FedInvent™ Patents

Patent Details for Tuesday, August 17, 2010 

This page was updated on Monday, March 27, 2023 at 01:53 AM GMT

Department of Health and Human Services (HHS) 

US 07775368 Schwartz et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) David Charles Schwartz (Madison, Wisconsin);  Eileen T. Dimalanta (Madison, Wisconsin);  Juan J. de Pablo (Madison, Wisconsin)
ABSTRACT Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten, align, separate, and/or sort the polymeric molecules. The polymeric molecules may be analyzed and/or manipulated in the carrier liquid or attached to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge.
FILED Friday, October 17, 2003
APPL NO 10/688416
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Classifying, separating, and assorting solids
29/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775469 Poznansky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Mark C. Poznansky (Charlestown, Massachusetts);  Andrew D. Luster (Wellesley, Massachusetts);  David T. Scadden (Weston, Massachusetts)
ABSTRACT This invention relates to methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention relates to methods and compositions for modulating movement of cells of hematopoietic, neural, epithelial, or mesenchymal origin, in a specific site in a subject. The foregoing are useful, inter alia, in the treatment of conditions characterized by a need to modulate migratory-cell movement associated with specific sites in a subject. More specifically, specific sites include sites of inflammation and modulation of migratory-cell movement is movement away from an agent source, or repulsion. Other sites include tumor sites, sites of pathogenic infection, and germ cell bearing sites.
FILED Thursday, April 20, 2006
APPL NO 11/407477
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Winding, tensioning, or guiding
242/85.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775979 Thomenius et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Kai E. Thomenius (Clifton Park, New York);  Robert Gideon Wodnicki (Niskayuna, New York);  Ye-Ming Li (Schenectady, New York)
ABSTRACT An ultrasonic transducer probe having a highly integrated interface circuit array. Low-voltage transmit control signals from the system are transmitted on the system transmit channels via the ultrasound probe cable and into the interface circuit array. These transmit control signals are routed through the interface circuit array using a dense switching matrix. Once the low-voltage transmit control signals reach individual cells within the interface array, they are decoded and used to control local high-voltage pulser circuits to drive individual ultrasound transducer elements made up of selected subelements that are co-integrated with the interface electronics. The interface cell circuitry further comprises a high-voltage transmit/receive switch, which is closed when the high-voltage pulser is transmitting to protect the low-voltage components.
FILED Wednesday, June 29, 2005
APPL NO 11/172599
ART UNIT 3768 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Surgery
6/437
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US 07776197 Zhou
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Dao Min Zhou (Saugus, California)
ABSTRACT An electrode surface coating and method for manufacturing the electrode surface coating comprising a conductive substrate; and one or more surface coatings comprising one or more of the following metals titanium, niobium, tantalum, ruthenium, rhodium, iridium, palladium, or gold, or an alloy of two or more metals, or a combination of two or more alloys or metal layers thereof having an increase in the surface area of 5 times to 500 times of the corresponding surface area resulting from the basic geometric shape.
FILED Tuesday, December 30, 2008
APPL NO 12/346571
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/99
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US 07776292 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) CDIC, Inc. (Atlanta, Georgia);  The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  CDG Research Corporation (Bethlehem, Pennsylvania)
INVENTOR(S) Deborah E. Wilson (Dunn Loring, Virginia);  Katherine K. Lock (Bethesda, Maryland);  Murray L. Cohen (Fort Worth, Texas);  Thomas E. McWhorter (Allentown, Pennsylvania);  Aaron A. Rosenblatt (New York, New York);  Theodore J. Traum (Rio Rancho, New Mexico)
ABSTRACT The present disclosure relates to the decontamination of articles contaminated (or thought to be contaminated) with bioweapons, such as methods and apparatus for decontaminating articles contaminated with sporualated bioweapons. In some embodiments, the methods are methods of decontaminating an environment, for example a room or building contaminated with a bioweapon.
FILED Thursday, January 13, 2005
APPL NO 10/597191
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/295
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US 07776313 Fish et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University Health Network (Ontario, Canada);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Eleanor Fish (Toronto, Canada);  Carole Galligan (Scarborough, Canada);  Kathy Siminovitch (Toronto, Canada);  Omar Perez (San Francisco, California);  Edward Keystone (Toronto, Canada);  Vivian Bykerk (Toronto, Canada)
ABSTRACT The invention provides a novel cell that is a precursor of a fibroblast-like synovial cell. The novel cell is a circulating synovial tissue cell that stains positive for collagen, CD34, CD45, prolyl 4-hydroxylase and CD14. The invention also relates to methods of diagnosing or monitoring rheumatoid arthritis and/or osteoarthritis using gene expression profiles, protein expression profiles, and/or protein phosphorylation profiles of different cell types, including the novel precursor, CD3+ cells, synovial tissue fibroblast-like synovial cells and fibrocytes. The invention also includes methods to identify substances to treat or prevent rheumatoid arthritis and/or osteoarthritis.
FILED Friday, May 25, 2007
APPL NO 11/807088
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.100
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US 07776330 Yazaki et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Paul J. Yazaki (Glendale, California);  Mark A. Sherman (Pasadena, California);  John E. Shively (Arcadia, California);  Andrew A. Raubitschek (San Marino, California);  Anna M. Wu (Sherman Oaks, California)
ABSTRACT Embodiments of the present invention utilize a more efficient CDR grafting technique to generate humanized versions of the T84.66 antibody. The technique used to generate these antibodies utilizes crystallographic structural data to select an immunoglobulin framework having maximum structural overlap with a non-human donor molecule. This technique was used to develop humanized T84.66 antibodies exhibiting in vitro binding affinity and specificity for carcinoembryonic antigen (CEA) nearly identical to that of T84.66 and the ability to specifically target tumors expressing CEA in vivo.
FILED Tuesday, September 25, 2007
APPL NO 11/861093
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/133.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776334 Scadden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) David T. Scadden (Weston, Massachusetts);  Laura M. Calvi (Rochester, New York);  Gregor Adams (Boston, Massachusetts);  Henry M. Kronenberg (Belmont, Massachusetts)
ABSTRACT The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.
FILED Thursday, August 28, 2008
APPL NO 12/200419
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776336 Grandi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Novartis Vaccines and Diagnostics SRL (Siena, Italy)
INVENTOR(S) Guido Grandi (Segrate, Italy);  John Telford (Monteriggioni, Italy);  Renata Maria Grifantini (Siena, Italy)
ABSTRACT Disclosed are several Y. pestis antigens that are particularly suitable for immunisation purposes, particularly when used in combinations.
FILED Wednesday, October 25, 2006
APPL NO 12/091604
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/190.100
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US 07776338 Connell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Terry D. Connell (Williamsville, New York);  Michael W. Russell (East Amherst, New York);  Hesham Nawar (Buffalo, New York);  Sergio Arce (Williamsville, New York)
ABSTRACT The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens.
FILED Wednesday, November 05, 2008
APPL NO 12/265516
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/190.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776341 Belisle et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado);  New York University (New York, New York)
INVENTOR(S) John T. Belisle (Fort Collins, Colorado);  Mark J. Sartain (Fort Collins, Colorado);  Suman Laal (Cortlandt Manor, New York)
ABSTRACT Mycobacterial proteins from culture filtrate or cytosol are disclosed as being useful B cell antigens for early diagnosis of mycobacterial disease, particularly in humans. These proteins include four that had not previously been recognized as B cell antigens (LppZ protein encoded by Mtb gene Rv3006; SodC protein encoded by Mtb gene Rv0432; BfrB protein encoded by Mtb gene Rv3841 and TrxC protein encoded by Mtb gene Rv3914). Antigenic compositions include these proteins and/or peptide fragments thereof, in various combinations with each other or with one or more of a set of 10 additional Mtb proteins known to be antigens (in particular early antigens. Methods and kits for using these antigenic composition for early diagnosis of mycobacterial infection and disease are also disclosed.
FILED Friday, August 10, 2007
APPL NO 11/837264
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/248.100
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US 07776344 Hartmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa);  Coley Pharmaceutical GmbH (Dusseldorf, Germany);  Coley Pharmaceutical Group, Inc. (New York, New York)
INVENTOR(S) Gunther Hartmann (Munich, Germany);  Robert L. Bratzler (Concord, Massachusetts);  Arthur M. Krieg (Wellesley, Massachusetts)
ABSTRACT Methods and compositions are provided for extending the clinical utility of IFN-α in the treatment of a variety of viral and proliferative disorders. Among other aspects, the invention provides methods which increase the efficacy of IFN-α treatment and reduce IFN-α treatment-related side effects. In addition, methods are provided for supporting the survival and for activating natural interferon producing cells (IPCs) in vitro without exogenous IL-3 or GM-CSF. The invention is based on the discovery that certain CpG and non-CpG ISNAs promote survival and stimulation of IPCs.
FILED Friday, July 08, 2005
APPL NO 11/179008
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/278.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776361 Ting
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kang Ting (Beverly Hills, California)
ABSTRACT This invention pertains to the discovery that the human NELL-1 gene induces or upregulates bone mineralization. The NELL-1 gene or gene product thus provides a convenient target for screening for modulators of bone mineralization. In addition, NELL-1 can be used to facilitate repair of bone fractures and/or to generally increase bone density.
FILED Tuesday, March 28, 2006
APPL NO 11/392294
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/549
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US 07776518 Altieri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Dario C. Altieri (Worcester, Massachusetts);  Robert M. Weiss (North Haven, Connecticut);  Shannon D. Smith (Guilford, Connecticut);  Victor A. Morris, legal representative (Guilford, Connecticut);  Marcia A. Wheeler (Branford, Connecticut);  Janet Plescia (Meriden, Connecticut)
ABSTRACT The present invention includes a method for diagnosing cancer and predicting recurrent cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
FILED Wednesday, June 18, 2003
APPL NO 10/463867
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
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US 07776520 Fisher
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) David E. Fisher (Newton, Massachusetts)
ABSTRACT Microphthalmia (Mi) while present in melanocytes, a cells and osteoclast, is not normally present in other cells. We have found that Mi is present in the nucleus of melanoma cells. Melanoma can be diagnosed by contacting a malignant cell with a probe for Mi. If the probe identifies Mi in the nucleus of the cell, the cell is a melanoma.
FILED Wednesday, November 24, 2004
APPL NO 10/997018
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
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US 07776521 Rota et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
INVENTOR(S) Paul A. Rota (Decatur, Georgia);  Larry J. Anderson (Atlanta, Georgia);  William J. Bellini (Lilburn, Georgia);  Michael D. Bowen (Decatur, Georgia);  Cara Carthel Burns (Avondale Estates, Georgia);  Raymond Campagnoli (Decatur, Georgia);  Qi Chen (Marietta, Georgia);  James A. Comer (Decatur, Georgia);  Byron T. Cook (Augusta, Georgia);  Shannon L. Emery (Lusaka, Zambia);  Dean D. Erdman (Decatur, Georgia);  Cynthia S. Goldsmith (Lilburn, Georgia);  Jeanette Guarner (Decatur, Georgia);  Charles D. Humphrey (Lilburn, Georgia);  Joseph P. Icenogle (Atlanta, Georgia);  Thomas G. Ksiazek (Lilburn, Georgia);  Richard F. Meyer (Roswell, Georgia);  Stephan S. Monroe (Decatur, Georgia);  William Allan Nix (Bethlehem, Georgia);  M. Steven Oberste (Lilburn, Georgia);  Christopher D. Paddock (Atlanta, Georgia);  Teresa C. T. Peret (Atlanta, Georgia);  Pierre E. Rollin (Lilburn, Georgia);  Mark A. Pallansch (Lilburn, Georgia);  Anthony Sanchez (Lilburn, Georgia);  Wun-Ju Shieh (Norcross, Georgia);  Suxiang Tong (Alpharetta, Georgia);  Sherif R. Zaki (Atlanta, Georgia)
ABSTRACT Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.
FILED Monday, May 14, 2007
APPL NO 11/748359
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/5
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US 07776527 Hsu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Li-Chung Hsu (San Diego, California);  Michael Karin (La Jolla, California)
ABSTRACT The present invention relates to microbial infection, and in particular, the reduction of apoptosis associated with microbial infection, the screening of agents that reduce apoptosis, and the treatment and analysis of microbial infection in vivo. In one embodiment, the present invention relates to agents including but not limited to reducing the activity of Protein Kinase R.
FILED Friday, November 12, 2004
APPL NO 10/578976
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07776528 Lakowicz
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Joseph R. Lakowicz (Ellicot City, Maryland)
ABSTRACT Compositions and methods for increasing the fluorescence intensity of molecules are provided. In particular, compositions and methods directed to increasing the intrinsic fluorescence of biomolecules and low quantum yield fluorophores are described. The intrinsic fluorescence of biomolecules is increased by positioning a metal particle and a biomolecule at a distance apart sufficient to increase the radiative decay rate of the biomolecule. Methods for the identification of nucleic acids are also provided. The compositions and methods can also be used to increase the emission of any fluorophore, such as the extrinsic probes used to label biomolecules.
FILED Thursday, November 18, 2004
APPL NO 10/990549
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07776531 Black et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Illumina, Inc. (San Diego, California)
INVENTOR(S) Fiona E. Black (San Diego, California);  Steven M. Barnard (San Diego, California);  Nels A. Olson (San Diego, California)
ABSTRACT The present invention provides a method for detecting a target analyte by providing a substrate having attached polynucleotides and a stabilization polymer layer; removing the stabilization polymer layer; contacting the substrate with a target analyte; and detecting the target analyte.
FILED Friday, January 27, 2006
APPL NO 11/341115
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07776533 Agnew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Life Technologies Corporation (Carlsbad, California)
INVENTOR(S) Brian Agnew (Eugene, Oregon);  Joseph Beechem (Eugene, Oregon);  Kyle R Gee (Springfield, Oregon);  Richard P Haugland (Olympia, Washington);  Thomas H Steinberg (Eugene, Oregon);  Wayne F Patton (Newton, Massachusetts)
ABSTRACT The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target molecules that interact with phosphorylated target molecules or molecules capable of being phosphorylated. A binding solution is provide that comprises a phosphate-binding compound, an acid and a metal ion wherein the metal ion simultaneously interacts with an exposed phosphate group on a target molecule and the metal chelating moiety of the phosphate-binding compound forming a bridge between the phosphate-binding compound and a phosphorylated target molecule resulting in a ternary complex. The binding solution of the present invention finds use in binding and detecting immobilized and solubilized phosphorylated target molecules, isolation of phosphorylated target molecules from a complex mixture and aiding in proteomic analysis wherein kinase and phosphatase substrates and enzymes can be identified.
