FedInvent™ Patents
Patent Details for Tuesday, August 17, 2010
This page was updated on Monday, March 27, 2023 at 01:53 AM GMT
Department of Health and Human Services (HHS)
US 07775368 | Schwartz et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David Charles Schwartz (Madison, Wisconsin); Eileen T. Dimalanta (Madison, Wisconsin); Juan J. de Pablo (Madison, Wisconsin) |
ABSTRACT | Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten, align, separate, and/or sort the polymeric molecules. The polymeric molecules may be analyzed and/or manipulated in the carrier liquid or attached to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge. |
FILED | Friday, October 17, 2003 |
APPL NO | 10/688416 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Classifying, separating, and assorting solids 29/1 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775469 | Poznansky et al. |
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ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Mark C. Poznansky (Charlestown, Massachusetts); Andrew D. Luster (Wellesley, Massachusetts); David T. Scadden (Weston, Massachusetts) |
ABSTRACT | This invention relates to methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention relates to methods and compositions for modulating movement of cells of hematopoietic, neural, epithelial, or mesenchymal origin, in a specific site in a subject. The foregoing are useful, inter alia, in the treatment of conditions characterized by a need to modulate migratory-cell movement associated with specific sites in a subject. More specifically, specific sites include sites of inflammation and modulation of migratory-cell movement is movement away from an agent source, or repulsion. Other sites include tumor sites, sites of pathogenic infection, and germ cell bearing sites. |
FILED | Thursday, April 20, 2006 |
APPL NO | 11/407477 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Winding, tensioning, or guiding 242/85.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775979 | Thomenius et al. |
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ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Kai E. Thomenius (Clifton Park, New York); Robert Gideon Wodnicki (Niskayuna, New York); Ye-Ming Li (Schenectady, New York) |
ABSTRACT | An ultrasonic transducer probe having a highly integrated interface circuit array. Low-voltage transmit control signals from the system are transmitted on the system transmit channels via the ultrasound probe cable and into the interface circuit array. These transmit control signals are routed through the interface circuit array using a dense switching matrix. Once the low-voltage transmit control signals reach individual cells within the interface array, they are decoded and used to control local high-voltage pulser circuits to drive individual ultrasound transducer elements made up of selected subelements that are co-integrated with the interface electronics. The interface cell circuitry further comprises a high-voltage transmit/receive switch, which is closed when the high-voltage pulser is transmitting to protect the low-voltage components. |
FILED | Wednesday, June 29, 2005 |
APPL NO | 11/172599 |
ART UNIT | 3768 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Surgery 6/437 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776197 | Zhou |
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ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Dao Min Zhou (Saugus, California) |
ABSTRACT | An electrode surface coating and method for manufacturing the electrode surface coating comprising a conductive substrate; and one or more surface coatings comprising one or more of the following metals titanium, niobium, tantalum, ruthenium, rhodium, iridium, palladium, or gold, or an alloy of two or more metals, or a combination of two or more alloys or metal layers thereof having an increase in the surface area of 5 times to 500 times of the corresponding surface area resulting from the basic geometric shape. |
FILED | Tuesday, December 30, 2008 |
APPL NO | 12/346571 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/99 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776292 | Wilson et al. |
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ASSIGNEE(S) | CDIC, Inc. (Atlanta, Georgia); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); CDG Research Corporation (Bethlehem, Pennsylvania) |
INVENTOR(S) | Deborah E. Wilson (Dunn Loring, Virginia); Katherine K. Lock (Bethesda, Maryland); Murray L. Cohen (Fort Worth, Texas); Thomas E. McWhorter (Allentown, Pennsylvania); Aaron A. Rosenblatt (New York, New York); Theodore J. Traum (Rio Rancho, New Mexico) |
ABSTRACT | The present disclosure relates to the decontamination of articles contaminated (or thought to be contaminated) with bioweapons, such as methods and apparatus for decontaminating articles contaminated with sporualated bioweapons. In some embodiments, the methods are methods of decontaminating an environment, for example a room or building contaminated with a bioweapon. |
FILED | Thursday, January 13, 2005 |
APPL NO | 10/597191 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/295 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776313 | Fish et al. |
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ASSIGNEE(S) | University Health Network (Ontario, Canada); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Eleanor Fish (Toronto, Canada); Carole Galligan (Scarborough, Canada); Kathy Siminovitch (Toronto, Canada); Omar Perez (San Francisco, California); Edward Keystone (Toronto, Canada); Vivian Bykerk (Toronto, Canada) |
ABSTRACT | The invention provides a novel cell that is a precursor of a fibroblast-like synovial cell. The novel cell is a circulating synovial tissue cell that stains positive for collagen, CD34, CD45, prolyl 4-hydroxylase and CD14. The invention also relates to methods of diagnosing or monitoring rheumatoid arthritis and/or osteoarthritis using gene expression profiles, protein expression profiles, and/or protein phosphorylation profiles of different cell types, including the novel precursor, CD3+ cells, synovial tissue fibroblast-like synovial cells and fibrocytes. The invention also includes methods to identify substances to treat or prevent rheumatoid arthritis and/or osteoarthritis. |
FILED | Friday, May 25, 2007 |
APPL NO | 11/807088 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776330 | Yazaki et al. |
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ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Paul J. Yazaki (Glendale, California); Mark A. Sherman (Pasadena, California); John E. Shively (Arcadia, California); Andrew A. Raubitschek (San Marino, California); Anna M. Wu (Sherman Oaks, California) |
ABSTRACT | Embodiments of the present invention utilize a more efficient CDR grafting technique to generate humanized versions of the T84.66 antibody. The technique used to generate these antibodies utilizes crystallographic structural data to select an immunoglobulin framework having maximum structural overlap with a non-human donor molecule. This technique was used to develop humanized T84.66 antibodies exhibiting in vitro binding affinity and specificity for carcinoembryonic antigen (CEA) nearly identical to that of T84.66 and the ability to specifically target tumors expressing CEA in vivo. |
FILED | Tuesday, September 25, 2007 |
APPL NO | 11/861093 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776334 | Scadden et al. |
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ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | David T. Scadden (Weston, Massachusetts); Laura M. Calvi (Rochester, New York); Gregor Adams (Boston, Massachusetts); Henry M. Kronenberg (Belmont, Massachusetts) |
ABSTRACT | The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function. |
FILED | Thursday, August 28, 2008 |
APPL NO | 12/200419 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776336 | Grandi et al. |
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ASSIGNEE(S) | Novartis Vaccines and Diagnostics SRL (Siena, Italy) |
INVENTOR(S) | Guido Grandi (Segrate, Italy); John Telford (Monteriggioni, Italy); Renata Maria Grifantini (Siena, Italy) |
ABSTRACT | Disclosed are several Y. pestis antigens that are particularly suitable for immunisation purposes, particularly when used in combinations. |
FILED | Wednesday, October 25, 2006 |
APPL NO | 12/091604 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776338 | Connell et al. |
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ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Terry D. Connell (Williamsville, New York); Michael W. Russell (East Amherst, New York); Hesham Nawar (Buffalo, New York); Sergio Arce (Williamsville, New York) |
ABSTRACT | The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens. |
FILED | Wednesday, November 05, 2008 |
APPL NO | 12/265516 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776341 | Belisle et al. |
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ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); New York University (New York, New York) |
INVENTOR(S) | John T. Belisle (Fort Collins, Colorado); Mark J. Sartain (Fort Collins, Colorado); Suman Laal (Cortlandt Manor, New York) |
ABSTRACT | Mycobacterial proteins from culture filtrate or cytosol are disclosed as being useful B cell antigens for early diagnosis of mycobacterial disease, particularly in humans. These proteins include four that had not previously been recognized as B cell antigens (LppZ protein encoded by Mtb gene Rv3006; SodC protein encoded by Mtb gene Rv0432; BfrB protein encoded by Mtb gene Rv3841 and TrxC protein encoded by Mtb gene Rv3914). Antigenic compositions include these proteins and/or peptide fragments thereof, in various combinations with each other or with one or more of a set of 10 additional Mtb proteins known to be antigens (in particular early antigens. Methods and kits for using these antigenic composition for early diagnosis of mycobacterial infection and disease are also disclosed. |
FILED | Friday, August 10, 2007 |
APPL NO | 11/837264 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/248.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776344 | Hartmann et al. |
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ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); Coley Pharmaceutical GmbH (Dusseldorf, Germany); Coley Pharmaceutical Group, Inc. (New York, New York) |
INVENTOR(S) | Gunther Hartmann (Munich, Germany); Robert L. Bratzler (Concord, Massachusetts); Arthur M. Krieg (Wellesley, Massachusetts) |
ABSTRACT | Methods and compositions are provided for extending the clinical utility of IFN-α in the treatment of a variety of viral and proliferative disorders. Among other aspects, the invention provides methods which increase the efficacy of IFN-α treatment and reduce IFN-α treatment-related side effects. In addition, methods are provided for supporting the survival and for activating natural interferon producing cells (IPCs) in vitro without exogenous IL-3 or GM-CSF. The invention is based on the discovery that certain CpG and non-CpG ISNAs promote survival and stimulation of IPCs. |
FILED | Friday, July 08, 2005 |
APPL NO | 11/179008 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/278.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776361 | Ting |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Kang Ting (Beverly Hills, California) |
ABSTRACT | This invention pertains to the discovery that the human NELL-1 gene induces or upregulates bone mineralization. The NELL-1 gene or gene product thus provides a convenient target for screening for modulators of bone mineralization. In addition, NELL-1 can be used to facilitate repair of bone fractures and/or to generally increase bone density. |
FILED | Tuesday, March 28, 2006 |
APPL NO | 11/392294 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/549 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776518 | Altieri et al. |
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ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Dario C. Altieri (Worcester, Massachusetts); Robert M. Weiss (North Haven, Connecticut); Shannon D. Smith (Guilford, Connecticut); Victor A. Morris, legal representative (Guilford, Connecticut); Marcia A. Wheeler (Branford, Connecticut); Janet Plescia (Meriden, Connecticut) |
ABSTRACT | The present invention includes a method for diagnosing cancer and predicting recurrent cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing. |
FILED | Wednesday, June 18, 2003 |
APPL NO | 10/463867 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776520 | Fisher |
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ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | David E. Fisher (Newton, Massachusetts) |
ABSTRACT | Microphthalmia (Mi) while present in melanocytes, a cells and osteoclast, is not normally present in other cells. We have found that Mi is present in the nucleus of melanoma cells. Melanoma can be diagnosed by contacting a malignant cell with a probe for Mi. If the probe identifies Mi in the nucleus of the cell, the cell is a melanoma. |
FILED | Wednesday, November 24, 2004 |
APPL NO | 10/997018 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776521 | Rota et al. |
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ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
INVENTOR(S) | Paul A. Rota (Decatur, Georgia); Larry J. Anderson (Atlanta, Georgia); William J. Bellini (Lilburn, Georgia); Michael D. Bowen (Decatur, Georgia); Cara Carthel Burns (Avondale Estates, Georgia); Raymond Campagnoli (Decatur, Georgia); Qi Chen (Marietta, Georgia); James A. Comer (Decatur, Georgia); Byron T. Cook (Augusta, Georgia); Shannon L. Emery (Lusaka, Zambia); Dean D. Erdman (Decatur, Georgia); Cynthia S. Goldsmith (Lilburn, Georgia); Jeanette Guarner (Decatur, Georgia); Charles D. Humphrey (Lilburn, Georgia); Joseph P. Icenogle (Atlanta, Georgia); Thomas G. Ksiazek (Lilburn, Georgia); Richard F. Meyer (Roswell, Georgia); Stephan S. Monroe (Decatur, Georgia); William Allan Nix (Bethlehem, Georgia); M. Steven Oberste (Lilburn, Georgia); Christopher D. Paddock (Atlanta, Georgia); Teresa C. T. Peret (Atlanta, Georgia); Pierre E. Rollin (Lilburn, Georgia); Mark A. Pallansch (Lilburn, Georgia); Anthony Sanchez (Lilburn, Georgia); Wun-Ju Shieh (Norcross, Georgia); Suxiang Tong (Alpharetta, Georgia); Sherif R. Zaki (Atlanta, Georgia) |
ABSTRACT | Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use. |
FILED | Monday, May 14, 2007 |
APPL NO | 11/748359 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776527 | Hsu et al. |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Li-Chung Hsu (San Diego, California); Michael Karin (La Jolla, California) |
ABSTRACT | The present invention relates to microbial infection, and in particular, the reduction of apoptosis associated with microbial infection, the screening of agents that reduce apoptosis, and the treatment and analysis of microbial infection in vivo. In one embodiment, the present invention relates to agents including but not limited to reducing the activity of Protein Kinase R. |
FILED | Friday, November 12, 2004 |
APPL NO | 10/578976 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776528 | Lakowicz |
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ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Joseph R. Lakowicz (Ellicot City, Maryland) |
ABSTRACT | Compositions and methods for increasing the fluorescence intensity of molecules are provided. In particular, compositions and methods directed to increasing the intrinsic fluorescence of biomolecules and low quantum yield fluorophores are described. The intrinsic fluorescence of biomolecules is increased by positioning a metal particle and a biomolecule at a distance apart sufficient to increase the radiative decay rate of the biomolecule. Methods for the identification of nucleic acids are also provided. The compositions and methods can also be used to increase the emission of any fluorophore, such as the extrinsic probes used to label biomolecules. |
FILED | Thursday, November 18, 2004 |
APPL NO | 10/990549 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776531 | Black et al. |
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ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
INVENTOR(S) | Fiona E. Black (San Diego, California); Steven M. Barnard (San Diego, California); Nels A. Olson (San Diego, California) |
ABSTRACT | The present invention provides a method for detecting a target analyte by providing a substrate having attached polynucleotides and a stabilization polymer layer; removing the stabilization polymer layer; contacting the substrate with a target analyte; and detecting the target analyte. |
FILED | Friday, January 27, 2006 |
APPL NO | 11/341115 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776533 | Agnew et al. |
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ASSIGNEE(S) | Life Technologies Corporation (Carlsbad, California) |
INVENTOR(S) | Brian Agnew (Eugene, Oregon); Joseph Beechem (Eugene, Oregon); Kyle R Gee (Springfield, Oregon); Richard P Haugland (Olympia, Washington); Thomas H Steinberg (Eugene, Oregon); Wayne F Patton (Newton, Massachusetts) |
ABSTRACT | The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target molecules that interact with phosphorylated target molecules or molecules capable of being phosphorylated. A binding solution is provide that comprises a phosphate-binding compound, an acid and a metal ion wherein the metal ion simultaneously interacts with an exposed phosphate group on a target molecule and the metal chelating moiety of the phosphate-binding compound forming a bridge between the phosphate-binding compound and a phosphorylated target molecule resulting in a ternary complex. The binding solution of the present invention finds use in binding and detecting immobilized and solubilized phosphorylated target molecules, isolation of phosphorylated target molecules from a complex mixture and aiding in proteomic analysis wherein kinase and phosphatase substrates and enzymes can be identified. |
