FedInvent™ Patents

Patent Details for Tuesday, August 31, 2010 

This page was updated on Monday, March 27, 2023 at 01:53 AM GMT

Department of Health and Human Services (HHS) 

US 07784697 Johnston et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Richard S Johnston (Sammamish, Washington);  Matthew J Kundrat (Seattle, Washington);  Per G Reinhall (Seattle, Washington)
ABSTRACT The present invention provides methods and systems for scanning an illumination spot over a target area. The present invention removes stored energy from a scanning element to stop the scanning element from vibrating and to substantially return the scanning element to its starting position so as to enable high frame rates.
FILED Thursday, January 03, 2008
APPL NO 11/969141
ART UNIT 2887 — Optics
CURRENT CPC
Registers
235/462.320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785232 Cole et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Neil M. Cole (Dexter, Michigan);  Charles L. Cole (Livonia, Michigan);  Walter N. Cole (Livonia, Michigan)
ABSTRACT A training system and method include providing a frame, a user support portion coupled to the frame and arranged to support a user, and a user engagement portion coupled to the frame and arranged to be engaged by the body part. A force sensor is provided for sensing a user-applied force at the user engagement portion, and a position sensor is operably connected to at least one of the user support portion and the user engagement portion for sensing a relative position therebetween. A motor is coupled to at least one of the user support portion and the user engagement portion for driving a position thereof with respect to the frame over a range of motion at a preprogrammed velocity, and a controller is provided in communication with the motor, the force sensor, and the position sensor. A computer program executable by the controller generates a position-varying target force band for the user over the range of motion, and a display is provided in communication with the controller and the force and position sensors for displaying the user-applied force as a function of position in real time in comparison with the target force band.
FILED Tuesday, November 27, 2007
APPL NO 11/945525
ART UNIT 3764 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Exercise devices
482/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785259 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Yi Zheng (Sartell, Minnesota);  Wei Tan (St. Cloud, Minnesota);  James Fowler Greenleaf (Rochester, Minnesota);  Shigao Chen (Rochester, Minnesota)
ABSTRACT Harmonic motion is produced in a subject using vibro-acoustography. An ultrasonic imaging system repetitively interrogates the subject and the Doppler shift in the reflected echo signals is analyzed to measure the phase and amplitude of harmonic motion produced in the subject at different prescribed frequencies. Shear wave propagation through the subject is determined from this information and mechanical properties related to “stiffness” of the subject are determined. A Kalman filter is employed in the phase and amplitude measurement to extract the harmonic motion information from background noise.
FILED Friday, October 01, 2004
APPL NO 10/956461
ART UNIT 3768 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Surgery
6/438
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785564 Khan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Saeed R. Khan (Owings Mills, Maryland);  Bert Vogelstein (Baltimore, Maryland);  Kenneth W. Kinzler (Bel Air, Maryland);  Hallur Gurulingappa (Baltimore, Maryland);  Phillip Buckhaults (Columbia, South Carolina)
ABSTRACT Aminophosphinic acid derivatives were synthesized as potential inhibitors of renal dipeptidase, an enzyme overexpressed in benign and malignant colon tumors. Several compounds showed potent enzyme-inhibitory activity. These compounds can be used therapeutically and diagnostically for treatment and detection of tumors.
FILED Thursday, July 07, 2005
APPL NO 11/175478
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.650
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785565 Brechbiel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Martin Wade Brechbiel (Annandale, Virginia);  Thomas Clifford (Rockville, Maryland)
ABSTRACT Metal chelators of Formula I and Formula II are disclosed: or a pharmaceutically acceptable salt thereof. Also disclosed are metal chelator-targeting moiety complexes, metal chelator-targeting moiety-metal conjugates, kits, and methods of their preparation and use in diagnosis and/or treatment of diseases and conditions, including, inter alia, cancer and thrombosis.
FILED Tuesday, August 09, 2005
APPL NO 11/659601
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.650
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785597 Norris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Steven J. Norris (Houston, Texas);  Jing-Ren Zhang (Delmar, New York);  John M. Hardham (Gales Ferry, Connecticut);  Jerrilyn K. Howell (Houston, Texas);  Alan G. Barbour (Newport Beach, California);  George M. Weinstock (Houston, Texas)
ABSTRACT The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
FILED Monday, August 07, 2006
APPL NO 11/501166
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/185.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785598 Branch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Andrea D. Branch (New York, New York);  Jose L. Walewski (Eastchester, New York);  Decherd D. Stump (New York, New York)
ABSTRACT Novel hepatitis C virus (HCV) polypeptides are provided which are not encoded by the standard HCV open reading frame. These alternate reading frame polypeptides are useful, inter alia, in vaccine compositions, in diagnosing HCV infection, and as therapeutic targets.
FILED Tuesday, February 20, 2007
APPL NO 11/708175
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/189.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785605 Davido et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) David Davido (Lawrence, Kansas);  Priscilla Schaffer (Tucson, Arizona)
ABSTRACT A mutant virus of herpes simplex virus type 1 (HSV-1) can include a mutant protein involved in replication so as to impair or inhibit replication of HSV-1. The mutant HSV-1 can have a mutation in at least one phosphorylation site of a protein involved in replication in order to inhibit phosphorylation of the site so as to prohibit or impair replication of HSV-1 and/or the clinical severity of HSV-1-mediated diseases. The mutant protein can be a mutant ICP0 that has reduced or inhibited posttranslational phosphorylation. The mutant HSV-1 and/or mutant ICP0 can be used in vaccines or other pharmaceutical preparations to treat, limit and/or prevent HSV-1 infection. The mutant HSV-1 and/or mutant ICP0 can also be used in screening and/or developing anti-HSV-1 agents.
FILED Thursday, July 03, 2008
APPL NO 12/167870
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/231.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785618 Elmaleh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) David R. Elmaleh (Newton, Massachusetts);  Simon C. Robson (Weston, Massachusetts);  Mikhail L. Papisov (Winchester, Massachusetts)
ABSTRACT Biologically active agents covalently linked to a polymer. The polymer is preferably a biodegradable polymer are provided. The biologically active agent is preferably a protein, such as an extracellular soluble protein, e.g., an extracellular enzyme. The enzyme can be an apyrase, e.g., NTPDase. Conjugates of the invention can be used as therapeutics in subjects. For example, a conjugate comprising an apyrase can be used for treating and preventing thrombosis, atherosclerotic plaque complications and vascular disorders.
FILED Friday, August 20, 2004
APPL NO 10/922378
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/426
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785621 Maurer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Childrens Hospital Los Angeles (Los Angeles, California)
INVENTOR(S) Barry J. Maurer (Sylmar, California);  Charles Patrick Reynolds (Sherman Oaks, California);  David W. Yesair (Byfield, Massachusetts);  Robert Travis McKee (Jacksonville, Florida);  Stephen W. Burgess (Chelsea, Alabama);  Walter A. Shaw (Birmingham, Alabama)
ABSTRACT The present invention provides an edible composition for oral delivery of an active agent such as a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of the invention may be administered per se or mixed with a solid or liquid food carrier, for direct oral consumption by a subject or administration through a feeding tube.
FILED Friday, January 30, 2004
APPL NO 10/767352
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/439
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785776 Wittwer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Idaho Technology, Inc. (Salt Lake City, Utah);  University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Carl T. Wittwer (Salt Lake City, Utah);  Cameron Gundry (Cottonwood Heights, Utah);  Richard David Abbott (Draper, Utah);  Derek Allen David (Tooele, Utah)
ABSTRACT Methods for analyzing a target nucleic acid are provided. A fluorescent label attached to a nucleic acid is incorporated into at least one strand of the target nucleic acid and the methods include monitoring change in fluorescence emission resulting from dissociation of the labeled strand of the amplification product from its complementary strand.
FILED Thursday, May 08, 2003
APPL NO 10/431804
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07785785 Pourmand et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Nader Pourmand (San Mateo, California);  Ronald W. Davis (Palo Alto, California);  Miloslav Karhanek (Palo Alto, California)
ABSTRACT Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The target molecule is preferably DNA. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. The initial enzyme attachment to the DNA molecule can be detected prior to polymerization, with electrode capacitance measurement using the same voltage-clamp amplifier. This technique and device may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits.
FILED Thursday, November 10, 2005
APPL NO 11/271678
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785799 Barrett et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Alan Barrett (Galveston, Texas);  David Beasley (Galveston, Texas);  Michael Holbrook (Oklahoma City, Oklahoma)
ABSTRACT The present invention concerns methods and compositions involving flavivirus envelope protein domain III antigens for the detection of virus and detection of antibodies against the virus. Such methods and compositions may be used to detect TBE serocomplex viruses or West Nile virus infection in a subject, patient, animal or biological fluid. The present invention also concerns kits for implementing such methods. In some embodiments, kits contain a recombinant TBE serocomplex virus or West Nile virus envelope protein domain III antigen.
FILED Monday, August 18, 2003
APPL NO 10/524939
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785807 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) Monell Chemical Senses Center (Philadelphia, Pennsylvania)
INVENTOR(S) Liquan Huang (Havertown, Pennsylvania);  Jie Cao (Upper Darby, Pennsylvania);  Hong Wang (Havertown, Pennsylvania);  Joseph G Brand (Wayne, Pennsylvania)
ABSTRACT The invention provides a novel splice-variant of the ClC-4 protein, termed ClC-4A. ClC-4A is expressed in taste bud cells and is involved in sour taste perception. The invention provides ClC-4A polynucleotides and ClC-4A polypeptides, vectors, host cells and ClC-4A specific antibodies as well as designing high potency taste stimuli, determining taste preferences in animals, developing breed-specific foods, and modifying the taste of foods and medications.
FILED Tuesday, December 13, 2005
APPL NO 11/721597
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785808 Tracey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Feinstein Institute for Medical Research (Manhasset, New York)
INVENTOR(S) Kevin J. Tracey (Old Greenwich, Connecticut);  Hong Wang (Havertown, Pennsylvania)
ABSTRACT A method of treating a patient suffering from pancreatitis comprising treating said patient with a therapeutically effective amount of a cholinergic agonist selective for an α7 nicotinic receptor in an amount sufficient to decrease the amount of the proinflammatory cytokine that is released from a macrophage wherein said condition is acute pancreatitis. The compounds of the present invention include a quaternary analog of cocaine; (1-aza-bicyclo[2.2.2]oct-3-yl)-carbamic acid 1-(2-fluorophenyl)-ethyl ester; a compound of formula (I), a compound of formula (II), a compound of formula (III), a compound of formula (IV), and an oligonucleotide or mimetic capable of attenuating the symptoms of acute pancreatitis wherein the oligonucleotide or mimetic consists essentially of a sequence greater than 5 nucleotides long that is complementary to an mRNA of an α7 cholinergic receptor. The variables of formulae (I), (II), (III) and (IV) are described herein.
FILED Thursday, March 15, 2007
APPL NO 11/724605
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785810 Chen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Albany, New York)
INVENTOR(S) Wen-Tien Chen (Stony Brook, New York)
ABSTRACT The present invention relates to novel methods and compositions for detection and isolation of cancer cells with metastatic potential. The invention further relates to assays for measuring the metastatic potential of such cancer cells and drug screening assays for the identification of agents having anti-metastatic potential. The present invention further provides methods and compositions for inhibiting the metastatic potential of cancer cells by modulating the activity of serine integral membrane proteases [(SIMP) consisting of seprase and dipedidyl peptidase IV (DPPIV)] expressed on the surface of metastasizing cancer cells.
FILED Tuesday, August 28, 2001
APPL NO 10/220347
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785813 Gray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of California (Oakland, California)
INVENTOR(S) Joe Gray (San Francisco, California);  Graeme Hodgson (San Francisco, California);  Douglas Hanahan (San Francisco, California);  Jeffrey Hager (San Diego, California);  Oriol Casanovas (Barcelona, Spain)
ABSTRACT This invention provides methods employing prefoldin-4 (PFDN-4) nucleic acid and polypeptide sequences to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and/or for prognostic applications. Further, the invention provides methods of identifying inhibitors of PfDN-4 and methods of treating cancer by inhibiting the expression and/or activity of PFDN-4.
FILED Monday, June 19, 2006
APPL NO 11/471464
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785814 Lobanenkov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Victor V. Lobanenkov (Rockville, Maryland);  Dmitri Loukinov (Germantown, Maryland);  Ziedulla Abdullaev (Damascus, Maryland);  Svetlana Pack (N. Potomac, Maryland)
ABSTRACT The invention provides a method of detecting a proliferative disease, such as a disease associated with the abnormal expression of BORIS, in a mammal comprising detecting antibodies to BORIS in a sample obtained from the mammal. The invention also provides BORIS polypeptides as well as compositions and kits comprising the BORIS polypeptides and methods of using the same. The invention further provides a method of inducing an immune response in a mammal using BORIS polypeptides.