FILED Tuesday, October 24, 2006
APPL NO 11/552275
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07776536 Pinkel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Daniel Pinkel (Walnut Creek, California);  Donna Albertson (Cambridge, United Kingdom);  Joe W. Gray (San Francisco, California)
ABSTRACT The present invention provides methods of determining relative copy number of target nucleic acids and precise mapping of chromosomal abnormalities associated with disease. The methods of the invention use target nucleic acids immobilized on a solid surface, to which a sample comprising two sets of differentially labeled nucleic acids are hybridized. The hybridization of the labeled nucleic acids to the solid surface is then detected using standard techniques.
FILED Thursday, March 29, 2007
APPL NO 11/727935
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776541 Polyak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Dana-Faber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Kornelia Polyak (Brookline, Massachusetts);  Charlotta Enerback (Gothenburg, Sweden)
ABSTRACT The invention features methods of diagnosing high grade ductal carcinoma in situ (DCIS) These methods involve measuring: (1) the level of HID-5 in a body fluid (e.g., blood or urine) of a subject suspected of having, or at risk of having, high grade DCIS; or (2) the level of HID-5 gene expression in breast tissue from a subject suspected of having, or at risk of having, high grade DCIS. The invention also embodies a method of inhibiting expression of HID-5 protein in DCIS cells and methods of treating a subject suspected of having, or at risk of having, high grade DCIS.
FILED Monday, December 08, 2008
APPL NO 12/330342
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07776550 Block et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Philadelphia Health and Education Corporation (Philadelphia, Pennsylvania)
INVENTOR(S) Timothy M. Block (Doylestown, Pennsylvania);  Mary Ann Comunale (Bangor, Pennsylvania);  Anand Mehta (Lansdale, Pennsylvania)
ABSTRACT Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting glycosylation, and more specifically fucosylation, on proteins in biological fluids, and comparing the detected glycosylation with reference values for the glycosylation of such proteins in healthy or disease states.
FILED Friday, May 05, 2006
APPL NO 11/418598
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776553 Love et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Non-Profit Organization (NPO)
National Academy of Sciences
APPLICANT(S)
ASSIGNEE(S) Presidents and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) J. Christopher Love (Cambridge, Massachusetts);  Hidde L. Ploegh (Brookline, Massachusetts);  Jehnna Ronan (Chester, New Hampshire)
ABSTRACT Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with each other. In some examples, the assays and methods may be used to determine if a known antigen binds to an unknown monoclonal antibody.
FILED Monday, September 18, 2006
APPL NO 11/523124
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776563 Hazen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S) Stanley L. Hazen (Pepper Pike, Ohio);  Marc S. Penn (Beachwood, Ohio)
ABSTRACT The present invention provides methods and agents for treating subjects who have or are at risk of developing or having cardiovascular disease. Such agents inhibit binding of myeloperoxidase (MPO) to a molecule comprising the MPO binding site of apolipoprotein A-1 (apoA-1) and include a peptide fragment of apoA-1 comprising at least 4 contiguous amino acids in SEQ ID. NO: 2, a modified form of the apo-1 fragment comprising one or more D amino acids, a retro-inverso form of the apoA-1 peptide fragment, an organo-mimetic of the apoA-1 peptide fragment, a peptide-mimetic of the apoA1 peptide fragment, or a nucleic acid encoding the apo A-1 peptide fragment. The present invention also provides methods of identifying or screening test agents for treating subjects having or at risk of having or developing CVD. The method comprises incubating one or more test agents and MPO with a molecule comprising the MPO binding site of apoA-1 under conditions which permit binding of MPO to the MPO binding site and determining whether one or more of the agents inhibit such binding.
FILED Friday, May 23, 2008
APPL NO 12/126109
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/28
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776565 Betenbaugh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The John Hopkins University (Baltimore, Maryland);  Human Genome Sciences, Inc. (Rockville, Maryland)
INVENTOR(S) Michael J. Betenbaugh (Baltimore, Maryland);  Shawn Lawrence (Dobbs Ferry, New York);  Yuan C. Lee (Timonium, Maryland);  Timothy A. Coleman (Gaithersburg, Maryland)
ABSTRACT Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins.
FILED Friday, February 27, 2009
APPL NO 12/394479
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/84
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776591 Xia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma)
INVENTOR(S) Lijun Xia (Edmond, Oklahoma);  Rodger P. McEver (Oklahoma City, Oklahoma)
ABSTRACT A method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method, an effective amount of an α1,3-fucosyltransferase, e.g., α1,3-fucosyltransferase VI, is used in vitro to treat cord blood-derived hematopoietic stem cells to convert non-functional PSGL-1 or other ligands on the cell surface into functional forms that bind selectins, especially P-selectin or E-selectin. The treated cells have enhanced effectiveness in reconstituting bone marrow in patients in need of such therapy.
FILED Wednesday, June 07, 2006
APPL NO 11/448359
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/366
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776593 Levine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Fred Levine (Del Mar, California);  Bjoern Tyrberg (San Diego, California)
ABSTRACT The present invention provides methods of identifying endocrine stem and progenitor cells.
FILED Tuesday, August 07, 2007
APPL NO 11/835391
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/370
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776596 Badylak
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Stephen F. Badylak (West Lafayette, Indiana)
ABSTRACT A tissue graft construct for use in repairing diseased or damaged tissues is provided. The tissue graft construct comprises a matrix composition selected from the group consisting of urinary bladder submucosa and stomach submucosa, and extracts and hydrolysates thereof, added endothelial cells, and at least one additional preselected, exogenous population of cells which enhance initiation of the formation vessel-like structures in the graft construct. The preselected population of cells can be a population of non-keratinized or keratinized epithelial cells or a population of mesodermally-derived cells selected from the group consisting of fibroblasts, smooth muscle cells, skeletal muscle cells, cardiac muscle cells, multi-potential progenitor cells, pericytes, osteogenic cells, and any other suitable cell type, preferably selected based on the tissue to be repaired. Methods for enhancing the vascularization in vivo of these tissue graft constructs and for preparing these graft constructs are also provided.
FILED Friday, May 02, 2003
APPL NO 10/428358
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/373
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776600 Kumta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Prashant N. Kumta (Pittsburgh, Pennsylvania);  Charles Sfeir (Pittsburgh, Pennsylvania);  Jeffrey Owen Hollinger (Pittsburgh, Pennsylvania);  Daiwon Chol (Pittsburgh, Pennsylvania);  Lee Weiss (Pittsburgh, Pennsylvania);  Phil Campbell (Cranberry Township, Pennsylvania)
ABSTRACT Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
FILED Wednesday, June 13, 2007
APPL NO 11/811992
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776607 Gladyshev et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Vadim N. Gladyshev (Lincoln, Nebraska);  Dolph L. Hatfield (Washington, District of Columbia);  Kuan-Teh Jeang (Rockville, Maryland);  Alan Diamond (Naperville, Illinois);  John C. Wootton (Rockville, Maryland)
ABSTRACT A 15 kDa selenium-containing protein (“selenoprotein”) is disclosed. The protein is shown to be differentially expressed in cancer cells, such as prostate cancer cells. There is a correlation between the presence of a polymorphism at nucleotide positions 811 and 1125 of the 15 kDa selenoprotein gene, and the presence of cancer. This polymorphism is more prevalent in the African American population. The determination of an individual's genotype may be used as an indicator of the need for dietary selenium supplementation to inhibit tumor development. Compositions including the isolated protein, specific binding agents that recognize the protein, as well as underlying nucleic acid sequences are presented, as are methods of using such compositions.
FILED Monday, September 22, 2008
APPL NO 12/234968
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776613 Zhuang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Xiaowei Zhuang (Cambridge, Massachusetts);  Wilfred Mark Bates (Somerville, Massachusetts);  Michael J. Rust (Medford, Massachusetts)
ABSTRACT The present invention generally relates to sub-diffraction image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA or a protein. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction image resolution, computer programs and techniques for sub-diffraction image resolution, methods for promoting sub-diffraction image resolution, methods for producing photoswitchable entities, and the like.
FILED Wednesday, November 29, 2006
APPL NO 11/605842
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776817 Ford
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Morehouse School of Medicine (Atlanta, Georgia)
INVENTOR(S) Byron Ford (Atlanta, Georgia)
ABSTRACT Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke, inflammation or organophosphate neurotoxins. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain.
FILED Friday, September 01, 2006
APPL NO 11/514352
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776823 Gallo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard L. Gallo (San Diego, California);  Masamoto Murakami (Hokkaido, Japan)
ABSTRACT Provided are peptide and peptide consensus sequences, which inhibit bacterial growth and/or viral growth and mimic the activity of LL-37, CRAMP, and/or FALL-39. The peptides are useful as antimicrobials, anti-inflammatories and antiviral agents.
FILED Wednesday, October 20, 2004
APPL NO 10/575537
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776824 Barasch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University (New York, New York);  Children's Hospital Medical Center (Cincincati, Ohio)
INVENTOR(S) Jonathan M. Barasch (New York, New York);  Prasad Devarajan (Cincinnati, Ohio);  Kiyoshi Mori (New York, New York)
ABSTRACT Use of neutrophil gelatinase-associated lipocalin (NGAL) as a therapeutic and in a method of treating, reducing, or ameliorating an injury selected from an ischemic injury, an ischemic-reperfusion injury, and a toxin-induced injury, to an organ in a patient. The invention includes administering to the patient NGAL in an amount effective to treat, reduce or ameliorate ischemic, ischemic-reperfusion, or toxin-induced injury to the organ, such as the kidney. A siderophore can be co-administered with the NGAL. The invention also relates to administering a sideophore to enhance a response to secretion of NGAL following an ischemic or toxin-induced injury to an organ in a patient.
FILED Friday, May 06, 2005
APPL NO 11/123364
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776826 Vignery et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Unigene Laboratories, Inc. (Boonton, New Jersey);  Yale University (New Haven, Connecticut)
INVENTOR(S) Agnes Vignery (Branford, Connecticut);  Nozer M. Mehta (Randolph, New Jersey);  James P. Gilligan (Union, New Jersey)
ABSTRACT A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.
FILED Monday, March 31, 2008
APPL NO 12/059662
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776836 Sullenger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Bruce A. Sullenger (Durham, North Carolina);  Christopher P. Rusconi (Durham, North Carolina);  Rebekah R. White (Durham, North Carolina)
ABSTRACT RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed.
FILED Friday, October 26, 2007
APPL NO 11/925648
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776837 Sullenger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Bruce A. Sullenger (Durham, North Carolina);  Christopher P. Rusconi (Durham, North Carolina)
ABSTRACT RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed.
FILED Tuesday, November 06, 2007
APPL NO 11/936015
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776877 Charvat et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) ChemoCentryx, Inc. (Mountain View, California)
INVENTOR(S) Trevor T. Charvat (San Jose, California);  Cheng Hu (Menlo Park, California);  Anita Melikian (San Francisco, California);  Aaron Novack (San Jose, California);  Andrew M. K. Pennell (San Francisco, California);  Edward J. Sullivan (San Jose, California);  William D. Thomas (San Jose, California);  Solomon Ungashe (Fremont, California);  Penglie Zhang (Foster City, California);  Jay Powers (Pacifica, California);  Sreenivas Punna (Sunnyvale, California)
ABSTRACT Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
FILED Tuesday, June 17, 2008
APPL NO 12/140593
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776883 Di Santo et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Roberto Di Santo (Rome, Italy);  Yves Pommier (Bethesda, Maryland);  Christophe Marchand (Bethesda, Maryland);  Marino Artico (Rome, Italy);  Roberta Costi (Rome, Italy)
ABSTRACT Novel quinoline inhibitors of retroviral integrase, particularly HIV-1 integrase. The quinoline inhibitors are oxoquinolines that can be used for preventing or treating AIDS or HIV infection in a subject.
FILED Wednesday, March 09, 2005
APPL NO 10/591679
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/314
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776894 Ronai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Burnham Institute for Medical Research (La Jolla, California)
INVENTOR(S) Ze'ev A. Ronai (San Diego, California);  Anindita Bhoumik (San Diego, California);  Nicholas D. P. Cosford (San Diego, California);  Russell Dahl (Carlsbad, California)
ABSTRACT There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provided derivatives of celastrol and compositions comprising acetyl isogambogic acid, celastrol, or a derivative thereof.
FILED Friday, August 15, 2008
APPL NO 12/192753
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/357
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776908 Powis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents (Tucson, Arizona);  The University of Pittsburgh (Pittsburgh, Pennsylvania)
INVENTOR(S) Garth Powis (Houston, Texas);  Peter Wipf (Pittsburgh, Pennsylvania)
ABSTRACT Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well, as tumor formation in a subject are described herein.
FILED Thursday, September 20, 2007
APPL NO 11/858508
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/422
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776916 Freeman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama);  University of Oregon (Eugene, Oregon)
INVENTOR(S) Bruce A. Freeman (Pittsburgh, Pennsylvania);  Francisco Schopfer (Pittsburgh, Pennsylvania);  Valerie O'Donnell (Penarth, United Kingdom);  Paul Baker (Pittsburgh, Pennsylvania);  Yuqing E. Chen (Ann Arbor, Michigan);  Bruce Branchaud (Eugene, Oregon)
ABSTRACT Described herein are nitrated lipids and methods of making and using the nitrated lipids.
FILED Tuesday, April 26, 2005
APPL NO 11/568377
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/558
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777000 Gallo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard L. Gallo (San Diego, California);  Donald Y. M. Leung (Denver, Colorado);  James F. Jones (Decatur, Georgia)
ABSTRACT The disclosure provides methods and compositions useful in the treatment of dermatitis and viral infections. The compositions comprise cationic peptides of the cathelicidin family including LL-37, related homologues, and variants thereof.
FILED Friday, March 05, 2004
APPL NO 10/546739
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/324
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777001 Fasano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Alessio Fasano (West Friendship, Maryland);  Stefanie N. Vogel (Columbia, Maryland)
ABSTRACT Agonist polypeptide of a receptor protein has been identified. The agonist can be used to facilitate drug and antigen absorption. Suitable routes of administration include oral, nasal, transdermal, and intravenous. Pharmaceutical formulations may comprise a therapeutic agent or an immunogenic agent in combination with the agonist polypeptide.
