FedInvent™ Patents
Patent Details for Tuesday, June 29, 2010
This page was updated on Monday, March 27, 2023 at 01:51 AM GMT
Department of Health and Human Services (HHS)
| US 07744535 | Vanderby et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ray Vanderby (Madison, Wisconsin); Hirohito Kobayashi (Madison, Wisconsin) |
| ABSTRACT | An ultrasound machine processes ultrasonic data according to acoustoelastic properties of the materials to obtain strain information without specific assumptions with respect to the material properties of the measured material or a variety of different material properties normally not obtained by ultrasound machines. |
| FILED | Monday, October 16, 2006 |
| APPL NO | 11/549865 |
| ART UNIT | 3737 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Surgery 6/438 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744590 | Eells et al. |
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| ASSIGNEE(S) | Medical College of Wisconsin Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Janis T. Eells (Madison, Wisconsin); Margaret T. T. Wong-Riley (Brookfield, Wisconsin); Harry T. Whelan (Whitefish Bay, Wisconsin) |
| ABSTRACT | A method of treating visual system disease is disclosed. One embodiment comprises the steps of (a) exposing a component of a patient's visual system to light treatment, wherein the light treatment is characterized by wavelength of between 630-1000 nm and power intensity between 10-90 mW/cm2 for a time of 1-3 minutes, and (b) observing restoration of visual system function. |
| FILED | Thursday, March 27, 2008 |
| APPL NO | 12/056458 |
| ART UNIT | 3769 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Surgery 66/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744773 | Shih et al. |
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| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Hongyu Luo (Duncan, Oklahoma); Christian Martorano (Marlton, New Jersey); Wan Y. Shih (Bryn Mawr, Pennsylvania) |
| ABSTRACT | A method to produce low-temperature sinterable powders which are then subsequently used to fabricate freestanding piezoelectric films with very large electric-field-enhanced piezoelectric response is provided. The −d31 coefficient for PMN-PT layers can be as high as 2000 pm/V, larger than that of commercial single crystalline PMN-PT bulk materials, at 10 kV/cm (or 20 V over the 20-micron film thickness). In contrast to single crystals, the polycrystalline freestanding films are easy to fabricate and can be made into any size. The films are also easily miniaturized. The method can be applied to nearly any piezoelectric material. |
| FILED | Wednesday, March 29, 2006 |
| APPL NO | 11/392116 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions 252/62.9R0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744870 | Waldman |
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| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Scott A. Waldman (Ardmore, Pennsylvania) |
| ABSTRACT | Conjugated compounds which comprises an ST receptor binding moiety and a radiostable active moiety are disclosed. Pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent, and a conjugated compound which comprises an ST receptor binding moiety and a radiostable active moiety or an ST receptor binding moiety and a radioactive, active moiety are disclosed. Methods of treating an individual suspected of suffering from metastasized colorectal cancer comprising the steps of administering to said individual a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent, and a therapeutically effective amount of a conjugated compound which comprises an ST receptor binding moiety and a radiostable active moiety or an ST receptor binding moiety and a radiostable active moiety are disclosed. Methods of radioimaging metastasized colorectal cancer cells comprising the steps of first administering to an individual suspected of having metastasized colorectal cancer cells, a pharmaceutical composition that comprises a pharmaceutically acceptable carrier or diluent, and conjugated compound that comprises an ST receptor binding moiety and a radioactive active moiety wherein the conjugated compound is present in an amount effective for diagnostic use in humans suffering from colorectal cancer and then detecting the localization and accumulation of radioactivity in the individual's body are disclosed. |
| FILED | Tuesday, November 28, 2000 |
| APPL NO | 09/724983 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744879 | Shusta et al. |
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| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Xin X. Wang (Gaithersburg, Maryland); Yongku P. Cho (Madison, Wisconsin) |
| ABSTRACT | This invention provides antibodies that bind brain endothelial cell receptors resulting in endocytosis/transcytosis of the receptor and bound ligands. In some embodiments, the ligand comprises the antibody in combination with a pharmaceutically active compound and the antibody directs delivery of the compound across the blood brain barrier (BBB). The invention also provides methods of identifying endothelial cell specific antibodies by panning the library against cultured cell monolayers. The invention further allows for identifying endothelial cell receptors that bind the antibody thereby providing target receptors against which to isolate further cognate ligands and their associated transport systems and by which to identify transcytosis transporters targeted by the antibodies. |
| FILED | Thursday, June 07, 2007 |
| APPL NO | 11/759723 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/135.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744882 | Maihle et al. |
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| ASSIGNEE(S) | Tumor Biology Investment Group, Inc. (Lexington, Kentucky) |
| INVENTOR(S) | Nita J. Maihle (New Haven, Connecticut); Hakjoo Lee (Pittsford, New York) |
| ABSTRACT | Regulation of sErbB3 isoforms in methods of regulating heregulin activity or ErbB receptor activities is disclosed. Cancer therapeutics and methods of therapeutically treating cancer comprising sErbB3 are also disclosed. Detection of sErbB3 in biological samples for risk assessment and prevention, screening, diagnosis, prognosis, theragnosis, evaluation of responsiveness to treatment, and/or monitoring of disease progression, recurrence, or metastasis of a cancer is disclosed as well. In examples, sErbB3 nucleic acid sequences, polypeptides, molecular probes, and antibodies are useful agents for regulation, expression, detection, and cancer therapeutics related to sErbB3. |
| FILED | Monday, June 23, 2008 |
| APPL NO | 12/144375 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744894 | Liu et al. |
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| INVENTOR(S) | Yang Liu (Columbus, Ohio); Pan Zheng (Columbus, Ohio); Xuefeng Bai (Columbus, Ohio) |
| ABSTRACT | Methods for blocking autoreactive T cell-initiated destruction of tissues in a mammal are provided. In one embodiment, the methods involve administering an HAS/CD24 polypeptide or fragment thereof. In some embodiments, the polypeptide or fragment is glycosylated. |
| FILED | Friday, May 13, 2005 |
| APPL NO | 11/129083 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744898 | Chisari |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Francis V. Chisari (Del Mar, California) |
| ABSTRACT | Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. |
| FILED | Thursday, September 08, 2005 |
| APPL NO | 11/221470 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/189.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744899 | Whitley et al. |
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| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Richard J. Whitley (Birmingham, Alabama); Bernard Roizman (Chicago, Illinois) |
| ABSTRACT | Recombinant herpes simplex viruses comprising DNA encoding cytokines and methods for treating neoplastic diseases using the inventive recombinant viruses are disclosed. |
| FILED | Wednesday, October 11, 2006 |
| APPL NO | 11/546233 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744901 | Yang et al. |
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| ASSIGNEE(S) | MedImmune, LLC (Gaithersburg, Maryland); National Institute of Health (Rockville, Maryland) |
| INVENTOR(S) | Chin-Fen Yang (San Jose, California); George Kemble (Saratoga, California); Kanta Subbarao (Washington, District of Columbia); Brian Murphy (Bethesda, Maryland) |
| ABSTRACT | Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided. |
| FILED | Thursday, January 15, 2009 |
| APPL NO | 12/354085 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/206.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744902 | Krempl et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Christine D. Krempl (Wuerzburg, Germany); Peter L. Collins (Silver Spring, Maryland); Brian R. Murphy (Bethesda, Maryland); Ursula Buchholz (Silver Spring, Maryland); Stephen S. Whitehead (Montgomery Village, Maryland) |
| ABSTRACT | Recombinant respiratory syncytial virus (RSV) having the position of genes shifted within the genome or antigenome of the recombinant virus are infectious and attenuated in humans and other mammals. Gene shifted RSV are constructed by insertion, deletion or rearrangement of genes or genome segments within the recombinant genome or antigenome and are useful in vaccine formulations for eliciting an anti-RSV immune response. Also provided are isolated polynucleotide molecules and vectors incorporating a recombinant RSV genome or antigenome wherein a gene or gene segment is shifted to a more promoter-proximal or promoter-distal position within the genome or antigenome compared to a wild type position of the gene in the RSV gene map. Shifting the position of genes in this manner provides for a selected increase or decrease in expression of the gene, depending on the nature and degree of the positional shift. In one embodiment, RSV glycoproteins are upregulated by shifting one or more glycoprotein-encoding genes to a more promoter-proximal position. Genes of interest for manipulation to create gene position-shifted RSV include any of the NS1, NS2, N, P, M, SH, M2(ORF1), M2(ORF2), L, F or G genes or a genome segment that may be part of a gene or extragenic. A variety of additional mutations and nucleotide modifications are provided within the gene position-shifted RSV of the invention to yield desired phenotypic and structural effects. |
| FILED | Monday, January 10, 2005 |
| APPL NO | 11/033055 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/211.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744903 | Koelle et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | David M. Koelle (Seattle, Washington); Lawrence Corey (Seattle, Washington) |
| ABSTRACT | The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent epitopes confirmed to be recognized by T-cells derived from herpetic lesions or from uterine cervix. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection. |
| FILED | Thursday, February 10, 2005 |
| APPL NO | 11/055477 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/229.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745113 | Evans et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sylvia M. Evans (Del Mar, California); Ju Chen (San Diego, California); Chenleng Cai (San Diego, California); Alessandra Moretti (La Jolla, California); Kenneth R. Chien (La Jolla, California); Karl-Ludwig Laugwitz (La Jolla, California) |
| ABSTRACT | The present invention provides in vitro methods of expansion and propagation of undifferentiated progenitor cells and more specifically undifferentiated progenitor cells containing Islet1, a marker apparently unique to proliferating cardiac stem cells. Methods are described for isolation of stem cell populations as well as for provoking expansion and propagation of undifferentiated progenitor cells without differentiation, to provide cardiac repair or improve cardiac function, for example. |
| FILED | Monday, February 02, 2004 |
| APPL NO | 10/544053 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745123 | Hancock et al. |
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| ASSIGNEE(S) | GE Healthcare UK Limited (Cardiff, United Kingdom); Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Suzanne Hancock (Cardiff, United Kingdom); Simon Stubbs (Cardiff, United Kingdom); Nicholas Thomas (Cardiff, United Kingdom); Ellen Fanning (Nashville, Tennessee); Jinming Gu (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to non-destructive and dynamic means for determining the cell cycle position of living cells. The invention provides stable cell lines which can be used to determine the cell cycle position, together with methods for measuring the effect of a test agent on the cell cycle position. |
| FILED | Friday, July 22, 2005 |
| APPL NO | 11/572516 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745144 | Roberts et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | David D. Roberts (Bethesda, Maryland); Henry C. Krutzsch (Bethesda, Maryland) |
| ABSTRACT | The present invention relates to a peptide comprising the sequence R1—X1—X2—X3—X4—R2, wherein X1 is selected from the group consisting of N, Q, D and S; X2 is selected from the group consisting of V, I and L; X1 is selected from the group consisting of R and K; and X4 is selected from the group consisting of V, I, L and F; R1 is a hydrogen or a peptide of 1 to 6 amino acids, and acyl or an aryl group; and R2 is a peptide of 1 to 3 amino acids, a hydroxide or an amide. The invention also relates to partial or full retro-inverso peptides comprising the above sequences. The invention also relates to peptide-substrate combination comprising a substrate suitable for cell growth and the peptide of the invention, and to a vascular graft and an artificial blood vessel comprising the peptide-substrate combination. The invention also relates to a pharmaceutical composition and a peptide conjugate comprising the peptide of the invention. The invention also relates to a method of inhibiting adhesion of a cell expressing α3β1 integrin to an extracellular matrix, inhibiting α3β1-integrin-mediated cell motility, inhibiting α3β1-integrin mediated cell proliferation, promoting α3β1-integrin mediated cell proliferation and inhibiting angiogenesis utilizing the peptides of the invention. |
| FILED | Wednesday, August 23, 2006 |
| APPL NO | 11/466718 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745151 | He et al. |
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| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Zhigang He (Boston, Massachusetts); Kevin C. Wang (Boston, Massachusetts); Jieun A. Kim (Boston, Massachusetts) |
| ABSTRACT | Inhibitors of Nogo Receptor (NgR)-p75 binding are used to reduce NgR-p75 binding mediated axon growth inhibition. Mixtures of NgR and p75 are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to p75 and promoting axon regeneration. |
| FILED | Friday, August 02, 2002 |
| APPL NO | 10/211157 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745155 | Lin et al. |
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| ASSIGNEE(S) | Massachusetts General Hospital (Boston, Massachusetts) |
| INVENTOR(S) | Charles P. Lin (Arlington, Massachusetts); Xunbin Wei (Quincy, Massachusetts); Dorothy Sipkins (Evanston, Illinois) |
| ABSTRACT | The present invention provides methods and systems for performing in vivo flow cytometry. In one embodiments, selected circulating cells of interest of a subject are labeled with fluorescent probe molecules. The labeled cells are irradiated in-vivo so as to excite the fluorescent probes, and the radiation emitted by the excited probes is detected, preferably confocally. The detected radiation is then analyzed to derive desired information, such as relative cell count, of the cells of interest. In some embodiments, the circulating cells comprise apoptotic cells whose detection can allow, e.g., non-invasive monitoring of the efficacy of a cancer treatment, such as an anti-tumor or an anti-angiogenic therapy. |
| FILED | Wednesday, July 27, 2005 |
| APPL NO | 11/190729 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745163 | Blanchard |
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| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | John S. Blanchard (Pelham, New York) |
| ABSTRACT | The present invention is directed to a method of identifying an acetyltransferase substrate in a sample that includes the steps of: (a) contacting the sample with (i) a reagent comprising a thiol-containing compound, a halo-acetyl-CoA or a halo-acetyl-pantetheine, and (ii) an acetyltransferase, under conditions suitable for acetyltransferase enzyme activity, and (b) identifying a substrate that has formed a base-stable covalent bond to the reagent, wherein the reagent is labeled with a label and/or the acetyltransferase is labeled with an affinity tag, and the substrate is the acetyltransferase substrate. |
| FILED | Friday, October 01, 2004 |
| APPL NO | 10/574307 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745165 | Vogelstein et al. |
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| ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Saurabh Saha (New York, New York); Alberto Bardelli (Turin, Italy) |
| ABSTRACT | Among the genes identified, in a comparison of the global gene expression profile of metastatic colorectal cancer to that of primary cancers, benign colorectal tumors, and normal colorectal epithelium, the PRL-3 protein tyrosine phosphatase gene was of particular interest. It was expressed at high levels in each of 18 cancer metastases studied but at lower levels in non-metastatic tumors and normal colorectal epithelium. In three of twelve metastases examined, multiple copies of the PRL-3 gene were found within a small amplicon located at chromosome 8q24.3. These data suggest that the PRL-3 gene is important for colorectal cancer metastasis and provides a new therapeutic target for these intractable lesions. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/868658 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745166 | Lobel et al. |
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| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Newark, New Jersey) |
| INVENTOR(S) | Peter Lobel (Highland Park, New Jersey); David Sleat (Scotch Plains, New Jersey) |
| ABSTRACT | The gene associated and causative of classical late infantile neuronal ceroid lipofuscinosis (LINCL), CLN2, has been identified and characterized. The translation product of this gene is a novel protease and a deficiency in this activity results in LINCL. Identification of CLN2 will not only aid in the prevention of LINCL through genetic counseling but provides strategies and test systems for therapeutic intervention. In addition, further characterization of this previously unknown lysosomal enzyme may provide useful insights into other more common human neurodegenerative disorders. Finally, the utility of a general approach for determining the molecular bases for lysosomal disorders of unknown etiology has been demonstrated. |
| FILED | Thursday, July 17, 2008 |
| APPL NO | 12/175427 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745173 | Verdin et al. |
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| ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Eric M. Verdin (San Francisco, California); Wolfgang Fischle (Charlottesville, Virginia); Franck O. Dequiedt (San Francisco, California) |