FILED Wednesday, September 21, 2005
APPL NO 11/575732
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785825 van der Donk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Willem A. van der Donk (Champaign, Illinois);  Lili Xie (Brookline, Massachusetts);  Champak Chatterjee (Urbana, Illinois);  Moushumi Paul (Urbana, Illinois)
ABSTRACT Lantibiotics are synthesized on ribosomes as prepeptides and post-translationally modified to a mature form. These modifications include dehydrations and cyclizations. Compounds and related methods of generating compounds, modified by dehydration, cyclization, or dehydration and cyclization, are disclosed. The disclosure includes in vitro approaches to effecting dehydration and cyclization leading to production of biologically active compounds such as lantibiotics and variants thereof. Synthetic variants and methods including combinatorial approaches for generating diverse lantibiotics and other compounds are disclosed. The invention has broad potential for applications including food, agricultural, and medical industries.
FILED Wednesday, January 12, 2005
APPL NO 11/034275
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/68.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785827 Martinis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Houston System (Houston, Texas)
INVENTOR(S) Susan A. Martinis (Houston, Texas);  James M. Briggs (Katy, Texas);  Richard S. Mursinna (Houston, Texas);  Keun Woo Lee (Houston, Texas);  Tommie L. Lincecum (Houston, Texas);  Amy M. Williams (Houston, Texas);  Yuxin Zhai (Houston, Texas)
ABSTRACT A method and composition for tRNA synthetases that activate and aminoacylate nonstandard and noncognate amino acids to tRNA adaptor molecules is described that can be used to generate custom designed protein products for uses in medicinal, therapeutic, diagnostic, biotechnology, engineering, and spectroscopy applications. Some tRNA synthetases naturally misactivate and misaminoacylate noncognate amino acids. Many of these tRNA synthetases, including but not limited to leucyl-, isoleucyl-, and valyl-tRNA synthetases, have evolved proofreading and editing mechanisms to correct these mistakes. Inactivation of the enzyme's editing activity allows and facilitates production and accumulation of tRNAs that are misaminoacylated with nonstandard and noncognate amino acids. These misaminoacylated tRNAs can be used to introduce novel amino acids into proteins.
FILED Friday, September 20, 2002
APPL NO 10/251648
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785844 Linnen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Gen-Probe Incorporated (San Diego, California)
INVENTOR(S) Jeffrey M. Linnen (Poway, California);  Daniel P. Kolk (Ramona, California);  Janel M. Dockter (Oceanside, California);  Damon K. Getman (Poway, California);  Tadashi Yoshimura (Chiba, Japan);  Martha K. Ho-Sing-Loy (San Diego, California);  Reinhold B. Pollner (San Diego, California);  Leslie A. Stringfellow (San Diego, California)
ABSTRACT Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.
FILED Monday, October 15, 2007
APPL NO 11/872538
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.510
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785857 Rezaie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Saint Louis University (Saint Louis, Missouri)
INVENTOR(S) Alireza R. Rezaie (Eureka, Missouri);  Likui Yang (St. Louis, Missouri)
ABSTRACT This invention relates to a novel form of protein C or activated protein C. More specifically, the invention is directed to a variant of protein C that is activated at a higher rate than wild-type or other variants and produces an activated protein C with reduced anticoagulant properties while retaining the protective anti-inflammatory and anti-apoptotic properties of wild-type activated protein C. This novel APC variant will be beneficial for treating inflammatory and apoptotic disorders with a reduced risk for bleeding.
FILED Thursday, August 30, 2007
APPL NO 11/848080
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/226
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785874 Wickersham et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Eye Institute (NEI)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
APPLICANT(S)
ASSIGNEE(S) The Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Ian R. Wickersham (Brookline, Massachusetts);  John A. T. Young (San Diego, California);  Edward M. Callaway (Encinitas, California)
ABSTRACT Disclosed herein are methods of expressing a heterologous nucleic acid sequence, such as a sequence encoding a detectable protein, in a primary neuron (or plurality of primary neurons) and other neurons that are monosynaptically connected to the primary neuron (or plurality of primary neurons). Such methods involve viruses (such as, rabies viruses) defective for transsynaptic transport (TST-defective virus) and in situ complementation of the defect in a manner that permits only monosynaptic transport of the TST-defective virus. The TST-defective virus and, therefore, any heterologous nucleic acid sequence it carries in its genome, are not transmitted to neurons that are not monosynaptically connected to the primary neuron (or plurality of primary neurons). Also disclosed are methods of targeting a TST-defective virus to a genetically defined primary neuron (or plurality of primary neurons). The disclosed technology enables far more specific labelling and/or manipulation of neural networks than has previously been possible.
FILED Friday, January 11, 2008
APPL NO 12/008604
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785882 Goldman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Steven A. Goldman (South Salem, New York)
ABSTRACT The present invention relates to an enriched or purified preparation of isolated hippocampal neural progenitor cells and progeny thereof. The present invention also relates to a method of separating neural progenitor cells from a mixed population of cell types from hippocampal tissue. This method includes selecting a promoter which functions selectively in the neural progenitor cells, introducing a nucleic acid molecule encoding a fluorescent protein under control of said promoter into all cell types of the mixed population of cell types from hippocampal tissue, allowing only the neural progenitor cells, but not other cell types, within the mixed population to express said fluorescent protein, identifying cells of the mixed population of cell types that are fluorescent, which are restricted to the neural progenitor cells, and separating the fluorescent cells from the mixed population of cell types, wherein the separated cells are restricted to the neural progenitor cells.
FILED Thursday, January 18, 2001
APPL NO 10/181329
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/368
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785900 Simons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico);  Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Peter C. Simons (Albuquerque, New Mexico);  Larry A. Sklar (Albuquerque, New Mexico);  Eric R. Prossnitz (Albuquerque, New Mexico);  Angela Wandinger-Ness (Albuquerque, New Mexico);  Mathewos Z. Tessema (Albuquerque, New Mexico);  John C. Reed (Ranch Santa Fe, California);  Dayong Zhai (San Diego, California)
ABSTRACT The present invention relates generally to glutathione derivatized beads which are adapted for use in conjunction with glutathione-S-transferase fusion proteins (generally, GST fusion proteins, which contain a fluorescent label such as fluorescent green protein) for use in flow cytometry. The present invention also relates to methods for detecting and/or quantifying interactions between a GST fusion protein and their binding partners, in particular, labeled binding partners such as fluorescently labeled binding partners. By creating glutathione beads with an appropriate high or increased site density, disadvantages often associated with low affinity systems and quick off-rates in solution may be resolved to provide a workable system and method. Methods of identifying potential agonists, antagonists and regulator compounds of proteins fused to GST from libraries of compounds represents another aspect of the present invention.
FILED Thursday, January 11, 2007
APPL NO 11/652432
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/523
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786072 Verdine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Gregory L. Verdine (Lexington, Massachusetts);  Christian E. Schafmeister (Somerville, Massachusetts)
ABSTRACT The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the synthesis of these compounds libraries thereof. The synthesis of these novel stabilized compounds involves (1) synthesizing a peptide from a selected number of natural or non-natural amino acids, wherein said peptide comprises at least two moieties capable of undergoing reaction to promote carbon-carbon bond formation; and (2) contacting said peptide with a reagent to generate at least one crosslinker and to effect stabilization of a secondary structure motif. The present invention, in a preferred embodiment, provides stabilized p53 donor helical peptides. Additionally, the present invention provides methods for disrupting the p53/MDM2 binding interaction comprising (1) providing a crosslinked stabilized α-helical structure; and (2) contacting said crosslinked stabilized α-helical structure with MDM2.
FILED Thursday, June 09, 2005
APPL NO 11/148976
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786074 Gourdie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) MUSC Foundation for Research Development Charleston (Charleston, South Carolina)
INVENTOR(S) Robert Gourdie (Charleston, South Carolina);  Gautam Ghatnekar (Charleston, South Carolina);  Jane Jourdan (Charleston, South Carolina)
ABSTRACT Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.
FILED Tuesday, December 20, 2005
APPL NO 11/721529
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786088 Welsh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Michael J. Welsh (Riverside, Iowa);  Paola T. Drapkin (Iowa City, Iowa)
ABSTRACT The present invention relates to the targeted delivery of a delivery vehicle construct which specifically binds to and stimulates endocytosis into cells expressing the urokinase plasminogen activator receptor (uPAR), and particularly human airway epithelia. The delivery vehicle construct comprises a portion of uPA and a cargo linked thereto and is useful for the targeted delivery of the cargo to a cell. In one aspect of the invention, the uPA portion of the delivery vehicle construct comprises the wild-type uPA, a fragment of uPA which has the PAI-1 binding region deleted, or a uPA peptide comprising amino acids 13-19 and is useful for the targeted delivery of the cargo to cells, and in particular to airway epithelia. The present invention also provides a method for delivering the delivery vehicle construct to a cell. The method comprises the steps of (a) contacting a target cell with a delivery vehicle construct comprising a uPA portion and a cargo portion; and (b) obtaining a desired result in the target cell.
FILED Wednesday, August 30, 2006
APPL NO 11/468348
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786090 Bonni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Azad Bonni (Brookline, Massachusetts);  Esther B. E. Becker (Oxford, United Kingdom)
ABSTRACT The present invention provides methods for treating or reducing neurologic disorders.
FILED Thursday, March 01, 2007
APPL NO 11/713302
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786091 Williams et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) David Williams (San Diego, California);  Xian-Jie Yang (Culver City, California)
ABSTRACT The invention provides compositions and methods for ameliorating defects in myosin VIIa (MYO7A) expression and/or function, including providing vectors for myosin VIIa expression and formulations comprising them, and methods of using them, for treating human retinitis pigmentosa (or retinal degeneration), and blindness and deafness such as that found in Usher syndrome. The invention provides in vivo gene therapy for ameliorating defects in myosin VIIa (MYO7A) expression and/or function, including compositions and methods for gene transfer of the human myosin VIIa (MYO7A) gene (the MYO7A gene.
FILED Monday, January 28, 2008
APPL NO 12/021078
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786100 Miller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Josef Miller (Ann Arbor, Michigan);  Colleen Garbe-LePrell (Ypsilanti, Michigan);  Daisuke Yamashita (Yokohama, Japan)
ABSTRACT A composition for treating hearing loss includes components that function through different biological mechanisms to provide an additive effect that is greater than the effect of the individual components alone. The composition includes a biologically effective amount of vitamin E for inhibiting propagation of lipid peroxidation that contributes to hearing loss. The composition also includes a biologically effective amount of a salicylate for reducing hydroxyl radicals that contribute to hearing loss. A method of treating hearing loss includes the step of internally administering the composition, as described above, to a mammal within three days of trauma to a middle or inner ear of the mammal. In other words, the composition is effective even when administered as late as three days after trauma to a middle or inner ear of a mammal.
FILED Monday, March 20, 2006
APPL NO 11/384579
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/159
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786162 Greig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Raptor Pharmaceutical Corp. (Novato, California);  National Institutes of Health (NIH) (Bethesda, Massachusetts)
INVENTOR(S) Nigel H. Greig (Phoenix, Maryland);  Karen T. Y. Shaw (St. Laurent, Canada);  Qiang-Sheng Yu (Lutherville, Maryland);  Harold W. Holloway (Middle River, Maryland);  Tada Utsuki (West Chester, Pennsylvania);  Timothy T. Soncrant (Silver Spring, Maryland);  Donald K. Ingram (Ellicott City, Maryland);  Arnold Brossi (Bethesda, Maryland);  Anthony Giordano (Phoenixville, Pennsylvania);  Gordon Powers (Malvern, Pennsylvania);  Diane M. Davidson (Collegeville, Pennsylvania);  Michael Sturgess (Quakertown, Pennsylvania)
ABSTRACT The present invention provides compounds and methods of administering compounds to a subject that can reduce βAPP production and that is not toxic in a wide range of dosages. The present invention also provides non-carbamate compounds and methods of administering such compounds to a subject that can reduce βAPP production and that is not toxic in a wide range of dosages. It has been discovered that either the racemic or enantiomerically pure non-carbamate compounds can be used to decrease βAPP production.
FILED Wednesday, January 21, 2009
APPL NO 12/357115
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/411
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786173 Lynch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Kevin R. Lynch (Charlottesville, Virginia);  Timothy L. Macdonald (Charlottesville, Virginia)
ABSTRACT Tetralin analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at S1P receptors.
FILED Thursday, May 21, 2009
APPL NO 12/470009
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/653
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786255 Pier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Bringham and Women's Hospital, Inc. (Boston, Massachusetts);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Gerald B. Pier (Brookline, Massachusetts);  Casie Anne Kelly-Quintos (Boston, Massachusetts);  Lisa Cavacini (Natick, Massachusetts);  Marshall R. Posner (Medfield, Massachusetts)
ABSTRACT The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to poly-N-acetyl glucosamine (PNAG), such as Staphylococcal PNAG, in acetylated, partially acetylated and/or fully deacetylated form. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of infections by bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Some antibodies of the invention enhance opsonophagocytic killing and in vivo protection against bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides.
