FedInvent™ Patents

Patent Details for Tuesday, July 06, 2010 

This page was updated on Monday, March 27, 2023 at 01:51 AM GMT

Department of Defense (DOD) 

US 07748272 Kranz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)
ASSIGNEE(S) Morgan Research Corporation (Huntsville, Alabama)
INVENTOR(S) Michael Scott Kranz (Madison, Alabama);  Robert Faye Elliot (Madison, Alabama);  Michael Ray Whitley (Madison, Alabama);  Marty Ray Williams (Huntsville, Alabama);  Philip John Reiner (Huntsville, Alabama)
ABSTRACT The MEMS Sensor Suite on a Chip provides the capability, monolithically integrated onto one MEMS chip, to sense temperature, humidity, and two axes of acceleration. The device incorporates a MEMS accelerometer, a MEMS humidity sensor, and a MEMS temperature sensor on one chip. These individual devices incorporate proof masses, suspensions, humidity sensitive capacitors, and temperature sensitive resistors (thermistors) all fabricated in a common fabrication process that allows them to be integrated onto one micromachined chip. The device can be fabricated in a simple micromachining process that allows its size to be miniaturized for embedded and portable applications. During operation, the sensor suite chip monitors temperature levels, humidity levels, and acceleration levels in two axes. External circuitry allows sensor readout, range selection, and signal processing.
FILED Thursday, March 20, 2008
APPL NO 12/051905
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/493
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07748486 Mantych et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International, Inc. (Morristown, New Jersey)
INVENTOR(S) Glen A. Mantych (Placitas, New Mexico);  Emray R. Goossen (Albuquerque, New Mexico)
ABSTRACT Self-leveling legs are used to accommodate landing a ducted fan hovercraft on a sloped surface such as a roof-top. These legs move to accommodate a variation of slope within their range of motion irrespective to the azimuth of the vehicle body. The configuration and operation of the landing legs allow the hovercraft to land in a stable fashion with the hovercraft vehicle body maintained in a vertical orientation. The basic kinematics of the present invention is the displacement of one landing leg upwards is connected by a horizontal member to the opposite leg and displaces it downwards, and visa-versa. Planar surface contact is accomplished by the unique curvature of the legs and the splay of the legs from the vehicle body.
FILED Wednesday, May 10, 2006
APPL NO 11/431792
ART UNIT 3611 — Printing/Measuring and Testing
CURRENT CPC
Motor vehicles
180/119
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US 07748663 Craig et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Curtis D. Craig (Carriere, Mississippi);  Derek A. Townsend (Slidell, Louisiana);  James P. Brady (Mandeville, Louisiana)
ABSTRACT A mating and connection system for securing adjacent stages of a launch vehicle. The system includes a locking flange connected to each of a first vehicle stage and a second vehicle stage. A compression ring is positioned internal to the first and second vehicle stages. The compression ring is shaped to compress together the locking flanges of the first and second stages upon engagement with the locking flanges. A locking jack is capable of being activated from an exterior of the first and second stages and operates to selectively move the compression ring into and out of engagement with the locking flanges.
FILED Tuesday, May 23, 2006
APPL NO 11/439786
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/158.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07748931 Drucker
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Andrew Scott Drucker (Newbury Park, California)
ABSTRACT A supplemental fluid adjustable depth air sparging system which is used to remediate contaminates from groundwater within the soil. An adjustable depth air injection point injects compressed air, and an adjustable depth chemical injection point injects a chemical oxidizer or nutrient into saturated or groundwater regions of the soil's subsurface to remove contaminants including chlorinated solvents from the soil's subsurface.
FILED Monday, September 10, 2007
APPL NO 11/852660
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Hydraulic and earth engineering
45/128.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07748952 Schopf et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Cheryl A. Schopf (Jupiter, Florida);  Jack W. Wilson, Jr. (Palm Beach Gardens, Florida)
ABSTRACT A small twin spool gas turbine engine with a bearing support arrangement in which the bearings are dampened by O-rings secured between the bearing races and the support structure, and in which the bearings are arranged in series so that a cooling air can be passed through the bearings to prevent overheating. The aft end of the engine includes high speed and low speed ball bearings supported with preload springs to add additional damping capability. The fore and aft end bearing support assemblies forms a cooling air path for the cooling fluid to flow through a passage within one of the guide vanes, through the bearings and out through a hole in the low pressure turbine rotor disk. the bearing cooling air passage includes a snorkel tube that extends from a guide vane cooling air passage and into the bypass air channel to draw in the cooling air used for the bearings. The snorkel tube includes a slanted opening so that dirt particulates do not enter the bearing cooling air passage.
FILED Friday, August 01, 2008
APPL NO 12/184885
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/116
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749299 Vanheusden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Cabot Corporation (Boston, Massachusetts)
INVENTOR(S) Karel Vanheusden (Placitas, New Mexico);  Klaus Kunze (Albuquerque, New Mexico);  Hyungrak Kiim (Albuquerque, New Mexico);  Aaron D. Stump (Albuquerque, New Mexico);  Allen B. Schult (Albuquerque, New Mexico);  Mark J. Hampden-Smith (Albuquerque, New Mexico);  Chuck Edwards (Rio Rancho, New Mexico);  Anthony R. James (Rio Rancho, New Mexico);  James Caruso (Albuquerque, New Mexico);  Toivo T. Kodas (Albuquerque, New Mexico);  Scott Thomas Haubrich (Albuquerque, New Mexico);  Mark H. Kowalski (Albuquerque, New Mexico)
ABSTRACT A process for the production of metal nanoparticles. The process comprises a rapid mixing of a solution of at least about 0.1 mole of a metal compound that is capable of being reduced to a metal by a polyol with a heated solution of a polyol and a substance that is capable of being adsorbed on the nanoparticles.
FILED Friday, January 13, 2006
APPL NO 11/331230
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/362
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US 07749344 Sengupta
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) CFO Research Corporation (Huntsville, Alabama)
INVENTOR(S) Debasis Sengupta (Madison, Alabama)
ABSTRACT Disclosed is a group of tertiary amine azides useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH.
FILED Tuesday, February 27, 2007
APPL NO 11/679672
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Explosive and thermic compositions or charges
149/1
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US 07749408 Jen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Kwan-Yue Jen (Kenmore, Washington);  Jingdong Luo (Seattle, Washington);  Tae-Dong Kim (Seattle, Washington);  Baoquan Chen (Bothell, Washington);  Jae-Wook Kang (Gyeongsangnam-do, South Korea);  Philip A. Sullivan (Seattle, Washington);  Andrew Akelaitis (Seattle, Washington);  Larry R. Dalton (Silverdale, Washington);  Yen-Ju Cheng (Seattle, Washington)
ABSTRACT A composite having electro-optic activity including a chromophore compound dispersed in a host material comprising a dendronized chromophore compound, methods for making the composite, and electro-optic devices including the composite.
FILED Thursday, August 03, 2006
APPL NO 11/462339
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/582
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US 07749438 Zeinali et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Mazyar Zeinali (Columbia, Maryland);  Brandy J White (Alexandria, Virginia);  Paul T Charles (Bowie, Maryland);  Michael A Markowitz (Springfield, Virginia)
ABSTRACT Periodic mesoporous organosilicas (PMO) which incorporate an optically active molecule into the material for use as an optical indicator of target binding. This material combines the stability, selectivity, and high density of binding sites characteristic of the PMO with the sensitivity and selectivity of the optically active molecule. The material undergoes a change when exposed to a sample containing a target molecule. The change can be observed by visual inspection or through the use of fluorescence spectra.
FILED Thursday, August 17, 2006
APPL NO 11/465343
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/57
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US 07749440 Genovese
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) James A. Genovese (Street, Maryland)
ABSTRACT Methods and apparatus for chemical warfare agent detection training are provided. More particularly, methods and apparatus are provided to simulate the detection of low volatility chemical warfare agents by simulating the use of currently fielded U.S. Army detection kits without exposure to hazardous agents. A simulant is disposed in a sample heating assembly. The sample heating assembly is placed over a detection window of a detector, and the simulant is heated in order to make a simulated detection.
FILED Thursday, January 12, 2006
APPL NO 11/340814
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/61
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US 07749443 Land, III
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) H. Bruce Land, III (Laurel, Maryland)
ABSTRACT The present invention is directed to an enhanced sampling device, herein referred to as an ESD, for enhancing the collection efficiency of the SPME method by enhancing the flow of the analytes onto the sampling fiber. The ESD includes a tubular main body, used for a sampling shroud, which directs a flow of analytes to contact the fiber during collection. One end of the main body is open and faces the sample, allowing analytes to flow into the ESD and contact the fiber. A second piece of tubing branches from the other end of the main body and becomes an outlet port, possibly leading to a pump. The ESD permits more rapid transport and absorption of the analytes to the fiber for collection.
FILED Monday, December 17, 2007
APPL NO 11/957837
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/69
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749511 Gustafson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) EndoBiologics, Incorporated (Missoula, Montana)
INVENTOR(S) Gary L. Gustafson (Missoula, Montana);  Dan C. DeBorde (Missoula, Montana)
ABSTRACT The present invention provides an immunogenic conjugate comprising biologically deacylated gram-negative bacterial moieties linked to D. discoideum proteinase 1, as well as novel subunits thereof, and methods of making and using the conjugates in vaccines to treat sepsis and other infectious complications.
FILED Tuesday, November 15, 2005
APPL NO 11/274847
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/234.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749603 Graham et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center (NAWC)
APPLICANT(S)
ASSIGNEE(S) Lumimove, Inc. (St. Louis, Missouri);  Brewer Science, Inc. (Rolla, Missouri)
INVENTOR(S) Charles R. Graham (St. Peters, Missouri);  Patrick J. Kinlen (Fenton, Missouri);  Tony D. Flaim (St. James, Missouri)
ABSTRACT A transparent two-layer electrostatic dissipating coating includes a first layer comprising a transparent first binder polymer and a first intrinsically conducting polymer (ICP) in an amount sufficient to provide the first layer with a surface resistance of from about 103 to about 105Ω/□; and a second layer in direct contact with the first layer and comprising a transparent second binder polymer and a second ICP in an amount sufficient to provide the second layer with a surface resistance of from about 106 to about 1010Ω/□, wherein the coating has a light transmission of at least about 70% at a wavelength of 600 nm. Methods of making and using the coating are also described.
FILED Monday, February 11, 2008
APPL NO 12/069457
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Stock material or miscellaneous articles
428/411.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749699 Kool
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Eric T. Kool (Stanford, California)
ABSTRACT Novel compounds having a fluorescence quencher as a leaving group are disclosed. Nucleic acids and other molecules containing a fluorophore and a fluorescence quencher are disclosed as an embodiment of this invention. The use of the oligonucleotides in enzyme-free oligonucleotide ligation reactions results in an increase in fluorescence when the oligonucleotide also contains a nearby fluorophore. The ligation reactions can be performed in solution, on surfaces, or in cells.
FILED Thursday, July 17, 2003
APPL NO 10/604400
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749792 Fedder et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Gary K. Fedder (Turtle Creek, Pennsylvania);  Altug Oz (Istanbul, Turkey)
ABSTRACT The present disclosure is broadly directed to a method for designing new MEMS micro-movers, particularly suited for, but not limited to, CMOS fabrication techniques, that are capable of large lateral displacement for tuning capacitors, fabricating capacitors, self-assembly of small gaps in CMOS processes, fabricating latching structures and other applications where lateral micro-positioning on the order of up to 10 μm, or greater, is desired. Principles of self-assembly and electro-thermal actuation are used for designing micro-movers. In self-assembly, motion is induced in specific beams by designing a lateral effective residual stress gradient within the beams. The lateral residual stress gradient arises from purposefully offsetting certain layers of one material versus another material. For example, lower metal layers may be side by side with dielectric layers, both of which are positioned beneath a top metal layer of a CMOS-MEMS beam. In electro-thermal actuation, motion is induced in specific beams by designing a lateral gradient of temperature coefficient of expansion (TCE) within the beams. The lateral TCE gradient is achieved in the same manner as with self-assembly, by purposefully offsetting the lower metal layers with layers of dielectric with respect to the top metal layer of a CMOS-MEMS beam. A heater resistor, usually made from a CMOS polysilicon layer, is embedded into the beam or into an adjacent assembly to heat the beam. When heated, the TCE gradient will cause a stress gradient in the beam, resulting in the electro-thermal actuation. Because of the rules governing abstracts, this abstract should not be used to construe the claims.