| ABSTRACT | The present invention provides nucleic acid molecules that encode histone deacetylase, as well as recombinant vectors and host cells that include the subject nucleic acid molecules. Also provided are histone deacetylase polypeptide compositions. The histone deacteylase nucleic acid molecules are useful in a variety of diagnostic and therapeutic applications, which are also provided. |
| FILED | Friday, January 11, 2008 |
| APPL NO | 12/013277 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745185 | Thomae et al. |
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| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, New Mexico) |
| INVENTOR(S) | Bianca A. Thomae (Chicago, Illinois); Eric D. Wieben (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota) |
| ABSTRACT | Isolated sulfotransferase 1A3 nucleic acid molecules and polypeptides that include nucleotide sequence variants and amino acid sequence variants are described. Methods for determining predisposition to particular clinical conditions and methods for determining sulfonator status also are described. |
| FILED | Tuesday, May 27, 2008 |
| APPL NO | 12/127110 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745187 | Freimuth et al. |
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| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Robert R Freimuth (Rochester, Minnesota); Eric D Wieben (Rochester, Minnesota); Richard M Weinshilboum (Rochester, Minnesota) |
| ABSTRACT | Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to thyroid disease or cancer also are described. |
| FILED | Thursday, March 05, 2009 |
| APPL NO | 12/398700 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745188 | Woodgate et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Roger Woodgate (Rockville, Maryland); John P. McDonald (Germantown, Maryland); Wei Yang (Silver Spring, Maryland) |
| ABSTRACT | The present disclosure is related to thermostable Y-family polymerases, in particular several novel Y-family polymerases and chimeras made therefrom, as well as methods of identifying other Y-family polymerases, methods of generating other chimeric Y-family polymerases, methods of amplifying ancient or damaged DNA, and methods of incorporating fluorescent or modified nucleotides into a DNA molecule. |
| FILED | Friday, May 20, 2005 |
| APPL NO | 11/596783 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745200 | Cregg |
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| ASSIGNEE(S) | Research Corporation Technologies, Inc. (Tucson, Arizona) |
| INVENTOR(S) | James M. Cregg (Claremont, California) |
| ABSTRACT | The present invention provides formaldehyde dehydrogenase genes (FLD) from methylotrophic yeasts. The FLD structural genes confer resistance to formaldehyde and are therefore useful as a selectable marker in methylotrophic yeasts. The FLD promoter sequences are strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source). Induction under either methanol, methylamine or both provides levels of heterologous gene expression comparable to those obtained with the commonly used alcohol oxidase I gene promoter (PAOX1). The FLD promoter of Pichia pastoris (PFLD1) is an attractive alternative to PAOX1 for expression of foreign genes in P. pastoris, allowing regulation by carbon (methanol) or nitrogen (methylamine) source within the same expression strain. Yeast strains, expression cassettes, expression vectors, and host cells-comprising an FLD gene promoter and 3′ termination sequence are also provided. |
| FILED | Monday, June 04, 2007 |
| APPL NO | 11/810089 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/254.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745206 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Hongda Wang (Changchun, China PRC); Stuart Lindsay (Phoenix, Arizona) |
| ABSTRACT | An atomic force microscope and a method for detecting interactions between a probe and two or more sensed agents on a scanned surface and determining the relative location of two or more sensed agents is provided. The microscope has a scanning probe with a tip that is sensitive to two or more sensed agents on said scanned surface; two or more sensing agents tethered to the tip of the probe; and a device for recording the displacement of said probe tip as a function of time, topographic images, and the spatial location of interactions between said probe and the two or more sensed agents on said surface. |
| FILED | Tuesday, January 29, 2008 |
| APPL NO | 12/022072 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745207 | Jovanovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | IntegenX, Inc. (Pleasanton, California) |
| INVENTOR(S) | Stevan B. Jovanovich (Livermore, California); Iuliu I. Blaga (Fremont, California) |
| ABSTRACT | Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense. |
| FILED | Friday, February 02, 2007 |
| APPL NO | 11/670866 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745212 | Kawakami et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Yutaka Kawakami (Kanagawa, Japan); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the MART-1 melanoma antigen and a second melanoma antigen designated gp100. This invention further provides immunogenic peptides derived from the MART-1 melanoma antigen or gp100 antigen which have been modified to enhance their immunogenicity. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/932338 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745215 | Shirwan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Haval Shirwan (Louisville, Kentucky) |
| ABSTRACT | The present invention provides methods and compositions for expanding Treg cells ex vivo or in vivo using one or more conjugates comprising a costimulatory moiety that stimulates at least one of three signals involved in Treg cell development and/or using dendritic cells pulsed with antigens and modified to display TGF-β, or hematopoetic stem cells or bone marrow cells modified to display TGF-β. The methods and compositions are useful, for example, in the treatment and prevention of autoimmune disease, including Type 1 diabetes and in preventing foreign graft rejection, as well as to establish mixed chimerism, induce tolerance to autoantigens, alloantigens or xenoantigens, beta cell regeneration, prevention of foreign graft rejection, and treatment of a genetically inherited hematopoietic disorder. |
| FILED | Thursday, December 07, 2006 |
| APPL NO | 11/635087 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745220 | Abbott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Brian H. Clare (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides devices and methods for detection of analytes based on measuring the anchoring strength of liquid crystals having distorted geometries. Methods for detecting an analyte in a sample include the steps of: (a) capturing an analyte on a substrate surface wherein the substrate surface defines an easy axis when in contact with a liquid crystal. Substrate surface and liquid crystal are brought into contact and an analyte-dependent departure in the orientation of the liquid crystal from the easy axis of the substrate surface is measured. This departure indicates the presence of the analyte in the sample. |
| FILED | Tuesday, October 03, 2006 |
| APPL NO | 11/542432 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745230 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Creighton University (Omaha, Nebraska) |
| INVENTOR(S) | Zhao Yi Wang (Bellevue, Nebraska) |
| ABSTRACT | The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-α36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO:1, or an immunogenic fragment thereof, and methods for making and using such antibodies. |
| FILED | Thursday, March 10, 2005 |
| APPL NO | 10/591199 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/548 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745377 | Hahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Klaus M. Hahn (Chapel Hill, North Carolina); Alexei Toutchkine (Chapel Hill, North Carolina); Rajeev Muthyala (Flushing, New York); Vadim Kraynov (San Diego, California); Steven J. Bark (San Diego, California); Dennis R. Burton (La Jolla, California); Chester Chamberlain (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides peptide synthons having protected functional groups for attachment of desired moieties (e.g. functional molecules or probes). Also provided are peptide conjugates prepared from such synthons, and synthon and conjugate preparation methods including procedures for identifying the optimum probe attachment site. Biosensors are provided having environmentally sensitive dyes that can locate specific biomolecules within living cells and detect chemical and physiological changes in those biomolecules as the living cell is moving, metabolizing and reacting to its environment. Methods are included for detecting GTP activation of a Rho GTPase protein using polypeptide biosensors. When the biosensor binds GTP-activated Rho GTPase protein, the environmentally sensitive dye emits a signal of a different lifetime, intensity or wavelength than when not bound. New fluorophores whose fluorescence responds to environmental changes are also provided that have improved detection and attachment properties, and that can be used in living cells, or in vitro. |
| FILED | Thursday, May 05, 2005 |
| APPL NO | 11/122795 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745388 | Mochly-Rosen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | National Institute of Health (NIH) (Bethesda, Maryland); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); The United States of America as represented by NIH Division of Extramural Inventions and Technology Resources (DEITR) (Washington, District of Columbia) |
| INVENTOR(S) | Daria Mochly-Rosen (Menlo Park, California); Leon E. Chen (Cupertino, California) |
| ABSTRACT | Peptides able to inhibit or activate the translocation or function of δPKC are identified. Administration of the peptides for protection or enhancement of cell damage due to ischemia is described. Therapeutic methods to reduce damage to cells or to enhance damage to cells due to ischemia are also described, as well as methods for screening test compounds for δPKC-selective agonists and antagonists. |
| FILED | Wednesday, May 12, 2004 |
| APPL NO | 10/843731 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745389 | Hageman |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Gregory S. Hageman (Coralville, Iowa) |
| ABSTRACT | The invention relates to Factor H gene polymorphisms and haplotypes associated with an elevated or a reduced risk of AMD. The invention provides methods and reagents for diagnosis and treatment of AMD. |
| FILED | Tuesday, February 14, 2006 |
| APPL NO | 11/354559 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745390 | Clayberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Carol Clayberger (Stanford, California); Alan M. Krensky (Stanford, California) |
| ABSTRACT | Artificial antimicrobial peptides are obtained by alterations in alpha helical portions of a known antimicrobial protein, granulysin. The peptides obtained have significantly improved antimicrobial activity and lack the ability to lyse mammalian cells, which may be toxic to a host. The peptides may be designed according to certain guidelines, and may further be modified by the addition of altered residues and alterations in normal peptide secondary and tertiary structure, including modifications in quaternary (multimeric) structure. |
| FILED | Monday, May 22, 2006 |
| APPL NO | 11/438563 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745398 | Maihle et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Tumor Biology Investment Group, Inc. (Lexington, Kentucky) |
| INVENTOR(S) | Nita J. Maihle (New Haven, Connecticut); Hakjoo Lee (Pittsford, New York) |
| ABSTRACT | Regulation of sErbB3 isoforms in methods of regulating heregulin activity or ErbB receptor activities is disclosed. Cancer therapeutics and methods of therapeutically treating cancer comprising sErbB3 are also disclosed. Detection of sErbB3 in biological samples for risk assessment and prevention, screening, diagnosis, prognosis, theragnosis, evaluation of responsiveness to treatment, and/or monitoring of disease progression, recurrence, or metastasis of a cancer is disclosed as well. In examples, sErbB3 nucleic acid sequences, polypeptides, molecular probes, and antibodies are useful agents for regulation, expression, detection, and cancer therapeutics related to sErbB3. |
| FILED | Monday, June 23, 2008 |
| APPL NO | 12/144344 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745401 | Pereira et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | H. Anne Pereira (Edmond, Oklahoma); Paul Fidel (Mandeville, Louisiana) |
| ABSTRACT | A method of treating fungal infections by treatment with CAP37 peptides and derivatives thereof, including peptide analogs having serine or threonine substitutions at least one of the two cysteine residues therein. Other substitutions of the amino acid residues of the peptide are also contemplated. |
| FILED | Monday, July 31, 2006 |
| APPL NO | 11/497178 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745402 | Omary et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lundbeck Inc. (Deerfield, Illinois) |
| INVENTOR(S) | Bishr Omary (Mountain View, California); Stephen Collins (Lake Forest, Illinois) |
| ABSTRACT | The present invention provides a method of treating pancreatitis comprising administering to a human in need thereof an effective amount of hemin. The administration of hemin is preferably parenteral. In another aspect, the present invention provides a method of pancreatitis prophylaxis comprising administering to a human in need thereof an effective amount of hemin. In a still further aspect, the present invention contemplates a method of inducing an HO gene comprising administering to a human in need thereof an HO-inducing effective amount of hemin. Preferably, the HO gene is the HO-1 gene. In a still further aspect, the present invention contemplates a method of inducing an HO gene in leukocytes for recruitment to the pancreas to treat pancreatitis comprising administering to a human in need thereof an HO-inducing effective amount of hemin. In another embodiment, the present invention contemplates a method of inducing an HO gene in leukocytes for recruitment to the pancreas for prophylaxis of pancreatitis comprising administering to a human in need thereof an HO-inducing effective amount of hemin. In a yet further aspect, the present invention provides a method of ex vivo treatment of pancreatitis comprising providing peripheral blood leukocytes, followed by contact with hemin to form induced peripheral blood leukocytes then infusing the induced peripheral blood leukocytes into a human in need thereof. |
| FILED | Monday, October 02, 2006 |
| APPL NO | 11/542522 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745406 | Econs et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Advanced Research and Technology Institute (Indianapolis, Indiana); Ludwig-Maximilians-Universitat Munchen Abteilung Medizinische Genetik (Munich, Germany) |
| INVENTOR(S) | Michael Econs (Indianapolis, Indiana); Ken White (Carmel, Indiana); Tim Matthias Strom (Munich, Germany); Thomas Meitinger (Munich, Germany) |
| ABSTRACT | The present invention relates to a kit for diagnosing a disorder comprising a reagent that detects FGF23 polypeptides and mutant FGF23 polypeptides. |
| FILED | Wednesday, November 07, 2007 |
| APPL NO | 11/983137 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745412 | Mochly-Rosen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Daria Mochly-Rosen (Menlo Park, California) |
| ABSTRACT | A method of changing or otherwise converting the biological activity of a PKC peptide agonist to a peptide antagonist is described. The method involves substituting one or more amino acid residues so as to effect a change in charge in the peptide and/or to otherwise make the sequence similar to a sequence derived from the PKC binding site on the RACK protein for the respective PKC enzyme. Methods of inhibiting the activity of a PKC enzyme, and various peptide antagonists of εPKC are also disclosed. |
| FILED | Monday, September 15, 2008 |
| APPL NO | 12/283921 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745416 | Dillman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wolfgang H. Dillman (Solana Beach, California); Frank Giordano (Del Mar, California); Ruben Mestril (San Diego, California) |
| ABSTRACT | A method for regulating in vivo calcium transport in cardiac muscle of animals suffering from congestive heart failure is disclosed. According to the method, calcium ATPase activity (which decreases as congestive heart failure develops) and cardiac muscle contractility augmented by delivering a gene which operatively encodes the enzyme into the heart. Delivery systems, including but not limited to using adeno-associated viral vectors are provided. Methods for monitoring the expression and effect of the gene product on cardiac performance are also provided. |
| FILED | Monday, January 13, 2003 |
| APPL NO | 10/342120 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745421 | Bochner et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bruce S. Bochner (Lutherville, Maryland); Ronald L. Schnaar (Columbia, Maryland) |
| ABSTRACT | The invention provides therapeutic methods and compositions for the prevention and treatment of Siglec-8 associated diseases and disorders such as asthma and allergic reactions. In particular, the invention provides methods and compositions for the prevention and treatment of diseases and disorders associated with Siglec-8 expressing cells in humans, as well as other animals, through the administration of one or more novel, carbohydrate-based compounds. |
| FILED | Tuesday, May 24, 2005 |
| APPL NO | 11/597336 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745422 | Sanders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John M. Sanders (Collegeville, Pennsylvania); Yongcheng Song (Pearland, Texas); Julian M. W. Chan (Boston, Massachusetts); Eric Oldfield (Champaign, Illinois); Yonghui Zhang (Urbana, Illinois) |
| ABSTRACT | Bisphosphonate compounds and related methods of making and using are disclosed, including pyridinium-1-yl, quinolinium-1-yl, and related compounds. The activity of compounds is disclosed in the context of functional assays such as Leishmania major farnesyl diphosphate synthase (FPPS) inhibition, Dictyostelium discoideum growth inhibition, human gamma delta T cell activation, and bone resorption. The applicability of bisphosphonate compounds in the context of parasitic infections, for example against trypanosomes, is disclosed. Further potential applications of the invention are disclosed regarding the treatment of one or more conditions such as bone resorption disorders, cancer, bone pain, infectious diseases, and in immunotherapy. |
| FILED | Tuesday, April 15, 2008 |
| APPL NO | 12/103551 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745456 | Boykin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Duke University (Durham, North Carolina); Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | David W. Boykin (Atlanta, Georgia); Richard R. Tidwell (Pittsboro, North Carolina); W. David Wilson (Atlanta, Georgia); John R. Perfect (Durham, North Carolina); Chad F. Stephens (Villa Rica, Georgia) |
| ABSTRACT | The present invention relates to novel 2,5-bis{[alkyl (or aryl) imino] aminophenyl}furans and thiophenes of the general formula in which R1, R2, R3 and R4 are each independently selected from the group consisting of H, alkyl, alkoxy, halide, and alkylhalide groups; R5 is H, alkyl or aryl; R6 is H, alkyl, aryl, or NR7R8, in which R7 and R8 are each independently selected from the group consisting of H, alkyl and aryl; and X is O, S or NR9, in which R9 is H or alkyl, and to the use of such compounds. |