FILED | Tuesday, October 24, 2006 |
APPL NO | 11/552275 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776536 | Pinkel et al. |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Daniel Pinkel (Walnut Creek, California); Donna Albertson (Cambridge, United Kingdom); Joe W. Gray (San Francisco, California) |
ABSTRACT | The present invention provides methods of determining relative copy number of target nucleic acids and precise mapping of chromosomal abnormalities associated with disease. The methods of the invention use target nucleic acids immobilized on a solid surface, to which a sample comprising two sets of differentially labeled nucleic acids are hybridized. The hybridization of the labeled nucleic acids to the solid surface is then detected using standard techniques. |
FILED | Thursday, March 29, 2007 |
APPL NO | 11/727935 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776541 | Polyak et al. |
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ASSIGNEE(S) | Dana-Faber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Kornelia Polyak (Brookline, Massachusetts); Charlotta Enerback (Gothenburg, Sweden) |
ABSTRACT | The invention features methods of diagnosing high grade ductal carcinoma in situ (DCIS) These methods involve measuring: (1) the level of HID-5 in a body fluid (e.g., blood or urine) of a subject suspected of having, or at risk of having, high grade DCIS; or (2) the level of HID-5 gene expression in breast tissue from a subject suspected of having, or at risk of having, high grade DCIS. The invention also embodies a method of inhibiting expression of HID-5 protein in DCIS cells and methods of treating a subject suspected of having, or at risk of having, high grade DCIS. |
FILED | Monday, December 08, 2008 |
APPL NO | 12/330342 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776550 | Block et al. |
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ASSIGNEE(S) | Philadelphia Health and Education Corporation (Philadelphia, Pennsylvania) |
INVENTOR(S) | Timothy M. Block (Doylestown, Pennsylvania); Mary Ann Comunale (Bangor, Pennsylvania); Anand Mehta (Lansdale, Pennsylvania) |
ABSTRACT | Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting glycosylation, and more specifically fucosylation, on proteins in biological fluids, and comparing the detected glycosylation with reference values for the glycosylation of such proteins in healthy or disease states. |
FILED | Friday, May 05, 2006 |
APPL NO | 11/418598 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776553 | Love et al. |
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ASSIGNEE(S) | Presidents and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | J. Christopher Love (Cambridge, Massachusetts); Hidde L. Ploegh (Brookline, Massachusetts); Jehnna Ronan (Chester, New Hampshire) |
ABSTRACT | Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with each other. In some examples, the assays and methods may be used to determine if a known antigen binds to an unknown monoclonal antibody. |
FILED | Monday, September 18, 2006 |
APPL NO | 11/523124 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776563 | Hazen et al. |
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ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Stanley L. Hazen (Pepper Pike, Ohio); Marc S. Penn (Beachwood, Ohio) |
ABSTRACT | The present invention provides methods and agents for treating subjects who have or are at risk of developing or having cardiovascular disease. Such agents inhibit binding of myeloperoxidase (MPO) to a molecule comprising the MPO binding site of apolipoprotein A-1 (apoA-1) and include a peptide fragment of apoA-1 comprising at least 4 contiguous amino acids in SEQ ID. NO: 2, a modified form of the apo-1 fragment comprising one or more D amino acids, a retro-inverso form of the apoA-1 peptide fragment, an organo-mimetic of the apoA-1 peptide fragment, a peptide-mimetic of the apoA1 peptide fragment, or a nucleic acid encoding the apo A-1 peptide fragment. The present invention also provides methods of identifying or screening test agents for treating subjects having or at risk of having or developing CVD. The method comprises incubating one or more test agents and MPO with a molecule comprising the MPO binding site of apoA-1 under conditions which permit binding of MPO to the MPO binding site and determining whether one or more of the agents inhibit such binding. |
FILED | Friday, May 23, 2008 |
APPL NO | 12/126109 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776565 | Betenbaugh et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland); Human Genome Sciences, Inc. (Rockville, Maryland) |
INVENTOR(S) | Michael J. Betenbaugh (Baltimore, Maryland); Shawn Lawrence (Dobbs Ferry, New York); Yuan C. Lee (Timonium, Maryland); Timothy A. Coleman (Gaithersburg, Maryland) |
ABSTRACT | Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins. |
FILED | Friday, February 27, 2009 |
APPL NO | 12/394479 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/84 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776591 | Xia et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
INVENTOR(S) | Lijun Xia (Edmond, Oklahoma); Rodger P. McEver (Oklahoma City, Oklahoma) |
ABSTRACT | A method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method, an effective amount of an α1,3-fucosyltransferase, e.g., α1,3-fucosyltransferase VI, is used in vitro to treat cord blood-derived hematopoietic stem cells to convert non-functional PSGL-1 or other ligands on the cell surface into functional forms that bind selectins, especially P-selectin or E-selectin. The treated cells have enhanced effectiveness in reconstituting bone marrow in patients in need of such therapy. |
FILED | Wednesday, June 07, 2006 |
APPL NO | 11/448359 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/366 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776593 | Levine et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Fred Levine (Del Mar, California); Bjoern Tyrberg (San Diego, California) |
ABSTRACT | The present invention provides methods of identifying endocrine stem and progenitor cells. |
FILED | Tuesday, August 07, 2007 |
APPL NO | 11/835391 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/370 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776596 | Badylak |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Stephen F. Badylak (West Lafayette, Indiana) |
ABSTRACT | A tissue graft construct for use in repairing diseased or damaged tissues is provided. The tissue graft construct comprises a matrix composition selected from the group consisting of urinary bladder submucosa and stomach submucosa, and extracts and hydrolysates thereof, added endothelial cells, and at least one additional preselected, exogenous population of cells which enhance initiation of the formation vessel-like structures in the graft construct. The preselected population of cells can be a population of non-keratinized or keratinized epithelial cells or a population of mesodermally-derived cells selected from the group consisting of fibroblasts, smooth muscle cells, skeletal muscle cells, cardiac muscle cells, multi-potential progenitor cells, pericytes, osteogenic cells, and any other suitable cell type, preferably selected based on the tissue to be repaired. Methods for enhancing the vascularization in vivo of these tissue graft constructs and for preparing these graft constructs are also provided. |
FILED | Friday, May 02, 2003 |
APPL NO | 10/428358 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776600 | Kumta et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Charles Sfeir (Pittsburgh, Pennsylvania); Jeffrey Owen Hollinger (Pittsburgh, Pennsylvania); Daiwon Chol (Pittsburgh, Pennsylvania); Lee Weiss (Pittsburgh, Pennsylvania); Phil Campbell (Cranberry Township, Pennsylvania) |
ABSTRACT | Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications. |
FILED | Wednesday, June 13, 2007 |
APPL NO | 11/811992 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776607 | Gladyshev et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Vadim N. Gladyshev (Lincoln, Nebraska); Dolph L. Hatfield (Washington, District of Columbia); Kuan-Teh Jeang (Rockville, Maryland); Alan Diamond (Naperville, Illinois); John C. Wootton (Rockville, Maryland) |
ABSTRACT | A 15 kDa selenium-containing protein (“selenoprotein”) is disclosed. The protein is shown to be differentially expressed in cancer cells, such as prostate cancer cells. There is a correlation between the presence of a polymorphism at nucleotide positions 811 and 1125 of the 15 kDa selenoprotein gene, and the presence of cancer. This polymorphism is more prevalent in the African American population. The determination of an individual's genotype may be used as an indicator of the need for dietary selenium supplementation to inhibit tumor development. Compositions including the isolated protein, specific binding agents that recognize the protein, as well as underlying nucleic acid sequences are presented, as are methods of using such compositions. |
FILED | Monday, September 22, 2008 |
APPL NO | 12/234968 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/64 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776613 | Zhuang et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Xiaowei Zhuang (Cambridge, Massachusetts); Wilfred Mark Bates (Somerville, Massachusetts); Michael J. Rust (Medford, Massachusetts) |
ABSTRACT | The present invention generally relates to sub-diffraction image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA or a protein. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction image resolution, computer programs and techniques for sub-diffraction image resolution, methods for promoting sub-diffraction image resolution, methods for producing photoswitchable entities, and the like. |
FILED | Wednesday, November 29, 2006 |
APPL NO | 11/605842 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776817 | Ford |
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APPLICANT(S) | |
ASSIGNEE(S) | Morehouse School of Medicine (Atlanta, Georgia) |
INVENTOR(S) | Byron Ford (Atlanta, Georgia) |
ABSTRACT | Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke, inflammation or organophosphate neurotoxins. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain. |
FILED | Friday, September 01, 2006 |
APPL NO | 11/514352 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776823 | Gallo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Richard L. Gallo (San Diego, California); Masamoto Murakami (Hokkaido, Japan) |
ABSTRACT | Provided are peptide and peptide consensus sequences, which inhibit bacterial growth and/or viral growth and mimic the activity of LL-37, CRAMP, and/or FALL-39. The peptides are useful as antimicrobials, anti-inflammatories and antiviral agents. |
FILED | Wednesday, October 20, 2004 |
APPL NO | 10/575537 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776824 | Barasch et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Columbia University (New York, New York); Children's Hospital Medical Center (Cincincati, Ohio) |
INVENTOR(S) | Jonathan M. Barasch (New York, New York); Prasad Devarajan (Cincinnati, Ohio); Kiyoshi Mori (New York, New York) |
ABSTRACT | Use of neutrophil gelatinase-associated lipocalin (NGAL) as a therapeutic and in a method of treating, reducing, or ameliorating an injury selected from an ischemic injury, an ischemic-reperfusion injury, and a toxin-induced injury, to an organ in a patient. The invention includes administering to the patient NGAL in an amount effective to treat, reduce or ameliorate ischemic, ischemic-reperfusion, or toxin-induced injury to the organ, such as the kidney. A siderophore can be co-administered with the NGAL. The invention also relates to administering a sideophore to enhance a response to secretion of NGAL following an ischemic or toxin-induced injury to an organ in a patient. |
FILED | Friday, May 06, 2005 |
APPL NO | 11/123364 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776826 | Vignery et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Unigene Laboratories, Inc. (Boonton, New Jersey); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Agnes Vignery (Branford, Connecticut); Nozer M. Mehta (Randolph, New Jersey); James P. Gilligan (Union, New Jersey) |
ABSTRACT | A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided. |
FILED | Monday, March 31, 2008 |
APPL NO | 12/059662 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776836 | Sullenger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Christopher P. Rusconi (Durham, North Carolina); Rebekah R. White (Durham, North Carolina) |
ABSTRACT | RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed. |
FILED | Friday, October 26, 2007 |
APPL NO | 11/925648 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776837 | Sullenger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Christopher P. Rusconi (Durham, North Carolina) |
ABSTRACT | RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed. |
FILED | Tuesday, November 06, 2007 |
APPL NO | 11/936015 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776877 | Charvat et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | ChemoCentryx, Inc. (Mountain View, California) |
INVENTOR(S) | Trevor T. Charvat (San Jose, California); Cheng Hu (Menlo Park, California); Anita Melikian (San Francisco, California); Aaron Novack (San Jose, California); Andrew M. K. Pennell (San Francisco, California); Edward J. Sullivan (San Jose, California); William D. Thomas (San Jose, California); Solomon Ungashe (Fremont, California); Penglie Zhang (Foster City, California); Jay Powers (Pacifica, California); Sreenivas Punna (Sunnyvale, California) |
ABSTRACT | Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists. |
FILED | Tuesday, June 17, 2008 |
APPL NO | 12/140593 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776883 | Di Santo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Roberto Di Santo (Rome, Italy); Yves Pommier (Bethesda, Maryland); Christophe Marchand (Bethesda, Maryland); Marino Artico (Rome, Italy); Roberta Costi (Rome, Italy) |
ABSTRACT | Novel quinoline inhibitors of retroviral integrase, particularly HIV-1 integrase. The quinoline inhibitors are oxoquinolines that can be used for preventing or treating AIDS or HIV infection in a subject. |
FILED | Wednesday, March 09, 2005 |
APPL NO | 10/591679 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/314 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776894 | Ronai et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Burnham Institute for Medical Research (La Jolla, California) |
INVENTOR(S) | Ze'ev A. Ronai (San Diego, California); Anindita Bhoumik (San Diego, California); Nicholas D. P. Cosford (San Diego, California); Russell Dahl (Carlsbad, California) |
ABSTRACT | There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provided derivatives of celastrol and compositions comprising acetyl isogambogic acid, celastrol, or a derivative thereof. |
FILED | Friday, August 15, 2008 |
APPL NO | 12/192753 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/357 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776908 | Powis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Arizona Board of Regents (Tucson, Arizona); The University of Pittsburgh (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Garth Powis (Houston, Texas); Peter Wipf (Pittsburgh, Pennsylvania) |
ABSTRACT | Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well, as tumor formation in a subject are described herein. |
FILED | Thursday, September 20, 2007 |
APPL NO | 11/858508 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/422 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776916 | Freeman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); University of Oregon (Eugene, Oregon) |
INVENTOR(S) | Bruce A. Freeman (Pittsburgh, Pennsylvania); Francisco Schopfer (Pittsburgh, Pennsylvania); Valerie O'Donnell (Penarth, United Kingdom); Paul Baker (Pittsburgh, Pennsylvania); Yuqing E. Chen (Ann Arbor, Michigan); Bruce Branchaud (Eugene, Oregon) |
ABSTRACT | Described herein are nitrated lipids and methods of making and using the nitrated lipids. |
FILED | Tuesday, April 26, 2005 |
APPL NO | 11/568377 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/558 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777000 | Gallo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Richard L. Gallo (San Diego, California); Donald Y. M. Leung (Denver, Colorado); James F. Jones (Decatur, Georgia) |
ABSTRACT | The disclosure provides methods and compositions useful in the treatment of dermatitis and viral infections. The compositions comprise cationic peptides of the cathelicidin family including LL-37, related homologues, and variants thereof. |
FILED | Friday, March 05, 2004 |
APPL NO | 10/546739 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777001 | Fasano et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Alessio Fasano (West Friendship, Maryland); Stefanie N. Vogel (Columbia, Maryland) |
ABSTRACT | Agonist polypeptide of a receptor protein has been identified. The agonist can be used to facilitate drug and antigen absorption. Suitable routes of administration include oral, nasal, transdermal, and intravenous. Pharmaceutical formulations may comprise a therapeutic agent or an immunogenic agent in combination with the agonist polypeptide. |
FILED | Friday, August 11, 2006 |
APPL NO | 11/502490 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/329 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777005 | Croce et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Carlo M Croce (Philadelphia, Pennsylvania); Hideshi Ishii (Bryn Mawr, Pennsylvania) |
ABSTRACT | The invention relates to isolated polynucleotides homologous with a portion of one strand of the human tumor suppressor gene, FEZ1, and to the tumor suppressor protein encoded thereby, Fez1. The polynucleotides are useful, for example, as probes, primers, portions of expression vectors, and the like. The invention also includes diagnostic, therapeutic, cell proliferation enhancement, and screening methods which involve these polynucleotides and protein. The invention further includes kits useful for performing the methods of the invention. |