FILED Wednesday, June 02, 2004
APPL NO 10/558469
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749793 Elliott et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Morgan Research Corporation (Huntsville, Alabama)
INVENTOR(S) Robert Faye Elliott (Madison, Alabama);  Philip John Reiner (Huntsville, Alabama)
ABSTRACT A method of making a Lateral-Moving Micromachined Thermal Bimorph which provides the capability of achieving in-plane thermally-induced motion on a microchip, as opposed to the much more common out-of-plane, or vertical, motion seen in many devices. The present invention employs a novel fabrication process to allow the fabrication of a lateral bimorph in a fundamentally planar set of processes. In addition, the invention incorporates special design features that allow the bimorph to maintain material interfaces.
FILED Thursday, January 22, 2009
APPL NO 12/357826
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749872 Plummer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) James D. Plummer (Portola Valley, California);  Peter B. Griffin (Woodside, California);  Jia Feng (Palo Alto, California);  Shu-Lu Chen (Stanford, California)
ABSTRACT Single-crystalline growth is realized using a liquid-phase crystallization approach involving the inhibition of defects typically associated with liquid-phase crystalline growth of lattice mismatched materials. According to one example embodiment, a semiconductor device structure includes a substantially single-crystal region. A liquid-phase material, such as Ge or a semiconductor compound, is crystallized to form the single-crystal region using an approach involving defect inhibition for the promotion of single-crystalline growth. In some instances, this defect inhibition involves the reduction and/or elimination of defects using a relatively small physical opening via which a crystalline growth front propagates. In other instances, this defect inhibition involves causing a change in crystallization front direction relative to a crystallization seed location. The relatively small physical opening and/or the change in crystalline front direction may be implemented, for example, using a material that is substantially unreactive with the liquid-phase material to contain the crystalline growth.
FILED Wednesday, February 25, 2009
APPL NO 12/392261
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/479
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749962 Wieder
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) University of Medicine and Dentistry of NJ (New Brunswick, New Jersey)
INVENTOR(S) Robert Wieder (Westfield, New Jersey)
ABSTRACT The present invention provides for identification of agents that induce growth arrest and survival of cancer cells, which remain dormant in bone marrow, thus preventing their eradication through use of standard chemotherapy or radiation therapy. Basic fibroblast growth factor (FGF-2), a mammary differentiation factor abundant in the bone marrow stroma, induces growth arrest of relatively differentiated breast cancer cells and restricts their survival to fibronectin by upregulating integrin α5β 1. Most of the FGF-2-arrested cells fail to establish optimal ligation to fibronectin and undergo cell death. Cells that do attach to fibronectin, another major constituent of the bone marrow microenvironment, stay alive and growth-arrested for many weeks. Using function-blocking antibodies and peptides, a specific contribution of α5β1-fibronectin interaction in maintaining survival of growth-arrested cells was demonstrated. The present invention thus allows for methods, agents and pharmaceutical compositions that can be used to potentiate the activity of chemotherapy or radiation therapy.
FILED Wednesday, July 16, 2003
APPL NO 10/521841
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
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US 07749968 Rodriguez et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Ronald Rodriguez (Glenwood, Maryland);  Shawn E. Lupold (Ellicott City, Maryland)
ABSTRACT The invention provides isolated PSMA binding peptides, as well as pharmaceutical compositions thereof. Also provided are diagnostic and therapeutic methods utilizing the PSMA binding peptides, as well as methods for identifying further PSMA binding peptides.
FILED Tuesday, August 05, 2003
APPL NO 10/523498
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/16
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US 07750132 Ulrich
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert G. Ulrich (Frederick, Maryland)
ABSTRACT The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.
FILED Tuesday, January 17, 2006
APPL NO 11/333682
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750133 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Luyuan Li (Pittsburgh, Pennsylvania);  Hongguang Pan (Rockville, Maryland)
ABSTRACT This invention discloses two new VEGI isoforms named VEGI-192a and VEGI-192b consisting of 192 amino acid residues. These isoforms show endothelial cell-specific expression and share a C-terminal 151-residues segment with the previously described VEGI-174 and VEGI-251. Methods of using these isoforms of VEGI in diagnosing, screening agonist and antagonist of the isoforms, and treating various angiogenesis-related diseases are also disclosed.
FILED Thursday, December 06, 2007
APPL NO 11/999918
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.100
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US 07750174 Snow et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Arthur W. Snow (Alexandria, Virginia);  Edward E. Foos (Alexandria, Virginia)
ABSTRACT The compound is a silane surface treatment agent and is useful for modifying the surfaces of silicon oxide and other metal oxides with hexafluorodimethyl carbinol functional groups. Additionally provided is a surface treatment procedure that effectively bonds it and other alkoxysilanes via homogeneous and heterogeneous amine catalysis onto metal oxide surfaces.
FILED Friday, October 12, 2007
APPL NO 11/907501
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
556/406
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US 07750175 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Qinglan Huang (Libertyville, Illinois)
ABSTRACT New organic light-emitting diodes and related hole transport compounds and methods for fabrication, using siloxane self-assembly techniques.
FILED Tuesday, August 24, 2004
APPL NO 10/924730
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Organic compounds
556/424
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US 07750234 Deng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) The University Of Toledo (Toledo, Ohio)
INVENTOR(S) Xunming Deng (Sylvania, Ohio);  Liwei Xu (Sylvania, Ohio)
ABSTRACT An integrated photoelectrochemical (PEC) cell generates hydrogen and oxygen from water while being illuminated with radiation. The PEC cell employs a liquid electrolyte, a multi-junction photovoltaic electrode, and a thin ion-exchange membrane. A PEC system and a method of making such PEC cell and PEC system are also disclosed.
FILED Monday, May 23, 2005
APPL NO 11/134929
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/252
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US 07750294 Bright et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Frank V. Bright (Williamsville, New York);  William G. Holthoff (Tonawanda, New York);  Elizabeth C. Tehan (Buffalo, New York)
ABSTRACT A photonic sensor system is provided. The system generally includes a beta emission source, optionally, a scintillation layer, and a luminophore-containing sensory layer. The system can be embodied in a particle. Also provided are photonic sensor strategies which are highly accurate and photonic sensors which are highly stable.
FILED Thursday, March 10, 2005
APPL NO 11/076729
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/308
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US 07750370 Smorchkova et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Northrop Grumman Space and Mission Systems Corp. (Los Angeles, California)
INVENTOR(S) Ioulia Smorchkova (Lakewood, California);  Robert Coffie (Camarillo, California);  Ben Heying (Fullerton, California);  Carol Namba (Walnut, California);  Po-Hsin Liu (Anaheim, California);  Boris Hikin (Los Angeles, California)
ABSTRACT A semiconductor device is fabricated to include source and drain contacts including an ohmic metal sunken into the barrier layer and a portion of the channel layer; a protective dielectric layer disposed between the source and drain contacts on the barrier layer; a metallization layer disposed in drain and source ohmic vias between the source contact and the protective dielectric layer and between the protective dielectric layer and the drain contact; and a metal T-gate disposed above the barrier layer including a field mitigating plate disposed on a side portion of a stem of the metal T-gate.
FILED Thursday, December 20, 2007
APPL NO 12/003098
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/194
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US 07750462 Cohn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Microassembly Technologies, Inc. (Richmond, California)
INVENTOR(S) Michael Bennett Cohn (Berkeley, California);  Joseph T. Kung (Santa Clara, California)
ABSTRACT Improved microelectromechanical systems (MEMS), processes and apparatus using thermocompression bonding are disclosed. For example, process embodiments are disclosed in which wafer-scale as well as die-scale thermocompression bonding is utilized to encapsulate MEMS and/or to provide electrical interconnections with MEMS. Apparatus embodiments include apparatus for performing thermocompression bonding and bonded hybrid structures manufactured in accordance with the process embodiments. Devices having various substrate bonding and/or sealing configurations variously offer the advantage of reduced size, higher manufacturing yields, reduced costs, improved reliability, improved compatibility with existing semiconductor manufacturing process and/or greater versatility of applications.
FILED Tuesday, October 30, 2007
APPL NO 11/929115
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/704
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US 07750535 Kubena et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Randall L. Kubena (Oak Park, California);  David T. Chang (Calabasas, California);  Jinsoo Kim (Avondale, Pennsylvania)
ABSTRACT A method for fabricating a quartz nanoresonator which can be integrated on a substrate, along with other electronics is disclosed. In this method a quartz substrate is bonded to a base substrate. The quartz substrate is metallized so that a bias voltage is applied to the resonator, thereby causing the quartz substrate to resonate at resonant frequency greater than 100 MHz. The quartz substrate can then be used to drive other electrical elements with a frequency equal to its resonant frequency. The quartz substrate also contains tuning pads to adjust the resonant frequency of the resonator. Additionally, a method for accurately thinning a quartz substrate of the resonator is provided. The method allows the thickness of the quartz substrate to be monitored while the quartz substrate is simultaneously thinned.
FILED Friday, May 04, 2007
APPL NO 11/800294
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/320
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US 07750538 Goat et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Delphi Technologies Holding S.arl (Troy, Michigan)
INVENTOR(S) Christopher Andrew Goat (Offham, United Kingdom);  Martin Paul Hardy (Gillingham, United Kingdom)
ABSTRACT A piezoelectric actuator for use in a fuel injection system of an internal combustion engine, the actuator comprising a stack of ferroelectric layers; an encapsulation for protecting the stack from the ingress of liquid; and oxygenation means for providing oxygen to the ferroelectric layers, the means positioned between the encapsulation and stack. The oxygenation means is preferably impregnated in a fabric which forms a layer between the encapsulation and the stack.
FILED Friday, November 24, 2006
APPL NO 12/085243
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/344
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US 07750664 Kirichenko
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Hypres, Inc (Elmsford, New York)
INVENTOR(S) Alexander F. Kirichenko (Pleasantville, New York)
ABSTRACT A programmable phase shifter is constructed of Rapid Single Flux Quantum (RSFQ) logic elements. The logic elements may include an RSFQ inverter and an RSFQ T flip-flop. A digital word comprising N bits is used to control the amount of phase shift and the phase shifter selectively imparts a respective phase shift for any of 2N states that can be represented by the digital word. The RSFQ logic elements utilize Josephson junctions which operate in the superconducting temperature domain.
FILED Friday, March 13, 2009
APPL NO 12/403537
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Electronic digital logic circuitry
326/3
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US 07750709 Schauer et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Oracle America, Inc. (Redwood Shores, California)
INVENTOR(S) Justin M. Schauer (San Francisco, California);  Robert D. Hopkins (Hayward, California)
ABSTRACT One embodiment of the present invention provides a system that biases a floating node within an integrated circuit. During operation, the system first identifies the floating node within the integrated circuit to be biased. The system then determines a desired bias voltage. Next, the system couples a low-power bias source to the floating node to supply the desired bias voltage, wherein the floating node is biased without stopping data transmission through the floating node during biasing.
FILED Friday, January 05, 2007
APPL NO 11/651221
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Miscellaneous active electrical nonlinear devices, circuits, and systems
327/264
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US 07750752 Kosinski
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John A. Kosinski (Neptune, New Jersey)
ABSTRACT Programmable SAW filter module are provided to overcome undesirable drawbacks, limitations and shortcomings associated with “in-line” SAW filters, such as insertion loss, propagation loss and strong signal capture effects. The programmable SAW filter modules remove the SAW structure from the primary signal path, adding signal gain to drive the splitter and using the SAW portion of the circuit as a programmable impedance element. The programmable SAW filter module includes an amplifier, an impedance, a surface acoustic wave propagation element, a splitter, input and output IDT electrodes, input and output interdigitated transducers, means for gain control and a combiner to combine or sum the signals received from the output IDT electrodes and form an output signal. The input and output IDT's are fully integrated circuits comprising the power splitter and power combiner functions, the phase shift, and gain functions. The embodiments include an amplifier and impedance preceding the input splitter, the amplifier preceding the input splitter with the impedance connected to the combiner, and placing programmable SAW devices in both branches of the circuit.
FILED Wednesday, June 13, 2007
APPL NO 11/818455
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/17.100
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US 07750853 Cirineo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Anthony Cirineo (Ventura, California);  Albert F. Davis (Ventura, California);  Marvin L. Ryken (Oxnard, California)
ABSTRACT A partially shorted microstrip antenna configured to wrap around a projectile's body without interfering with the aerodynamic design of the projectile. The microstrip antenna has three identical conformal antenna elements equally spaced around the circumference of the projectile's body. The antenna has an operating frequency of 231.0 MHz±400 KHz. Each antenna element includes a plurality of vias which operate as a partial short connecting the radiating element to the ground plane and thereby increase the bandwidth of the antenna element.