| FILED | Monday, July 09, 2007 |
| APPL NO | 11/825786 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745485 | Durden |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Donald L. Durden (Indianapolis, Indiana) |
| ABSTRACT | Methods are provided for the identification, biochemical characterization and therapeutic use of agents which impact PTEN, p53, PI-kinase and AKT mediated cellular signaling. |
| FILED | Tuesday, December 23, 2008 |
| APPL NO | 12/342848 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745489 | Dennis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Edward Dennis (La Jolla, California); Tony Yaksh (San Diego, California); Karin Killermann Lucas (San Diego, California); Camilla Svensson (San Diego, California); David A. Six (Durham, North Carolina); George Kokotos (Athens, Greece); Violetta Constantinou-Kokotou (Athens, Greece) |
| ABSTRACT | Specific, highly potent 2-oxo-amide based inhibitors of phospholipase A2 (PLA2) activity are provided. A role for PLA2 activity in spinally mediated inflammatory processes is established, and a method for treating hyperalgesia and other inflammatory conditions associated with PLA2 activity is provided. |
| FILED | Friday, March 07, 2003 |
| APPL NO | 10/506059 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/553 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745494 | Perez-Soler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Roman Perez-Soler (New York, New York); Yi-He Ling (Briarwood, New York) |
| ABSTRACT | The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin. |
| FILED | Wednesday, April 12, 2006 |
| APPL NO | 11/886803 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/682 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745569 | Martin |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Paul Taylor Martin (Bexley, Ohio) |
| ABSTRACT | Phage peptide display technology was used to identify peptides that bind specifically to the amyloid form of the Aβ1-40 peptide. Peptides with similar structural features and bind to the amyloid form of Aβ1-40 but not to monomeric Aβ1-40, are provided. Such peptides are useful as carrier molecules to deliver therapeutic and diagnostic reagents to amyloid plaques. |
| FILED | Wednesday, April 07, 2004 |
| APPL NO | 10/551619 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745574 | Satterthwait et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Arnold Satterthwait (San Diego, California); Xiao-kun Zhang (San Diego, California); Xiuwen Zhu (San Diego, California); Siva Kolluri (San Diego, California) |
| ABSTRACT | Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and related Bcl-2 family members are identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing or preventing apoptosis are described, together with methods for identifying molecules that induce or prevent apoptosis through interaction with Bcl-2-family members. Methods for treatment of proliferative diseases and neurodegenerative diseases using the modulators of Bcl-2 and related family members are also disclosed. |
| FILED | Thursday, May 11, 2006 |
| APPL NO | 11/433783 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745578 | Poznansky et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mark C. Poznansky (Charlestown, Massachusetts); Dahlia Doughty (Charlestown, Massachusetts) |
| ABSTRACT | This invention relates to compositions and methods that modulate the movement of cells with migratory capacity. More specifically, the invention relates to compositions and methods for promoting migratory movement, fugetaxis, of cells from a specific site in a subject. The foregoing are useful, inter alia, in the treatment of conditions characterized by a need to promote migratory cell movement away from specific sites in a subject. Specific sites include sites of inflammation, infection, an autoimmune reaction, a tumor and a transplanted organ or tissue. |
| FILED | Wednesday, July 07, 2004 |
| APPL NO | 10/563726 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745581 | Glimcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Laurie H. Glimcher (West Newton, Massachusetts); Susanne J. Szabo (Somerville, Massachusetts) |
| ABSTRACT | Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet. |
| FILED | Thursday, February 21, 2008 |
| APPL NO | 12/070856 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745584 | Tully et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sarah E. Tully (Olmstead, Ohio); Linda Hsieh-Wilson (San Marino, California) |
| ABSTRACT | The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to chondroitin sulfate, particularly CS-A, CS-C and CS-E tetrasaccharides. The present invention also relates to methods of making anti-CS antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment. |
| FILED | Tuesday, May 22, 2007 |
| APPL NO | 11/751863 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745589 | Spielmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Hans Peter Spielmann (Lexington, Kentucky); Douglas A. Andres (Lexington, Kentucky) |
| ABSTRACT | Unnatural substrates of prenylation enzymens and antibodies that recognize unique moieties of prenylated proteins, which unique moieties are transferred from the unnatural substrates are used for detecting and isolating prenylated proteins, and for screening for inhibitors of prenylation enzymes. |
| FILED | Friday, July 21, 2006 |
| APPL NO | 11/459299 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/389.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745600 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York) |
| INVENTOR(S) | Sho-Ya Wang (Voorheesville, New York) |
| ABSTRACT | A method or screen for assessing the potential of a compound to treat a pathological condition, such as arrhythmia, which is manifested by an increased late sodium current in a heart is disclosed. The method employs a mutant sodium channel protein having an amino acid sequence in which one or more amino acids among the ten amino acids occurring at the carboxy end of the S6 segments of D1, D2, D3 or D4 domains of mammalian Nav1 differs from the amino acid in wild-type Nav1 by substitution with tryptophan, phenylalanine, tyrosine or cysteine. Cells transfected with a nucleic acid that encodes a mutant mammalian Nav1 protein, as well as isolated nucleic acid comprising a nucleotide sequence that codes for a mutant mammalian Nav1 protein are disclosed. |
| FILED | Monday, August 21, 2006 |
| APPL NO | 11/507232 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745601 | Zuker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Charles S. Zuker (San Diego, California); Jon Elliot Adler (Sherwood, Oregon); Mark Hoon (Kensington, Maryland); Nick Ryba (Bethesda, Maryland); Ken Mueller (San Diego, California) |
| ABSTRACT | The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors. |
| FILED | Friday, October 19, 2007 |
| APPL NO | 11/975655 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745604 | Low et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Malcolm J. Low (Lake Oswego, Oregon); Marcelo Rubinstein (Buenos Aires, Argentina); Flavio Silva Junqueira de Souza (Buenos Aires, Argentina) |
| ABSTRACT | The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein. |
| FILED | Thursday, August 10, 2006 |
| APPL NO | 11/503426 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745614 | Kool et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Eric Todd Kool (Stanford, California); Hiroshi Abe (Mountain View, California) |
| ABSTRACT | A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer. |
| FILED | Thursday, September 01, 2005 |
| APPL NO | 11/218961 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/26.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745618 | Kiper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Dilek Dogutan Kiper (Raleigh, North Carolina); Marcin Ptaszek (Raleigh, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | A method of making a compound of Formula I: is carried out by condensing a pair of compounds of Formula II (which pair may be the same or different), or by condensing a compound of Formula III with a compound Formula IV, to produce a compound of Formula I. The condensing step may be carried out with a metal salt under basic conditions. |
| FILED | Monday, February 25, 2008 |
| APPL NO | 12/036395 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745691 | Farese, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Robert V. Farese, Jr. (Kentfield, California); Hubert C. Chen (Newbury Parl, California); Steven J. Smith (San Francisco, California); Sylvaine Cases (Belmont, California); Sandra K. Erickson (San Francisco, California) |
| ABSTRACT | Methods and compositions for modulating carbohydrate metabolism in a host are provided. In the subject methods, diacylglycerol acyltransferase (DGAT) activity (specifically DGAT1 activity) is modulated, e.g., reduced or enhanced, to achieve a desired insulin and/or leptin sensitivity, thereby modulating carbohydrate metabolism, e.g., increasing or decreasing blood glucose levels, glucose uptake into cells and assimilation into glycogen. Also provided are pharmaceutical compositions for practicing the subject methods. The subject methods and compositions find use in a variety of applications, including the treatment of hosts suffering conditions associated with abnormal carbohydrate metabolism, such as obesity or diabetes. |
| FILED | Tuesday, December 12, 2006 |
| APPL NO | 11/609810 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745973 | Bayram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Baris Bayram (Stanford, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | A reduced crosstalk capacitive micromachined ultrasonic transducer (CMUT) array is provided. The CMUT array has at least two CMUT array elements deposited on a substrate, at least one CMUT cell in the array element, a separation region between adjacent CMUT array elements, and a membrane formed in the separation region. The membrane reduces crosstalk between adjacent array elements, where the crosstalk is a dispersive guided mode of an ultrasonic signal from the CMUT propagating in a fluid-solid interface of the CMUT array. Each cell has an insulation layer deposited to the substrate. A cell membrane layer is deposited to the insulation layer, where the cell membrane layer has a vacuum gap therein. The cells further have an electrode layer deposited to a portion of the membrane layer, and a passivation layer deposited to the electrode layer, the cell membrane layer and to the insulation layer. |
| FILED | Monday, April 23, 2007 |
| APPL NO | 11/789210 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747315 | Villard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Joseph W. Villard (St. Louis, Missouri); Marc D. Feldman (San Antonio, Texas); Thomas E. Milner (Austin, Texas); JeeHyun Kim (Austin, Texas); Gregory L. Freeman (San Antonio, Texas) |
| ABSTRACT | Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention has particular advantages in imaging within the cardiovascular system and highly vascularized or oxygen-dependent tissues. |
| FILED | Wednesday, January 15, 2003 |
| APPL NO | 10/500577 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747395 | Scheinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | David A. Scheinberg (New York, New York); Sindy Noemi Escobar-Alvarez (New York, New York); Yehuda Goldgur (Fair Lawn, New Jersey); Yueming Li (New York, New York) |
| ABSTRACT | The present invention provides the three-dimensional structure of human mitochondrial Homo sapiens peptide deformylase (HsPDF) protein, and HsPDF complexed to a binding compound, such as a PDF inhibitor. This crystallographic information will aid in the identification and development of novel binding compounds of HsPDF and other PDF family members which have anti-bacterial, anti-viral, anti-parasitical, anti-inflammatory, and/or anti-cancer activity. |
| FILED | Friday, April 13, 2007 |
| APPL NO | 11/787237 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07743433 | Grove et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Corey M. Grove (Red Lion, Pennsylvania); Stephen E. Chase (Jarrettsville, Maryland); Mary P. McCully (Fallston, Maryland); Janelle E. Keberle (Bel Air, Maryland); Leroy H. Stitz (Lutherville, Maryland); Adam D. Seiple (Rosedale, Maryland) |
| ABSTRACT | A neck dam collar is formed of a substantially vapor-proof material. Resiliently compressible portions of the collar either act as a cushion, a spacer, or both between a neck dam and the wearer's neck. In one embodiment, the collar is a discrete, cylindrical tube of flexible, elastic material. In another embodiment, a protective garment includes the neck dam collar. |
| FILED | Tuesday, April 11, 2006 |
| APPL NO | 11/401682 |
| ART UNIT | 3765 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Apparel 02/465 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07743619 | Tilton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Isothermal Research Systems, Inc. (Liberty Lake, Washington) |
| INVENTOR(S) | Charles L. Tilton (Colton, Washington); Philip W. Appel (Spokane, Washington) |
| ABSTRACT | A heat exchanger system for efficiently thermally managing coolant within a multiple-phase thermal management system. The heat exchanger system includes a thermal management unit, a release valve within the thermal management unit to release vaporized coolant, and a heat exchanger fluidly connected to the release valve and to the thermal management unit to return liquid coolant to the thermal management unit. |
| FILED | Friday, January 06, 2006 |
| APPL NO | 11/327181 |
| ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Refrigeration 062/259.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07743647 | Israel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Joshua D. Israel (Baltimore, Maryland); Corey L. Piepenburg (Nottingham, Maryland); Malcolm D. Goodman (Forest Hill, Maryland) |
| ABSTRACT | An orifice test calibration device tests the functionality of protective mask testers. The orifice test calibration device has a semi-rigid tubular channel with one end for sealing the flow outlet port of the protective mask tester and a second end for sealing the vacuum inlet port of the protective mask tester. The device also includes a sealable opening within the tubular channel and an insertable orifice plug having a set diameter for insertion into the sealable opening in order to calibrate the protective mask tester. |
| FILED | Thursday, August 21, 2008 |
| APPL NO | 12/195814 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07743967 | Frankel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Ohio State University (Columbus, Ohio) |
| INVENTOR(S) | Gerald S. Frankel (Columbus, Ohio); John C. Lippold (Hilliard, Ohio) |
| ABSTRACT | A chromium-free welding consumable and a method of welding stainless steel to reduce the presence of chromium emissions. The consumable is made from an alloy that reduces the emission of chromium during a welding process, and include predominantly nickel, with between approximately five and twenty five percent by weight copper, up to approximately five percent by weight of palladium, up to approximately ten percent by weight of molybdenum and up to five percent non-copper alloying ingredients. Welding consumables made from the alloy are particularly well-suited for welding austenitic stainless steels, such as type 304 stainless steel. The method involves using chromium-free weld filler material with a stainless steel base material. |
| FILED | Monday, February 11, 2008 |
| APPL NO | 12/028891 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Metal fusion bonding 228/262.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744017 | Cooke |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies Holding S.arl (Troy, Michigan) |
| INVENTOR(S) | Michael P. Cooke (Gillingham, United Kingdom) |
| ABSTRACT | An injection nozzle for an internal combustion engine comprising a nozzle body defining a seating surface and having at least one first nozzle outlet and a valve member received within the nozzle body and engageable with an external seating defined by the seating surface so as to control fuel injection through the at least one first nozzle outlet. The valve member is provided with a bore having an internal bore surface and an insert is received within the bore. The insert includes a part-spherical head which spans an internal diameter of the bore so as to maintain contact with an internal surface of the bore as the valve member moves, in use, so as to guide movement of the valve member. The part-spherical head also includes a surface which defines an internal seating for the valve member. |
| FILED | Tuesday, July 11, 2006 |
| APPL NO | 11/484466 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/102.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744310 | Alpern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as reprensented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert L. Alpern (Westfield, New Jersey); Diane S. Rahoy (Roselle Park, New Jersey); David N. Rackmales (New York, New York) |
| ABSTRACT | A self-adjusting barrier incorporates a series of float units restrained between a primary wall, such as a bulkhead, and a secondary wall, such as sheetpile. The secondary wall may be braced to the primary wall. The float units slidably interconnect along adjacent edges to self-adjust along a perimeter, such as a marina or waterfront lot, based on the height of water within the chamber (stilling basin) provided between the two walls. Mechanisms for deterring vandalism and providing increased environmental integrity are also provided for select embodiments. Methods of employing the barrier are also disclosed. |
| FILED | Wednesday, January 02, 2008 |
| APPL NO | 12/006757 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hydraulic and earth engineering 45/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744590 | Eells et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Medical College of Wisconsin Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Janis T. Eells (Madison, Wisconsin); Margaret T. T. Wong-Riley (Brookfield, Wisconsin); Harry T. Whelan (Whitefish Bay, Wisconsin) |
| ABSTRACT | A method of treating visual system disease is disclosed. One embodiment comprises the steps of (a) exposing a component of a patient's visual system to light treatment, wherein the light treatment is characterized by wavelength of between 630-1000 nm and power intensity between 10-90 mW/cm2 for a time of 1-3 minutes, and (b) observing restoration of visual system function. |
| FILED | Thursday, March 27, 2008 |
| APPL NO | 12/056458 |
| ART UNIT | 3769 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Surgery 66/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744673 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Xingmao Jiang (Albuquerque, New Mexico); Charles Jeffrey Brinker (Albuquerque, New Mexico) |
| ABSTRACT | In accordance with invention, there are methods for fabricating hollow spheres and nanofoams. The method for making hollow spheres can include providing a homogeneous precursor solution including a first solvent and one or more anhydrous precursor species and forming aerosol droplets having a first size distribution using the homogeneous precursor solution in an anhydrous carrier gas. The method can also include transporting the aerosol droplets through an aerosol reactor including a reactant to form a plurality of hollow spheres, wherein each of the plurality of hollow spheres can be formed by one or more chemical reactions occurring at a surface of the aerosol droplet. The method can further include controlling size and thickness of the hollow spheres by one or more of the precursor solution concentration, aerosol droplet size, temperature, residence time of the aerosol droplets in the aerosol reactor, and the reactant distribution in the aerosol reactor. |