FILED Friday, August 11, 2006
APPL NO 11/502490
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/329
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777005 Croce et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Thomas Jefferson University (Philadelphia, Pennsylvania)
INVENTOR(S) Carlo M Croce (Philadelphia, Pennsylvania);  Hideshi Ishii (Bryn Mawr, Pennsylvania)
ABSTRACT The invention relates to isolated polynucleotides homologous with a portion of one strand of the human tumor suppressor gene, FEZ1, and to the tumor suppressor protein encoded thereby, Fez1. The polynucleotides are useful, for example, as probes, primers, portions of expression vectors, and the like. The invention also includes diagnostic, therapeutic, cell proliferation enhancement, and screening methods which involve these polynucleotides and protein. The invention further includes kits useful for performing the methods of the invention.
FILED Tuesday, November 21, 2006
APPL NO 11/602656
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/352
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777016 Okumoto et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Non-Profit Organization (NPO)
Human Frontier Science Program (HFSP)
APPLICANT(S)
ASSIGNEE(S) Carnegie Institution of Washington (Washington, District of Columbia)
INVENTOR(S) Sakiko Okumoto (Washington, District of Columbia);  Loren L. Looger (Washington, District of Columbia);  Wolf B. Frommer (Washington, District of Columbia)
ABSTRACT Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture.
FILED Friday, October 14, 2005
APPL NO 11/665343
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777019 Pastan et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ira Pastan (Potomac, Maryland);  Giuliana Salvatore (Naples, Italy);  Richard Beers (Rockville, Maryland);  Robert J. Kreitman (Potomac, Maryland)
ABSTRACT Recombinant immunotoxins are fusion proteins composed of the Fv domains of antibodies fused to bacterial or plant toxins. RFB4 (Fv)-PE38 is an immunotoxin that targets CD22 expressed on B cells and B cell malignancies. The present invention provides antibodies and antibody fragments that have improved ability to bind the CD22 antigen of B cells and B cell malignancies compared to RFB4. Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells. Compositions that incorporate these antibodies into chimeric immunotoxin molecules that can be used in medicaments and methods for inhibiting the growth and proliferation of leukemia and lymphoma cells.
FILED Wednesday, February 13, 2008
APPL NO 12/030828
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.530
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777025 Schramm et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Albert Einstein College of Medicine of Yeshiva University (Bronx, New York);  Industrial Research Limited (Lower Hutt, New Zealand)
INVENTOR(S) Vern L. Schramm (New Rochelle, New York);  Richard Hubert Furneaux (Wellington, New Zealand);  Peter Charles Tyler (Wellington, New Zealand);  Gary Brian Evans (Lower Hutt, New Zealand)
ABSTRACT Improved transition state analog inhibitors of ricin toxin-A are provided. Methods of using those inhibitors to inhibit ricin toxin-A and to prevent the toxic effects of ricin toxin-A in a mammal are also provided.
FILED Thursday, September 09, 2004
APPL NO 10/570673
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/27.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777029 Grotjahn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) San Diego State University (SDSU) Foundation (San Diego, California)
INVENTOR(S) Douglas Grotjahn (San Diego, California);  Erik Wiener (Pittsburgh, Pennsylvania)
ABSTRACT The present invention relates to a method for preparing a bifunctional chelator for lanthanide. The method comprises the steps of providing a starting material which has an amino and carboxyl group; protecting the amino with an amino protecting group and the carboxyl with a carboxyl protecting group to produce a protected compound; reacting the protected compound with cyclen to generate a monoalkylated cyclen; reacting the monoalkylated cyclone with an activated compound to generated tetra-alkylated cyclone; removing the amino protecting group with a first protecting group removal reagent; and removing the carboxyl protecting groups with a second protecting group removal reagent to yield a bifunctional chelator having three more carboxyl groups and one or more amino groups.
FILED Wednesday, May 02, 2007
APPL NO 11/743654
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
540/474
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777392 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Shih-Chi Chen (Boston, Massachusetts);  Martin L. Culpepper (Danvers, Massachusetts)
ABSTRACT A thermomechanical actuation system and method includes an elongated thermomechanical actuator (TMA), which is contoured so that electrical resistance at a mid-portion of the TMA is less than at end portions thereof. A pulse generator is electrically coupled to the TMA, and is configured to supply excitation pulses to the TMA. The excitation pulses are transient, so that each pulse is terminated prior to reaching a steady state amplitude, while having sufficient energy to heat the TMA to its predetermined operational temperature range.
FILED Thursday, November 08, 2007
APPL NO 11/937224
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/306
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777484 Garwood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (St. Paul, Minnesota)
INVENTOR(S) Michael Garwood (Medina, Minnesota);  Djaudat S. Idiyatullin (Minneapolis, Minnesota);  Curt Corum (Shoreview, Minnesota);  Steen Moeller (Golden Valley, Minnesota)
ABSTRACT A method of magnetic resonance is provided that uses a frequency swept excitation wherein the acquired signal is a time domain signal is provided. In one embodiment, the method comprises, applying a sweeping frequency excitation and acquiring a time domain signal. The sweeping frequency excitation has a duration and is configured to sequentially excite isochromats having different resonant frequencies. Acquisition of the time domain signal is done during the duration of the sweeping frequency excitation. The time domain signal is based on evolution of the isochromats.
FILED Monday, September 15, 2008
APPL NO 12/210342
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/307
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777486 Hargreaves et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Brian Hargreaves (Menlo Park, California);  Wenmiao Lu (Palo Alto, California)
ABSTRACT A method for magnetic resonance imaging (MRI) is provided. A magnetic resonance excitation is provided. A plurality of k-space echoes is acquired bi-directionally wherein at least one echo is an even echo acquired in a first direction and at least one echo is an odd echo acquired in a second direction opposite from the first direction. K-space echo realignment is corrected between the even and odd echoes. Field inhomogeneity induced artifacts are corrected. Chemical shift induced artifacts between at least two species are corrected.
FILED Thursday, September 13, 2007
APPL NO 11/854687
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777487 Ying et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Lei Ying (Kenosha, Wisconsin);  Jinhua Sheng (Chicago, Illinois)
ABSTRACT A method of parallel magnetic resonance imaging (pMRI) comprising acquiring pMRI signals simultaneously through a plurality of receiving coils, wherein each coil has a localized sensitivity with respect to an imaged volume; jointly estimating values for the imaged volume and for a sensitivity function for at least one of the plurality of receiving coils; and transmitting the reconstructed image to a device.
FILED Friday, February 15, 2008
APPL NO 12/032155
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778386 Yin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York);  The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Zhye Yin (Schenectady, New York);  Jed Douglas Pack (Glenville, New York);  Bruno K. B. De Man (Clifton Park, New York);  Norbert J. Pelc (Los Altos, California)
ABSTRACT Disclosed are embodiments of methods for reconstructing x-ray projection data (e.g., one or more sinograms) acquired using a multi-source, inverse-geometry computed tomography (“IGCT”) scanner. One embodiment of a first method processes an IGCT sinogram by rebinning first in “z” and then in “xy,” with feathering applied during the “xy” rebinning. This produces an equivalent of a multi-axial 3rd generation sinogram, which may be further processed using a parallel derivative and/or Hilbert transform. A TOM-window (with feathering) technique and a combines backprojection technique may also be applied to produce a reconstructed volume. An embodiment of a second method processes an IGCT sinogram using a parallel derivative and/or redundancy weighting. The second method may also use signum weighting, TOM-windowing (with feathering), backprojection, and a Hilbert Inversion to produce another reconstructed volume.
FILED Friday, April 27, 2007
APPL NO 11/741359
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778691 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Tiezhi Zhang (Madison, Wisconsin);  Bhudatt R. Paliwal (Madison, Wisconsin)
ABSTRACT Radiation treatment of the lung or surrounding tissue during continuous breathing is made possible by preparing a treatment plan linked to motion phase and then synchronizing the plan to motion phase as the patient follows a regular breathing schedule.
FILED Thursday, November 06, 2003
APPL NO 10/702810
ART UNIT 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Surgery
6/427
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778693 Barbour et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Randall L. Barbour (Glen Head, New York);  Yaling Pei (Morris Plains, New Jersey)
ABSTRACT A time series of optical tomography data is obtained for a target tissue site in a human (or animal), using an optical wavelength, such as near infrared, at which hemoglobin is absorptive, to observe properties of the vasculature of the human. The data may be compared to baseline data of a corresponding tissue site, e.g., from a healthy human, or from another, corresponding tissue site of the human. For example, a suspected cancerous breast of a human may be compared to a known healthy breast to detect differences in the vasculature. Measures may be made of flow, oxygen supply/demand imbalance, and evidence of altered regulation of the peripheral effector mechanism. The function of the target tissue site may be analyzed, along with the coordinated interaction between multiple sites of the target system. A provocation may be administered to identify surrogate markers of an underlying state or process.
FILED Monday, April 07, 2003
APPL NO 10/408510
ART UNIT 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Surgery
6/473
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 07774912 Gordon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Touchstone Research Laboratory, Ltd. (Triadelphia, West Virginia)
INVENTOR(S) Brian L. Gordon (Wheeling, West Virginia);  Gregg W. Wolfe (Wheeling, West Virginia)
ABSTRACT Metal matrix composites having open or closed channels extending longitudinal through the length of the composite as well as methods and apparatus for forming the same are described. The shaped metal matrix composites are made of continuous fiber reinforced metal matrix composite materials. They have an integrally formed, non-cast, metal matrix composite body portion where the walls have a substantially uniform distribution of continuous fibers in a matrix metal throughout the volume of the walls and have at least one channel extending through the body of the shaped metal matrix composite.
FILED Wednesday, November 24, 2004
APPL NO 10/995279
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Metal working
029/419.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07774913 Murdy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Richard M. Murdy (Bedford, Indiana);  John C. Simmons (Koleen, Indiana);  James R. Blake (Washington, Indiana);  Timothy L. Barrett (Solsberry, Indiana)
ABSTRACT A device for separating opposed ceramic elements from a metal base member, the device including a rigid body shaped complementarily to an inside surface of the base member and receivable therein. Opposed wedge members are mounted are in the body wall. The body includes a threaded interior surface. A bolt is included for threaded engagement with the interior surface and has a conically-shaped end. Each wedge member is engageable with one of the ceramic elements, such that upon inserting of the body in the base member and threaded movement of the bolt inward to the body, the end of the bolt engages the wedge members to urge the wedge members outward through a body wall to engage the ceramic elements to urge the ceramic elements apart and to separate from the base member.
FILED Friday, September 08, 2006
APPL NO 11/518739
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/426.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07774920 Deng et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Tao Deng (Niskayuna, New York);  Francisco Arias (Mason, Ohio);  Rustem F. Ismagilov (Chicago, Illinois);  Paul J. A. Kenis (Champaign, Illinois);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A method of forming microstructures. An article including a metal atom precursor is disproportionally exposed to electromagnetic radiation in an amount and intensity sufficient to convert some of the precursor to elemental metal. Additional conductive material may then be deposited onto the elemental metal to produce a microstructure.
FILED Wednesday, April 25, 2007
APPL NO 11/789622
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/527.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775053 Joe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Christopher R. Joe (Wethersfield, Connecticut);  Paul M. Lutjen (Kennebunkport, Maine)
ABSTRACT A compact heat exchanger pedestal array for augmenting heat transfer in a machine is disclosed. The compact heat exchanger pedestal array includes a wall having first and second surfaces. The first surface faces a heated flow path and the second surface partially forms a flow path for cooling fluid. A plurality of pedestals extend from the second surface of the wall. At least one turbulator strip extends between adjacent pedestals. The turbulator strips and pedestals are operable for mixing the cooling fluid to increase heat transfer from the wall to the cooling fluid.
FILED Monday, September 20, 2004
APPL NO 10/945477
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/806
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775146 Bitar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) Xtreme ADS Limited (Anderson, Indiana)
INVENTOR(S) Peter Victor Bitar (Anderson, Indiana);  Ricky Lee Busby (Anderson, Indiana);  Leroy Ernest Lakey (Anderson, Indiana);  Varce Eron Howe (Zionsville, Indiana)
ABSTRACT Disclosed is a system and method for neutralizing explosives and electronics utilizing a high voltage electrical discharge.
FILED Tuesday, February 12, 2008
APPL NO 12/030144
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/1.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775174 Humphreys et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Vehicle Control Technologies, Inc. (Reston, Virginia)
INVENTOR(S) Douglas E. Humphreys (Great Falls, Virginia);  Ryan D. Schulz (Reston, Virginia);  Alexander V. Roup (Sterling, Virginia);  Neill S. Smith (Springfield, Virginia);  Daniel N. Dietz (Alexandria, Virginia)
ABSTRACT An at least partially self-propelled vehicle is configured for being towed by a towing vehicle, by way of a tow line. Operation of the vehicles may be coordinated so that, for a length of the tow line that connects the vehicles, the length of the tow line is curved in a manner that inhibits the tow line from transferring oscillatory motion between the vehicles while the entirety of the length of the tow line may be under tension.
FILED Friday, August 29, 2008
APPL NO 12/231238
ART UNIT 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships
114/244
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775770 Carbaugh
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aviation and Missile Life Cycle Management Command (AMCOM)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Steven R. Carbaugh (Glen Mills, Pennsylvania)
ABSTRACT A flexible, resilient seal protects a bearing in a pitch joint of a helicopter blade assembly from contaminants. The seal includes a flexible, resilient body having a first end bonded to a stationary portion of the joint, and a second end biased into sealing engagement with a displaceable portion of the joint. The body includes an intermediate bellows section surrounding the bearing that expands and contracts to accommodate displacement between the stationary and movable portions of the joint. The second end of the seal includes a lip that rubs on a sacrificial wear layer formed on the second portion of the joint.