FILED Tuesday, July 29, 2008
APPL NO 12/181421
ART UNIT 2821 — Semiconductors/Memory
CURRENT CPC
Communications: Radio wave antennas
343/700.MS0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750869 Mosallaei
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Hossein Mosallaei (Brookline, Massachusetts)
ABSTRACT RF-optical metamaterials with (±∈, ±μ) figures-of-merit of interest are constructed from coupled magnetic and dielectric multi-resonant multi-disks (finite-size cylinders) or multi-sphere lattices arranged in a periodic or a random fashion to offer tailored magnetic and electric dipole moments. The present metamaterials include embedded particles arrays that provide coupled magnetic and electronic modes equivalent to L (inductor) and C (capacitor) circuit models. Novel arrangements of these dipole modes (L and C) tailor the transfer function to the physics of interest.
FILED Thursday, July 24, 2008
APPL NO 12/220438
ART UNIT 2821 — Semiconductors/Memory
CURRENT CPC
Communications: Radio wave antennas
343/911.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750962 Anthony
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Michael P. Anthony (Andover, Massachusetts)
ABSTRACT The present invention provides an apparatus for adding or subtracting an amount charge to or from a charge packet in a CCD as the packet traverses the CCD. The apparatus uses a “wire transfer” device structure to perform the addition or subtraction of charge during the charge packets traversal across the device. A pair of electrically interconnected diffusions are incorporated within the charge couple path to provide an amount of charge which can be added or subtracted from packets as the packets traverse the CCD.
FILED Tuesday, February 20, 2007
APPL NO 11/676640
ART UNIT 2622 — Selective Visual Display Systems
CURRENT CPC
Television
348/311
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US 07751109 Hoffman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Robert C. Hoffman (Woodstock, Virginia);  Timothy Pritchett (Silver Spring, Maryland)
ABSTRACT Various embodiments of an improved electro-optic shutter are disclosed. One embodiment comprises an electro-optic element, first and second polarizers, and a pair of electrodes. The electro-optic element has opposing transverse surfaces and operates as a half wave plate when a voltage Vπ is applied to the element. The first and second polarizers are each disposed adjacent to one transverse surface of the electro-optic element. The first and second electro-optic element have parallel transmission axes. Each electrode is disposed on one of the transverse surfaces of the electro-optic element and has an electric field which is substantially uniform over the transverse extent of the electro-optic element.
FILED Thursday, September 14, 2006
APPL NO 11/527649
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/257
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US 07751118 Di Teodoro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Fabio Di Teodoro (Everett, Washington);  Christopher D. Brooks (Kenmore, Washington)
ABSTRACT A method and apparatus use a photonic-crystal fiber having a very large core while maintaining a single transverse mode. In some fiber lasers and amplifiers having large cores problems exist related to energy being generated at multiple-modes (i.e., polygamy), and of mode hopping (i.e., promiscuity) due to limited control of energy levels and fluctuations. The problems of multiple-modes and mode hopping result from the use of large-diameter waveguides, and are addressed by the invention. This is especially true in lasers using large amounts of energy (i.e., lasers in the one-megawatt or more range). By using multiple small waveguides in parallel, large amounts of energy can be passed through a laser, but with better control such that the aforementioned problems can be reduced. An additional advantage is that the polarization of the light can be maintained better than by using a single fiber core.
FILED Sunday, May 28, 2006
APPL NO 11/420754
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optical: Systems and elements
359/333
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US 07751171 Carnahan
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) NanoLab, Inc. (Newton, Massachusetts)
INVENTOR(S) David L. Carnahan (Needham, Massachusetts)
ABSTRACT A nanoscale grasping device comprising at least three electrostatically actuated grasping elements, wherein the nanoscale grasping device may be used to more accurately grasp an object, more easily hold an object in a defined location or orientation and more readily manipulate an object.
FILED Monday, September 12, 2005
APPL NO 11/224684
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/233
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US 07751212 Perkinson
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Joseph C. Perkinson (Nashua, New Hampshire)
ABSTRACT Methods and apparatus to provide a rectifier having a high power factor not limited by voltage ratings of switching devices. Methods and apparatus can include pairs of series-coupled switches coupled to a respective phase signal to, along with respective diode pairs, apportion voltage over a series of load capacitors coupled across the rectifier DC output terminals.
FILED Monday, April 23, 2007
APPL NO 11/738660
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electric power conversion systems
363/127
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US 07751460 Vetrovec et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Jan Vetrovec (Larkspur, Colorado);  Charles C. Thompson (Moorpark, California);  Tri H. Tran (Arcadia, California)
ABSTRACT A solid state laser system having at least one gas injector is disclosed. The gas injector may be configured to so as cause gas flow in a path of the laser beam in order to mitigate distortion of the laser beam due to optical path difference. Each gas injector may be configured so as to cause gas flow proximate at least one optical surface of a solid state gain element of the laser beam system. In this manner gain uniformity may be enhanced so as to facilitate use of the laser system in a variety of military and commercial applications.
FILED Monday, April 17, 2006
APPL NO 11/405281
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/55
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US 07751462 Nettleton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John E. Nettleton (Fairfax Station, Virginia);  Bradley W. Schilling (Fredericksburg, Virginia)
ABSTRACT A YAG/Nd:YAG block where an Nd:YAG block ends in a peak integrated inside a YAG block. The YAG block has reflective surfaces positioned at 45° to one another. The angled reflective surfaces serve as a “mirror” within the laser cavity to effectively increase the length of the cavity by a factor greater than 2. Fused to the output end of the laser cavity are a polarizer, an active/passive Q-switch, a one quarter waveplate and an output coupler. In operation, the laser cavity is pumped either from the side or the end of the cavity. The optical components of the present invention are bonded to form one optical ‘block’. All the components are prealigned during the crystal manufacturing process to form the optical laser cavity. The width of the cavity should be selected such that nearly all of the laser diode pump output is absorbed by the cavity.
FILED Wednesday, March 14, 2007
APPL NO 11/686329
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/107
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US 07751469 Eldar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yonina C. Eldar (Cambridge, Massachusetts);  Alan V. Oppenheim (Lexington, Massachusetts)
ABSTRACT The present invention is directed toward an apparatus and method for receiving signals, demodulating the signals and shaping the correlation of the output of a correlation demodulator. The present invention can be used irrespective of whether the received signals have noise components that are Gaussian or non-Gaussian. Moreover, the present invention can be utilized when a predetermined set of received signals is linearly independent or linearly dependent.
FILED Tuesday, February 20, 2001
APPL NO 09/788890
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/152
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US 07751645 Reneker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S)
ASSIGNEE(S) Goodrich Corporation (Charlotte, North Carolina)
INVENTOR(S) Douglas Alan Reneker (Naperville, Illinois);  Christopher Cotton (Honeoye Falls, New York);  Damon Diehl (Rochester, New York)
ABSTRACT A camera for aerial photography includes a reference projector that projects collimated beams of light into the optical system entrance aperture which are imaged by an image recording device. The beams produce fiducial images present in every image captured by the imaging recording device. The fiducial images can be used to characterize the performance of the optical system and derive distortion correction coefficients. The distortion correction coefficients can be applied to a portion of an image, such as a group of pixels, or to the entire image, to thereby compensate for distortions in the optical system. In some embodiments, e.g., airborne cameras, the projector is rigidly coupled to an inertial measurement unit. The ability of the airborne camera to perform object geolocation from imagery is improved. The fiducial images enable optical system performance to be characterized and distortion correction coefficients to be obtained and thereby improve the accuracy of a ray angle calculation to the object of interest. Furthermore, the ray angle can be related to an inertial measurement system coordinate system using a direction cosine matrix.
FILED Friday, December 05, 2008
APPL NO 12/315806
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/275
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US 07751654 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Michal Lipson (Ithaca, New York);  Bradley Schmidt (Ithaca, New York);  Sameer Pradhan (Portland, Oregon);  Qianfan Xu (Ithaca, New York)
ABSTRACT A silicon electro-optic waveguide modulator is formed using a metal-oxide-semiconductor (MOS) configuration. Various embodiments are described using different modes of operation of the MOS diode and gate oxide thicknesses. In one example, a high-speed submicron waveguide active device is formed using silicon-on-insulator. A micro-ring resonator intensity-modulator exhibits switching times on the order of tens of pS with modulation depth of 73% with a bias voltage of 5 volts.
FILED Friday, March 03, 2006
APPL NO 11/367756
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/1
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US 07751977 Winkler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Michael F. Winkler (Vicksburg, Mississippi);  W. Scott Noble (Franklin, Tennessee)
ABSTRACT COTS devices are integrated into a system employing custom software and custom hardware and software interfaces to collect and communicate data concerning current flows around fixed structure (e.g., inland locks, bridges, harbor structures, etc.) in various bodies of water (e.g., inland waterways, harbors, canals, etc.). Embodiments comprise: sensors and communications equipment, for example wireless systems that transmit sensor data to a lock house; lock house communications equipment that receive sensor data; a processor, e.g., a personal computer, with installed custom software and interface for processing data; an Automatic Identification System (AIS) transponder interfaced to the processor; an AIS installed in vessels to include an electronic vector chart display, such as may be installed in a towboat pilothouse; and an optional web-based database application for lock operators to record dam operation scenarios that may be used in research, investigations, and the like.
FILED Tuesday, July 10, 2007
APPL NO 11/822756
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/3
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US 07751999 McAtee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert F. McAtee (Bloomington, Indiana);  Michael A. Eagan (Washington, Indiana);  Eric Wallis (Bloomington, Indiana);  Norman Popkie, Jr. (Rock Hill, South Carolina);  Matthew Todd Griffin (Fort Mill, South Carolina)
ABSTRACT The present invention can be generally described as a vapor detection instrument testing system and testing process. This testing system integrates a computing system loaded with testing software, and a test-substance generating device. The present device is portable and provides a user with the ability to perform vapor detection instrument testing at the field side of the vapor detection instrument. The portability of the vapor detection instrument testing system results in more frequent instrument testing and less detection instrument down time.
FILED Wednesday, March 19, 2008
APPL NO 12/076540
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/85
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US 07752027 Cutts et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Norwich University Applied Research Institutes (Northfield, Vermont)
INVENTOR(S) Andrew Cutts (New London, New Hampshire);  Robert Schmidt (Chicago, Illinois)
ABSTRACT Methods and apparatus for simulating a distributed business process are disclosed. The methods and apparatus simulate an interdependent business process, such as a financial transaction system, in a secure distributed manner. Each business entity that is part of the interdependent business process models itself on a local client device at any chosen level of detail. A simulation server connects the separate client based simulations into one large simulation. Details of each local simulation may be hidden from other simulation participants. However, interruptions in business flow caused by simulated disruptions introduced at the simulation server and/or a client device are propagated to all of the effected simulation participants via the simulation server. In addition, if a client based model is not available, the server supplies a software agent to replace the inputs and outputs normally associated with that portion of the overall simulation.
FILED Friday, November 03, 2006
APPL NO 11/556462
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/22
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US 07752089 Sarangapani et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Jagannathan Sarangapani (Rolla, Missouri);  Anil Ramachandran (Rolla, Missouri);  Can Saygin (San Antonio, Texas);  Kainan Cha (Olathe, Missouri)
ABSTRACT An adaptive inventory management system and method eliminates or minimizes frequency interference issues within a facility that employs a plurality of RFID readers for purposes of tracking and managing inventory. A middleware server activates and deactivates adjacent RFID readers within the facility based on the location of an item having an RFID tag. The middleware server also queries an inventory database based on the information collected from the RFID tag of the item and generates a command signal based on information retrieved from the database to control the travel route of the vehicle transporting items of inventory within the facility.
FILED Tuesday, February 26, 2008
APPL NO 12/037799
ART UNIT 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/28
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US 07752369 Kailas et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Krishnan Kunjunny Kailas (Tarrytown, New York);  Brian Chan Monwai (Austin, Texas);  Viresh Paruthi (Austin, Texas)
ABSTRACT A system for formal verification of bounded fairness properties of pseudo random number generators and arbiters that use random priority-based arbitration schemes. The formal verification system determines an upper bound of a request-to-grant delay of an arbiter in terms of a number of complete random sequences. The formal verification system also determines, in terms of a number of clock cycles, an upper bound and a lower bound of a length of a complete random sequence in the random number sequence generated by a random number generator used by the arbiter. The formal verification system then determines a worst case request-to-grant delay bounds of the arbiter system, in terms of a number of clock cycles, by combining the upper bound of the request-to-grant delay of the arbiter with the upper bound of the length of the complete random sequence and the lower bound of the length of the complete random sequence.
FILED Friday, May 09, 2008
APPL NO 12/118211
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital data processing systems: Input/output
710/244
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752417 Manczak et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Oracle America, Inc. (Redwood City, California)
INVENTOR(S) Olaf Manczak (Hayward, California);  Christopher A. Vick (San Jose, California);  Michael H. Paleczny (San Jose, California);  Jay R. Freeman (Palo Alto, California);  Phyllis E. Gustafson (Pleasanton, California)
ABSTRACT A computer system may be configured to dynamically select a memory virtualization and corresponding virtual-to-physical address translation technique during execution of an application and to dynamically employ the selected technique in place of a current technique without re-initializing the application. The computer system may be configured to determine that a current address translation technique incurs a high overhead for the application's current workload and may be configured to select a different technique dependent on various performance criteria and/or a user policy. Dynamically employing the selected technique may include reorganizing a memory, reorganizing a translation table, allocating a different block of memory to the application, changing a page or segment size, or moving to or from a page-based, segment-based, or function-based address translation technique. A selected translation technique may be dynamically employed for the application independent of a translation technique employed for a different application.