| FILED | Monday, October 22, 2007 |
| APPL NO | 11/876338 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/348 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744690 | Durst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Bartley P. Durst (Clinton, Mississippi); Billy D. Neeley (Vicksburg, Mississippi); Edward F. O'Neil (Vicksburg, Mississippi); Toney K. Cummins (Vicksburg, Mississippi) |
| ABSTRACT | Concrete with improved strength and toughness. A uniform mix of first constituents comprises: cement of Blaine fineness of 280-360 m2/kg; sand at a mass ratio of 0.75-1.25 of the cement; silica fume at a mass ratio of 0.15-0.4 of the cement; silica flour at a mass ratio of 0.15-0.3 of the cement; and microinclusions at a mass ratio up to 0.35 of the cement. This is then mixed with a blend of second constituents comprising a specified amount of an HRWRA and an amount of water at a mass ratio of 0.2-0.35 of the cement. This is mixed sufficiently to form a uniform cement-based paste to which an amount of macrofibers at a mass ratio of up to 0.35 of the cement is added to yield a uniform product. Nanoinclusions may be added to improve crack resistance and increase density. |
| FILED | Tuesday, March 28, 2006 |
| APPL NO | 11/390084 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions: Coating or plastic 16/644 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744812 | Witherspoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Utron Inc. (Manassas, Virginia) |
| INVENTOR(S) | F. Douglas Witherspoon (Fairfax Station, Virginia); Dennis W. Massey (Markham, Virginia); T. Arul Mozhi (Springfield, Virginia); David L. Kruczynski (Amissville, Virginia); John M. Ryan (Fairfax, Virginia) |
| ABSTRACT | A gas operated part forming die apparatus has compact high tonnage presses which are operated by high pressure gas generated within chambers and controlled to operate high pressure pistons and dies for compressing particulate material into dense formed parts. Combustion chambers are filled with pressurized mixtures of combustible gases and diluents. Elongated chambers have insulating walls and spaced electrodes. Some contain liquid or particulate ablatable materials or ablatable liners. Others extend fuzes between the electrodes and are filled with pressurized gases. Gas is removed from the particulate material. Die cavities may be precompressed during filing of chambers with pressurized gas. Igniting the combustible gases or creating arcs between the electrodes produces rapidly expanding high pressure resultant gases for driving pistons and movable dies and rapidly compressing die cavities. Pressures in the chambers are contained, or pistons are restrained until releasing and driving the pistons. Large area pistons drive smaller movable dies. |
| FILED | Friday, July 23, 2004 |
| APPL NO | 10/896947 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Powder metallurgy processes 419/66 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744843 | Gogotsi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yury Gogotsi (Ivyland, Pennsylvania) |
| ABSTRACT | Methods for synthesizing single-wall carbon nanotubes by extracting metals from a carbide by halogen treatment at a temperature ranging between 700 to 1700° C. at ambient or low pressure are provided. |
| FILED | Wednesday, June 15, 2005 |
| APPL NO | 11/571104 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744957 | Forrest et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Max Shtein (Ann Arbor, Michigan) |
| ABSTRACT | A method of depositing organic material is provided. A carrier gas carrying an organic material is ejected from a nozzle at a flow velocity that is at least 10% of the thermal velocity of the carrier gas, such that the organic material is deposited onto a substrate. In some embodiments, the dynamic pressure in a region between the nozzle and the substrate surrounding the carrier gas is at least 1 Torr, and more preferably 10 Torr, during the ejection. In some embodiments, a guard flow is provided around the carrier gas. In some embodiments, the background pressure is at least about 10e-3 Torr, more preferably about 0.1 Torr, more preferably about 1 Torr, more preferably about 10 Torr, more preferably about 100 Torr, and most preferably about 760 Torr. A device is also provided. The device includes a nozzle, which further includes a nozzle tube having a first exhaust aperture and a first gas inlet; and a jacket surrounding the nozzle tube, the jacket having a second exhaust aperture and a second gas inlet. The second exhaust aperture completely surrounds the first tube aperture. A carrier gas source and an organic source vessel may be connected to the first gas inlet. A guard flow gas source may be connected to the second gas inlet. The device may include an array of such nozzles. |
| FILED | Thursday, October 23, 2003 |
| APPL NO | 10/690704 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/249.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744963 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanson, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Seunghun Hong (Chicago, Illinois); Vinayak P. Dravid (Glenview, Illinois) |
| ABSTRACT | In one aspect, a method of nanolithography is provided, the method comprising providing a substrate; providing a scanning probe microscope tip; coating the tip with a deposition compound; and subjecting said coated tip to a driving force to deliver said deposition compound to said substrate so as to produce a desired pattern. Another aspect of the invention provides a tip for use in nanolithography having an internal cavity and an aperture restricting movement of a deposition compound from the tip to the substrate. The rate and extent of movement of the deposition compound through the aperture is controlled by a driving force. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/933181 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/457 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745023 | Flickinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Michael C. Flickinger (Roseville, Minnesota); Caroline S. Harwood (Seattle, Washington); Federico Rey (Coralville, Iowa) |
| ABSTRACT | The present invention provides composite biological devices that include biological material as an integral component thereof. The devices can be used for producing hydrogen gas, for example. |
| FILED | Monday, August 09, 2004 |
| APPL NO | 10/915934 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745100 | Kohl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Paul A. Kohl (Atlanta, Georgia); SueAnn Bidstrup Allen (Atlanta, Georgia); Xiaoqun Wu (Wilmington, Delaware); Clifford Lee Henderson (Douglasville, Georgia) |
| ABSTRACT | Polymers, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary polymer, among others, includes, a photodefinable polymer having a sacrificial polymer and a photoinitiator. |
| FILED | Monday, June 12, 2006 |
| APPL NO | 11/451144 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745102 | Fedynyshyn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Theodore H. Fedynyshyn (Sudbury, Massachusetts); Indira Pottebaum (Boston, Massachusetts) |
| ABSTRACT | Compositions for use as immersion fluids are described. In general, the immersion fluids can be utilized to perform lithography at short wavelengths (e.g., in a range from about 120 nm to about 260 nm). Some embodiments can be used in a range of actinic radiation between about 140 nm and about 160 nm (e.g., about 157 nm). Immersion fluids can exhibit any number of advantageous features including a relatively high index of refraction (e.g., greater than about 1, or greater than about 1.3, or about greater than about 1.4) and/or a relatively low absorbance (e.g., lower than about 2 μm−1, or lower than about 1 μm−1, or lower than about 0.5 μm−1). Some immersion fluids can include silicon-containing compounds and/or germanium containing compounds. Such compounds can include at least one Ge—O bond or at least one Si—O bond. Such compounds can also include one or more fluorinated moieties. |
| FILED | Tuesday, May 29, 2007 |
| APPL NO | 11/754615 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/322 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745136 | Dorsey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Russell M. Dorsey (Joppa, Maryland) |
| ABSTRACT | A method for detecting ribosome inactivating protein (RIP) activity in a sample is provided that involves contacting a sample that contains an RIP with an inventive substrate that is depurinated to form product. The product is hybridized to a template and cleaved by an apurinic/apyrimidinic endonuclease such that releasing the blocked 3′ end only in a sample that contains RIP activity. The 5′ end of the product serves as a primer for extension by a polymerase reaction. The newly synthesized strand complementary to the template is detected by RT-PCR processes. A kit is provided suitable for field or laboratory use. |
| FILED | Friday, January 30, 2009 |
| APPL NO | 12/362599 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745148 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Functional Genetics, Inc. (Gaithersburg, Maryland) |
| INVENTOR(S) | Roxanne Duan (Bethesda, Maryland); Michael Goldblatt (McLean, Virginia) |
| ABSTRACT | The invention reflects enhanced antibody expression of an antibody of interest by cell lines transformed by random homozygous gene perturbation methods to either increase or decrease the expression pattern of a gene of the cell line other than the antibody of interest. The transformed cell line exhibits specific productivity rates, SPR, for the RHGP transformed cell liens of 1.5 or more, as compared with the antibody expressing cell line parents prior to transformation by RHGP. A knock out or anti-sense construct may be devised to reduce expression of the target gene, a promoter may be inserter to enhance expression of the target gene. The antibodies expressed by the transformed cell lines exhibit the binding properties of their parent cell lines prior to transformation with RHGP, and increase Total Volumetric Production of said antibody by said cells in a given volume. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 11/928393 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745207 | Jovanovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | IntegenX, Inc. (Pleasanton, California) |
| INVENTOR(S) | Stevan B. Jovanovich (Livermore, California); Iuliu I. Blaga (Fremont, California) |
| ABSTRACT | Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense. |
| FILED | Friday, February 02, 2007 |
| APPL NO | 11/670866 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745248 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Kwan Kyu Park (Stanford, California); Mario Kupnik (Mountain View, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | The current invention provides methods of fabricating a capacitive micromachined ultrasonic transducer (CMUT) that includes oxidizing a substrate to form an oxide layer on a surface of the substrate having an oxidation-enabling material, depositing and patterning an oxidation-blocking layer to form a post region and a cavity region on the substrate surface and remove the oxidation-blocking layer and oxide layer at the post region. The invention further includes thermally oxidizing the substrate to grow one or more oxide posts from the post region, where the post defines the vertical critical dimension of the device, and bonding a membrane layer onto the post to form a membrane of the device. A maximum allowed second oxidation thickness t2 can be determined, that is partially based on a desired step height and a device size, and a first oxidation thickness t1 can be determined that is partially based on the determined thickness t2. |
| FILED | Tuesday, October 14, 2008 |
| APPL NO | 12/288009 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745272 | Van de Walle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Christian G. Van de Walle (Santa Barbara, California); Kiesel Peter (Palo Alto, California); Oliver Schmidt (Palo Alto, California) |
| ABSTRACT | A semiconductor device has a heterostructure including a first layer of semiconductor oxide material. A second layer of semiconductor oxide material is formed on the first layer of semiconductor oxide material such that a two dimensional electron gas builds up at an interface between the first and second materials. A passivation layer on the outer surface stabilizes the structure. The device also has a source contact and a drain contact. |
| FILED | Wednesday, August 27, 2008 |
| APPL NO | 12/199378 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/167 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745330 | Santiago et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francisco Santiago (Fredericksburg, Virginia); Victor H. Gehman, Jr. (Dahlgren, Virginia); Karen J. Long (Upper Marlboro, Maryland); Kevin A. Boulais (Waldorf, Maryland) |
| ABSTRACT | Carbon nanotube apparatus, and methods of carbon nanotube modification, include carbon nanotubes having locally modified properties with the positioning of the modifications being controlled. More specifically, the positioning of nanotubes on a substrate with a deposited substance, and partially vaporizing part of the deposited substance etches the nanotubes. The modifications of the carbon nanotubes determine the electrical properties of the apparatus and applications such as a transistor or Shockley diode. Other applications of the above mentioned apparatus include a nanolaboratory that assists in study of merged quantum states between nanosystems and a macroscopic host system. |
| FILED | Tuesday, July 31, 2007 |
| APPL NO | 11/890102 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/660 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745540 | Devadoss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brewer Science Inc. (Rolla, Missouri) |
| INVENTOR(S) | Chelladurai Devadoss (Hillsboro, Oregon); Mandar Bhave (Austin, Texas); Runhui Huang (Rolla, Michigan) |
| ABSTRACT | New anti-reflective or fill compositions having improved flow properties are provided. The compositions comprise a dendritic polymer dispersed or dissolved in a solvent system, and preferably a light attenuating compound, a crosslinking agent, and a catalyst. The inventive compositions can be used to protect contact or via holes from degradation during subsequent etching in the dual damascene process. The inventive compositions can also be applied to substrates (e.g., silicon wafers) to form anti-reflective coating layers having high etch rates which minimize or prevent reflection during subsequent photoresist exposure and developing. |
| FILED | Friday, September 07, 2007 |
| APPL NO | 11/852137 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 525/326.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745574 | Satterthwait et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Arnold Satterthwait (San Diego, California); Xiao-kun Zhang (San Diego, California); Xiuwen Zhu (San Diego, California); Siva Kolluri (San Diego, California) |
| ABSTRACT | Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and related Bcl-2 family members are identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing or preventing apoptosis are described, together with methods for identifying molecules that induce or prevent apoptosis through interaction with Bcl-2-family members. Methods for treatment of proliferative diseases and neurodegenerative diseases using the modulators of Bcl-2 and related family members are also disclosed. |
| FILED | Thursday, May 11, 2006 |
| APPL NO | 11/433783 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745614 | Kool et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Eric Todd Kool (Stanford, California); Hiroshi Abe (Mountain View, California) |
| ABSTRACT | A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer. |
| FILED | Thursday, September 01, 2005 |
| APPL NO | 11/218961 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/26.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745633 | Irvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David J. Irvin (Ridgecrest, California); Mark H. Mason (Inyokern, California) |
| ABSTRACT | A linear isocyanate polymer produced by utilizing an effective amount of tetrazole diol or tetrazole polyol, reacting with an effective amount isocyanate resin, and cooling to room temperature producing a linear polyisocyanate polymer. |
| FILED | Wednesday, December 10, 2008 |
| APPL NO | 12/332221 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745708 | Stupp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Jeffrey D. Hartgerink (Pearland, Texas); Elia Beniash (Auburndale, Massachusetts) |
| ABSTRACT | Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. |
| FILED | Friday, September 28, 2007 |
| APPL NO | 11/863975 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Nanotechnology 977/705 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745800 | McGinnis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wayne C. McGinnis (San Diego, California) |
| ABSTRACT | A directional neutron detecting apparatus includes first and second neutron detectors. Each neutron detector includes a thin planar sheet of neutron-reactive material; a first ohmic electrode operably coupled to one side of the planar sheet of neutron-reactive material; a second ohmic electrode operably coupled to a second side of the planar sheet of neutron-reactive material; a voltage source operably coupled to the first and second ohmic electrodes; and an electrical current detector operably coupled in series between the first ohmic electrode and the voltage source. The first and second neutron detectors are arranged so that their planar neutron-reactive sheets are substantially parallel, opposing and are spaced from each other. Multiple directional neutron detecting apparatuses may be arranged mutually orthogonally to thereby provide omni-directional neutron detection. |
| FILED | Thursday, March 01, 2007 |
| APPL NO | 11/713835 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/390.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745816 | Mohseni |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Hooman Mohseni (Wilmette, Illinois) |
| ABSTRACT | A semiconductor photodetector for photon detection without the use of avalanche multiplication, and capable of operating at low bias voltage and without excess noise. In one embodiment, the photodetector comprises a plurality of InP/AlInGaAs/AlGaAsSb layers, capable of spatially separating the electron and the hole of an photo-generated electron-hole pair in one layer, transporting one of the electron and the hole of the photo-generated electron-hole pair into another layer, focalizing it into a desired volume and trapping it therein, the desired volume having a dimension in a scale of nanometers to reduce its capacitance and increase the change of potential for a trapped carrier, and a nano-injector, capable of injecting carriers into the plurality of InP/AlInGaAs/AlGaAsSb layers, where the carrier transit time in the nano-injector is much shorter than the carrier recombination time therein, thereby causing a very large carrier recycling effect. |