FILED | Tuesday, November 21, 2006 |
APPL NO | 11/602656 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/352 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777016 | Okumoto et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia) |
INVENTOR(S) | Sakiko Okumoto (Washington, District of Columbia); Loren L. Looger (Washington, District of Columbia); Wolf B. Frommer (Washington, District of Columbia) |
ABSTRACT | Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture. |
FILED | Friday, October 14, 2005 |
APPL NO | 11/665343 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777019 | Pastan et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Ira Pastan (Potomac, Maryland); Giuliana Salvatore (Naples, Italy); Richard Beers (Rockville, Maryland); Robert J. Kreitman (Potomac, Maryland) |
ABSTRACT | Recombinant immunotoxins are fusion proteins composed of the Fv domains of antibodies fused to bacterial or plant toxins. RFB4 (Fv)-PE38 is an immunotoxin that targets CD22 expressed on B cells and B cell malignancies. The present invention provides antibodies and antibody fragments that have improved ability to bind the CD22 antigen of B cells and B cell malignancies compared to RFB4. Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells. Compositions that incorporate these antibodies into chimeric immunotoxin molecules that can be used in medicaments and methods for inhibiting the growth and proliferation of leukemia and lymphoma cells. |
FILED | Wednesday, February 13, 2008 |
APPL NO | 12/030828 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.530 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777025 | Schramm et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York); Industrial Research Limited (Lower Hutt, New Zealand) |
INVENTOR(S) | Vern L. Schramm (New Rochelle, New York); Richard Hubert Furneaux (Wellington, New Zealand); Peter Charles Tyler (Wellington, New Zealand); Gary Brian Evans (Lower Hutt, New Zealand) |
ABSTRACT | Improved transition state analog inhibitors of ricin toxin-A are provided. Methods of using those inhibitors to inhibit ricin toxin-A and to prevent the toxic effects of ricin toxin-A in a mammal are also provided. |
FILED | Thursday, September 09, 2004 |
APPL NO | 10/570673 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/27.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777029 | Grotjahn et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
INVENTOR(S) | Douglas Grotjahn (San Diego, California); Erik Wiener (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to a method for preparing a bifunctional chelator for lanthanide. The method comprises the steps of providing a starting material which has an amino and carboxyl group; protecting the amino with an amino protecting group and the carboxyl with a carboxyl protecting group to produce a protected compound; reacting the protected compound with cyclen to generate a monoalkylated cyclen; reacting the monoalkylated cyclone with an activated compound to generated tetra-alkylated cyclone; removing the amino protecting group with a first protecting group removal reagent; and removing the carboxyl protecting groups with a second protecting group removal reagent to yield a bifunctional chelator having three more carboxyl groups and one or more amino groups. |
FILED | Wednesday, May 02, 2007 |
APPL NO | 11/743654 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Organic compounds 540/474 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777392 | Chen et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Shih-Chi Chen (Boston, Massachusetts); Martin L. Culpepper (Danvers, Massachusetts) |
ABSTRACT | A thermomechanical actuation system and method includes an elongated thermomechanical actuator (TMA), which is contoured so that electrical resistance at a mid-portion of the TMA is less than at end portions thereof. A pulse generator is electrically coupled to the TMA, and is configured to supply excitation pulses to the TMA. The excitation pulses are transient, so that each pulse is terminated prior to reaching a steady state amplitude, while having sufficient energy to heat the TMA to its predetermined operational temperature range. |
FILED | Thursday, November 08, 2007 |
APPL NO | 11/937224 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/306 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777484 | Garwood et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
INVENTOR(S) | Michael Garwood (Medina, Minnesota); Djaudat S. Idiyatullin (Minneapolis, Minnesota); Curt Corum (Shoreview, Minnesota); Steen Moeller (Golden Valley, Minnesota) |
ABSTRACT | A method of magnetic resonance is provided that uses a frequency swept excitation wherein the acquired signal is a time domain signal is provided. In one embodiment, the method comprises, applying a sweeping frequency excitation and acquiring a time domain signal. The sweeping frequency excitation has a duration and is configured to sequentially excite isochromats having different resonant frequencies. Acquisition of the time domain signal is done during the duration of the sweeping frequency excitation. The time domain signal is based on evolution of the isochromats. |
FILED | Monday, September 15, 2008 |
APPL NO | 12/210342 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/307 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777486 | Hargreaves et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Brian Hargreaves (Menlo Park, California); Wenmiao Lu (Palo Alto, California) |
ABSTRACT | A method for magnetic resonance imaging (MRI) is provided. A magnetic resonance excitation is provided. A plurality of k-space echoes is acquired bi-directionally wherein at least one echo is an even echo acquired in a first direction and at least one echo is an odd echo acquired in a second direction opposite from the first direction. K-space echo realignment is corrected between the even and odd echoes. Field inhomogeneity induced artifacts are corrected. Chemical shift induced artifacts between at least two species are corrected. |
FILED | Thursday, September 13, 2007 |
APPL NO | 11/854687 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777487 | Ying et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
INVENTOR(S) | Lei Ying (Kenosha, Wisconsin); Jinhua Sheng (Chicago, Illinois) |
ABSTRACT | A method of parallel magnetic resonance imaging (pMRI) comprising acquiring pMRI signals simultaneously through a plurality of receiving coils, wherein each coil has a localized sensitivity with respect to an imaged volume; jointly estimating values for the imaged volume and for a sensitivity function for at least one of the plurality of receiving coils; and transmitting the reconstructed image to a device. |
FILED | Friday, February 15, 2008 |
APPL NO | 12/032155 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778386 | Yin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Schenectady, New York); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Zhye Yin (Schenectady, New York); Jed Douglas Pack (Glenville, New York); Bruno K. B. De Man (Clifton Park, New York); Norbert J. Pelc (Los Altos, California) |
ABSTRACT | Disclosed are embodiments of methods for reconstructing x-ray projection data (e.g., one or more sinograms) acquired using a multi-source, inverse-geometry computed tomography (“IGCT”) scanner. One embodiment of a first method processes an IGCT sinogram by rebinning first in “z” and then in “xy,” with feathering applied during the “xy” rebinning. This produces an equivalent of a multi-axial 3rd generation sinogram, which may be further processed using a parallel derivative and/or Hilbert transform. A TOM-window (with feathering) technique and a combines backprojection technique may also be applied to produce a reconstructed volume. An embodiment of a second method processes an IGCT sinogram using a parallel derivative and/or redundancy weighting. The second method may also use signum weighting, TOM-windowing (with feathering), backprojection, and a Hilbert Inversion to produce another reconstructed volume. |
FILED | Friday, April 27, 2007 |
APPL NO | 11/741359 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778691 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Tiezhi Zhang (Madison, Wisconsin); Bhudatt R. Paliwal (Madison, Wisconsin) |
ABSTRACT | Radiation treatment of the lung or surrounding tissue during continuous breathing is made possible by preparing a treatment plan linked to motion phase and then synchronizing the plan to motion phase as the patient follows a regular breathing schedule. |
FILED | Thursday, November 06, 2003 |
APPL NO | 10/702810 |
ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/427 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778693 | Barbour et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Randall L. Barbour (Glen Head, New York); Yaling Pei (Morris Plains, New Jersey) |
ABSTRACT | A time series of optical tomography data is obtained for a target tissue site in a human (or animal), using an optical wavelength, such as near infrared, at which hemoglobin is absorptive, to observe properties of the vasculature of the human. The data may be compared to baseline data of a corresponding tissue site, e.g., from a healthy human, or from another, corresponding tissue site of the human. For example, a suspected cancerous breast of a human may be compared to a known healthy breast to detect differences in the vasculature. Measures may be made of flow, oxygen supply/demand imbalance, and evidence of altered regulation of the peripheral effector mechanism. The function of the target tissue site may be analyzed, along with the coordinated interaction between multiple sites of the target system. A provocation may be administered to identify surrogate markers of an underlying state or process. |
FILED | Monday, April 07, 2003 |
APPL NO | 10/408510 |
ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/473 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 07774912 | Gordon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Touchstone Research Laboratory, Ltd. (Triadelphia, West Virginia) |
INVENTOR(S) | Brian L. Gordon (Wheeling, West Virginia); Gregg W. Wolfe (Wheeling, West Virginia) |
ABSTRACT | Metal matrix composites having open or closed channels extending longitudinal through the length of the composite as well as methods and apparatus for forming the same are described. The shaped metal matrix composites are made of continuous fiber reinforced metal matrix composite materials. They have an integrally formed, non-cast, metal matrix composite body portion where the walls have a substantially uniform distribution of continuous fibers in a matrix metal throughout the volume of the walls and have at least one channel extending through the body of the shaped metal matrix composite. |
FILED | Wednesday, November 24, 2004 |
APPL NO | 10/995279 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Metal working 029/419.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07774913 | Murdy et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Richard M. Murdy (Bedford, Indiana); John C. Simmons (Koleen, Indiana); James R. Blake (Washington, Indiana); Timothy L. Barrett (Solsberry, Indiana) |
ABSTRACT | A device for separating opposed ceramic elements from a metal base member, the device including a rigid body shaped complementarily to an inside surface of the base member and receivable therein. Opposed wedge members are mounted are in the body wall. The body includes a threaded interior surface. A bolt is included for threaded engagement with the interior surface and has a conically-shaped end. Each wedge member is engageable with one of the ceramic elements, such that upon inserting of the body in the base member and threaded movement of the bolt inward to the body, the end of the bolt engages the wedge members to urge the wedge members outward through a body wall to engage the ceramic elements to urge the ceramic elements apart and to separate from the base member. |
FILED | Friday, September 08, 2006 |
APPL NO | 11/518739 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/426.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07774920 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Tao Deng (Niskayuna, New York); Francisco Arias (Mason, Ohio); Rustem F. Ismagilov (Chicago, Illinois); Paul J. A. Kenis (Champaign, Illinois); George M. Whitesides (Newton, Massachusetts) |
ABSTRACT | A method of forming microstructures. An article including a metal atom precursor is disproportionally exposed to electromagnetic radiation in an amount and intensity sufficient to convert some of the precursor to elemental metal. Additional conductive material may then be deposited onto the elemental metal to produce a microstructure. |
FILED | Wednesday, April 25, 2007 |
APPL NO | 11/789622 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/527.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775053 | Joe et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | Christopher R. Joe (Wethersfield, Connecticut); Paul M. Lutjen (Kennebunkport, Maine) |
ABSTRACT | A compact heat exchanger pedestal array for augmenting heat transfer in a machine is disclosed. The compact heat exchanger pedestal array includes a wall having first and second surfaces. The first surface faces a heated flow path and the second surface partially forms a flow path for cooling fluid. A plurality of pedestals extend from the second surface of the wall. At least one turbulator strip extends between adjacent pedestals. The turbulator strips and pedestals are operable for mixing the cooling fluid to increase heat transfer from the wall to the cooling fluid. |
FILED | Monday, September 20, 2004 |
APPL NO | 10/945477 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Power plants 060/806 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775146 | Bitar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xtreme ADS Limited (Anderson, Indiana) |
INVENTOR(S) | Peter Victor Bitar (Anderson, Indiana); Ricky Lee Busby (Anderson, Indiana); Leroy Ernest Lakey (Anderson, Indiana); Varce Eron Howe (Zionsville, Indiana) |
ABSTRACT | Disclosed is a system and method for neutralizing explosives and electronics utilizing a high voltage electrical discharge. |
FILED | Tuesday, February 12, 2008 |
APPL NO | 12/030144 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/1.130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775174 | Humphreys et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Vehicle Control Technologies, Inc. (Reston, Virginia) |
INVENTOR(S) | Douglas E. Humphreys (Great Falls, Virginia); Ryan D. Schulz (Reston, Virginia); Alexander V. Roup (Sterling, Virginia); Neill S. Smith (Springfield, Virginia); Daniel N. Dietz (Alexandria, Virginia) |
ABSTRACT | An at least partially self-propelled vehicle is configured for being towed by a towing vehicle, by way of a tow line. Operation of the vehicles may be coordinated so that, for a length of the tow line that connects the vehicles, the length of the tow line is curved in a manner that inhibits the tow line from transferring oscillatory motion between the vehicles while the entirety of the length of the tow line may be under tension. |
FILED | Friday, August 29, 2008 |
APPL NO | 12/231238 |
ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ships 114/244 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775770 | Carbaugh |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Steven R. Carbaugh (Glen Mills, Pennsylvania) |
ABSTRACT | A flexible, resilient seal protects a bearing in a pitch joint of a helicopter blade assembly from contaminants. The seal includes a flexible, resilient body having a first end bonded to a stationary portion of the joint, and a second end biased into sealing engagement with a displaceable portion of the joint. The body includes an intermediate bellows section surrounding the bearing that expands and contracts to accommodate displacement between the stationary and movable portions of the joint. The second end of the seal includes a lip that rubs on a sacrificial wear layer formed on the second portion of the joint. |
FILED | Thursday, December 21, 2006 |
APPL NO | 11/643318 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Fluid reaction surfaces 416/155 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775833 | Le et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Williams Pyro, Inc. (Fort Worth, Texas) |
INVENTOR(S) | Kevin D. Le (Richland Hills, Texas); Ricardo Ramirez (Fort Worth, Texas); Kisoo Jung (Irving, Texas) |
ABSTRACT | The high speed intelligent cable provided herein is multifunctional, lightweight, flexible and re-configurable. The cable assembly includes a low profile ribbon cable of multiple conductors. Built-in health indicators provide user assessment of, for example, connectivity. Active electronics and embedded intelligent firmware provide various functions, to include built-in test performance capability. Ready cable reconfiguration for system integration, or for other needs, is facilitated by logic and switching circuitry. Still further, built-in automatic multi-functional cable testing may include automatic reconfiguration. Testing and reconfiguration can be remotely activated. The cable described herein can reduce time and manhours needed for testing, installation, and maintenance. The lightweight multi-functional cable makes a positive contribution to the function/mass payload ratio in complex and mass-sensitive applications. |
FILED | Friday, June 27, 2008 |
APPL NO | 12/163507 |
ART UNIT | 2833 — Electrical Circuits and Systems |
CURRENT CPC | Electrical connectors 439/620.80 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776021 | Borenstein et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Charles Stark Draper Laboratory (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Jeffrey T. Borenstein (Holliston, Massachusetts); Eli Weinberg (Needham, Massachusetts); Brian K. Orrick (Cambridge, Massachusetts); Eleanor M. Pritchard (Cambridge, Massachusetts); Edward J. Barnard (Cambridge, Massachusetts); Nicholas J. Krebs (Boston, Massachusetts); Theodore Marentis (Boston, Massachusetts); Joseph P. Vacanti (Boston, Massachusetts); Mohammad Reza Kaazempur-Mofrad (Cambridge, Massachusetts) |