FILED Monday, June 05, 2006
APPL NO 11/447189
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/209
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752459 Cowan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Novell, Inc. (Provo, Utah)
INVENTOR(S) Stanley Crispin Cowan (Portland, Oregon);  Seth Richard Arnold (Lake Owego, Oregon);  Steven Michael Beattie (Portland, Oregon);  Perry Michael Wagle (Hillsboro, Oregon)
ABSTRACT To protect computer programs against security attacks that attempt to corrupt pointers within the address space of the program, the value of a pointer is encrypted each time the pointer is initialized or modified, and then the value is decrypted before use, i.e., each time the pointer is read. Preferably, the encrypting and decrypting steps are effected by instructions generated by a compiler during compilation of the program. One convenient method of implementing the encrypting and decrypting steps is by XOR'ing the pointer with a predetermined encryption key value, which could be specially selected or selected at random.
FILED Friday, December 06, 2002
APPL NO 10/313940
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Support
713/190
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752483 Muresan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
United States Special Operations Command (SOCOM)
APPLICANT(S)
ASSIGNEE(S) Science Applications International Corporation (San Diego, California)
INVENTOR(S) David Darian Muresan (Arlington, Virginia);  Andrew Charles Weitz (Redlands, California)
ABSTRACT A Heart Beat System (HBS) enables both inertial navigation system (INS) technology and other sensors, e.g., laser radar (LIDAR) systems, cameras and the like to be precisely time-coupled. The result of this coupling enables microsecond control by the HBS to each sensor slave component. This synchronization enables the precise time of each sensor measurement to be known which in turn allows highly accurate world coordinates to be computed from each set of received date, e.g., laser pulses range data. Such precision results in 3-dimensional point cloud data with relative accuracies in the 5-10 cm range and absolute positioning accuracies in the sub 40 cm range. This precision further enables multiple sensors to be used simultaneously with outstanding registration which leads to fused 3D point cloud databases representing a more comprehensive urban scene. Finally, 3D data collected from subsequent missions can be used for precision change detection analysis.
FILED Wednesday, December 13, 2006
APPL NO 11/637783
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Support
713/601
VIEW PATENT @ USPTO:  Full Text   PDF 
US D619044 Kiel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Thomas J. Kiel (Bernardsville, New Jersey);  Edward Zuckerman (Denville, New Jersey);  Sanjay Parimi (Chester, New Jersey);  Allen Brokaw (Trenton, New Jersey)
ABSTRACT
FILED Wednesday, October 14, 2009
APPL NO 29/345320
ART UNIT 2914 — Design
CURRENT CPC
Transportation
D12/12
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07749490 Sommer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Jurg M. Sommer (Orinda, California);  Raymond A. Chavez (Alameda, California);  Kirk W. Johnson (Moraga, California);  Linda May Rothblum Watkins (Boulder, Colorado)
ABSTRACT IL-10 sequence variants are disclosed that retain the therapeutically desirable anti-inflammatory properties of wild-type IL-10 but do not retain the hemoatopoeitic cell regulatory and cell proliferative activities. The mutant IL-10 polypeptides of the invention are used in methods of treating diseases involving inflammatory response, including neuropathic pain and other neurological disorders.
FILED Friday, May 26, 2006
APPL NO 11/920711
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/85.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749491 Engelhardt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa);  Targeted Genetics Corporation (Seattle, Washington)
INVENTOR(S) John F. Engelhardt (Iowa City, Iowa);  Keith L. Munson (Seattle, Washington);  Ziying Yan (Iowa City, Iowa)
ABSTRACT Agents and methods to alter rAAV transduction are provided.
FILED Wednesday, March 31, 2004
APPL NO 10/815262
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749503 Tobia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Dynamis Therapeutics, Inc. (Elkins Park, Pennsylvania)
INVENTOR(S) Annette Tobia (Wyndmoor, Pennsylvania);  Francis Kappler (Philadelphia, Pennsylvania)
ABSTRACT The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.
FILED Friday, June 15, 2007
APPL NO 11/818997
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/146.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749510 Portnoy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Daniel A. Portnoy (Albany, California);  Richard Lane Calendar (Berkeley, California);  Peter M. Lauer (Oakland, California)
ABSTRACT Site-specific Listeria integration vectors and methods for their use are provided. The subject vectors include a bacteriophage integrase gene and a bacteriophage attachment site, where in many embodiments the bacteriophage that is the source of these elements is a listeriophage. In certain embodiments, the subject vectors further include a multiple cloning site, where the multiple cloning site may further include a polypeptide coding sequence, e.g., for a heterologous antigen. The subject vectors and methods find use in a variety of different applications, including the study of Listeria species and the preparation of Listeria vaccines.
FILED Tuesday, April 29, 2003
APPL NO 10/547999
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/234.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749517 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John A. Young (San Diego, California);  Heather M. Scobie (San Diego, California);  G. Jonah A. Rainey (San Diego, California);  Kenneth A. Bradley (Santa Monica, California)
ABSTRACT The present invention provides compositions useful in preparing and/or serving as antitoxins against Bacillus anthracis, the causative agent of anthrax. The present invention also provides polypeptides and polynucleotides relating to the capillary morphogenisis gene 2 (CMG-2), vectors containing the polynucleotides and polypeptides, and host cells containing related polynucleotide molecules, all used in association with the treatment of, or the research and development of treatments for anthrax. The present invention also relates to methods for identifying molecules that bind CMG-2 and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.
FILED Thursday, January 26, 2006
APPL NO 11/340424
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/246.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749585 Zamore
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Alan Zamore (Chestnut Ridge, New York)
ABSTRACT Medical dilatation balloons comprise a polymer that has the attribute of memory, and/or is crosslinked to impart memory. Such balloons exhibit a reduced tendency to overinflate at high inflation pressures. Furthermore, such balloons when shrunk radially by the application of heat while restraining axial shrinkage, exhibit customizable linear or non-linear compliance curves and lower crosslinking profile relative to the same balloon when unshrunk. Also disclosed is an expansive element within a tube whose outer diameter is equal to the outer diameter of the tube from which it was made. In addition, disclosed are (a) processes for preparing crosslinkable polymers, (b) joining crosslinked balloons to catheter systems, (c) forming shrunk balloon elements, and (d) forming an expansive element within a tube whose outer diameter is equal to the outer diameter of the tube from which it was made.
FILED Friday, October 17, 2003
APPL NO 10/688292
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/35.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749694 Ghosh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Partho Ghosh (San Diego, California);  Stephen McMahon (Renfrew, United Kingdom);  Jason Miller (Carlsbad, California);  Jeffrey Lawton (San Diego, California)
ABSTRACT This invention provides a class of binding proteins with a range of binding specificities and affinities based upon variation at select amino acid positions within a scaffold. The variable positions may be readily modified to produce a library of binding proteins with different binding specificities and affinities. The library may be screened to identify one or more as binding a ligand of interest. Compositions comprising the binding proteins, as well as methods of using the binding proteins are also provided.
FILED Friday, December 31, 2004
APPL NO 11/027323
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749699 Kool
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Eric T. Kool (Stanford, California)
ABSTRACT Novel compounds having a fluorescence quencher as a leaving group are disclosed. Nucleic acids and other molecules containing a fluorophore and a fluorescence quencher are disclosed as an embodiment of this invention. The use of the oligonucleotides in enzyme-free oligonucleotide ligation reactions results in an increase in fluorescence when the oligonucleotide also contains a nearby fluorophore. The ligation reactions can be performed in solution, on surfaces, or in cells.
FILED Thursday, July 17, 2003
APPL NO 10/604400
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749700 Baird et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Alison E. Baird (Brooklyn, New York);  David F. Moore (Rockville, Maryland);  Ehud Goldin (Rockville, Maryland)
ABSTRACT Methods are provided for evaluating a stroke, for example for determining whether a subject has had an ischemic stroke, determining the severity or likely neurological recovery of a subject who has had an ischemic stroke, and determining a treatment regimen for a subject who has had an ischemic stroke, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes screening for expression in ischemic stroke related genes (or proteins), such as white blood cell activation and differentiation genes (or proteins), genes (or proteins) related to hypoxia, genes (or proteins) involved in vascular repair, and genes (or proteins) related to a specific peripheral blood mononuclear cell (PBMC) response to the altered cerebral microenvironment. Also provided are methods of identifying one or more agents that alter the activity (such as the expression) of an ischemic stroke-related molecule.
FILED Friday, June 17, 2005
APPL NO 11/155835
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749704 Ansell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Stephen M. Ansell (Rochester, Minnesota);  Anne J. Novak (Oronoco, Minnesota)
ABSTRACT The present invention provides an isolated polynucleotide comprising at least one polymorphic nucleotide sequence, for example, at position −871 from the promoter region of the BLyS gene, and diagnostic assays for detecting the presence of this polymorphism associated with a condition associated with BLyS activity, such as hematological malignancy including B cell malignancies. The diagnostic assays are useful in predicting an individual's likelihood of developing a condition associated with BLyS activity, such as hematological malignancies, and for methods for treating an individual clinically diagnosed with a condition associated with BLyS activity, such as prediction of a patient's likelihood to respond to a specific drug treatment. The invention also provides an array of nucleic acid molecules immobilized on a solid surface, where at least one of the nucleic acid molecules comprises a BLyS polymorphic nucleic acid molecule. The nucleic acid arrays of the invention allow rapid detection of hybridizing nucleic acid-molecules, in a nucleic acid sample from an individual, of a BLyS polymorphism associated with hematological malignancy.
FILED Wednesday, November 01, 2006
APPL NO 11/555559
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749706 Bacher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Promega Corporation (Madison, Wisconsin)
INVENTOR(S) Jeffrey W. Bacher (Madison, Wisconsin);  Laura Flanagan (Fort Atkinson, Wisconsin);  Nadine Nassif (Madison, Wisconsin)
ABSTRACT Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits of the present invention can be used to detect or diagnose diseases associated with microsatellite instability, such as certain types of cancer.
FILED Tuesday, December 19, 2006
APPL NO 11/612567
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749709 Herman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University School of Medicine (Baltimore, Maryland)
INVENTOR(S) James G. Herman (Lutherville, Maryland);  Hirohide Yoshikawa (Tokyo, Japan);  Curtis C. Harris (Garrett Park, Maryland)
ABSTRACT Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addition, methods of treating a cancer patient, wherein cancer cells in the patient exhibit methylation-silenced transcription of SOCS/CIS gene such as a SOCS-1 gene, are provided, as are reagents for practicing such methods.
FILED Friday, February 22, 2008
APPL NO 12/036182
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749715 Russo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S) Giandomenico Russo (Rome, Italy);  Carlo M. Croce (Philadelphia, Pennsylvania)
ABSTRACT The present invention relates to nucleotide sequences of TCL-1 genes and amino acid sequences of their encoded proteins, as well as derivatives and analogs thereof, and antibodies thereto. The TCL-1 gene sequence is preferentially expressed early in T and B lymphocyte differentiation. The present invention further relates to the use of TCL-1 genes and their encoded proteins as diagnostic and therapeutic reagents for the detection and treatment of disease states associated with chromosomal abnormalities.
FILED Tuesday, April 25, 2006
APPL NO 11/412216
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749719 Kawakami et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Yutaka Kawakami (Kanagawa, Japan);  Steven A. Rosenberg (Potomac, Maryland)
ABSTRACT The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the MART-1 melanoma antigen and a second melanoma antigen designated gp100. This invention further provides immunogenic peptides derived from the MART-1 melanoma antigen or gp100 antigen which have been modified to enhance their immunogenicity. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma.
FILED Wednesday, October 31, 2007
APPL NO 11/932406
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749720 Olefsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jerrold M. Olefsky (Solana Beach, California);  Isao Usui (Toyama, Japan);  Takeshi Imamura (San Diego, California)
ABSTRACT The invention herein provides a mode of treating metabolic syndrome, which includes Type 2 diabetes mellitus and insulin resistance in human and other subjects by identifying and administering an insulin sensitizing compound which modulates GRK2 function in the insulin signaling pathway. The invention also provides polynucleotides, polypeptides, vectors, cells, tissues and organisms useful in the identification and treatment of metabolic syndrome. A number of desirable insulin sensitizing aspects are achieved by various embodiments of the present invention.