FILED Thursday, April 21, 2005
APPL NO 11/111688
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786259 Gutheil
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) William G. Gutheil (Kansas City, Missouri)
ABSTRACT The present invention provides a process for preparing an immobilized peptide derivative of formula (Vb):
comprising reacting a functionalized solid support comprising Sub-L wherein Sub is a solid support and L is a cleavable linker, with H—[NH—A—C(O)]—O(tBu), then reacting the immobilized product with compound of the formula RHN—A—C(O)OH, wherein the RHN—A—C(O) group is the residue of a N-protected α-amino acid, in the presence of a coupling agent, to yield an immobilized peptide derivative of the formula (Vb).
FILED Friday, July 13, 2007
APPL NO 11/777899
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/334
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786267 Zurawski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Baylor Research Institute (Dallas, Texas)
INVENTOR(S) Gerard Zurawski (Midlothian, Texas);  Anne-Laure Flamar (Dallas, Texas);  Eynav Klechevsky (Dallas, Texas)
ABSTRACT The present invention includes compositions and methods for designing, making and using modular recombinant antibodies or fragments thereof with one half of a cohesin-dockerin pair that permits the rapid assembly of multivariant antigen conjugates.
FILED Thursday, January 31, 2008
APPL NO 12/024036
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786275 Rangnekar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Vivek M. Rangnekar (Lexington, Kentucky)
ABSTRACT The present invention relates to Par-4 mutants which cause apoptosis in cancer cells which are sensitive to Par-4 and also induce apoptosis in cancer cells which are resistant to Par-4. The present invention also relates to methods of using the Par-4 mutant to treat certain cancers, as well as to kits, vectors, and polypeptides for same.
FILED Thursday, December 04, 2003
APPL NO 10/726615
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/388.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786298 Barton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jacqueline K. Barton (San Marino, California);  Brian Zeglis (Pasadena, California);  Irvin H. Lau (Pasadena, California);  Jonathan Hart (San Diego, California);  Mi Hee Lim (San Diego, California)
ABSTRACT In accordance with the present invention there are provided sterically demanding intercalators. These compounds are useful for detection of a base-pair mismatch, such as by measuring fluorescence of complexes formed by the compounds of the invention and nucleic acid duplexes. The compounds are also capable of catalyzing photolytic cleavage of nucleic acids.
FILED Friday, January 12, 2007
APPL NO 11/653068
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
544/225
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786316 Puerta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of California (Oakland, California)
INVENTOR(S) David T. Puerta (Melrose, Massachusetts);  Seth M. Cohen (San Marcos, California);  Jana A. Lewis (La Jolla, California)
ABSTRACT The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I):
wherein X is O or S and each R1, R2, R3, and R4 is individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.
FILED Wednesday, July 15, 2009
APPL NO 12/503190
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/418
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786347 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Burnham Institute for Medical Research (La Jolla, California)
INVENTOR(S) Qihong Huang (San Diego, California);  John C. Reed (Rancho Santa Fe, California);  Bruce D. Hammock (Davis, California);  Quinn L. Deveraux (San Diego, California);  Susumu Maeda (Pasadena, California);  Hiroko Maeda, legal representative (Pasadena, California)
ABSTRACT The invention provides polypeptides comprising inhibitor of apoptosis protein (IAP) family members, such as BmIAP initially derived from Bombyx mori BmN cells, and nucleic acids encoding them, and methods for making and using these compositions, including their use for inhibiting apoptosis.
FILED Tuesday, January 16, 2007
APPL NO 11/623637
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/279
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786729 Chamberlain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (St. Paul, Minnesota)
INVENTOR(S) Ryan Chamberlain (New Brighton, Minnesota);  Jang-Yeon Park (Minneapolis, Minnesota);  Michael G. Garwood (Medina, Minnesota)
ABSTRACT A method of magnetic resonance imaging based on rapid acquisition by sequential excitation and refocusing is provided. The method comprises turning on a first time-encoding gradient and applying an excitation pulse in the presence of the first time-encoding gradient. The excitation pulse excites magnetization sequentially along one spatial axis. Thereafter, a first refocusing pulse is applied. A second time-encoding gradient is turned on followed by a second refocusing pulse. A third time-encoding gradient is turned on and a signal is acquired in the presence of the third time-encoding gradient. The third time-encoding gradient sums to zero with the first time-encoding gradient and the second time-encoding gradient for sequential points in space.
FILED Wednesday, October 31, 2007
APPL NO 11/931968
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787106 Ilev et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ilko K. Ilev (Rockville, Maryland);  Ronald A. Robinson (Germantown, Maryland);  Ronald W. Waynant (Clarksville, Maryland)
ABSTRACT An illumination system for a particle image velocimetry system has an illumination source, a hollow tapered optical funnel arranged to receive illumination light from the illumination source, a hollow optical waveguide optically coupled to an output end of the hollow tapered optical funnel, and a beam shaping optical system optically coupled to an output end of the hollow optical waveguide. The illumination system is constructed to provide a light sheet to illuminate particles within a fluid under observation. A particle image velocimetry system has such an illumination system.
FILED Monday, October 30, 2006
APPL NO 11/589310
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/27
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787129 Zysk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Adam M. Zysk (Chicago, Illinois);  Steven G. Adie (Belmont, Washington);  Matthew S. Leigh (Carlisle, Washington);  Julian J. Armstrong (Carlisle, Washington);  David D. Sampson (Fremantle, Washington);  Stephen A. Boppart (Champaign, Illinois)
ABSTRACT A method of analyzing tissue includes inserting a radiation source into tissue, impinging radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the tissue, and determining a refractive index of the tissue from the sample signal. The method may also include determining at least one other optical property of the tissue. The method may provide for identifying tissue as part of a biopsy method. A device for analyzing tissue may include a low-coherence interferometer and a probe optically coupled to the interferometer, where the probe includes a radiation source.
FILED Wednesday, January 31, 2007
APPL NO 11/669561
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/481
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787681 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Jian Zhang (New York, New York);  Alessio Salerno (Montreal, Canada);  Nabil Simaan (New York, New York);  Y. Lawrence Yao (New York, New York);  Gerhard Randers-Pehrson (Ossining, New York);  Guy Garty (Dobbs Ferry, New York);  Aparajita Dutta (Waltham, Massachusetts);  David J. Brenner (New York, New York)
ABSTRACT Systems and methods for robotic transport are disclosed herein. In some embodiments, robotic systems for transporting biological samples include: a plurality of capillary vessels, in which each capillary vessel can contain a biological sample from a population; a receptacle that can contain the plurality of capillary vessels; a centrifuge; a first robotic device that can transport the receptacle between an input module and the centrifuge; a second robotic device that can transport the receptacle between the centrifuge and a sample harvest location; a cutting device that can cut each of the plurality of capillary vessels; a multi-well plate having a plurality of wells arranged in an array; and a third robotic device that can transfer at least one portion of each of the plurality of biological samples from each of the plurality of capillary vessels to a corresponding well in the array.
FILED Friday, August 24, 2007
APPL NO 11/895485
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787930 Nezafat et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Reza Nezafat (Bethesda, Maryland);  Ronald Ouwerkerk (Baltimore, Maryland);  Matthias Stuber (Ellicott City, Maryland)
ABSTRACT Adiabatic pulses that define an amplitude modulation and a frequency modulation are applied in a sequence of pulses to obtain a T2 weighted magnetic resonance image. Such an adiabatic T2 prep sequence typically includes a first 90° pulse, an even number of adiabatic pulses, and a second 90° pulse. Adiabatic pulses can be selected based on function pairs, or can be defined numerically. A magnetic resonance imaging (MRI) system includes a library of adiabatic pulse waveforms, and is configured to select a waveform and apply an RF magnetic field based on the selected pulse waveform.
FILED Monday, June 06, 2005
APPL NO 11/147151
ART UNIT 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Surgery
6/410
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07788075 DeYoe et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) MCW Research Foundation (Milwaukee, Wisconsin)
INVENTOR(S) Edgar A. DeYoe (Delafield, Wisconsin);  John L. Ulmer (Brookfield, Wisconsin);  Rachael A. Kirchhoff (Milwaukee, Wisconsin)
ABSTRACT A visual defect simulation system receives a functional field map produced by an MRI system that relates locations in a patient's brain to locations in the patient's field of view. Planned medical operations are indicated at locations in the patient's brain and any resulting vision loss is simulated with a revised functional field map. A scene is displayed and an impairment overlay is produced from the revised functional field map that blocks the scene at locations corresponding to simulated vision loss. The overlay is translated over the scene in response to viewer eye movements detected by a vision-tracking system to present a real-time simulation of the resulting vision loss.
FILED Monday, August 15, 2005
APPL NO 11/203754
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/11
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE41614 Corey
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Elias J. Corey (Cambridge, Massachusetts)
ABSTRACT The present invention is directed to the synthesis and characterization of compounds having the formula: wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from the group consisting of H, OH, OR′, SH, SR′, SOR′, SO2R′, NO2, NH2, NHR′, N(R′)2, NHC(═O)R′ NHC(═O)R′, CN, halogen, ═O, C(═O)H, C(═O)R′, CO2H, CO2R′, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, and substituted or unsubstituted heteroaromatic; wherein each of the R′ groups is independently selected from the group consisting of H, OH, NH2, NO2, SH, CN, halogen, ═O, C(═O)H, C(═O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, aralkyl, and heteroaromatic; wherein each dotted circle represents one, two or three optional double bonds; wherein R7 and R8 may be are joined into a carbocyclic or heterocyclic ring system; and wherein X1 and X2 are each independently defined as above for R1-R8 R1-R6 and R9, and each further includes specific preferred groups as defined herein.
FILED Wednesday, December 17, 2003
APPL NO 10/738973
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/250
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 07784263 Ponziani
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Robert Louis Ponziani (West Chester, Ohio)
ABSTRACT A method for determining sensor locations in a gas turbine engine is provided. The said method includes providing a turbine rear frame including a radially inner surface, a radially outer surface and a plurality of circumferentially-spaced struts extending between the inner and outer surfaces, wherein a strut sector is defined between each pair of circumferentially-adjacent struts, providing a plurality of fuel nozzles that are each aligned with a strut sector, selecting one of the plurality of fuel nozzles as a primary index nozzle and positioning each of a plurality of sensors relative to one of the plurality of nozzles using a corresponding positioning angle such that each of the plurality of sensors coincides with a gas flow temperature distribution profile between each pair of circumferentially-spaced nozzles.
FILED Tuesday, December 05, 2006
APPL NO 11/567088
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/39.240
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07784570 Couture et al.
FUNDED BY
Department of Defense (DOD)
Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC)
Technical Support Working Group (TSWG)
APPLICANT(S)
ASSIGNEE(S) iRobot Corporation (Bedford, Massachusetts)
INVENTOR(S) Adam P. Couture (Allston, Massachusetts);  Richard Page (Middleton, Massachusetts);  John P. O'Brien (Newton, Massachusetts);  Mikhail Filippov (Arlington, Massachusetts)
ABSTRACT A robotic vehicle is disclosed, which is characterized by high mobility, adaptability, and the capability of being remotely controlled in hazardous environments. The robotic vehicle includes a chassis having front and rear ends and supported on right and left driven tracks. Right and left elongated flippers are disposed on corresponding sides of the chassis and operable to pivot. A linkage connects a payload deck, configured to support a removable functional payload, to the chassis. The linkage has a first end rotatably connected to the chassis at a first pivot, and a second end rotatably connected to the deck at a second pivot. Both of the first and second pivots include independently controllable pivot drivers operable to rotatably position their corresponding pivots to control both fore-aft position and pitch orientation of the payload deck with respect to the chassis.
FILED Monday, August 06, 2007
APPL NO 11/834658
ART UNIT 3611 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Motor vehicles
180/9.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07784583 Hall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) John Allan Hall (Beavercreek, Ohio);  Karl Cartwright (Colorado Springs, Colorado);  Kris Cartwright (Colorado Springs, Colorado)
ABSTRACT A deep insertion vented earpiece system is described including resilient earpieces shaped to a wearer's ear canal for a conformal fit. A receptacle is provided within the outer surface of each earpiece for releasably receiving an audio plug. The audio plugs include a miniature loudspeaker and a pair of external ribs for mating with a corresponding pair of grooves formed along the periphery of the receptacle. This rib and groove feature provides for a secure retention of the audio plugs while enabling a simple removal operation. Each earpiece includes an audio passage to conduct the audio signal from the loudspeaker and a vent passage to enable continuous venting of the wearer's ear to atmosphere.
FILED Monday, April 24, 2006
APPL NO 11/417281
ART UNIT 2832 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Acoustics
181/130
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US 07784621 Pinnau
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S)
ASSIGNEE(S) Membrane Technology and Research, Inc (Menlo Park, California)
INVENTOR(S) Ingo Pinnau (Palo Alto, California)
ABSTRACT An inorganic membrane suitable for ultrafiltration or nanofiltration, and methods for making and using the membrane. The membrane has a organic polymer deposited on the feed surface, but is not able to perform separations by solution-diffusion.