| FILED | Wednesday, September 27, 2006 |
| APPL NO | 11/528089 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745973 | Bayram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Baris Bayram (Stanford, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | A reduced crosstalk capacitive micromachined ultrasonic transducer (CMUT) array is provided. The CMUT array has at least two CMUT array elements deposited on a substrate, at least one CMUT cell in the array element, a separation region between adjacent CMUT array elements, and a membrane formed in the separation region. The membrane reduces crosstalk between adjacent array elements, where the crosstalk is a dispersive guided mode of an ultrasonic signal from the CMUT propagating in a fluid-solid interface of the CMUT array. Each cell has an insulation layer deposited to the substrate. A cell membrane layer is deposited to the insulation layer, where the cell membrane layer has a vacuum gap therein. The cells further have an electrode layer deposited to a portion of the membrane layer, and a passivation layer deposited to the electrode layer, the cell membrane layer and to the insulation layer. |
| FILED | Monday, April 23, 2007 |
| APPL NO | 11/789210 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746084 | Belkhayat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Newport News Shipbuilding and Dry Dock Company (Newport News, Virginia); The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Mohamed Belkhayat (Alexandria, Virginia); Jing Huang (Rolla, Missouri); Keith Corzine (Rolla, Missouri) |
| ABSTRACT | An unbalanced line-to-line current is injected at an injected frequency in a three-phase ac circuit. A first set of voltages and currents are obtained. A first set of transformed voltages and transformed currents are produced. The circuit is injected with a second unbalanced line-to-line current at a frequency linearly independent of the injected frequency. A second set of voltages and current are obtained. A second set of transformed voltages and transformed currents are produced The impedance of a source portion and a load portion of the circuit are calculated using the first and second set of transformed voltages, and the first and second set of transformed currents. |
| FILED | Friday, October 05, 2007 |
| APPL NO | 11/867965 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Measuring and testing 324/649 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746264 | Kirtchik |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Hyman Kirtchik (Cincinnati, Ohio) |
| ABSTRACT | An infrared camouflage coating system for application to the strategic surfaces of jet engine components comprised of a metal alloy substrate having an oxidized surface and a ferrous sulfide containing silicate glass bonded thereto. |
| FILED | Tuesday, July 11, 1978 |
| APPL NO | 05/924404 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746267 | Raney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Russell K. Raney (Annapolis, Maryland) |
| ABSTRACT | A synthetic aperture radar hybrid-polarity method and architecture comprising transmitting circular polarization (by driving the orthogonal linear feeds simultaneously by two identical waveforms, 90° out of phase), and receiving horizontal (H) and vertical (V) linear polarizations, coherently. Once calibrated, the H and V single-look complex amplitude data are sufficient to form all four Stokes parameters, which fully characterize the observed backscattered field. |
| FILED | Wednesday, May 07, 2008 |
| APPL NO | 12/116357 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.F00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746451 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Louisiana Tech University Research Foundation, A Division of Louisiana Tech University Foundation (Ruston, Louisiana) |
| INVENTOR(S) | Chester Wilson (Ruston, Louisiana); John W. Sweeney (Ruston, Louisiana); Kalyani Peri (Birmingham, Alabama); Rajesh Yalavarthy (Sunnyvale, California) |
| ABSTRACT | On-chip microplasma discharge devices capable of producing light, including ultraviolet light, capable of detecting atomic and molecular gas, and capable of detecting atomic and molecular contaminants in water samples. The on-chip microplasma discharge devices utilize nanoparticles or magnets to tune or confine microplasma discharges generated by electrodes delivering a voltage to the device. Selective control of the gaseous pressure at a value between atmospheric pressure and a vacuum pressure allows for further refinement of gas or contaminant detection, or for further tuning of the wavelength of the light to be produced. |
| FILED | Thursday, January 18, 2007 |
| APPL NO | 11/624494 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/72 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746466 | Godin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jessica Godin (San Diego, California); Yu-Hwa Lo (San Diego, California) |
| ABSTRACT | A flow cytometry system and related method, among other things, are disclosed. In at least one embodiment, the system includes first, second, and intermediate slab formations, the last of which has formed therewithin a microfluidic channel, a lens structure arranged proximate the microfluidic channel, and a light conveying structure arranged proximate to the lens structure. The lens structure is configured to direct a portion of light to proceed between the channel and the conveying structure. The intermediate slab formation is sandwiched between the other two slab formations. In at least another embodiment, the system includes a microfluidic prism arranged proximate to the second end of a light conveying structure. Light emanating from a microfluidic channel is provided to the conveying structure at the first end, conveyed to the second end, and provided to the prism, which outputs a plurality of portions of the light at different frequencies in different directions. |
| FILED | Wednesday, May 14, 2008 |
| APPL NO | 12/152665 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/246 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746686 | Katti |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Romney R. Katti (Shorewood, Minnesota) |
| ABSTRACT | A magnetic memory and a method of operating the memory are described. The memory includes memory cells that may each include a magnetoresistive bit. The memory cells may each be coupled to a current driver. Each current driver may be inhibited so that it does not output a current. Inhibiting the output current prevents the memory from being written. By inhibiting some current drivers and not inhibiting other current drivers, the memory may be partitioned into read only and random access portions. |
| FILED | Friday, April 21, 2006 |
| APPL NO | 11/409371 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746978 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
| INVENTOR(S) | Chieh C. Cheng (Redlands, California); David A. Lesyna (Redlands, California); Michael F. Moyers (Colton, California) |
| ABSTRACT | A patient positioning system for use with a radiation therapy system that monitors the location of fixed and movable components and pre-plans movement of the movable components so as to inhibit movement if a collision would be indicated. The positioning system can also coordinate movement of multiple movable components for reduced overall latency in registering a patient. The positioning system includes external measurement devices which measure the location and orientation of objects, including components of the radiation therapy system, in space and can also monitor for intrusion into the active area of the therapy system by personnel or foreign objects to improve operational safety of the radiation therapy system. |
| FILED | Monday, October 08, 2007 |
| APPL NO | 11/868918 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07743602 | Kalyanaraman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | ExxonMobil Research And Engineering Co. (Annandale, New Jersey); Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Mohan Kalyanaraman (Media, Pennsylvania); Paul W. Park (Peoria, Illinois); Christie S. Ragle (Havana, Illinois) |
| ABSTRACT | A method and apparatus for catalytically processing a gas stream passing therethrough to reduce the presence of NOx therein, wherein the apparatus includes a first catalyst composed of a silver-containing alumina that is adapted for catalytically processing the gas stream at a first temperature range, a second catalyst composed of a copper-containing zeolite located downstream from the first catalyst, wherein the second catalyst is adapted for catalytically processing the gas stream at a lower second temperature range relative to the first temperature range, a hydrocarbon compound for injection into the gas stream upstream of the first catalyst to provide a reductant, and a reformer for reforming a portion of the hydrocarbon compound into H2 and/or oxygenated hydrocarbon for injection into the gas stream upstream of the first catalyst. The second catalyst is adapted to facilitate the reaction of reducing NOx into N2, whereby the intermediates are produced via the first catalyst reacting with NOx and hydrocarbons. |
| FILED | Friday, September 01, 2006 |
| APPL NO | 11/514544 |
| ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Power plants 060/286 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07743648 | Berman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Gennady P. Berman (Los Alamos, New Mexico); Boris M. Chernobrod (Los Alamos, New Mexico) |
| ABSTRACT | The invention relates to scanning magnetic microscope which has a photoluminescent nanoprobe implanted in the tip apex of an atomic force microscope (AFM), a scanning tunneling microscope (STM) or a near-field scanning optical microscope (NSOM) and exhibits optically detected magnetic resonance (ODMR) in the vicinity of unpaired electron spins or nuclear magnetic moments in the sample material. The described spin microscope has demonstrated nanoscale lateral resolution and single spin sensitivity for the AFM and STM embodiments. |
| FILED | Tuesday, August 28, 2007 |
| APPL NO | 11/845982 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07743830 | Hermes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Chevron U.S.A. Inc. (San Ramon, California); Los Alamos National Security (Los Alamos, New Mexico) |
| INVENTOR(S) | Robert E. Hermes (Los Alamos, New Mexico); Manuel E. Gonzalez (Kingwood, Texas); Brian C. Llewellyn (Kingwood, Texas); James B. Bloys (Katy, Texas) |
| ABSTRACT | A process is described for replacing at least a portion of the liquid within the annular volume of a casing system within a wellbore with a second liquid. The second liquid is preselected to provide a measure of control of the pressure within the annular volume as the fluid within the volume is being heated. |
| FILED | Friday, October 10, 2008 |
| APPL NO | 12/249852 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744450 | Hoskinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Reed L. Hoskinson (Rigby, Idaho); Kevin L. Kenney (Idaho Falls, Idaho); Christopher T. Wright (Idaho Falls, Idaho); John R. Hess (Idaho Falls, Idaho) |
| ABSTRACT | A particulate residue separator and a method for separating a particulate residue stream may include a plenum borne by a harvesting device, and have a first, intake end and a second, exhaust end; first and second particulate residue air streams which are formed by the harvesting device and which travel, at least in part, along the plenum and in a direction of the second, exhaust end; and a baffle assembly which is located in partially occluding relation relative to the plenum, and which substantially separates the first and second particulate residue air streams. |
| FILED | Thursday, September 28, 2006 |
| APPL NO | 11/536076 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Crop threshing or separating 460/84 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744604 | Maitland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Duncan Maitland (Pleasant Hill, California); William J. Benett (Livermore, California); Jane P. Bearinger (Livermore, California); Thomas S. Wilson (San Leandro, California); Ward Small, IV (Livermore, California); Daniel L. Schumann (Concord, California); Wayne A. Jensen (Livermore, California); Jason M. Ortega (Pacifica, California); John E. Marion, III (Livermore, California); Jeffrey M. Loge (Stockton, California) |
| ABSTRACT | A system for removing matter from a conduit. The system includes the steps of passing a transport vehicle and a shape memory polymer material through the conduit, transmitting energy to the shape memory polymer material for moving the shape memory polymer material from a first shape to a second and different shape, and withdrawing the transport vehicle and the shape memory polymer material through the conduit carrying the matter. |
| FILED | Thursday, June 30, 2005 |
| APPL NO | 11/172668 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 66/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744733 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Proton Energy Systems, Inc. (Wallingford, Connecticut) |
| INVENTOR(S) | Amjad Khan (Newington, Connecticut); Ken Wayne Dreier (Madison, Connecticut); Lawrence Clinton Moulthrop (Windsor, Connecticut); Erik James White (Storrs, Connecticut) |
| ABSTRACT | A system to vent a moist gas stream is disclosed. The system includes an enclosure and an electrochemical cell disposed within the enclosure, the electrochemical cell productive of the moist gas stream. A first vent is in fluid communication with the electrochemical cell for venting the moist gas stream to an exterior of the enclosure, and a second vent is in fluid communication with an interior of the enclosure and in thermal communication with the first vent for discharging heated air to the exterior of the enclosure. At least a portion of the discharging heated air is for preventing freezing of the moist gas stream within the first vent. |
| FILED | Monday, March 05, 2007 |
| APPL NO | 11/681956 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/278 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744734 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Shelly X. Li (Idaho Falls, Idaho) |
| ABSTRACT | A high current density cathode for electrorefining in a molten electrolyte for the continuous production and collection of loose dendritic or powdery deposits. The high current density cathode eliminates the requirement for mechanical scraping and electrochemical stripping of the deposits from the cathode in an anode/cathode module. The high current density cathode comprises a perforated electrical insulated material coating such that the current density is up to 3 A/cm2. |
| FILED | Friday, August 24, 2007 |
| APPL NO | 11/844829 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744737 | James et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Conrad D. James (Albuquerque, New Mexico); Anil Kumar (Framingham, Massachusetts); Boris Khusid (New Providence, New Jersey); Andreas Acrivos (Stanford, California) |
| ABSTRACT | A microfluidic device comprising independently addressable arrays of interdigitated electrodes can be used to assembly and transport large-scale microparticle structures. The device and method uses collective phenomena in a negatively polarized suspension exposed to a high-gradient strong ac electric field to assemble the particles into predetermined locations and then transport them collectively to a work area for final assembly by sequentially energizing the electrode arrays. |
| FILED | Monday, February 11, 2008 |
| APPL NO | 12/028907 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/547 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744751 | Herling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Darrell R. Herling (Richland, Washington); Chris L. Aardahl (Richland, Washington); Robert T. Rozmiarek (Middleton, Wisconsin); Kenneth G. Rappe (Richland, Washington); Yong Wang (Richland, Washington); Jamelyn D. Holladay (Kennewick, Washington) |
| ABSTRACT | The present invention provides a process for producing reagents for a chemical reaction by introducing a fuel containing hydrocarbons into a flash distillation process wherein the fuel is separated into a first component having a lower average molecular weight and a second component having a higher average molecular weight. The first component is then reformed to produce synthesis gas wherein the synthesis gas is reacted catalytically to produce the desire reagent. |
| FILED | Monday, September 15, 2008 |
| APPL NO | 12/210741 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Mineral oils: Processes and products 28/361 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744813 | Brady et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Michael P. Brady (Oak Ridge, Tennessee); Bruce A. Pint (Knoxville, Tennessee); Chain-Tsuan Liu (Oak Ridge, Tennessee); Philip J. Maziasz (Oak Ridge, Tennessee); Yukinori Yamamoto (Oak Ridge, Tennessee); Zhao P. Lu (Oak Ridge, Tennessee) |
| ABSTRACT | An austenitic stainless steel displaying high temperature oxidation and creep resistance has a composition that includes in weight percent 15 to 21 Ni, 10 to 15 Cr, 2 to 3.5 Al, 0.1 to 1 Nb, and 0.05 to 0.15 C, and that is free of or has very low levels of N, Ti and V. The alloy forms an external continuous alumina protective scale to provide a high oxidation resistance at temperatures of 700 to 800° C. and forms NbC nanocarbides and a stable essentially single phase fcc austenitic matrix microstructure to give high strength and high creep resistance at these temperatures. |
| FILED | Thursday, January 04, 2007 |
| APPL NO | 11/619944 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Alloys or metallic compositions 420/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744830 | Morse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jeffrey D. Morse (Martinez, California); David A. Sopchak (Livermore, California); Ravindra S. Upadhye (Pleasanton, California); John G. Reynolds (San Ramon, California); Joseph H. Satcher (Patterson, California); Alex E. Gash (Brentwood, California) |
| ABSTRACT | A microreactor comprising a silicon wafer, a multiplicity of microchannels in the silicon wafer, and a catalyst coating the microchannels. In one embodiment the catalyst coating the microchannels comprises a nanostructured material. In another embodiment the catalyst coating the microchannels comprises an aerogel. In another embodiment the catalyst coating the microchannels comprises a solgel. In another embodiment the catalyst coating the microchannels comprises carbon nanotubes. |
| FILED | Thursday, April 28, 2005 |
| APPL NO | 11/119047 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/211 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744840 | Sobolevskiy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | Anatoly Sobolevskiy (Orlando, Florida); Joseph A. Rossin (Columbus, Ohio) |
| ABSTRACT | A selective catalytic reduction (SCR) process with a palladium catalyst for reducing NOx in a gas, using hydrogen as a reducing agent is provided. The process comprises contacting the gas stream with a catalyst system, the catalyst system comprising (ZrO2)SO4, palladium, and a pre-sulfated zirconia binder. The inclusion of a pre-sulfated zirconia binder substantially increases the durability of a Pd-based SCR catalyst system. A system for implementing the disclosed process is further provided. |
| FILED | Wednesday, May 27, 2009 |