FILED Friday, June 17, 2005
APPL NO 11/570864
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749725 Rohrwasser et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Andreas Rohrwasser (Salt Lake City, Utah);  Terry Morgan (Salt Lake City, Utah);  Jean-Marc Lalouel (Salt Lake City, Utah)
ABSTRACT The present invention relates to a method for screening drugs for use in treating hypertension using the tubular renin-angiotensinogen system identified by the present invention. The invention further relates to a method to diagnose sodium status and sensitivity in an individual by measuring urinary angiotensinogen or angiotensin-I.
FILED Wednesday, October 16, 2002
APPL NO 10/271661
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/23
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749726 Chuck
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Roy S. Chuck (Towson, Maryland)
ABSTRACT Methods and systems for a) identifying and isolating stem cells, b) assessing mitochondrial distribution and structure in living cells and c) performing fluorescence microscopy on living cells while the cells remain within a condition-controlled cell culture chamber.
FILED Tuesday, November 08, 2005
APPL NO 11/667280
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/29
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749729 Heinecke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Jay W. Heinecke (Seattle, Washington);  John F. Oram (Seattle, Washington)
ABSTRACT The present invention relates to diagnostic tests, methods and kits that are useful to assess a subject's risk of developing a pathologic condition related in part to the presence of HDL oxidation product. Measuring the quantity of one or more HDL oxidation products present in the blood is useful in evaluating risk for developing or evaluating the severity of a disease or evaluating response to treatment for such a disease as, for instance, cardiovascular disease.
FILED Tuesday, July 19, 2005
APPL NO 11/572308
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749752 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S) Si-Yi Chen (Pearland, Texas);  Zhaoyang You (Houston, Texas)
ABSTRACT This invention relates to an expression vector wherein said expression vector comprises a polynucleotide promoter sequence, a polynucleotide encoding a signal sequence, a polynucleotide encoding an antigen protein or peptide, a polynucleotide encoding a cell binding element, and a polynucleotide polyadenylation sequence all operatively linked. More particularly, it relates to the method of eliciting an immune response directed against an antigen in a mammal comprising the steps of introducing the expression vector into a cell, expressing the vector to produce an antigen under conditions wherein the antigen is secreted from the cell, endocytosing the secreted antigen into the cell, processing the antigen, and presenting fragments to a receptor to elicit a T-cell response. In addition, this invention relates to a vaccine and a method of use. The invention also relates to the method of identifying MHC-II restricted epitopes.
FILED Friday, August 31, 2007
APPL NO 11/896337
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749769 Hunt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Donald F Hunt (Charlottesville, Virginia);  Joshua J. Coon (Madison, Wisconsin);  John Edward Philip Syka (Charlottesville, Virginia)
ABSTRACT The present invention relates to a new method for identifying polypeptides by deducing the amino acid sequence of the carboxy and amino termini by a mass spectrometer analysis. The method comprises the steps of dissociating highly charged peptide precursor ions (e.g., z>4) using electron transfer dissociation inducing anions followed by removal of those reagents and introduction of a second, proton transfer inducing anion type. The second PTR reaction duration is adjusted to convert the ETD products to primarily the +1 charge-state to reduce the highly charged c and z-type fragments, producing an m/z spectrum containing a series of c and z-type fragment ions that are easily interpreted to reveal the sequence of the amino and carboxy terminus, respectively.
FILED Friday, October 07, 2005
APPL NO 11/664661
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/173
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US 07749958 Schiemann
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) National Jewish Health (Denver, Colorado)
INVENTOR(S) William P. Schiemann (Denver, Colorado)
ABSTRACT Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC homologues that are antagonists or inhibitors of TGF-β and compositions and therapeutic methods using CystC and homologues thereof to regulate the activity of TGF-β, and TGF-β-mediated tumor malignancy and invasion and other TGF-β-mediated fibrotic or proliferative conditions and diseases.
FILED Monday, September 10, 2007
APPL NO 11/852909
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 07749959 Tracey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Feinstein Institute for Medical Research (Manhasset, New York);  The General Hospital Corporation (Boston, Massachusetts);  University of Pittsburgh-of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Kevin J. Tracey (Old Greenwich, Connecticut);  Huan Yang (Douglaston, New York);  Howland Shaw Warren, Jr. (Cambridge, Massachusetts);  Mitchell P. Fink (Pittsburgh, Pennsylvania)
ABSTRACT Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory cytokine cascade in a patient. The compositions comprise a vertebrate HMGB A box, and an antibody preparation that specifically binds to a vertebrate HMGB B box. The methods comprise treating a cell or a patient with sufficient amounts of the composition to inhibit the release of the proinflammatory cytokine, or to inhibit the inflammatory cytokine cascade.
FILED Wednesday, September 19, 2007
APPL NO 11/901880
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 07749967 Hwu et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services. (Washington, District of Columbia)
INVENTOR(S) Patrick Hwu (Houston, Texas);  Rejean LaPointe (Laval, Canada);  Steven A. Rosenberg (Potomac, Maryland);  Maria Parkhurst (Ellicott City, Maryland)
ABSTRACT Immunogenic peptides of a melanoma antigen recognized by T cells, designated gp100, bioassays using the peptides to diagnose, assess or prognose a mammal afflicted with cancer, more specifically melanoma or metastatic melanoma, and use of the proteins and peptides as immunogens to inhibit, prevent or treat melanoma.
FILED Thursday, August 21, 2008
APPL NO 12/195809
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/13
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US 07749971 Bedwell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) David M. Bedwell (Birmingham, Alabama);  Kim M. Keeling (Birmingham, Alabama)
ABSTRACT The present invention provides a method of treating lysosomal storage diseases such as Hurler syndrome and Batten disease in individuals in need of such treatment, comprising the step of administering to said individuals a therapeutically effective dose of an aminoglycoside. In addition, this method may further comprise treating the individual with enzyme replacement therapy. Furthermore, the present invention provides method of pharmacologically suppressing premature stop mutations in an individual with these lysosomal storage diseases, comprising the step of administering to said individual a pharmacologically effective dose of an aminoglycoside.
FILED Wednesday, February 20, 2002
APPL NO 10/079326
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/35
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US 07749976 Dixon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jack E. Dixon (San Diego, California);  David J. Pagliarini (Sommerville, Massachusetts)
ABSTRACT The invention identifies a novel protein tyrosine phosphatase, PTPMT1. The complete nucleic acid and amino acid sequence encoding PTPMT1 is provided. Methods are provided for preventing and/or treating type II diabetes by regulating PTPMT1 levels, which in turn regulates insulin levels.
FILED Wednesday, May 24, 2006
APPL NO 11/440719
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07749984 Wainer et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Irving W. Wainer (Washington, District of Columbia);  Krzysztof Jozwiak (Abingdon, Maryland);  Ruin Moaddel (Germantown, Maryland);  Sarangan Ravichandran (Frederick, Maryland);  Jack R. Collins (Frederick, Maryland)
ABSTRACT A computer readable medium holding data of a molecular model of a ligand-gated ion channel receptor and/or a computer system for modeling said receptor are provided by the instant invention. The molecular model can be used to design novel compounds having activity as non-competitive inhibitors of the ion channel. A preferred embodiment of the invention relates to nicotinic acetylcholine receptors. Compounds having activity as non-competitive inhibitors of ligand-gated ion channel receptors and methods for inhibiting the receptor and treating diseases or disorders mediated by function of the receptor are also disclosed.
FILED Friday, April 09, 2004
APPL NO 10/820809
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/80
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US 07750030 Davis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Michael Davis (Stone Mountain, Georgia);  Kerry J. Ressler (Chamblee, Georgia)
ABSTRACT Methods for treating an individual with a psychiatric order with a pharmacologic agent that enhances learning or conditioning in combination with a session of psychotherapy are provided. These methods of the invention encompass a variety of methods of psychotherapy, and psychodynamically oriented psychotherapy, and psychiatric orders including fear and anxiety disorders, addictive disorders, addictive disorders including substance-abuse disorders, and mood disorders. The pharmacologic agents used for the methods of the present invention are ones that generally enhance learning or conditioning, including those that increase the level of norepinephrine in the brain, those that increase the level of acetylcholine in the brain, and those that enhance N-methyl-D-aspartate (NMDA) receptor transmission in the brain.
FILED Thursday, March 28, 2002
APPL NO 10/473640
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/380
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US 07750050 Schuchman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Mount Sinai School of Medicine of New York University (New York, New York)
INVENTOR(S) Edward H. Schuchman (Haworth, New Jersey);  Robert J. Desnick (New York, New York)
ABSTRACT The present invention provides a method for treating individuals affected with the acid sphingomyelinase-deficient forms of Niemann-Pick disease (i.e., Type A or Type B Niemann-Pick) by administering small molecules as specific molecular “chaperones” for the deficient acid sphingomyelinase (ASM) enzyme associated with the disease. The molecules are ceramide, sphingomyelin, or phosphonucleotide analogues.
FILED Wednesday, November 24, 2004
APPL NO 10/998270
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/625
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US 07750120 Nelsestuen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Saint Paul, Minnesota)
INVENTOR(S) Gary L Nelsestuen (St. Paul, Minnesota)
ABSTRACT The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.
FILED Thursday, November 02, 2006
APPL NO 11/555842
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/384
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US 07750121 Cech et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Geron Corporation (Menlo Park, California);  The Regents of the University of Colorado (Boulder, Colorado)
INVENTOR(S) Thomas R. Cech (Potomac, Maryland);  Joachim Lingner (Epalinges, Switzerland);  Toru Nakamura (San Diego, California);  Karen B. Chapman (Mill Valley, California);  Gregg B. Morin (Oakville, Canada);  Calvin B. Harley (Palo Alto, California);  William H. Andrews (Reno, Nevada)
ABSTRACT The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
FILED Wednesday, August 17, 2005
APPL NO 11/207078
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750123 Marasco et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Dana Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Wayne Marasco (Wellesley, Massachusetts);  Jianhua Sui (Boston, Massachusetts)
ABSTRACT The invention provides scFv antibodies and monoclonal antibodies that neutralize SARS-CoV. Also provided are methods of treating and/or preventing a coronavirus-related disease or disorder such as SARS. The invention also provides methods of vaccinating a patient against SARS-CoV. Also provided are methods of diagnosing coronavirus-related diseases or disorders and methods of detecting the presence of a coronavirus in a sample. The invention additionally provides methods of screening for compounds that modulate the binding of SARS-CoV and the SARS-CoV receptor ACE2 as well as for compounds useful to treat SARS-CoV-related diseases or disorders.
FILED Wednesday, November 24, 2004
APPL NO 10/997201
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750133 Li et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Luyuan Li (Pittsburgh, Pennsylvania);  Hongguang Pan (Rockville, Maryland)
ABSTRACT This invention discloses two new VEGI isoforms named VEGI-192a and VEGI-192b consisting of 192 amino acid residues. These isoforms show endothelial cell-specific expression and share a C-terminal 151-residues segment with the previously described VEGI-174 and VEGI-251. Methods of using these isoforms of VEGI in diagnosing, screening agonist and antagonist of the isoforms, and treating various angiogenesis-related diseases are also disclosed.
FILED Thursday, December 06, 2007
APPL NO 11/999918
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750134 Godzik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S)
ASSIGNEE(S) Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Adam Godzik (San Diego, California);  John C. Reed (Rancho Santa Fe, California)
ABSTRACT The invention provides isolated SUMO-specific protease-like (or “SSP”) domain-containing polypeptides from microorganisms, including bacteria, protozoans and yeast, including Escherichia, Salmonella, Pseudomonas, Chlamydia, Plasmodium, Trypanosma, Mesorhizobium, Rickettsia, Cryptosporidium and Candida species. The invention further provides modifications of such polypeptides, functional fragments therefrom, encoding nucleic acid molecules and specific antibodies. Also provided are methods for identifying polypeptides and compounds that associate with or modulate the activity of the SSP domain-containing polypeptides. Further provided are methods of modulating a biological activity in a cell, and treating pathological conditions, using the described nucleic acid molecules, polypeptides and compounds.
FILED Wednesday, November 20, 2002
APPL NO 10/301533
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750143 Tolentino et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Michael J. Tolentino (Villanova, Pennsylvania);  Samuel Jotham Reich (Bala Cynwyd, Pennsylvania)
ABSTRACT RNA interference using small interfering RNAs which are specific for the vascular endothelial growth factor (VEGF) gene and the VEGF receptor genes Flt-1 and Flk-1/KDR inhibit expression of these genes. Diseases which involve angiogenesis stimulated by overexpression of VEGF, such as diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs.