FILED Tuesday, June 29, 2004
APPL NO 10/879628
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Liquid purification or separation
210/510.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785067 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ching-Pang Lee (Cincinnati, Ohio);  Eric Alan Estill (Morrow, Ohio);  James Harvey Laflen (Loveland, Ohio);  Paul Hadley Vitt (Hamilton, Ohio);  Michael Elliot Wymore (Madison, Alabama)
ABSTRACT A method of assembling a gas turbine engine is provided. The method includes coupling at least one turbine nozzle segment within the gas turbine engine. The at least one turbine nozzle segment includes at least one airfoil vane extending between an inner band and an outer band that includes an aft flange and a radial inner surface. The method also includes coupling at least one turbine shroud segment downstream from the at least one turbine nozzle segment, wherein the at least one turbine shroud segment includes a leading edge and a radial inner surface, and coupling a cooling fluid source in flow communication with the at least one turbine nozzle segment such that cooling fluid channeled to each turbine nozzle outer band aft flange is directed at an oblique discharge angle towards the leading edge of the at least one turbine shroud segment.
FILED Thursday, November 30, 2006
APPL NO 11/565229
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/173.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785496 Shim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Clemson University Research Foundation (Anderson, South Carolina)
INVENTOR(S) Goo Hwan Shim (Pendleton, South Carolina);  Moon Gyu Han (Dunlap, Illinois);  Stephen H. Foulger (Clemson, South Carolina)
ABSTRACT Disclosed are electrochromic inks and devices incorporating the inks as well as methods for forming the inks and the devices. The disclosed inks include a dispersion of colloidal nanocomposite particles in a liquid carrier. The colloidal nanocomposites of the disclosed inks include nanoparticle templates, e.g., silica nanoparticles, and an intrinsically conductive polymer polymerized at the template nanoparticles. The inks can include a dispersion of the colloidal nanocomposites in a liquid carrier such as an aprotic polar organic solvent. The disclosed inks can be formulated to be utilized in any desired printing process such as inkjet printing processes. Products encompassed by the invention include all-polymer electronic, optic, photonic, electro-optic, and energy devices such as sensors, OFETs, RFID tags, printed circuit board, electrochromic devices, non-volatile memory devices, photovoltaics, and the like.
FILED Thursday, January 24, 2008
APPL NO 12/019084
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785656 Pei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Qibing Pei (Temecula, California);  Ronald E. Pelrine (Louisville, Colorado);  Marcus Rosenthal (Pacifica, California)
ABSTRACT The present invention provides electroactive polymers, transducers and devices that maintain pre-strain in one or more portions of an electroactive polymer. Electroactive polymers described herein may include a pre-strained portion and a stiffened portion configured to maintain pre-strain in the pre-strained portion. One fabrication technique applies pre-strain to a partially cured electroactive polymer. The partially cured polymer is then further cured to stiffen and maintain the pre-strain. In another fabrication technique, a support layer is coupled to the polymer that maintains pre-strain in a portion of an electroactive polymer. Another embodiment of the invention cures a polymer precursor to maintain pre-strain in an electroactive polymer.
FILED Tuesday, August 19, 2008
APPL NO 12/194340
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/58
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785737 Teeters
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The University of Tulsa (Tulsa, Oklahoma)
INVENTOR(S) Dale Teeters (Sand Springs, Oklahoma)
ABSTRACT A sequence or array of electrochemical cells storing both digital and analog data. Both binary code and codes having a higher base may be stored in the memory device to increase information density. Such battery arrays could also provide power for the micro or nanodevice. Devices are microscale and nanoscale in size and utilize an electrical crossbar system to record and read data stored in the device.
FILED Wednesday, January 17, 2007
APPL NO 11/624073
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785769 Spector et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as reprsented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Mark S. Spector (Springfield, Virginia);  David A. Stenger (Herndon, Virginia);  Charles H. Patterson, Jr. (Glen Burnie, Maryland);  Brett D. Martin (Washington, District of Columbia);  Paul T. Charles (Bowie, Maryland)
ABSTRACT The use of sugar-containing hydrogels as very highly porous, aqueous support material for the immobilization of oligonucleotides, peptides, proteins, antigens, antibodies, polysaccharides, and other biomolecules for sensor applications. Unusually large sizes of interconnected pores allow large target molecules to pass rapidly into and through the gel and bind to immobilized biomolecules. Sugar-containing hydrogels have extremely low non-specific absorption of labeled target molecules, providing low background levels. Some hydrogel materials do not have this type of homogeneous interconnected macroporosity, thus large target molecules cannot readily diffuse through them. Additionally, they nearly always experience non-specific absorption of labeled target molecules, limiting their usefulness in sensor applications. A method is provided for preparing sugar polyacrylate hydrogels with functional chemical groups which covalently bond oligonucleotides and peptides. A method for copolymerizing acrylate-terminated oligonucleotides with sugar acrylate monomers and diacrylate cross-linking agents is also provided.
FILED Friday, July 25, 2003
APPL NO 10/627143
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785770 Spector et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Mark S. Spector (Springfield, Virginia);  David A. Stenger (Herndon, Virginia);  Charles H. Patterson, Jr. (Glen Burnie, Maryland);  Brett D. Martin (Washington, District of Columbia);  Paul T. Charles (Bowie, Maryland)
ABSTRACT The use of sugar-containing hydrogels as very highly porous, aqueous support material for the immobilization of oligonucleotides, peptides, proteins, antigens, antibodies, polysaccharides, and other biomolecules for sensor applications. Unusually large sizes of interconnected pores allow large target molecules to pass rapidly into and through the gel and bind to immobilized biomolecules. Sugar-containing hydrogels have extremely low non-specific absorption of labeled target molecules, providing low background levels. Some hydrogel materials do not have this type of homogeneous interconnected macroporosity, thus large target molecules cannot readily diffuse through them. Additionally, they nearly always experience non-specific absorption of labeled target molecules, limiting their usefulness in sensor applications. A method is provided for preparing sugar polyacrylate hydrogels with functional chemical groups which covalently bond oligonucleotides and peptides. A method for copolymerizing acrylate-terminated oligonucleotides with sugar acrylate monomers and diacrylate cross-linking agents is also provided.
FILED Friday, May 19, 2006
APPL NO 11/444819
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786024 Stumbo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Nanosys, Inc. (Palo Alto, California);  Regents of the University of California (Oakland, California)
INVENTOR(S) David P. Stumbo (Belmont, California);  Yaoling Pan (Princeton, New Jersey);  Costas P. Grigoropoulos (Berkeley, California);  Nipun Misra (Berkeley, California)
ABSTRACT Methods, systems, and apparatuses for annealing semiconductor nanowires and for fabricating electrical devices are provided. Nanowires are deposited on a substrate. A plurality of electrodes is formed. The nanowires are in electrical contact with the plurality of electrodes. The nanowires are doped. A polarized laser beam is applied to the nanowires to anneal at least a portion of the nanowires. The nanowires may be aligned substantially parallel to an axis. The laser beam may be polarized in various ways to modify absorption of radiation of the applied laser beam by the nanowires. For example, the laser beam may be polarized in a direction substantially parallel to the axis or substantially perpendicular to the axis to enable different nanowire absorption profiles.
FILED Wednesday, November 07, 2007
APPL NO 11/936590
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/795
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786071 Tawfik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) Yeda Research And Development Co. Ltd. (Rehovot, Israel)
INVENTOR(S) Dan S. Tawfik (Jerusalem, Israel);  Amir Aharoni (Tel Aviv, Israel);  Leonid Gaydukov (Rehovot, Israel);  Joel L. Sussman (Rehovot, Israel);  Israel Silman (Rehovot, Israel)
ABSTRACT Isolated polynucleotides and polypeptides encoded therefrom are provided. These include mutated PON enzymes with increased, modified or substantially the same substrate specificity as compared to respective wild-type PON. Also provided are kits and methods using these enzymes.
FILED Thursday, March 04, 2004
APPL NO 10/547771
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786285 Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Leonard A. Smith (Clarksburg, Maryland);  Michael P. Byrne (New Market, Maryland);  John L. Middlebrook (Middletown, Maryland);  Hugh Lapenotiere (Charlestown, West Virginia);  Michael A. Clayton (Mt. Airy, Maryland);  Douglas R. Brown (Gaithersburg, Maryland)
ABSTRACT This invention is directed to preparation and expression of synthetic genes encoding polypeptides containing protective epitopes of botulinum neurotoxin (BoNT). The invention is also directed to production of immunogenic peptides encoded by the synthetic genes, as well as recovery and purification of the immunogenic peptides from recombinant organisms. The invention is also directed to methods of vaccination against botulism using the expressed peptides.
FILED Friday, May 19, 2006
APPL NO 11/437212
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786438 DeVilbiss et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Airforce (Washington, District of Columbia)
INVENTOR(S) Nathan DeVilbiss (Sandia Park, New Mexico);  Ryan Olcott (Rio Rancho, New Mexico);  Peter Thomas (Albuquerque, New Mexico);  Gregory Spanjers (Sandia Park, New Mexico);  James Winter (Albuquerque, New Mexico);  Jason Guarnieri (Albuquerque, New Mexico);  Timothy Klatt (Albuquerque, New Mexico);  Holly Victorson (Albuquerque, New Mexico);  Thomas Roberts (Albuquerque, New Mexico);  Robert Thompson (Marina Del Rey, California)
ABSTRACT A sensor assembly that replaces a single focal plane array detector with two focal plane array detectors orientated with respect to each other such that a power splitter divides an incoming light source equally between each detector. The two detectors are selected such that the locations of poorly-operating pixels in each detector do not overlay. The output signals of each detector are then electronically or analytically combined to yield 100 percent operability. Separate switchable wavelength filter wheels having one or more different wavelength filters may be positioned between the power splitter and each of the detectors. The power splitter may be replaced by a polarization splitter. One detector can be translated perpendicular to the incoming light source relative to the second detector to compensate for new poorly-operating pixels and/or to improve the spatial resolution.
FILED Monday, July 21, 2008
APPL NO 12/176490
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/332
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786467 Williams et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S) R. Stanley Williams (Portola Valley, California);  Philip J. Kuekes (Menlo Park, California)
ABSTRACT Various embodiments of the present invention include three-dimensional, at least partially nanoscale, electronic circuits and devices in which signals can be routed in three independent directions, and in which electronic components can be fabricated at junctions interconnected by internal signal lines. The three-dimensional, at least partially nanoscale, electronic circuits and devices include layers, the nanowire or microscale-or-submicroscale/nanowire junctions of each of which may be economically and efficiently fabricated as one type of electronic component. Various embodiments of the present invention include nanoscale memories, nanoscale programmable arrays, nanoscale multiplexers and demultiplexers, and an almost limitless number of specialized nanoscale circuits and nanoscale electronic components.
FILED Monday, April 25, 2005
APPL NO 11/114307
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/17
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786596 Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Kuan-Neng Chen (White Plains, New York);  Bruce K. Furman (Pouquag, New York);  Edmund J. Sprogis (Underhill, Vermont);  Anna W. Topol (Jefferson Valley, New York);  Cornelia K. Tsang (Mohegan Lake, New York);  Matthew R. Wordeman (Kula, Hawaii);  Albert M. Young (Fishkill, New York)
ABSTRACT A sealed microelectronic structure which provides mechanical stress endurance and includes at least two chips being electrically connected to a semiconductor structure at a plurality of locations. Each chip includes a continuous bonding material along it's perimeter and at least one support column connected to each of the chips positioned within the perimeter of each chip. Each support column extends outwardly such that when the at least two chips are positioned over one another the support columns are in mating relation to each other. A seal between the at least two chips results from the overlapping relation of the chip to one another such that the bonding material and support columns are in mating relation to each other. Thus, the seal is formed when the at least two chips are mated together, and results in a bonded chip structure.
FILED Wednesday, February 27, 2008
APPL NO 12/038501
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/777
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786645 Gamble et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) American Superconductor Corporation (Devens, Massachusetts)
INVENTOR(S) Bruce B. Gamble (Wellesley, Massachusetts);  Gregory L. Snitchler (Shrewsbury, Massachusetts);  Darrell Morrison (Blaine, Minnesota)
ABSTRACT A stator for an electrical machine includes a back iron including a substantially cylindrical annular structure having an inner surface and an axis. A plurality of supports are fabricated of non-magnetic material, each support extending parallel to the axis of the annular structure along the inner surface of the annular structure, each support including a primary base and at least two primary support members. The primary bases substantially conform to the inner surface of the back iron with the primary support members extending radially inward from the primary base towards the axis of the annular structure. A stator winding is positioned between the at least two primary support members and between the primary base of the support and the axis of the annular structure.
