov District, Russian Federation); Boris V Eruslanov (Serpukhov District, Russian Federation); Vladimir V Perelygin (Serpukhov District, Russian Federation); Vladimir P Levchuk (Serpukhov District, Russian Federation); Nikolay N Urakov (Olympic vill., Russian Federation); Larisa I Volodina (Serpukhov District, Russian Federation); Yuri N. Kovalev (Serpukhov District, Russian Federation); Tamara Y. Kudryavtseva (Serpukhov District, Russian Federation); Victor D. Pokhilenko (Serpukhov District, Russian Federation); Valery N. Borzenkov (Serpukhov District, Russian Federation); Olga E. Svetoch (Serpukhov District, Russian Federation); Eugeni V. Mitsevich (Serpukhov District, Russian Federation); Irina P. Mitsevich (Serpukhov District, Russian Federation) |
| ABSTRACT | Novel bacteriocins produced by novel bacterial strains are used for at least reducing the levels of colonization by at least one target bacteria in animals, especially poultry. |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859166 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Food or edible material: Processes, compositions, and products 426/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741058 | Sutovsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Peter Sutovsky (Columbia, Missouri); Antonio Miranda-Vizuete (Sevilla, Spain) |
| ABSTRACT | The present invention concerns compositions and methods for evaluating fertility in humans and animals. The invention may also be used to identify reproductive cancers such as testicular cancer. In various embodiments of the invention, an Sptrx-3 enzyme is used as a fertility marker. Sptrx-3 may be detected in accordance with the invention in vitro or in vivo. |
| FILED | Friday, July 25, 2008 |
| APPL NO | 12/180290 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741063 | Hill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Dolores Hill (Hague, Virginia); Dante S Zarlenga (Ellicott City, Maryland); Cathleen Coss (Catonsville, Maryland); Jitender P Dubey (Greenbelt, Maryland) |
| ABSTRACT | Recombinant proteins have been developed for the detection of Toxoplasma gondii oocyst proteins for example in biological fluids. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins. |
| FILED | Wednesday, May 06, 2009 |
| APPL NO | 12/436596 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741438 | Steele et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Utah State University (Logan, Utah) |
| INVENTOR(S) | James L. Steele (Middleton, Wisconsin); Jeffrey R. Broadbent (Smithfield, Utah); Vidya R. Sridhar (Portland, Oregon) |
| ABSTRACT | The present invention concerns the methods and compositions involving endopeptidase enzymes, especially PepO2 and PepO3 from L. helveticus, and their use in reducing bitterness by cleaving bitter peptides. In particular embodiments of the invention, these methods and compositions apply to the cheesemaking process. The invention also concerns the use of PepO2 and/or PepO3 polypeptides in the treatment or prevention of celiac sprue or as a food additive. |
| FILED | Monday, June 21, 2004 |
| APPL NO | 10/873427 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP21089 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Greenwood, Florida) |
| INVENTOR(S) | Zhanao Deng (Ellenton, Florida); Brent Harbaugh (Bradenton, Florida) |
| ABSTRACT | A new Caladium plant named ‘75-14’ particularly distinguished by its heart-shaped leaves with a white center, green margins, and numerous purple spots, and demonstrated potential to produce high tuber yield, develop attractive and sun-tolerant plants in outdoor sunny landscapes, and produce attractive pot plants when tubers are forced in containers, is disclosed. |
| FILED | Thursday, December 18, 2008 |
| APPL NO | 12/317018 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07739899 | Holland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Stephen D. Holland (Ames, Iowa); Dale E. Chimenti (Ames, Iowa); Ronald A. Roberts (Ames, Iowa) |
| ABSTRACT | A method for detection and location of air leaks in a pressure vessel, such as a spacecraft, includes sensing structure-borne ultrasound waveforms associated with turbulence caused by a leak from a plurality of sensors and cross correlating the waveforms to determine existence and location of the leak. Different configurations of sensors and corresponding methods can be used. An apparatus for performing the methods is also provided. |
| FILED | Friday, April 28, 2006 |
| APPL NO | 11/413523 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/40.5R0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07739918 | LaPeyronnie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Louisiana) |
| INVENTOR(S) | Glenn M. LaPeyronnie (Gretna, Louisiana); Charles M. Huff (Slidel, Louisiana) |