FILED Thursday, December 21, 2006
APPL NO 11/643318
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/155
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775833 Le et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) Williams Pyro, Inc. (Fort Worth, Texas)
INVENTOR(S) Kevin D. Le (Richland Hills, Texas);  Ricardo Ramirez (Fort Worth, Texas);  Kisoo Jung (Irving, Texas)
ABSTRACT The high speed intelligent cable provided herein is multifunctional, lightweight, flexible and re-configurable. The cable assembly includes a low profile ribbon cable of multiple conductors. Built-in health indicators provide user assessment of, for example, connectivity. Active electronics and embedded intelligent firmware provide various functions, to include built-in test performance capability. Ready cable reconfiguration for system integration, or for other needs, is facilitated by logic and switching circuitry. Still further, built-in automatic multi-functional cable testing may include automatic reconfiguration. Testing and reconfiguration can be remotely activated. The cable described herein can reduce time and manhours needed for testing, installation, and maintenance. The lightweight multi-functional cable makes a positive contribution to the function/mass payload ratio in complex and mass-sensitive applications.
FILED Friday, June 27, 2008
APPL NO 12/163507
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrical connectors
439/620.80
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776021 Borenstein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The Charles Stark Draper Laboratory (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Jeffrey T. Borenstein (Holliston, Massachusetts);  Eli Weinberg (Needham, Massachusetts);  Brian K. Orrick (Cambridge, Massachusetts);  Eleanor M. Pritchard (Cambridge, Massachusetts);  Edward J. Barnard (Cambridge, Massachusetts);  Nicholas J. Krebs (Boston, Massachusetts);  Theodore Marentis (Boston, Massachusetts);  Joseph P. Vacanti (Boston, Massachusetts);  Mohammad Reza Kaazempur-Mofrad (Cambridge, Massachusetts)
ABSTRACT Methods and materials for making an apparatus which duplicates the functionality of a physiological system id provided.
FILED Friday, November 05, 2004
APPL NO 10/983213
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Surgery
64/406
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776130 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Can Xue (Evanston, Illinois)
ABSTRACT Silver nanoprisms having a unimodal size distribution are disclosed. The size of the nanoprisms can be controlled by adjusting the pH during irradiation of silver nanocrystals.
FILED Monday, June 18, 2007
APPL NO 11/820087
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/345
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776153 Schowalter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Missile Defense Agency (MDA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Crystal IS, Inc. (Green Island, New York)
INVENTOR(S) Leo J. Schowalter (Latham, New York);  Glen A. Slack (Scotia, New York);  J. Carlos Rojo (East Setauket, New York)
ABSTRACT A method and apparatus for producing bulk single crystals of AlN having low dislocation densities of about 10,000 cm−2 or less includes a crystal growth enclosure with Al and N2 source material therein, capable of forming bulk crystals. The apparatus maintains the N2 partial pressure at greater than stoichiometric pressure relative to the Al within the crystal growth enclosure, while maintaining the total vapor pressure in the crystal growth enclosure at super-atmospheric pressure. At least one nucleation site is provided in the crystal growth enclosure, and provision is made for cooling the nucleation site relative to other locations in the crystal growth enclosure. The Al and N2 vapor is then deposited to grow single crystalline low dislocation density AlN at the nucleation site. High efficiency ultraviolet light emitting diodes and ultraviolet laser diodes are fabricated on low defect density AlN substrates, which are cut from the low dislocation density AlN crystals. Bulk crystals of ZnO may also be produced using the method.
FILED Thursday, November 03, 2005
APPL NO 11/265909
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/81
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776207 Abhari et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Syntroleum Corporation (Tulsa, Oklahoma)
INVENTOR(S) Ramin Abhari (Bixby, Oklahoma);  Paul Ahner (Tulsa, Oklahoma)
ABSTRACT A process for producing alkyl aromatic middle distillate fuels is described. The process includes (a) catalytically converting paraffinic naphtha to a composition containing benzene and olefins; (b) processing the olefin/benzene composition in an aromatic alkylation reactor to produce alkyl-benzene components (c) separating the alkyl aromatics from the unconverted naphtha; and (d) optionally recycling the unconverted paraffinic naphtha to the dehydrogenation/amortization reactor of step a.
FILED Friday, October 05, 2007
APPL NO 11/868059
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Mineral oils: Processes and products
28/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776233 Arafat et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) El Sayed Arafat (Leonardtown, Maryland);  Judy Butler-Kowalik (Hollywood, Maryland);  Kenneth Clark (Chalfont, Pennsylvania);  David L. Gauntt (Chestertown, Maryland)
ABSTRACT The invention relates to an oleaginous corrosion-inhibiting composition, and the use of said composition to protect metal from corrosion. The composition comprises, in parts by weight, from about 20 to 60 parts of lubricating oil, 10 to 40 parts of organic solvent, 20 to 60 parts of corrosion-inhibitor consisting of a sulfonic acid-carboxylic acid metal complex or a mixture of said metal complex with a small but effective amount of an oil soluble alkyl phosphate, from 0.1 to 2.0 parts of an oil soluble antioxidant, from 0.1 to 5.0 parts of a water-displacing compound and from 0.0 to 1.0 part of a metal deactivator.
FILED Thursday, October 27, 2005
APPL NO 11/264336
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/395
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776235 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Milko E. van der Boom (Evanston, Illinois)
ABSTRACT The preparation of robust, thin film materials with large second-order optical nonlinearities through the covalent self-assembly of chromophoric compositions and innovative use of silyl chemistry.
FILED Tuesday, January 13, 2009
APPL NO 12/352792
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/582
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776269 Snow et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Eric S. Snow (Springfield, Virginia);  F. Keith Perkins (Alexandria, Virginia);  Eric Houser (Nokesville, Virginia);  Stan V. Stepnowski (Alexandria, Virginia);  R. Andrew McGill (Lorton, Virginia)
ABSTRACT A sensing device having: a bottom electrode, a dielectric on the bottom electrode, a grid of nanoelectrodes on the dielectric, and a top electrode in electrical contact with the grid. A method of chemical or biological sensing comprising: providing a grid of nanoelectrodes; exposing the grid to fluid suspected of containing a chemical or biological analyte; and measuring a change in the capacitance and conductance of the grid.
FILED Tuesday, September 27, 2005
APPL NO 11/239430
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/82.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776303 Hung et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) PPG Industries Ohio, Inc. (Cleveland, Ohio)
INVENTOR(S) Cheng-Hung Hung (Wexford, Pennsylvania);  Noel R. Vanier (Wexford, Pennsylvania)
ABSTRACT The production of ultrafine metal carbide powders from polymeric powder and metallic precursor powder starting materials is disclosed. In certain embodiments, the polymeric powder may comprise polypropylene, polyethylene, polystyrene, polyester, polybutylene, nylon, polymethylpentene and the like. The metal precursor powder may comprise pure metals, metal alloys, intermetallics and/or metal-containing compounds such as metal oxides and nitrides. In one embodiment, the metal precursor powder comprises a silicon-containing material, and the ultrafine powders comprise SiC. The polymeric and metal precursor powders are fed together or separately to a plasma system where the feed materials react to form metal carbides in the form of ultrafine particles.
FILED Wednesday, August 30, 2006
APPL NO 11/468430
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/291
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US 07776444 Rinzler et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Andrew G. Rinzler (Newberry, Florida);  Zhihong Chen (Gainesville, Florida)
ABSTRACT An optically transparent and electrically conductive single walled carbon nanotube (SWNT) film comprises a plurality of interpenetrated single walled carbon nanotubes, wherein for a 100 nm film the film has sufficient interpenetration to provide a 25° C. sheet resistance of less than 200 ohm/sq. The film also provides at least 20% optical transmission throughout a wavelength range from 0.4 μm to 5 μm.
FILED Thursday, October 19, 2006
APPL NO 11/583545
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Stock material or miscellaneous articles
428/408
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US 07776548 Rajasekaran
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ayyappan K. Rajasekaran (Los Angeles, California)
ABSTRACT A chimeric transmembrane protein comprising a membrane-spanning polypeptide and an internalization motif of the sequence MXXXL, where X is any amino acid. The chimeric protein can be expressed on the surface of a cell and internalized. Polynucleotides and expression vectors encoding chimeric transmembrane proteins are also provided. Expression of chimeric proteins in the plasma membrane of target cells, followed by binding of antibodies to the chimeric proteins, where the antibodies are conjugated to a cytotoxic agent, provides a means to deliver the cytotoxic agent to the inside of the target cells.
FILED Friday, September 30, 2005
APPL NO 11/241416
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776600 Kumta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Prashant N. Kumta (Pittsburgh, Pennsylvania);  Charles Sfeir (Pittsburgh, Pennsylvania);  Jeffrey Owen Hollinger (Pittsburgh, Pennsylvania);  Daiwon Chol (Pittsburgh, Pennsylvania);  Lee Weiss (Pittsburgh, Pennsylvania);  Phil Campbell (Cranberry Township, Pennsylvania)
ABSTRACT Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
FILED Wednesday, June 13, 2007
APPL NO 11/811992
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776613 Zhuang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Xiaowei Zhuang (Cambridge, Massachusetts);  Wilfred Mark Bates (Somerville, Massachusetts);  Michael J. Rust (Medford, Massachusetts)
ABSTRACT The present invention generally relates to sub-diffraction image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA or a protein. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction image resolution, computer programs and techniques for sub-diffraction image resolution, methods for promoting sub-diffraction image resolution, methods for producing photoswitchable entities, and the like.
FILED Wednesday, November 29, 2006
APPL NO 11/605842
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Analytical and immunological testing
436/172
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US 07776642 Eriksson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Mark A. Eriksson (Madison, Wisconsin);  Max G. Lagally (Madison, Wisconsin);  Arnold Melvin Kiefer (Madison, Wisconsin)
ABSTRACT A quantum-well photoelectric device, such as a quantum cascade laser, is constructed of monocrystalline nanoscale membranes physically removed from a substrate and mechanically assembled into a stack.
FILED Thursday, May 15, 2008
APPL NO 12/120933
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/74
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776661 Qin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Hua Qin (Madison, Wisconsin);  Hyun Seok Kim (Madison, Wisconsin);  Robert H. Blick (Madison, Wisconsin)
ABSTRACT A co-planar waveguide structure is integrated with an upwardly extending resonant pillar to produce transfer cells that provide controlled transmission of electricity between adjacent structures of the co-planar waveguide in order to produce easily fabricated electronic devices operating at megahertz and gigahertz speeds for filtration, modulation, rectification, and mixing of high-frequency signals.
FILED Wednesday, July 11, 2007
APPL NO 11/776254
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/144
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777180 Hill, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) Washington State University Research Foundation (Pullman, Washington)
INVENTOR(S) Herbert Henderson Hill, Jr. (Pullman, Washington);  Maggie Tam (Pullman, Washington)
ABSTRACT The invention includes an ion mobility spectrometer having a liquid filled drift chamber. The chamber has an ionization region partitioned from and an ion separation region by a reversible ion-migration block. An electrical field within the chamber allows ions to migrate toward the electrode collector. Passage of ions from the ionization region is triggered by reversing the block allowing ions to migrate into the ion separation region. The invention includes a method of ion mobility analysis in liquid phase. Ions are mobilized to migrate through a drift liquid and are detected at an end of a drift chamber. The invention also includes a method of generating ions in a sample. A sample containing molecules in a first solvent is introduced into a second solvent through a charged capillary where the electrically charged sample is electro-disperses to ionize the molecules.
FILED Tuesday, July 15, 2008
APPL NO 12/173750
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/286
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US 07777188 Fest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Eric Fest (Tucson, Arizona);  Rex Kremer (Tucson, Arizona)
ABSTRACT The disclosed system and apparatus for a sensor support structure generally includes a substantially reflective support strut having discontinuous protrusions on the support surface presented to the field of view of the sensor. These discontinuous protrusions may be suitably configured such that ambient thermal radiation is generally reflected away from the support strut and divergent from acceptance in the sensor's optical train.
FILED Tuesday, February 27, 2007
APPL NO 11/679490
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/353
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777217 Preble et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) Kyma Technologies, Inc. (Raleigh, North Carolina)
INVENTOR(S) Edward A. Preble (Raleigh, North Carolina);  Denis Tsvetkov (Morrisville, North Carolina);  Andrew D. Hanser (Raleigh, North Carolina);  N. Mark Williams (Raleigh, North Carolina);  Xueping Xu (Stamford, Connecticut)
ABSTRACT In a method for making an inclusion-free uniformly semi-insulating GaN crystal, an epitaxial nitride layer is deposited on a substrate. A 3D nucleation GaN layer is grown on the epitaxial nitride layer by HVPE under a substantially 3D growth mode, wherein a surface of the nucleation layer is substantially covered with pits and the aspect ratio of the pits is essentially the same. A GaN transitional layer is grown on the nucleation layer by HVPE under a condition that changes the growth mode from the substantially 3D growth mode to a substantially 2D growth mode. After growing the transitional layer, a surface of the transitional layer is substantially pit-free. A bulk GaN layer is grown on the transitional layer by HVPE. After growing the bulk layer, a surface of the bulk layer is smooth and substantially pit-free. The GaN is doped with a transition metal during at least one of the foregoing GaN growth steps.
FILED Thursday, November 30, 2006
APPL NO 11/606633
ART UNIT 2823 — Optics
CURRENT CPC
Active solid-state devices
257/21
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777241 Moustakas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Theodore D. Moustakas (Dover, Massachusetts);  Jasper S. Cabalu (Allston, Massachusetts)
ABSTRACT A semiconductor sensor, solar cell or emitter or a precursor therefore having a substrate and textured semiconductor layer deposited onto the substrate. The layer can be textured as grown on the substrate or textured by replicating a textured substrate surface. The substrate or first layer is then a template for growing and texturing other semiconductor layers from the device. The textured layers are replicated to the surface from the substrate to enhance light extraction or light absorption. Multiple quantum wells, comprising several barrier and quantum well layers, are deposited as alternating textured layers. The texturing in the region of the quantum well layers greatly enhances internal quantum efficiency if the semiconductor is polar and the quantum wells are grown along the polar direction. This is the case in nitride semiconductors grown along the polar [0001] or [000-1] directions.
FILED Friday, April 15, 2005
APPL NO 11/107150
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/95
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777318 Tornquist Hennig et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Los Angeles, California)
INVENTOR(S) Kelly Jill Tornquist Hennig (Torrance, California);  Patty Pei-Ling Chang-Chien (Redondo Beach, California);  Xianglin Zeng (Monterey Park, California);  Jeffrey Ming-Jer Yang (Cerritos, California)
ABSTRACT A wafer-level package that employs one or more integrated hydrogen getters within the wafer-level package on a substrate wafer or a cover wafer. The hydrogen getters are provided between and among the integrated circuits on the substrate wafer or the cover wafer, and are deposited during the integrated circuit fabrication process. In one non-limiting embodiment, the substrate wafer is a group III-V semiconductor material, and the hydrogen getter includes a titanium layer, a nickel layer, and a palladium layer.