ABSTRACT | Methods and materials for making an apparatus which duplicates the functionality of a physiological system id provided. |
FILED | Friday, November 05, 2004 |
APPL NO | 10/983213 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Surgery 64/406 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776130 | Mirkin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Can Xue (Evanston, Illinois) |
ABSTRACT | Silver nanoprisms having a unimodal size distribution are disclosed. The size of the nanoprisms can be controlled by adjusting the pH during irradiation of silver nanocrystals. |
FILED | Monday, June 18, 2007 |
APPL NO | 11/820087 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/345 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776153 | Schowalter et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
INVENTOR(S) | Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (East Setauket, New York) |
ABSTRACT | A method and apparatus for producing bulk single crystals of AlN having low dislocation densities of about 10,000 cm−2 or less includes a crystal growth enclosure with Al and N2 source material therein, capable of forming bulk crystals. The apparatus maintains the N2 partial pressure at greater than stoichiometric pressure relative to the Al within the crystal growth enclosure, while maintaining the total vapor pressure in the crystal growth enclosure at super-atmospheric pressure. At least one nucleation site is provided in the crystal growth enclosure, and provision is made for cooling the nucleation site relative to other locations in the crystal growth enclosure. The Al and N2 vapor is then deposited to grow single crystalline low dislocation density AlN at the nucleation site. High efficiency ultraviolet light emitting diodes and ultraviolet laser diodes are fabricated on low defect density AlN substrates, which are cut from the low dislocation density AlN crystals. Bulk crystals of ZnO may also be produced using the method. |
FILED | Thursday, November 03, 2005 |
APPL NO | 11/265909 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/81 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776207 | Abhari et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Syntroleum Corporation (Tulsa, Oklahoma) |
INVENTOR(S) | Ramin Abhari (Bixby, Oklahoma); Paul Ahner (Tulsa, Oklahoma) |
ABSTRACT | A process for producing alkyl aromatic middle distillate fuels is described. The process includes (a) catalytically converting paraffinic naphtha to a composition containing benzene and olefins; (b) processing the olefin/benzene composition in an aromatic alkylation reactor to produce alkyl-benzene components (c) separating the alkyl aromatics from the unconverted naphtha; and (d) optionally recycling the unconverted paraffinic naphtha to the dehydrogenation/amortization reactor of step a. |
FILED | Friday, October 05, 2007 |
APPL NO | 11/868059 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Mineral oils: Processes and products 28/64 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776233 | Arafat et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | El Sayed Arafat (Leonardtown, Maryland); Judy Butler-Kowalik (Hollywood, Maryland); Kenneth Clark (Chalfont, Pennsylvania); David L. Gauntt (Chestertown, Maryland) |
ABSTRACT | The invention relates to an oleaginous corrosion-inhibiting composition, and the use of said composition to protect metal from corrosion. The composition comprises, in parts by weight, from about 20 to 60 parts of lubricating oil, 10 to 40 parts of organic solvent, 20 to 60 parts of corrosion-inhibitor consisting of a sulfonic acid-carboxylic acid metal complex or a mixture of said metal complex with a small but effective amount of an oil soluble alkyl phosphate, from 0.1 to 2.0 parts of an oil soluble antioxidant, from 0.1 to 5.0 parts of a water-displacing compound and from 0.0 to 1.0 part of a metal deactivator. |
FILED | Thursday, October 27, 2005 |
APPL NO | 11/264336 |
ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Compositions 252/395 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776235 | Marks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Milko E. van der Boom (Evanston, Illinois) |
ABSTRACT | The preparation of robust, thin film materials with large second-order optical nonlinearities through the covalent self-assembly of chromophoric compositions and innovative use of silyl chemistry. |
FILED | Tuesday, January 13, 2009 |
APPL NO | 12/352792 |
ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Compositions 252/582 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776269 | Snow et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Eric S. Snow (Springfield, Virginia); F. Keith Perkins (Alexandria, Virginia); Eric Houser (Nokesville, Virginia); Stan V. Stepnowski (Alexandria, Virginia); R. Andrew McGill (Lorton, Virginia) |
ABSTRACT | A sensing device having: a bottom electrode, a dielectric on the bottom electrode, a grid of nanoelectrodes on the dielectric, and a top electrode in electrical contact with the grid. A method of chemical or biological sensing comprising: providing a grid of nanoelectrodes; exposing the grid to fluid suspected of containing a chemical or biological analyte; and measuring a change in the capacitance and conductance of the grid. |
FILED | Tuesday, September 27, 2005 |
APPL NO | 11/239430 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776303 | Hung et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
INVENTOR(S) | Cheng-Hung Hung (Wexford, Pennsylvania); Noel R. Vanier (Wexford, Pennsylvania) |
ABSTRACT | The production of ultrafine metal carbide powders from polymeric powder and metallic precursor powder starting materials is disclosed. In certain embodiments, the polymeric powder may comprise polypropylene, polyethylene, polystyrene, polyester, polybutylene, nylon, polymethylpentene and the like. The metal precursor powder may comprise pure metals, metal alloys, intermetallics and/or metal-containing compounds such as metal oxides and nitrides. In one embodiment, the metal precursor powder comprises a silicon-containing material, and the ultrafine powders comprise SiC. The polymeric and metal precursor powders are fed together or separately to a plasma system where the feed materials react to form metal carbides in the form of ultrafine particles. |
FILED | Wednesday, August 30, 2006 |
APPL NO | 11/468430 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry of inorganic compounds 423/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776444 | Rinzler et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Andrew G. Rinzler (Newberry, Florida); Zhihong Chen (Gainesville, Florida) |
ABSTRACT | An optically transparent and electrically conductive single walled carbon nanotube (SWNT) film comprises a plurality of interpenetrated single walled carbon nanotubes, wherein for a 100 nm film the film has sufficient interpenetration to provide a 25° C. sheet resistance of less than 200 ohm/sq. The film also provides at least 20% optical transmission throughout a wavelength range from 0.4 μm to 5 μm. |
FILED | Thursday, October 19, 2006 |
APPL NO | 11/583545 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/408 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776548 | Rajasekaran |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ayyappan K. Rajasekaran (Los Angeles, California) |
ABSTRACT | A chimeric transmembrane protein comprising a membrane-spanning polypeptide and an internalization motif of the sequence MXXXL, where X is any amino acid. The chimeric protein can be expressed on the surface of a cell and internalized. Polynucleotides and expression vectors encoding chimeric transmembrane proteins are also provided. Expression of chimeric proteins in the plasma membrane of target cells, followed by binding of antibodies to the chimeric proteins, where the antibodies are conjugated to a cytotoxic agent, provides a means to deliver the cytotoxic agent to the inside of the target cells. |
FILED | Friday, September 30, 2005 |
APPL NO | 11/241416 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776600 | Kumta et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Charles Sfeir (Pittsburgh, Pennsylvania); Jeffrey Owen Hollinger (Pittsburgh, Pennsylvania); Daiwon Chol (Pittsburgh, Pennsylvania); Lee Weiss (Pittsburgh, Pennsylvania); Phil Campbell (Cranberry Township, Pennsylvania) |
ABSTRACT | Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications. |
FILED | Wednesday, June 13, 2007 |
APPL NO | 11/811992 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776613 | Zhuang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Xiaowei Zhuang (Cambridge, Massachusetts); Wilfred Mark Bates (Somerville, Massachusetts); Michael J. Rust (Medford, Massachusetts) |
ABSTRACT | The present invention generally relates to sub-diffraction image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA or a protein. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction image resolution, computer programs and techniques for sub-diffraction image resolution, methods for promoting sub-diffraction image resolution, methods for producing photoswitchable entities, and the like. |
FILED | Wednesday, November 29, 2006 |
APPL NO | 11/605842 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776642 | Eriksson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Mark A. Eriksson (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Arnold Melvin Kiefer (Madison, Wisconsin) |
ABSTRACT | A quantum-well photoelectric device, such as a quantum cascade laser, is constructed of monocrystalline nanoscale membranes physically removed from a substrate and mechanically assembled into a stack. |
FILED | Thursday, May 15, 2008 |
APPL NO | 12/120933 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/74 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776661 | Qin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Hua Qin (Madison, Wisconsin); Hyun Seok Kim (Madison, Wisconsin); Robert H. Blick (Madison, Wisconsin) |
ABSTRACT | A co-planar waveguide structure is integrated with an upwardly extending resonant pillar to produce transfer cells that provide controlled transmission of electricity between adjacent structures of the co-planar waveguide in order to produce easily fabricated electronic devices operating at megahertz and gigahertz speeds for filtration, modulation, rectification, and mixing of high-frequency signals. |
FILED | Wednesday, July 11, 2007 |
APPL NO | 11/776254 |
ART UNIT | 2813 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/144 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777180 | Hill, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Washington State University Research Foundation (Pullman, Washington) |
INVENTOR(S) | Herbert Henderson Hill, Jr. (Pullman, Washington); Maggie Tam (Pullman, Washington) |
ABSTRACT | The invention includes an ion mobility spectrometer having a liquid filled drift chamber. The chamber has an ionization region partitioned from and an ion separation region by a reversible ion-migration block. An electrical field within the chamber allows ions to migrate toward the electrode collector. Passage of ions from the ionization region is triggered by reversing the block allowing ions to migrate into the ion separation region. The invention includes a method of ion mobility analysis in liquid phase. Ions are mobilized to migrate through a drift liquid and are detected at an end of a drift chamber. The invention also includes a method of generating ions in a sample. A sample containing molecules in a first solvent is introduced into a second solvent through a charged capillary where the electrically charged sample is electro-disperses to ionize the molecules. |
FILED | Tuesday, July 15, 2008 |
APPL NO | 12/173750 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/286 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777188 | Fest et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Eric Fest (Tucson, Arizona); Rex Kremer (Tucson, Arizona) |
ABSTRACT | The disclosed system and apparatus for a sensor support structure generally includes a substantially reflective support strut having discontinuous protrusions on the support surface presented to the field of view of the sensor. These discontinuous protrusions may be suitably configured such that ambient thermal radiation is generally reflected away from the support strut and divergent from acceptance in the sensor's optical train. |
FILED | Tuesday, February 27, 2007 |
APPL NO | 11/679490 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/353 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777217 | Preble et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Kyma Technologies, Inc. (Raleigh, North Carolina) |
INVENTOR(S) | Edward A. Preble (Raleigh, North Carolina); Denis Tsvetkov (Morrisville, North Carolina); Andrew D. Hanser (Raleigh, North Carolina); N. Mark Williams (Raleigh, North Carolina); Xueping Xu (Stamford, Connecticut) |
ABSTRACT | In a method for making an inclusion-free uniformly semi-insulating GaN crystal, an epitaxial nitride layer is deposited on a substrate. A 3D nucleation GaN layer is grown on the epitaxial nitride layer by HVPE under a substantially 3D growth mode, wherein a surface of the nucleation layer is substantially covered with pits and the aspect ratio of the pits is essentially the same. A GaN transitional layer is grown on the nucleation layer by HVPE under a condition that changes the growth mode from the substantially 3D growth mode to a substantially 2D growth mode. After growing the transitional layer, a surface of the transitional layer is substantially pit-free. A bulk GaN layer is grown on the transitional layer by HVPE. After growing the bulk layer, a surface of the bulk layer is smooth and substantially pit-free. The GaN is doped with a transition metal during at least one of the foregoing GaN growth steps. |
FILED | Thursday, November 30, 2006 |
APPL NO | 11/606633 |
ART UNIT | 2823 — Optics |
CURRENT CPC | Active solid-state devices 257/21 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777241 | Moustakas et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Boston University (Boston, Massachusetts) |
INVENTOR(S) | Theodore D. Moustakas (Dover, Massachusetts); Jasper S. Cabalu (Allston, Massachusetts) |
ABSTRACT | A semiconductor sensor, solar cell or emitter or a precursor therefore having a substrate and textured semiconductor layer deposited onto the substrate. The layer can be textured as grown on the substrate or textured by replicating a textured substrate surface. The substrate or first layer is then a template for growing and texturing other semiconductor layers from the device. The textured layers are replicated to the surface from the substrate to enhance light extraction or light absorption. Multiple quantum wells, comprising several barrier and quantum well layers, are deposited as alternating textured layers. The texturing in the region of the quantum well layers greatly enhances internal quantum efficiency if the semiconductor is polar and the quantum wells are grown along the polar direction. This is the case in nitride semiconductors grown along the polar [0001] or [000-1] directions. |
FILED | Friday, April 15, 2005 |
APPL NO | 11/107150 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/95 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777318 | Tornquist Hennig et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northrop Grumman Systems Corporation (Los Angeles, California) |
INVENTOR(S) | Kelly Jill Tornquist Hennig (Torrance, California); Patty Pei-Ling Chang-Chien (Redondo Beach, California); Xianglin Zeng (Monterey Park, California); Jeffrey Ming-Jer Yang (Cerritos, California) |
ABSTRACT | A wafer-level package that employs one or more integrated hydrogen getters within the wafer-level package on a substrate wafer or a cover wafer. The hydrogen getters are provided between and among the integrated circuits on the substrate wafer or the cover wafer, and are deposited during the integrated circuit fabrication process. In one non-limiting embodiment, the substrate wafer is a group III-V semiconductor material, and the hydrogen getter includes a titanium layer, a nickel layer, and a palladium layer. |
FILED | Tuesday, July 24, 2007 |
APPL NO | 11/782460 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/682 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777496 | Evans et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | James A. Evans (Tallulah, Louisiana); Joseph B. Dunbar (Vicksburg, Mississippi); George L. Mason (Vicksburg, Mississippi); Richard W. Haskins (Raymond, Mississippi) |
ABSTRACT | A system and associated method permit remote monitoring of subsurface structure for purposes of early detection and location of hidden anomalies, e.g., water seepage in levees. Anomalies may be due to sand boils or displacement of underlying soil. Representative systems provide continuous monitoring via two complementary means: parallel pairs of ported (leaky) coaxial cables and a fiber optic cable, each pair of coaxial cables associated with a fiber optic cable. A fiber optic system, with associated light source, processor and display, together with an RF system, provides data to a remote location via telemetry or cellular phone, or both. The fiber optic cable(s) allow monitoring of displacement and vibrations within the structure. The ported coaxial cables, with associated RF source, using the same processor, display and telemetry used with the fiber optic sub-system, provide data for monitoring moisture change correlated to changes in the dielectric constant of surrounding material. |
FILED | Friday, July 18, 2008 |