FILED Thursday, June 08, 2006
APPL NO 11/423006
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750144 Zamore et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Phillip D. Zamore (Northboro, Massachusetts);  György Hutvágner (Worcester, Massachusetts);  Dianne Schwarz (Westborough, Massachusetts);  Martin Simard (Deschambault, Canada)
ABSTRACT The present invention provides methods of enhancing the efficacy and specificity of RNA silencing. The invention also provides compositions for mediating RNA silencing. In particular, the invention provides siRNAs, siRNA-like molecules, shRNAs, vectors and transgenes having improved specificity and efficacy in mediating silencing of a target gene. Therapeutic methods are also featured.
FILED Wednesday, August 04, 2004
APPL NO 10/912440
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/25.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750149 Stahl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Shannon S. Stahl (Madison, Wisconsin);  Christopher C. Scarborough (Madison, Wisconsin)
ABSTRACT Disclosed are carbenes of the general formula:
and including salts thereof, and metal complexes thereof. The carbenes are useful in any reaction where carbenes and carbene-metal complexes are used. The carbenes disclosed herein are particularly useful in asymmetric catalysis.
FILED Monday, April 11, 2005
APPL NO 11/102964
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
540/471
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US 07750537 Hossack et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) John A. Hossack (Charlottesville, Virginia);  Travis N. Blalock (Charlottesville, Virginia);  William F. Walker (Earlysville, Virginia)
ABSTRACT An ultrasound transducer array having a transmit transducer element comprising a transmit transducer material interposed between a transmit electrode and a reference electrode, wherein voltages applied across the transmit electrode and reference electrode induce an acoustic wave to emanate from the transmit transducer material; and a plurality of receive transducer elements positioned in an array on the transmit transducer element, each of the plurality of the receive transducer elements comprising a receive electrode and a receive transducer material interposed between the receive electrode and the reference electrode, and wherein acoustic waves applied to the plurality of receive transducer elements induces receive voltage signals on the receive electrodes with respect to the reference electrode.
FILED Thursday, August 16, 2007
APPL NO 11/840079
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/334
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750632 Qian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Yongxian Qian (Pittsburgh, Pennsylvania);  Fernando E. Boada (Wexford, Pennsylvania)
ABSTRACT A method for producing a magnetic resonance image using an ultra-short echo time. The method includes applying a pulse sequence to an object, detecting a spirally encoded and phase encoded magnetic resonance signal associated with the object, and reconstructing the magnetic resonance image based on the spirally encoded and phase encoded magnetic resonance signal. The pulse sequence includes a slab-selective radiofrequency pulse, a slab-selective gradient pulse, a plurality of variable duration slice encoding gradient pulses, a plurality of first spiral encoding gradient pulses, and a plurality of second spiral encoding gradient pulses. The detection of the spirally encoded and phase encoded magnetic resonance signal occurs concurrently with the application of one of the plurality of first spiral encoding gradient pulses and with the application of one of the plurality of second spiral encoding gradient pulses.
FILED Monday, March 24, 2008
APPL NO 12/054052
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/307
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751039 Ramanujam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Nirmala Ramanujam (Chapel Hill, North Carolina);  Lee G. Wilke (Chapel Hill, North Carolina)
ABSTRACT The subject matter described herein includes an optical assay system for intraoperative assessment of tumor margins. According to one aspect, the subject matter described herein includes a biological sample containment and illumination apparatus for holding a biological sample for illumination by a plurality of electromagnetic radiation probes. The biological sample containment and illumination apparatus includes a plurality of frame members positioned with respect to each other to form an interior space for receiving a biological sample. At least one of the plurality of frame members includes a plurality of probe receiving locations for receiving a plurality of electromagnetic radiation probes. The probe receiving locations position the probes with respect to the biological sample to allow illumination of plural locations of the biological sample by the probes.
FILED Thursday, March 29, 2007
APPL NO 11/729967
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/244
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751057 Oldenburg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Amy L. Oldenburg (Urbana, Illinois);  Stephen A. Boppart (Champaign, Illinois);  Vasilica Crecea (Urbana, Illinois);  Xing Liang (Urbana, Illinois)
ABSTRACT A spectral-domain magnetomotive optical coherence tomography apparatus, includes (a) a spectral-domain optical coherence tomography device, and (b) a magnet. The magnet is coupled with the optical coherence tomography device so that changes in the magnetic field are coordinated with collection of data by the optical coherence tomography device. This device may be used to examine a sample by spectral-domain magnetomotive optical coherence tomography, which includes examining the sample with a spectral-domain optical coherence tomography device, to collect optical coherence tomography data. The sample contains magnetic particles, and the magnetic particles are subjected to a changing magnetic field during the examining.
FILED Monday, March 03, 2008
APPL NO 12/041366
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/497
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751528 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina (Chapel Hill, North Carolina);  North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Otto Z. Zhou (Chapel Hill, North Carolina);  Guang Yang (Minneapolis, Minnesota);  Jianping Lu (Chapel Hill, North Carolina);  David Lalush (Cary, North Carolina)
ABSTRACT Stationary x-ray digital breast tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object.
FILED Friday, July 18, 2008
APPL NO 12/176056
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751981 Famili et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Imandokht Famili (San Diego, California);  Jochen Förster (Copenhagen V, Denmark);  Pengcheng Fu (Honolulu, Hawaii);  Jens B. Nielsen (Charlottenlund, Denmark);  Bernhard O. Palsson (La Jolla, California)
ABSTRACT The invention provides an in silico model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive of a S. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silico S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.
FILED Wednesday, October 02, 2002
APPL NO 10/263901
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751984 Tang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Mathematical Sciences (DMS)
APPLICANT(S)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Dalin Tang (Shrewsbury, Massachusetts)
ABSTRACT A method and a computer system, for providing an assessment for disease status of a disease, such as a cardiovascular disease, employ construction of image-based 3D computational model of an organ representative of the disease status; computationally obtaining a certain mechanical distribution using the 3D-organ model; and computational, quantitative analysis of the mechanical distribution to provide an assessment for disease status of a disease. The image-based 3D computational model includes a fluid-structure interaction and multiple components within the organ.
FILED Thursday, December 08, 2005
APPL NO 11/296943
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07749765 Demas et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) James N. Demas (Charlottesville, Virginia);  Wenying Xu (Charlottesville, Virginia)
ABSTRACT The present invention provides compositions and methods for extracting, isolating, and measuring lead dissolved in aqueous solutions, including water.
FILED Thursday, August 03, 2006
APPL NO 11/997630
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/77
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749769 Hunt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Donald F Hunt (Charlottesville, Virginia);  Joshua J. Coon (Madison, Wisconsin);  John Edward Philip Syka (Charlottesville, Virginia)
ABSTRACT The present invention relates to a new method for identifying polypeptides by deducing the amino acid sequence of the carboxy and amino termini by a mass spectrometer analysis. The method comprises the steps of dissociating highly charged peptide precursor ions (e.g., z>4) using electron transfer dissociation inducing anions followed by removal of those reagents and introduction of a second, proton transfer inducing anion type. The second PTR reaction duration is adjusted to convert the ETD products to primarily the +1 charge-state to reduce the highly charged c and z-type fragments, producing an m/z spectrum containing a series of c and z-type fragment ions that are easily interpreted to reveal the sequence of the amino and carboxy terminus, respectively.
FILED Friday, October 07, 2005
APPL NO 11/664661
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/173
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749922 Bezryadin et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Alexey Bezryadin (Champaign, Illinois);  Mikas Remeika (Urbana, Illinois)
ABSTRACT The present invention provides structures and devices comprising conductive segments and conductance constricting segments of a nanowire, such as metallic, superconducting or semiconducting nanowire. The present invention provides structures and devices comprising conductive nanowire segments and conductance constricting nanowire segments having accurately selected phases including crystalline and amorphous states, compositions, morphologies and physical dimensions, including selected cross sectional dimensions, shapes and lengths along the length of a nanowire. Further, the present invention provides methods of processing nanowires capable of patterning a nanowire to form a plurality of conductance constricting segments having selected positions along the length of a nanowire, including conductance constricting segments having reduced cross sectional dimensions and conductance constricting segments comprising one or more insulating materials such as metal oxides.
FILED Thursday, May 04, 2006
APPL NO 11/417370
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/795
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750103 Emrick et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The University of Massachusetts (Boston, Massachusetts);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Todd Shannon Emrick (South Deerfield, Massachusetts);  Kurt Breitenkamp (Northampton, Massachusetts)
ABSTRACT Azidoaryl-substituted cyclooctene monomers and synthesized and used in the preparation of various copolymers. Among these copolymers are those prepared from ring-opening metathesis polymerization of cyclooctene, polyethylene glycol-substituted cyclooctene, and azidoaryl-substituted cyclooctene. These copolymers are useful in the formation of crosslinked films that reduce fouling of water purification membranes.
FILED Friday, September 07, 2007
APPL NO 11/899869
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
526/288
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US 07750134 Godzik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S)
ASSIGNEE(S) Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Adam Godzik (San Diego, California);  John C. Reed (Rancho Santa Fe, California)
ABSTRACT The invention provides isolated SUMO-specific protease-like (or “SSP”) domain-containing polypeptides from microorganisms, including bacteria, protozoans and yeast, including Escherichia, Salmonella, Pseudomonas, Chlamydia, Plasmodium, Trypanosma, Mesorhizobium, Rickettsia, Cryptosporidium and Candida species. The invention further provides modifications of such polypeptides, functional fragments therefrom, encoding nucleic acid molecules and specific antibodies. Also provided are methods for identifying polypeptides and compounds that associate with or modulate the activity of the SSP domain-containing polypeptides. Further provided are methods of modulating a biological activity in a cell, and treating pathological conditions, using the described nucleic acid molecules, polypeptides and compounds.
FILED Wednesday, November 20, 2002
APPL NO 10/301533
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.200
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US 07750135 Zeikus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) J. Gregory Zeikus (Okemos, Michigan);  Karla I. Ziegelmann-Fjeld (Lansing, Michigan);  Claire Vieille (Lansing, Michigan)
ABSTRACT The present invention relates to compositions and methods utilizing thermostable and novel alcohol dehydrogenase enzymes for biosynthesizing chiral specific molecules for use as precursor molecules in synthesizing pharmaceutical compounds. Particularly, in preferred embodiments, the invention relates to directed engineering of an enzymatic catalytic site of an alcohol dehydrogenase enzyme gene for enhancing enantioselectivity for (S)-enantiomer substrate catalytic activity for providing aryl (S)-enantiomer products in stereomeric excess.
FILED Friday, July 27, 2007
APPL NO 11/881690
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750172 Grubbs et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Robert H. Grubbs (S. Pasadena, California);  Peter Schwab (East Hanover, New Jersey);  Sonbinh T. Nguyen (Evanston, Illinois)
ABSTRACT Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene compounds are of the formula
where M is Os or Ru; R1 is hydrogen; R is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, and substituted or unsubstituted aryl; X and X1 are independently selected from any anionic ligand; and L and L1 are independently selected from any neutral electron donor. The ruthenium and osmium carbene compounds of the present invention may be synthesized using diazo compounds, by neutral electron donor ligand exchange, by cross metathesis, using acetylene, using cumulated olefins, and in a one-pot method using diazo compounds and neutral electron donors. The ruthenium and osmium carbene compounds of the present invention may be used to catalyze olefin metathesis reactions including, but not limited to, ROMP, RCM, depolymerization of unsaturated polymers, synthesis of telechelic polymers, and olefin synthesis.
FILED Tuesday, October 30, 2007
APPL NO 11/929358
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
556/21
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750175 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Qinglan Huang (Libertyville, Illinois)
ABSTRACT New organic light-emitting diodes and related hole transport compounds and methods for fabrication, using siloxane self-assembly techniques.
FILED Tuesday, August 24, 2004
APPL NO 10/924730
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Organic compounds
556/424
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750294 Bright et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Frank V. Bright (Williamsville, New York);  William G. Holthoff (Tonawanda, New York);  Elizabeth C. Tehan (Buffalo, New York)
ABSTRACT A photonic sensor system is provided. The system generally includes a beta emission source, optionally, a scintillation layer, and a luminophore-containing sensory layer. The system can be embodied in a particle. Also provided are photonic sensor strategies which are highly accurate and photonic sensors which are highly stable.
FILED Thursday, March 10, 2005
APPL NO 11/076729
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/308
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751057 Oldenburg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Amy L. Oldenburg (Urbana, Illinois);  Stephen A. Boppart (Champaign, Illinois);  Vasilica Crecea (Urbana, Illinois);  Xing Liang (Urbana, Illinois)
ABSTRACT A spectral-domain magnetomotive optical coherence tomography apparatus, includes (a) a spectral-domain optical coherence tomography device, and (b) a magnet. The magnet is coupled with the optical coherence tomography device so that changes in the magnetic field are coordinated with collection of data by the optical coherence tomography device. This device may be used to examine a sample by spectral-domain magnetomotive optical coherence tomography, which includes examining the sample with a spectral-domain optical coherence tomography device, to collect optical coherence tomography data. The sample contains magnetic particles, and the magnetic particles are subjected to a changing magnetic field during the examining.