| ABSTRACT | The present invention provides a testing apparatus and method for testing the adhesion of a coating to a surface. The invention also includes an improved testing button or dolly for use with the testing apparatus and a self aligning button hook or dolly interface on the testing apparatus. According to preferred forms, the apparatus and method of the present invention are simple, portable, battery operated rugged, and inexpensive to manufacture and use, are readily adaptable to a wide variety of uses, and provide effective and accurate testing results. The device includes a linear actuator driven by an electric motor coupled to the actuator through a gearbox and a rotatable shaft. The electronics for the device are contained in the head section of the device. At the contact end of the device, is positioned a self aligning button hook, attached below the load cell located on the actuator shaft. |
| FILED | Thursday, February 21, 2008 |
| APPL NO | 12/035259 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/827 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740088 | Bar-Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Yoseph Bar-Cohen (Seal Beach, California); Mircea Badescu (Arcadia, California); Stewart Sherrit (La Crescenta, California); Xiaoqi Bao (San Gabriel, California); Steve Kassab (Hennosa Beach, California) |
| ABSTRACT | A mechanism for drilling or coring by a combination of sonic hammering and rotation. The drill includes a hammering section with a set of preload weights mounted atop a hammering actuator and an axial passage through the hammering section. In addition, a rotary section includes a motor coupled to a drive shaft that traverses the axial passage through the hammering section. A drill bit is coupled to the drive shaft for drilling by a combination of sonic hammering and rotation. The drill bit includes a fluted shaft leading to a distal crown cutter with teeth. The bit penetrates sampled media by repeated hammering action. In addition, the bit is rotated. As it rotates the fluted bit carries powdered cuttings helically upward along the side of the bit to the surface. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 11/928069 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Boring or penetrating the earth 175/415 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742663 | Buckley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | John D. Buckley (Newport News, Virginia); William C. Edwards (Poquoson, Virginia); Warren C. Kelliher (Hampton, Virginia); Ingrid A. Carlberg (Yortown, Virginia) |
| ABSTRACT | A wave energy transmission apparatus has a conduit made from a refractory oxide. A transparent, refractory ceramic window is coupled to the conduit. Wave energy passing through the window enters the conduit. |
| FILED | Thursday, October 30, 2008 |
| APPL NO | 12/261376 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742845 | Fink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Wolfgang Fink (Montrose, California); James Dohm (Chandler, Arizona); Mark A. Tarbell (Walnut, California) |
| ABSTRACT | A method of controlling a plurality of crafts in an operational area includes providing a command system, a first craft in the operational area coupled to the command system, and a second craft in the operational area coupled to the command system. The method further includes determining a first desired destination and a first trajectory to the first desired destination, sending a first command from the command system to the first craft to move a first distance along the first trajectory, and moving the first craft according to the first command. A second desired destination and a second trajectory to the second desired destination are determined and a second command is sent from the command system to the second craft to move a second distance along the second trajectory. |
| FILED | Tuesday, January 10, 2006 |
| APPL NO | 11/330077 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07742854 | Fussell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Boeing Management Company (Irvine, California) |
| INVENTOR(S) | Ronald M. Fussell (Altamonte Springs, Florida); Julie J. Anderson (Merritt Island, Florida) |
| ABSTRACT | A system for on-board anomaly resolution for a vehicle has a data repository. The data repository stores data related to different systems, subsystems, and components of the vehicle. The data stored is encoded in a tree-based structure. A query engine is coupled to the data repository. The query engine provides a user and automated interface and provides contextual query to the data repository. An inference engine is coupled to the query engine. The inference engine compares current anomaly data to contextual data stored in the data repository using inference rules. The inference engine generates a potential solution to the current anomaly by referencing the data stored in the data repository. |
| FILED | Tuesday, October 17, 2006 |
| APPL NO | 11/550231 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 07741136 | Fitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | John L. Fitz (Windsor Mill, Maryland); Daniel S. Hinkel (Sykesville, Maryland); Scott C. Horst (Sykesville, Maryland) |