FILED Thursday, September 07, 2006
APPL NO 11/516970
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/216.5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786716 Simburger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (, California)
INVENTOR(S) Edward J. Simburger (Agoura Hills, California);  Daniel L. Rumsey (Inglewood, California);  Peter J. Carian (Inglewood, California)
ABSTRACT A solar cell regulator in a nanosatellite includes a pulse width modulated DC-DC boost converter and a peak power tracking controller for converting solar cell power to bus power for charging of system batteries and powering loads while the controller controls the pulse width modulation operation of the converter for sensing solar cell currents and voltages along a power characteristic curve of the solar cell for peak power tracking, for determining any power data point, including a peak power point, an open circuit voltage point, and a short circuit current point along the power characteristic curve of the solar cell, and for communicating the power data to a satellite processor for monitoring the performance of the solar cell during operational use of the satellite.
FILED Monday, August 29, 2005
APPL NO 11/214377
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Power supply or regulation systems
323/290
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786736 Thostenson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) University of Delaware (Newark, Delaware)
INVENTOR(S) Erik T. Thostenson (Newark, Delaware);  Tsu-Wei Chou (Newark, Delaware)
ABSTRACT Methods and structural defect detectors for detecting a structural defect in composites are presented. An exemplary method includes forming a nanocomposite including a plurality of nanotubes mechanically aligned in a principal direction within a polymer matrix. A voltage is applied to the nanocomposite and a resistance of the nanocomposite is measured using the applied voltage to detect the structural defect. An exemplary structural defect detector includes a nanocomposite including a plurality of mechanically aligned nanotubes within the polymer matrix, electrodes coupled to the nanocomposite, a voltage source for applying a voltage to the electrodes, and a resistance detector for measuring a resistance of the nanocomposite that allows identification of a structural defect. The plurality of nanotubes form a conducting percolating network of sensors.
FILED Tuesday, October 02, 2007
APPL NO 11/906366
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/525
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787030 Fridrich et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Binghamton, New York)
INVENTOR(S) Jessica Fridrich (Vestal, New York);  Miroslav Goljan (Vestal, New York);  Jan Lukas (Johnson City, New York)
ABSTRACT A new technique for identifying from images a camera, or other imaging device such as a scanner, is based on the device's reference noise pattern, a unique stochastic characteristic of all common digital imaging sensors, including CCD, CMOS (Foveon™ X3), and JFET. First, one determines from images the sensor's reference pattern noise, which uniquely identifies each sensor. To identify the sensor from a given image, the presence or absence of the reference pattern noise in the image under examination is established using a correlation detector or other means.
FILED Friday, December 16, 2005
APPL NO 11/305611
ART UNIT 2622 — Selective Visual Display Systems
CURRENT CPC
Television
348/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787285 Chuang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Ching-Te Chuang (South Salem, New York);  Jae-Joon Kim (Yorktown Heights, New York);  Keunwoo Kim (Somers, New York)
ABSTRACT Techniques are provided for employing independent gate control in asymmetrical memory cells. A memory circuit, such as an SRAM circuit, can include a number of bit line structures, a number of word line structures that intersect the bit line structures to form a number of cell locations, and a number of asymmetrical memory cells located at the cell locations. Each of the asymmetrical cells can be selectively coupled to a corresponding one of the bit line structures under control of a corresponding one of the word line structures. Each of the cells can include a number of field effect transistors (FETS), and at least one of the FETS can be configured with separately biased front and back gates. One gate can be biased separately from the other gate in a predetermined manner to enhance read stability of the asymmetrical cell.
FILED Tuesday, June 17, 2008
APPL NO 12/140366
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/154
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787331 Barger et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) BBN Technologies, Corp. (Cambridge, Massachusetts)
INVENTOR(S) James E. Barger (Winchester, Massachusetts);  John Stanley (Wilmington, Massachusetts)
ABSTRACT A sensor assembly suitable for use in an airborne shooter localization system. The sensor assembly has a pressure sensor subassembly with a pressure transducer positioned to detect pressure variations associated with a shock wave from a passing projectile or the muzzle blast following the shock wave. To substantially increase the signal to noise ratio for measurements of the shock wave, the pressure sensor subassembly attenuates pressure fluctuations triggered by turbulent airflow over the surface of the subassembly more than it attenuates the shock wave. This preferential attenuation is provided by separating the pressure transducer from the surface of the sensor assembly by a cavity large enough that the pressure fluctuations are substantially attenuated as they propagate across the cavity. Additionally, features of a housing that holds the pressure sensor subassembly facilitate use on an aircraft. Those features include flexibility that allows the sensor assembly to conform to curved surfaces, a skin that provides resistance to environmental conditions and allows the sensor assembly to be attached with an adhesive, and a body region that provides high vibrational impedance to prevent low frequency mechanical vibrations from being coupled to the pressure transducer.
FILED Tuesday, May 13, 2008
APPL NO 12/119783
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/188
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787426 Seidel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Powerwave Cognition, Inc. (Santa Ana, California)
INVENTOR(S) Scott Y. Seidel (Fairfax, Virginia);  Jay N. Livingston (Oakton, Virginia);  Michael R. Franceschini (Centerport, New York)
ABSTRACT Establishing communications between a plurality of nodes includes determining a set of frequencies to search for neighbor nodes, and performing an adaptive control channel initialization operation to detect zero or more neighbor nodes. If one or neighbor nodes are detected, an adaptive control channel with one or more of the one or more detected neighbor nodes is established.
FILED Friday, November 10, 2006
APPL NO 11/595740
ART UNIT 2617 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Multiplex communications
370/338
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787450 Chan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) ITT Manufacturing Enterprises, Inc (Wilmington, Delaware)
INVENTOR(S) Chi Chiu Chan (Wayne, New Jersey);  Amit Patel (Edison, New Jersey)
ABSTRACT An efficient network formation technique for mobile ad-hoc wireless networks according to the present invention overcomes bandwidth overhead due to generation of database update or Link State Advertisement (LSA) messages in response to changes in certain parameters (e.g., node group size, etc.) with respect to both single and plural node group scenarios. The present invention controls flooding of LSA messages triggered by changes in these parameters (e.g., node group size), thereby reducing overhead traffic during network start-up. This is achieved without impact on message delivery capability and group merge operations. After network start-up is complete and the network is formed, the present invention continues to reduce LSA flooding in a mobile scenario when radios or nodes move into and out of range with one another.
FILED Wednesday, October 11, 2006
APPL NO 11/545587
ART UNIT 2475 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Multiplex communications
370/389
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787646 Pelrine et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Ronald E. Pelrine (Louiseville, Colorado);  Roy D. Kornbluh (Palo Alto, California);  Harsha Prahlad (Cupertino, California)
ABSTRACT The present invention provides electroactive polymer transducers that produce out-of-plane deflections. The transducers form a set of surface features based on deflection of an electroactive polymer. The set of surface features may include elevated polymer surface features and/or depressed electrode surface features. Actuation of an active area may produce the polymer deflection that creates one or more surface features. A passive layer may operably connect to a polymer. The passive layer may comprise a thicker and softer material to amplify polymer thickness changes and increase surface feature visibility.
FILED Sunday, July 29, 2007
APPL NO 11/829915
ART UNIT 2614 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Electrical audio signal processing systems and devices
381/191
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787652 Fridrich et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Jessica Fridrich (Vestal, New York);  Miroslav Goljan (Johnson City, New York);  Rui Du (Johnson City, New York)
ABSTRACT Current methods of embedding hidden data in an image inevitably distort the original image by noise. This distortion cannot generally be removed completely because of quantization, bit-replacement, or truncation at the grayscales 0 and 255. The distortion, though often small, may make the original image unacceptable for medical applications, or for military and law enforcement applications where an image must be inspected under unusual viewing conditions (e.g., after filtering or extreme zoom). The present invention provides high-capacity embedding of data that is lossless (or distortion-free) because, after embedded information is extracted from a cover image, we revert to an exact copy of the original image before the embedding took place. This new technique is a powerful tool for a variety of tasks, including lossless robust watermarking, lossless authentication with fragile watermarks, and steganalysis. The technique is applicable to raw, uncompressed formats (e.g., BMP, PCX, PGM, RAS, etc.), lossy image formats (JPEG, JPEG2000, wavelet), and palette formats (GIF, PNG).
FILED Tuesday, July 03, 2007
APPL NO 11/773263
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787779 Weiner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Andrew M. Weiner (West Lafayette, Indiana);  Jason D. McKinney (Waldorf, Maryland)
ABSTRACT A photonic waveform generator and system is described. The photonic waveform generator is used in produce an electrical pulse having arbitrarily controllable temporal characteristics in a Fourier transform (FT) pulse shaper or a direct space-to-time (DST) photonic generator. The electrical pulse signal may be used in a radar, a telecommunications system or other electrical apparatus where the spectral and temporal characteristics of the signal are be optimized with respect to specific system needs, such as spectral occupancy, peak-to-average power, minimum pulse duration, target-to-clutter ratio, target type discrimination, and the like.
FILED Thursday, May 04, 2006
APPL NO 11/418585
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/201
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07788209 Paquet et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Michel D. Paquet (Milton, Florida);  Baban V. Baliga (Glastonbury, Connecticut);  Ravi Rajamani (West Hartford, Connecticut);  Andrew Paul Gagnon (West Hartford, Connecticut)
ABSTRACT A fault reasoning system combines both a model-based reasoning approach based upon predicted root causes of a plurality of fault signals, and a case-based reasoner that looks at the actual root cause of actual cases.
FILED Monday, May 05, 2008
APPL NO 12/114896
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/52
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07788332 Manohar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Rajit Manohar (Ithaca, New York);  Clint Kelly (Ithaca, New York)
ABSTRACT Event-driven processor architectures are particularly suited for use in multiple sensor node networks and simulators of such networks. A first variation of the processor is particularly suited for use in a sensor node in a wireless sensor network. Through use of the event-driven architecture and special message and timing coprocessors, this embodiment of the invention is optimized for low energy requirements and data monitoring operations in sensor networks. A second embodiment of the invention includes modifications necessary for use of the processor in a network simulation protocol.
FILED Friday, May 06, 2005
APPL NO 11/123234
ART UNIT 2456 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/207
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE41607 Lui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Gee L. Lui (Westminster, California);  Kuang Tsai (Santa Ana, California)
ABSTRACT Data aided carrier phase and symbol timing synchronizers are implemented at baseband as digital modulators isolating input signal inphase and quadrature component signals fed into inphase and quadrature. Laurent transforms that function as data detector to provide odd and even data bit multiplexed output data signal while cross coupling the inphase and quadrature transformed outputs for removing data modulation in error signals to correct phase errors and timing errors in the received signal so as to provide reliable data demodulation of noisy received signals having dynamic carrier phase and symbol timing errors as found in continuous phase modulation communications systems such as Gaussian minimum shift keying communications systems.
FILED Wednesday, February 28, 2007
APPL NO 11/713119
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE41613 Jain et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Ravinder Jain (Albuquerque, New Mexico);  Balaji Srinivasan (Mandaveli, Chennai, India)
ABSTRACT The present invention relates generally to electro-optically active waveguide segments, and more particularly to the use of a selective voltage input to control the phase, frequency and/or amplitude of a propagating wave in the waveguide. Particular device structures and methods of manufacturing are described herein.
FILED Wednesday, May 24, 2006
APPL NO 11/440781
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/321
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07785070 Liang
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) George Liang (Palm City, Florida)
ABSTRACT An airfoil including an outer wall and a cooling cavity formed therein. The cooling cavity includes a leading edge flow channel located adjacent a leading edge of the airfoil and a trailing edge flow channel located adjacent a trailing edge of the airfoil. Each of the leading edge and trailing edge flow channels define respective first and second flow axes located between pressure and suction sides of the airfoil. A plurality of rib members are located within each of the flow channels, spaced along the flow axes, and alternately extending from opposing sides of the flow channels to define undulating flow paths through the flow channels.
FILED Tuesday, March 27, 2007
APPL NO 11/728884
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/97.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785391 Shelnutt et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) John A. Shelnutt (Tijeras, New Mexico);  Yujiang Song (Albuquerque, New Mexico);  Eulalia F. Pereira (Vila Nova de Gaia, Portugal);  Craig J. Medforth (Winters, California)
ABSTRACT Dendritic metal nanostructures made using a surfactant structure template, a metal salt, and electron donor species.
FILED Thursday, August 16, 2007
APPL NO 11/840067
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/255
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785427 Maziasz et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Shell Oil Company (Houston, Texas)
INVENTOR(S) Phillip James Maziasz (Oak Ridge, Tennessee);  John Paul Shingledecker (Knoxville, Tennessee);  Michael Leonard Santella (Knoxville, Tennessee);  Joachim Hugo Schneibel (Knoxville, Tennessee);  Vinod Kumar Sikka (Oak Ridge, Tennessee);  Harold J. Vinegar (Bellaire, Texas);  Randy Carl John (Houston, Texas);  Dong Sub Kim (Sugar Land, Texas)
ABSTRACT High strength metal alloys are described herein. At least one composition of a metal alloy includes chromium, nickel, copper, manganese, silicon, niobium, tungsten and iron. System, methods, and heaters that include the high strength metal alloys are described herein. At least one heater system may include a canister at least partially made from material containing at least one of the metal alloys. At least one system for heating a subterranean formation may include a tubular that is at least partially made from a material containing at least one of the metal alloys.