| APPL NO | 12/472633 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744842 | Farha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Omar K. Farha (Evanston, Illinois); Joseph T. Hupp (Northfield, Illinois); Youn-Sang Bae (Evanston, Illinois); Randall Q. Snurr (Evanston, Illinois); Alexander M. Spokoyny (Evanston, Illinois); Chad A. Mirkin (Wilmette, Illinois) |
| ABSTRACT | A method of separating a mixture of carbon dioxide and a hydrocarbon gas using a metal-organic framework (MOF) material having a three-dimensional carborane ligand structure. |
| FILED | Monday, December 29, 2008 |
| APPL NO | 12/317775 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744899 | Whitley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Richard J. Whitley (Birmingham, Alabama); Bernard Roizman (Chicago, Illinois) |
| ABSTRACT | Recombinant herpes simplex viruses comprising DNA encoding cytokines and methods for treating neoplastic diseases using the inventive recombinant viruses are disclosed. |
| FILED | Wednesday, October 11, 2006 |
| APPL NO | 11/546233 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744963 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanson, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Seunghun Hong (Chicago, Illinois); Vinayak P. Dravid (Glenview, Illinois) |
| ABSTRACT | In one aspect, a method of nanolithography is provided, the method comprising providing a substrate; providing a scanning probe microscope tip; coating the tip with a deposition compound; and subjecting said coated tip to a driving force to deliver said deposition compound to said substrate so as to produce a desired pattern. Another aspect of the invention provides a tip for use in nanolithography having an internal cavity and an aperture restricting movement of a deposition compound from the tip to the substrate. The rate and extent of movement of the deposition compound through the aperture is controlled by a driving force. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/933181 |
| ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating processes 427/457 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745023 | Flickinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Michael C. Flickinger (Roseville, Minnesota); Caroline S. Harwood (Seattle, Washington); Federico Rey (Coralville, Iowa) |
| ABSTRACT | The present invention provides composite biological devices that include biological material as an integral component thereof. The devices can be used for producing hydrogen gas, for example. |
| FILED | Monday, August 09, 2004 |
| APPL NO | 10/915934 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745227 | Haas |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jeffrey S. Haas (San Ramon, California) |
| ABSTRACT | A system for analysis of explosives. Samples are spotted on a thin layer chromatography plate. Multi-component explosives standards are spotted on the thin layer chromatography plate. The thin layer chromatography plate is dipped in a solvent mixture and chromatography is allowed to proceed. The thin layer chromatography plate is dipped in reagent 1. The thin layer chromatography plate is heated. The thin layer chromatography plate is dipped in reagent 2. |
| FILED | Wednesday, August 11, 2004 |
| APPL NO | 10/915973 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/162 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745315 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | George T. Wang (Albuquerque, New Mexico); Qiming Li (Albuquerque, New Mexico); J. Randall Creighton (Albuquerque, New Mexico) |
| ABSTRACT | A method for forming vertically oriented, crystallographically aligned nanowires (nanocolumns) using monolayer or submonolayer quantities of metal atoms to form uniformly sized metal islands that serve as catalysts for MOCVD growth of Group III nitride nanowires. |
| FILED | Wednesday, October 03, 2007 |
| APPL NO | 11/866684 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/503 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745570 | Tomich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | John Tomich (Manhattan, Kansas); Takeo Iwamoto (Manhattan, Kansas); Xinchun Shen (Chapel Hill, North Carolina); Xiuzhi Susan Sun (Manhattan, Kansas) |
| ABSTRACT | A novel peptide adhesive motif is described that requires no receptor or cross-links to achieve maximal adhesive strength. Several peptides with different degrees of adhesive strength have been designed and synthesized using solid phase chemistries. All peptides contain a common hydrophobic core sequence flanked by positively or negatively charged amino acids sequences. |
| FILED | Friday, December 16, 2005 |
| APPL NO | 11/793187 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745679 | Wagh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | CH2M Hill, Inc. (Englewood, Colorado) |
| INVENTOR(S) | Arun Wagh (Naperville, Illinois); Martin D. Maloney (Evergreen, Colorado) |
| ABSTRACT | A method of stabilizing a waste in a chemically bonded phosphate ceramic (CBPC). The method consists of preparing a slurry including the waste, water, an oxide binder, and a phosphate binder. The slurry is then allowed to cure to a solid, hydrated CBPC matrix. Next, bound water within the solid, hydrated CBPC matrix is removed. Typically, the bound water is removed by applying heat to the cured CBPC matrix. Preferably, the quantity of heat applied to the cured CBPC matrix is sufficient to drive off water bound within the hydrated CBPC matrix, but not to volatalize other non-water components of the matrix, such as metals and radioactive components. Typically, a temperature range of between 100° C.-200° C. will be sufficient. In another embodiment of the invention wherein the waste and water have been mixed prior to the preparation of the slurry, a select amount of water may be evaporated from the waste and water mixture prior to preparation of the slurry. Another aspect of the invention is a direct anyhydrous CBPC fabrication method wherein water is removed from the slurry by heating and mixing the slurry while allowing the slurry to cure. Additional aspects of the invention are ceramic matrix waste forms prepared by the methods disclosed above. |
| FILED | Thursday, February 26, 2004 |
| APPL NO | 10/547445 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Hazardous or toxic waste destruction or containment 588/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745696 | Melis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anastasios Melis (El Cerrito, California); Mautusi Mitra (El Cerrito, California) |
| ABSTRACT | The invention provides method and compositions to minimize the chlorophyll antenna size of photosynthesis by decreasing TLA1 gene expression, thereby improving solar conversion efficiencies and photosynthetic productivity in plants, e.g., green microalgae, under bright sunlight conditions. |
| FILED | Monday, June 12, 2006 |
| APPL NO | 11/423620 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745708 | Stupp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Jeffrey D. Hartgerink (Pearland, Texas); Elia Beniash (Auburndale, Massachusetts) |
| ABSTRACT | Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. |
| FILED | Friday, September 28, 2007 |
| APPL NO | 11/863975 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Nanotechnology 977/705 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745765 | Kisner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Roger A. Kisner (Knoxville, Tennessee); John B. Wilgen (Oak Ridge, Tennessee); Gerard M. Ludtka (Oak Ridge, Tennessee); Roger A. Jaramillo (Knoxville, Tennessee); Gail Mackiewicz-Ludtka (Oak Ridge, Tennessee) |
| ABSTRACT | An apparatus and method for altering characteristics, such as can include structural, magnetic, electrical, optical or acoustical characteristics, of an electrically-conductive workpiece utilizes a magnetic field within which the workpiece is positionable and schemes for thermally treating the workpiece by heating or cooling techniques in conjunction with the generated magnetic field so that the characteristics of the workpiece are effected by both the generated magnetic field and the thermal treatment of the workpiece. |
| FILED | Monday, July 03, 2006 |
| APPL NO | 11/480683 |
| ART UNIT | 3742 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Electric heating 219/635 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745856 | Noy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Aleksandr Noy (Belmont, California); Olgica Bakajin (San Leandro, California); Sonia Létant (Livermore, California); Michael Stadermann (Dublin, California); Alexander B. Artyukhin (Menlo Park, California) |
| ABSTRACT | A sensor apparatus comprising a nanotube or nanowire, a lipid bilayer around the nanotube or nanowire, and a sensing element connected to the lipid bilayer. Also a biosensor apparatus comprising a gate electrode; a source electrode; a drain electrode; a nanotube or nanowire operatively connected to the gate electrode, the source electrode, and the drain electrode; a lipid bilayer around the nanotube or nanowire, and a sensing element connected to the lipid bilayer. |
| FILED | Tuesday, February 10, 2009 |
| APPL NO | 12/368382 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/213 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746979 | Dilmanian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | F. Avraham Dilmanian (Yaphank, New York); David J. Anchel (Rocky Point, New York); Glenn Gaudette (Holden, Massachusetts); Pantaleo Romanelli (Monteroduni, Italy); James Hainfeld (Shoreham, New York) |
| ABSTRACT | A method of assisting recovery of an injury site of the central nervous system (CNS) or treating a disease includes providing a therapeutic dose of X-ray radiation to a target volume through an array of parallel microplanar beams. The dose to treat CNS injury temporarily removes regeneration inhibitors from the irradiated site. Substantially unirradiated cells surviving between beams migrate to the in-beam portion and assist recovery. The dose may be staggered in fractions over sessions using angle-variable intersecting microbeam arrays (AVIMA). Additional doses are administered by varying the orientation of the beams. The method is enhanced by injecting stem cells into the injury site. One array or the AVIMA method is applied to ablate selected cells in a target volume associated with disease for palliative or curative effect. Atrial fibrillation is treated by irradiating the atrial wall to destroy myocardial cells while continuously rotating the subject. |
| FILED | Friday, February 10, 2006 |
| APPL NO | 11/884158 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747895 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles Jens Archer (Rochester, Minnesota); Kurt Walter Pinnow (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian Edward Smith (Rochester, Minnesota) |
| ABSTRACT | An apparatus, program product and method checks for nodal faults in a group of nodes comprising a center node and all adjacent nodes. The center node concurrently communicates with the immediately adjacent nodes in three dimensions. The communications are analyzed to determine a presence of a faulty node or connection. |
| FILED | Tuesday, July 01, 2008 |
| APPL NO | 12/165732 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07743928 | Crowley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Crowley (Phoenix, Arizona); Vincent B. Pizziconi (Phoenix, Arizona) |
| ABSTRACT | A passive self energized, liquid device operates entirely on capillary action. A microfilter fractionates nanoliter volumes of suspension such as whole blood into suspended particles or cells and liquid fractions. Blood, for example, is fractionated with minimal cell lysis, and the filtrate (plasma) flux is dependent upon design parameters similar to factors controlling blood filtration in microporous membranes, i.e. active filter area, fluid velocity and microfilter geometry. Weir-style filters communicate with a blood flow channel to separate plasma from blood moving by capillary action. An expanded downstream channel with multiple parallel capillary blood flow path provides continuing movement of blood past the filters. Lysing is controlled by the size of the filter pores and the duration of adherence of the red blood cells to the pores. The controlled lysis or prevention of lysis of red blood cells is accomplished by manipulating the significant capillary forces generated in the filters. Filtration, cell lysis and microchannel blood flow models are integrated into an overall microfilter design useful for fabricating microfilter devices for lab-on-a-chip clinical applications where they can be coupled with on-chip electrical and electro-optical devices. |
| FILED | Monday, September 08, 2003 |
| APPL NO | 10/658447 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid purification or separation 210/433.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744673 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Xingmao Jiang (Albuquerque, New Mexico); Charles Jeffrey Brinker (Albuquerque, New Mexico) |
| ABSTRACT | In accordance with invention, there are methods for fabricating hollow spheres and nanofoams. The method for making hollow spheres can include providing a homogeneous precursor solution including a first solvent and one or more anhydrous precursor species and forming aerosol droplets having a first size distribution using the homogeneous precursor solution in an anhydrous carrier gas. The method can also include transporting the aerosol droplets through an aerosol reactor including a reactant to form a plurality of hollow spheres, wherein each of the plurality of hollow spheres can be formed by one or more chemical reactions occurring at a surface of the aerosol droplet. The method can further include controlling size and thickness of the hollow spheres by one or more of the precursor solution concentration, aerosol droplet size, temperature, residence time of the aerosol droplets in the aerosol reactor, and the reactant distribution in the aerosol reactor. |
| FILED | Monday, October 22, 2007 |
| APPL NO | 11/876338 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/348 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744762 | Lazar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Iuliana M. Lazar (Blacksburg, Virginia) |
| ABSTRACT | The present invention provides a microfluidic device and method for facilitating on-chip complex sample processing and detection. In general, the device comprises at least a separation channel of a separation system, an interface, and an array of microreservoirs disposed within the same chip. The interface is configured to orthogonally transfer separated components from the separation channel into the array of microreservoirs, enabling direct analyte detection from the chip and high-throughput analysis. |
| FILED | Thursday, August 24, 2006 |
| APPL NO | 11/466818 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid purification or separation 210/656 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745001 | Rosenzweig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of New Orleans Research and Technology Foundation, Inc. (New Orleans, Louisiana) |
| INVENTOR(S) | Zeev Rosenzweig (New Orleans, Louisiana); Yongfen Chen (Fayetteville, Arkansas); Desheng Wang (Milwaukee, Wisconsin) |
| ABSTRACT | Negatively charged luminescent CdSe—ZnS quantum dots (QDs) were successfully incorporated into novel luminescent glyconanospheres averaging around 190 nm in diameter through electrostatic interactions with carboxymethyldextran (CM-dextran) and polylysine. The glyconanospheres preferably contain as well carboxyl-modified iron oxide nanocrystals. In addition to electrostatic attraction between the negatively charged dextran, the negatively charged CdSe—ZnS QDs (and negatively charged iron oxide nanocrystals, if present), and the positively charged polylysine, covalent amide bonds were introduced to cross link the QDs (and negatively charged iron oxide nanocrystals, if present) with the polysaccharide matrix to further stabilize the glyconanospheres. The dextran residues on the surface of the nanospheres show high affinity toward the glucose binding protein-Concanavalin A (Con A). As a result, these luminescent CdSe—ZnS QD incorporated glyconanospheres are a useful tool for studying carbohydrate-protein interactions that are critical steps in bacterial and viral infection. |
| FILED | Wednesday, March 23, 2005 |
| APPL NO | 11/088242 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745100 | Kohl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Paul A. Kohl (Atlanta, Georgia); SueAnn Bidstrup Allen (Atlanta, Georgia); Xiaoqun Wu (Wilmington, Delaware); Clifford Lee Henderson (Douglasville, Georgia) |
| ABSTRACT | Polymers, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary polymer, among others, includes, a photodefinable polymer having a sacrificial polymer and a photoinitiator. |
| FILED | Monday, June 12, 2006 |
| APPL NO | 11/451144 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745162 | Lauth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Intrinsic Lifesciences (La Jolla, California) |
| INVENTOR(S) | Xavier Lauth (San Diego, California); Mark E. Westerman (San Diego, California); Vaughn E. Ostland (La Quinta, California); Jason A. Stannard (San Diego, California); Michael W. Pennington (Mount Laurel, New Jersey) |
| ABSTRACT | The invention provides compositions and methods for measuring human serum hepcidin levels. The invention provides methods for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal. |
| FILED | Tuesday, November 11, 2008 |
| APPL NO | 12/268964 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.930 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745206 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Hongda Wang (Changchun, China PRC); Stuart Lindsay (Phoenix, Arizona) |
| ABSTRACT | An atomic force microscope and a method for detecting interactions between a probe and two or more sensed agents on a scanned surface and determining the relative location of two or more sensed agents is provided. The microscope has a scanning probe with a tip that is sensitive to two or more sensed agents on said scanned surface; two or more sensing agents tethered to the tip of the probe; and a device for recording the displacement of said probe tip as a function of time, topographic images, and the spatial location of interactions between said probe and the two or more sensed agents on said surface. |
| FILED | Tuesday, January 29, 2008 |
| APPL NO | 12/022072 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745220 | Abbott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Brian H. Clare (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides devices and methods for detection of analytes based on measuring the anchoring strength of liquid crystals having distorted geometries. Methods for detecting an analyte in a sample include the steps of: (a) capturing an analyte on a substrate surface wherein the substrate surface defines an easy axis when in contact with a liquid crystal. Substrate surface and liquid crystal are brought into contact and an analyte-dependent departure in the orientation of the liquid crystal from the easy axis of the substrate surface is measured. This departure indicates the presence of the analyte in the sample. |
| FILED | Tuesday, October 03, 2006 |