APPL NO | 12/175645 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/534 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777505 | White et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Henry S. White (Salt Lake City, Utah); Ryan J. White (Salt Lake City, Utah); Eric N. Ervin (Salt Lake City, Utah) |
ABSTRACT | A nanopore device includes a membrane having a nanopore extending there through forming a channel from a first side of the membrane to a second side of the membrane. The surface of the channel and first side of the membrane are modified with a hydrophobic coating. A first lipid monolayer is deposited on the first side of the membrane, and a second lipid monolayer is deposited on the second side of the membrane, wherein the hydrophobic coating causes spontaneous generation of a lipid bilayer across the nanopore orifice. Sensing entities, such as a protein ion channel, can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages, while resistance or current flow through the sensing entity can be measured electrically. |
FILED | Wednesday, May 02, 2007 |
APPL NO | 11/743472 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/693 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777535 | In et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Visarath In (Chula Vista, California); Patrick Longhini (San Diego, California); Yong (Andy) An Kho (Chula Vista, California); Joseph D. Neff (San Diego, California); Adi R. Bulsara (San Diego, California) |
ABSTRACT | In various embodiments, an apparatus for down-converting a first signal having a first frequency to a lower frequency is disclosed. The apparatus can include one or more arrays of N over-damped, bi-stable circuits unidirectionally-coupled from element to element. |
FILED | Thursday, May 22, 2008 |
APPL NO | 12/125397 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/117 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777667 | Rankin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Peter M. Rankin (Syracuse, New York); Zenn Zenon (Syracuse, New York) |
ABSTRACT | A radar target identification apparatus utilizing a pseudo-random digital code to modulate a target's return signal to include a two-dimensional range and cross range Doppler-coded return with a target's skin return and thereby identify friendly targets to the interrogating radar unit. |
FILED | Wednesday, December 05, 1979 |
APPL NO | 06/101401 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/45 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777877 | Walker et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Christopher I. Walker (Pasadena, California); Axel Scherer (Laguna Beach, California) |
ABSTRACT | The invention provides a high efficiency coupling structure for extracting illumination such as fluorescent radiation from a chemical reaction vessel such as a cuvette. The cuvette is provided with a mirrored surface. An end cap for the cuvette includes a probe portion that exhibits total internal reflection. Lenses are provided in various embodiments that improve the light collection and directing properties of the end cap. A fast optical system for free space coupling of optical radiation emanating from a chemical processing cuvette that uses the end cap as an element is also described. |
FILED | Monday, October 22, 2007 |
APPL NO | 11/876211 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/246 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777889 | Qiu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Tiequn Qiu (Glendale, Arizona); Steven J. Sanders (Scottsdale, Arizona); Sorin Mosor (Peoria, Arizona); Glen A. Sanders (Scottsdale, Arizona) |
ABSTRACT | A computer-implementable method of reducing bias instability in a fiber optic gyroscope includes receiving, with a computer, a first data set enabling the computer to generate a model of the gyroscope, including a light source, a photodetector, and a plurality of optical components and fiber sections coupling the light source to the photodetector, and a light signal to be propagated from the light source to the photodetector. The light signal has an associated wavelength spectrum. For each wavelength of the spectrum, the relative lightwave intensity reaching the photodetector is calculated. A signal-wave intensity and a spurious-wave intensity are determined from the calculated relative lightwave intensities. A scale factor is determined from the signal-wave intensity. The spurious-wave intensity is integrated over the wavelength spectrum of the light source to obtain a total spurious-wave intensity. A rate bias error is determined based on the total spurious-wave intensity and the scale factor. |
FILED | Thursday, August 07, 2008 |
APPL NO | 12/187932 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/460 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778111 | Hawkinson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Wesley J. Hawkinson (Chanhassen, Minnesota); Kevin Sweeney (Minneapolis, Minnesota); Randolph G. Hartman (Plymouth, Minnesota) |
ABSTRACT | A method for navigating underwater is disclosed. The method uses a navigation system to project a first velocity measurement along one or more signal beams having a second velocity measurement, where the second velocity measurement is related to at least one of the one or more signal beams. The method determines a position and location of an object associated with the navigation system based on a prediction of at least the second velocity measurement, and the navigation system is adjusted to perform within a prescribed measurement range based on a covariance of the first and second velocity measurements. The performance adjustments made in determining the position and location of the object are operable independent of the navigation system maintaining each of the signal beams due to one or more external environmental conditions. |
FILED | Wednesday, March 19, 2008 |
APPL NO | 12/051740 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/89 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778183 | Fan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Jinliang Fan (Redmond, Washington); Nagui Halim (Yorktown Heights, New York); Zhen Liu (Tarrytown, New York); Dimitrios Pendarakis (Westport, Connecticut) |
ABSTRACT | A method is provided for selecting a replication node from eligible nodes in a network. A multidimensional model is constructed that defines a multidimensional space and includes the eligible nodes, with each of the dimensions of the multidimensional model being a system characteristic. A data availability value is determined for each of the eligible nodes, and a cost of deploying is determined for each of at least two availability strategies to the eligible nodes. At least one of the eligible nodes is selected for replication of data that is stored on a source node in the network. The selecting step includes selecting the eligible node whose: data availability value is determined to be highest among the eligible nodes whose cost of deploying does not exceed a specified maximum, or cost of deploying is determined to be lowest among the eligible nodes whose data availability value does not exceed a specified minimum. |
FILED | Tuesday, February 20, 2007 |
APPL NO | 11/676631 |
ART UNIT | 2471 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/238 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778296 | Vuckovic et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Jelena Vuckovic (Palo Alto, California); Ilya Fushman (Palo Alto, California); Dirk Robert Englund (Stanford, California) |
ABSTRACT | Optical microcavity arrangements and approaches facilitate a variety of applications. According to an example embodiment of the present invention, an optical microcavity arrangement includes a microcrystal structure having a plurality of optical cavities therein to facilitate the control of light. Emitters such as colloidal quantum dots are optically coupled to the optical cavities by attaching or otherwise arranging a material, which includes the emitters, to the optical microcavity arrangement. In many applications, the emitters couple photons of a wavelength in a range of wavelengths selectively passed by the optical cavities, and are amenable to operation at relatively high temperatures (e.g., at about room temperature or higher), which is useful for a variety of applications. |
FILED | Friday, May 11, 2007 |
APPL NO | 11/747721 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/41 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778493 | Ho et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. (Rockville, Maryland) |
INVENTOR(S) | Vincent B. Ho (North Bethesda, Maryland); Micah D. Schmidt (San Antonio, Texas) |
ABSTRACT | Methods for improving spatial and/or temporal resolution of digital images and for improving image data transmission by a novel technique—back pixelation, which involves data processing and reconstruction of overlaid images from multiple acquisition or multiple sampling. The back pixelation technique may be used for image data acquisition and transmission; it may be applied prospectively or retrospectively. In particular, the methods of this invention may be used in reducing the pixel size of a two-dimensional image or the voxel size of a three dimensional image; producing a two- or three-dimensional image from a multiplicity of images acquired from an object which are capable of overlaying one another by an increment; producing and transmitting a two- or three-dimensional image by multiple acquisitions according to an acquisition matrix; or transmitting a two- or three-dimensional image by reducing or decomposing the image to a plurality of image data packets and transmitting the same. The multiple acquisitions may be arranged by a predetermined temporal schedule. These methods may be advantageously applied in medical imaging, movies and video games, teleimage, and any other areas that involve digital image acquisition, processing, and transmission. |
FILED | Thursday, October 09, 2003 |
APPL NO | 10/686194 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/299 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778547 | Menendez |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Telcordia Technologies, Inc. (Piscataway, New Jersey) |
INVENTOR(S) | Ronald Charles Menendez (Chatham, New Jersey) |
ABSTRACT | The invention is directed to code labeling in an optical network. The network includes a transmitting station operable to transmit an optical signal. The network also includes an encoder coupled to the transmitting station operable to label the optical signal composed of a group of codes. A receiving station operable to receive the labeled group of optical codes is also provided. The receiving station is operable to read the optical signal if the label of the received group of codes corresponds to the group of codes assigned to the receiving station. |
FILED | Thursday, June 01, 2006 |
APPL NO | 11/444764 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Optical communications 398/77 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778948 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | W. Lewis Johnson (Venice, California); Hannes Högni Vilhjálmsson (Reykjavik, Iceland) |
ABSTRACT | A character programming and control system and method for programming and controlling a virtual character during a social simulation, a character programming method for programming the actions of a virtual character, and a system and method for developing social skills of a user. |
FILED | Wednesday, October 18, 2006 |
APPL NO | 11/550757 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Artificial intelligence 76/45 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779013 | Chi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
INVENTOR(S) | Ed H. Chi (Palo Alto, California); William S. Liu (Cupertino, California) |
ABSTRACT | A system and method for determining a quantitative measure of search efficiency of related Web pages. An information goal is specified. A target Web page is identified within a plurality of Web pages. The information goal is searched via a search function in the Web pages to identify potential Web pages that include at least one hyperlink referencing and proximal cues relating to distal content included in another potential Web page. An activation network is formed. A directed graph is built, including nodes corresponding to the potential Web pages and arcs corresponding to the hyperlinks. A weight is assigned to each arc to represent a probability of traversal of the corresponding hyperlink based on a relatedness of keywords in the information goal to the proximal cues. A traversal through the activation network to the node corresponding to the target Web page is evaluated as a quantitative measure of search efficiency. |
FILED | Friday, November 04, 2005 |
APPL NO | 11/267004 |
ART UNIT | 2159 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/748 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779025 | Gunawardena et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jamila Gunawardena (Palo Alto, California); Jacques Reifman (New Market, Maryland) |
ABSTRACT | The present invention is directed to a system and method for providing researchers with a computer-assisted tool to evaluate, over a communications network, large electronic data sets stored on a remote server. The system allows the centralization of multiple data manipulation and analysis software modules co-located with the large data sets to reduce the amount of data from the data sets and software that has to be downloaded to a particular user's client computer. The system is designed to accommodate multiple researchers located at different geographic locations each of whom may have, with regard to the data, different scientific research objectives. |
FILED | Monday, December 12, 2005 |
APPL NO | 11/298606 |
ART UNIT | 2166 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779148 | Arimilli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Bernard C. Drerup (Austin, Texas); Jody B. Joyner (Austin, Texas); Jerry D. Lewis (Round Rock, Texas) |
ABSTRACT | A mechanism for performing dynamic request routing based on broadcast source request information is provided. Each processor chip in the system may use a synchronized heartbeat signal it generates to provide source request information to each of the other processor chips in the system. The source request information identifies the number of active source requests sent by the processor chip that originated the heartbeat signal. The source request information from each of the processor chips in the system may be used by the processor chips in determining optimal routing paths for data from a source processor chip to a destination processor chip. As a result, the congestion of data for processing at each of the processor chips along each possible routing path may be taken into account when selecting to which processor chip to forward data. |
FILED | Friday, February 01, 2008 |
APPL NO | 12/024553 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/235 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779298 | Challenger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | James R. Challenger (Garrison, New York); Louis R. Degenaro (White Plains, New York); James R. Giles (Yorktown Heights, New York); Gabriela Jacques Da Silva (Champaign, Illinois) |
ABSTRACT | A method is provided for the recovery of an instance of a job manager running on one of a plurality of nodes used to execute the processing elements associated with jobs that are executed within a cooperative data stream processing system. The states of the processing elements are checkpointed to a persistence mechanism in communication with the job manager. From the checkpointed processing element states, the state of each distributed job is determined and checkpointed. Processing element states are also checkpointed locally to the nodes one which the processing elements are running. Following a failure of the job manager, the job manager is reinstantiated on one of the nodes. The recovery instance of the job manger obtains state data for processing elements and jobs from the persistence mechanism and constructs an initial state for jobs and processing elements. These initial states are reconciled against the current states of the processing elements and adjustments are made accordingly. Once the job and processing element states are reconciled, the system is returned to normal operation. |
FILED | Monday, June 11, 2007 |
APPL NO | 11/761152 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779359 | Francis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Gregory S. Francis (West Lafayette, Indiana); Clarence E. Rash (Fort Rucker, Alabama); Matthew J. Reardon (Birmingham, Alabama) |
ABSTRACT | A method that includes but is not limited to accepting user input specifying a geometrical arrangement of two or more buttons on one or more displayed pages; accepting user input labeling at least two of the two or more buttons on the one or more displayed pages; accepting user input defining at least one interaction between the labeled at least two buttons; accepting user input specifying at least one constraint cost for the defined at least one interaction; and assigning the labels of the at least two buttons among the two or more buttons on one or more displayed pages such that the at least one constraint cost is substantially optimized. |
FILED | Friday, July 20, 2001 |
APPL NO | 09/910669 |
ART UNIT | 2173 — Graphical User Interface and Document Processing |
CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/762 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07774920 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Tao Deng (Niskayuna, New York); Francisco Arias (Mason, Ohio); Rustem F. Ismagilov (Chicago, Illinois); Paul J. A. Kenis (Champaign, Illinois); George M. Whitesides (Newton, Massachusetts) |
ABSTRACT | A method of forming microstructures. An article including a metal atom precursor is disproportionally exposed to electromagnetic radiation in an amount and intensity sufficient to convert some of the precursor to elemental metal. Additional conductive material may then be deposited onto the elemental metal to produce a microstructure. |