FILED Tuesday, July 24, 2007
APPL NO 11/782460
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/682
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777496 Evans et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) James A. Evans (Tallulah, Louisiana);  Joseph B. Dunbar (Vicksburg, Mississippi);  George L. Mason (Vicksburg, Mississippi);  Richard W. Haskins (Raymond, Mississippi)
ABSTRACT A system and associated method permit remote monitoring of subsurface structure for purposes of early detection and location of hidden anomalies, e.g., water seepage in levees. Anomalies may be due to sand boils or displacement of underlying soil. Representative systems provide continuous monitoring via two complementary means: parallel pairs of ported (leaky) coaxial cables and a fiber optic cable, each pair of coaxial cables associated with a fiber optic cable. A fiber optic system, with associated light source, processor and display, together with an RF system, provides data to a remote location via telemetry or cellular phone, or both. The fiber optic cable(s) allow monitoring of displacement and vibrations within the structure. The ported coaxial cables, with associated RF source, using the same processor, display and telemetry used with the fiber optic sub-system, provide data for monitoring moisture change correlated to changes in the dielectric constant of surrounding material.
FILED Friday, July 18, 2008
APPL NO 12/175645
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/534
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US 07777505 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Henry S. White (Salt Lake City, Utah);  Ryan J. White (Salt Lake City, Utah);  Eric N. Ervin (Salt Lake City, Utah)
ABSTRACT A nanopore device includes a membrane having a nanopore extending there through forming a channel from a first side of the membrane to a second side of the membrane. The surface of the channel and first side of the membrane are modified with a hydrophobic coating. A first lipid monolayer is deposited on the first side of the membrane, and a second lipid monolayer is deposited on the second side of the membrane, wherein the hydrophobic coating causes spontaneous generation of a lipid bilayer across the nanopore orifice. Sensing entities, such as a protein ion channel, can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages, while resistance or current flow through the sensing entity can be measured electrically.
FILED Wednesday, May 02, 2007
APPL NO 11/743472
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/693
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777535 In et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Visarath In (Chula Vista, California);  Patrick Longhini (San Diego, California);  Yong (Andy) An Kho (Chula Vista, California);  Joseph D. Neff (San Diego, California);  Adi R. Bulsara (San Diego, California)
ABSTRACT In various embodiments, an apparatus for down-converting a first signal having a first frequency to a lower frequency is disclosed. The apparatus can include one or more arrays of N over-damped, bi-stable circuits unidirectionally-coupled from element to element.
FILED Thursday, May 22, 2008
APPL NO 12/125397
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Miscellaneous active electrical nonlinear devices, circuits, and systems
327/117
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777667 Rankin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of the Air Force (Washington, District of Columbia)
INVENTOR(S) Peter M. Rankin (Syracuse, New York);  Zenn Zenon (Syracuse, New York)
ABSTRACT A radar target identification apparatus utilizing a pseudo-random digital code to modulate a target's return signal to include a two-dimensional range and cross range Doppler-coded return with a target's skin return and thereby identify friendly targets to the interrogating radar unit.
FILED Wednesday, December 05, 1979
APPL NO 06/101401
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/45
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777877 Walker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Christopher I. Walker (Pasadena, California);  Axel Scherer (Laguna Beach, California)
ABSTRACT The invention provides a high efficiency coupling structure for extracting illumination such as fluorescent radiation from a chemical reaction vessel such as a cuvette. The cuvette is provided with a mirrored surface. An end cap for the cuvette includes a probe portion that exhibits total internal reflection. Lenses are provided in various embodiments that improve the light collection and directing properties of the end cap. A fast optical system for free space coupling of optical radiation emanating from a chemical processing cuvette that uses the end cap as an element is also described.
FILED Monday, October 22, 2007
APPL NO 11/876211
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/246
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777889 Qiu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Tiequn Qiu (Glendale, Arizona);  Steven J. Sanders (Scottsdale, Arizona);  Sorin Mosor (Peoria, Arizona);  Glen A. Sanders (Scottsdale, Arizona)
ABSTRACT A computer-implementable method of reducing bias instability in a fiber optic gyroscope includes receiving, with a computer, a first data set enabling the computer to generate a model of the gyroscope, including a light source, a photodetector, and a plurality of optical components and fiber sections coupling the light source to the photodetector, and a light signal to be propagated from the light source to the photodetector. The light signal has an associated wavelength spectrum. For each wavelength of the spectrum, the relative lightwave intensity reaching the photodetector is calculated. A signal-wave intensity and a spurious-wave intensity are determined from the calculated relative lightwave intensities. A scale factor is determined from the signal-wave intensity. The spurious-wave intensity is integrated over the wavelength spectrum of the light source to obtain a total spurious-wave intensity. A rate bias error is determined based on the total spurious-wave intensity and the scale factor.
FILED Thursday, August 07, 2008
APPL NO 12/187932
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/460
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778111 Hawkinson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Wesley J. Hawkinson (Chanhassen, Minnesota);  Kevin Sweeney (Minneapolis, Minnesota);  Randolph G. Hartman (Plymouth, Minnesota)
ABSTRACT A method for navigating underwater is disclosed. The method uses a navigation system to project a first velocity measurement along one or more signal beams having a second velocity measurement, where the second velocity measurement is related to at least one of the one or more signal beams. The method determines a position and location of an object associated with the navigation system based on a prediction of at least the second velocity measurement, and the navigation system is adjusted to perform within a prescribed measurement range based on a covariance of the first and second velocity measurements. The performance adjustments made in determining the position and location of the object are operable independent of the navigation system maintaining each of the signal beams due to one or more external environmental conditions.
FILED Wednesday, March 19, 2008
APPL NO 12/051740
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/89
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778183 Fan et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Jinliang Fan (Redmond, Washington);  Nagui Halim (Yorktown Heights, New York);  Zhen Liu (Tarrytown, New York);  Dimitrios Pendarakis (Westport, Connecticut)
ABSTRACT A method is provided for selecting a replication node from eligible nodes in a network. A multidimensional model is constructed that defines a multidimensional space and includes the eligible nodes, with each of the dimensions of the multidimensional model being a system characteristic. A data availability value is determined for each of the eligible nodes, and a cost of deploying is determined for each of at least two availability strategies to the eligible nodes. At least one of the eligible nodes is selected for replication of data that is stored on a source node in the network. The selecting step includes selecting the eligible node whose: data availability value is determined to be highest among the eligible nodes whose cost of deploying does not exceed a specified maximum, or cost of deploying is determined to be lowest among the eligible nodes whose data availability value does not exceed a specified minimum.
FILED Tuesday, February 20, 2007
APPL NO 11/676631
ART UNIT 2471 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/238
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778296 Vuckovic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Jelena Vuckovic (Palo Alto, California);  Ilya Fushman (Palo Alto, California);  Dirk Robert Englund (Stanford, California)
ABSTRACT Optical microcavity arrangements and approaches facilitate a variety of applications. According to an example embodiment of the present invention, an optical microcavity arrangement includes a microcrystal structure having a plurality of optical cavities therein to facilitate the control of light. Emitters such as colloidal quantum dots are optically coupled to the optical cavities by attaching or otherwise arranging a material, which includes the emitters, to the optical microcavity arrangement. In many applications, the emitters couple photons of a wavelength in a range of wavelengths selectively passed by the optical cavities, and are amenable to operation at relatively high temperatures (e.g., at about room temperature or higher), which is useful for a variety of applications.
FILED Friday, May 11, 2007
APPL NO 11/747721
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778493 Ho et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. (Rockville, Maryland)
INVENTOR(S) Vincent B. Ho (North Bethesda, Maryland);  Micah D. Schmidt (San Antonio, Texas)
ABSTRACT Methods for improving spatial and/or temporal resolution of digital images and for improving image data transmission by a novel technique—back pixelation, which involves data processing and reconstruction of overlaid images from multiple acquisition or multiple sampling. The back pixelation technique may be used for image data acquisition and transmission; it may be applied prospectively or retrospectively. In particular, the methods of this invention may be used in reducing the pixel size of a two-dimensional image or the voxel size of a three dimensional image; producing a two- or three-dimensional image from a multiplicity of images acquired from an object which are capable of overlaying one another by an increment; producing and transmitting a two- or three-dimensional image by multiple acquisitions according to an acquisition matrix; or transmitting a two- or three-dimensional image by reducing or decomposing the image to a plurality of image data packets and transmitting the same. The multiple acquisitions may be arranged by a predetermined temporal schedule. These methods may be advantageously applied in medical imaging, movies and video games, teleimage, and any other areas that involve digital image acquisition, processing, and transmission.
FILED Thursday, October 09, 2003
APPL NO 10/686194
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/299
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778547 Menendez
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Telcordia Technologies, Inc. (Piscataway, New Jersey)
INVENTOR(S) Ronald Charles Menendez (Chatham, New Jersey)
ABSTRACT The invention is directed to code labeling in an optical network. The network includes a transmitting station operable to transmit an optical signal. The network also includes an encoder coupled to the transmitting station operable to label the optical signal composed of a group of codes. A receiving station operable to receive the labeled group of optical codes is also provided. The receiving station is operable to read the optical signal if the label of the received group of codes corresponds to the group of codes assigned to the receiving station.
FILED Thursday, June 01, 2006
APPL NO 11/444764
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/77
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778948 Johnson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) W. Lewis Johnson (Venice, California);  Hannes Högni Vilhjálmsson (Reykjavik, Iceland)
ABSTRACT A character programming and control system and method for programming and controlling a virtual character during a social simulation, a character programming method for programming the actions of a virtual character, and a system and method for developing social skills of a user.
FILED Wednesday, October 18, 2006
APPL NO 11/550757
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/45
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779013 Chi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S) Ed H. Chi (Palo Alto, California);  William S. Liu (Cupertino, California)
ABSTRACT A system and method for determining a quantitative measure of search efficiency of related Web pages. An information goal is specified. A target Web page is identified within a plurality of Web pages. The information goal is searched via a search function in the Web pages to identify potential Web pages that include at least one hyperlink referencing and proximal cues relating to distal content included in another potential Web page. An activation network is formed. A directed graph is built, including nodes corresponding to the potential Web pages and arcs corresponding to the hyperlinks. A weight is assigned to each arc to represent a probability of traversal of the corresponding hyperlink based on a relatedness of keywords in the information goal to the proximal cues. A traversal through the activation network to the node corresponding to the target Web page is evaluated as a quantitative measure of search efficiency.
FILED Friday, November 04, 2005
APPL NO 11/267004
ART UNIT 2159 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/748
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779025 Gunawardena et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jamila Gunawardena (Palo Alto, California);  Jacques Reifman (New Market, Maryland)
ABSTRACT The present invention is directed to a system and method for providing researchers with a computer-assisted tool to evaluate, over a communications network, large electronic data sets stored on a remote server. The system allows the centralization of multiple data manipulation and analysis software modules co-located with the large data sets to reduce the amount of data from the data sets and software that has to be downloaded to a particular user's client computer. The system is designed to accommodate multiple researchers located at different geographic locations each of whom may have, with regard to the data, different scientific research objectives.
FILED Monday, December 12, 2005
APPL NO 11/298606
ART UNIT 2166 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/766
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779148 Arimilli et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lakshminarayana B. Arimilli (Austin, Texas);  Ravi K. Arimilli (Austin, Texas);  Bernard C. Drerup (Austin, Texas);  Jody B. Joyner (Austin, Texas);  Jerry D. Lewis (Round Rock, Texas)
ABSTRACT A mechanism for performing dynamic request routing based on broadcast source request information is provided. Each processor chip in the system may use a synchronized heartbeat signal it generates to provide source request information to each of the other processor chips in the system. The source request information identifies the number of active source requests sent by the processor chip that originated the heartbeat signal. The source request information from each of the processor chips in the system may be used by the processor chips in determining optimal routing paths for data from a source processor chip to a destination processor chip. As a result, the congestion of data for processing at each of the processor chips along each possible routing path may be taken into account when selecting to which processor chip to forward data.
FILED Friday, February 01, 2008
APPL NO 12/024553
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/235
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779298 Challenger et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James R. Challenger (Garrison, New York);  Louis R. Degenaro (White Plains, New York);  James R. Giles (Yorktown Heights, New York);  Gabriela Jacques Da Silva (Champaign, Illinois)
ABSTRACT A method is provided for the recovery of an instance of a job manager running on one of a plurality of nodes used to execute the processing elements associated with jobs that are executed within a cooperative data stream processing system. The states of the processing elements are checkpointed to a persistence mechanism in communication with the job manager. From the checkpointed processing element states, the state of each distributed job is determined and checkpointed. Processing element states are also checkpointed locally to the nodes one which the processing elements are running. Following a failure of the job manager, the job manager is reinstantiated on one of the nodes. The recovery instance of the job manger obtains state data for processing elements and jobs from the persistence mechanism and constructs an initial state for jobs and processing elements. These initial states are reconciled against the current states of the processing elements and adjustments are made accordingly. Once the job and processing element states are reconciled, the system is returned to normal operation.
FILED Monday, June 11, 2007
APPL NO 11/761152
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/15
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779359 Francis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Gregory S. Francis (West Lafayette, Indiana);  Clarence E. Rash (Fort Rucker, Alabama);  Matthew J. Reardon (Birmingham, Alabama)
ABSTRACT A method that includes but is not limited to accepting user input specifying a geometrical arrangement of two or more buttons on one or more displayed pages; accepting user input labeling at least two of the two or more buttons on the one or more displayed pages; accepting user input defining at least one interaction between the labeled at least two buttons; accepting user input specifying at least one constraint cost for the defined at least one interaction; and assigning the labels of the at least two buttons among the two or more buttons on one or more displayed pages such that the at least one constraint cost is substantially optimized.
FILED Friday, July 20, 2001
APPL NO 09/910669
ART UNIT 2173 — Graphical User Interface and Document Processing
CURRENT CPC
Data processing: Presentation processing of document, operator interface processing, and screen saver display processing
715/762
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07774920 Deng et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Tao Deng (Niskayuna, New York);  Francisco Arias (Mason, Ohio);  Rustem F. Ismagilov (Chicago, Illinois);  Paul J. A. Kenis (Champaign, Illinois);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A method of forming microstructures. An article including a metal atom precursor is disproportionally exposed to electromagnetic radiation in an amount and intensity sufficient to convert some of the precursor to elemental metal. Additional conductive material may then be deposited onto the elemental metal to produce a microstructure.