| ABSTRACT | The present invention is a method of fabricating a waveguide using a sacrificial spacer layer. The first step in this process is to fabricate the underlying optical semiconductor structure. A trench is then etched in this structure resulting in an underlying L-shaped structure. A sacrificial spacer layer is deposited in the trench. The waveguide is created in the trench on the sacrificial spacer layer using a mask layer to angle the vertex of the L-shaped structure. User-defined portions of the sacrificial spacer layer are subsequently removed to create air gaps between the waveguide and the sidewalls of the trench in the optical semiconductor. |
| FILED | Wednesday, May 13, 2009 |
| APPL NO | 12/454493 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/31 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07743122 | Hsieh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director of the National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan M. Hsieh (Seattle, Washington); Thomas Lotze (College Park, Maryland) |
| ABSTRACT | A method of reliably communicating via a computer network by identifying hub nodes in the network, identifying leaf nodes in the network, communicating from hub nodes to corresponding leaf nodes, reporting from leaf nodes to corresponding hub nodes, communicating between hub nodes, re-designating a leaf node as a hub node if the leaf node identifies a region of the network not known by a hub node, re-designating a hub node as a leaf node if the hub node becomes redundant, re-designating a leaf node as a hub node if the leaf node loses connectivity to its hub node, and returning to the third step for additional processing. |
| FILED | Wednesday, November 07, 2007 |
| APPL NO | 11/998984 |
| ART UNIT | 2455 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07740826 | Khabashesku et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Valery N. Khabashesku (Houston, Texas); Haiqing Peng (Houston, Texas); John L. Margrave (Bellaire, Texas); Mary Lou Margrave, legal representative (Bellaire, Texas); Wilbur Edward Billups (Houston, Texas); Yunming Ying (Houston, Texas) |
| ABSTRACT | A method for functionalizing the wall of single-wall or multi-wall carbon nanotubes involves the use of acyl peroxides to generate carbon-centered free radicals. The method allows for the chemical attachment of a variety of functional groups to the wall or end cap of carbon nanotubes through covalent carbon bonds without destroying the wall or endcap structure of the nanotube. Carbon-centered radicals generated from acyl peroxides can have terminal functional groups that provide sites for further reaction with other compounds. Organic groups with terminal carboxylic acid functionality can be converted to an acyl chloride and further reacted with an amine to form an amide or with a diamine to form an amide with terminal amine. The reactive functional groups attached to the nanotubes provide improved solvent dispersibility and provide reaction sites for monomers for incorporation in polymer structures. The nanotubes can also be functionalized by generating free radicals from organic sulfoxides. |
| FILED | Tuesday, October 24, 2006 |
| APPL NO | 11/585368 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 07741611 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Yanfeng Du (Rexford, New York); Naresh Kesavan Rao (Clifton Park, New York); Brian David Yanoff (Niskayuna, New York); Wen Li (Clifton Park, New York) |
| ABSTRACT | A radiation detector includes at least one multiple channel pixelated detector driven via a plurality of pixelated anode electrodes and at least one planar cathode electrode. Each detector is configured to reduce the number of active pixelated anode electrodes until a rate of events detected via at least one corresponding planar cathode electrode exceeds a preset threshold above a background count rate within a predetermined time period. |
| FILED | Wednesday, July 23, 2008 |
| APPL NO | 12/220230 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07741113 | Strong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Loma Linda University (Loma Linda, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); Northwestern University (Evanston, Illinois); University of South Alabama (Mobile, Alabama) |
| INVENTOR(S) | Donna D. Strong (Loma Linda, California); Thomas A. Linkhart (Loma Linda, California); David A. Dean (Chicago, Illinois) |
| ABSTRACT | A plasmid, viral or linear DNA molecule containing a nucleic acid sequence derived from the promoter region of the hCol1α2 gene, which is selectively transported into the nuclei of cells in the osteoblast lineage. The sequence can be used independently as a nuclear entry sequence only, and/or as a nuclear entry sequence without regard to position, in a vector or linear DNA that directs gene expression and nuclear entry. The disclosure further includes a chimeric DNA sequence derived by the addition of osteoblast-specific enhancer sequences to the nuclear entry sequence/promoter sequence, to increase osteoblast-specific expression while retaining osteoblast-specific nuclear import. An enhancer sequence is derived from the promoter region of the human Core Binding Factor alpha 1 (Cbfa1/Runx2) gene. The Cbfa1/Runx2 promoter can be added to the sequence derived from, or alternatively, comprising the promoter region of the hCol1α2 gene. Also provided are methods of use of the novel sequences. |