FILED | Wednesday, April 25, 2007 |
APPL NO | 11/789622 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/527.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07774929 | Jacobs |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Heiko O. Jacobs (Minneapolis, Minnesota) |
ABSTRACT | A method of self-assembly of components on a surface of a substrate includes obtaining a first component and a second component. The first component type is assembled onto the substrate by programming the surface. The second component type is assembled by reprogramming the surface. A third component, next to the first and second components, is assembled following the step of assembling the first and second components. The first, second, and third components are all different types of components. docking sites on the substrate can be used that contain alignment pedestals. One component delivery system employ a liquid-liquid interface to deliver and concentrate components with correct pre-orientation. |
FILED | Wednesday, March 14, 2007 |
APPL NO | 11/686137 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/825 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07774931 | Tai et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
INVENTOR(S) | Yu-Chong Tai (Pasadena, California); Damien C. Rodger (South Pasadena, California); Wen Li (East Lansing, California); Mark Humayun (Glendale, California); James D. Weiland (Valencia, California); Hossein Ameri (Galveston, Texas); Armand R. Tanguay, Jr. (Yorba Linda, California) |
ABSTRACT | Intraocular retinal prosthesis devices and methods for fabricating the same. A prosthesis device includes a cable region that connects an electrode array region with a power and data management region. The electrode array region includes one or more arrays of exposed electrodes, and the power and data management region includes various power and control elements. The power and data management elements, in one aspect, include an RF coil or coils and circuit arrangements and/or chips configured to provide drive signals to the electrodes via a cable and receive power and signals from the RF coil or coils. Each region includes elements fabricated on or in a single polymer layer during the same fabrication process. |
FILED | Friday, April 28, 2006 |
APPL NO | 11/414139 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/832 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07774951 | Hartmann et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
ABSTRACT | A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip. |
FILED | Wednesday, October 03, 2007 |
APPL NO | 11/906751 |
ART UNIT | 2841 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Geometrical instruments 033/552 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775087 | Espinosa et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Horacio D. Espinosa (Winnetka, Illinois); Nicolaie A. Moldovan (Glenview, Illinois) |
ABSTRACT | A method of forming a microchannel as well as a thin film structure including same is made by forming a first thin film on a side of a substrate, forming a fugitive second thin film on the first thin film such that the second thin film defines a precursor of the elongated microchannel and a plurality of extensions connected to and extending transversely relative to the precursor along a length thereof A third thin film is formed on the first thin film and the fugitive second thin film such that the second thin film resides between the first thin film and the third thin film. A respective access site is formed in a region of the third thin film residing on a respective extension and penetrating to the fugitive second thin film. The fugitive second thin film forming the precursor is selectively removed from between the first thin film and the third thin film using an etching medium introduced through the access sites, thereby forming the microchannel between the first thin film and the third thin film. The method preferably further includes forming a sealing layer on the third thin film in a manner to close off open access sites remaining after selective removal of the second thin film. |
FILED | Tuesday, September 05, 2006 |
APPL NO | 11/516039 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/105 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776130 | Mirkin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Can Xue (Evanston, Illinois) |
ABSTRACT | Silver nanoprisms having a unimodal size distribution are disclosed. The size of the nanoprisms can be controlled by adjusting the pH during irradiation of silver nanocrystals. |
FILED | Monday, June 18, 2007 |
APPL NO | 11/820087 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/345 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776235 | Marks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Milko E. van der Boom (Evanston, Illinois) |
ABSTRACT | The preparation of robust, thin film materials with large second-order optical nonlinearities through the covalent self-assembly of chromophoric compositions and innovative use of silyl chemistry. |
FILED | Tuesday, January 13, 2009 |
APPL NO | 12/352792 |
ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Compositions 252/582 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776545 | Khosla et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Chaitan Khosla (Palo Alto, California); Lu Shan (Houston, Texas) |
ABSTRACT | Detection of toxic gluten oligopeptides refractory to digestion and antibodies and T cells responsive thereto can be used to diagnose Celiac Sprue. |
FILED | Thursday, November 20, 2003 |
APPL NO | 10/531547 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776565 | Betenbaugh et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland); Human Genome Sciences, Inc. (Rockville, Maryland) |
INVENTOR(S) | Michael J. Betenbaugh (Baltimore, Maryland); Shawn Lawrence (Dobbs Ferry, New York); Yuan C. Lee (Timonium, Maryland); Timothy A. Coleman (Gaithersburg, Maryland) |
ABSTRACT | Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins. |
FILED | Friday, February 27, 2009 |
APPL NO | 12/394479 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/84 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776600 | Kumta et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Charles Sfeir (Pittsburgh, Pennsylvania); Jeffrey Owen Hollinger (Pittsburgh, Pennsylvania); Daiwon Chol (Pittsburgh, Pennsylvania); Lee Weiss (Pittsburgh, Pennsylvania); Phil Campbell (Cranberry Township, Pennsylvania) |
ABSTRACT | Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications. |
FILED | Wednesday, June 13, 2007 |
APPL NO | 11/811992 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776642 | Eriksson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Mark A. Eriksson (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Arnold Melvin Kiefer (Madison, Wisconsin) |
ABSTRACT | A quantum-well photoelectric device, such as a quantum cascade laser, is constructed of monocrystalline nanoscale membranes physically removed from a substrate and mechanically assembled into a stack. |
FILED | Thursday, May 15, 2008 |
APPL NO | 12/120933 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/74 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776815 | Vanderby et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Ray Vanderby (Madison, Wisconsin); Kelley Dwyer Grorud (Madison, Wisconsin) |
ABSTRACT | Disclosed are a method and a corresponding pharmaceutical composition for treating damaged ligaments. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of ligaments damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP). |
FILED | Wednesday, February 23, 2005 |
APPL NO | 11/063627 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776817 | Ford |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Morehouse School of Medicine (Atlanta, Georgia) |
INVENTOR(S) | Byron Ford (Atlanta, Georgia) |
ABSTRACT | Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke, inflammation or organophosphate neurotoxins. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain. |
FILED | Friday, September 01, 2006 |
APPL NO | 11/514352 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776927 | Chu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Liang-Yin Chu (Chengdu, China PRC); Ho Cheung Shum (Hong Kong, China PRC); Alberto Fernandez-Nieves (Atlanta, Georgia); Andrew S. Utada (Cambridge, Massachusetts); Enric Santanach Carreras (Cambridge, Massachusetts); David A. Weitz (Bolton, Massachusetts) |
ABSTRACT | The present invention generally relates to emulsions such as multiple emulsions, and to methods and apparatuses for making emulsions, and techniques for using the same. A multiple emulsion generally describes larger droplets that contain one or more smaller droplets therein which, in some cases, can contain even smaller droplets therein, etc. Emulsions, including multiple emulsions can be formed in certain embodiments with generally precise repeatability, and can be tailored to include any number of inner droplets, in any desired nesting arrangement, within a single outer droplet. In addition, in some aspects of the invention, one or more droplets may be controllably released from a surrounding droplet. |
FILED | Friday, March 28, 2008 |
APPL NO | 12/058628 |
ART UNIT | 1796 — Organic Chemistry |
CURRENT CPC | Colloid systems and wetting agents; subcombinations thereof; processes of 516/54 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776971 | Percec |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees Of The University Of Pennslyvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Virgil Percec (Philadelphia, Pennsylvania) |
ABSTRACT | The inventive subject matter relates to novel synthetic processes which use a multifunctional compound (the “TERMINI compound”) having a masked or protected functional group, wherein the TERMINI compound is capable of quantitatively and irreversibly interrupting a living polymerization or a chain organic reaction. After deprotection or demasking of the functional group of the TERMINI compound, the same living polymerization or organic reaction resumes with 100% efficiency, or a different living polymerization or organic reaction resumes with 100% chemoselectivity, respectively. Once incorporated into a growing molecule, the TERMINI compound generates a branching point upon resumption of the polymerization or reaction. |
FILED | Thursday, May 06, 2004 |
APPL NO | 10/555599 |
ART UNIT | 1796 — Organic Chemistry |
CURRENT CPC | Synthetic resins or natural rubbers 525/342 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777290 | Lagally et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Zhenqiang Ma (Middleton, Wisconsin) |
ABSTRACT | The present invention provides high-speed, high-efficiency PIN diodes for use in photodetector and CMOS imagers. The PIN diodes include a layer of intrinsic semiconducting material, such as intrinsic Ge or intrinsic GeSi, disposed between two tunneling barrier layers of silicon oxide. The two tunneling barrier layers are themselves disposed between a layer of n-type silicon and a layer of p-type silicon. |
FILED | Tuesday, June 13, 2006 |
APPL NO | 11/452135 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/458 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777392 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Shih-Chi Chen (Boston, Massachusetts); Martin L. Culpepper (Danvers, Massachusetts) |
ABSTRACT | A thermomechanical actuation system and method includes an elongated thermomechanical actuator (TMA), which is contoured so that electrical resistance at a mid-portion of the TMA is less than at end portions thereof. A pulse generator is electrically coupled to the TMA, and is configured to supply excitation pulses to the TMA. The excitation pulses are transient, so that each pulse is terminated prior to reaching a steady state amplitude, while having sufficient energy to heat the TMA to its predetermined operational temperature range. |
FILED | Thursday, November 08, 2007 |
APPL NO | 11/937224 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/306 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777487 | Ying et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
INVENTOR(S) | Lei Ying (Kenosha, Wisconsin); Jinhua Sheng (Chicago, Illinois) |
ABSTRACT | A method of parallel magnetic resonance imaging (pMRI) comprising acquiring pMRI signals simultaneously through a plurality of receiving coils, wherein each coil has a localized sensitivity with respect to an imaged volume; jointly estimating values for the imaged volume and for a sensitivity function for at least one of the plurality of receiving coils; and transmitting the reconstructed image to a device. |
FILED | Friday, February 15, 2008 |
APPL NO | 12/032155 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777505 | White et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Henry S. White (Salt Lake City, Utah); Ryan J. White (Salt Lake City, Utah); Eric N. Ervin (Salt Lake City, Utah) |
ABSTRACT | A nanopore device includes a membrane having a nanopore extending there through forming a channel from a first side of the membrane to a second side of the membrane. The surface of the channel and first side of the membrane are modified with a hydrophobic coating. A first lipid monolayer is deposited on the first side of the membrane, and a second lipid monolayer is deposited on the second side of the membrane, wherein the hydrophobic coating causes spontaneous generation of a lipid bilayer across the nanopore orifice. Sensing entities, such as a protein ion channel, can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages, while resistance or current flow through the sensing entity can be measured electrically. |
FILED | Wednesday, May 02, 2007 |
APPL NO | 11/743472 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/693 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778165 | Madhyastha et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Harsha V. Madhyastha (Seattle, Washington); Thomas Anderson (Seattle, Washington); Arvind Krishnamurthy (Seattle, Washington); Arun Venkataramani (Northampton, Massachusetts) |
ABSTRACT | Performance metrics between any two arbitrary end-hosts are predicted based upon previous measurements on the Internet between a plurality of geographically dispersed vantage points and clusters of end-hosts. Each cluster comprises end-hosts that are related based upon their IP address prefixes. In response to a central agent that stores the measured data for each of a plurality of predicted paths on the Internet, the vantage points use traceroute software to measure and periodically update performance metrics such as latency, bottleneck capacity, bandwidth, and packet loss rate for links comprising the predicted paths between the vantage points and one (or more) destination points associated with each cluster, and gather such data using distributed application systems. A user or client application can subsequently request predicted performance metrics for communication between specific end-hosts, based upon the previous measurement data. |
FILED | Thursday, November 08, 2007 |
APPL NO | 11/937223 |
ART UNIT | 2473 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/229 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778301 | El-Sayed et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Mostafa A. El-Sayed (Atlanta, Georgia); Wei Qian (Marietta, Georgia); Qusai Darugar (Houston, Texas) |
ABSTRACT | Disclosed is a lasing complex comprising a room temperature solution containing cadmium sulfide (CdS) quantum dots. Optical gain has been observed in CdS nanocrystal quantum dots in strong confinement regime in toluene solution at room temperature using femtosecond transient absorption techniques. The optical gain lifetime is measured to be 20 picoseconds under pump fluence of 0.77 mJ/cm2. The relative lower gain threshold compared to that of CdSe quantum dots is attributed to the long lifetime of fluorescence and biexcitons and the relatively sharp photoluminescence linewidth. The CdS nanocrystals are excellent gain media for semiconductor quantum dot based blue lasers. |
FILED | Wednesday, June 25, 2008 |
APPL NO | 12/215158 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/51 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778815 | Pasricha et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Sudeep Pasricha (Irvine, California); Nikil Dutt (Irvine, California); Mohamed Ben-Romdhane (Irvine, California) |
ABSTRACT | A computer system simulation method starts with algorithmically implementing a specification model independently of hardware architecture. High level functional blocks representing hardware components are connected together using a bus architecture-independent generic channel. The bus architecture-independent generic channel is annotated with timing and protocol details to define an interface between the bus architecture-independent generic channel and functional blocks representing hardware components. The interface is refined to obtain a CCATB for communication space. The read( ) and write( ) interface calls are decomposed into several method calls which correspond to bus pins to obtain observable cycle accuracy for system debugging and validation and to obtain a cycle accurate model. The method calls are replaced by signals, and the functional blocks representing hardware components are further refined to obtain pin/cycle-accurate models which can be manually or automatically mapped to RTL, or be used to co-simulate with existing RTL components. |
FILED | Thursday, May 26, 2005 |
APPL NO | 11/139370 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07778995 | Qamhiyah et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Abir Ziyad Qamhiyah (Ames, Iowa); Donald Flugrad (Ames, Iowa) |