FILED Wednesday, April 25, 2007
APPL NO 11/789622
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/527.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07774929 Jacobs
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Heiko O. Jacobs (Minneapolis, Minnesota)
ABSTRACT A method of self-assembly of components on a surface of a substrate includes obtaining a first component and a second component. The first component type is assembled onto the substrate by programming the surface. The second component type is assembled by reprogramming the surface. A third component, next to the first and second components, is assembled following the step of assembling the first and second components. The first, second, and third components are all different types of components. docking sites on the substrate can be used that contain alignment pedestals. One component delivery system employ a liquid-liquid interface to deliver and concentrate components with correct pre-orientation.
FILED Wednesday, March 14, 2007
APPL NO 11/686137
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/825
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07774931 Tai et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  University of Southern California (Los Angeles, California)
INVENTOR(S) Yu-Chong Tai (Pasadena, California);  Damien C. Rodger (South Pasadena, California);  Wen Li (East Lansing, California);  Mark Humayun (Glendale, California);  James D. Weiland (Valencia, California);  Hossein Ameri (Galveston, Texas);  Armand R. Tanguay, Jr. (Yorba Linda, California)
ABSTRACT Intraocular retinal prosthesis devices and methods for fabricating the same. A prosthesis device includes a cable region that connects an electrode array region with a power and data management region. The electrode array region includes one or more arrays of exposed electrodes, and the power and data management region includes various power and control elements. The power and data management elements, in one aspect, include an RF coil or coils and circuit arrangements and/or chips configured to provide drive signals to the electrodes via a cable and receive power and signals from the RF coil or coils. Each region includes elements fabricated on or in a single polymer layer during the same fabrication process.
FILED Friday, April 28, 2006
APPL NO 11/414139
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/832
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07774951 Hartmann et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Biology (IOB)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Mitra J. Hartmann (Evanston, Illinois);  Joseph H. Solomon (River Forest, Illinois)
ABSTRACT A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip.
FILED Wednesday, October 03, 2007
APPL NO 11/906751
ART UNIT 2841 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Geometrical instruments
033/552
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775087 Espinosa et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil and Mechanical Systems (CMS)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Horacio D. Espinosa (Winnetka, Illinois);  Nicolaie A. Moldovan (Glenview, Illinois)
ABSTRACT A method of forming a microchannel as well as a thin film structure including same is made by forming a first thin film on a side of a substrate, forming a fugitive second thin film on the first thin film such that the second thin film defines a precursor of the elongated microchannel and a plurality of extensions connected to and extending transversely relative to the precursor along a length thereof A third thin film is formed on the first thin film and the fugitive second thin film such that the second thin film resides between the first thin film and the third thin film. A respective access site is formed in a region of the third thin film residing on a respective extension and penetrating to the fugitive second thin film. The fugitive second thin film forming the precursor is selectively removed from between the first thin film and the third thin film using an etching medium introduced through the access sites, thereby forming the microchannel between the first thin film and the third thin film. The method preferably further includes forming a sealing layer on the third thin film in a manner to close off open access sites remaining after selective removal of the second thin film.
FILED Tuesday, September 05, 2006
APPL NO 11/516039
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/105
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776130 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Can Xue (Evanston, Illinois)
ABSTRACT Silver nanoprisms having a unimodal size distribution are disclosed. The size of the nanoprisms can be controlled by adjusting the pH during irradiation of silver nanocrystals.
FILED Monday, June 18, 2007
APPL NO 11/820087
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/345
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776235 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Milko E. van der Boom (Evanston, Illinois)
ABSTRACT The preparation of robust, thin film materials with large second-order optical nonlinearities through the covalent self-assembly of chromophoric compositions and innovative use of silyl chemistry.
FILED Tuesday, January 13, 2009
APPL NO 12/352792
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/582
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776545 Khosla et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Chaitan Khosla (Palo Alto, California);  Lu Shan (Houston, Texas)
ABSTRACT Detection of toxic gluten oligopeptides refractory to digestion and antibodies and T cells responsive thereto can be used to diagnose Celiac Sprue.
FILED Thursday, November 20, 2003
APPL NO 10/531547
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776565 Betenbaugh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The John Hopkins University (Baltimore, Maryland);  Human Genome Sciences, Inc. (Rockville, Maryland)
INVENTOR(S) Michael J. Betenbaugh (Baltimore, Maryland);  Shawn Lawrence (Dobbs Ferry, New York);  Yuan C. Lee (Timonium, Maryland);  Timothy A. Coleman (Gaithersburg, Maryland)
ABSTRACT Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins.
FILED Friday, February 27, 2009
APPL NO 12/394479
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/84
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776600 Kumta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Prashant N. Kumta (Pittsburgh, Pennsylvania);  Charles Sfeir (Pittsburgh, Pennsylvania);  Jeffrey Owen Hollinger (Pittsburgh, Pennsylvania);  Daiwon Chol (Pittsburgh, Pennsylvania);  Lee Weiss (Pittsburgh, Pennsylvania);  Phil Campbell (Cranberry Township, Pennsylvania)
ABSTRACT Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
FILED Wednesday, June 13, 2007
APPL NO 11/811992
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776642 Eriksson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Mark A. Eriksson (Madison, Wisconsin);  Max G. Lagally (Madison, Wisconsin);  Arnold Melvin Kiefer (Madison, Wisconsin)
ABSTRACT A quantum-well photoelectric device, such as a quantum cascade laser, is constructed of monocrystalline nanoscale membranes physically removed from a substrate and mechanically assembled into a stack.
FILED Thursday, May 15, 2008
APPL NO 12/120933
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/74
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776815 Vanderby et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Ray Vanderby (Madison, Wisconsin);  Kelley Dwyer Grorud (Madison, Wisconsin)
ABSTRACT Disclosed are a method and a corresponding pharmaceutical composition for treating damaged ligaments. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of ligaments damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).
FILED Wednesday, February 23, 2005
APPL NO 11/063627
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776817 Ford
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Morehouse School of Medicine (Atlanta, Georgia)
INVENTOR(S) Byron Ford (Atlanta, Georgia)
ABSTRACT Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke, inflammation or organophosphate neurotoxins. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain.
FILED Friday, September 01, 2006
APPL NO 11/514352
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776927 Chu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Liang-Yin Chu (Chengdu, China PRC);  Ho Cheung Shum (Hong Kong, China PRC);  Alberto Fernandez-Nieves (Atlanta, Georgia);  Andrew S. Utada (Cambridge, Massachusetts);  Enric Santanach Carreras (Cambridge, Massachusetts);  David A. Weitz (Bolton, Massachusetts)
ABSTRACT The present invention generally relates to emulsions such as multiple emulsions, and to methods and apparatuses for making emulsions, and techniques for using the same. A multiple emulsion generally describes larger droplets that contain one or more smaller droplets therein which, in some cases, can contain even smaller droplets therein, etc. Emulsions, including multiple emulsions can be formed in certain embodiments with generally precise repeatability, and can be tailored to include any number of inner droplets, in any desired nesting arrangement, within a single outer droplet. In addition, in some aspects of the invention, one or more droplets may be controllably released from a surrounding droplet.
FILED Friday, March 28, 2008
APPL NO 12/058628
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Colloid systems and wetting agents; subcombinations thereof; processes of
516/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776971 Percec
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Trustees Of The University Of Pennslyvania (Philadelphia, Pennsylvania)
INVENTOR(S) Virgil Percec (Philadelphia, Pennsylvania)
ABSTRACT The inventive subject matter relates to novel synthetic processes which use a multifunctional compound (the “TERMINI compound”) having a masked or protected functional group, wherein the TERMINI compound is capable of quantitatively and irreversibly interrupting a living polymerization or a chain organic reaction. After deprotection or demasking of the functional group of the TERMINI compound, the same living polymerization or organic reaction resumes with 100% efficiency, or a different living polymerization or organic reaction resumes with 100% chemoselectivity, respectively. Once incorporated into a growing molecule, the TERMINI compound generates a branching point upon resumption of the polymerization or reaction.
FILED Thursday, May 06, 2004
APPL NO 10/555599
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
525/342
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777290 Lagally et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Max G. Lagally (Madison, Wisconsin);  Zhenqiang Ma (Middleton, Wisconsin)
ABSTRACT The present invention provides high-speed, high-efficiency PIN diodes for use in photodetector and CMOS imagers. The PIN diodes include a layer of intrinsic semiconducting material, such as intrinsic Ge or intrinsic GeSi, disposed between two tunneling barrier layers of silicon oxide. The two tunneling barrier layers are themselves disposed between a layer of n-type silicon and a layer of p-type silicon.
FILED Tuesday, June 13, 2006
APPL NO 11/452135
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/458
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777392 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Shih-Chi Chen (Boston, Massachusetts);  Martin L. Culpepper (Danvers, Massachusetts)
ABSTRACT A thermomechanical actuation system and method includes an elongated thermomechanical actuator (TMA), which is contoured so that electrical resistance at a mid-portion of the TMA is less than at end portions thereof. A pulse generator is electrically coupled to the TMA, and is configured to supply excitation pulses to the TMA. The excitation pulses are transient, so that each pulse is terminated prior to reaching a steady state amplitude, while having sufficient energy to heat the TMA to its predetermined operational temperature range.
FILED Thursday, November 08, 2007
APPL NO 11/937224
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/306
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777487 Ying et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Lei Ying (Kenosha, Wisconsin);  Jinhua Sheng (Chicago, Illinois)
ABSTRACT A method of parallel magnetic resonance imaging (pMRI) comprising acquiring pMRI signals simultaneously through a plurality of receiving coils, wherein each coil has a localized sensitivity with respect to an imaged volume; jointly estimating values for the imaged volume and for a sensitivity function for at least one of the plurality of receiving coils; and transmitting the reconstructed image to a device.
FILED Friday, February 15, 2008
APPL NO 12/032155
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777505 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Henry S. White (Salt Lake City, Utah);  Ryan J. White (Salt Lake City, Utah);  Eric N. Ervin (Salt Lake City, Utah)
ABSTRACT A nanopore device includes a membrane having a nanopore extending there through forming a channel from a first side of the membrane to a second side of the membrane. The surface of the channel and first side of the membrane are modified with a hydrophobic coating. A first lipid monolayer is deposited on the first side of the membrane, and a second lipid monolayer is deposited on the second side of the membrane, wherein the hydrophobic coating causes spontaneous generation of a lipid bilayer across the nanopore orifice. Sensing entities, such as a protein ion channel, can be inserted and removed from the bilayer by adjusting transmembrane pressure, and adapter molecules can be electrostatically trapped in the ion channel by applying high transmembrane voltages, while resistance or current flow through the sensing entity can be measured electrically.
FILED Wednesday, May 02, 2007
APPL NO 11/743472
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/693
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778165 Madhyastha et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Harsha V. Madhyastha (Seattle, Washington);  Thomas Anderson (Seattle, Washington);  Arvind Krishnamurthy (Seattle, Washington);  Arun Venkataramani (Northampton, Massachusetts)
ABSTRACT Performance metrics between any two arbitrary end-hosts are predicted based upon previous measurements on the Internet between a plurality of geographically dispersed vantage points and clusters of end-hosts. Each cluster comprises end-hosts that are related based upon their IP address prefixes. In response to a central agent that stores the measured data for each of a plurality of predicted paths on the Internet, the vantage points use traceroute software to measure and periodically update performance metrics such as latency, bottleneck capacity, bandwidth, and packet loss rate for links comprising the predicted paths between the vantage points and one (or more) destination points associated with each cluster, and gather such data using distributed application systems. A user or client application can subsequently request predicted performance metrics for communication between specific end-hosts, based upon the previous measurement data.
FILED Thursday, November 08, 2007
APPL NO 11/937223
ART UNIT 2473 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/229
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778301 El-Sayed et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Mostafa A. El-Sayed (Atlanta, Georgia);  Wei Qian (Marietta, Georgia);  Qusai Darugar (Houston, Texas)
ABSTRACT Disclosed is a lasing complex comprising a room temperature solution containing cadmium sulfide (CdS) quantum dots. Optical gain has been observed in CdS nanocrystal quantum dots in strong confinement regime in toluene solution at room temperature using femtosecond transient absorption techniques. The optical gain lifetime is measured to be 20 picoseconds under pump fluence of 0.77 mJ/cm2. The relative lower gain threshold compared to that of CdSe quantum dots is attributed to the long lifetime of fluorescence and biexcitons and the relatively sharp photoluminescence linewidth. The CdS nanocrystals are excellent gain media for semiconductor quantum dot based blue lasers.
FILED Wednesday, June 25, 2008
APPL NO 12/215158
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/51
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778815 Pasricha et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Sudeep Pasricha (Irvine, California);  Nikil Dutt (Irvine, California);  Mohamed Ben-Romdhane (Irvine, California)
ABSTRACT A computer system simulation method starts with algorithmically implementing a specification model independently of hardware architecture. High level functional blocks representing hardware components are connected together using a bus architecture-independent generic channel. The bus architecture-independent generic channel is annotated with timing and protocol details to define an interface between the bus architecture-independent generic channel and functional blocks representing hardware components. The interface is refined to obtain a CCATB for communication space. The read( ) and write( ) interface calls are decomposed into several method calls which correspond to bus pins to obtain observable cycle accuracy for system debugging and validation and to obtain a cycle accurate model. The method calls are replaced by signals, and the functional blocks representing hardware components are further refined to obtain pin/cycle-accurate models which can be manually or automatically mapped to RTL, or be used to co-simulate with existing RTL components.
FILED Thursday, May 26, 2005
APPL NO 11/139370
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/22
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07778995 Qamhiyah et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Abir Ziyad Qamhiyah (Ames, Iowa);  Donald Flugrad (Ames, Iowa)
ABSTRACT One implementation provides a method to provide information associated with a previously designed component having a geometry that is similar to a geometry of a source component. In this implementation, the method includes obtaining a first set of coefficients for a non-invertible representation of the geometry of the source component, and comparing the first set of coefficients to a second set of coefficients for a non-invertible representation of the geometry of the previously designed component. If the first set of coefficients matches the second set of coefficients according to a threshold of similarity, the method further includes providing a search result associated with the previously designed component.