FILED Monday, March 03, 2008
APPL NO 12/041366
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/497
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751654 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Michal Lipson (Ithaca, New York);  Bradley Schmidt (Ithaca, New York);  Sameer Pradhan (Portland, Oregon);  Qianfan Xu (Ithaca, New York)
ABSTRACT A silicon electro-optic waveguide modulator is formed using a metal-oxide-semiconductor (MOS) configuration. Various embodiments are described using different modes of operation of the MOS diode and gate oxide thicknesses. In one example, a high-speed submicron waveguide active device is formed using silicon-on-insulator. A micro-ring resonator intensity-modulator exhibits switching times on the order of tens of pS with modulation depth of 73% with a bias voltage of 5 volts.
FILED Friday, March 03, 2006
APPL NO 11/367756
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751984 Tang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Mathematical Sciences (DMS)
APPLICANT(S)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Dalin Tang (Shrewsbury, Massachusetts)
ABSTRACT A method and a computer system, for providing an assessment for disease status of a disease, such as a cardiovascular disease, employ construction of image-based 3D computational model of an organ representative of the disease status; computationally obtaining a certain mechanical distribution using the 3D-organ model; and computational, quantitative analysis of the mechanical distribution to provide an assessment for disease status of a disease. The image-based 3D computational model includes a fluid-structure interaction and multiple components within the organ.
FILED Thursday, December 08, 2005
APPL NO 11/296943
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752233 Vempala et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Yale University (New Haven, Connecticut)
INVENTOR(S) Santosh Vempala (Atlanta, Georgia);  Grant Wang (Mt. View, California);  Ravi Kannan (Hamden, Connecticut);  David Cheng (New York, New York)
ABSTRACT Described are techniques for clustering a data set of objects. Divide phase processing is performed to partition the data set into two or more partitions forming a hierarchy of the objects. Merge phase processing may be performing using the hierarchy to determine one or more disjoint clusters of objects of the data set. Optional preprocessing may be performed to determine weights for one or more features of an object.
FILED Thursday, March 29, 2007
APPL NO 11/731008
ART UNIT 2163 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/802
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752332 Jiang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Anxiao Jiang (College Station, Texas);  Jie Gao (Stoney Brook, New York);  Jehoshua Bruck (La Canada, California)
ABSTRACT Routing in a wireless network of communication devices that are located within a network boundary moves network traffic from a first communication device to a second communication device. A geometric indicator of network connectivity is constructed that identifies a curve on which network nodes are located and a network location for each node of the wireless network is determined, so that the network location of a node p identifies a node on the geometric indicator curve that is closest to the node p and indicates connectivity from the node p to the closest node of the geometric indicator curve. A routing scheme is determined, to route in the wireless network from the first communication device to the second communication device based on the respective determined network locations for the first and second communication devices.
FILED Tuesday, April 18, 2006
APPL NO 11/379196
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/238
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07749432 Muralidharan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Govindarajan Muralidharan (Knoxville, Tennessee);  Vinod Kumar Sikka (Oak Ridge, Tennessee);  Philip J. Maziasz (Oak Ridge, Tennessee);  Roman I. Pankiw (Greensburg, Pennsylvania)
ABSTRACT A cast, austenitic steel composed essentially of, expressed in weight percent of the total composition, about 0.4 to about 0.7 C, about 20 to about 30 Cr, about 20 to about 30 Ni, about 0.5 to about 1 Mn, about 0.6 to about 2 Si, about 0.05 to about 1 Nb, about 0.05 to about 1 W, about 0.05 to about 1.0 Mo, balance Fe, the steel being essentially free of Ti and Co, the steel characterized by at least one microstructural component selected from the group consisting of MC, M23C6, and M(C, N).
FILED Wednesday, January 19, 2005
APPL NO 11/038923
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Alloys or metallic compositions
420/53
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749922 Bezryadin et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Alexey Bezryadin (Champaign, Illinois);  Mikas Remeika (Urbana, Illinois)
ABSTRACT The present invention provides structures and devices comprising conductive segments and conductance constricting segments of a nanowire, such as metallic, superconducting or semiconducting nanowire. The present invention provides structures and devices comprising conductive nanowire segments and conductance constricting nanowire segments having accurately selected phases including crystalline and amorphous states, compositions, morphologies and physical dimensions, including selected cross sectional dimensions, shapes and lengths along the length of a nanowire. Further, the present invention provides methods of processing nanowires capable of patterning a nanowire to form a plurality of conductance constricting segments having selected positions along the length of a nanowire, including conductance constricting segments having reduced cross sectional dimensions and conductance constricting segments comprising one or more insulating materials such as metal oxides.
FILED Thursday, May 04, 2006
APPL NO 11/417370
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/795
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750199 Tucker
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Mark D. Tucker (Albuquerque, New Mexico)
ABSTRACT A decontamination formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a sorbent additive, and water. A highly adsorbent sorbent additive (e.g., amorphous silica, sorbitol, mannitol, etc.) is used to “dry out” one or more liquid ingredients into a dry, free-flowing powder that has an extended shelf life, and is more convenient to handle and mix in the field. The formulation can be pre-mixed and pre-packaged as a multi-part kit system, where one or more of the parts are packaged in a powdered, granulated form for ease of handling and mixing in the field.
FILED Monday, August 06, 2007
APPL NO 11/834259
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Hazardous or toxic waste destruction or containment
588/320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750234 Deng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) The University Of Toledo (Toledo, Ohio)
INVENTOR(S) Xunming Deng (Sylvania, Ohio);  Liwei Xu (Sylvania, Ohio)
ABSTRACT An integrated photoelectrochemical (PEC) cell generates hydrogen and oxygen from water while being illuminated with radiation. The PEC cell employs a liquid electrolyte, a multi-junction photovoltaic electrode, and a thin ion-exchange membrane. A PEC system and a method of making such PEC cell and PEC system are also disclosed.
FILED Monday, May 23, 2005
APPL NO 11/134929
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/252
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750297 Chow et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Lee Chow (Orlando, Florida);  Guangyu Chai (Orlando, Florida);  Thomas Schenkel (San Francisco, California)
ABSTRACT Apparatus, methods, systems and devices for fabricating individual CNT collimators. Micron size fiber coated CNT samples are synthesized with chemical vapor deposition method and then the individual CNT collimators are fabricated with focused ion beam technique. Unfocused electron beams are successfully propagated through the CNT collimators. The CNT nano-collimators are used for applications including single ion implantation and in high-energy physics, and allow rapid, reliable testing of the transmission of CNT arrays for transport of molecules.
FILED Friday, March 09, 2007
APPL NO 11/716258
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/311
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750325 Akers
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) Douglas W. Akers (Idaho Falls, Idaho)
ABSTRACT Apparatus for producing and storing positrons may include a trap that defines an interior chamber therein and that contains an electric field and a magnetic field. The trap may further include a source material that includes atoms that, when activated by photon bombardment, become positron emitters to produce positrons. The trap may also include a moderator positioned adjacent the source material. A photon source is positioned adjacent the trap so that photons produced by the photon source bombard the source material to produce the positron emitters. Positrons from the positron emitters and moderated positrons from the moderator are confined within the interior chamber of the trap by the electric and magnetic fields. Apparatus for producing and storing protons are also disclosed.
FILED Wednesday, November 28, 2007
APPL NO 11/946512
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/493.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750425 Forrest et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Guodan Wei (Ann Arbor, Michigan)
ABSTRACT A plurality of layers of a first semiconductor material and a plurality of dots-in-a-fence barriers disposed in a stack between a first electrode and a second electrode. Each dots-in-a-fence barrier consists essentially of a plurality of quantum dots of a second semiconductor material embedded between and in direct contact with two layers of a third semiconductor material. Wave functions of the quantum dots overlap as at least one intermediate band. The layers of the third semiconductor material are arranged as tunneling barriers to require a first electron and/or a first hole in a layer of the first material to perform quantum mechanical tunneling to reach the second material within a respective quantum dot, and to require a second electron and/or a second hole in a layer of the first semiconductor material to perform quantum mechanical tunneling to reach another layer of the first semiconductor material.
FILED Monday, November 13, 2006
APPL NO 11/598006
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/441
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07750633 Pines et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alexander Pines (Berkeley, California);  Dimitrios Sakellariou (Billancourt, France);  Carlos A. Meriles (Fort Lee, New Jersey);  Andreas H. Trabesinger (London, United Kingdom)
ABSTRACT A method and system of magnetic resonance imaging does not need a large homogenous field to truncate a gradient field. Spatial information is encoded into the spin magnetization by allowing the magnetization to evolve in a non-truncated gradient field and inducing a set of 180 degree rotations prior to signal acquisition.
FILED Thursday, July 21, 2005
APPL NO 11/570357
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751695 Decker
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Derek E. Decker (Byron, California)
ABSTRACT A new technique for recording a series of images of a high-speed event (such as, but not limited to: ballistics, explosives, laser induced changes in materials, etc.) is presented. Such technique(s) makes use of a lenslet array to take image picture elements (pixels) and concentrate light from each pixel into a spot that is much smaller than the pixel. This array of spots illuminates a detector region (e.g., film, as one embodiment) which is scanned transverse to the light, creating tracks of exposed regions. Each track is a time history of the light intensity for a single pixel. By appropriately configuring the array of concentrated spots with respect to the scanning direction of the detection material, different tracks fit between pixels and sufficient lengths are possible which can be of interest in several high-speed imaging applications.
FILED Tuesday, June 12, 2007
APPL NO 11/818189
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Photography
396/20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07751878 Merkle et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Peter B. Merkle (Sandia Park, New Mexico);  Curtis M. Johnson (Sandia Park, New Mexico);  Wendell B. Jones (Albuquerque, New Mexico);  Gerold Yonas (Albuquerque, New Mexico);  Adele B. Doser (Albuquerque, New Mexico);  David J. Warner (Rancho Santa Fe, California)
ABSTRACT A method of and apparatus for monitoring and intervening in, in real time, a collaboration between a plurality of subjects comprising measuring indicia of physiological and cognitive states of each of the plurality of subjects, communicating the indicia to a monitoring computer system, with the monitoring computer system, comparing the indicia with one or more models of previous collaborative performance of one or more of the plurality of subjects, and with the monitoring computer system, employing the results of the comparison to communicate commands or suggestions to one or more of the plurality of subjects.
FILED Thursday, November 10, 2005
APPL NO 11/271214
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/545
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07748590 Reatherford et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Ford Global Technologies, LLC (Dearborn, Michigan);  Jaguar Cars Limited (Whitley, Coventry, United Kingdom)
INVENTOR(S) Larry Reatherford (Clarkston, Michigan);  Elizabeth T. Hetrick (Ann Arbor, Michigan);  Daniel E. Wilkosz (Saline, Michigan);  Jan Skogsmo (Molndal, Sweden);  Joseph Walsh (Quarryville, Pennsylvania)
ABSTRACT An ultrasonic welding apparatus having an extractable sonotrode. The sonotrode having a non-threaded outer peripheral surface and a tapered mating surface that meets with a correspondingly tapered aperture formed in the end of the reed of the ultrasonic welding apparatus. In the preferred embodiment the ultrasonic welding apparatus includes a sonotrode removal mechanism for extracting the sonotrode from the reed.
FILED Monday, May 16, 2005
APPL NO 11/129775
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal fusion bonding
228/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749396 Chow et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Eugene M. Chow (Fremont, California);  William S. Wong (San Carlos, California);  Michael Chabinyc (Burlingame, California);  Ana Claudia Arias (San Carlos, California)
ABSTRACT A process for fabricating fine features such as small gate electrodes on a transistor. The process involves the jet-printing of a mask and the plating of a metal to fabricate sub-pixel and standard pixel size features in one layer. Printing creates a small sub-pixel size gap mask for plating a fine feature. A second printed mask may be used to protect the newly formed gate and etch standard pixel size lines connecting the small gates.
FILED Friday, March 24, 2006
APPL NO 11/388731
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Etching a substrate: Processes
216/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749564 Feng et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Caterpillar Inc. (Peoria, Illinois)
INVENTOR(S) Bao Feng (Dunlap, Illinois);  Mahmoud Taher (Pooria, Illinois);  Andrew G. Shull (Washington, Illinois);  Eric P. Carlson (Christiansburg, Virginia);  Conrad C. Klepper (Radford, Virginia)
ABSTRACT The present disclosure provides a method for producing a coating. The method may include providing a substrate material and initiating a coating-deposition process to apply a coating material to the substrate material to produce a coating on the substrate material, wherein the coating includes a diamond-like carbon coating. The method may further include monitoring an intensity of hydrogen-alpha emission of a plasma produced during the coating-deposition process and adjusting at least one process variable of the coating-deposition process to facilitate production of the diamond-like carbon coating.