| APPL NO | 11/542432 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745377 | Hahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Klaus M. Hahn (Chapel Hill, North Carolina); Alexei Toutchkine (Chapel Hill, North Carolina); Rajeev Muthyala (Flushing, New York); Vadim Kraynov (San Diego, California); Steven J. Bark (San Diego, California); Dennis R. Burton (La Jolla, California); Chester Chamberlain (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides peptide synthons having protected functional groups for attachment of desired moieties (e.g. functional molecules or probes). Also provided are peptide conjugates prepared from such synthons, and synthon and conjugate preparation methods including procedures for identifying the optimum probe attachment site. Biosensors are provided having environmentally sensitive dyes that can locate specific biomolecules within living cells and detect chemical and physiological changes in those biomolecules as the living cell is moving, metabolizing and reacting to its environment. Methods are included for detecting GTP activation of a Rho GTPase protein using polypeptide biosensors. When the biosensor binds GTP-activated Rho GTPase protein, the environmentally sensitive dye emits a signal of a different lifetime, intensity or wavelength than when not bound. New fluorophores whose fluorescence responds to environmental changes are also provided that have improved detection and attachment properties, and that can be used in living cells, or in vitro. |
| FILED | Thursday, May 05, 2005 |
| APPL NO | 11/122795 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745528 | Prud'Homme et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Robert Prud'Homme (Lawrenceville, New Jersey); Bulent Ozbas (North Bergen, New Jersey); Ilhan Aksay (Princeton, New Jersey); Richard Register (Princeton Jct., New Jersey); Douglas Adamson (Skillman, New Jersey) |
| ABSTRACT | A polymer composition, containing a polymer matrix which contains an elastomer; and a functional graphene which displays no signature of graphite and/or graphite oxide, as determined by X-ray diffraction, exhibits excellent strength, toughness, modulus, thermal stability and electrical conductivity. |
| FILED | Friday, October 06, 2006 |
| APPL NO | 11/543872 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 524/495 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745594 | Seelig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Georg Seelig (Pasadena, California); David Soloveichik (Los Angeles, California); Erik Winfree (Altadena, California); David Zhang (Overland Park, Kansas) |
| ABSTRACT | This invention relates to nucleic acid-based logic gates. The invention further relates to circuits comprising nucleic acid-based logic gates and methods of performing operations with the gates and circuits provided herein. |
| FILED | Friday, July 21, 2006 |
| APPL NO | 11/490948 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745708 | Stupp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Jeffrey D. Hartgerink (Pearland, Texas); Elia Beniash (Auburndale, Massachusetts) |
| ABSTRACT | Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. |
| FILED | Friday, September 28, 2007 |
| APPL NO | 11/863975 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Nanotechnology 977/705 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745820 | Berger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Ohio State University (Columbus, Ohio) |
| INVENTOR(S) | Paul R. Berger (Columbus, Ohio); Woo-Jun Yoon (Columbus, Ohio) |
| ABSTRACT | A device includes: a first electrical contact; a second electrical contact; a semiconducting or semimetallic organic layer disposed at least partially between the first and second electrical contacts; and a tunneling barrier layer disposed at least partially between the semiconducting or semimetallic organic layer and the first electrical contact. The tunneling barrier layer has a thickness effective to enable flow of an electrical current through the tunneling barrier layer responsive to an operative electrical bias applied across the first and second electrical contacts, the electrical current exhibiting negative differential resistance for at least some applied electrical bias values. Circuits are also disclosed that utilize one or more negative differential resistance polymer diodes to implement logic, memory, or mixed signal applications. |
| FILED | Friday, November 03, 2006 |
| APPL NO | 11/592419 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747274 | Mickle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Marlin H. Mickle (Pittsburgh, Pennsylvania); Joshua Y. Maina (Pittsburgh, Pennsylvania); Michael R. Lovell (Wexford, Pennsylvania); Laura A. Schaefer (Pittsburgh, Pennsylvania) |
| ABSTRACT | Amplitude modulation of multiple carriers provides a pulse width modulated train resulting in a novel and effective communication mechanism to overcome difficulties in certain RF applications, particularly in the area of Radio Frequency Identification (RFID). A novel conceptual pulse is formed and developed using a set of RF frequencies, such as ultra wideband frequencies, amplitude modulated to form a pulse width modulated binary coded signal. The concept is to wirelessly convey information only to a receiver at a specified distance or range. The RF energy may continue on in space, but receivers of the same design would only receive information from a transmitter if the receivers are located at a specified distance. Equivalent receivers at all other distances would see noise. |
| FILED | Friday, September 28, 2007 |
| APPL NO | 11/863655 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/522 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747841 | Martinez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jose F. Martinez (Ithaca, New York); Meyrem Kirman (Ithaca, New York); Nevin Kirman (Ithaca, New York) |
| ABSTRACT | A technique known as checkpointed early load retirement, combines register checkpointing load-value prediction to manage long-latency loads. When a long-latency load reaches the retirement stage unresolved, the processor enters Clear mode by (1) taking a Checkpoint of the architectural registers, (2) supplying a load-value prediction to consumers, and (3) early-retiring the long-latency load. This unclogs retirement, thereby “clearing the way” for subsequent instructions to retire, and also allowing instructions dependent on the long-latency load to execute sooner. When the actual value returns from memory, it is compared against the prediction. A misprediction causes the processor to roll back to the checkpoint, discarding all subsequent computation. |
| FILED | Tuesday, September 26, 2006 |
| APPL NO | 11/526568 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/218 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07744133 | Wood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sunpower, Inc. (Athens, Ohio) |
| INVENTOR(S) | James Gary Wood (Albany, Ohio); Joseph P. Carroll (Moorpark, California) |
| ABSTRACT | A clamping apparatus for allowing pre-close-out access to the head of a Stirling machine and facilitating subsequent close-out welding of the head. The head is axially separable into removable and fixed portions that engage each other. Each portion has an annular flange extending radially outwardly at its engaging end, and each flange has an annular groove. O-rings are seated in the grooves. A temporary sealing ring surrounds and engages the O-rings. Clamping rings seat against axially opposite sides of the abutting annular flanges. Fasteners draw the rings together, thereby drawing the fixed and removable portions of the head together and securing them against relative axial movement. For close-out of the machine, the clamping rings, temporary sealing ring, and O-rings are removed and the grooved annular flanges serve as weld reliefs for final hermetic close-out welding. |
| FILED | Tuesday, February 27, 2007 |
| APPL NO | 11/711379 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipe joints or couplings 285/368 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07744844 | Barrera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Enrique V. Barrera (Houston, Texas); Richard Wilkins (College Station, Texas); Meisha Shofner (Decatur, Georgia); Merlyn X. Pulikkathara (Houston, Texas); Ranjii Vaidyanathan (Stillwater, Oklahoma) |
| ABSTRACT | The present invention involves the interaction of radiation with functionalized carbon nanotubes that have been incorporated into various host materials, particularly polymeric ones. The present invention is directed to chemistries, methods, and apparatuses which exploit this type of radiation interaction, and to the materials which result from such interactions. The present invention is also directed toward the time dependent behavior of functionalized carbon nanotubes in such composite systems. |
| FILED | Friday, June 27, 2008 |
| APPL NO | 12/163752 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745027 | Mohajeri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Central Florida Research Foundation Inc. (Orlando, Florida) |
| INVENTOR(S) | Nahid Mohajeri (Rockledge, Florida); Gary Bokerman (Rapid City, Michigan); Ali Tabatabaie-Raissi (Melbourne, Florida) |
| ABSTRACT | A method of generating hydrogen includes the steps of providing an amine borane (AB) complex, at least one hydrogen generation catalyst, and a solvent, and mixing these components. Hydrogen is generated. The hydrogen produced is high purity hydrogen suitable for PEM fuel cells. A hydrolytic in-situ hydrogen generator includes a first compartment that contains an amine borane (AB) complex, a second container including at least one hydrogen generation catalyst, wherein the first or second compartment includes water or other hydroxyl group containing solvent. A connecting network permits mixing contents in the first compartment with contents in the second compartment, wherein high purity hydrogen is generated upon mixing. At least one flow controller is provided for controlling a flow rate of the catalyst or AB complex. |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859458 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745528 | Prud'Homme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Robert Prud'Homme (Lawrenceville, New Jersey); Bulent Ozbas (North Bergen, New Jersey); Ilhan Aksay (Princeton, New Jersey); Richard Register (Princeton Jct., New Jersey); Douglas Adamson (Skillman, New Jersey) |
| ABSTRACT | A polymer composition, containing a polymer matrix which contains an elastomer; and a functional graphene which displays no signature of graphite and/or graphite oxide, as determined by X-ray diffraction, exhibits excellent strength, toughness, modulus, thermal stability and electrical conductivity. |
| FILED | Friday, October 06, 2006 |
| APPL NO | 11/543872 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Synthetic resins or natural rubbers 524/495 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745815 | Bandara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sumith V. Bandara (Valencia, California); Sarath Gunapala (Stevenson Ranch, California); John K. Liu (Pasadena, California) |
| ABSTRACT | A quantum well infrared photodetector (QWIP) focal plane array having structures, each structure having stacked layers of quantum wells and a reflective grating to provide polarization sensitivity. The reflective grating is etched to provide electrical contacts for individual pixels. The reflective gratings comprise grooves, where the grooves for a particular structure run in a particular direction to provide polarization sensitivity. Each structure may comprise groups of quantum well layers, each group sensitive to a particular frequency band. By shorting out unwanted quantum well layers, and by forming the reflective gratings to come into contact with the quantum well layers having a particular frequency band sensitivity, the pixels in the QWIP focal plane array may provide frequency and polarization information. |
| FILED | Tuesday, January 16, 2007 |
| APPL NO | 11/653785 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746190 | Vanin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Felice M. Vanin (Rome, Italy); Edward J. Wollack (Clarksville, Maryland) |
| ABSTRACT | A microwave waveguide filter includes an input waveguide section, an output waveguide section, a plurality of resonator sections disposed between the input and output waveguide sections, and a plurality of coupling sections disposed on either side of each of the resonator sections. The input waveguide section, the resonator sections, and the output waveguide section have at least four fold symmetric quadruple ridge cross-sections and the coupling sections have at least four fold symmetric cross-sections. |
| FILED | Tuesday, May 15, 2007 |
| APPL NO | 11/748969 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/21.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746266 | Zoughi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Reza Zoughi (Wildwood, Missouri); Mohamed Ahmed AbouKhousa (Rolla, Missouri); Mohammad Tayeb Ahmad Ghasr (Rolla, Missouri); Sergiy Kharkivskiy (Rolla, Missouri); David Pommerenke (Rolla, Missouri) |
| ABSTRACT | A sensor array having a plurality of modulated slots for microwave and/or millimeter wave imaging. The locations of the slots in the array define a spatial domain away from an object for detecting an electric field from the object. Each of the slots outputs a signal representative of the measured field and the location of the slot. A processor decodes the signals and generates an image of the object. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/052589 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746383 | Pain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Bedabrata Pain (Los Angeles, California); Thomas J. Cunningham (Pasadena, California); Bruce Hancock (Altadena, California); Suresh Seshadri (Cerritos, California); Monico Ortiz (Goleta, California); Guang Yang (Annandale, New Jersey) |
| ABSTRACT | The present invention provides a CMOS imager with a reset scheme, by which a CMOS imager generates a sub-kTC noise so that read noise does not depend on the sense node capacitance. By using a column feedback circuit, reset noise can be suppressed to a negligible amount so that photogate APS or CCD-like circuits can achieve noise performance to very efficient value. This scheme allows increasing sense node capacitance without increasing the noise and also achieves a large full-well value without sacrificing read noise performance. The feedback circuit in one of the embodiment of the present invention is located at the column side of the circuit. This design provides a minimal change to the pixel. As a result quantum efficiency or pixel size is not compromised. The present invention allows a CMOS imager to capture scene with high intra-scene contracts under low illumination with high dynamic range. |
| FILED | Thursday, February 12, 2004 |
| APPL NO | 10/779144 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/216.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07743715 | Becker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Gunderson LLC (Portland, Oregon); The State of Oregon, on behalf of Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Bruce D. Becker (Vancouver, Washington); Deborah V. Pence (Corvallis, Oregon) |
| ABSTRACT | An air flow conduit (98) and a related plenum (80) for distributing conditioned air from a refrigeration and heating unit (64) on an end (44) of a railroad freight car (20) into a cargo space (53) within the car (20). A deflector directs a flow of air upward into an inlet end of the plenum (80) and allows the flow to expand gradually within the plenum, smoothing the flow of air within the plenum so that it continues effectively at sufficient rates over the length of the car (20). |
| FILED | Thursday, May 13, 2004 |
| APPL NO | 11/596386 |
| ART UNIT | 3617 — Printing/Measuring and Testing |
| CURRENT CPC | Railway rolling stock 15/404 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745215 | Shirwan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Haval Shirwan (Louisville, Kentucky) |
| ABSTRACT | The present invention provides methods and compositions for expanding Treg cells ex vivo or in vivo using one or more conjugates comprising a costimulatory moiety that stimulates at least one of three signals involved in Treg cell development and/or using dendritic cells pulsed with antigens and modified to display TGF-β, or hematopoetic stem cells or bone marrow cells modified to display TGF-β. The methods and compositions are useful, for example, in the treatment and prevention of autoimmune disease, including Type 1 diabetes and in preventing foreign graft rejection, as well as to establish mixed chimerism, induce tolerance to autoantigens, alloantigens or xenoantigens, beta cell regeneration, prevention of foreign graft rejection, and treatment of a genetically inherited hematopoietic disorder. |
| FILED | Thursday, December 07, 2006 |
| APPL NO | 11/635087 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745574 | Satterthwait et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Arnold Satterthwait (San Diego, California); Xiao-kun Zhang (San Diego, California); Xiuwen Zhu (San Diego, California); Siva Kolluri (San Diego, California) |
| ABSTRACT | Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and related Bcl-2 family members are identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing or preventing apoptosis are described, together with methods for identifying molecules that induce or prevent apoptosis through interaction with Bcl-2-family members. Methods for treatment of proliferative diseases and neurodegenerative diseases using the modulators of Bcl-2 and related family members are also disclosed. |
| FILED | Thursday, May 11, 2006 |
| APPL NO | 11/433783 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746452 | Fuchigami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Leslie H. Fuchigami (Corvallis, Oregon); Pinghai Ding (Burnaby, Canada); Guy E. Barnes, Jr. (Hillsboro, Oregon) |
| ABSTRACT | Methods for determining chlorophyll content comprise providing a sample, subjecting the sample to light at a first wavelength and detecting a first wavelength response, subjecting the sample to light at a second wavelength and detecting a second wavelength response, and calculating a chlorophyll content of the sample based on at least the first wavelength response and the second wavelength response. Optional approaches include detecting the nitrogen content and/or water content of the sample. Associated apparatus for determining chlorophyll content, which may comprise a handheld device, is also disclosed. |
| FILED | Tuesday, November 21, 2006 |
| APPL NO | 12/089902 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/73 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07745121 | Siegler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Katherine Siegler (Seminole, Florida); Kenneth Iczkowski (Gainesville, Florida); Richard Bucala (Cos Cob, Connecticut); Pedro L. Vera (Largo, Florida) |
| ABSTRACT | The present invention relates to the risk assessment, detection, diagnosis, or prognosis of prostate cancer. More specifically, this invention relates to the detection of certain polymorphism in the promoter region of the MIF gene to determine the risk, detect, diagnose, or prognosticate prostate cancer. Applicants have discovered that the presence of a −173C and/or −749 (CATT)7 or more repeat predispose an individual to prostate cancer. |
| FILED | Tuesday, May 23, 2006 |
| APPL NO | 11/438370 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745402 | Omary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lundbeck Inc. (Deerfield, Illinois) |