| FILED | Monday, April 24, 2006 |
| APPL NO | 11/410579 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07740826 | Khabashesku et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Valery N. Khabashesku (Houston, Texas); Haiqing Peng (Houston, Texas); John L. Margrave (Bellaire, Texas); Mary Lou Margrave, legal representative (Bellaire, Texas); Wilbur Edward Billups (Houston, Texas); Yunming Ying (Houston, Texas) |
| ABSTRACT | A method for functionalizing the wall of single-wall or multi-wall carbon nanotubes involves the use of acyl peroxides to generate carbon-centered free radicals. The method allows for the chemical attachment of a variety of functional groups to the wall or end cap of carbon nanotubes through covalent carbon bonds without destroying the wall or endcap structure of the nanotube. Carbon-centered radicals generated from acyl peroxides can have terminal functional groups that provide sites for further reaction with other compounds. Organic groups with terminal carboxylic acid functionality can be converted to an acyl chloride and further reacted with an amine to form an amide or with a diamine to form an amide with terminal amine. The reactive functional groups attached to the nanotubes provide improved solvent dispersibility and provide reaction sites for monomers for incorporation in polymer structures. The nanotubes can also be functionalized by generating free radicals from organic sulfoxides. |
| FILED | Tuesday, October 24, 2006 |
| APPL NO | 11/585368 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07739829 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Zhangjing Chen (Blacksburg, Virginia); Marshall S. White (Blacksburg, Virginia); William H. Robinson (Christiansburg, Virginia) |
| ABSTRACT | Insect pests can be transported around the world in wooden shipping containers. To prevent the spread of wood-borne insect pests, it is necessary to kill insects within the wood. The wood is placed in a vacuum container having a flexible wall. The flexible wall presses against the wood and enables the wood to be heated by conduction. The wood and flexible wall can to be heated by contact with ambient or heated air, for example. Desiccant or dry air can be used to increase the rate of dehydration. Insects in the wood are typically killed after losing 25-50% of their body weight by dehydration. This technique will kill beetle larvae, nematodes and other invasive and destructive insects that live inside solid wood, and is particularly applicable for rendering wood acceptable for use in pallets and other containers shipped internationally. |
| FILED | Monday, July 11, 2005 |
| APPL NO | 11/574551 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Fishing, trapping, and vermin destroying 043/132.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07740303 | Wood |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Wood (Virginia Beach, Virginia) |
| ABSTRACT | A device for the reduction of aerodynamic drag and for improved performance and stability of ground vehicles by reducing the mass and velocity of the flow passing under a vehicle is described. The device is particularly suited for a tractor-trailer truck system that includes a motorized lead vehicle pulling one or more non-motorized vehicles. The device is designed to control the flow from entering the undercarriage region from the side of a trailer of a tractor-trailer truck system. |
| FILED | Monday, January 12, 2009 |
| APPL NO | 12/319726 |
| ART UNIT | 3612 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Land vehicles: Bodies and tops 296/180.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07741929 | Hash |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Harris Corporation (Melbourne, Florida) |
| INVENTOR(S) | Ronald J. Hash (Palm Bay, Florida) |
| ABSTRACT | A radio frequency (RF) directional coupler (100) can include a first transmission line element (102) having a first end and a second end, and a second transmission line element (104) having a first end and a second end. The first and second transmission line elements (102, 104) can be disposed in a first plane, where at least a portion of said first and said second transmission line elements (102, 104) are adjacent along a path. The RF coupler (100) can also include a first series of conductive coupling elements (116) disposed along said path in a second plane parallel to the first plane and separated from said first and said second transmission line elements (102, 104) by a first dielectric element (114). The first and second plane can be separated by a pre-determined distance (t2) to increase a capacitive coupling between the first and second transmission line elements (102, 104). |
| FILED | Monday, August 11, 2008 |
| APPL NO | 12/189240 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 22, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100622.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page