FILED Friday, March 31, 2006
APPL NO 11/396116
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/249.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749916 Wong et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) William Wong (San Carlos, California);  Scott Limb (Palo Alto, California);  Michael Chabinyc (Burlingame, California);  Beverly Russo (Sunnyvale, California);  Rene Lujan (Sunnyvale, California)
ABSTRACT A digital lithographic process first deposits a mask layer comprised of print patterned mask features. The print patterned mask features define gaps into which a target material may be deposited, preferably through a digital lithographic process. The target material is cured or hardened, if necessary, into target features. The mask layer is then selectively removed. The remaining target features may then be used as exposure or etch masks, physical structures such as fluid containment elements, etc. Fine feature widths, narrower the minimum width of the print patterned mask features, may be obtained while realizing the benefits of digital lithography in the manufacturing process.
FILED Tuesday, March 11, 2008
APPL NO 12/046242
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/758
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07749341 Noebe et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Ronald Dean Noebe (Medina, Ohio);  Susan L. Draper (Westlake, Ohio);  Michael V. Nathal (Strongsville, Ohio);  Edwin A. Crombie (West Chester, Pennsylvania)
ABSTRACT A composition of the invention is a high temperature shape memory alloy having high work output, and is made from (Ni+Pt+Y)xTi(100-x), wherein x is present in a total amount of 49-55 atomic %, Pt is present in a total amount of 10-30 atomic %, Y is one or more of Au, Pd, and Cu and is present in a total amount of 0 to 10 atomic %. The alloy has a matrix phase wherein the total concentration of Ni, Pt, and the one or more of Pd, Au, and Cu is greater than 50 atomic %.
FILED Monday, March 06, 2006
APPL NO 11/370391
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal treatment
148/402
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749799 Pain
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Bedabrata Pain (Los Angeles, California)
ABSTRACT Methods for bringing or exposing metal pads or traces to the backside of a backside-illuminated imager allow the pads or traces to reside on the illumination side for electrical connection. These methods provide a solution to a key packaging problem for backside thinned imagers. The methods also provide alignment marks for integrating color filters and microlenses to the imager pixels residing on the frontside of the wafer, enabling high performance multispectral and high sensitivity imagers, including those with extremely small pixel pitch. In addition, the methods incorporate a passivation layer for protection of devices against external contamination, and allow interface trap density reduction via thermal annealing. Backside-illuminated imagers with illumination side electrical connections are also disclosed.
FILED Wednesday, November 15, 2006
APPL NO 11/600583
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/75
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752608 Hinchey et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Michael G. Hinchey (Bowie, Maryland);  James L. Rash (Davidsonville, Maryland);  John D. Erickson (Midland, Texas);  Denis Gracinin (Blacksburg, Virginia);  Christopher A. Rouff (Beltsville, Maryland)
ABSTRACT Systems, methods and apparatus are provided through which in some embodiments, domain knowledge is translated into a knowledge-based system. In some embodiments, a formal specification is derived from rules of a knowledge-based system, the formal specification is analyzed, and flaws in the formal specification are used to identify and correct errors in the domain knowledge, from which a knowledge-based system is translated.
FILED Friday, August 12, 2005
APPL NO 11/203586
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/136
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07751519 Farbarik et al.
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S)
ASSIGNEE(S) Cray Inc. (Seattle, Washington)
INVENTOR(S) Raymond J. Farbarik (Seattle, Washington);  Michael Steinberger (Chippewa Falls, Wisconsin)
ABSTRACT An apparatus comprising a first multiplexer circuit (MUX) to receive a plurality of clock phase signals at a corresponding plurality of MUX inputs and to output a first clock signal and a second clock signal that are out of phase with each other, a phase delay circuit to receive the output of the first MUX and to generate adjusted first and second clock signals that have reduced phase error with respect to detected edges of incoming data, an output MUX to receive the adjusted first and second clock signals and to output a recovered clock signal, and a control circuit coupled to output MUX select inputs. The control circuit includes logic circuitry to select the first adjusted clock signal as the recovered clock signal and to select the second adjusted clock signal as the recovered clock signal when the first adjusted clock signal nears a phase limit due to drift of the detected data edges. Other devices and methods are disclosed.
FILED Monday, May 14, 2007
APPL NO 11/748368
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/371
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07752239 Richards et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York);  The United States of America as represented by National Security Agency (Washington, District of Columbia)
INVENTOR(S) Elizabeth S. Richards (Columbia, Maryland);  Sandeep M. Uttamchandani (San Jose, California);  Li Yin (Albany, California)
ABSTRACT The embodiments of the invention provide a method, computer program product, etc. for risk-modulated proactive data migration for maximizing utility. More specifically, a method of planning data migration for maximizing utility of a storage infrastructure that is running and actively serving at least one application includes selecting a plurality of potential data items for migration and selecting a plurality of potential migration destinations to which the potential data items can be moved. Moreover, the method selects a plurality of potential migration speeds at which the potential data items can be moved and selects a plurality of potential migration times at which the potential data items can be moved to the potential data migration destinations. The selecting of the plurality of potential migration speeds selects a migration speed below a threshold speed, wherein the threshold speed defines a maximum system utility loss permitted.
FILED Thursday, April 03, 2008
APPL NO 12/061764
ART UNIT 2627 — Selective Visual Display Systems
CURRENT CPC
Data processing: Database and file management or data structures
77/812
VIEW PATENT @ USPTO:  Full Text   PDF 
US D619098 Mike
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Director National Security Agency (Washington, District of Columbia)
INVENTOR(S) William A. Mike (Baltimore, Maryland)
ABSTRACT
FILED Tuesday, July 21, 2009
APPL NO 29/315759
ART UNIT 2911 — Design
CURRENT CPC
Equipment for production, distribution, or transformation of energy
D13/152
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07749511 Gustafson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) EndoBiologics, Incorporated (Missoula, Montana)
INVENTOR(S) Gary L. Gustafson (Missoula, Montana);  Dan C. DeBorde (Missoula, Montana)
ABSTRACT The present invention provides an immunogenic conjugate comprising biologically deacylated gram-negative bacterial moieties linked to D. discoideum proteinase 1, as well as novel subunits thereof, and methods of making and using the conjugates in vaccines to treat sepsis and other infectious complications.
FILED Tuesday, November 15, 2005
APPL NO 11/274847
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/234.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07749706 Bacher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Promega Corporation (Madison, Wisconsin)
INVENTOR(S) Jeffrey W. Bacher (Madison, Wisconsin);  Laura Flanagan (Fort Atkinson, Wisconsin);  Nadine Nassif (Madison, Wisconsin)
ABSTRACT Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits of the present invention can be used to detect or diagnose diseases associated with microsatellite instability, such as certain types of cancer.
FILED Tuesday, December 19, 2006
APPL NO 11/612567
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of State (DOS) 

US 07749501 Gelfand
FUNDED BY
Department of State (DOS)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Charlestown, Massachusetts)
INVENTOR(S) Jeffrey A. Gelfand (Cambridge, Massachusetts)
ABSTRACT Provided are fusion polypeptides comprising an engineered antibody and a stress protein that bind to antigens with high affinity, are highly immunogenic, exhibit MHC class I priming and are able to be produced in non-mammalian cells, such as E. coli.
FILED Monday, August 04, 2008
APPL NO 12/185631
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/133.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07748623 Barber
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Columbus, Ohio)
INVENTOR(S) Jeffrey B. Barber (Vineland, New Jersey)
ABSTRACT A container screener apparatus that uses container barcode (e.g. Universal Product Code) scanning, and one or more container and/or container content property measurements (e.g. photograph, description, weighing, acoustic measurement), and container comparison data stored in a database to determine if a container passes or fails a container screening based on predetermined pass/fail criteria.
FILED Thursday, November 08, 2007
APPL NO 11/983556
ART UNIT 2887 — Optics
CURRENT CPC
Registers
235/383
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 07749983 Hostetler et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S) Chimerix, Inc. (Durham, North Carolina);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Karl Y. Hostetler (Del Mar, California);  James R. Beadle (San Diego, California);  Jacqueline Ruiz (San Diego, California);  Merrick R. Almond (Apex, North Carolina);  George R. Painter (Chapel Hill, North Carolina);  Timothy A. Riley (Raleigh, North Carolina);  Paula Francom (Salem, Utah)
ABSTRACT The present invention relates to phosphonate, nucleoside phosphonate or nucleoside phosphate compounds, compositions containing them, processes for obtaining them, and their use in treating a variety of medical disorders, in particular viral infections, cancers and the like.
FILED Wednesday, April 18, 2007
APPL NO 11/736614
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/79
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 07750962 Anthony
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Michael P. Anthony (Andover, Massachusetts)
ABSTRACT The present invention provides an apparatus for adding or subtracting an amount charge to or from a charge packet in a CCD as the packet traverses the CCD. The apparatus uses a “wire transfer” device structure to perform the addition or subtraction of charge during the charge packets traversal across the device. A pair of electrically interconnected diffusions are incorporated within the charge couple path to provide an amount of charge which can be added or subtracted from packets as the packets traverse the CCD.
FILED Tuesday, February 20, 2007
APPL NO 11/676640
ART UNIT 2622 — Selective Visual Display Systems
CURRENT CPC
Television
348/311
VIEW PATENT @ USPTO:  Full Text   PDF 

National Reconnaissance Office (NRO) 

US 07750235 Scher et al.
FUNDED BY
National Reconnaissance Office (NRO)
APPLICANT(S)
ASSIGNEE(S) Nanosys, Inc. (Palo Alto, California)
INVENTOR(S) Erik C. Scher (San Francisco, California);  Mihai Buretea (San Francisco, California);  Calvin Y. H. Chow (Portola Valley, California);  Stephen A. Empedocles (Menlo Park, California);  Andreas P. Meisel (San Francisco, California);  J. Wallace Parce (Palo Alto, California)
ABSTRACT Nanocomposite photovoltaic devices are provided that generally include semiconductor nanocrystals as at least a portion of a photoactive layer. Photovoltaic devices and other layered devices that comprise core-shell nanostructures and/or two populations of nanostructures, where the nanostructures are not necessarily part of a nanocomposite, are also features of the invention. Varied architectures for such devices are also provided including flexible and rigid architectures, planar and non-planar architectures and the like, as are systems incorporating such devices, and methods and systems for fabricating such devices. Compositions comprising two populations of nanostructures of different materials are also a feature of the invention.
FILED Friday, August 04, 2006
APPL NO 11/499599
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/252
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07748606 Mikolajczyk et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Ryszard K. Mikolajczyk (Chicago, Illinois);  Taurris D. Baskerville (Schaumburg, Illinois)
ABSTRACT An apparatus and method for enhancing the security of a cluster box unit which includes a protective enclosure, internal cabinetry, door, hinge and locking system. The cluster box unit may also include outgoing mail compartment doors that are heavily constructed and rigidly reinforced, with the locks carried thereon protectively shielded, and with the extensible bolts of these locks being engaged by brackets that not only lock the outgoing mail compartment doors but also the master loading doors of the cluster box units. The cluster box unit may also include master loading doors are provided with hinges that extend the full height of the doors—hinges that are defined by pivotally interfitting elements of extrusions that very sturdily mount the master loading doors, that prevent prying or bending the doors in the vicinities of their hinges. The interfitting elements of the hinge extrusions also permit the doors to be installed on their surrounding door frames quickly and easily, and permit one or both of the master loading doors to be quickly and easily removed for service or replacement when necessary.
FILED Wednesday, June 29, 2005
APPL NO 11/168302
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Deposit and collection receptacles
232/45
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07750125 Zauderer et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Maurice Zauderer (Pittsford, New York);  Elizabeth E. Evans (Bloomfield, New York)
ABSTRACT The present invention relates to a novel human gene that is differentially expressed in human carcinoma. More specifically, the present invention relates to a polynucleotide encoding a novel human polypeptide named C35 that is overexpressed in human breast and bladder carcinoma. This invention also relates to C35 polypeptide, in particular C35 peptide epitopes and C35 peptide epitope analogs, as well as vectors, host cells, antibodies directed to C35 polypeptides, and the recombinant methods for producing the same. The present invention further relates to diagnostic methods for detecting carcinomas, including human breast carcinomas. The present invention further relates to the formulation and use of the C35 gene and polypeptides, in particular C35 peptide epitopes and C35 peptide epitope analogs, in immunogenic compositions or vaccines, to induce antibody or cell-mediated immunity against target cells, such as tumor cells, that express the C35 gene. The invention further relates to screening methods for identifying agonists and antagonists of C35 activity.
FILED Friday, August 17, 2007
APPL NO 11/892017
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.100
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, July 06, 2010.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100706.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

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