FILED Friday, April 20, 2007
APPL NO 11/788858
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal treatment
148/327
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785428 Branagan
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Daniel J. Branagan (Iona, Idaho)
ABSTRACT The invention includes a method of producing a hard metallic material by forming a mixture containing at least 55% iron and at least one of B, C, Si and P. The mixture is formed into an alloy and cooled to form a metallic material having a hardness of greater than about 9.2 GPa. The invention includes a method of forming a wire by combining a metal strip and a powder. The metal strip and the powder are rolled to form a wire containing at least 55% iron and from two to seven additional elements including at least one of C, Si and B. The invention also includes a method of forming a hardened surface on a substrate by processing a solid mass to form a powder, applying the powder to a surface to form a layer containing metallic glass, and converting the glass to a crystalline material having a nanocrystalline grain size.
FILED Monday, January 05, 2004
APPL NO 10/753167
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Metal treatment
148/561
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785492 Jang et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S) Bor Z. Jang (Centerville, Ohio);  Aruna Zhamu (Centerville, Ohio);  Jiusheng Guo (Centerville, Ohio)
ABSTRACT Disclosed is a process for exfoliating a layered material to produce nano-scaled platelets having a thickness smaller than 100 nm, typically smaller than 10 nm, and often between 0.34 nm and 1.02 nm. The process comprises: (a) charging a layered material to an intercalation chamber comprising a gaseous environment at a first temperature and a first pressure sufficient to cause gas species to penetrate into the interstitial space between layers of the layered material, forming a gas-intercalated layered material; and (b) operating a discharge valve to rapidly eject the gas-intercalated layered material through a nozzle into an exfoliation zone at a second pressure and a second temperature, allowing gas species residing in the interstitial space to exfoliate the layered material to produce the platelets. The gaseous environment preferably contains only environmentally benign gases that are reactive (e.g., oxygen) or non-reactive (e.g., noble gases) with the layered material. The process can additionally include dispersing the platelets in a matrix material to form a nanocomposite. The process also can include an additional process of re-compressing the nana-scaled platelets into a product such as a flexible graphite sheet.
FILED Tuesday, September 26, 2006
APPL NO 11/526489
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/378.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785548 Rohrbach et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Ronald P. Rohrbach (Flemington, New Jersey);  Peter D. Unger (Convent Station, New Jersey);  Gary B. Zulauf (Findlay, Ohio);  Daniel E. Bause (Flanders, New Jersey);  Russ Johnson (Elmhurst, Illinois);  David R. Rockwell (Waterville, Ohio)
ABSTRACT Disclosed is a fuel filter for removing sulfur containing compounds from an internal combustion fuel stream. In one embodiment, the fuel filter comprises at least one column comprising an adsorbent. In one exemplary embodiment the adsorbent is capable of removing sulfur containing compounds, especially sulfur containing aromatic compounds, from fuels used in internal combustion engines, especially diesel fuels. Also disclosed is an apparatus for extending the life cycle of a post combustion emission control device. In one exemplary embodiment, the apparatus comprises a fuel filter for removing sulfur containing compounds from an internal combustion fuel stream and an emission control device. Finally, a method for removing sulfur containing compounds from an internal combustion fuel stream is disclosed. In one exemplary embodiment, the method comprises passing a fuel through a fuel filter capable of removing sulfur containing compounds, storing the removed sulfur containing compounds, releasing a portion of the stored sulfur containing compounds, and sending the portion through the engine and into an emission control device.
FILED Tuesday, July 22, 2008
APPL NO 12/177526
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/211
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785728 Masel et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Richard I. Masel (Champaign, Illinois);  Yimin Zhu (Urbana, Illinois);  Robert T. Larsen (Champaign, Illinois)
ABSTRACT A direct organic fuel cell includes a fluid fuel comprising formic acid, an anode having an electrocatalyst comprising palladium nanoparticles, a fluid oxidant, a cathode electrically connected to the anode, and an electrolyte interposed between the anode and the cathode.
FILED Friday, April 02, 2004
APPL NO 10/817361
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785740 Amine et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) Air Products and Chemicals, Inc. (Allentown, Pennsylvania)
INVENTOR(S) Khalil Amine (Downers Grove, Illinois);  Jun Liu (Naperville, Illinois);  Krishnakumar Jambunathan (Macungie, Pennsylvania);  Brian Keith Peterson (Fogelsville, Pennsylvania);  Gennady Dantsin (Allentown, Pennsylvania)
ABSTRACT The invention relates to an improvement in a cell which is normally susceptible to damage from overcharging comprised of a negative electrode, a positive electrode, and an electrolyte comprised of an overcharge protection salt carried in a carrier or solvent. Representative overcharge protection salts are embraced by the formula:
MaQ
where M is an electrochemically stable cation selected from the group consisting of alkali metal, alkaline earth metal, tetraalkylammonium, or imidazolium groups, and Q is a borate or heteroborate cluster and a is the integer 1 or 2.
FILED Friday, April 01, 2005
APPL NO 11/097810
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/199
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785747 Armstrong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) Worldwide Energy, Inc. of Delaware (Oak Ridge, Tennessee)
INVENTOR(S) Timothy R. Armstrong (Clinton, Tennessee);  Michael P. Trammell (Clinton, Tennessee);  Joseph A. Marasco (Kingston, Tennessee)
ABSTRACT A fuel cell unit includes an array of solid oxide fuel cell tubes having porous metallic exterior surfaces, interior fuel cell layers, and interior surfaces, each of the tubes having at least one open end; and, at least one header in operable communication with the array of solid oxide fuel cell tubes for directing a first reactive gas into contact with the porous metallic exterior surfaces and for directing a second reactive gas into contact with the interior surfaces, the header further including at least one busbar disposed in electrical contact with at least one surface selected from the group consisting of the porous metallic exterior surfaces and the interior surfaces.
FILED Monday, April 11, 2005
APPL NO 11/103333
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/459
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785790 Church et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Robi D. Mitra (Chestnut Hill, Massachusetts)
ABSTRACT Disclosed are improved methods of making and using immobilized arrays of nucleic acids, particularly methods for producing replicas of such arrays. Included are methods for producing high density arrays of nucleic acids and replicas of such arrays, as well as methods for preserving the resolution of arrays through rounds of replication. Also included are methods which take advantage of the availability of replicas of arrays for increased sensitivity in detection of sequences on arrays. Improved methods of sequencing nucleic acids immobilized on arrays utilizing single copies of arrays and methods taking further advantage of the availability of replicas of arrays are disclosed. The improvements lead to higher fidelity and longer read lengths of sequences immobilized on arrays. Methods are also disclosed which improve the efficiency of multiplex PCR using arrays of immobilized nucleic acids.
FILED Tuesday, May 08, 2007
APPL NO 11/745806
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786037 Wang et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Hsing-Lin Wang (Los Alamos, New Mexico);  Wenguang Li (Elgin, Illinois);  James A. Bailey (Los Alamos, New Mexico);  Yuan Gao (Brewer, Maine)
ABSTRACT Metal-polyaniline (PANI) composites are provided together with a process of preparing such composites by an electrodeless process. The metal of the composite can have nanoscale structural features and the composites can be used in applications such as catalysis for hydrogenation reactions and for analytical detection methods employing SERS.
FILED Thursday, January 11, 2007
APPL NO 11/653004
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786253 Paulauskas et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Ut-Battelle, LLC (Oak Ridge, Tennessee);  Sentech, Inc. (Oak Ridge, Tennessee)
INVENTOR(S) Felix L. Paulauskas (Knoxville, Tennessee);  Terry L. White (Knoxville, Tennessee);  Daniel M. Sherman (Knoxville, Tennessee)
ABSTRACT An apparatus for treating polymeric materials comprises a treatment chamber adapted to maintain a selected atmosphere; a means for supporting the polymeric material within the chamber; and, a source of plasma-derived gas containing at least one reactive oxidative species whereby the polymer is stabilized and cross linked through exposure to the oxidative species in the chamber at a selected temperature. The polymer may be directly exposed to the plasma, or alternatively, the plasma may be established in a separate volume from which the reactive species may be extracted and introduced into the vicinity of the polymer. The apparatus may be configured for either batch-type or continuous-type processing. The apparatus and method are especially useful for preparing polymer fibers, particularly PAN fibers, for later carbonization treatments.
FILED Thursday, May 14, 2009
APPL NO 12/466092
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
528/480
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786894 Polk et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Robert E. Polk (Idaho Falls, Idaho);  John M. Svoboda (Idaho Falls, Idaho);  Phillip B. West (Idaho Falls, Idaho);  Gail L. Heath (Iona, Idaho);  Clark L. Scott (Idaho Falls, Idaho)
ABSTRACT A sensing platform for monitoring a transmission system, and method therefor, may include a sensor that senses one or more conditions relating to a condition of the transmission system and/or the condition of an environment around the transmission system. A control system operatively associated with the sensor produces output data based on an output signal produced by the sensor. A transmitter operatively associated with the control system transmits the output data from the control system.
FILED Tuesday, June 20, 2006
APPL NO 11/425287
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/870.70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787719 Vawter
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sardia Corporation (Albuquerque, New Mexico)
INVENTOR(S) G. Allen Vawter (Corrales, New Mexico)
ABSTRACT An optical data latch is formed on a substrate from a pair of optical logic gates in a cross-coupled arrangement in which optical waveguides are used to couple an output of each gate to an photodetector input of the other gate. This provides an optical bi-stability which can be used to store a bit of optical information in the latch. Each optical logic gate, which can be an optical NOT gate (i.e. an optical inverter) or an optical NOR gate, includes a waveguide photodetector electrically connected in series with a waveguide electroabsorption modulator. The optical data latch can be formed on a III-V compound semiconductor substrate (e.g. an InP or GaAs substrate) from III-V compound semiconductor layers. A number of optical data latches can be cascaded to form a clocked optical data shift register.
FILED Friday, September 11, 2009
APPL NO 12/558025
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07788334 Blumrich et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Matthias A. Blumrich (Ridgefield, Connecticut);  Dong Chen (Croton on Hudson, New York);  Alan G. Gara (Mount Kisco, New York);  Mark E. Giampapa (Irvington, New York);  Philip Heidelberger (Cortlandt Manor, New York);  Martin Ohmacht (Yorktown Heights, New York);  Valentina Salapura (Chappaqua, New York);  Burkhard Steinmacher-Burow (Esslingen, Germany);  Pavlos Vranas (Danville, California)
ABSTRACT A method for passing remote messages in a parallel computer system formed as a network of interconnected compute nodes includes that a first compute node (A) sends a single remote message to a remote second compute node (B) in order to control the remote second compute node (B) to send at least one remote message. The method includes various steps including controlling a DMA engine at first compute node (A) to prepare the single remote message to include a first message descriptor and at least one remote message descriptor for controlling the remote second compute node (B) to send at least one remote message, including putting the first message descriptor into an injection FIFO at the first compute node (A) and sending the single remote message and the at least one remote message descriptor to the second compute node (B).
FILED Tuesday, June 26, 2007
APPL NO 11/768784
ART UNIT 2451 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/212
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE41612 Brinker et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) C. Jeffrey Brinker (Albuquerque, New Mexico);  Yunfeng Lu (New Orleans, Louisiana);  Hong You Fan (Albuquerque, New Mexico)
ABSTRACT An evaporation-induced self-assembly method to prepare a porous, surfactant-templated, thin film by mixing a silica sol, a solvent, a surfactant, and an interstitial compound, evaporating a portion of the solvent to form a liquid, crystalline thin film mesophase material, and then removal of the surfactant template. Coating onto a substrate produces a thin film with the interstitial compound either covalently bonded to the internal surfaces of the ordered or disordered mesostructure framework or physically entrapped within the ordered or disordered mesostructured framework. Particles can be formed by aerosol processing or spray drying rather than coating onto a substrate. The selection of the interstitial compound provides a means for developing thin films for applications including membranes, sensors, low dielectric constant films, photonic materials and optical hosts.
FILED Tuesday, September 23, 2003
APPL NO 10/670187
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating processes
427/245
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07784346 Williams et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Frances R. Williams (Norfolk, Virginia);  Gary S. May (Atlanta, Georgia)
ABSTRACT Disclosed are micromachined acoustic sensors for monitoring electrochemical deposition, methods for fabricating such sensors, and methods for in-situ monitoring of electrochemical deposition processes using such sensors. An exemplary acoustic sensor includes a deformable silicon membrane, an encapsulated piezoelectric layer formed on the silicon membrane, and surface electrodes formed on the piezoelectric layer. The sensor and a loudspeaker may be used to calibrate an electrochemical deposition process. The acoustic response of the sensor is monitored over time with respect to plating thickness during electroplating of a sample to generate a predictive model defining the plating process. The predictive model may be used to monitor the plating thickness of other samples in real time.