ABSTRACT | One implementation provides a method to provide information associated with a previously designed component having a geometry that is similar to a geometry of a source component. In this implementation, the method includes obtaining a first set of coefficients for a non-invertible representation of the geometry of the source component, and comparing the first set of coefficients to a second set of coefficients for a non-invertible representation of the geometry of the previously designed component. If the first set of coefficients matches the second set of coefficients according to a threshold of similarity, the method further includes providing a search result associated with the previously designed component. |
FILED | Thursday, April 19, 2007 |
APPL NO | 11/737520 |
ART UNIT | 2166 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/706 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779230 | Balakrishnan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Saisanthosh Balakrishnan (Madison, Wisconsin); Gurindar Singh Sohi (Madison, Wisconsin) |
ABSTRACT | Distant parallelization of sequential programs is obtained by making parallelization decisions at the boundaries between program methods (e.g., functions and sub-routines). Experimentation suggests that such a partitioning allows for large-scale parallelization without data flow conflicts. |
FILED | Wednesday, October 18, 2006 |
APPL NO | 11/550687 |
ART UNIT | 2181 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/31 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779326 | Stankovic et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
INVENTOR(S) | Vladimir M. Stankovic (Bryan, Texas); Angelos D. Liveris (Stafford, Texas); Zixiang Xiong (Spring, Texas); Costas N. Georghiades (College Station, Texas) |
ABSTRACT | System and method for designing Slepian-Wolf codes by channel code partitioning. A generator matrix is partitioned to generate a plurality of sub-matrices corresponding respectively to a plurality of correlated data sources. The partitioning is performed in accordance with a rate allocation among the plurality of correlated data sources. A corresponding plurality of parity matrices are generated based respectively on the sub-matrices, where each parity matrix is useable to encode data from a respective one of the correlated data sources. |
FILED | Tuesday, March 01, 2005 |
APPL NO | 11/069935 |
ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/752 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07775086 | Jesse et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Stephen Jesse (Knoxville, Tennessee); Sergei V. Kalinin (Knoxville, Tennessee) |
ABSTRACT | Methods and apparatus are described for scanning probe microscopy. A method includes generating a band excitation (BE) signal having finite and predefined amplitude and phase spectrum in at least a first predefined frequency band; exciting a probe using the band excitation signal; obtaining data by measuring a response of the probe in at least a second predefined frequency band; and extracting at least one relevant dynamic parameter of the response of the probe in a predefined range including analyzing the obtained data. The BE signal can be synthesized prior to imaging (static band excitation), or adjusted at each pixel or spectroscopy step to accommodate changes in sample properties (adaptive band excitation). An apparatus includes a band excitation signal generator; a probe coupled to the band excitation signal generator; a detector coupled to the probe; and a relevant dynamic parameter extractor component coupled to the detector, the relevant dynamic parameter extractor including a processor that performs a mathematical transform selected from the group consisting of an integral transform and a discrete transform. |
FILED | Friday, September 01, 2006 |
APPL NO | 11/515348 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/105 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775305 | Fischer |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Gary J. Fischer (Albuquerque, New Mexico) |
ABSTRACT | The present invention provides robotic vehicles having wheeled and hopping mobilities that are capable of traversing (e.g. by hopping over) obstacles that are large in size relative to the robot and, are capable of operation in unpredictable terrain over long range. The present invention further provides combustion powered linear actuators, which can include latching mechanisms to facilitate pressurized fueling of the actuators, as can be used to provide wheeled vehicles with a hopping mobility. |
FILED | Thursday, August 31, 2006 |
APPL NO | 11/513717 |
ART UNIT | 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Motor vehicles 180/8.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775368 | Schwartz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David Charles Schwartz (Madison, Wisconsin); Eileen T. Dimalanta (Madison, Wisconsin); Juan J. de Pablo (Madison, Wisconsin) |
ABSTRACT | Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten, align, separate, and/or sort the polymeric molecules. The polymeric molecules may be analyzed and/or manipulated in the carrier liquid or attached to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge. |
FILED | Friday, October 17, 2003 |
APPL NO | 10/688416 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Classifying, separating, and assorting solids 29/1 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775961 | Meikrantz |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | David H. Meikrantz (Idaho Falls, Idaho) |
ABSTRACT | Centrifuge samples may be exposed to microwave energy to heat the samples during centrifugation and to promote separation of the different components or constituents of the samples using a centrifuge device configured for generating microwave energy and directing the microwave energy at a sample located in the centrifuge. |
FILED | Monday, February 06, 2006 |
APPL NO | 11/349484 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Imperforate bowl: Centrifugal separators 494/37 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776357 | Davalos et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Livermore, California) |
INVENTOR(S) | Rafael V. Davalos (Oakland, California); Christopher R. B. Ellis (Oakland, California) |
ABSTRACT | Disclosed is an apparatus and method for inserting one or several chemical or biological species into phospholipid containers that are controlled within a microfluidic network, wherein individual containers are tracked and manipulated by electric fields and wherein the contained species may be chemically processed. |
FILED | Tuesday, February 05, 2008 |
APPL NO | 12/012839 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/450 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776405 | Bailey et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
INVENTOR(S) | Charles L. Bailey (Cross Junction, Virginia); Victor Morozov (Manassas, Virginia); Nikolai N. Vsevolodov (Kensington, Maryland) |
ABSTRACT | The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters. |
FILED | Friday, November 17, 2006 |
APPL NO | 11/561138 |
ART UNIT | 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Coating processes 427/483 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776479 | Sopchak et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | David A. Sopchak (Livermore, California); Jeffrey D. Morse (Martinez, California); Ravindra S. Upadhye (Pleasanton, California); Jack Kotovsky (Oakland, California); Robert T. Graff (Modesto, California) |
ABSTRACT | A phosphoric acid fuel cell system comprising a porous electrolyte support, a phosphoric acid electrolyte in the porous electrolyte support, a cathode electrode contacting the phosphoric acid electrolyte, and an anode electrode contacting the phosphoric acid electrolyte. |
FILED | Thursday, April 28, 2005 |
APPL NO | 11/119525 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776532 | Gibson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Synthetic Genomics, Inc. (San Diego, California) |
INVENTOR(S) | Daniel Glenn Gibson (Crofton, Maryland); Hamilton O. Smith (Reisterstown, Maryland) |
ABSTRACT | The present invention relates, e.g., to an in vitro method, using isolated protein reagents, for joining two double-stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity, comprising (a) chewing back the DNA molecules with an enzyme having an exonuclease activity, to yield single-stranded overhanging portions of each DNA molecule which contain a sufficient length of the region of sequence identity to hybridize specifically to each other; (b) specifically annealing the single-stranded overhangs; and (c) repairing single-stranded gaps in the annealed DNA molecules and sealing the nicks thus formed (ligating the nicked DNA molecules). The region of sequence identity generally comprises at least 20 non-palindromic nucleotides (nt), e.g., at least about 40 non-palindromic nt. In some embodiments of the invention, about 5% PEG is present during all steps of the reaction, and/or the repair reaction is achieved with Taq DNA polymerase and a compatible ligase, such as Taq DNA ligase. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. It can be used, e.g., to join synthetically produced sub-fragments of a gene or genome of interest. |
FILED | Friday, August 11, 2006 |
APPL NO | 11/502624 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776642 | Eriksson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Mark A. Eriksson (Madison, Wisconsin); Max G. Lagally (Madison, Wisconsin); Arnold Melvin Kiefer (Madison, Wisconsin) |
ABSTRACT | A quantum-well photoelectric device, such as a quantum cascade laser, is constructed of monocrystalline nanoscale membranes physically removed from a substrate and mechanically assembled into a stack. |
FILED | Thursday, May 15, 2008 |
APPL NO | 12/120933 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/74 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776780 | Granite et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Evan J. Granite (Wexford, Pennsylvania); Henry W. Pennline (Bethel Park, Pennsylvania) |
ABSTRACT | Two new classes of catalysts for the removal of heavy metal contaminants, especially mercury (Hg) from effluent gases. Both of these classes of catalysts are excellent absorbers of HCl and Cl2 present in effluent gases. This adsorption of oxidizing agents aids in the oxidation of heavy metal contaminants. The catalysts remove mercury by oxidizing the Hg into mercury (II) moieties. For one class of catalysts, the active component is selected from the group consisting of iridium (Ir) and iridum-platinum (Ir/Pt) alloys. The Ir and Ir/Pt alloy catalysts are especially corrosion resistant. For the other class of catalyst, the active component is partially combusted coal or “Thief” carbon impregnated with Cl2. Untreated Thief carbon catalyst can be self-activating in the presence of effluent gas streams. The Thief carbon catalyst is disposable by means of capture from the effluent gas stream in a particulate collection device (PCD). |
FILED | Thursday, July 14, 2005 |
APPL NO | 11/183221 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/181 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776782 | Werpy et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Todd Werpy (West Richland, Washington); John G. Frye, Jr. (Richland, Washington); Yong Wang (Richland, Washington); Alan H. Zacher (Kennewick, Washington) |
ABSTRACT | A textured catalyst having a hydrothermally-stable support, a metal oxide and a catalyst component is described. Methods of conducting aqueous phase reactions that are catalyzed by a textured catalyst are also described. The invention also provides methods of making textured catalysts and methods of making chemical products using a textured catalyst. |
FILED | Monday, January 08, 2007 |
APPL NO | 11/651360 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/185 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776999 | Mayer-Cumblidge et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | M. Uljana Mayer-Cumblidge (Richland, Washington); Haishi Cao (Richland, Washington) |
ABSTRACT | A molecular probe comprises two arsenic atoms and at least one cyanine based moiety. A method of producing a molecular probe includes providing a molecule having a first formula, treating the molecule with HgOAc, and subsequently transmetallizing with AsCl3. The As is liganded to ethanedithiol to produce a probe having a second formula. A method of labeling a peptide includes providing a peptide comprising a tag sequence and contacting the peptide with a biarsenical molecular probe. A complex is formed comprising the tag sequence and the molecular probe. A method of studying a peptide includes providing a mixture containing a peptide comprising a peptide tag sequence, adding a biarsenical probe to the mixture, and monitoring the fluorescence of the mixture. |
FILED | Thursday, April 12, 2007 |
APPL NO | 11/787078 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777016 | Okumoto et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia) |
INVENTOR(S) | Sakiko Okumoto (Washington, District of Columbia); Loren L. Looger (Washington, District of Columbia); Wolf B. Frommer (Washington, District of Columbia) |
ABSTRACT | Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture. |
FILED | Friday, October 14, 2005 |
APPL NO | 11/665343 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777182 | Dahl et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | David A. Dahl (Idaho Falls, Idaho); Jill R. Scott (Idaho Falls, Idaho); Timothy R. McJunkin (Idaho Falls, Idaho) |
ABSTRACT | An ion cyclotron spectrometer may include a vacuum chamber that extends at least along a z-axis and means for producing a magnetic field within the vacuum chamber so that a magnetic field vector is generally parallel to the z-axis. The ion cyclotron spectrometer may also include means for producing a trapping electric field within the vacuum chamber that includes at least a first section that induces a first magnetron effect that increases a cyclotron frequency of an ion and at least a second section that induces a second magnetron effect that decreases the cyclotron frequency of an ion. The cyclotron frequency changes induced by the first and second magnetron effects substantially cancel one another so that an ion traversing the at least first and second sections will experience no net change in cyclotron frequency. |
FILED | Thursday, August 02, 2007 |
APPL NO | 11/833079 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777185 | de Jonge |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Niels de Jonge (Oak Ridge, Tennessee) |
ABSTRACT | A confocal scanning transmission electron microscope which includes an electron illumination device providing an incident electron beam propagating in a direction defining a propagation axis, and a precision specimen scanning stage positioned along the propagation axis and movable in at least one direction transverse to the propagation axis. The precision specimen scanning stage is configured for positioning a specimen relative to the incident electron beam. A projector lens receives a transmitted electron beam transmitted through at least part of the specimen and focuses this transmitted beam onto an image plane, where the transmitted beam results from the specimen being illuminated by the incident electron beam. A detection system is placed approximately in the image plane. |
FILED | Tuesday, September 25, 2007 |
APPL NO | 11/860760 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/311 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777233 | Kahen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Eastman Kodak Company (Rochester, New York) |
INVENTOR(S) | Keith B. Kahen (Rochester, New York); Xiaofan Ren (Rochester, New York) |
ABSTRACT | An optoelectronic device including two spaced apart electrodes; and at least one layer containing ternary core/shell nanocrystals disposed between the spaced electrodes and having ternary semiconductor cores containing a gradient in alloy composition and wherein the ternary core/shell nanocrystals exhibit single molecule non-blinking behavior characterized by on times greater than one minute or radiative lifetimes less than 10 ns. |
FILED | Tuesday, October 30, 2007 |
APPL NO | 11/928292 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/79 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777303 | Alivisatos et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | A. Paul Alivisatos (Oakland, California); Janke J. Dittmer (Munich, Germany); Wendy U. Huynh (Munich, Germany); Delia Milliron (Berkeley, California) |
ABSTRACT | The invention described herein provides for thin films and methods of making comprising inorganic semiconductor-nanocrystals dispersed in semiconducting-polymers in high loading amounts. The invention also describes photovoltaic devices incorporating the thin films. |
FILED | Tuesday, March 18, 2003 |
APPL NO | 10/392668 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Active solid-state devices 257/615 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777516 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Eaton Corporation (Cleveland, Ohio) |
INVENTOR(S) | Wei Zhou (Los Angeles, California); Bin Lu (Kenosha, Wisconsin); Thomas G. Habetler (Snellville, Georgia); Ronald G. Harley (Lawrenceville, Georgia); Peter J. Theisen (West Bend, Wisconsin) |
ABSTRACT | A system and method for detecting incipient mechanical motor faults by way of current noise cancellation is disclosed. The system includes a controller configured to detect indicia of incipient mechanical motor faults. The controller further includes a processor programmed to receive a baseline set of current data from an operating motor and define a noise component in the baseline set of current data. The processor is also programmed to repeatedly receive real-time operating current data from the operating motor and remove the noise component from the operating current data in real-time to isolate any fault components present in the operating current data. The processor is then programmed to generate a fault index for the operating current data based on any isolated fault components. |
FILED | Tuesday, June 03, 2008 |