| INVENTOR(S) | Bishr Omary (Mountain View, California); Stephen Collins (Lake Forest, Illinois) |
| ABSTRACT | The present invention provides a method of treating pancreatitis comprising administering to a human in need thereof an effective amount of hemin. The administration of hemin is preferably parenteral. In another aspect, the present invention provides a method of pancreatitis prophylaxis comprising administering to a human in need thereof an effective amount of hemin. In a still further aspect, the present invention contemplates a method of inducing an HO gene comprising administering to a human in need thereof an HO-inducing effective amount of hemin. Preferably, the HO gene is the HO-1 gene. In a still further aspect, the present invention contemplates a method of inducing an HO gene in leukocytes for recruitment to the pancreas to treat pancreatitis comprising administering to a human in need thereof an HO-inducing effective amount of hemin. In another embodiment, the present invention contemplates a method of inducing an HO gene in leukocytes for recruitment to the pancreas for prophylaxis of pancreatitis comprising administering to a human in need thereof an HO-inducing effective amount of hemin. In a yet further aspect, the present invention provides a method of ex vivo treatment of pancreatitis comprising providing peripheral blood leukocytes, followed by contact with hemin to form induced peripheral blood leukocytes then infusing the induced peripheral blood leukocytes into a human in need thereof. |
| FILED | Monday, October 02, 2006 |
| APPL NO | 11/542522 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745691 | Farese, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Robert V. Farese, Jr. (Kentfield, California); Hubert C. Chen (Newbury Parl, California); Steven J. Smith (San Francisco, California); Sylvaine Cases (Belmont, California); Sandra K. Erickson (San Francisco, California) |
| ABSTRACT | Methods and compositions for modulating carbohydrate metabolism in a host are provided. In the subject methods, diacylglycerol acyltransferase (DGAT) activity (specifically DGAT1 activity) is modulated, e.g., reduced or enhanced, to achieve a desired insulin and/or leptin sensitivity, thereby modulating carbohydrate metabolism, e.g., increasing or decreasing blood glucose levels, glucose uptake into cells and assimilation into glycogen. Also provided are pharmaceutical compositions for practicing the subject methods. The subject methods and compositions find use in a variety of applications, including the treatment of hosts suffering conditions associated with abnormal carbohydrate metabolism, such as obesity or diabetes. |
| FILED | Tuesday, December 12, 2006 |
| APPL NO | 11/609810 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07745602 | Bughrara |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Suleiman Bughrara (East Lansing, Michigan) |
| ABSTRACT | The present inventions relate to compositions and methods for providing drought resistant grass plants comprising Festuca mairei plant germplasm. Specifically, the inventions relate to providing compositions and methods for introgressing Festuca mairei germplasm and/or specific Festuca mairei genes into grass plants, such as Lolium perenne plants. Further, the invention relates to methods of grass plant breeding comprising genetic markers for identifying the preferred Festuca mairei germplasm introgressed into grass plants, and providing commercially desirable drought resistant cultivars of grass plants. |
| FILED | Thursday, February 07, 2008 |
| APPL NO | 12/069402 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745698 | Ziegelhoffer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Thomas Ziegelhoffer (Madison, Wisconsin); Sandra Austin-Phillips (Madison, Wisconsin) |
| ABSTRACT | The invention provides a novel method of controlling gene expression in plastids, using a peptide extension that can be fused to a desired protein, expression cassettes that include the genetic constructs, and plants comprising the novel expression systems. A nucleic acid sequence encoding a peptide extension fused in frame to a protein coding sequence. This genetic construct is subsequently inserted into the chloroplast genome, where the peptide extension increases expression of the fused protein. The present invention further describes the use of this method for increased production of cellulose-degrading enzymes in chloroplasts. |
| FILED | Thursday, November 16, 2006 |
| APPL NO | 11/600566 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/298 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07744844 | Barrera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Enrique V. Barrera (Houston, Texas); Richard Wilkins (College Station, Texas); Meisha Shofner (Decatur, Georgia); Merlyn X. Pulikkathara (Houston, Texas); Ranjii Vaidyanathan (Stillwater, Oklahoma) |
| ABSTRACT | The present invention involves the interaction of radiation with functionalized carbon nanotubes that have been incorporated into various host materials, particularly polymeric ones. The present invention is directed to chemistries, methods, and apparatuses which exploit this type of radiation interaction, and to the materials which result from such interactions. The present invention is also directed toward the time dependent behavior of functionalized carbon nanotubes in such composite systems. |
| FILED | Friday, June 27, 2008 |
| APPL NO | 12/163752 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745215 | Shirwan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Haval Shirwan (Louisville, Kentucky) |
| ABSTRACT | The present invention provides methods and compositions for expanding Treg cells ex vivo or in vivo using one or more conjugates comprising a costimulatory moiety that stimulates at least one of three signals involved in Treg cell development and/or using dendritic cells pulsed with antigens and modified to display TGF-β, or hematopoetic stem cells or bone marrow cells modified to display TGF-β. The methods and compositions are useful, for example, in the treatment and prevention of autoimmune disease, including Type 1 diabetes and in preventing foreign graft rejection, as well as to establish mixed chimerism, induce tolerance to autoantigens, alloantigens or xenoantigens, beta cell regeneration, prevention of foreign graft rejection, and treatment of a genetically inherited hematopoietic disorder. |
| FILED | Thursday, December 07, 2006 |
| APPL NO | 11/635087 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07744844 | Barrera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Enrique V. Barrera (Houston, Texas); Richard Wilkins (College Station, Texas); Meisha Shofner (Decatur, Georgia); Merlyn X. Pulikkathara (Houston, Texas); Ranjii Vaidyanathan (Stillwater, Oklahoma) |
| ABSTRACT | The present invention involves the interaction of radiation with functionalized carbon nanotubes that have been incorporated into various host materials, particularly polymeric ones. The present invention is directed to chemistries, methods, and apparatuses which exploit this type of radiation interaction, and to the materials which result from such interactions. The present invention is also directed toward the time dependent behavior of functionalized carbon nanotubes in such composite systems. |
| FILED | Friday, June 27, 2008 |
| APPL NO | 12/163752 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745047 | Zhamu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Aruna Zhamu (Centerville, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | The present invention provides a nano-scaled graphene platelet-based composite material composition for use as an electrode, particularly as an anode of a lithium ion battery. The composition comprises: (a) micron- or nanometer-scaled particles or coating which are capable of absorbing and desorbing lithium ions; and (b) a plurality of nano-scaled graphene platelets (NGPs), wherein a platelet comprises a graphene sheet or a stack of graphene sheets having a platelet thickness less than 100 nm; wherein at least one of the particles or coating is physically attached or chemically bonded to at least one of the graphene platelets and the amount of platelets is in the range of 2% to 90% by weight and the amount of particles or coating in the range of 98% to 10% by weight. Also provided is a lithium secondary battery comprising such a negative electrode (anode). The battery exhibits an exceptional specific capacity, an excellent reversible capacity, and a long cycle life. |
| FILED | Monday, November 05, 2007 |
| APPL NO | 11/982672 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/231.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07744717 | Andrews et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | E. I. du Pont de Nemours and Company (Wilmington, Delaware) |
| INVENTOR(S) | Gerald Donald Andrews (Hockessin, Delaware); Richard Kevin Bailey (Newark, Delaware); Graciela Beatriz Blanchet (Wilmington, Delaware); John W. Catron (Smyrna, Delaware); Feng Gao (Hockessin, Delaware); Gary Delmar Jaycox (West Chester, Pennsylvania); Lynda Kaye Johnson (Wilmington, Delaware); Roupen Leon Keusseyan (Raleigh, North Carolina); Jeffrey Scott Meth (Landenberg, Pennsylvania); Frank S. Principe (Landenberg, Pennsylvania); Rinaldo S. Schiffino (Wilmington, Delaware); Robert Mar Yohannan (Rutledge, Pennsylvania) |
| ABSTRACT | Provided are processes for enhancing the resolution of a thermally transferred pattern on an imaged thermal transfer receiver, wherein the imaged thermal transfer receiver comprises a surface having an exposed portion and a non-exposed portion of one or more thermally transferred layer(s), comprising: (a) contacting said surface with an adhesive layer for a contact period to provide a laminate; (b) separating said adhesive layer from the laminate to provide a treated thermal transfer receiver having a surface substantially free of said non-exposed portion of one or more thermally transferred layer(s). The processes are useful in the fabrication of electronic devices including thin film transistors, circuits, electromagnetic interference shields, touchpad sensors and other electronic devices. |
| FILED | Wednesday, April 25, 2007 |
| APPL NO | 11/789842 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/247 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 07745207 | Jovanovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | IntegenX, Inc. (Pleasanton, California) |
| INVENTOR(S) | Stevan B. Jovanovich (Livermore, California); Iuliu I. Blaga (Fremont, California) |
| ABSTRACT | Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense. |
| FILED | Friday, February 02, 2007 |
| APPL NO | 11/670866 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 07744773 | Shih et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Hongyu Luo (Duncan, Oklahoma); Christian Martorano (Marlton, New Jersey); Wan Y. Shih (Bryn Mawr, Pennsylvania) |
| ABSTRACT | A method to produce low-temperature sinterable powders which are then subsequently used to fabricate freestanding piezoelectric films with very large electric-field-enhanced piezoelectric response is provided. The −d31 coefficient for PMN-PT layers can be as high as 2000 pm/V, larger than that of commercial single crystalline PMN-PT bulk materials, at 10 kV/cm (or 20 V over the 20-micron film thickness). In contrast to single crystals, the polycrystalline freestanding films are easy to fabricate and can be made into any size. The films are also easily miniaturized. The method can be applied to nearly any piezoelectric material. |
| FILED | Wednesday, March 29, 2006 |
| APPL NO | 11/392116 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Compositions 252/62.9R0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07747670 | Hussain |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (, None) |
| INVENTOR(S) | Khalid Hussain (Gladstone, Missouri) |
| ABSTRACT | Creating a customized item cover comprises receiving customization data and creating at least one customization segment using the customization data. In addition, creating a customized item cover includes producing the customized item cover including the at least one customization segment. Producing the customized item cover may comprise printing the at least one customization segment on the customized item cover or embossing the at least one customization segment on the customized item cover. |
| FILED | Tuesday, September 17, 2002 |
| APPL NO | 10/245424 |
| ART UNIT | 2457 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07745116 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | John G. K. Williams (Lincoln, Nebraska) |
| ABSTRACT | The present invention provides compositions and methods for detecting incorporation of a labeled nucleotide triphosphate onto the growing end of a primer nucleic acid molecule. The method is used, for example, to genotype and sequence a nucleic acid. In a preferred embodiment, the method described herein detects individual NTP molecules. |
| FILED | Thursday, April 08, 2004 |
| APPL NO | 10/821689 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745150 | Liang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Bruce Tsan-Tang Liang (Avon, Connecticut); W. David Hager (Bloomfield, Connecticut) |
| ABSTRACT | Disclosed herein are methods of detecting and/or prognosing congestive heart failure by detecting a proteolytic fragment of caspase-3 such as the p17 fragment or the p12 fragment. The congestive heart failure can be of any etiology, such as systolic or diastolic heart failure, ischemic or non-ischemic cardiomyopathy. |
| FILED | Monday, March 09, 2009 |
| APPL NO | 12/400061 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745597 | Winn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michelle Winn (Durham, North Carolina); Margaret A. Pericak-Vance (Durham, North Carolina); Jeffery M. Vance (Chapel Hill, North Carolina) |
| ABSTRACT | Focal and segmental glomerulosclerosis (FSGS) is a kidney disorder of unknown etiology and up to 20% of patients on dialysis have this diagnosis. A large family with hereditary FSGS carries a missense mutation in the TRPC6 gene on chromosome 11q, encoding the ion channel protein Transient Receptor Potential Cation Channel 6. The missense mutation is a P112Q substitution, which occurs in a highly conserved region of the protein, enhances TRPC6-mediated calcium signals in response to agonists such as angiotensin II, and alters the intracellular distribution of TRPC6 protein. Previous work has emphasized the importance of cytoskeletal and structural proteins in proteinuric kidney diseases. Our findings suggest a novel mechanism for glomerular disease pathogenesis. |
| FILED | Friday, March 09, 2007 |
| APPL NO | 11/716050 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07745635 | Drake et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Greg W. Drake (Palmdale, California); Tommy Hawkins (Lancaster, California); Kerri Tollison (Lancaster, California) |
| ABSTRACT | The invention provides a) a method for making improved ionic halide salts, e.g., 1-methyl-4-amino-1,2,4-triazolium iodide and b) a method for making energetic ionic salts, e.g., 1-methyl-4-amino-1,2,4-triazolium nitrate, in high yield and purity from triazolium precursors. Also provided are the resulting novel salts from the above methods. |
| FILED | Monday, June 16, 2003 |
| APPL NO | 10/465836 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/265.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07746515 | Straka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Microvision, Inc. (Redmond, Washington) |
| INVENTOR(S) | Scott Straka (Kirkland, Washington); Jari Honkanen (Monroe, Washington); Philip C. Black (Woodbridge, Connecticut); James G. Moore (Guilford, Connecticut) |
| ABSTRACT | A circuit for detecting a phase error between a clock signal and a beam position includes a beam generator, sensor, and phase detector. The beam generator directs a beam toward a beam sweeper in response to a clock signal. The sensor, which is disposed at a mid line of a region that the beam sweeper scans, detects the beam from the beam sweeper, and the phase detector detects an error in the clock phase from the detected beam. Such a circuit can automatically detect the phase error in the pixel clock and correct this error, thus eliminating the need for a manual phase-error corrector. |
| FILED | Wednesday, December 21, 2005 |
| APPL NO | 11/316326 |
| ART UNIT | 2625 — Selective Visual Display Systems |
| CURRENT CPC | Facsimile and static presentation processing 358/474 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747068 | Smyth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Paul Smyth (Fallston, Maryland); Christopher Charles Smyth (Fallston, Maryland) |
| ABSTRACT | Disclosed are systems and methods for tracking the eye. In one embodiment, a method for tracking the eye includes acquiring stereo images of the eye using multiple sensors, isolating internal features of the eye in the stereo images acquired from the multiple sensors, and determining an eye gaze direction relative to the isolated internal features. |
| FILED | Friday, January 20, 2006 |
| APPL NO | 11/340821 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07747106 | Spence et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sarnoff Corporation (Princeton, New Jersey) |
| INVENTOR(S) | Clay Douglas Spence (Princeton Junction, New Jersey); Craig Langdale Fancourt (Lawrenceville, New Jersey) |
| ABSTRACT | An iterative approach to vector median filtering wherein the resulting median vector need not be a member of the original data set. The iterative vector median filtering allows for fast convergence for complex computations and an output which is approximate to the mean, particularly for small data sets. In addition, a method and system for registering and matching 2.5 normal maps is provided. Registration of two maps is performed by optimally aligning their normals through 2-D warping in the image plane in conjunction with a 3-D rotation of the normals. Once aligned, the average dot-product serves as a matching metric for automatic target recognition (ATR). |
| FILED | Tuesday, June 13, 2006 |
| APPL NO | 11/451671 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/296 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07748040 | Adelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| INVENTOR(S) | Frank N. Adelstein (Ithaca, New York); Haim Bar (Ithaca, New York); Prasanth Alla (McLean, Virginia); Nikita Proskourine (Plainville, Massachusetts) |
| ABSTRACT | Techniques are described for providing security to a protected network. Techniques are described for thwarting attempted network attacks using marked information. The attack correlation system provides marked information to computing devices that probe for sensitive information, and monitors subsequent communications for use of the marked information. In one example, the attack correlation system reroutes communications containing the marked information to a dedicated vulnerable device that logs the communications to monitor the attackers' methods. The attack correlation system may also include functionality to exchange information regarding attempted attacks with other attack correlation systems to gain broader knowledge of attacks throughout one or more networks. |
| FILED | Tuesday, March 22, 2005 |
| APPL NO | 11/087388 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Information security 726/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 29, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100629.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page