FILED Monday, August 08, 2005
APPL NO 11/199102
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/597
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07784495 Prakash et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Manu Prakash (Cambridge, Massachusetts);  Neil Gershenfeld (Somerville, Massachusetts)
ABSTRACT An all fluid-based no-moving part micro-mechanical logic family of microfluidic bubble logic devices is constructed from complex sequences of microfluidic channels, microfluidic bubble modulators for programming the devices, and microfluidic droplet/bubble memory elements for chemical storage and retrieval. The input is a sequence of bubbles/droplets encoding information, with the output being another sequence of bubbles/droplets. For performing a set of reactions/tasks, the modulators program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the microfluidic channel sequence, utilizing the generated bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries. Various devices, including logic gates, non-volatile bistable memory, shift registers, multiplexers, and ring oscillators have been designed and fabricated.
FILED Tuesday, May 02, 2006
APPL NO 11/416449
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/806
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785180 von Ahn et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Luis von Ahn (Pittsburgh, Pennsylvania);  Ruoran Liu (Pittsburgh, Pennsylvania);  Manuel Blum (Pittsburgh, Pennsylvania);  Alexei A. Efros (Pittsburgh, Pennsylvania);  Maria Manuela Veloso (Pittsburgh, Pennsylvania)
ABSTRACT A method, comprising displaying an image to a first player, displaying a portion of the image to a second player wherein the portion of the image displayed to the second player is less than all of the image and wherein the portion of the image displayed to the second player is determined by an action of the first player, allowing the second player to submit a word, and determining whether the word submitted by the second player is related to the image. The present invention also includes apparatuses and systems.
FILED Friday, July 14, 2006
APPL NO 11/486561
ART UNIT 3714 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Amusement devices: Games
463/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785737 Teeters
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The University of Tulsa (Tulsa, Oklahoma)
INVENTOR(S) Dale Teeters (Sand Springs, Oklahoma)
ABSTRACT A sequence or array of electrochemical cells storing both digital and analog data. Both binary code and codes having a higher base may be stored in the memory device to increase information density. Such battery arrays could also provide power for the micro or nanodevice. Devices are microscale and nanoscale in size and utilize an electrical crossbar system to record and read data stored in the device.
FILED Wednesday, January 17, 2007
APPL NO 11/624073
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785900 Simons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico);  Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Peter C. Simons (Albuquerque, New Mexico);  Larry A. Sklar (Albuquerque, New Mexico);  Eric R. Prossnitz (Albuquerque, New Mexico);  Angela Wandinger-Ness (Albuquerque, New Mexico);  Mathewos Z. Tessema (Albuquerque, New Mexico);  John C. Reed (Ranch Santa Fe, California);  Dayong Zhai (San Diego, California)
ABSTRACT The present invention relates generally to glutathione derivatized beads which are adapted for use in conjunction with glutathione-S-transferase fusion proteins (generally, GST fusion proteins, which contain a fluorescent label such as fluorescent green protein) for use in flow cytometry. The present invention also relates to methods for detecting and/or quantifying interactions between a GST fusion protein and their binding partners, in particular, labeled binding partners such as fluorescently labeled binding partners. By creating glutathione beads with an appropriate high or increased site density, disadvantages often associated with low affinity systems and quick off-rates in solution may be resolved to provide a workable system and method. Methods of identifying potential agonists, antagonists and regulator compounds of proteins fused to GST from libraries of compounds represents another aspect of the present invention.
FILED Thursday, January 11, 2007
APPL NO 11/652432
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/523
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785922 Robbins
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)
ASSIGNEE(S) Nanosys, Inc. (Palo Alto, California)
INVENTOR(S) Virginia Robbins (Los Gatos, California)
ABSTRACT The present invention is directed to systems and methods for nanowire growth and harvesting. In an embodiment, methods for nanowire growth and doping are provided, including methods for epitaxial oriented nanowire growth using a combination of silicon precursors, as well as us of patterned substrates to grow oriented nanowires. In a further aspect of the invention, methods to improve nanowire quality through the use of sacrificial growth layers are provided. In another aspect of the invention, methods for transferring nanowires from one substrate to another substrate are provided.
FILED Wednesday, December 20, 2006
APPL NO 11/641946
ART UNIT 2823 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Semiconductor device manufacturing: Process
438/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786472 Stafford et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
Division of Physics (PHY)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents/Behalf of University of Arizona (Tucson, Arizona)
INVENTOR(S) Charles Allen Stafford (Tucson, Arizona);  David Michael Cardamone (Burnaby, Canada);  Sumitendra Mazumdar (Tucson, Arizona)
ABSTRACT A molecular-based switching device and method for controlling charge transport across a molecule. The molecular-based switching device includes a molecule having first and second nodes in between which destructive quantum interference restricts electrical conduction from the first node to the second node in an off-state, a first electrode connected to the first node and configured to supply charge carriers to the first node, a second electrode connected to the second node and configured to remove the charge carriers from the second node, and a control element configured to reduce coherence in or alter charge transport paths between the first and second nodes so as to reduce existing destructive quantum interference and permit flow of the charge carriers from the first node to the second node. The method applies an electric potential between the first and second electrodes, controls coherence in charge transport paths between the first and second nodes so as to maintain or reduce destructive interference between the first and second nodes of the molecule, and injects charge carriers from the first electrode into the first node and collects the charge carriers from the second node at the second electrode when the coherence is controlled to reduce destructive interference.
FILED Tuesday, March 20, 2007
APPL NO 11/688769
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786508 Perera et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) A.G. Unil Perera (Mableton, Georgia);  Steven G. Matsik (Chamblee, Georgia)
ABSTRACT Systems and methods for at or near room temperature of infrared detection are disclosed. Embodiments of the disclosure include high temperature split-off band infrared detectors. One embodiment, among others, comprises a first barrier and a second barrier with an emitter disposed between the first and second barrier, each barrier being a layer of a first semiconductor material and the emitter being a layer of a second semiconductor material.
FILED Tuesday, September 04, 2007
APPL NO 11/849464
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/184
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787009 Alpaslan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Zahir Y. Alpaslan (Los Angeles, California);  Alexander A. Sawchuk (Los Angeles, California)
ABSTRACT An apparatus and method for 3D interaction with an autostereoscopic display are presented. A motion tracking system may include video cameras that track a 3D motion of a user within an interaction volume defined by the fields-of-view of the video cameras, as the user moves a light source or other optical marker or an anatomical region of the user within the interaction volume. The motion tracking system may generate 3D tracking data containing position information about the 3D motion. An imaging system may create a virtual scene by tracing 3D virtual objects in virtual space, using the position information in the 3D tracking data. The imaging system may synthesize a plurality of views of the virtual scene, and interlace the plurality of views to generate an interlaced image to drive the autostereoscopic display and to be displayed thereon.
FILED Monday, May 09, 2005
APPL NO 11/124865
ART UNIT 2621 — Selective Visual Display Systems
CURRENT CPC
Television
348/51
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787129 Zysk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Adam M. Zysk (Chicago, Illinois);  Steven G. Adie (Belmont, Washington);  Matthew S. Leigh (Carlisle, Washington);  Julian J. Armstrong (Carlisle, Washington);  David D. Sampson (Fremantle, Washington);  Stephen A. Boppart (Champaign, Illinois)
ABSTRACT A method of analyzing tissue includes inserting a radiation source into tissue, impinging radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the tissue, and determining a refractive index of the tissue from the sample signal. The method may also include determining at least one other optical property of the tissue. The method may provide for identifying tissue as part of a biopsy method. A device for analyzing tissue may include a low-coherence interferometer and a probe optically coupled to the interferometer, where the probe includes a radiation source.
FILED Wednesday, January 31, 2007
APPL NO 11/669561
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/481
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787272 Lasseter et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Robert H. Lasseter (Madison, Wisconsin);  Paolo Piagi (Woburn, Massachusetts)
ABSTRACT A microsource is provided, which includes an inverter, an energy storage device, and a controller. The controller calculates a maximum frequency change for the inverter based on a first comparison between a first power set point and a measured power from the inverter. The first power set point is defined based on a charge level of the energy storage device. A minimum frequency change for the inverter is calculated based on a second comparison between a second power set point and the measured power from the inverter. An operating frequency for the inverter is calculated based on a third comparison between a power set point and a measured power flow. A requested frequency for the inverter is calculated by combining the maximum frequency change, the minimum frequency change, and the operating frequency. The requested frequency is integrated to determine a phase angle of a voltage of the inverter to control a frequency of an output power of the inverter.
FILED Thursday, March 01, 2007
APPL NO 11/681024
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electric power conversion systems
363/98
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE41614 Corey
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Elias J. Corey (Cambridge, Massachusetts)
ABSTRACT The present invention is directed to the synthesis and characterization of compounds having the formula: wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from the group consisting of H, OH, OR′, SH, SR′, SOR′, SO2R′, NO2, NH2, NHR′, N(R′)2, NHC(═O)R′ NHC(═O)R′, CN, halogen, ═O, C(═O)H, C(═O)R′, CO2H, CO2R′, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, and substituted or unsubstituted heteroaromatic; wherein each of the R′ groups is independently selected from the group consisting of H, OH, NH2, NO2, SH, CN, halogen, ═O, C(═O)H, C(═O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, aralkyl, and heteroaromatic; wherein each dotted circle represents one, two or three optional double bonds; wherein R7 and R8 may be are joined into a carbocyclic or heterocyclic ring system; and wherein X1 and X2 are each independently defined as above for R1-R8 R1-R6 and R9, and each further includes specific preferred groups as defined herein.
FILED Wednesday, December 17, 2003
APPL NO 10/738973
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/250
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07784559 Raper et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Randy L. Raper (Auburn, Alabama);  Eric B. Schwab (Opelika, Alabama)
ABSTRACT A subsoil ripper for subsoil tillage, where a spur is operatively connected to the shank of the subsoil ripper; for example, operatively connected to the posterior of the shank of the subsoil ripper.
FILED Tuesday, September 19, 2006
APPL NO 11/523393
ART UNIT 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Earth working
172/700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785376 Chun et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) David T. Chun (Seneca, South Carolina);  Gary R. Gamble (Seneca, South Carolina)
ABSTRACT A method to bind compounds (e.g., antibiotics) to natural or synthetic yarn or fabric, involving reacting the compounds with cyanuric chloride, a hydroxide base (e.g., NaOH), and deionized water to form reactive compounds; forming a dyebath composed of the reactive compounds, at least one nonioinic, cationic or anionic surfactant, salt (e.g., sodium sulfate), deionized water, and natural or synthetic yarn or fabric; heating the dyebath (generally for about 1 to about 100 minutes at a temperature of about 25° to about 100° C.); adding a hydroxide base (e.g., NaOH) to the dyebath and heating (generally for about 1 to about 100 at a temperature of about 80° to about 100° C.); rinsing the natural or synthetic yarn or fabric; placing the natural or synthetic yarn or fabric in deionized water and heating (generally for about 1 to about 100 minutes at a temperature of about 25° to about 100° C.); rinsing the natural or synthetic yarn or fabric; and drying the natural or synthetic yarn or fabric. Also natural or synthetic yarn or fabric bound to antibiotics prepared by the method are disclosed herein.
FILED Wednesday, November 19, 2008
APPL NO 12/273882
ART UNIT 1796 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Bleaching and dyeing; fluid treatment and chemical modification of textiles and fibers
08/543
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785440 Li
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) State of Oregon Acting by and through the Oregon State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Kaichang Li (Corvallis, Oregon)
ABSTRACT Method for making lignocellulosic composites by adhering lignocellulosic substrates together. A first variant of the method involves using an adhesive composition that comprises a reaction product of (i) first ingredient selected from a soy protein or lignin and (ii) at least one substantially formaldehyde-free curing agent that includes at least one amine, amide, imine, imide, or nitrogen-containing heterocyclic functional group that can react with at least one functional group of the soy protein. A second variant of the method involves using an adhesive composition that comprises a reaction product of (i) a protein or lignin, (ii) a first compound that includes at least one amine, amide, imine, imide or nitrogen-containing heterocyclic functional group that can react with at least one functional group of the protein and (iii) a curing agent.
FILED Tuesday, August 23, 2005
APPL NO 11/210405
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786347 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) Burnham Institute for Medical Research (La Jolla, California)
INVENTOR(S) Qihong Huang (San Diego, California);  John C. Reed (Rancho Santa Fe, California);  Bruce D. Hammock (Davis, California);  Quinn L. Deveraux (San Diego, California);  Susumu Maeda (Pasadena, California);  Hiroko Maeda, legal representative (Pasadena, California)
ABSTRACT The invention provides polypeptides comprising inhibitor of apoptosis protein (IAP) family members, such as BmIAP initially derived from Bombyx mori BmN cells, and nucleic acids encoding them, and methods for making and using these compositions, including their use for inhibiting apoptosis.
FILED Tuesday, January 16, 2007
APPL NO 11/623637
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/279
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787111 Kim et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Moon S. Kim (Silver Spring, Maryland);  Yud Ren Chen (Laurel, Maryland);  Kuanglin Chao (Ellicott City, Maryland);  Alan M. Lefcourt (Elkridge, Maryland)
ABSTRACT A hyperspectral reflectance and fluorescence line-scan imaging system is used for on-line quality and safety inspection of agricultural commodities. The system simultaneously acquires hyperspectral/multispectral combinations of both fluorescence and reflectance images of the agricultural commodities.