APPL NO | 12/132056 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Electricity: Measuring and testing 324/772 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777665 | Doerry et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Armin W. Doerry (Albuquerque, New Mexico); Freddie E. Heard (Albuquerque, New Mexico); J. Thomas Cordaro (Albuquerque, New Mexico) |
ABSTRACT | Motion measurement errors that extend beyond the range resolution of a synthetic aperture radar (SAR) can be corrected by effectively decreasing the range resolution of the SAR in order to permit measurement of the error. Range profiles can be compared across the slow-time dimension of the input data in order to estimate the error. Once the error has been determined, appropriate frequency and phase correction can be applied to the uncompressed input data, after which range and azimuth compression can be performed to produce a desired SAR image. |
FILED | Wednesday, May 14, 2008 |
APPL NO | 12/120270 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.E00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779173 | Archer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Jeffrey J. Parker (Rochester, Minnesota) |
ABSTRACT | Methods, apparatus, and products are disclosed for DMA transfer completion notification that include: inserting, by an origin DMA engine on an origin compute node in an injection FIFO buffer, a data descriptor for an application message to be transferred to a target compute node on behalf of an application on the origin compute node; inserting, by the origin DMA engine, a completion notification descriptor in the injection FIFO buffer after the data descriptor for the message, the completion notification descriptor specifying an address of a completion notification field in application storage for the application; transferring, by the origin DMA engine to the target compute node, the message in dependence upon the data descriptor; and notifying, by the origin DMA engine, the application that the transfer of the message is complete, including performing a local direct put operation to store predesignated notification data at the address of the completion notification field. |
FILED | Tuesday, May 29, 2007 |
APPL NO | 11/754719 |
ART UNIT | 2181 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital data processing systems: Input/output 710/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE41504 | Maziasz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
INVENTOR(S) | Philip J. Maziasz (Oak Ridge, Tennessee); Tim McGreevy (Washington, Illinois); Michael James Pollard (Peoria, Illinois); Chad W. Siebenaler (Dunlap, Illinois); Robert W. Swindeman (Oak Ridge, Tennessee) |
ABSTRACT | A CF8C type stainless steel alloy and articles formed therefrom containing about 18.0 weight percent to about 22.0 weight percent chromium and 11.0 weight percent to about 14.0 weight percent nickel; from about 0.05 weight percent to about 0.15 weight percent carbon; from about 2.0 weight percent to about 10.0 weight percent manganese; and from about 0.3 weight percent to about 1.5 weight percent niobium. The present alloys further include less than 0.15 weight percent sulfur which provides high temperature strength both in the matrix and at the grain boundaries without reducing ductility due to cracking along boundaries with continuous or nearly-continuous carbides. The disclosed alloys also have increased nitrogen solubility thereby enhancing strength at all temperatures because nitride precipitates or nitrogen porosity during casting are not observed. The solubility of nitrogen is dramatically enhanced by the presence of manganese, which also retains or improves the solubility of carbon thereby providing additional solid solution strengthening due to the presence of manganese and nitrogen, and combined carbon. |
FILED | Monday, August 25, 2008 |
APPL NO | 12/230179 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Metal treatment 148/327 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07776337 | Stern et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Norman J Stern (Athens, Georgia); Edward A Svetoch (Serpukhov District, Russian Federation); Boris V Eruslanov (Serpukhov District, Russian Federation); Vladimir V Perelygin (Serpukhov District, Russian Federation); Vladimir P Levchuk (Serpukhov District, Russian Federation); Larisa I Volodina (Serpukhov District, Russian Federation); Yuri N. Kovalev (Serpukhov District, Russian Federation); Tamara Y. Kudryavtseva (Serpukhov District, Russian Federation); Victor D. Pokhilenko (Serpukhov District, Russian Federation); Valery N. Borzenkov (Serpukhov District, Russian Federation); Olga E. Svetoch (Serpukhov District, Russian Federation); Eugeni V. Mitsevich (Serpukhov Distict, Russian Federation); Irina P. Mitsevich (Serpukhov District, Russian Federation) |
ABSTRACT | Novel bacteriocins and/or the novel lactic acid-producing strains are used for at least reducing the levels of colonization by at least one target bacteria in animals, especially poultry. |
FILED | Friday, August 15, 2008 |
APPL NO | 12/192778 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP21217 | Henny et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
INVENTOR(S) | Richard Henny (Tavares, Florida); Jianjun Chen (Apopka, Florida) |
ABSTRACT | A new Epipremnum plant particularly distinguished by having small variegated leaves with three different colors, irregularly undulated rather than smooth leaf surfaces, and compact and dense growth habit, is disclosed. |
FILED | Tuesday, December 09, 2008 |
APPL NO | 12/316132 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07774951 | Hartmann et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
ABSTRACT | A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip. |
FILED | Wednesday, October 03, 2007 |
APPL NO | 11/906751 |
ART UNIT | 2841 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Geometrical instruments 033/552 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07775261 | Valenzuela |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Mikros Manufacturing, Inc. (Claremont, New Hampshire) |
INVENTOR(S) | Javier A. Valenzuela (Grantham, New Hampshire) |
ABSTRACT | A heat transfer device is disclosed for transferring heat to or from a fluid that is undergoing a phase change. The heat transfer device includes a liquid-vapor manifold in fluid communication with a capillary structure thermally connected to a heat transfer interface, all of which are disposed in a housing to contain the vapor. The liquid-vapor manifold transports liquid in a first direction and conducts vapor in a second, opposite direction. The manifold provides a distributed supply of fluid (vapor or liquid) over the surface of the capillary structure. In one embodiment, the manifold has a fractal structure including one or more layers, each layer having one or more conduits for transporting liquid and one or more openings for conducting vapor. Adjacent layers have an increasing number of openings with decreasing area, and an increasing number of conduits with decreasing cross-sectional area, moving in a direction toward the capillary structure. |
FILED | Tuesday, March 08, 2005 |
APPL NO | 11/075467 |
ART UNIT | 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Heat exchange 165/104.260 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 07778183 | Fan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Jinliang Fan (Redmond, Washington); Nagui Halim (Yorktown Heights, New York); Zhen Liu (Tarrytown, New York); Dimitrios Pendarakis (Westport, Connecticut) |
ABSTRACT | A method is provided for selecting a replication node from eligible nodes in a network. A multidimensional model is constructed that defines a multidimensional space and includes the eligible nodes, with each of the dimensions of the multidimensional model being a system characteristic. A data availability value is determined for each of the eligible nodes, and a cost of deploying is determined for each of at least two availability strategies to the eligible nodes. At least one of the eligible nodes is selected for replication of data that is stored on a source node in the network. The selecting step includes selecting the eligible node whose: data availability value is determined to be highest among the eligible nodes whose cost of deploying does not exceed a specified maximum, or cost of deploying is determined to be lowest among the eligible nodes whose data availability value does not exceed a specified minimum. |
FILED | Tuesday, February 20, 2007 |
APPL NO | 11/676631 |
ART UNIT | 2471 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/238 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779298 | Challenger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | James R. Challenger (Garrison, New York); Louis R. Degenaro (White Plains, New York); James R. Giles (Yorktown Heights, New York); Gabriela Jacques Da Silva (Champaign, Illinois) |
ABSTRACT | A method is provided for the recovery of an instance of a job manager running on one of a plurality of nodes used to execute the processing elements associated with jobs that are executed within a cooperative data stream processing system. The states of the processing elements are checkpointed to a persistence mechanism in communication with the job manager. From the checkpointed processing element states, the state of each distributed job is determined and checkpointed. Processing element states are also checkpointed locally to the nodes one which the processing elements are running. Following a failure of the job manager, the job manager is reinstantiated on one of the nodes. The recovery instance of the job manger obtains state data for processing elements and jobs from the persistence mechanism and constructs an initial state for jobs and processing elements. These initial states are reconciled against the current states of the processing elements and adjustments are made accordingly. Once the job and processing element states are reconciled, the system is returned to normal operation. |
FILED | Monday, June 11, 2007 |
APPL NO | 11/761152 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 07776553 | Love et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Presidents and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | J. Christopher Love (Cambridge, Massachusetts); Hidde L. Ploegh (Brookline, Massachusetts); Jehnna Ronan (Chester, New Hampshire) |
ABSTRACT | Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with each other. In some examples, the assays and methods may be used to determine if a known antigen binds to an unknown monoclonal antibody. |
FILED | Monday, September 18, 2006 |
APPL NO | 11/523124 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07777016 | Okumoto et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia) |
INVENTOR(S) | Sakiko Okumoto (Washington, District of Columbia); Loren L. Looger (Washington, District of Columbia); Wolf B. Frommer (Washington, District of Columbia) |
ABSTRACT | Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture. |
FILED | Friday, October 14, 2005 |
APPL NO | 11/665343 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 07775174 | Humphreys et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Vehicle Control Technologies, Inc. (Reston, Virginia) |
INVENTOR(S) | Douglas E. Humphreys (Great Falls, Virginia); Ryan D. Schulz (Reston, Virginia); Alexander V. Roup (Sterling, Virginia); Neill S. Smith (Springfield, Virginia); Daniel N. Dietz (Alexandria, Virginia) |
ABSTRACT | An at least partially self-propelled vehicle is configured for being towed by a towing vehicle, by way of a tow line. Operation of the vehicles may be coordinated so that, for a length of the tow line that connects the vehicles, the length of the tow line is curved in a manner that inhibits the tow line from transferring oscillatory motion between the vehicles while the entirety of the length of the tow line may be under tension. |
FILED | Friday, August 29, 2008 |
APPL NO | 12/231238 |
ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ships 114/244 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776153 | Schowalter et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
INVENTOR(S) | Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (East Setauket, New York) |
ABSTRACT | A method and apparatus for producing bulk single crystals of AlN having low dislocation densities of about 10,000 cm−2 or less includes a crystal growth enclosure with Al and N2 source material therein, capable of forming bulk crystals. The apparatus maintains the N2 partial pressure at greater than stoichiometric pressure relative to the Al within the crystal growth enclosure, while maintaining the total vapor pressure in the crystal growth enclosure at super-atmospheric pressure. At least one nucleation site is provided in the crystal growth enclosure, and provision is made for cooling the nucleation site relative to other locations in the crystal growth enclosure. The Al and N2 vapor is then deposited to grow single crystalline low dislocation density AlN at the nucleation site. High efficiency ultraviolet light emitting diodes and ultraviolet laser diodes are fabricated on low defect density AlN substrates, which are cut from the low dislocation density AlN crystals. Bulk crystals of ZnO may also be produced using the method. |
FILED | Thursday, November 03, 2005 |
APPL NO | 11/265909 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/81 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 07778840 | Krause et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Robert Krause (Severna Park, Maryland); Wayne H. Orbke (Germantown, Tennessee); Harry W. Aldstadt (Woodbridge, Virginia); Michael Murphy (Collierville, Tennessee); Audrey K. Conley Williams (Memphis, Tennessee); Gerald Matthews (Germantown, Tennessee); Pat Matthews, legal representative (Germnatown, Tennessee); Michael Selnick (Reston, Virginia) |
ABSTRACT | This disclosure describes systems and methods for collecting and processing change of address data and providing change of address services to a customer using a computer network. The address data can include a physical address, an electronic address, or both. The systems and methods may also provide additional services to the customer to assist in changing addresses. |
FILED | Monday, April 23, 2001 |
APPL NO | 09/839241 |
ART UNIT | 3714 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/1 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07779481 | Chamberlain |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Charles R. Chamberlain (Arlington, Virginia) |
ABSTRACT | Systems and mehods for electronic postmarking of location data are provided. Electronic postmarking of location data (S.20) includes generating a hash value corresponding to merged data (S.30). Electronic postmarking further includes generating an electronic postmark data structure (S.40) comprising the hash value and a date/time stamp. The electronic postmarking data structure (S.40) may further include a digital signature. |
FILED | Friday, April 12, 2002 |
APPL NO | 10/474730 |
ART UNIT | 2432 — Cryptography and Security |
CURRENT CPC | Information security 726/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07776240 | Chu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
INVENTOR(S) | Chih-Chang Chu (Ithaca, New York); Xian-Zheng Zhang (Wuhan, China PRC); Da-Qing Wu (Ithaca, New York) |
ABSTRACT | Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution. |
FILED | Thursday, December 04, 2003 |
APPL NO | 10/538477 |
ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/4.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 07775261 | Valenzuela |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Mikros Manufacturing, Inc. (Claremont, New Hampshire) |
INVENTOR(S) | Javier A. Valenzuela (Grantham, New Hampshire) |
ABSTRACT | A heat transfer device is disclosed for transferring heat to or from a fluid that is undergoing a phase change. The heat transfer device includes a liquid-vapor manifold in fluid communication with a capillary structure thermally connected to a heat transfer interface, all of which are disposed in a housing to contain the vapor. The liquid-vapor manifold transports liquid in a first direction and conducts vapor in a second, opposite direction. The manifold provides a distributed supply of fluid (vapor or liquid) over the surface of the capillary structure. In one embodiment, the manifold has a fractal structure including one or more layers, each layer having one or more conduits for transporting liquid and one or more openings for conducting vapor. Adjacent layers have an increasing number of openings with decreasing area, and an increasing number of conduits with decreasing cross-sectional area, moving in a direction toward the capillary structure. |
FILED | Tuesday, March 08, 2005 |
APPL NO | 11/075467 |
ART UNIT | 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Heat exchange 165/104.260 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07776326 | Milbrandt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
INVENTOR(S) | Jeffrey Milbrandt (St. Louis, Missouri); Toshiyuki Araki (Tokyo, Japan); Yo Sasaki (Saint Louis, Missouri) |
ABSTRACT | Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies. |
FILED | Friday, June 03, 2005 |
APPL NO | 11/144358 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07776327 | Kinch et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Michael S. Kinch (Laytonsville, Maryland); Nicole D. Zantek (Silver Spring, Maryland); Patrick W. Hein (Columbia, Illinois) |
ABSTRACT | The present invention is directed to compounds and methods for the treatment of cancer. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase that is overexpressed in metastatic tumor cells. The compounds used in accordance with this invention may be provided in a pharmaceutical composition for treatment of metastatic cancer. |
FILED | Thursday, December 08, 2005 |
APPL NO | 11/297548 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 17, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100817.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page