FILED Thursday, April 19, 2007
APPL NO 11/737520
ART UNIT 2166 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/706
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779230 Balakrishnan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Saisanthosh Balakrishnan (Madison, Wisconsin);  Gurindar Singh Sohi (Madison, Wisconsin)
ABSTRACT Distant parallelization of sequential programs is obtained by making parallelization decisions at the boundaries between program methods (e.g., functions and sub-routines). Experimentation suggests that such a partitioning allows for large-scale parallelization without data flow conflicts.
FILED Wednesday, October 18, 2006
APPL NO 11/550687
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/31
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779326 Stankovic et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Vladimir M. Stankovic (Bryan, Texas);  Angelos D. Liveris (Stafford, Texas);  Zixiang Xiong (Spring, Texas);  Costas N. Georghiades (College Station, Texas)
ABSTRACT System and method for designing Slepian-Wolf codes by channel code partitioning. A generator matrix is partitioned to generate a plurality of sub-matrices corresponding respectively to a plurality of correlated data sources. The partitioning is performed in accordance with a rate allocation among the plurality of correlated data sources. A corresponding plurality of parity matrices are generated based respectively on the sub-matrices, where each parity matrix is useable to encode data from a respective one of the correlated data sources.
FILED Tuesday, March 01, 2005
APPL NO 11/069935
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/752
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07775086 Jesse et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Stephen Jesse (Knoxville, Tennessee);  Sergei V. Kalinin (Knoxville, Tennessee)
ABSTRACT Methods and apparatus are described for scanning probe microscopy. A method includes generating a band excitation (BE) signal having finite and predefined amplitude and phase spectrum in at least a first predefined frequency band; exciting a probe using the band excitation signal; obtaining data by measuring a response of the probe in at least a second predefined frequency band; and extracting at least one relevant dynamic parameter of the response of the probe in a predefined range including analyzing the obtained data. The BE signal can be synthesized prior to imaging (static band excitation), or adjusted at each pixel or spectroscopy step to accommodate changes in sample properties (adaptive band excitation). An apparatus includes a band excitation signal generator; a probe coupled to the band excitation signal generator; a detector coupled to the probe; and a relevant dynamic parameter extractor component coupled to the detector, the relevant dynamic parameter extractor including a processor that performs a mathematical transform selected from the group consisting of an integral transform and a discrete transform.
FILED Friday, September 01, 2006
APPL NO 11/515348
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/105
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775305 Fischer
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Gary J. Fischer (Albuquerque, New Mexico)
ABSTRACT The present invention provides robotic vehicles having wheeled and hopping mobilities that are capable of traversing (e.g. by hopping over) obstacles that are large in size relative to the robot and, are capable of operation in unpredictable terrain over long range. The present invention further provides combustion powered linear actuators, which can include latching mechanisms to facilitate pressurized fueling of the actuators, as can be used to provide wheeled vehicles with a hopping mobility.
FILED Thursday, August 31, 2006
APPL NO 11/513717
ART UNIT 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Motor vehicles
180/8.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775368 Schwartz et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) David Charles Schwartz (Madison, Wisconsin);  Eileen T. Dimalanta (Madison, Wisconsin);  Juan J. de Pablo (Madison, Wisconsin)
ABSTRACT Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten, align, separate, and/or sort the polymeric molecules. The polymeric molecules may be analyzed and/or manipulated in the carrier liquid or attached to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge.
FILED Friday, October 17, 2003
APPL NO 10/688416
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Classifying, separating, and assorting solids
29/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775961 Meikrantz
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David H. Meikrantz (Idaho Falls, Idaho)
ABSTRACT Centrifuge samples may be exposed to microwave energy to heat the samples during centrifugation and to promote separation of the different components or constituents of the samples using a centrifuge device configured for generating microwave energy and directing the microwave energy at a sample located in the centrifuge.
FILED Monday, February 06, 2006
APPL NO 11/349484
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Imperforate bowl: Centrifugal separators
494/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776357 Davalos et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Livermore, California)
INVENTOR(S) Rafael V. Davalos (Oakland, California);  Christopher R. B. Ellis (Oakland, California)
ABSTRACT Disclosed is an apparatus and method for inserting one or several chemical or biological species into phospholipid containers that are controlled within a microfluidic network, wherein individual containers are tracked and manipulated by electric fields and wherein the contained species may be chemically processed.
FILED Tuesday, February 05, 2008
APPL NO 12/012839
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776405 Bailey et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) George Mason Intellectual Properties, Inc. (Fairfax, Virginia)
INVENTOR(S) Charles L. Bailey (Cross Junction, Virginia);  Victor Morozov (Manassas, Virginia);  Nikolai N. Vsevolodov (Kensington, Maryland)
ABSTRACT The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.
FILED Friday, November 17, 2006
APPL NO 11/561138
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/483
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776479 Sopchak et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) David A. Sopchak (Livermore, California);  Jeffrey D. Morse (Martinez, California);  Ravindra S. Upadhye (Pleasanton, California);  Jack Kotovsky (Oakland, California);  Robert T. Graff (Modesto, California)
ABSTRACT A phosphoric acid fuel cell system comprising a porous electrolyte support, a phosphoric acid electrolyte in the porous electrolyte support, a cathode electrode contacting the phosphoric acid electrolyte, and an anode electrode contacting the phosphoric acid electrolyte.
FILED Thursday, April 28, 2005
APPL NO 11/119525
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776532 Gibson et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Synthetic Genomics, Inc. (San Diego, California)
INVENTOR(S) Daniel Glenn Gibson (Crofton, Maryland);  Hamilton O. Smith (Reisterstown, Maryland)
ABSTRACT The present invention relates, e.g., to an in vitro method, using isolated protein reagents, for joining two double-stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity, comprising (a) chewing back the DNA molecules with an enzyme having an exonuclease activity, to yield single-stranded overhanging portions of each DNA molecule which contain a sufficient length of the region of sequence identity to hybridize specifically to each other; (b) specifically annealing the single-stranded overhangs; and (c) repairing single-stranded gaps in the annealed DNA molecules and sealing the nicks thus formed (ligating the nicked DNA molecules). The region of sequence identity generally comprises at least 20 non-palindromic nucleotides (nt), e.g., at least about 40 non-palindromic nt. In some embodiments of the invention, about 5% PEG is present during all steps of the reaction, and/or the repair reaction is achieved with Taq DNA polymerase and a compatible ligase, such as Taq DNA ligase. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. It can be used, e.g., to join synthetically produced sub-fragments of a gene or genome of interest.
FILED Friday, August 11, 2006
APPL NO 11/502624
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776642 Eriksson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Mark A. Eriksson (Madison, Wisconsin);  Max G. Lagally (Madison, Wisconsin);  Arnold Melvin Kiefer (Madison, Wisconsin)
ABSTRACT A quantum-well photoelectric device, such as a quantum cascade laser, is constructed of monocrystalline nanoscale membranes physically removed from a substrate and mechanically assembled into a stack.
FILED Thursday, May 15, 2008
APPL NO 12/120933
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/74
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776780 Granite et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) Evan J. Granite (Wexford, Pennsylvania);  Henry W. Pennline (Bethel Park, Pennsylvania)
ABSTRACT Two new classes of catalysts for the removal of heavy metal contaminants, especially mercury (Hg) from effluent gases. Both of these classes of catalysts are excellent absorbers of HCl and Cl2 present in effluent gases. This adsorption of oxidizing agents aids in the oxidation of heavy metal contaminants. The catalysts remove mercury by oxidizing the Hg into mercury (II) moieties. For one class of catalysts, the active component is selected from the group consisting of iridium (Ir) and iridum-platinum (Ir/Pt) alloys. The Ir and Ir/Pt alloy catalysts are especially corrosion resistant. For the other class of catalyst, the active component is partially combusted coal or “Thief” carbon impregnated with Cl2. Untreated Thief carbon catalyst can be self-activating in the presence of effluent gas streams. The Thief carbon catalyst is disposable by means of capture from the effluent gas stream in a particulate collection device (PCD).
FILED Thursday, July 14, 2005
APPL NO 11/183221
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/181
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776782 Werpy et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Todd Werpy (West Richland, Washington);  John G. Frye, Jr. (Richland, Washington);  Yong Wang (Richland, Washington);  Alan H. Zacher (Kennewick, Washington)
ABSTRACT A textured catalyst having a hydrothermally-stable support, a metal oxide and a catalyst component is described. Methods of conducting aqueous phase reactions that are catalyzed by a textured catalyst are also described. The invention also provides methods of making textured catalysts and methods of making chemical products using a textured catalyst.
FILED Monday, January 08, 2007
APPL NO 11/651360
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/185
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776999 Mayer-Cumblidge et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) M. Uljana Mayer-Cumblidge (Richland, Washington);  Haishi Cao (Richland, Washington)
ABSTRACT A molecular probe comprises two arsenic atoms and at least one cyanine based moiety. A method of producing a molecular probe includes providing a molecule having a first formula, treating the molecule with HgOAc, and subsequently transmetallizing with AsCl3. The As is liganded to ethanedithiol to produce a probe having a second formula. A method of labeling a peptide includes providing a peptide comprising a tag sequence and contacting the peptide with a biarsenical molecular probe. A complex is formed comprising the tag sequence and the molecular probe. A method of studying a peptide includes providing a mixture containing a peptide comprising a peptide tag sequence, adding a biarsenical probe to the mixture, and monitoring the fluorescence of the mixture.
FILED Thursday, April 12, 2007
APPL NO 11/787078
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777016 Okumoto et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Non-Profit Organization (NPO)
Human Frontier Science Program (HFSP)
APPLICANT(S)
ASSIGNEE(S) Carnegie Institution of Washington (Washington, District of Columbia)
INVENTOR(S) Sakiko Okumoto (Washington, District of Columbia);  Loren L. Looger (Washington, District of Columbia);  Wolf B. Frommer (Washington, District of Columbia)
ABSTRACT Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture.
FILED Friday, October 14, 2005
APPL NO 11/665343
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777182 Dahl et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David A. Dahl (Idaho Falls, Idaho);  Jill R. Scott (Idaho Falls, Idaho);  Timothy R. McJunkin (Idaho Falls, Idaho)
ABSTRACT An ion cyclotron spectrometer may include a vacuum chamber that extends at least along a z-axis and means for producing a magnetic field within the vacuum chamber so that a magnetic field vector is generally parallel to the z-axis. The ion cyclotron spectrometer may also include means for producing a trapping electric field within the vacuum chamber that includes at least a first section that induces a first magnetron effect that increases a cyclotron frequency of an ion and at least a second section that induces a second magnetron effect that decreases the cyclotron frequency of an ion. The cyclotron frequency changes induced by the first and second magnetron effects substantially cancel one another so that an ion traversing the at least first and second sections will experience no net change in cyclotron frequency.
FILED Thursday, August 02, 2007
APPL NO 11/833079
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/291
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777185 de Jonge
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Niels de Jonge (Oak Ridge, Tennessee)
ABSTRACT A confocal scanning transmission electron microscope which includes an electron illumination device providing an incident electron beam propagating in a direction defining a propagation axis, and a precision specimen scanning stage positioned along the propagation axis and movable in at least one direction transverse to the propagation axis. The precision specimen scanning stage is configured for positioning a specimen relative to the incident electron beam. A projector lens receives a transmitted electron beam transmitted through at least part of the specimen and focuses this transmitted beam onto an image plane, where the transmitted beam results from the specimen being illuminated by the incident electron beam. A detection system is placed approximately in the image plane.
FILED Tuesday, September 25, 2007
APPL NO 11/860760
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/311
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777233 Kahen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Eastman Kodak Company (Rochester, New York)
INVENTOR(S) Keith B. Kahen (Rochester, New York);  Xiaofan Ren (Rochester, New York)
ABSTRACT An optoelectronic device including two spaced apart electrodes; and at least one layer containing ternary core/shell nanocrystals disposed between the spaced electrodes and having ternary semiconductor cores containing a gradient in alloy composition and wherein the ternary core/shell nanocrystals exhibit single molecule non-blinking behavior characterized by on times greater than one minute or radiative lifetimes less than 10 ns.
FILED Tuesday, October 30, 2007
APPL NO 11/928292
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/79
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777303 Alivisatos et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of California (Oakland, California)
INVENTOR(S) A. Paul Alivisatos (Oakland, California);  Janke J. Dittmer (Munich, Germany);  Wendy U. Huynh (Munich, Germany);  Delia Milliron (Berkeley, California)
ABSTRACT The invention described herein provides for thin films and methods of making comprising inorganic semiconductor-nanocrystals dispersed in semiconducting-polymers in high loading amounts. The invention also describes photovoltaic devices incorporating the thin films.
FILED Tuesday, March 18, 2003
APPL NO 10/392668
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Active solid-state devices
257/615
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777516 Zhou et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Eaton Corporation (Cleveland, Ohio)
INVENTOR(S) Wei Zhou (Los Angeles, California);  Bin Lu (Kenosha, Wisconsin);  Thomas G. Habetler (Snellville, Georgia);  Ronald G. Harley (Lawrenceville, Georgia);  Peter J. Theisen (West Bend, Wisconsin)
ABSTRACT A system and method for detecting incipient mechanical motor faults by way of current noise cancellation is disclosed. The system includes a controller configured to detect indicia of incipient mechanical motor faults. The controller further includes a processor programmed to receive a baseline set of current data from an operating motor and define a noise component in the baseline set of current data. The processor is also programmed to repeatedly receive real-time operating current data from the operating motor and remove the noise component from the operating current data in real-time to isolate any fault components present in the operating current data. The processor is then programmed to generate a fault index for the operating current data based on any isolated fault components.
FILED Tuesday, June 03, 2008
APPL NO 12/132056
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Electricity: Measuring and testing
324/772
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777665 Doerry et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Armin W. Doerry (Albuquerque, New Mexico);  Freddie E. Heard (Albuquerque, New Mexico);  J. Thomas Cordaro (Albuquerque, New Mexico)
ABSTRACT Motion measurement errors that extend beyond the range resolution of a synthetic aperture radar (SAR) can be corrected by effectively decreasing the range resolution of the SAR in order to permit measurement of the error. Range profiles can be compared across the slow-time dimension of the input data in order to estimate the error. Once the error has been determined, appropriate frequency and phase correction can be applied to the uncompressed input data, after which range and azimuth compression can be performed to produce a desired SAR image.