FILED Friday, April 25, 2008
APPL NO 12/109902
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/73
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07784363 Ihrke et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations, Inc. (Detroit, Michigan);  The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Chris A. Ihrke (Hartland, Michigan);  Myron A. Diftler (Houston, Texas);  Douglas Martin Linn (White Lake, Michigan);  Robert Platt (Houston, Texas);  Bryan Kristian Griffith (Webster, Texas)
ABSTRACT A tactile load cell that has particular application for measuring the load on a phalange in a dexterous robot system. The load cell includes a flexible strain element having first and second end portions that can be used to mount the load cell to the phalange and a center portion that can be used to mount a suitable contact surface to the load cell. The strain element also includes a first S-shaped member including at least three sections connected to the first end portion and the center portion and a second S-shaped member including at least three sections coupled to the second end portion and the center portion. The load cell also includes eight strain gauge pairs where each strain gauge pair is mounted to opposing surfaces of one of the sections of the S-shaped members where the strain gauge pairs provide strain measurements in six-degrees of freedom.
FILED Tuesday, September 30, 2008
APPL NO 12/241320
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/862.41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07784531 Li et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Jun Li (Sunnyvale, California);  Meyya Meyyappan (San Jose, California);  Carlos Dangelo (Los Gatos, California)
ABSTRACT A method for providing for thermal conduction using an array of carbon nanotubes (CNTs). An array of vertically oriented CNTs is grown on a substrate having high thermal conductivity, and interstitial regions between adjacent CNTs in the array are partly or wholly filled with a filler material having a high thermal conductivity so that at least one end of each CNT is exposed. The exposed end of each CNT is pressed against a surface of an object from which heat is to be removed. The CNT-filler composite adjacent to the substrate provides improved mechanical strength to anchor CNTs in place and also serves as a heat spreader to improve diffusion of heat flux from the smaller volume (CNTs) to a larger heat sink.
FILED Monday, August 27, 2007
APPL NO 11/900131
ART UNIT 3744 — Fluid Handling and Dispensing
CURRENT CPC
Heat exchange
165/185
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07784732 Owens et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Lewis R. Owens (Williamsburg, Virginia);  Brian G. Allan (Williamsburg, Virginia)
ABSTRACT A system for reducing distortion at the aerodynamic interface plane of a boundary-layer-ingesting inlet using a combination of active and passive flow control devices is disclosed. Active flow control jets and vortex generating vanes are used in combination to reduce distortion across a range of inlet operating conditions. Together, the vortex generating vanes can reduce most of the inlet distortion and the active flow control jets can be used at a significantly reduced control jet mass flow rate to make sure the inlet distortion stays low as the inlet mass flow rate varies. Overall inlet distortion, measured and described as average SAE circumferential distortion descriptor, was maintained at a value of 0.02 or less. Advantageous arrangements and orientations of the active flow control jets and the vortex generating vanes were developed using computational fluid dynamics simulations and wind tunnel experimentations.
FILED Tuesday, December 18, 2007
APPL NO 11/958673
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/53.B00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07786421 Nikzad et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Shouleh Nikzad (Valencia, California);  Michael Hoenk (Valencia, California);  Todd Jones (Altadena, California)
ABSTRACT The present invention relates to curved focal plane arrays. More specifically, the present invention relates to a system and method for making solid-state curved focal plane arrays from standard and high-purity devices that may be matched to a given optical system. There are two ways to make a curved focal plane arrays starting with the fully fabricated device. One way, is to thin the device and conform it to a curvature. A second way, is to back-illuminate a thick device without making a thinned membrane. The thick device is a special class of devices; for example devices fabricated with high purity silicon. One surface of the device (the non VLSI fabricated surface, also referred to as the back surface) can be polished to form a curved surface.
FILED Monday, September 13, 2004
APPL NO 10/940591
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07786503 D'Evelyn et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Momentive Performance Materials Inc. (Albany, New York)
INVENTOR(S) Mark Philip D'Evelyn (Niskayuna, New York);  Dong-Sil Park (Niskayuna, New York);  Steven Francis LeBoeuf (Raleigh, North Carolina);  Larry Burton Rowland (Scotia, New York);  Kristi Jean Narang (Voorheesville, New York);  Huicong Hong (Niskayuna, New York);  Stephen Daley Arthur (Glenville, New York);  Peter Micah Sandvik (Clifton Park, New York)
ABSTRACT A crystal comprising gallium nitride is disclosed. The crystal has at least one grain having at least one dimension greater than 2.75 mm, a dislocation density less than about 104 cm−2, and is substantially free of tilt boundaries.
FILED Monday, November 13, 2006
APPL NO 11/559146
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/103
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Education (ED) 

US 07788075 DeYoe et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) MCW Research Foundation (Milwaukee, Wisconsin)
INVENTOR(S) Edgar A. DeYoe (Delafield, Wisconsin);  John L. Ulmer (Brookfield, Wisconsin);  Rachael A. Kirchhoff (Milwaukee, Wisconsin)
ABSTRACT A visual defect simulation system receives a functional field map produced by an MRI system that relates locations in a patient's brain to locations in the patient's field of view. Planned medical operations are indicated at locations in the patient's brain and any resulting vision loss is simulated with a revised functional field map. A scene is displayed and an impairment overlay is produced from the revised functional field map that blocks the scene at locations corresponding to simulated vision loss. The overlay is translated over the scene in response to viewer eye movements detected by a vision-tracking system to present a real-time simulation of the resulting vision loss.
FILED Monday, August 15, 2005
APPL NO 11/203754
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/11
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 07785553 Taulbee
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Darrell N. Taulbee (Frankfort, Kentucky)
ABSTRACT A method for reducing the explosive potential of a nitrogen-based fertilizer product includes coating the product with a composition including a coal combustion by-product. The coal combustion by-product may be oxidized prior to coating the product, and further may be one or more of Class C fly ash, Class F fly ash, and flue gas desulfurization waste. A primary binder and one or more secondary binders may be included. The primary binder may be water. The secondary binder may be one or more of an organic and an inorganic binder.
FILED Friday, February 22, 2008
APPL NO 12/035714
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/274
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 07786855 Cheevarunothai et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Patikhom O. Cheevarunothai (Lynnwood, Washington);  Yinhai Wang (Seattle, Washington);  Nancy L. Nihan (Seattle, Washington)
ABSTRACT Traffic induction loop simulator (LOOPSIM) software, and a system and method designed for traffic research and education. The system is able to generate output signals in response to previously recorded real traffic events or simulated traffic. If directly connected to a controller cabinet or a traffic event data collection system, LOOPSIM can be used to simulate output signals from loop detectors and to test algorithms executable in the controller, or to test the performance of a traffic data collection/monitoring system. LOOPSIM can simulate different predefined patterns of traffic distributions and replay loop event data recorded by a detector event data collection (DEDAC) system or an advanced loop event data analyzer (ALEDA) at a pace responsive to controller feedback. Using LOOPSIM, many traffic system tests can be conducted for multi-purpose traffic control applications, and traffic arrival patterns can be generated for researchers and educators to test theoretical models.
FILED Monday, August 07, 2006
APPL NO 11/462878
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Electrical
340/515
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07788659 Rimlinger
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Director, the National Security Agency (Washington, District of Columbia)
INVENTOR(S) Francis S. Rimlinger (Ellicott City, Maryland)
ABSTRACT The present invention is a method of eliminating loops from a computer program by receiving the program, graphing its function and control, identifying its entry point, and identifying groups of loops connected to its entry point. Stop if there are no such groups. Otherwise, selecting a group of loops. Then, identifying the selected group's entry point. If the selected group includes no group of loops having a different entry point then replacing it with a recursive or non-recursive function, reconfiguring each connection entering and exiting the selected group to preserve their functionality, and returning to the fifth step. Otherwise, identifying groups of loops in the selected group connected to, but having different entry points and returning to the loop selection step.
FILED Tuesday, February 27, 2007
APPL NO 11/713829
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/160
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07785492 Jang et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S) Bor Z. Jang (Centerville, Ohio);  Aruna Zhamu (Centerville, Ohio);  Jiusheng Guo (Centerville, Ohio)
ABSTRACT Disclosed is a process for exfoliating a layered material to produce nano-scaled platelets having a thickness smaller than 100 nm, typically smaller than 10 nm, and often between 0.34 nm and 1.02 nm. The process comprises: (a) charging a layered material to an intercalation chamber comprising a gaseous environment at a first temperature and a first pressure sufficient to cause gas species to penetrate into the interstitial space between layers of the layered material, forming a gas-intercalated layered material; and (b) operating a discharge valve to rapidly eject the gas-intercalated layered material through a nozzle into an exfoliation zone at a second pressure and a second temperature, allowing gas species residing in the interstitial space to exfoliate the layered material to produce the platelets. The gaseous environment preferably contains only environmentally benign gases that are reactive (e.g., oxygen) or non-reactive (e.g., noble gases) with the layered material. The process can additionally include dispersing the platelets in a matrix material to form a nanocomposite. The process also can include an additional process of re-compressing the nana-scaled platelets into a product such as a flexible graphite sheet.
FILED Tuesday, September 26, 2006
APPL NO 11/526489
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/378.R00
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 07785440 Li
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
U.S. State Government
State of Oregon
APPLICANT(S)
ASSIGNEE(S) State of Oregon Acting by and through the Oregon State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Kaichang Li (Corvallis, Oregon)
ABSTRACT Method for making lignocellulosic composites by adhering lignocellulosic substrates together. A first variant of the method involves using an adhesive composition that comprises a reaction product of (i) first ingredient selected from a soy protein or lignin and (ii) at least one substantially formaldehyde-free curing agent that includes at least one amine, amide, imine, imide, or nitrogen-containing heterocyclic functional group that can react with at least one functional group of the soy protein. A second variant of the method involves using an adhesive composition that comprises a reaction product of (i) a protein or lignin, (ii) a first compound that includes at least one amine, amide, imine, imide or nitrogen-containing heterocyclic functional group that can react with at least one functional group of the protein and (iii) a curing agent.
FILED Tuesday, August 23, 2005
APPL NO 11/210405
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/330
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07788632 Kuester et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Anthony E. Kuester (Vienna, Virginia);  Wanda L. Key (Haymarket, Virginia);  Lillian Zelinski (Alexandria, Virginia)
ABSTRACT A method for evaluating the compliance of software to a standard quality process includes establishing a standard quality process that includes a plurality of stages, each of the plurality of stages corresponding to a software development process. A plurality of objective qualifiers associated with the standard quality process are defined, and a weighting factor is assigned to each of the plurality of objective qualifiers. The method also includes applying each of the plurality of objective qualifiers to a software application, and determining a field worthiness score corresponding to the correlation of the software application with each of the objective qualifiers.
FILED Friday, June 02, 2006
APPL NO 11/445201
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/100
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07784163 Suarez et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) John F. Suarez (Mission Viejo, California);  Bradley G. Weiskittel (Lake Forest, California)
ABSTRACT An extraction apparatus (40) for the removal of a riveted fastener (12) from a structure (10) includes a shaft (42) and a cutting element (62). The cutting element (62) is mechanically coupled to the shaft (42) and is configured to cut a portion of the riveted fastener (12). The shaft (42) and the cutting element (62) are configured for insertion through an inner channel (24) of the riveted fastener (12). A method of replacing the riveted fastener (12) from the structure (10) includes inserting the extraction apparatus (40) through the inner channel (24). The extraction apparatus (40) is rotated. A portion of the riveted fastener (12) that extends through the structure (10) is removed. A head (20) of the riveted fastener (12) is also removed from the structure (10).
FILED Tuesday, March 22, 2005
APPL NO 10/907129
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/282
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07785794 Schwartz et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) David A. Schwartz (Iowa City, Iowa);  Brian C. Schutte (Iowa City, Iowa)
ABSTRACT The invention provides methods to identify polymorphisms at the human TLR4 locus, as well as methods to identify individuals at risk of indications that increase their morbidity and mortality.
FILED Wednesday, February 04, 2009
APPL NO 12/365739
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07787249 Sundstrom
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Lance L. Sundstrom (Pinellas Park, Florida)
ABSTRACT Systems and methods for printed board assembly isolated heat exchange are provided. In one embodiment, a printed board assembly comprises: at least one electrical power layer; at least one electrical ground layer; a first signal layer having a first signal routing area providing electrical trace connections for signals and a first heat exchange chassis fill conductor area located adjacent to a periphery of the first signal routing area; at least one thermal interface coupled to a chassis for conducting heat from the printed board assembly to the chassis; and at least one via conductively coupling the first heat exchange chassis fill conductor area to the at least one thermal interface.
FILED Tuesday, February 03, 2009
APPL NO 12/364862
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/714
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, August 31, 2010.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100831.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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