FILED Wednesday, May 14, 2008
APPL NO 12/120270
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/25.E00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779173 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Michael A. Blocksome (Rochester, Minnesota);  Jeffrey J. Parker (Rochester, Minnesota)
ABSTRACT Methods, apparatus, and products are disclosed for DMA transfer completion notification that include: inserting, by an origin DMA engine on an origin compute node in an injection FIFO buffer, a data descriptor for an application message to be transferred to a target compute node on behalf of an application on the origin compute node; inserting, by the origin DMA engine, a completion notification descriptor in the injection FIFO buffer after the data descriptor for the message, the completion notification descriptor specifying an address of a completion notification field in application storage for the application; transferring, by the origin DMA engine to the target compute node, the message in dependence upon the data descriptor; and notifying, by the origin DMA engine, the application that the transfer of the message is complete, including performing a local direct put operation to store predesignated notification data at the address of the completion notification field.
FILED Tuesday, May 29, 2007
APPL NO 11/754719
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital data processing systems: Input/output
710/22
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE41504 Maziasz et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Caterpillar Inc. (Peoria, Illinois)
INVENTOR(S) Philip J. Maziasz (Oak Ridge, Tennessee);  Tim McGreevy (Washington, Illinois);  Michael James Pollard (Peoria, Illinois);  Chad W. Siebenaler (Dunlap, Illinois);  Robert W. Swindeman (Oak Ridge, Tennessee)
ABSTRACT A CF8C type stainless steel alloy and articles formed therefrom containing about 18.0 weight percent to about 22.0 weight percent chromium and 11.0 weight percent to about 14.0 weight percent nickel; from about 0.05 weight percent to about 0.15 weight percent carbon; from about 2.0 weight percent to about 10.0 weight percent manganese; and from about 0.3 weight percent to about 1.5 weight percent niobium. The present alloys further include less than 0.15 weight percent sulfur which provides high temperature strength both in the matrix and at the grain boundaries without reducing ductility due to cracking along boundaries with continuous or nearly-continuous carbides. The disclosed alloys also have increased nitrogen solubility thereby enhancing strength at all temperatures because nitride precipitates or nitrogen porosity during casting are not observed. The solubility of nitrogen is dramatically enhanced by the presence of manganese, which also retains or improves the solubility of carbon thereby providing additional solid solution strengthening due to the presence of manganese and nitrogen, and combined carbon.
FILED Monday, August 25, 2008
APPL NO 12/230179
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal treatment
148/327
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07776337 Stern et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Norman J Stern (Athens, Georgia);  Edward A Svetoch (Serpukhov District, Russian Federation);  Boris V Eruslanov (Serpukhov District, Russian Federation);  Vladimir V Perelygin (Serpukhov District, Russian Federation);  Vladimir P Levchuk (Serpukhov District, Russian Federation);  Larisa I Volodina (Serpukhov District, Russian Federation);  Yuri N. Kovalev (Serpukhov District, Russian Federation);  Tamara Y. Kudryavtseva (Serpukhov District, Russian Federation);  Victor D. Pokhilenko (Serpukhov District, Russian Federation);  Valery N. Borzenkov (Serpukhov District, Russian Federation);  Olga E. Svetoch (Serpukhov District, Russian Federation);  Eugeni V. Mitsevich (Serpukhov Distict, Russian Federation);  Irina P. Mitsevich (Serpukhov District, Russian Federation)
ABSTRACT Novel bacteriocins and/or the novel lactic acid-producing strains are used for at least reducing the levels of colonization by at least one target bacteria in animals, especially poultry.
FILED Friday, August 15, 2008
APPL NO 12/192778
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/190.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP21217 Henny et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S)
ASSIGNEE(S) Florida Foundation Seed Producers, Inc. (Marianna, Florida)
INVENTOR(S) Richard Henny (Tavares, Florida);  Jianjun Chen (Apopka, Florida)
ABSTRACT A new Epipremnum plant particularly distinguished by having small variegated leaves with three different colors, irregularly undulated rather than smooth leaf surfaces, and compact and dense growth habit, is disclosed.
FILED Tuesday, December 09, 2008
APPL NO 12/316132
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/373
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07774951 Hartmann et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Biology (IOB)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Mitra J. Hartmann (Evanston, Illinois);  Joseph H. Solomon (River Forest, Illinois)
ABSTRACT A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip.
FILED Wednesday, October 03, 2007
APPL NO 11/906751
ART UNIT 2841 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Geometrical instruments
033/552
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07775261 Valenzuela
FUNDED BY
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) Mikros Manufacturing, Inc. (Claremont, New Hampshire)
INVENTOR(S) Javier A. Valenzuela (Grantham, New Hampshire)
ABSTRACT A heat transfer device is disclosed for transferring heat to or from a fluid that is undergoing a phase change. The heat transfer device includes a liquid-vapor manifold in fluid communication with a capillary structure thermally connected to a heat transfer interface, all of which are disposed in a housing to contain the vapor. The liquid-vapor manifold transports liquid in a first direction and conducts vapor in a second, opposite direction. The manifold provides a distributed supply of fluid (vapor or liquid) over the surface of the capillary structure. In one embodiment, the manifold has a fractal structure including one or more layers, each layer having one or more conduits for transporting liquid and one or more openings for conducting vapor. Adjacent layers have an increasing number of openings with decreasing area, and an increasing number of conduits with decreasing cross-sectional area, moving in a direction toward the capillary structure.
FILED Tuesday, March 08, 2005
APPL NO 11/075467
ART UNIT 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Heat exchange
165/104.260
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07778183 Fan et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Jinliang Fan (Redmond, Washington);  Nagui Halim (Yorktown Heights, New York);  Zhen Liu (Tarrytown, New York);  Dimitrios Pendarakis (Westport, Connecticut)
ABSTRACT A method is provided for selecting a replication node from eligible nodes in a network. A multidimensional model is constructed that defines a multidimensional space and includes the eligible nodes, with each of the dimensions of the multidimensional model being a system characteristic. A data availability value is determined for each of the eligible nodes, and a cost of deploying is determined for each of at least two availability strategies to the eligible nodes. At least one of the eligible nodes is selected for replication of data that is stored on a source node in the network. The selecting step includes selecting the eligible node whose: data availability value is determined to be highest among the eligible nodes whose cost of deploying does not exceed a specified maximum, or cost of deploying is determined to be lowest among the eligible nodes whose data availability value does not exceed a specified minimum.
FILED Tuesday, February 20, 2007
APPL NO 11/676631
ART UNIT 2471 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/238
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779298 Challenger et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James R. Challenger (Garrison, New York);  Louis R. Degenaro (White Plains, New York);  James R. Giles (Yorktown Heights, New York);  Gabriela Jacques Da Silva (Champaign, Illinois)
ABSTRACT A method is provided for the recovery of an instance of a job manager running on one of a plurality of nodes used to execute the processing elements associated with jobs that are executed within a cooperative data stream processing system. The states of the processing elements are checkpointed to a persistence mechanism in communication with the job manager. From the checkpointed processing element states, the state of each distributed job is determined and checkpointed. Processing element states are also checkpointed locally to the nodes one which the processing elements are running. Following a failure of the job manager, the job manager is reinstantiated on one of the nodes. The recovery instance of the job manger obtains state data for processing elements and jobs from the persistence mechanism and constructs an initial state for jobs and processing elements. These initial states are reconciled against the current states of the processing elements and adjustments are made accordingly. Once the job and processing element states are reconciled, the system is returned to normal operation.
FILED Monday, June 11, 2007
APPL NO 11/761152
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/15
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 07776553 Love et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Non-Profit Organization (NPO)
National Academy of Sciences
APPLICANT(S)
ASSIGNEE(S) Presidents and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) J. Christopher Love (Cambridge, Massachusetts);  Hidde L. Ploegh (Brookline, Massachusetts);  Jehnna Ronan (Chester, New Hampshire)
ABSTRACT Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with each other. In some examples, the assays and methods may be used to determine if a known antigen binds to an unknown monoclonal antibody.
FILED Monday, September 18, 2006
APPL NO 11/523124
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07777016 Okumoto et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Non-Profit Organization (NPO)
Human Frontier Science Program (HFSP)
APPLICANT(S)
ASSIGNEE(S) Carnegie Institution of Washington (Washington, District of Columbia)
INVENTOR(S) Sakiko Okumoto (Washington, District of Columbia);  Loren L. Looger (Washington, District of Columbia);  Wolf B. Frommer (Washington, District of Columbia)
ABSTRACT Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture.
FILED Friday, October 14, 2005
APPL NO 11/665343
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.400
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07775174 Humphreys et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Vehicle Control Technologies, Inc. (Reston, Virginia)
INVENTOR(S) Douglas E. Humphreys (Great Falls, Virginia);  Ryan D. Schulz (Reston, Virginia);  Alexander V. Roup (Sterling, Virginia);  Neill S. Smith (Springfield, Virginia);  Daniel N. Dietz (Alexandria, Virginia)
ABSTRACT An at least partially self-propelled vehicle is configured for being towed by a towing vehicle, by way of a tow line. Operation of the vehicles may be coordinated so that, for a length of the tow line that connects the vehicles, the length of the tow line is curved in a manner that inhibits the tow line from transferring oscillatory motion between the vehicles while the entirety of the length of the tow line may be under tension.
FILED Friday, August 29, 2008
APPL NO 12/231238
ART UNIT 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships
114/244
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776153 Schowalter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Missile Defense Agency (MDA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Crystal IS, Inc. (Green Island, New York)
INVENTOR(S) Leo J. Schowalter (Latham, New York);  Glen A. Slack (Scotia, New York);  J. Carlos Rojo (East Setauket, New York)
ABSTRACT A method and apparatus for producing bulk single crystals of AlN having low dislocation densities of about 10,000 cm−2 or less includes a crystal growth enclosure with Al and N2 source material therein, capable of forming bulk crystals. The apparatus maintains the N2 partial pressure at greater than stoichiometric pressure relative to the Al within the crystal growth enclosure, while maintaining the total vapor pressure in the crystal growth enclosure at super-atmospheric pressure. At least one nucleation site is provided in the crystal growth enclosure, and provision is made for cooling the nucleation site relative to other locations in the crystal growth enclosure. The Al and N2 vapor is then deposited to grow single crystalline low dislocation density AlN at the nucleation site. High efficiency ultraviolet light emitting diodes and ultraviolet laser diodes are fabricated on low defect density AlN substrates, which are cut from the low dislocation density AlN crystals. Bulk crystals of ZnO may also be produced using the method.
FILED Thursday, November 03, 2005
APPL NO 11/265909
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/81
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07778840 Krause et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Robert Krause (Severna Park, Maryland);  Wayne H. Orbke (Germantown, Tennessee);  Harry W. Aldstadt (Woodbridge, Virginia);  Michael Murphy (Collierville, Tennessee);  Audrey K. Conley Williams (Memphis, Tennessee);  Gerald Matthews (Germantown, Tennessee);  Pat Matthews, legal representative (Germnatown, Tennessee);  Michael Selnick (Reston, Virginia)
ABSTRACT This disclosure describes systems and methods for collecting and processing change of address data and providing change of address services to a customer using a computer network. The address data can include a physical address, an electronic address, or both. The systems and methods may also provide additional services to the customer to assist in changing addresses.
FILED Monday, April 23, 2001
APPL NO 09/839241
ART UNIT 3714 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07779481 Chamberlain
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Charles R. Chamberlain (Arlington, Virginia)
ABSTRACT Systems and mehods for electronic postmarking of location data are provided. Electronic postmarking of location data (S.20) includes generating a hash value corresponding to merged data (S.30). Electronic postmarking further includes generating an electronic postmark data structure (S.40) comprising the hash value and a date/time stamp. The electronic postmarking data structure (S.40) may further include a digital signature.
FILED Friday, April 12, 2002
APPL NO 10/474730
ART UNIT 2432 — Cryptography and Security
CURRENT CPC
Information security
726/28
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07776240 Chu et al.
FUNDED BY
Department of Commerce (DOC)
National Textile Center (NTC)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Chih-Chang Chu (Ithaca, New York);  Xian-Zheng Zhang (Wuhan, China PRC);  Da-Qing Wu (Ithaca, New York)
ABSTRACT Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution.
FILED Thursday, December 04, 2003
APPL NO 10/538477
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/4.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07775261 Valenzuela
FUNDED BY
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S)
ASSIGNEE(S) Mikros Manufacturing, Inc. (Claremont, New Hampshire)
INVENTOR(S) Javier A. Valenzuela (Grantham, New Hampshire)
ABSTRACT A heat transfer device is disclosed for transferring heat to or from a fluid that is undergoing a phase change. The heat transfer device includes a liquid-vapor manifold in fluid communication with a capillary structure thermally connected to a heat transfer interface, all of which are disposed in a housing to contain the vapor. The liquid-vapor manifold transports liquid in a first direction and conducts vapor in a second, opposite direction. The manifold provides a distributed supply of fluid (vapor or liquid) over the surface of the capillary structure. In one embodiment, the manifold has a fractal structure including one or more layers, each layer having one or more conduits for transporting liquid and one or more openings for conducting vapor. Adjacent layers have an increasing number of openings with decreasing area, and an increasing number of conduits with decreasing cross-sectional area, moving in a direction toward the capillary structure.
FILED Tuesday, March 08, 2005
APPL NO 11/075467
ART UNIT 3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Heat exchange
165/104.260
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07776326 Milbrandt et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Washington University (Saint Louis, Missouri)
INVENTOR(S) Jeffrey Milbrandt (St. Louis, Missouri);  Toshiyuki Araki (Tokyo, Japan);  Yo Sasaki (Saint Louis, Missouri)
ABSTRACT Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.
FILED Friday, June 03, 2005
APPL NO 11/144358
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/94.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07776327 Kinch et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Michael S. Kinch (Laytonsville, Maryland);  Nicole D. Zantek (Silver Spring, Maryland);  Patrick W. Hein (Columbia, Illinois)
ABSTRACT The present invention is directed to compounds and methods for the treatment of cancer. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase that is overexpressed in metastatic tumor cells. The compounds used in accordance with this invention may be provided in a pharmaceutical composition for treatment of metastatic cancer.
FILED Thursday, December 08, 2005
APPL NO 11/297548
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 

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THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, August 17, 2010.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

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Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

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FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100817.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital